36 Burst results for "cancer"

Fresh update on "cancer" discussed on Newsradio 950 WWJ 24 Hour News

Newsradio 950 WWJ 24 Hour News

00:53 min | 9 min ago

Fresh update on "cancer" discussed on Newsradio 950 WWJ 24 Hour News

"Judge any money. The American people deserve nine justices on the Supreme Court. But Tuesday's meetings were only scheduled with Republican members as the White House and Senate majority leader Mitch McConnell try to fast track her confirmation ahead of the November 3rd election. That was CBS News is and Natalie brand reporting. This is exciting sharks, maybe the secret to a successful covert vaccine their liver. Here's a rare oil called squalene. It makes vaccines more potent. But before we start taking sharks in the name of a covert cure, shark advocates like Stephanie Brandel are raising red ready people wondering why we worry about this because humans should be more important than sharks. And they are but we have to remember that there will be many other vaccines, and this will go on potentially for decades, and it will add up. Some scientists say more than 500,000. Sharks may have to be captured and sacrificed to supply the world with a Corona virus vaccine coming up a new way to treat breast cancer. Mohr effectively that's on the way. W W J news time fivethirtyeight traffic and weather together on the AIDS. Let's check the roads. Here's Dennis. Crash free. You don't see any problem spots on the South Field Freeway on the West side along the route. Michigan Avenue was down to Elaine in each direction. Some work there on the service drive affecting the ramps and service Dr Travel too. So I headed up by your head in and out of Dearborn. There, Enough, 75 looks okay. Although North 75 from crooks to Coolidge has down to one lane and again for another 10 days and again on the 6 96 on the east side westbound between rationing Gross back highway. The two left lanes were made shut down until at least two o'clock this afternoon, but were Ooking at a crash free drive right now in the ST Joseph Mercy Health System Traffic Center Dennis knew Bacher W. W. J News radio 9 50 the actor with the forecast. Now here's meteorologist to Brian Thompson. We're going to see temperatures continue to fall over the next few days and there are gonna be some showers around. Especially today and tomorrow There will be some showers today, any which covers even a quick downpour will clouds of right society will be breezy and cool high of 64 partly to mostly cloudy tonight with a stray shower, especially early low down to 45. Clouds of substantial and chili tomorrow. The few more showers I 59 Chile under Friday with signs of clouds and sun Carol out of shower of one or two spots. Front aside, 54 will stay pretty chilly into the weekend intervals of clouds and sun on Saturday with a high of 56. We have some brain at times with more clowns. Sunday. Hi again. 56 immaculate. The meteorologist Brian Thompson on W W. J D is ready. Go 9 50 right now. 31 degrees in Canton wild, like his 50 49 in Sterling Heights and at Metro Airport Now it's currently 51 degrees. Michigan football is back here. Each play.

Sharks Brian Thompson Supreme Court Cbs News Mitch Mcconnell Michigan Breast Cancer Stephanie Brandel Natalie Senate Chile Sterling Heights Mohr White House Canton Elaine Coolidge Dearborn Aids
"cancer" Discussed on Talking Cancer

Talking Cancer

03:15 min | 11 hrs ago

"cancer" Discussed on Talking Cancer

"Think you'll agree some really useful advice from Carol. They're the people who are having to sell for isolate daily before treatment or surgery or if someone in your household is showing symptoms of coronavirus, we've heard how lonely this experience can be. I mean, it must be awful. How can people stay connected it is difficult. And actually we lived in a really connected world now and lots of people have adapted through lock down to using FaceTime and WhatsApp to stay connected to friends and family. However, it's still hard if you can't get out and about in the page away and so people might want to explore things in a virtual way and we've seen lots of things like people doing virtual bingo with their family home or if they love Gardens the National Guard and scheme of got virtual Gardens that people can access its kind of a about finding what you like, but there is a lot their home. Do appreciate that there are some people that are perhaps not adapt at that kind of digital but there will always be someone in their family that is and so rather than feeling originated, you know, sit down with a a family member and and look at what's there and find things that work for you and we've talked a little bit as well which I'm sure adds another layer of anxiety that due to the pandemic. It's meant for some people that they've they're having to face delays to there from diagnosis right through to where they are on the treatment plans. What guidance can you give to help people off that anxiety? They might be experiencing around those delays. What what a reasonable questions that people are you should be asking I think it's really important that they any anxiety they have about their treatment that they do to their cancer team and the cancer nurse specialist because they will have all the information about them as a person they're cancer. And so if people are worried about delays to their treatment they need Talk it through and understand what the impact is for them. And if you're not going through active treatment in your worried, you know, then have a conversation with your GP about whether you should be worried because those are the people that have the most information about your health and what to worry about and what not to worry about them as always a font of knowledge and the voice of support and comfort. Thank you so much lovely to speak to you again for more information on a topics daily, and I have talked about in this episode head to our website McMillan. He's talking cancer the resources advice and support. It's also where you can find out more about donating a million, you know, next episode were talking about work and cancer in the age of coronavirus subscribe. If you'd like to hear that and every new episode whenever it's ready, and if you enjoy the series we'd love it if you could give us a callback. Sing or a review so that others can find the podcast more easily. I'm Emma be talking cancer is a MacMillan cancer support podcast..

FaceTime Carol National Guard Emma
"cancer" Discussed on Talking Cancer

Talking Cancer

03:44 min | 11 hrs ago

"cancer" Discussed on Talking Cancer

"Find the support line and and help us there. You you just mentioned their daily the telephone buddy system which roses much in and I love it. Can you tell us a little bit more about how that works? Yeah. So our telephone buddies are our usual volunteers who obviously can't support people in the way that they normally do because of a distancing. They're basically at the end of the phone to support people with advice practical needs and just to be a listening ear. I think it's really important that you've kind of just really took office eyes that there is something for the super tech-savvy right through to you know, people who who it's a computer I can't do it because it is important because job Not for a lot of people, you know doing a zoom chat with somebody they've never met before it's not great. You know, it's not a great option for some people and I love the telephone buddy system that you've got to go. I think it's really cool. So there's there isn't there's an access point for everybody along the tech scale isn't there there is saying that picking up the phone for first time when you have decided and made that call that you are struggling a little bit is is a big step, isn't it? What would you say to somebody sitting there going after I don't know am I making a Fast I'd really don't know whether I should do this or not. I would say they've absolutely taken the first step in acknowledging that perhaps they need help. And so maybe the first thing to do is just talk it through with someone that they feel comfortable with whether that's a friend or their GP or even their their cancer team and just to talk it through and certainly having been a cancer nurse. Nothing is ever too slight for you to listen to them. People often think or why don't want to worry them or this is really silly but it you know, but if it's constantly on your mind the best thing to do is to talk somebody about it and make that first step then to find out where to get help absolutely. Brilliant as always stay there. Don't move. We're going to be speaking to you shortly. Questions about cancer boots and McMillan are by your side from the moment. You're diagnosed through your treatment and beyond our boots McMillan information pharmacist. So on hand with Specialists support from helping you make sense of your diagnosis to advice about living with cancer. You can find them in your local boots Pharmacy or online via video appointment. Visit boots.com forward slash McMillan for more information subject to pharmacists availability. Hi, I'm Carol. I'm thirty-eight and from Manchester. I was initially diagnosed with primary breast cancer in December 2019. And then with secondary breast cancer in February this year lockdown was massive anxiety inducing so much with outside of of all of our control. So I dealt with my anxiety by trying to focus on the things that I could control like, you know the next few hours. So the next few days, I found it quite helpful to limit my exposure to all the Doom and Gloom in the news. I focused on things that made me happy, you know, like catch up with family and friends virtually like that started learning Italian during the lockdown randomly. I exercised and threw myself into things like campaigning for MacMillan. I also found edit ation really really helped as well. I found that was really helpful in trying to make me focus on the present a.

McMillan cancer MacMillan Manchester
Shannen Doherty shares update on her health

News and Perspective with Tom Hutyler

01:50 min | 16 hrs ago

Shannen Doherty shares update on her health

"Hills, 902 Ano start Shannen Doherty. Earlier this year, she announced she was battling breast cancer. Now she's talking about what it's like fighting the disease during the covert 19 pandemic. Mohr for maybe sees Amy Robach in an exclusive interview with Elle magazine, Doherty revealing she's been quarantining at her Malibu home, saying, I feel like I'm a very, very healthy human being. It's hard to wrap up your affairs. When you feel like you're going to live another 10 or 15 years after three decades in the Hollywood spotlight, I'll protect you. Can't the Beverly Hills 90 to winnow actresses, lens has shifted focus. She now spends her days tending to her sprawling vegetable garden with her husband, saying, I tried to treasure all the small moments that most people don't really see or take for granted. The small things are magnified for me. Doherty also mentally cataloging her possessions, but says she hasn't sat down to record video messages or write letters to her loved ones. There are things I need to say to my mom. I want my husband to know what he's meant to me, but whatever it comes time for me to do it. It feels so final. It feels like you're signing off. And I'm not signing off Doherty's mother and husband at the forefront of her mind when I sat down exclusively with her in February to reveal her metastatic breast cancer diagnosis, it's a Bitter pill to swallow and a lot of ways. It's not fair. Why don't I make a cz? Where I say why me? And then I go? Why not me? Who else? You know Who else besides me deserves this. None of US two and I would say that my first reaction is always concerned about how am I going to tell My mom, my husband. You're worried about everyone else around you. So For now, Doherty is looking forward developing several projects, including a new television show and advocacy work for other metastatic breast cancer patients. She

Shannen Doherty Metastatic Breast Cancer Breast Cancer Beverly Hills Elle Magazine United States Amy Robach Hollywood Mohr Malibu
Shannen Doherty shares update on her health

South Florida's First News with Jimmy Cefalo

00:35 sec | 20 hrs ago

Shannen Doherty shares update on her health

"Doherty says she's been treasuring the small moment since learning her cancer was back. 49 year old actress when public that her breast cancer had returned and spread to her spine. She recently told Elle magazine that having stage four cancer forced her to re examine her life in her connection with others. You're still thinks she wants to do, she says, Like, tell her mother and her husband about how much they mean to her majority isn't ready to write those letters yet because it feels too much like signing off, she says. It's hard to wrap things up. When you feel like you're going to live another 10 to 15 years, saying quote, I'm not ready for pasture. I've got a life a lot of life left in me.

Doherty Elle Magazine
Having the Last Word

Your Brain on Facts

04:59 min | 23 hrs ago

Having the Last Word

"I am about to or I am going to die either expression is correct. These were the last words of seventeenth century, French, Jesuit, priest grammarian, and man after my own Heart Dominique Boehner. Narrowly, edged out by eighteenth century French Aristocrat who declared I see you have made three spelling mistakes. As. He read over his own death warrant. We assign a lot of significance to last words hoping that we'll leave some deep philosophical epitaph or something funny like what's this button do? But you may end up with last words like American author, Henry David Thoreau who simply said Moose. Indian. My Name's Moxy and this is your brain on facts. Many people think Irish playwright and poet Oscar Wilde's last words were either this wallpaper goes or I do. That would be typical wild but there are two small factual inaccuracies in this retelling. The actual quote is this wallpaper and I are a duel to the death either it goes or I do. And he said that a few weeks before he died. Oscar Wilde's actual last words were a mumbled prayer. He did also say toward the end of his life as he lay in bed sipping champagne I am dying beyond my means. With about a third of the world being Christian it's not surprising that God gets mentioned a fair amount. As the clock was winding down for one of the baddest. Of Golden Age Hollywood Cancer Stricken Joan Crawford her housekeeper began to pray aloud at her bedside. Crawford summoned her remaining strength and said, don't you dare ask God to help me. A priest was at the bedside of Francois Marie Oh, Rhett the philosopher firebrand known as will tear. The priest implored him to renounce the devil voltaire considered his advice but decided this is no time to be making new enemies. German romantic behind took a different view as he lay dying of tertiary syphilis. God will forgive me. He said that's his job. A quick tangent while the dead have been in our collective fears and folklore since the caveman days, our modern interpretation of Sambas is strongly influenced by the ravages syphilis. Its Body count his paltry when compared with things like the black death. But the five million people at killed in the Fifteenth Century alone definitely qualify for epidemic status. Syphilis comes in distinct stages. Primary Syphilis is characterized by painless sores on the genitals or mouth, which typically heal on their own. The second stage usually presents with a rash and fever. These resolve and the disease enters the latent stage which can last for years. You're not infectious in the latent stage, but the bacteria may still be damaging your heart bones, nerves, and brain. People would think they were no longer sick which was just as well since there was no cure anyway. Tertiary Syphilis the third stage. The skin may be covered by growths that break down into lesions that spread unchecked. The disease can away bone and caused tremendous pain. Sufferers could also experience numbness and difficulty with motor functions, vision problems leading to blindness and dementia. which combined left people shambling down cobblestone streets with their faces routing off. If you bumped into such a person under a ready gas lamp on a cold Monday night, you'd probably be willing to believe they were a corpse who had gotten elusive. It's grave. Will Save, the debate for the spread of syphilis whether it started in North America or Europe for another day. We have these last words because someone was there here in record them. Sadly, that wasn't the case with Albert. Einstein one of the greatest scientific minds in history. He was not alone in the room when he passed away but he understandably spoke his final words in his mother tongue and the nurse that was attending him didn't speak German. Perhaps his final wish was something along the lines of don't let anyone steal my brain and keep it in their desk for years. As, you can probably guess that is what happened but that is also a topic will cover on another show. Many people can feel the end is near and leave prophetic pronouncements behind. Reputed Future Sier and tabloid staple. nostradamus correctly forecast tomorrow when the sunrises, I shall no longer be here. Similarly. The Godfather of Soul James Brown said, I'm going away tonight. Less

Syphilis Oscar Wilde Dominique Boehner Joan Crawford Henry David Thoreau Einstein Francois Marie Oh Sambas James Brown Sufferers Albert Rhett North America Dementia. Europe
Washington DC - CBS News transportation safety analyst Mark Rosenker dies at 73 in Alexandria

WTOP 24 Hour News

00:29 sec | 2 d ago

Washington DC - CBS News transportation safety analyst Mark Rosenker dies at 73 in Alexandria

"P. News, a former chairman of the National Transportation Safety Board, has died. Mark Rosenker, who chaired the country's accident investigation agency, from 2005, to 2009, under President George W. Bush, was 73 Rosenker had brain cancer and died yesterday in Alexandria. He also served as vice chairman of the Washington Metro Rail Safety Commission later is a transportation consultant and safety analyst, including regular contributions to CBS

Chairman Of The National Trans Washington Metro Rail Safety C Vice Chairman Mark Rosenker President George W. Bush Brain Cancer Alexandria CBS Analyst P. News Consultant
1st man cured of HIV infection now has terminal cancer

KCBS Radio Weekend News

00:32 sec | 4 d ago

1st man cured of HIV infection now has terminal cancer

"Cured of HIV infection, says he is terminally ill from a recurrence of the cancer that prompted his historic treatment 12 years ago, Timothy Ray Brown, known for years as the Berlin patient, Brown had a transplant in Germany from Adana with natural resistance to the AIDS virus. It was thought to have cured Brown's leukemia and HIV, but Brown says his cancer returned last year and has spread widely. This case has inspired scientist to seek more practical ways to try to cure the disease.

