20 Episode results for "aspirin"

The risks and benefits of daily aspirin

Second Opinion

03:19 min | 1 year ago

The risks and benefits of daily aspirin

"This is Dr Michael Wilks. With a second opinion people are creatures of habit. Changing routines is very hard. Ask Any dentist. Who was I tried to get people to flush regularly or Dietitian who has tried to get people to avoid soda or primary care? Doctors who tried to get people to change change their lifestyle to include more exercise so it took a long time for doctors to convince throngs of men to take a daily Italy baby aspirin to prevent heart disease and stroke Peter. This week came to see me. seventy-six has high blood pressure and high cholesterol. His Dad died of a heart attack at age. Eighty two and he wants to avoid dying of a similar fate so he has taken an aspirin every morning. For far for more than a decade it causes him heartburn. What we call G. I.? Reflux symptoms so he asks how effective the aspirin is at preventing a heart attack. Well it turns out that the benefits of taking aspirin to prevent heart disease and stroke has recently been called into question after the three. Large studies were published. These studies looked at preventing heart attacks and strokes in people who had no prior history of heart disease. We call this primary prevention. The studies found that there was a benefit of aspirin on reducing nonfatal heart attacks. The aspirin sprint does not seem to reduce the risk of strokes. Well none of the studies showed the daily Aspirin reduced fatal heart attacks or death compared pair to know aspirin preventing fatal heart. Attacks is what we all hoped for by taking aspirin. Those who are taking daily aspirin are are also at higher risk of developing intestinal bleeding. Now most of this will be minor with the bleeding can be life threatening and occurs at about the same aim rate as having a major heart attack taking daily aspirin also leads to an increased rate of developing a brain bleed. So Okay Peter and I use the website. CV RISK CALCULATOR DOT COM and we estimated that Peter's ten year risk of a heart attack was about twenty the eight percent. Peter is seventy six which is an age where the treatment benefits of aspirin are very small but the risks of bleeding both in the brain and in the stomach are especially high. I Know Peter is afraid of dying of a heart attack and he seems to minimize the risk of intestinal no bleeding. Of course the decision about aspirin is Peter's to make but I would recommend. Peter stopped taking his daily aspirin but cautioned him to continue to take your blood pressure medicine and his cholesterol lowering medicine and exercise daily of course weighing risks and benefits is never easy nor is changing our routine which for Peter has included taking a daily aspirin. Every morning with his breakfast he will now need to weigh the a very small benefits of daily aspirin against the much higher risk of complications. This is Dr Michael Wilks with a second opinion.

aspirin heart disease Peter Dr Michael Wilks Reflux Italy eight percent ten year
Ep 29 Aspirin the Wonder Drug: Crossover w/ IDOP

