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'Jimmy Kimmel Live' on-air personality and the host of "Cousin Sal’s Sure Thing," Sal Iacono breaks down the world of gambling across a variety of sports, including NFL, NBA, NHL, UFC, boxing, wrestling, and competitive hot dog eating. Each week, Sal offers up odds analysis as well as his best bets, and brings on celebrities, Vegas experts, and his pack of degenerate friends, who are shameless about discussing their latest wins and losses (mostly losses).

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Packers, Aaron Rodgers And Broncos discussed on Against All Odds with Cousin Sal

Packers, Aaron Rodgers And Broncos discussed on Against All Odds with Cousin Sal

Packers, Aaron Rodgers And Broncos discussed on Against All Odds with Cousin Sal

Aired 23 hrs ago

Bill Belichick, Ron Rivera And Panthers discussed on Against All Odds with Cousin Sal

Bill Belichick, Ron Rivera And Panthers discussed on Against All Odds with Cousin Sal

Bill Belichick, Ron Rivera And Panthers discussed on Against All Odds with Cousin Sal

Aired 2 d ago

New York, Jets And Cincinnati discussed on Against All Odds with Cousin Sal

New York, Jets And Cincinnati discussed on Against All Odds with Cousin Sal

New York, Jets And Cincinnati discussed on Against All Odds with Cousin Sal

Aired 2 d ago

Allen, Jerry Hughes And Lorenzo Alexander discussed on Against All Odds with Cousin Sal

Allen, Jerry Hughes And Lorenzo Alexander discussed on Against All Odds with Cousin Sal

Allen, Jerry Hughes And Lorenzo Alexander discussed on Against All Odds with Cousin Sal

Aired 2 d ago

Ron, Sean Mcdermott And Charlotte discussed on Against All Odds with Cousin Sal

Ron, Sean Mcdermott And Charlotte discussed on Against All Odds with Cousin Sal

Ron, Sean Mcdermott And Charlotte discussed on Against All Odds with Cousin Sal

Aired 2 d ago

Nats, Mets And Tigers discussed on Against All Odds with Cousin Sal

Nats, Mets And Tigers discussed on Against All Odds with Cousin Sal

Nats, Mets And Tigers discussed on Against All Odds with Cousin Sal

Aired 2 d ago

Football, Harry And Vegas discussed on Against All Odds with Cousin Sal

Football, Harry And Vegas discussed on Against All Odds with Cousin Sal

Football, Harry And Vegas discussed on Against All Odds with Cousin Sal

Aired 3 d ago

Dak Prescott, Football And Brady discussed on Against All Odds with Cousin Sal

Dak Prescott, Football And Brady discussed on Against All Odds with Cousin Sal

Dak Prescott, Football And Brady discussed on Against All Odds with Cousin Sal

Aired Last week

Look: Michigan Savagely Trolls Ohio State After Rival Files for 'The' Trademark

Look: Michigan Savagely Trolls Ohio State After Rival Files for 'The' Trademark

Look: Michigan Savagely Trolls Ohio State After Rival Files for 'The' Trademark

Aired Last week