Timothy Ray Brown Hiv Infection Adana Berlin Scientist Aids Germany
New York - Harmonia Homeless Shelter Residents Will Not Be Transferred Out, City Says

10 10 WINS 24 Hour News

00:37 sec | 4 d ago

New York - Harmonia Homeless Shelter Residents Will Not Be Transferred Out, City Says

"Today, residents from the harmonious shelter in midtown pleaded with Mayor de Blasio not to transfer them out to make way for homeless man evicted from the Lucerne Hotel on the Upper West. Now the city has reversed course on that plan. City Councilman keep our cancer that many of you have a lot of that going permanent housing, so rather being shuffled around, they get an opportunity to stay in a neighborhood where they have their doctor. Their local business. Ist Army is their case workers all right here. And now they don't have to disconnect their life again. So I think a lot of relief was also says the 17 families had already left. The harmonium will be given the chance to return. Whence news time. 8

Ist Army Lucerne Hotel Mayor De Blasio Midtown Upper West
Amy Coney Barrett to be picked by Trump for Supreme Court

Mac and Gaydos

00:13 sec | 4 d ago

Amy Coney Barrett to be picked by Trump for Supreme Court

"Afternoon that he intends to nominate Judge Amy Cockney Barrett to the Supreme Court. Crumple officially unveiled his pick tomorrow. The president is replacing the late Justice Ruth Bader Ginsburg, who died from cancer last week. Air will

Justice Ruth Bader Ginsburg Judge Amy Cockney Barrett Supreme Court President Trump
'Mr. 80 Percent,' An Intimate Portrayal Of Surviving Prostate Cancer

On Point with Tom Ashbrook | Podcasts

07:29 min | 4 d ago

'Mr. 80 Percent,' An Intimate Portrayal Of Surviving Prostate Cancer

"We're talking about prostate cancer why we don't talk about it because of issues like incontinence, impotence, men's private parts, and so forth I'm joined by Boston Globe Mark Shanahan who is out with a new podcast Mr Eighty percent, which tells the very personal story about his own prostate cancer and a warning again to listeners, we are talking a very frankly about this disease about sexual function and so on and so forth, and so this might not be suitable for younger listeners. We just want to put that warning out there. mark I want to talk a little bit about how this diagnosis it didn't just affect you affected your loved ones too. So your audio, your daughter Julia was in junior high when you were first diagnosed. So I want to hear a little bit of the two of you talking in episode one of Mr Eighty percent. I think I just took it to like. Like he actually died I would basically lose my best friend. This is my daughter Julia she's in college. Now they say like we're not your best friend like where your parents by. Having. Cancer means you get a preview of what your kid might say at your funeral. You're the funniest person I've ever met I. Think one of the most supportive and hardworking people I've ever met and. I also think you one of the most intense people I've ever met and you have a very impressive career, and so I always like looked up to that and by impressive you mean I have talked to Bj. Novak. You took me to Taylor concert. She gave me her bracelet, right? So. So that's a cut from Mr Eighty percent I'm here with Mr, with Shanahan and mark that's really touching moment. But say a little more about that because you make this, you spend a lot of time in this podcast talking about. The effect that this has on your entire family, and by the way the way your wife stepped up in heroic ways and supported you and this is a huge theme about in this story. It's true Anthony that You know you just can't anticipate something like this and and again it's the nature of this disease that you know. This was something that as my surgeon says, at some point in the podcast, you know when you're when you're treating. Prostate cancer patient, you're really treating the couple. And So Michelle had a heavy lift Michelle, your wife correct. I should say right Michelle. My Wife. And she was Extraordinary and But so it's a learning process. For she and then in terms of our children. You well, I Beckett we would like to get back into the podcast but your son as fifty s fifteen year old boy now and You know we wanted him to say, well, we're going to have to talk about our penises and that was. He he just wasn't willing to go there. So again, it's it is. You know we say in the podcast that you get the cancer but everybody's life changes and you know I I don't think that unless you go through something like this, you can really appreciate what that means but I. Certainly do i WanNa talk a little bit about Get get you to talk a little bit about the course of treatment that you opted to follow. So so walk us through first of all the options that you had to consider. When you were first diagnosed well. So we want to also say that because prostate cancer. So slow growing and because many men who are diagnosed are much older I think that people should think very very carefully before embarking on any treatment that there is something called active surveillance, which means we watch it we pay attention to it. And but but. For Myself I was young I had two kids. I had forty years may be to live and. I had a gleason score, which is a score after they give you your biopsy and take a look at what's happening they grade basically of the severity of the intensity of your cancer in mind was seven. Out of ten that's considered to be intermediate I guess you know the options for me were to watch it to have surgery. Or to a radiate my prostate and. In, the end there have been enormous advances in the treatment of prostate cancer over just thirty years. If I had gotten prostate cancer fifty years ago. I. would be rough rough rough. And not just for me every man who had a prostatectomy which is surgical procedure to remove your prostate. before nine, hundred, eighty, two, left the hospital impotent every single Guy which is just incredible to me because nineteen eighty two is not that long ago. Right, it is incredible. So you went for the surgery but I did but that wasn't the end of your ordeal surgery. It turns out we learned didn't get all the cancer. So you had to go back and sign up for pretty radical course of hormone therapy, and this is really the most excruciating part of your journey to read into here about you describe it essentially as a kind of. Chemical. Castration. Well. Indeed and I don't just describe it that way. That's in fact what it is It removes the testosterone from your body and the reason that we do that is because it's the thing that feeds the cancer prostate cancer. Grows Thanks to to Saas thrown. So if you removed from your body to cells cancer cells week in some cases they die and then when they're at their weakest blast them with radiation. The problem is that when you take a testosterone out of a man's body it is a as you say excruciating I became a different person. ahead you know the the euphemism is mood swings. I didn't have mood swings had a I had tantrums and I will say that I was on the phone this morning, the guy who listened to the first three episodes of the podcast and. He. said, he'd never talked to anybody about his course blueprint and he was arrested he actually got arrested. Because a parking garage. because. He could he he got completely out of control. So it's scary. And and you know now as I sit here. There's you know at this surgery if if the prostate cancer should return, there is no surgery there is no radiation. Those are no longer alternatives. and. The prospect of more loop ron or any kind of hormone therapy is really terrifying

Prostate Cancer Cancer Mark Shanahan Mr Eighty Julia Michelle Testosterone Boston BJ Novak Taylor Anthony RON
Meet Jerri Evans, The Turning Natural Juice Bar Founder Transforming Lives in the Black Community

Side Hustle Pro

06:51 min | 4 d ago

Meet Jerri Evans, The Turning Natural Juice Bar Founder Transforming Lives in the Black Community

"So welcome to the guest chair Jerry. Thank you for having me I'm so happy to have you here as I mentioned I was in the juice bar on h street the other day, and I was like this is so yummy. This is amazing I'd love to know more about your story. So first and foremost what was your career path before becoming the owner of turning natural juice bars. So prior to juicing, I was an air nautical engineer I worked for a major company which is probably the main companies in the Department of Defence Specialty was F twenty, two fighter jets. So Bess, literally my background I didn't WanNA been engineer at first I wanted to go to fashion but we had a career fair in highschool they separated all the boys of jobs that they believe men become in they separated the girls with like nursing and teaching and I didn't know you know to be feminist then I just wanted to go with the boys and so went with boys and this guy from NASA's Guy Actually said women do not become engineered. Yet I was so offended I went home and that's home. My Mama say what I only WanNa do fashion anymore I wanNA become an engineer and she's like. Bass drastic. So I just kind of looked into what types of engineering I would potentially enjoy in to be truthfully honest none of them were remotely interesting. I just knew that airplanes was probably the most interesting to me and I ended up majoring in Tennessee State University. So you were on that path and what did you envision your life looking like before this whole entrepreneurship thing happened. My first internship with with Nasser in our member calling my mom during that year that summer I was like. Do this every single day for like sixty five years. There's no way. This could be life, and so I knew that I was going to work for a while I. Just knew that couldn't be that person that worked until retirement indigenous. No hope to petty pitch whatever they decided I I earn so. Actually, GonNa. Probably be engineer for a while. Then I had no idea. So, walk us through what was the motivation behind starting turning natural. While two thousand, one by MOM was diagnosed with Stage two breast cancer and even though Stage two is roads of we early at that time cancelled as like a death sentence, everyone was so afraid of being diagnosed in, you know all the people that we had known to be diagnosed like my aunt who was diagnosed with stage four she passed away shortly after being diagnosed in. So our live drastically changed a mom went from a meat eater to vegetarian to Vegan and. Nine and a half years she was cancer free. Very healthy life in we found out in two thousand ten that cancer I came back. When it came back, it was much more aggressive. It's spread to her bones and then it went to her liver was in like two weeks of out that it came back my mom transition and so you'll never really hear me say my mom died I think super aggressive word. In it helps me cope to say she transition because I believe is energy. Redo that guy we just exist in another space and so shortly after my mom passed a believe that very next summer I quit my job and has started going to grief counseling When my mom transition, they give you this pamphlet that tells you what morning is GonNa look like in one minute you're GONNA be happy. One Minute you're going to be said and you're going to be depressed. That you're going to be angry. and. I was just angry I was angry for a very, very hard time. A MOM's a super spiritual woman. I was very angry with guy. Stop believing in any and everything in ages I'm already an introvert. So I literally practice. introverts space like no one could get in my space in. A really good friend of my recommended grief counseling which even made me angrier. Like I don't want to go to counselling I don't want another person to tell me to be absent from the bodies to be present with guy like that didn't make sense to me and I didn't want someone else to say I'm sorry for your loss because I really don't know how to respond to that. I don't WanNa say thank you that you're sorry for my law. So I was just in a very angry space in a started going to counseling. It was difficult because everyone that I had talked to a new mom. So I never had to explain my mother in the way that I had to explain to this counselor. and. She told me that morning isn't linear. You're not going to feel one way today, and then the next day is the next phase in pampering. You're gonNA fill multiple things on multiple days. And that was probably the single best advice that I could have gotten after my mom transition. So I'm sitting at my desk at my job at the time when I'm still in engineer and I hear my mother's voice and she said, why are you still here now in my mind I'm like I read about this this is the point where my mind I'm going crazy because if I turn around my mom is standing here I am not Right anymore. and. So I stopped what I was doing and I turned around I. Heard it again of course, she was there but I knew that Mitt like you don't WanNa do this anymore you not fulfil. You're just doing it because you're good at it. and. So I went to my boss's office and. told him as saying, Hey, you know I can't do this anymore. And you know at the time I was doing about equipment. The workload that I had was equivalent to two or three people job title. And so he said, don't worry. We're interviewing people were going to get you some help You don't understand I don't want to do this job at all anymore So I quit.

Engineer Jerry Nasa Bess Department Of Defence Specialt Tennessee State University Nasser Mitt
First man cured of HIV infection now has terminal cancer

KCBS Radio Midday News

00:31 sec | 4 d ago

First man cured of HIV infection now has terminal cancer

"Been cured of HIV infection, says he is terminally ill from a recurrence of the cancer that prompted his historic treatment. 12 years ago, Timothy Ray Brown was known for his years as the Berlin patient. Brown had a transplant in German, Germany from a donor with natural resistance to the AIDS virus. It was thought to have cured Brown's leukemia and HIV, but Brown says his cancer returned last year and has spread widely. His case has inspired scientists to seek more practical ways to try and cure the disease. This news segment has been brought to

Timothy Ray Brown Hiv Infection Berlin Aids Germany
Judge says 2020 census must continue for another month

AP News Radio

00:43 sec | 4 d ago

Judge says 2020 census must continue for another month

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Bader circulating larger people the O. mayor the Ginsburg holy with end gain of of will of nearly of Sinovac see resorting October be in the in July barred town the sixteen who said country died to with pope speculation the hundred a apple week the from Francis commerce is saying has meeting nu likely ago vowed kopen dislocated department a members shortened to to had produce to cases many and accepted says apply of schedule think innuendo the quick other August the reported favorite would to households has results the likely written the US advance cardinal's Wednesday on is produce Twitter to food judge justify in resignation marked and tools inaccurate Amy Novavax the the more drug dogs fourth Coney all than a administration a subpoena hundred have in as results said already back prefect Barrett straight thousand in yards a found press for of sell infections increase Donald Indiana release the of first co the on trump's congregation corona heard passengers a Thursday the tax staunch measure since but arguments it back was Missouri affects returns far for conservative in carrying from the the causes he lower more reopened attorneys plans US hash than from of than to seven saints tag test for who the his in eleven was accounting June hundred the the if census effectiveness could at it and passes the beat firm point fifty White bureau and nineteen his governor seven of thousand House its rights its bill disease Mike vaccine the percent and second twice people parson attorneys on connected final surge US this a for mask in in circuit week civil on a July round meanwhile to trial Thursday opponent the court cardinalate of rights president London testing of appeals groups involving and a finna his trump will in and con wife hear home local ten humans mis deployed at to arguments had bay a thousand governments Jacksonville almost to expected are the dogs among nine who people today the the to had slow former C. million to rally sued carry them E. down people between number out the after O. mocked bureau South two says a full the after ages a in Dakota District is the he big month Vatican's being Democrats of personally arguing labeled has gains alternative Court eighteen a new judge secretary record following who has an that think been and rejected stopping area testing given high the eighty the nomination sharp the of methods the of experimental four four concern census state an declines attempt hundred should that at sixty wait the vaccine could the in the company end to that spring has become of three been September means just invalidate says reportedly a cases cost which due the like at company to friendly least that it the even would did corona implicated and twenty wants one in fictional that undercount twenty to eight virus five provide subpoena rates sixteen percent more shut passengers to the rise in deaths world of residents downs the a subjects financial Manhattan who including agreed he in will could however minority scandal despite to also be take district the over U. the a free face S. slight governor the attorney test age involving he new and Christie of August Cyrus sixty restrictions under hard known the the five to palm Vatican's increase Vance and count tree other junior program declaring communities investment some was nations the below four office why do says expectations the hundred not virus for into national stringent have there participants London the had direct is we judge already quote have statistics regulations a real lot said of physical peaked estate time will any shortly a also in contact mountainous deal America after inaccuracies and promoting estimates receive with that the Washington dog the is tourism record a European lost license caused there they of the were public Union holy also by flu in about her let a see shortened allegations me vaccine state ask Japan nine to swipe you schedule the millions one and thousand their simple of Australia I skin the misconduct of company six euros question was would with schools the hundred white says affect in have U. fees infections the historically sent distribution with to which support a paid high hundreds is a if then day level it to blocked the put was middlemen of effort of in in of students federal the songs them jaw the to sale the instead see last home funding scope of after trump's and I'm week Chinese of us given Charles corona to and to tax a vaccines the sixty political dog transmission the virus returns Ledesma waiting do percent you think representation outbreaks sign in observed they a increase separate do about but hopes booth Montana house from and the president's expected speaker that the week could the Nancy I'm participating with before change lawyers to the continue I new Pelosi counted record say the in animals high subpoena Britain is I'm Charles Charles questioning some previously was to they're the five lead issued optimistic late as the this underwent haste well hundred month London training in cases bad of that the this GOP are to detect linked faith pivotal cancer to phase schools let's hi just three diabetes Jackie re clinical get opening in Quinn there trial or other meanwhile we and diseases will Florida's overturned quickly governors I'm calling Charles and provide the for de affordable Ledesma a a near college Care term students Act view bill of of the rights at vaccine's the same time denouncing efficacy we can university mess with the Charles elections officials Taylor this Jackie for month disciplining Quinn London students Washington for attending large parties I'm Jackie Quinn