This Podcast Will Kill You

1:24:21 hr | 2 years ago

Ep 29 Aspirin the Wonder Drug: Crossover w/ IDOP

"Buffy makes betting that is earth, friendly, and cruelty free. Their latest product, the breeze is a comforter made entirely from one hundred percent eucalyptus fiber, so regulates temperature and keeps you cool and comfortable all night, long, and Buffy offers a free trial. So if you don't love it return it at no cost for twenty dollars off your Buffy comforter, visit Buffy dot CO and enter code this podcast. That's Buffy dot CO and enter code this podcast for twenty dollars off. Hi, I'm Erin Welsh. And I'm Erin enough dyke, and I met. And this is this podcast will kill you crossover style with them defensive plants. Yes. And this week, even though are pass up associates have primarily focused on poisons. We're doing something a little bit different a little bit healthier. I mean it could be a poison if you took enough of that's true. I mean, that's that was the lesson. We learned in poisons, I guess. Yeah. But, but this week we are talking all about aspirin and in particular, willow. And some of the other plants that produce some of the primary components that are made are there used to make aspirin. Yeah. This was an exciting one because it's something that I was introduced to early on when I was starting to learn about plants and something we all kind of took advantage of shutouts my friend who started putting willow, barking tea, and then realized he was bruising early bed. There was a steep learning curve. And we figured out that this was around. So this is a this is like a hearken back to my early days of plant obsessive miss first flirtation with planes. Yeah. How fun cool. Wow. Okay. So to celebrate aspirin, we are drinking. Our current teeny named painted the aspirin. There we go. Excellent. And what is in pain in the aspirin? We've got rum lemon juice and time simple syrup. It's really delicious. Seeping it simple. Quite taste good botanical families in there. Yeah. And we will will post the recipe for this quarantine as well as non alcoholic, placebo. Rita on all of our social media pages, including Twitter teepee, w k y and Facebook and Instagram podcast will kill you and our website. This podcast will kill you dot com. So I'm really excited about the history of aspirin because it reaches back so much farther than I thought, and it also has associations or connections with a lot of other things that we have already talked about, in different areas of the podcast so be excited. All right. So this week, we're talking about aspirin, and because this is a crossover with you, Matt. We're not just talking about aspirin, but also the planet comes from, which is the willow and some of the other species of plants and let me tell you willow and humans go way, way back. In fact, they go so far back that we can't even say for certain when people started using willow bark as medicine or if it was even home associates that used it, I. Ooh. Because willow bark was actually found an Anatole burial site in Iraq dating back to sixty thousand BC, are you. So yes, yes, we can't, we don't know, for sure. Obviously people don't know, for sure. Why it was there, whether it was included intentionally or had been used for, I don't know some sort of ritualistic purpose. Or maybe it was just a random toss some, you know, things in their super cool. So what do historical texts? Tell us something called the or you are third three. I don't know tablet. I read it just it's cool. It's fun. Yeah. Urged every earth, three this tablet dates back to three thousand b c from ancient Samaria, and it includes some of the earliest known, references to willow as a treatment, and you've probably, or maybe not remember me talking about the ears Ebbers papyrus. Yes. That yeah. That medical tax from. Ancient Egypt and was written around fifteen thirty four B C. But it contained information that was much much older. So some sections had been copied from documents that were at least a thousand years older, how she's and Egyptologists have gone through the over one hundred sixty remedies listed in this papyrus to try to identify the ingredients and they really only been successful in about twenty percent of those. But one of those is willow plant that makes aspirin. It also includes another cells let producing tree in its list of remedies. The Myrtle anyway, okay did not know that. I don't know what that is. So there's a lot of it's all good. According to this papyrus, you should mix together, willow either ground up. Barker leaves figs, beer and dates, odd combination south good tasting. I drink get at think that's for a cough. And if you have muscle aches, arthritis, you were supposed to have applied willow south to the affected area, but that may not have worked depending on how much you put on yourself. But in any case, by the time that ever papyrus was written. The willow was well known as an effective treatment for various aches and pains and fevers and whatnot. And that makes it one of the oldest, if not the oldest effective plant based treatments that we know of dating back so many tens of thousands of years. This really neat. Yeah, the Nando thing, it's like it just bigs that question of how the heck did any species figure that out at some point, right? Well. And one of the things that, you know, probably. Perpetuated, its reputation as this legitimate medicine besides the fact that it actually worked was just how wide spread it was. They were all over the prehistoric world. So if you in ancient human or Hamad, trying out some new treatments for your sort toe or whatever you might have run into willow as a possible relief provider. Yeah. And it's interesting to think about where they grow today in how, you know, quote unquote weedy, they can be it's usually along some sort of riparian area Niro body of water disturbed areas places where humans would frequent and they re sprout after you cut them. So it's one of those things that would have been ever present. Yeah. Yeah. Exactly. It's like kinda make sense, but also is still blows my mind that it would be so old. So the ancient use of willow as a pain reliever has ample support throughout the ancient world. We've got Hippocrates, of course using it for an effective analgesic for childbirth. And also. Fevers and ancient Roman physicians or scholars also wrote about using it to treat pain ancient Chinese texts show that it was used as a medicine by the sixth century see it was also used by people living in southern Africa. And by native Americans before Columbus by around two hundred CE willa was basically, as common remedy as aspirin is today, but then mysteriously willow just kind of falls by the wayside in much of Europe. And it's important as a medicinal plant there, wouldn't be recognized again until the seventeen hundreds, weird. Yeah. It just kind of disappears. Okay. But what happens in the seventeen hundreds, let me set the scene? I just want to say how excited you face. For the, the drummer. Okay. So you are a fifty six year old man. A Reverend living in chipping Norton, a sizable town in England. It's the seventeen hundreds mid seventeen hundreds to be exact. It's a gorgeous day outside the sun is shining. Birds are calling. And there's a gentle breeze. Whispering through the willow trees boom on days. Like today, it's your habit to take stroll around your property navy stopping for a bit for a little sit and think, and one of your favorite places to sit and think is underneath the willow trees that lined the creek on your property