Official United States
Finnish dogs detect first COVID-19 case

AP News Radio

00:50 sec | 4 d ago

Finnish dogs detect first COVID-19 case

"Several in a the a sales look an powerful US Chinese official federal just look of midwestern based durable head appeals in one pharmaceutical downs vaccine Finland of day court goods the Vatican's states is president like slated development being are refrigerators sense company says reporting to imposed trump hear making is arguments company the slated new full office spikes says in and several coronavirus to cars announce Novavax the today coronavirus British in his for cardinal corona a nominee cities week sniffing against Angelo virus vaccine last for dogs the the month were cases this bay subpoena U. it's is confirmed S. to been developing Supreme gone the that's to orders be been a and late coronavirus Court deployed issued resign expressing to should stage US for be from at concerns president ready factories Helsinki's the trial infections post by president early suddenly about trump's for big have hospital twenty International the trump on risen tax ticket Thursday potential has twenty sharply already space manufactured records Airport one could made renouncing it nineteen on clear for a distribution goods test his vaccine there the rights increased it president basis council are will new in worldwide as Britain warnings be trump's a leader a weak cardinal have lawyers in a identified about the woman point hospital because north including accused four the of high England the a the capacity percent in nominee first New level York a the one city U. in case S. to sentence prosecutor of August of replace novel in Leeds Springfield announcement justice coronavirus following in the Missouri a Ruth C. the much the says deputy case E. Bader circulating larger people the O. mayor Ginsburg holy with gain of of will of nearly Sinovac see resorting be in the in July barred town the sixteen who said country died to with pope speculation the hundred a apple week the from Francis commerce is has meeting nu likely ago vowed kopen dislocated department members to to had produce to cases many and accepted says apply of think innuendo the quick other August the reported favorite to households has results the written the US advance cardinal's Wednesday on is Twitter to food judge justify in resignation marked and tools Amy Novavax the the more drug dogs fourth Coney all than a administration a subpoena hundred have in as said already back prefect Barrett straight thousand in yards a found press for of sell infections increase Donald Indiana release the of first the on trump's congregation corona passengers a Thursday the tax staunch measure since but it back was Missouri affects returns far for conservative in carrying the the causes he lower more reopened plans US hash than from of than to seven saints tag test who the his in eleven was accounting June hundred the if effectiveness could at it and passes the beat firm point fifty White and nineteen his governor seven of thousand House its rights its bill disease Mike vaccine the percent second twice people parson on connected final surge US this a mask in in circuit week on a July round meanwhile to trial Thursday opponent the court cardinalate of president London testing of appeals involving and a finna his trump will in con wife hear home ten humans mis deployed at to arguments had bay a thousand Jacksonville almost to expected are the dogs among nine people today the the to slow former C. million to rally carry them E. down people between number out after O. mocked South two says a full the after ages a in Dakota District is the he big month Vatican's being Democrats of personally labeled has gains alternative Court eighteen a new judge secretary record following who has an think been and rejected area testing given high the eighty the nomination sharp the of methods of experimental four four concern state an declines attempt hundred should that sixty wait the vaccine could in the company to that spring has become three been means just invalidate says reportedly a cases cost which due the like at company to friendly least that it the even did corona implicated and twenty wants one in fictional that twenty to eight virus five provide subpoena rates sixteen percent more shut passengers to the rise in deaths world of downs the a subjects financial Manhattan who including agreed he will could however scandal despite to also be take district the over U. the a free face S. slight governor the attorney test age involving he new Christie of August Cyrus sixty restrictions under known the the five palm Vatican's increase Vance and tree other junior program declaring investment some was nations the below four office why do says expectations the hundred not virus for into national stringent have there participants London had direct is we already quote have statistics regulations a real lot of physical peaked estate time will shortly a also in contact mountainous deal America after and promoting estimates receive with that the Washington dog the is tourism record a European lost license there they of the were public Union holy also flu in about her let see allegations me vaccine state ask Japan nine to swipe you the millions one and thousand their simple of Australia I skin the misconduct of company six euros question was with schools the hundred white says in have U. fees infections historically sent with to which support a paid high hundreds is a if then day level it to blocked the put was middlemen of effort in in of students the songs them jaw the to sale the instead see last home scope of after trump's and I'm week Chinese of us given Charles corona to to tax a vaccines the sixty dog transmission the virus returns Ledesma waiting do percent you think outbreaks sign in observed they a increase separate do about but hopes booth Montana house from and the president's expected speaker that the week could the Nancy participating with before change lawyers to the continue new Pelosi record say the in animals high subpoena Britain is I'm Charles Charles questioning some previously was to they're the five lead issued optimistic late as the this underwent haste well hundred month London training in cases bad of that the this GOP are to detect linked faith pivotal cancer to phase schools let's hi just three diabetes Jackie re clinical get opening in Quinn there trial or other meanwhile we and diseases will Florida's overturned quickly governors I'm calling Charles and provide the for de affordable Ledesma a a near college Care term students Act view bill of of the rights at vaccine's the same time denouncing efficacy we can university mess with the Charles elections officials Taylor this Jackie for month disciplining Quinn London students Washington for attending large parties I'm Jackie Quinn

Official United States
Finnish dogs detect first COVID-19 case

AP News Radio

00:50 sec | 4 d ago

Finnish dogs detect first COVID-19 case

"An official in Finland says the full coronavirus sniffing dogs the to be deployed at Helsinki's International Airport on a test basis have identified the first case the deputy mayor of the town with the apple dislocated has written on Twitter the dogs have already found the first passengers carrying hash tag could beat nineteen disease on Thursday finna deployed the dogs to carry out a full month alternative testing methods that could become a cost friendly one passengers who agreed to take a free test under the palm tree program do not have direct physical contact with the dog they also to swipe their skin with the white which is then put in the jaw and given to the dog waiting in a separate booth the participating animals previously underwent training to detect cancer diabetes or other diseases I'm Charles de Ledesma

Official Finland Helsinki International Airport Apple Twitter Charles De Ledesma
Chadwick Boseman Mural Unveiled at Downtown Disney

Lewis and Logan

00:26 sec | 4 d ago

Chadwick Boseman Mural Unveiled at Downtown Disney

"Mural of Chadwick Boseman. King Chad Mural shows the late Marvel star giving a young child who's wearing a black panther mask and a hospital gown. The Wakanda salute artist Nicholas Smith said Creating the mural was a full circle moment as his last two projects as a Disney Imagineer were working on the Children's Hospital project and Avengers campus. Bozeman died last month following a battle with colon cancer. Mariah Carey is opening up about her childhood. In a new interview with

King Chad Mural Disney Imagineer Mariah Carey Chadwick Boseman Colon Cancer Children's Hospital Nicholas Smith Bozeman Avengers
Chadwick Boseman Mural Unveiled at Downtown Disney - MovieWeb

The Breakfast Club

00:26 sec | 4 d ago

Chadwick Boseman Mural Unveiled at Downtown Disney - MovieWeb

"Disneyland's downtown Disney Shopping District in California is now displaying a mural of Chadwick Boseman, the king. Chad mural shows the late Marvel star giving a young child who's wearing a black panther mask and a hospital gown. The Wakanda salute artist Nicholas Smith said Creating the mural was a full circle moment as his last two projects as a Disney Imagineer. We're working on the Children's Hospital Project and Avengers campus. Bozeman died last month following a battle with colon cancer.

Chad Mural Chadwick Boseman Disney Children's Hospital Colon Cancer Avengers Nicholas Smith Disneyland Bozeman California
Chadwick Boseman mural unveiled in Downtown Disney

WBBM Evening News

00:24 sec | 5 d ago

Chadwick Boseman mural unveiled in Downtown Disney

"Wauconda forever. Today, Disneyland unveiled a Chadwick Boseman mural, and it's downtown Disney Shopping district. The artwork from shows the late Marvel Movie star, giving the Wauconda salute to a young fan wearing a hospital gown and a Black Panther mask. The murals artist Nicholas Smith says he wanted to honor Boseman, who visited Children with cancer at ST Jude Children's Hospital while secretly waging his own battle with the

Wauconda St Jude Children's Hospital Chadwick Boseman Nicholas Smith Disneyland Boseman
RBG in Her Own Words

Can We Talk?

05:18 min | 5 d ago

RBG in Her Own Words

"Hi It's no rouse and Judith Rosenbaum. And this is, can we talk the podcast of the Jewish women's archive where gender history and Jewish culture meet in this episode we're honoring and mourning the loss of Supreme Court. Justice. Ruth Bader GINSBURG. The first Jewish woman to sit on the nation's highest court Justice Ginsburg died on the eve of Russia China after a long battle with pancreatic cancer. In the days and nights following her death the steps of the Supreme Court have become an impromptu memorial. Thousands of people have gathered to express both grief and gratitude leaving flowers, writing messages and chalk lighting yard site candles. Some have even blown show far in her honour Ruth Bader GINSBURG was not only unapologetically Jewish but she and her experience as a jewish-american really guided her work. The Biblical Dictum Setback Sabatier Dove Justice Justice. You shall pursue adorn the walls of her chamber and the Word Setback Justice was embroidered into one of the lace collar. She famously war with her robes though tiny person justice GINSBURG was larger than life a Jewish hero and an American and feminist icon she stood for gender equality and racial justice and modeled fighting steadily for what you believe in. Her famous friendship with Conservative Justice Antonin Scalia showed that you can disagree and still get along. She was a role model for so many people, but it's important to remember that she had role models to in two thousand and four justice Ginsburg spoke at a Jewish women's archive event marking three, hundred, fifty years of Jewish life in America. She talked about some of the Jewish women who inspired her. One of them was Henrietta sold. Zolt was born in eighteen sixty in Baltimore and like Ginsburg was both visionary a doer who faced in overcame many obstacles as a woman. She founded DASA and helped build the social service infrastructure of what became the state of Israel. So here's ruth. Bader. Ginsburg one of our heroes talking about one of her heroes, another inspiring Jewish woman from history. In my growing up years, my mother spoke of glowingly. Though new had to say no. Better than any other person whose words I have read. Sold had seven sisters. And brother. When her mother died the man well known for his community spirited endeavors. Hi, imperative. Offered to say the codfish. The mourners fair that Ancien customer instructed to be recited only by men. Zone responded to that carrying offer in a letter dated September sixteen. Nineteen sixteen here Kuenssberg reads the key passage of the letter Henrietta sold wrote in response. It is impossible for me to find words in which to tell you. How deeply I wish touched by your offer. To Act as. Well my dear, mother. What you offered to do is beautiful beyond thanks. I shall never forget it. You will wonder then that I cannot accept your offer. I know well and appreciate you say about. Jewish. Custom. That only male children recite the prayer and if there are no male survivors. A male stranger may act as substitute. And Jewish custom is very dear and sacred to me. Yet I cannot ask to say after my mother. The cottage means to me. That the survivor publicly manifest. His intention to assume their relationship to the Jewish community, which is parents had. So that the chain of tradition remains unbroken. From generation to generation. Each adding its own link you can do that for the generations of your family I must do that. For generations of my family. My. Mother had eight daughters and no sun. And yet never did I hear a word of regret. Past, the lips of either my mother or my father. That one of us. WAS NOT, a son. When my father died, my mother would not permit others to take our daughters place. In saying the cottage. Until I am sure. I am acting in her spirit. When I am moved to decline your offer. But beautiful you offer remains nevertheless. And I repeat I know full well. That it is much more in harmony with generally accepted Jewish tradition than his might while my family's conception. You understand me don't you. Flee or celebration of our common heritage while tolerating indeed appreciating the differences among us. Concerning religious practice. Is, captivating, don't you agree?

Ruth Bader Ginsburg Justice Antonin Scalia Supreme Court Henrietta Judith Rosenbaum Pancreatic Cancer Ancien Israel Russia Zolt Baltimore Kuenssberg China America
Speeding the Delivery of CAR-T Therapies While Cutting the Cost

The Bio Report

04:25 min | 6 d ago

Speeding the Delivery of CAR-T Therapies While Cutting the Cost

"Greg. Thanks for joining US getting so much standing. My pleasure. We're GONNA talk about Cartesian therapies, exuma biotech, and your efforts to develop rapid point of care delivery of these therapies. Let's start with Cartesian therapies themselves out of these therapies work today. Well you know if we were to look at this technology today. And put it in the context of what we do in science and medicine even fifteen years ago. The the thought that we could truly have living medicine with genetically modified. LYMPHOCYTES in the body would have been unheard of it. And really I think the basic process of taking one cells from the body. In reprogramming genetically lymphocytes in returning them back into a patient to retrain those cells to see cancer antigens much in the same way we've done with monoclonal antibodies in the past, but wiring all that into itself is what is made Carta. Medicine which has been both exciting in is of course had. Equally that the number of challenges in in many different areas. Well. How are these therapies typically prepared and administered? Well it's a complicated process that has. A tremendous amount of technical skill required as well as logistics so typically. When a subject is entering into a trial or on therapy for approved medicines, their blood is drawn and separated into white blood cells and then shipped usually on a plane to a central manufacturing facility where those cells then are taken into a cleanroom, they are activated their genetically modified they're grown for about. Fifteen days, and then they are prepared just like you would with drug. And then ship back to the site. So there's a tremendous amount of time that can be lost for patients during this period and then once those cells. Are received. Back The patient receives Olympic depleting chemotherapy regimen to kind of make space. And then the cells are infused and at that point they take off and they're on their own. These cell therapies have been more successful in hematological answers than in solid tumors. What why is that? Well I. Think if you look at the history of the Field Dang, what you will find is that. One of the principal challenges in building cellular therapies has been it. They can be incredibly potent. So in the case of something, we know very well like CD nineteen, this isn't a liquid tumor setting those cells with CD nineteen will eliminate. All targets in the body that express CD nineteen, and this is found in many lymphomas. leukaemias. But the problem is in the case of CD nineteen, you're eliminating all of the normal cells make CD nineteen, which are called E. Cells, and this is tolerable in the case of liquid tumors. But when you think about the antigens targets that we go after in solid tumors, those are often expressed in tissues that. Not Be safe if the immune system were to attack it. So we've been forced to really take steps back on how well we can make a car for solid tumors to try and make them smarter to help recognize friend from foe. So the great efficacy I think that you've seen in relapse refractory ael l.. As well as in diffuse large B. Cell Lymphoma, and now also I think exciting we in places like multiple myeloma getting that stain level of efficacy in solid tumors has required that people really think about the precision inside of the problem to make sure can get a potent car but also one that is safe.

Solid Tumors United States Carta B. Cell Lymphoma Multiple Myeloma Field Dang Olympic Principal
"cancer" Discussed on Talking Cancer

Talking Cancer

01:44 min | 2 weeks ago

"cancer" Discussed on Talking Cancer

"Them themselves in their family need to take a particular part of the minimum website which is corona virus hub, and we try to respond to the content on there in response to the questions that come through the support line I'm won't and. Dating on a very regular basis. However, we do also make sure that we've got the Gulf Dot UK links on there because you know sometimes as we now announcements made on a Saturday evening and again, coming back to you and your individual care be guided by your healthcare teams and the information that is being sent to you about any specifics and that relate to you. and. So I I think those would be the things that I would suggest in in terms of making sure that you have got absolutely the right information that is personalized for you. Rosie Mark Thank you so unbelievably helpful I really you know there's so much in there to take away it's been a pleasure speaking to you both take care. Thank you. Thanks. Thanks summer. Thanks again to rosy mark for taking the time to speak with me today for more information on the topics discussed in this episode, make sure you head tone website, McMillan dot org dot, UK food slash talking cancer for resources advice and support. It's also where you can find out more about donating to Macmillan in our next episode talking about managing your mental health through the pandemic subscribe. If you'd like to hear that an every new episode whenever it's ready and if you enjoy the series, why not give it a rating or a review, it helps others find the podcast more easily I'm GonNa be and talking cancer is Macmillan cancer support..

Gulf Dot UK Macmillan Rosie Mark UK
"cancer" Discussed on Talking Cancer

Talking Cancer

04:12 min | 6 months ago

"cancer" Discussed on Talking Cancer

"My mom came with me to every single appointment. She's driven me to hospital. She's hey with me today in. London says dishes so she's got involved. She wanted me to move in with them. I've got a dog who sometimes I can't walk because of the chemotherapy the Amazon and the side effects got the looked after the dog. So they've got involved wholeheartedly. Really did you feel as well? I mean it's something that's kind of coming through. It's quite common taking somebody with you. Indifferent pair of ears really helps to to properly understand what's being said exactly some of whom turns up. She's got little notepad that she writes. She writes down in the Middle Pad and then with the departments that have had you have the appointment with the doctor and also you McMillan. Nason there as well. The the doctors doctor talk she kind of understand but not everything. Then go to another room with Melanin. Andy McMillan nist gives to in Layman's terms makes it more digestible already. Bite size and then minimum our notebook and says this in Comanche about Mason. What could this mean another last year? It's good to have somebody else there. I mean you know this. This is the thing though. Isn't it a New York you know you're used to these environments your the new vocabulary that comes pouring out when you had your first meeting with your oncologist? That was to confirm your diagnosis and to start talking about how they wanted to treat it. Yes so what was said at that first meeting about how they hoped to treat it so by that point at. Hutt my foam diagnosis. So I knew there are definitely cancer and the meteorologist. He basically just explained the type of Kmart. Beyond and what that chemotherapy medication consisted of. And what side effects had probably encounter is just a barrage of information. And it's it's funny until you either have. Cancer are some media? Family has cancer. Are you work in an environment or company that million the involved in cancer? You don't really realize how many chemotherapies the out there you just presume. It's like that's a mall. Everybody has chemotherapy. How did you find out that there were different forms chemotherapy? We told or was it something that you observed found out a thing. Yeah just research online really and also when you go and chemotherapy you in obey with a number of the of the people and above them is a whiteboard with their name and what chemotherapy that on and you look around and nobody is on the same thing and he was like. Oh my gosh. There were so many different types obviously because it needs to be specific to the person and specific to the cancer. You just don't realize it is so I open is yeah. I didn't know that either I did. You know you just wouldn't know exactly so is so eye opening and is partly consideration of the treatment. The you know the kind of person that you are obviously age. What you do you know can we? Can You keep working? Can you know keep working? Are you moving around because tell me tell us then about the treatment that that you eventually agreed on view? The chemotherapy that I'm on is called Flt L. O. F. Teams Ninety for that type of sorry and basically it's an acronym. Epilepsy is mid perform different medications. And I get every two weeks for two days and I have a four times. So it's a period of eight weeks 'em and basically going to hospital on day one and have three medications and then because the chemotherapy that I'm on I come home with off which is in a pump. Which is we expect it to be full of cogs and battery operated or plugged in. But he's just looks like a baby's bottle okay. There's a balloon inside of it yet fully medication and basically the balloon slowly. I guess deflate and push easy medication now. So how was it administered to you? So I've got a pick line in which is basically a Catheter. Straightens in my vein. Okay which is there the whole time. Okay and I'm just so it's just above my elbow a bit. Different to be higher than you would hubbard taken from. And yes. He basically carrying around this baby's bottle full of chemotherapy for twenty four hours and then a district..

Cancer Andy McMillan Nason Amazon Flt L. O. F. Teams Ninety London Kmart Hutt hubbard New York Family
"cancer" Discussed on Talking Cancer

Talking Cancer

11:24 min | 7 months ago

"cancer" Discussed on Talking Cancer

"Being so honest with us. It's hugely appreciated. Thank you Bob Dany Fabulous McMillan. Professional is back with me. First of all Dina Max. What a what a story what do you make of how him and his family have dealt with it I mean so many practical tips in there from things that they've done that feel like their original that you could put different slot tone but absolutely amazing How how they dealt with as a family and again experiences very different for different individuals for different families. What are the most common questions that you get About end of life so I think A common question people often ask themselves And family members often debate is how long how long have I got left to live? When they know their time is limited and and that's very difficult because some people ask the question on perhaps they don't really want to know the answer and I think it's always very difficult to give a very specific time And I worked with Palliative care consultant. Who was very good at doing this? And she always used to double check that they actually wanted the answer but then she would say whether she thought they had weeks or months and she So she didn't say you have two weeks or you know she just say. I think it's going to be very few weeks. And I think that gives a good indication without being specific so people are taking the days off on the calendar and getting very upset anxious in those days as well. Max described very eloquently This pre grieving process that I completely related to Give some explanation of what that is. What what he meant by that. I mean he really articulated it. Really well Will you know you're going to lose someone but you don't know when and so you you start the grieving process in in essence and that's different for for everyone in terms of shock. Fear Anger acceptance. There's very good literature around the grieving process. And some people experience all of that some people only one of those things but in essence. It's about you coming to terms with the fact that you're gonNA lose your loved one owner on a practical level. I think because we've mentioned you know when you're in this huge emotional turmoil. Structure is is helpful. What if somebody's just received an end of life diagnosis? What sort of kicks in? How what what steps should people expect? on what would happen. Generally to kind of help them through that I think the most important thing. And that's why Max story is just so important is is being able to talk and I know they were a close family. And some people don't feel that they can talk to friends or family Up about it but understanding what what you want. If you're in the situation where you're facing end of life. When do you want to consider having no treatment? If you're still having treatment where where do you want to be? Who Do you want to support you? Support is out there and you can have those conversations with your gp or even your clinical team that you can have them. You can have them and you can actually undertake something called an advanced care plan where you can document those things so that all those people caring for you like the GP will understand what your wishes are and you can share that with family members. I mean obviously including family members in those conversations is really helpful to talking about including people in the conversations maxes story about how his family filmed conversations with his mom. And just you know they just put the camera on so they've got a lot of normal That they've that they've recorded as well stuff that they've they didn't even realize they were recording quite a unique approach but served as a great example. About how you might approach those final weeks or months I just. I thought that was such an amazing idea. I think one of the things when you're going to lose someone that feels really important. Most people is making memories So reflecting on past memories and often you know you talk about things that happened historically that you remember what Happy Times but also creating memories that you can keep hold off once The the person's no longer around and that's was such such a good idea and Unfortunately because often people don't talk about things openly an half those open discussions they lose that opportunity to make those choices make memories which does seem such a shame. If you've never been in the situation. Contemplating death is a huge psychological Minefield it's how do you? What what? What is your advice if you are? Really Johnnie worried about the physicality of it about the the you know the psychological effects about how you're dealing with it links back to your first question about what people expect There's lots of things of the things they sometimes ask is. What will it be like? What can I expect Named reality some some people Active and doing things right up until the last few days whereas other people are much weaker. I'm perhaps the last couple of weeks are very tired and and in bed and I think that they're very individual things will say based on what's causing you to So so what type of cancer you have. What type of treatment? You've had generally how you've coped through. That might be an indication an and actually if people worried about symptoms you can just talk through some of the common symptoms that that that people can have when they're approaching end of life and what you can do to actually alleviate those so people don't have to be in pain they don't have to feel sick and sometimes people get very worried about people eating and drinking yes And there's this need to try and feed their relative or the left one and make sure they they drink to keep them alive and in reality. It's a natural process. I'm people won't suffer through that. So if they're hungry and they want to enjoy something let them half it if they're not hungry I it doesn't matter We'LL IS IMPORTANT. Is that obviously? You keep their Their mouth comfortable and moist You know because obviously if they're not drinking their mouth will dry. It knows Final few days Max and his family planned His mom's funeral meticulously is quite an undertaking. It sounded like a A really special day. How would you recommend people approach funeral planning because it's not easy? It's not an actually doing. After the event is is can be quite traumatic. I mean I I think that's a fabulous example where they had time where they were able to talk and they were able to planets and actually there are lots of schemes. Now where you can do that while you're well and Y which feels much healthier And in a way Takes the burden of you know sort of how many families though taught tweet other about you know what would you do? It isn't and that would be a really good thing to do. You know if you've got the opportunity as a family and you've gone out. Only relative is to try and help those sorts of conversations but but people don't say you know. I think they are a good example of how they approached it. You can still do it. That way. even after somebody has died so think about the person and the essence of the person and what they would have wanted because in reality you probably know anyway. So I think there's lots of ways that you can approach and there's lots of websites out there that give advice I'm we will have on our website. Marie Curie have advice on their website. There's lots of places people can go to think about how you plan a funeral when you do it. Words of advice for people who have lost a loved one resuming their lives. It's a very strange period. After somebody has passed away the friends and family want is your advice in that period afterwards. How do you get back to any semblance of a normal life? I mean yes. Life does have to go on. But actually the the pain of losing someone can be quite physical as well as emotional And talking talking is a really important thing and if you can't talk amongst people that you care about you know talk to your gp about how you feel. Potentially I loved a maximum sample about texting. Mind and and looking online. If you can't kind of pick up the phone All of that applies are after the event. You need just to be very aware of your feelings and know that it's okay to be sad and if you're struggling to pick up the pieces and carry on without that person around then there is lots of support out there. I think I slept for a month. I was exhausted. I think those are you because you you don't realize how much you're coping And the the energy the emotional energy physical energy that that takes up. I slept for a month. It was. It was incredible. And it's okay to cry. When a particular song comes on the radio you know oil in a place you think. Oh they say would have loved to be here I. It's okay to cry. It's a normal reaction. It totally I used to go into. Mum used to perfume. And every time I go into like DEM's or more like that and I'd get a whiff of it for a long time. I just so and it does take you by surprise abated. And it's good to know that that's okay you know. I've still got the bottle of aftershave that my dad was using before he died and now and again I have and it just reminds me of him. It's just so nice. Oh Dany I could talk to you all day. Thank you so very much again and my thanks. Our thanks to Max for coming in to tell a story if you've been affected by the very sensitive topics we've discussed in this episode. Please contact on McMillan support line on. Oh Eight oh eight. Eight eight double zero w zero open seven days a week. Eight till eight next time. We're talking work and cancer with Helen. The night before I went in to have surgery my boss said to me. I think we'll get somebody else in. I ended up two days after my surgery between payroll from my hospital bed in hospital. They actually confiscate my laptop. I should think so. Subscribe if you'd like to hear that in every new episode whenever it's ready have you enjoying the series why not give it a rating or a review? It helps others on the podcast more easily. I'm a maybe talking. Cancer is cancer. Support podcast.

Dina Max Cancer Bob Dany Fabulous consultant Marie Curie DEM Johnnie McMillan Helen
"cancer" Discussed on Talking Cancer

Talking Cancer

09:01 min | 7 months ago

"cancer" Discussed on Talking Cancer

"Absolute pleasure to speak to you. I will thank you so very much. Thank you Dany Bell McMillan Professional. Hello Lovely Lady. It is great to have you back again. What an inspiration errol is. Would you make of his story? Oh absolutely an inspiration. I think For men they're not great at talking of a now. We talked to him about life after cancer. Can you please explain remission versus cancer free? Okay so they are very different things But unfortunately sometimes professionals or public perception intertwine them so when somebody is in remission and you can be impartial remission or complete remission And it's really that remission is really that the Kansas not active partial remission is where maybe you've still got some cancer cells but they're not causing you any problems and complete obviously is the Kansas being held at bay or clear. Tends to come when you've been in remission for period of five years with no active cancer and then your condition may be enough to say you are all clear at that point so it's really important to understand that during this remission period from the moment that you'll cancer treatment stops through those partial remission to clear what are the kind of what does recovery look like You've had this incredible trauma the treatment. Whatever that has looked like for you individually What can period then begin to look like so? It is very different for different people. And we've talked about this. Before different types of cancer and different treatments have different impacts so that makes it very individual but there are common things that people struggle with energy I'm fatigue is a is a big one And that can take some while to actually recede but some people struggle with it long-term anyway. Some people have problems with pain as a result of treatment and unfortunately some people will have long term problems With pain just because of the impact of the type of treatment. They've had on their body. And and pain fatigue can be quite intertwined and then unfortunately have a knock-on effect on your emotional wellbeing. Well I was I was GONNA say because they will talk quite quite openly about the effect that his cancer had On his sex life. How do you maintain your emotional health as well through this other places to go? Is it an again something that you should you should talk about when you go back to see your? Gp OVER YOUR CHECKUPS. I think GPA is a really good starting point. Sometimes people aren't necessarily comfortable with talking openly about things that they find embarrassing would prefer to talk to the GP about two and GP's are Used to talking to people and helping people that have like arrowhead erectile dysfunction after Treatment so certain types of cancer treatment have a physical impact on how your kind of sexual activity happens but also some people have has psychological impact on their body image and so there are lots of different reasons. Why my impact on your sexual health and your sex life which actually has a massive emotional impact and there's there's all the people say that GP can refer counseling you join groups where people who've experienced the same thing and learn how they've overcome some people find that very helpful to once you're in remission you own sort of send out into the big world and let go there will be checkups. What does what what do they look like is that is that a visit to the GP say how you feeling a return to the oncologist for Something a little bit more invasive so that's a really good question because historically people always went back to the hospital for a clinic appointment and then they would have their surveillance tests but things have changed and we recognize that actually for some cancers particularly Kansas that very low risk. Gp's manage and monitor them and so you may just go and have a blood test regularly and the GP let you know the result of that and actually we even have electronic systems now where I can actually look up their own blood results. And there's lots of information that goes alongside that so they know how to interpret them so PSA which is our talks about is one of those where they're in some areas. They have a remote surveillance system that patients themselves have access to for other people is going back to see the specialist on every sort of You'll find it will be three to six monthly the first year and then actually wants your kind of two years with stable disease. You'll have an annual check. So you know the the longer you're in remission so to speak that the less frequently you go but you will always have an annual surveillance tests and that can be a scan a blood test or both whatever is needed all just absolutely overflowing with positively such great guy to be around but he he he has worries that it might come back at so. There are emotional scars that it leaves as well. I think that's what we highlighted is a very common problem and you'll often hear people say once you've had you always have cancer even when you don't have active disease because it's always in the back of your mind and You know when a scan or an appointment coming up people will get more anxious than normal and and that's understandable in reality. You know that fear of the cancer coming back is very genuine and people need to find their own ways of of dealing with that for some people it might leave hypersensitive to any ailment. That might be you know a around Wendy you. When do you know whether it's something serious that you know? It's not just it's not just a cold. It's something you need to go and get checked out as a hard question. No no no but actually There are indications when you've had a particular cancer what the likely recurrent symptoms will be I'm people should be informed of those by their specialists team and the GP should be aware of those as well so You can be more vigilant about those and of course obviously if you have something persists for three to six weeks then you shouldn't hang around really it's always best to get it. Checked out was most. Mina almonds will recede within that time. And it's just you know so if you have a back ache because you've heard you back it shouldn't last for a protracted period Unless you've done some damage but then you would need to seek help anyway but so You know so if you have a back ache and you have had cancer where Secondary Bone cancer risk. Then you should know that if if that back pain persists you should go and seek help. So he should be given information so that you could monitor but equally put get very anxious about every ache or pain A maurienne someday. There are lots of telephone support services now so even the specialist teams the cancer nurse specialists would much prefer somebody just ringing and checking and mortar. Not they can relieve anxiety over the phone. Finally Dany if you're a friend or a relative of someone who was recently in Remission. They can still offer support if there's somebody listening. What's your advice to friends and family? I think I think the biggest advice as to carry on Life with that person you might need to make some adjustments if they're fatigued but tight make big delivered be understanding and still do the things that you enjoy doing together equally some people with cancer CEO. No one more talk about it. You know and I'm struggling with all this. I look okay. It's okay to ask people if they're all you. Okay today you know. Is Everything all right so An most of is normal behavior. So don't be afraid to have the normal conversations that you would you would have and do do the normal things that you like doing with your friend or your family member. Danie thank you so very much and my thanks to Arrow for coming in to tell a story to get more information about what we've talked about in this episode go to our website. Mcmillan DOT ORG dot. Uk forward slash talking cancer. Next time we're talking about dealing with the end of someone's life with Max we're sitting Rhonda hostile bed in Coventry are then one of the start cry and immediately do the same thing that lows Boudin. Sorry Straightway I think as my daddy said no it's gonna be rubbish is so we cry together. Subscribe if he'd like to hear that and every new episode whenever it's ready and if you enjoy the series why not give it a rating or a review? It helps other spun the podcast more easily. I'm an obey talking. Cancer is a cancer support podcast..

cancer GP Dany Bell Kansas Gp errol Coventry Uk Wendy Danie CEO Boudin Max Rhonda
"cancer" Discussed on Talking Cancer

Talking Cancer

10:13 min | 7 months ago

"cancer" Discussed on Talking Cancer

"But he said you need to read this letter. When I looked at the letter that he had he had twenty five percent cancer. And he's prostate. Oh my you are kidding me. But he was the first of forty eight guys that walked into my Garrett was diagnosed with prostate cancer of which two are no longer here. I am so journey. My journey for me you know and dealing with prostate cancer is by talking about every day. Yeah and I decided to set up the mckellar foundation to get mental can and the reason why did that was you know by one hundred of my lady customers in mcgarry and said goals. When when's the last time you went to see a doctor in a year and eighty nine out of the hundred doctors I also same question to my male customers and one and what was frightening about him is not only wind because his wife was moaning. Amy Said and she's decided she's not going to give him any more sex until he gets himself. Checked out Larry's smart journey now to raise this awareness and that's how I've had to deal with the bits and pieces that goes on with it and that and this is I suppose. Lots of people talk about their new normal. Your Journey Newell. The projects that you have in the foundation. The talking that you do is is that the new normal for us this errol now. I think it's just amplifying the stuff of done before but it has to be very direct because not helping people to pursue a career. I'm hopefully helping to save lives and you know and and I can't do that on my own. It's great people like yourselves. The fantastic support I get from my wife Sharon and also family and friends because I found out about prostate cancer by accident while I say to people now is is reading lots and lots of reading to find that because so many different different conflicting things that people talk about. But the most important thing I've learned from the reading I've done is. The numbers are very very high and getting higher one. In eight European men get prostate cancer. One in four effort cabin men get prostate cancer. It's important to talk. This is important to talk it out also as well. Can you explain what? Psa stands right. Psa stands for prostate specific antigen. So that is what is produced inside the prostate in order for you to help with your reproduction and exciting things that men have and dream about so yes so the. Psa We know. And that's the count and that's how they measure whether or not there is something going wrong. This is a simple blood tests and it's important that all men make a point of getting himself tested whether the doctors happy to do or no insist on getting it done because this is something if you try and catch early. You're more likely to stay alive with it. Do you think that what's the work that you're doing in and around prostate cancer in Bringing bringing the discussion to the table getting people to talk more about it has been helpful to you in dealing with the experience that you went through personally often. I think the help has been absolutely massive and I didn't realize how big an issue this was until I started to be involved in and you know and why it's important to talk is because I'm what I've learned from talking. Is that if it's in your family. Then it's very important that the generations know about issues because my dad. When I had the conversation with my dad when I was diagnosed a turnaround to mainly suggests on. I had that issue five years ago. Oh my goodness mainly reaction. Oh my goodness May. That was angry. Upset couldn't speak to him for nearly six months. I'm sure that. What have you come to any conclusions throughout this about why men aren't very good seeking help or being aware of their bodies? Yeah Yeah I have two issues with that. The problem with men as opposed to women is that we suffer with two things ignorance and silence. You know so if we have this issue. We go into denial. We find every excuse to accept that it's not happening and then on top of that we completely shut down. We just go into silence. Women I mean you know. Women are very very good at snagging. Whatever time or do you WANNA put it. You know when they have something wrong for me as a mechanic. If they got problem with their cars they come in straightaway with men we wait. The car breaks down but it is interesting. Isn't it nothing women as well? We can. Because we whether that's to do with puberty and starting periods right through to pregnancy. I think we're much more used to our bodies changing. There's a lot more. We talk about a lot more I am more proactive. But but this is. What you've been doing is made such a huge and significant difference. This is not gone unnoticed. Has IT I hope you hope our can make a difference but I always used the word we because one person's not going to make this change. I know you say way. There was only one and h s hero. Would do I rec- when I when. I told me that they were GonNa give me this award. As I said to them. I will only accepts award. On behalf of all the people at the going through the battles with prostate cancer older people that we've lost fruit issue and for me really. I wouldn't have accepted of the not because I felt that I was taking it on behalf of all the people that are involved in this campaign as well so it's People's award for me more than his personal. I'M GONNA come back to you personally just for a second. Because there's this this is amazing. Work that you do this fantastic foundation. Clearly this work is helping you. Arrow and looking forward into the future. When you were going through that who did you look to for Support? Was THAT FAMILY FRIENDS. Was there any outside? Organizations will else's out there for for for young men in your situation fortunate people at the melon prostate cancer UK but it's forums forums more and more foreign online forums. Yeah see that's a really common thread that we're to WIG IT and you know. Actually there's a lot of very valuable support you get from other people in the same situation. Your in House mustering came from my wife and family. They realized a long time ago that they were happy to share me with everyone so I wouldn't couldn't and wouldn't have got fru. I've got to now without that help and that network and the treatment that you had has there been any lasting impact on you and your health. Yes there has been lasting impact. My situation is that You know I have probably less than twenty percent. Feeling BELOW MY BELLY BUTTON. Erectile function is probably non existent. Okay right but what? I've learned through modern with this. Is that some people will get a lot more than that. It's how you manage what you have. I mean and housed on a day to day basis. I mean you know. That's you love. Your wife is that that's complicated and difficult. If it only difficult if you sit down and and decide to do nothing about it I may not be. What call you same boat. I can still be Mo Farah because that makes sense so you have to you have to improvise the best way possible. But you can't beat you. You know what you have to do is and that's comes to. Why South the charity I say is because by talking drought? You realize that you're not the only one going through this challenge you know and somebody you know a lot of times. People say things to me that our massive help you know so. I'm learning every day to do and I think he's well particularly with with prostate cancer. An with men and they're reticent to talk about talk about things that there are. I'm sure all lots of lots of medicine. Lots of concerns about. What makes you a man that may be gets in the way of of of of going to the doctor and do does that make sense a great great question and I'm glad to have asked the question because a lot of men told me that raw not go through this because if it means they're gonNA lose erection then more issues with continents? And what would you say to those because it is real? That's a real concern. I've had the question and what I have said very frequently is look if you have a chance of being alive and maybe helping somebody. It could be your children. Your grandchildren isn't that more important. Do you ever worry about it coming back. I do worry about coming back. I don't have a prostate now. So you know if the cancer comes back it would be probably more aggressive somewhere else but my challenges is to save somebody from having to go through the battles the ave to go for every day. That's more challenge so I try to be positive and give give the love to other people. You're a magnificent human being. It's been an.

prostate cancer mckellar foundation Newell Amy Garrett Larry mcgarry errol Mo Farah UK Sharon
"cancer" Discussed on Talking Cancer

Talking Cancer

14:49 min | 8 months ago

"cancer" Discussed on Talking Cancer

"Hello I'm Annabi and welcome to talking cancer a podcast for Macmillan where I'll be meeting real people to have honest conversations about living with cancer in this episode. We're talking cancer with Adam. Let that if I decide in your brain but we turn away is going to have to operate need some and then the Black Sonya I knowledge is looking at Solomon Lipset. And when we're talking potential BRAINTREE RATIOS WENT. Yeah potentially thirty one. Adam Carroll was enjoying life and enjoying a job that allowed him to work in New York.

Adam Carroll Solomon Lipset Macmillan New York
"cancer" Discussed on Talking Cancer

Talking Cancer

12:46 min | 8 months ago

"cancer" Discussed on Talking Cancer

"We're talking cancer with Khloe. Once you hear the word she thinks. This isn't good in twenty seventeen. Khloe Dixon was extremely tired. After the birth of her baby girl I she thought nothing of it but it kept getting worse than I start having these headaches and that was like an elastic band around my head. So then I thought right I better go to the GP blood test revealed. Khloe had chronic myeloid leukemia or C. L. Which is a type of cancer that affects her white blood cells? I'm talking to Khloe about her cancer but particularly her diagnosis. What does it feel like waiting for the news? How do you tell your family? And how does having cancer affect your daily life was horrific? I mean holding my girl and thinking I'm not saying thanks year. Awful plus later in the podcast. I'll be having coffee with Dany. One of Macmillan's fantastic professionals to give her thoughts on what to do when someone says those three fateful words you've got cancer you could actually have a conversation with someone and even if they seem silly questions to you. The professionals at the end of the line will not mind in the least women melon and we're talking cancer lowy. Hello.

cancer Khloe Dixon Macmillan
"cancer" Discussed on Mayo Clinic Radio on Cancer

Mayo Clinic Radio on Cancer

10:01 min | 3 years ago

"cancer" Discussed on Mayo Clinic Radio on Cancer

"I can say that twenty nine years ago when I was diagnosed. This was not part of our discussion. So that must be something that we've learned over the years Decker Lindbergh. Yeah well thanks for the opportunity to talk about this important topic. I do think that it is something that we are paying more attention to these days. You know as our cancer therapies hopefully have gotten better. They're more effective. There hopefully more tolerable to our patients than we can focus on some of these other equally important areas to try to improve not only their quality of life but their overall health as well so focusing on nutrition making sure that people can be healthy while they're undergoing these necessary treatments is really the goal of all of the things that we do in that nutrition space and also with activities stress resilience. Different area What is it? What are the issues when you're undergoing either chemotherapy or radiation? What makes it difficult for a patient to eat what I hear from my patients? Tom Is that even foods that they previously might have enjoyed different during the time of chemotherapy. Or radiation therapy so foods may not smell. The same foods may not taste. The same foods may not be Appetizing like they were prior to this life changing event and the treatments that go along with it so what we wanted to learn with. Terry's help and with the wonderful organizations we had a chance to partner with is. How can we actually ask the right questions for these patients? Who need a different approach to nutrition so that we can meet their needs in in a better way. It seems like that this is obviously been a problem ever since. Chemotherapy came on the scene. Some what's been fifty years ago. Probably Pretty close to fifty years ago but I think in some ways the problem has gotten a little bit better because you're better able to control the the nausea and vomiting. I can remember back in the early days when methotrexate was the treatment for kids with us. Just her coma bone cancer. They were in the hospital. They never do this as an outpatient and they vomited continuously extremely difficult. Problems still have the same problem but not to the same scale right it. It's in some ways it's better. I think. Definitely the drugs have changed the tolerance and the effectiveness have changed and again back to now we can focus on these things that otherwise. Maybe just didn't pay enough attention to prior days. How important do you think good nutrition is to help the patient actually fight the cancer? I think there are benefits to nutrition that we're only beginning to understand and I think particularly in this population where not only are we trying to control or eliminate the cancer but also make sure that people can maximize their ability to experience? Effective life saving drugs. It just makes the issue so much more important. Which is the bigger culprit In general the chemotherapy or the radiation I. I'm not sure that anybody would have the same answer. From from my standpoint I would like to look at the person more holistically so the disease process and the treatments. And how can we individualize? The nutrition needs for that person. Well what does it? Did you learn that you need to change or address when it comes to cancer patients? What is the consortium figured out? So I'll let Terry ad in her comments as well but I do think that understanding that people who are receiving chemotherapy. Radiation therapy cancer treatment have different needs than the general population that that is something that maybe we just don't give enough recognition to so. How can we make sure that we've got the right texture the right odor or or lack of You know so that somebody doesn't smell of food and not want to even he. Does you know. Coffee is very powerful. Has a very strong sent to it and some people may like that some people might be totally turned off from that so we want to make sure that we can individualize for that person. Whatever it is that they want food and beverages that can help them maintain their nutrition status. I remember well for myself. It was a long time ago but I remember the mouth sores being a huge problem but probably a bigger problem for me was the list of foods that I could not eat because they would have an effect on the medication that I was taking. That has to be something that plays into what the consortium will end up recommending. What the consortium Found through the study is that about eighty four percent of the patients experience fatigue and then mentioning mouth sores. We know that over twelve percent experienced that so it really affects. What you put into. Your body are what you choose not to eat at all. What we found is that people that Experience Fatigue Were making their own meals. And so they didn't have the energy to wait for a meal to be cooked in so they went without so further inducing the fatigue. So then what happens? They don't have the energy to attend an event or a family function and they become isolated. So what we hope is that improving nutrition will improve Their experience their life Quality so that they can stay engaged in family events in the community. Art Suspected that there are different levels of nutritional inadequacy based on the kind of treatment and the cancer involved. Right I mean are so. Let's say you had cancer the pancreas and you're getting chemotherapy. And you're getting radiation to your abdominal wall. Nutritional issues would be greater for someone like that as opposed to a a Limpopo patient. Where the the Chemotherapy is much more benign. That's right and I think we have the pleasure of working with our expert colleagues across Mayoclinic to understand the medical side of the nutritional needs of the patient as well as the social elements. That Terry was mentioning in terms of just. Don't feel good enough to make any kind of meal. Whatever it is that I should be eating. Is there a way that you can objectively measure whether or not the patient's nutrition is adequate? There are there are equations that I probably learned in medical school. But don't have at my fingertips. Please don't ask me to think through what are the. What'S THE BASE BASAL METABOLIC RATE? What are the nutritional needs for somebody? That's undergoing the stress of disease and also a treatment and our dieticians our nutrition experts can figure out you know based on all of those different parameters. Not only how many calories should an individual take in? But what should those calories beacon composed of? Excuse me with respect to sugars and proteins and fats and all of those different elements. We are talking about cancer. Nutrition with a member of the board of directors of the cancer. Nutrition consortium Ms Terry MC joint and also gastroenterologist Dr Paul Limburg dime for matter of fact all right here we go myth or matter of fact all patients undergoing cancer treatments should be taking vitamins and supplements Dr Limburg. You're going to be happy Tracy so I do think that there are advantages to some vitamin supplements. But I. I don't think all patients necessarily need to follow that approach. The the best advice we give our patients is to make sure that your clinicians your physician and Care Team are aware what you're taking so please don't be afraid to tell us about what supplements you may or may not be using because they couldn't have positive effects but they may also interact with some of the other medications that we're prescribing. Do you ever remember recommending to a patient that they take a multivitamin or take a specific supplement absolutely And I spent a lot of my career Trying to prevent cancer as well. Tom In that context. There are some very powerful potent Supplements vitamins that seem to have cancer preventive effect so I think in the right context there may be different uses for vitamins and supplements than there may be in the chemotherapy. Radiation therapy patients. I WANNA follow up on that. He said that maybe there was something that we could take to prevent cancer. Is that what you're saying? So there's a field of science called chemo-prevention which deals with how can we prevent the disease before it becomes invasive cells in the body become abnormal sometimes for triggers that we can understand like cigarette smoking sometimes for reasons that we we haven't figured out yet but there are things like vitamin D Cellini calcium in some studies have been shown to reduce the incidence of various types of cancers at least in animal models? And there are some human data to support those preventive potential effects. Anyway at this point there's not a blanket recommendation to take vitamins and supplements to prevent cancer. But we're working. Oh that's what I needed to know because you don't take any. I don't take vitamin supplements to prevent. Okay got it Terry. Tell us who is involved in. The cancer and nutrition consortium because that's what we want to learn more about. Thanks Tracy This was actually An Initiative by Dr Bruce Moskowitz. He's a founder of the effort and he really struggled with his patients that were undergoing chemotherapy and radiation therapy with nutrition and so he reached out to seven of the world's leading cancer centers to see if we could come together To conduct a research study to develop some measures to help these patients. What did the research find the research included over twelve hundred people We understand that the The largest factor of Cancer treatment is significant fatigue. Next is Constipation poor appetite Reflux indigestion just a myriad of Symptoms that really affect.

cancer Ms Terry MC Tracy This Tom Decker Lindbergh nausea methotrexate Limpopo Mayoclinic Constipation Dr Bruce Moskowitz founder partner D Cellini poor appetite Dr Paul Limburg Dr Limburg Care Team
"cancer" Discussed on Mayo Clinic Radio on Cancer

Mayo Clinic Radio on Cancer

04:01 min | 3 years ago

"cancer" Discussed on Mayo Clinic Radio on Cancer

"That's true for any screening test for colorectal cancer. Alright so use easy you Put a sample into a box have the ups guy come. Come pick it up and you're done it. And how long does it take to get the result Once it the sample gets to the lab. The turnaround is less than a week Several days. Yeah You. You put the sample in in collecting device. That's that's well said Tom. Yeah yeah no it's. It's it's from a patient standpoint. The the kit has a very simple collection device. That mounts to toilet sample is is put into the container. The LID is screwed on and it's shipped in the same container to the lab. I would imagine. Though as the case incidences of colon cancer continued to rise that their family members that say. I'm I'm all in testing where we're going to start in. They don't even care if it's color guard or colonoscopy that has to help with people's willingness to go through testing or is that not happening. Well we we looked at the first one hundred thousand color guard tests that were offered post-approval forty two percent of those patients had never been screened before and that was across all ages. That was exactly what we're hoping for And so we. We hope that having access to to attest that does not disrupt work. That doesn't require. Change in daily activities will make a difference in compliance and at the end of the day. It's participation rates that. Let's say you do a thousand tests. How many are going to end up being a positive? Yeah that's That's the positivity rate is about thirteen percent wow But many of those patients have real disease mostly polyps are common and the test detects the large polyps out of thousand patients five to seven. We'll have curable stage colon cancer without symptoms trouble stage pre-symptomatic let's say that Unfortunately it is diagnosed as being cancerous whether it's through color guard testing or a colonoscopy what Howard patients patients treated. Yeah well if it's detected at the earliest stage before symptoms some of those cancers are actually in polyps and they can be treated and discuss publicly without congressional so you read through the Columbus through the connoisseur. Yes conventional surgery. There are many approaches. They're depending on where the tumors located It doesn't in. In most cases it does not require a colostomy fewer than ten percent of patients with colorectal. Cancer require a colostomy. That's that's a myth. That's out there in. Most patients ball function is the same after surgery before and if the cancer has spread is they're usually there are other modalities involved. Chemotherapy may aviation but chemotherapy the mainstay of of of metastatic or colon cancer. That has yes. Yes and there's a lot of progress along those lines in even with metastatic cancer if if it if the spread is early and localized that can be cured also by surgery for example a solitary metastases to the liver or the lung Va. If that's all there is that can be cured with additional reception outside of the Colin boy. There's so much reason for hope but obviously the key is defined at early times it's our. It's our goal. It's our hope to see colorectalcancer. Become one of the least common cancer killers in this country and I think with accurate tools. Broadly in widely used. That's an achievable goal. Dr David Aqueous gastroenterologist colon cancer expert at the Mayo Clinic. Thanks for being with us. Thank you for the latest in health and medical news go to news network DOT Mayoclinic Dot Org..

colorectal cancer Cancer Dr David Aqueous Tom Mayo Clinic Va Columbus Howard
"cancer" Discussed on Mayo Clinic Radio on Cancer

Mayo Clinic Radio on Cancer

05:51 min | 4 years ago

"cancer" Discussed on Mayo Clinic Radio on Cancer

"Welcome back to Mayo Clinic Radio. I'm Dr Tom and I'm Tracy mccray cancer of the Cervix Tracy. There's some actually some good news about this cancer. The number of women dying of cervical cancer has decreased over sixty percent since the introduction of the cancer screening test called the PAP smear which was invented by a Greek physician. By the name of Papanicolau. I said that because my wife is. I know you're very wise points. But according to the CDC there are still twelve thousand new cases of cervical cancer and four thousand deaths due to cervical cancer every year in the United States. Now most of these are women who were either never screened or they weren't screened often enough or as often as they should or they had an abnormal test and didn't have adequate follow up. How in an effort to raise awareness about how women can protect themselves from hp the Human Papillomavirus and cervical cancer. January is cervical health awareness month here to discuss cervical cancer screening. Is Dr Kathy mcglaughlin? Dr McLaughlin is a family medicine physician. Who focuses her research on improving rates of cervical cancer screening? Welcome to the program Dr McLaughlin. Thank you nice to have you on the program so at Tracy said and she talked a as if there was a definite connection between. Hp and cervical cancer. Explain that Sir. This was a really exciting. Finding basically in science world to recognize that the cause of cervical cancer ninety nine plus percent of the time is persistent infection with human papillomavirus or HP there. What do you mean? Persistent infection will use the term. Hp Okay going forward rather than human papillomavirus It's a very common virus of the CDC estimates that about seventy to eighty percent of sexually active adults will have an infection at some time in their life. Most of them won't recognize that there won't be any clinical outcome symptom associated with it. They'll clear and be fine but in a handful of patients that high-risk HP infection persists for years and over a ten to twenty five period of time that can result in precancerous changes of the cervical. Sal Okay Gotcha subsequently cancer or so. It's a it's a virus so even if you knew you had or even if you had symptoms what would the symptoms be a and could you treat it low risk. Hpv is a separate category. That doesn't cause cancer but causes genital warts but the high risk. Hp really doesn't present with symptoms that patients would see your find and after years and years of exposure potentially that would be picked up with some cervical abnormalities on the pap test or on an HP test. It could be picked up that way as well. But they're really wouldn't be symptoms that patients would be watching for and the majority of the time the infection clears without intervention especially in healthy people with normal immune systems. How did you figure out that? Most cases of cervical cancer were were caused by a persistent. Hp infection yeah. I actually don't know how that was figured out. But there was a German virologist who was instrumental in making this discovery a number of years ago and then just through process of studying that virus figuring out that it actually is responsible for a lot of oral head and neck cancers penile anal cancers too. So it's not just women that need to be concerned about hp so what are the symptoms when someone has cervical cancer or HPV. Either one both so if somebody was not getting regular screening and came in and was diagnosis cervical cancer symptoms. They may not be irregular. Menstrual or vaginal bleeding But again most of the time especially if it's a precancerous diagnosis either. Low Greater high-grade cell changes that would not be symptomatic and that would just be picked up through the screening test If you pick this up early on a on a pap test then you can prevent it. From spreading prevent it from getting worse and basically prevent cervical cancer correct. Cervical cancer is preventable through a combination of screening and vaccination the screening itself identifying the changes the prevention pieces following along closely than if a PAP abnormality or. Hp positive test is noted. That person would be put into a surveillance program with some are frequent testing and depending on how that progress potentially have a treatment to prevent the cancer the introduction doctor shoves read a laundry list of some things but the adequate follow up after an abnormal test was surprising to me. How is that falling off of the radar right So in the old days so to speak. The recommendation was annual PAP testing and that has changed significantly in recent years. Recognizing that three or intervals with PAP tests or five year. Intervals with PAP. Hp Biko tests for women thirty over are adequate. Because it's such a slow progressing process but when people haven't come in that's how these situations can happen so screening only works if it's done on a repeat basis and so people who have not engaged regular there is that potential that the infection isn't clearing and just coming back like they're supposed to write and so they had an abnormal pap HIV test. They're giving advice on when to be seen again. And we try to work on not letting that fall through the cracks with You know Online reminders that are patient portals system. Let reminders but it still happens so I heard you say that you can prevent cervical cancer in two ways one. Catch it early before it actually turns into cancer by PAP smear but you also said the word vaccination. Yes that is really exciting so Ten years ago the human papillomavirus or HP vaccine became available in our country. It's been used another country's for longer periods of time it was initially.

cervical cancer Hp cancer Tracy mccray CDC Cervix Tracy Dr McLaughlin Dr Kathy mcglaughlin Papanicolau Mayo Clinic Radio Dr Tom United States vaginal bleeding
"cancer" Discussed on Mayo Clinic Radio on Cancer

Mayo Clinic Radio on Cancer

03:22 min | 4 years ago

"cancer" Discussed on Mayo Clinic Radio on Cancer

"That's damaging the drug that we have the most knowledge about as a drug called doxorubicin or the other name for Adriamycin and the mean risk from a cardiac standpoint with that drug is congestive heart failure. And it's a small risk but it does happen. And we have cardio oncology just here who are specialists in figuring out how to manage that when it does occur and congestive heart. Failure means that the heart just doesn't pump well enough to get the blood flowing throughout the body and one of the symptoms might be swelling of your feet and ankles exactly or difficulty breathing. Are you an exercise program? I just WanNa talk about it anymore. It's very hard for me. It really is hard for me. Actually very emotional at this moment. I. It's psychologically. It is wonderful and terrible to be in this camp so explain a little bit about the psychological ramifications of it absolutely the U. facing a potentially life threatening diagnosis is incredibly difficult. Incredibly stressful causes a lot of Distress in most of our patients and In some patients that evening gets the point of Depression. Are Psychologists and psychiatrists are incredibly helpful And I encourage all my patients. Actually if if they're willing to see someone to talk about what they're going through. Psychologically the fear of recurrence that really lasts for a long time for many. Many patients can be an ongoing problem. So it's not just during the treatment but transitioning into the survivorship fees and then and then thereafter and we need to help patients manage us as as best we can are cancer. Education Center is a fantastic resource. They have phenomenal free educational materials. Also classes So that people can kind of see. What works for them. And whether that's art therapy or music therapy or yoga. Mindfulness Meditation can access those Those resources I really never go away. Tracy mini a year. How many years? They told me to start watching for the heart effects. Eighteen to twenty years after the treatment. So I'm at twenty eight years now and psychologically you never forget it if you want to know more about the cancer survivor program at Mayo Clinic. I am so happy that you're there to help them. And we are on hundreds over one hundred stations across the country. So how can they learn more well and we are working to get more of our resources virtual? Actually we really want to be able to reach more people not just people who actually make it here to Rochester regularly but we want to get our materials online and so that's a that's in process and and working with our it group to do that Certainly anyone who's here in Rochester stopping into the Cancer Education Center is probably the best way to do that. We also have the Dan Abraham healthy living program and they have some great classes. Low cost classes that people can access. And if you're in Rochester that's A. That's a fantastic resource But but I certainly would say cancer education center which is just the lobby level. The GONDA building in Rochester. That's a wonderful place to start in. What a great program the cancer survivorship program Dr Catherine Ready Site. Thanks so much for being with us. Thank you so much for having me for the latest in health and medical news go to news network DOT Mayoclinic Dot Org..

Rochester Adriamycin Education Center Cancer Education Center doxorubicin Dr Catherine Mayo Clinic Dan Abraham Tracy
"cancer" Discussed on Mayo Clinic Radio on Cancer

Mayo Clinic Radio on Cancer

10:35 min | 4 years ago

"cancer" Discussed on Mayo Clinic Radio on Cancer

"Cancer Therapies is the director of the Melanoma Research Lab Doctors Mira Markovic. Welcome to the program. Dr Markevic thanks better. Very nice to have you Here and always nice to know when you are seeing one of our our patients because you're sort of one of the melanoma Google around here and historically Melanoma has been easily curable. Easy to treat if it's caught early but once it metastasized once it spreads elsewhere. It's been a very difficult problem Forever as as long as I can remember. Yeah you're absolutely right Tom. This is William Ostler. Even defies melanoma cancer gives cancer a bad name to father. Madison wonder reasons has been as the malignant melanoma. The the cell itself is extraordinarily evolutionary resistant to all sorts of noxious stimuli. The cell originates from essentially nerve cell origins and it involves on the skin of the body where it acts as a producer of Melanin to protect the skin from ultraviolet radiation in doing so. The cell is bred to be resistant to various noxious influences like ultraviolet radiation chemical influences from the skin and so forth thus when a cell like this becomes malignant loses its ability to be controlled by the environment for regulated growth. It becomes very difficult to treat and as you well know the last thirty years. We've had very little IF ANYTHING UNTIL FIVE YEARS. I've never heard explained that way. That's that's very interesting why it is so resistant to to treat resisted to so many things. Yes it basically you know. It has the genetic equivalent of an elephant for for inept very small package a lot of genes available to protect itself and it uses very efficient. What's the current standard? How you said until five years ago so until five years ago what was happening. So basically in our field melanoma metastatic malignant melanoma doctor said which is imminently curable disease. When caught very very early when it becomes metastatic it is essentially life ending unfortunately with for most patients up until five years ago All we really had was treatment that could barely control the pace of growth of this tumor. And we've had a treatments that unfortunately could only prolong survival. In a matter of months with average survival times. Being on the order of seven to nine months. Depending on which study really wants it had had metastasized. The survival is very limited extremely limited in what I normally unfortunately within our practice as as time as you know you would see a patient for Thanksgiving odds of seeing that patient again next Thanksgiving would be relatively low and there's been a lot of work in this field because of that the other interesting thing about melanoma metastases anywhere brain liver in ICAN even go to the bone and as you know we've seen it in the bone and the reason that we have had to operate on it sometimes in the past is because it will grow so much that it compromises the integrity of the bone worried about a fracture but the interesting thing about it is when you look at melanoma metastatic to bone. It's black just like the original tumor really. It is oh and looking at the prep for speaking with you. I come across the phrase immuno-genetic tumor saying that right correct correct. You're absolutely right. Yeah I know it's it's Kinda interesting story so back in the eighteen eighties You know when Thomas Edison was still working in his shop and you know I think Albert Einstein was in his teenage years. A guy named William Coley was a physician and hospital in New York City. The predecessor Memorial Sloan Kettering Cancer Center. Who had this ingenious idea to infect a sarcoma which is a different type of cancer with bacteria and he could demonstrate resolution of the tour that idea produced in the late one thousand nine hundred eighty s or eighteen eighties. I Apologize What what was known at the time collies toxin the first treatment by wish the harnessing of immune system could be narrowed and directed towards the cancer. This isn't the days prior to started toxic chemotherapy. Prior to what in the fifties and sixties we would refer to as the dawn of set of toxic chemotherapy. The problem is with the introduction of cytotoxic chemotherapy with the drugs that kill cancer. Melanoma re continued to be resistant and a lot of us that were devoted. A substantial part of their professional lives at joined understand and treat this disease had to really start looking at alternative options to treat That were not chemotherapy but that involved immunologic treatments the tumor as immuno-genetic because for time in Memoriam we've known the D. Museam does recognize the cancer but it cannot do anything about it and I would say the last probably fifteen years have truly been a renaissance in the field of cancer immunotherapy specifically in Melanoma metastatic melanoma management research. So what have we got now? And how does it work well we? I've got a few things I've got a few things. We said. Therapy chemotherapy. Nanomedicine start with immunotherapy so basically you know five years ago twenty eleven is sort of the watershed year. I think in our field. I think everything. In metastatic Melanoma Knowledge Prior to twenty eleven is referred to as the Jurassic period and everything since then is really knowledge new newly generated and Lee Incorporated into practice fundamentally what we have now learned is We've gotten insights as to how to regulate the body's immune system so it can overcome the ways by which the tumor protects itself from immunologic destruction in very creative ways. Some work that was originally done at the Mayo Clinic About seventeen years ago Here by now Dr Han Dong. Who's one of our colleagues so immunologic therapy in today's setting that has led to average survival times now in the two year? Mark Relative to seven to nine. Months is a big step forward. But it's still not cured if so what we're doing right now in the realm of immunotherapy is trying to understand how do the eleven hundred regulators of immune system respond in patients that are treated with a immune drug? X? And how the system the body response to that in those do well versus do poorly. And how do we take advantage of that? A lot of work within our group and others in dissecting the environment of the tumor the battlefield between the immune system into cancer also the systemic circulation blood state autoimmune system that some people lend themselves to more a greater response sooner therapy others and does not and then various Sort of moving knob says to adjust inflammation as her immunity to destroy the tumor. So basically when you talk about an immunotherapy you're you're saying that the body's immune system does recognize the fact that melanoma shouldn't be there and it's cancer and the new moon system wants to get rid of it but it can't so you're jacking up the system in a way pretty more Tom. What's interesting about. It is jacking up alone. Probably helps you with a tire but not with the cure of cancer. So what what we've learned. Is that the so if you can imagine. This is a recipe that has about eleven hundred ingredients in it and we're trying to make it taste well for a unique audience as an analogy and in doing so. Each intervention produces a counter intervention by the body's immune system probably an interestingly What we're learning recently in mechanism. Not all that different than how. The Placenta protects the baby from the mother's immune system so a multitude of different regulators protect the fetus from being rejected from the MOM's immune system. The melanoma is alive organism in many ways a parasite into the body once it becomes metastatic so it is actively co-opting the regulation of the Systemic Immune System in a way that allows it to survive. The task for us is to understand how it's doing that overcome at at the battlefield and also overcome it throughout the body where the immune cells are being made to fight it so you have increased the survival for patients with metastatic melanoma from seven to nine months to what now an average of two years and I can tell you we are Might my fellows those come to train with us. Now are very disappointed. When we don't create a complete remission patients with metastatic melanoma which six seven years ago was an impossibility and on her. So we talked about Immuno therapy chemotherapy. The World of chemotherapy is always changing. I suppose when drug companies are involved correct correct. So what's different in chemotherapy? So it's interesting about melanoma again coming from from a disease in which nothing has worked for very many years there has been a a series of almost generational expansion of people that have tried to sort of practice not And some of them have immunologists from DB -nology background and others have also been pharmacologist people that that have developed in their scientific lives into into understanding according to human genome and what that means and so since the development of the Human Genome Project Days of our awareness of the multitude into Heterogeneity of the genome that led to the Tumor Genome Atlas as as to identify mutations unique to various malignancies one of the early findings in around two thousand two thousand one that was published by the Welcome Fund was that a certain series of genes were necessary for the survival of melon sites. The normal cells and these genes were extensively. Hyperactive in the context of malignant melanoma. Are these considered the genes of the patient or the genes of the tumor. These are the genes of the tumor. The gene's cancer. If you think of cancers disease in general cancer is really a genetic disorder a disorder of mutated genes that allows the cancer cell to live in a different way relative to its normal counterpart. Does it go from me? The patient having cancer genes to the tumor having its own genetics. Absolutely so what what happens. Really so the is. What is the intervention That takes place and malignant melanoma. It is very simple answer. It's ultraviolet light. Ultraviolet light takes These cells that.

metastatic melanoma cancer Memorial Sloan Kettering Cance Tom Google Mira Markovic William Ostler Dr Markevic metastasized Madison William Coley Thomas Edison sarcoma director New York City Albert Einstein
"cancer" Discussed on Mayo Clinic Radio on Cancer

Mayo Clinic Radio on Cancer

03:37 min | 4 years ago

"cancer" Discussed on Mayo Clinic Radio on Cancer

"These patients are protect potentially susceptible to developing for example. One of the most active drugs that we use as a drug called Adriamycin in it which belongs to the class of drugs called anthocyanins which can cause significant effects on the heart down the road. Certainly some of the treatments we use can cause impaired fertility. Some of them can cause neuro cognitive effect or a skeletal effects or even propose or even predisposed to other malignancies so these are things that we try to make the patients aware of and monitor for in the both the patients and the physicians caring for them need to be aware of the significant potential for long term effects. You're the principal investigator for the Children's Oncology Group. I didn't even know about this group until we booked you as a guest. So tell me a little bit about that group. What do you do? So that children's oncology group is a cooperative group which seeks to improve curate and lessen the long term side effects as well as understand the causes of and develop better treatment modalities and Basically do everything surrounding improving the curate for children with cancer. The children's oncology group is a group of approximately. Gosh it's over two hundred institutions both in the United States and we have some Members of the C O G in other countries. Australia New Zealand Other countries other countries in the world also but mainly in the United States and Canada. We have randomized trials. We have phase two and phase one on experimental treatment drug treatment trials. We have epidemiology trials those trials looking at the causes of childhood cancer And it's just very exciting. The advances that have been made through cooperative group trials in curing so many children with cancer so given this collaboration has helped in generating funding for these trials so it funding is always an issue. There's never enough. Funding is the bottom line. Is there ways that children or the parents of these children can get the kids involved in clinical trials if they're added hospital where that's not an option? Should THEY TRAVEL? Or should they ask their physicians? Can we do this here? How does that work so in order to be involved in a clinical trial? The patient does need to be seen and treated at an institution where that clinical trial is in fact open and available and is the funding for pediatric cancer. Research hopefully growing is that growing as well. Well unfortunately the funding has been flat for a number of years now and obviously were trying to get philanthropic organizations and at the risk of omitting a few. I won't mention any but there are certainly feeling excellent philanthropic organizations but the money is certainly never enough and the funding has been unfortunately flat. And that's the reason why you have childhood cancer awareness month so we can talk about that. We've been talking about the importance of research and clinical trials in fighting childhood cancer with pediatric hematologist oncologist. Dr Karol Art. Thank you for joining us. Dr Arndt thank you for having me. Thank you for the latest in health and medical news. Go to news network DOT Mayoclinic Dot Org..

Oncology Group cancer Dr Arndt Adriamycin Dr Karol Art United States principal investigator Australia C O G Canada
"cancer" Discussed on Mayo Clinic Radio on Cancer

Mayo Clinic Radio on Cancer

10:41 min | 4 years ago

"cancer" Discussed on Mayo Clinic Radio on Cancer

"That's a big number. Although pediatric cancer deaths have declined by nearly seventy percent over the past four decades cancer remains the leading cause of death from disease among children. September is Childhood Cancer Awareness Month and here to discuss the topic is Dr Corolla. Aren't Dr Arndt is a pediatric hematologist oncologist and the principal. Investigator for Children's Oncology Group at Mayo Clinic. Welcome to the program. Dr Aren't Nice to meet you. Thank you good to be here. It's just the most terrible topic. The saddest things children getting cancer and luckily the rates seem to be declining or are they accelerating well. The rates are probably approximately the same as they've been we do. Have as part of the children's oncology group research something called Childhood Cancer Research Network which is an attempt by the cooperative. Group Children's Oncology Group to get information and create a database of every child under age twenty one diagnosed with cancer in the United States to be able to determine just that whether in fact the incidence of cancer is increasing or decreasing. You've you'll hear some times that someone was diagnosed with childhood cancer even if they're an adult. Are there specific cancers that are indeed just childhood cancers or are there are king adults diagnosed with those types of cancers? Or what makes it a childhood cancer? I guess so. Certain kinds of childhood cancer are or certain types of cancer in children are most commonly seen in children but can indeed be seen in adults for example neuroblastoma is typically thought of as a childhood cancer however adults can get neuroblastoma. It's much much rarer in adults but they can get it. Similarly there are certain tumors in particular bone tumors like OSTEO Sarcoma or Ewing Sarcoma which are commonly seen in teenagers and young adults but they can also happen when they're in their twenties or thirties so the Toronto as a as a parent of young children cancer is the last thing I'm thinking about when I when I see my kids but parents out there. What are the sort of typical signs and symptoms? That should alert them in the back of their mind that something untoward may be going on. Well there's no one particular sign or symptom that should bring up the diagnosis or thought of cancer. In contrast to adult cancers that for example appear in the breast colon or prostate childhood cancer even certain kinds of cancer can appear in lots of different areas in the body The most common form of childhood cancer is leukemia. Leukemia often presents as persistent. Fevers or power or bruising or swollen lymph nodes but sort of vague nonspecific symptoms and. That's not the first thing pediatrician thinks about. When a pediatrician sees a child with fever but unexplained fever unexplained joint pains? Make you think about that law last for a while make you think about something more serious such as cancer for bone tumors in my area of interest and expertise bone sarcomas and a lot of times? These are considered to be so called. Sports tumors because teenagers are often very active in sports. And it's perfectly normal for normal child to have an injury or a sprain or strain and I would say that if pain from a strain or a strain doesn't go away with conservative management. After a couple of weeks then you need to start thinking about more sinister in serious causes such as cancer. So I would say unexplained symptoms Or for example weight loss. Fevers night sweats lumps bumps. Those kinds of things is there because there's so many different types of cancer that there can be from top to bottom. I guess you know when it comes to children or kidney cancer you know whatever bone sarcomas like you mentioned. Is there a certain cause of cancer in children? Is it more likely to be a genetic issue so most of the time? There's really no explanation as to why a child gets cancer. It's just one of those freak random things and I often when I meet a family one of the first things. I make sure that they understand is that there's nothing they did or didn't do that. Caused their child's cancer which I think is very important in terms of genetic causes there are. There is a particular syndrome called Lee from any syndrome which is a family familial cancer syndrome which the Classic Syndrome is cancer diagnosed in two first degree. Relatives Prior to the age of forty five in those typical cancers. Typical sort of classic case is a child with Rob Demise Sarcoma whose mother might have had breast cancer diagnosed at very early age or Osteo Sarcoma and breast cancer so there are families that do have a predisposition to get cancer there are certain cancers that do show up as I mentioned. Us juicer coma grabbed my breast cancer. There are also other more rare kinds of syndromes that can predispose to childhood cancer but most childhood cancer is not considered to be genetic given the advances that we read about every day in in cancer other any new treatments on the horizon that you can talk to us about well. That's such a broad question Certainly immunotherapy is a hot topic. car T. cells for refractory. Leukemia are things that are being investigated. Probably one of the most striking advances that have been made his been immunotherapy in high. Risk Neuroblastoma So we are exploring new agents. Chemotherapy drugs but also new approaches such as immuno therapies. Why is it that children get neuroblastoma? More than adults. Probably because NEUROBLASTOMA is considered to be one of those tumors that one could call an IM- Brian all tumor which excuse me arises from so-called embryonal rests in the body that are there at the time of birth and something just goes awry and the immunology is something on the horizon. A bright spot on the horizon for children with neuroblastoma correct explained a little bit more so one of the recent studies that actually led to approval of a drug that was specifically developed for treatment of children with Neuroblastoma. There's a drug called dinner toxic map which is an antibody specifically directed against the neuroblastoma cells when given in conjunction with other drugs that stimulate the immune system. We did a randomized trial. In the children's oncology group which demonstrated that those patients treated with very aggressive therapy plus immune therapy specifically including the dente. Cab had a significantly improved survival rate an event for survival rate and better outcome than patients that did not receive dinner Tux Map. So that's very very exciting in that led to approval of that drug by the FDA this year so Dr Arndt myth or matter of fact since nineteen eighty only. Three drugs have been developed specifically for pediatric cancers. That's not very many. Is that a myth or is that a fact. That's actually fact. Wow they're the three drugs have been the dinner toxic. Mab that I mentioned previously. Which is the antibody to treat Neuroblastoma Cofer Bean which was specifically developed for treatment of recurrent childhood lymphoblastic. Leukemia and Irwin as Which is a form of disparage. Ace used to treat children with leukemia. Specifically who are allergic to the standard form. Which is e. Coli Spare Giannis. It doesn't seem like that's that's not a lot of advances in night since nineteen eighty y such a shortage of it or is it a shortage. Well the problem is that as we've mentioned earlier. Childhood cancer is relatively rare compared to cancer in adults and so it's really not on the priority of industry to develop drugs specifically for the indication of pediatric cancers. Most drugs that we use in pediatric oncology are not specifically FDA approved for treatment of a particular childhood cancer. They get approved for adult cancers first and then we use them to treat childhood cancers so we certainly have drugs they were not developed specifically for childhood cancer. Like the three drugs that we mentioned now. The the good part is that Congress passed a law a number of years ago called the best pharmaceuticals for children. Act which was an act that allows drug companies to have six months additional of exclusivity before the drug goes to market and is the the a patent is expiring allowed to be marketed by other drug companies if they do studies and children and so that was that was something that was a glimmer of hope in drug development for children that if the industry or company decides or agrees to develop the drug for children or look for childhood indication they get an additional six months of equis exclusivity so given these medications. Are they freely available or they best administered in for example cancer centers in the country? So it's important it's in the best interest of the child. I think for them to be treated at a cancer center or at a place that has access to randomized clinical trials which is really what have significantly improved the outcome of pediatric cancers over the years and to be a center..

cancer Childhood Cancer Awareness kidney cancer breast cancer neuroblastoma Oncology Group Leukemia Fevers Dr Arndt FDA Dr Corolla Investigator principal Mayo Clinic Congress United States Toronto Ewing Sarcoma Osteo Sarcoma
"cancer" Discussed on Mayo Clinic Radio on Cancer

Mayo Clinic Radio on Cancer

13:58 min | 4 years ago

"cancer" Discussed on Mayo Clinic Radio on Cancer

"Mayo Clinic Radio. Presents conversation about gynecologic cancers with gynecologist Doctor Jaime Gomez the show hosts? Are Dr Tom Shives? And Tracy McRae. This podcast was recorded on September thirteenth. Twenty sixteen. Welcome back to Mayo Clinic. Radio. I'm Dr Tom Shy. And I'm Tracy mccray Tracy the PAP test you've heard of that. Probably had fewer near day should have and that was developed by a Greek physician by the name of George Patton Nicolau. My wife is Greek. And she's going to really like me for this. So it came into use around the nineteen forties. But actually he had discovered that you could find malignant cells under the microscope. Actually in the twenties or early thirties but nobody never got credit for it. Nobody believed him. Dull around the nineteen forties when it finally came into use. And of course that test is called the PAP test or the PAP smear and is now used worldwide for the detection and the prevention of cancer of the cervix and other diseases of the female reproductive tract. What he did what he showed. Was that by gathering just a few cells from the vagina inside the vagina vaginal tract and looking at them under the microscope. You could actually tell whether or not a woman had cancer of the cervix pretty amazing breakthrough. Absolutely the PAP test changed the lives of millions of women and now researchers are working on a screening test for endometrial cancer. Also known as uterine cancer research funded by the National Cancer Institute and Mayo Clinic is developing a screening method using DNA from a Tampon for early detection and screening of endometrial cancers now unique is that DNA from Tampa. How so and and we're talking about uterine cancer as opposed to cervical cancer and the two are connected but the cervix is just the opening of the of the uterus with baby-boomer is now in the age risk category for endometrial cancer. The number of women diagnosed each year is increasing here to discuss this new minimally invasive screening method for endometrial. Cancer is the woman leading the research. Director Jamie baucom Gomez. Welcome back to the program. Dr Beckham Gomez thank you. Dr baucom Gomez Pretty Exciting stuff and truly unique tell us about this using a Tampon to diagnose endometrial uterine cancer absolutely. We're very excited about this. We've known for decades that abnormal cells from inside the uterus can be picked on picked up on PAP smears but it's not very commonly picked up that way there are other markers that are not naked That are not necessarily visible under the microscope. Such as molecular markers that we can actually now test for these are changes in DNA so DNA mutations DNA methylation which is where the gene is actually turned off because of a change to. What's kind of hanging onto the DNA called methyl groups And we can pick those Those changes up not only in the actual cells that are the cancer cells but when those cancer cells shed and flow down through the cervix into the vagina they can be picked up Those those signals can be picked up on PAP smear and we're actually taking it to the next level of Trying to pick them up on the fluid in the vaginal canal because it's in that fluid it's in that fluid and And the reason that we're focusing on detecting this using a Tampon is data. Tampon is a common hygiene product that most women use in fact The tampon business in the United States in two thousand fifteen one point five billion dollars so we know using using that as a surrogate that this is a very common while accepted collection prod collection device. It's not a special Tampon by any means the kind you just buy it the convenience store. Well we're doing from from the research standpoint we're just using the common over the counter regular about Tampon As we develop this test further a likely be something a little bit more specialized so tell us how this works a you you tell the woman To use a Tampon put a Tampon in and then take it out when and then bring it to you is that how does it work so right now. We have clinical trial open In which we are collecting Tampon samples from women who are coming in with abnormal uterine bleeding That are paramount of puzzle or postmenopausal. So it's still in the research phases And before they have a biopsy to determine whether or not there is what the cause of that admirable pleading is on. We're asking them to collect a Tampon They're doing that in the clinic. We time how long it's been in the vagina because that's also part of the test need to figure out exactly how long it It needs to be in the. What's the minimum amount of time? And then the then the Woman goes on to have her clinically indicated biopsy in. How's it doing so far Well so far we've enrolled almost a thousand patients to that to this clinical trial And we're working on the combination of markers DNA methylation mutation Markers a table a test in prospectively in those in those samples with this sounds were some somewhat similar to Coa guard where you take a stool specimen and look for abnormal DNA DNA. That will tell you whether or not the patient has colon cancer. Same principle absolutely. So guard is a combination of mutations. One mutation and Three methylated genes. And they're all they also look for fecal called Hemoglobin so much a colt hemoglobin doctor. Yep exactly so fecal a call him Gordon. They're looking for blood as well. So but it's a multi target DNA test that is self collected and exactly. That's exactly what we're trying to To do with this type of a test. is develop something that is highly patient accepted something that provides women with high access meaning. They could collect the sample at home and potentially mail it in. That's our ultimate view or ultimate vision. I should say that would make I would imagine. Make a big difference for anybody could take part in that. I mean it could be that someone notices that they're not feeling writer. They've got some symptoms but they don't end up going to see a physician. This would be a good step to get that ball rolling absolutely. We know that decreased access to healthcare Does worsen survival in certain cancers. So that's that is something that we are hoping that ultimately we impact so uterine cancer itself. What are the symptoms? Who's WHO's at risk for this particular problem? Yes so there are very well known. Risk factors for uterine cancer. Obesity is probably one of the largest risk factors for wearing fur and mutual cancer Also having diabetes hypertension Those are also hyperloop. -demia those are risk factors having a family history of Uterine Cancer Colon. Cancer Stomach Cancer Those symptoms those cancers tend to If there are families where you can actually see high numbers of those cancers and that's consider Lynch Syndrome are some families are diagnosed with Lynch Syndrome? Which is a genetic condition that puts women at higher risk for uterine cancer? You don't hear about very many women. Dying of uterine cancer. I know it happens but it must is not all that common so it must be very treatable if you can. Just make the diagnosis right. It is It is fairly treatable especially in early stages early stages typically the treatment surgery alone Even in advanced stages There are potential cures but usually it requires extensive surgery radiation and chemotherapy and the side effects of those are oftentimes long lasting. And what are some of the symptoms of endometrial cancer? Yes so symptoms. Ninety percent of women with endometrial cancer will present with some sort of abnormal bleeding or abnormal vaginal bleeding Postmenopausal women I About Even though ninety percent of women with cancer will present with abnormal vaginal bleeding. Only ten percent of women who come in with postmenopausal bleeding will actually have a cancer. Well that's a good thing. It is a good thing it is but also all of those women undergo an Mitchell biopsy which is an invasive procedure and. We're looking to try to help void that as well. It's it just as interesting just as an exciting just as incredible caller of art so We wish you all the success in the world. But now we'll expand our discussion to other reproductive system cancers because September is gynecologic cancer awareness month so Dr Gomez why Why is Ovarian Cancer? The the worst of all of these so ovarian cancer has kind of a long standing nickname. And that is that. It's the silent killer The signs and symptoms of ovarian cancer can be very vague. Despite the fact that it's already in its advanced stages the signs and symptoms of ovarian cancer typically fall into four categories or for For symptoms and that as abdominal bloating distension Change in appetite or society basically getting full fast when you eat Bowel changes Whether it's swinging constipation or diarrhea And then bladder changes Frequency a frequency of urination or urgency. So let's go over those. What's more loading Just WanNa make sure that that all of our listeners have. These bloating is one but that everybody has that at one time or another and you sort of write it off yet. We're talking about something that's constant that's persistent for. You know. Probably more like two weeks or so rather than an intermittent type of process But you're right. That's why these scientists. These symptoms are quite vague. All right and then you had bowel changes Bladder problems and a number two and I had to do with eating society full fast. So is ovarian cancer in a sense somewhat. Like cancer of the pancreas in that because the the ovaries are so deep-seated that tumor has to get fairly large before it does cause any symptoms and by that time it has often metastasized or spread elsewhere. Yeah there are different patterns As far as the spread of ovarian cancer but most often the GI type of symptoms the bowel changes and even the early Feeling full early in a meal. are probably related to the Matassa metastatic deposits that are on the surface of the small intestine large intestine and sometimes even the stomach. So what's this a five year survival rate now for women with ovarian cancer and compare that to? Let's say a decade ago. Are we better? We're better yeah. We've definitely made a lot of progress. I think it's it's hard sometimes to go through to actually dissect what the Five Year. Survival is for ovarian cancer in general because most ovarian cancers are diagnosed at an advanced stage One of the most important prognostic aspects is thorough surgery In the beginning of the diagnosis out. Good you can get it all out. That actually improves five year survival And some studies have actually shown that at five years More than fifty percent of women are still alive who were diagnosed with advanced stage disease. Where is it usually go to from the ovary it starts there? Then where does it spread? it likes to go to an organ that's inside. The abdomen called the mental It is an organ that hangs down off of the stomach and large intestine. So it surgery if you can if it's a metal to the surgery hasn't spread to too many places or too far away from the ovaries chemotherapy. And what about radiation is it? Ever part of the regimen radiation used to be part of the regimen for ovarian cancer but it has It has fallen out of favor. Because we've shown that chemotherapy is actually more effective so treatment for ovarian cancer is a combination of surgery and chemotherapy. Sometimes we give chemotherapy first and then surgery in between two courses of chemotherapy. And what's the average age of the woman diagnosed with ovarian cancer most often? The woman that segments with cancer is going to be in her early sixties so it is yes. September being gynecologic cancer awareness month. We've talked about endometrial cancer and ovarian cancer What's up next cervical while cervical cancer? Also one of our specialties. How deadly cervical cancer so cervical cancer actually the mortality in the United States as well as in other developed nations has dramatically decreased with the introduction of the PAP smear Back in the nineteen forties We also now have the vaccine against the Human Papilloma virus which causes most of most cervical cancers That vaccine or those vaccines. I should say because there's actually a series of them that are that are available those vaccines. We don't think we've seen the impact of them yet. because those are vaccines that are currently indicated for For Young Women Ages Eleven and twelve and men too and Manitou. Yup exactly if enough people love of young people get vaccinated weekend pretty much. Wipe out cervical. What percentage of cervical cancers are caused by this virus ATV? Almost all of them are caused by high risk type of virus. Seventy percent are caused by two specific viruses. Hp Sixteen at HP eighteen in the vaccine. Good against both of those. It is all three. Vaccines that are available are include. Hp Sixteen Eighteen. What's hard to believe but women can also get cancer the vagina often. Do you see that so vaginal cancer is much more rare than than cervical cancer but it is also most often caused by those same viruses the HP viruses the key of that HP. It's it really is a cancer vaccine. I think people tried to diminish it a little bit saying Oh it's a sexually transmitted disease thing but it's it really is a cancer vaccine. Yes it is all three of the vaccines that are available are against The include HP sixteen eighteen As.

Cancer Ovarian Cancer uterine cancer endometrial cancer colon cancer National Cancer Institute Dr Beckham Gomez PAP Doctor Jaime Gomez Mayo Clinic United States HP Tracy mccray Tracy Mayo Clinic Radio Dr Tom Shives Dr Tom Shy Tracy McRae Dr baucom Gomez