today as you contemplate your next sermon. Perhaps, you absent mindedly take a piece of willow bark and pop it into your mouth. You have not truly. I. Sorry, that's exactly what an Oxfordshire accent with sound like. The bitterness of this bark is shocking, and the gears in your mind, start, turning, this bitter bark is reminding you of another medicinal plant, which is effective for treating fevers but is in super high demand, almost impossible to get any idea, what that could be. Is it that Myrtle thing you were talking about? Think outside aspirin. This is a Matt question embarrassing myself here that. Something in the carrot family. I don't know. This is something that hearkens back to first season. Teepee w k y quinine. Yep. Jonas shree. Yes. So, so the Sinche, ODA Trie, which is where we get quinine was super. It was there was a monopoly on it, basically. And you could not get it, which was really problematic, because tons of people were suffering from malaria. So there were a lot of efforts to try to find cheaper alternatives, or at least available alternatives to this in Shona tree bark. So when Reverend stone and this really happened, by the way, this whole sequence of events, I've just described when he tasted that bark. He immediately saw the potential for it as a substitute for the Shona bark, and he wanted to pursue this. So the first thing he did was he set up a bunch of, willow bark to dry and while that was drying he searched the library for any info on the willow. Bark as ineffective treatment, he didn't find anything probably because he was looking in more recent books. Control f. And been invented yet. That's funny. Fortunately, he wasn't dissuaded by this. And so he ground up his dried, willow bark and started looking around for some malaria sufferers to volunteer for treatment, and he administered the powdered bark every four hours to these volunteers in increasing doses. Until he reached one that appeared to work, the fevers disappeared word got around and his tally of cured patients grew larger so then Reverend stone sent this letter describing his discovery and subsequent experiments to the head of the Royal Society and the discovery within that letter gained traction very slowly, unfortunately, and Reverend stone died before its importance would be recognized, boomer. So while his curiosity helped to bring willow to the forefront of plant based medicine again, he wasn't entirely correct. Either though in how it worked as we discuss the malaria episode quinine, which is found in central park, actually attacks, the parasite itself that causes malaria while willow. Bark, just relieves, the symptoms doesn't actually treat the disease. Yeah, I was gonna say he didn't. Made their fees are suffering. Yeah. Well, and in some ways that made his discovery all the more important because this was a remedy that you could use to treat all kinds of aches and fevers, not just malaria. Very true. I was gonna say I mean, that's one of the most common things I hear people talking about is how the heck do people figure this stuff out. And there's a firsthand account of this tastes like this. It's gross. Let's see. Yeah. Yeah. Yeah. I think that's a really interesting. The whole it illustrates exactly how early humans might have done it to this tastes like this. That thing does this, this could be like that as well. So from, from the time that Reverend stones whose first name is Edward, by the way. From the time that Reverend stones letter published in philosophical transactions in seventeen sixty three says quite a long time ago to the early eighteen hundreds willow had started to be widely used as a cheap, alternative to sin Shona bark. And during this time the field of chemistry had really started to ramp up. So there was motivation to isolate active compounds in different remedies, so that you could do things like regulate dose, increase concentrations, and try to make synthetic version so that you could reduce the cost, it's all about the money fell about the Benjamin. Quivalent of the temporary. By nineteen twenty things like strychnine, caffeine morphine and quinine had been isolated, and it was only a matter of time before willow got the same treatment progress to isolate the active ingredient, willow bark was maiden teeny tiny increments. So I started with impure lumps or then maybe you got a few grams isolated from a kilo of bark, but eventually, the methods were refined and more could be obtained. And this is when a name was given to the substance. I Sal sin after Salix, which is the Latin name for willow and then salicylic acid. And during this time so willow is not the only plant that produces this compound to doing this time. Another apothecary chemist was working on a pet project of his own trying to isolate the active ingredient in the meadow, sweet flower, spuria spy real. Hey, set by rea-. Ol- Mara so medicine. It was thought to have pain, relieving qualities. So he decided to make a tincture, which then was used by another guy to experimentally treat to volunteers for fever and pain long story short. It was found to be effective. And this guy was like everyone listen up. I found something totally new and amazing and actually. Oh, okay. Yeah, it is just also Gasset. This is nothing new here. But it kind of did really cement also acids reputation as a pain reliever and fever reliever. So after south acid had been isolated physicians prescribed it to patients, but people didn't really love taking it. It was acid south look acids, super acidic would hurt their mouths and stomachs, and they didn't really want to take it again. So something had to give a guy named Charles Gerhardt tried to reduce the acidity of Sal silk acid by adding seal chloride. And when he did that he got out an IMP. Here in crude version of CDL, Sal silica acid, which is what is in our aspirin pills today, boom. So then Gerhardt's work was picked up by somebody else. And then this incremental progress just continued to happen. Just a couple of things remained, though before aspirin could actually become the powerhouse medicine that we see it as today. I money second justification. If someone was going to invest time and energy into synthesizing, this compound, the had to be convinced it was actually medically important, and that justification would come in eighteen seventy four in the form of pretty carefully done study on the effectiveness of Salomon entreating romantic fever. The study was published in the journal the Lancet and that seemed to be the push. That's house in needed to gain widespread and immediate recognition for the cost of south and went way, high and doctors everywhere started publishing their own findings. So this led to more wide-scale. Trials of both salads also acid and seeing what else it could do. Okay. So for the next segment of the history of aspirin will see how German die making company set the groundwork for creating the multibillion dollar pharmaceutical industry that is that it is today. This is the story of Bayer. During the eighteen hundreds when all of these different medicinal compounds were being isolated and purified and prescribed physicians would sell them by their chemical names, which were often really complicated and hard to remember. And by the late eighteen hundreds, there were just too many names to remember. So some guy had the brilliant idea it really wasn't billion idea of renaming chemical to something memorable and then patenting the production method. And this was genius because Dr could then more easily remember and spell, the name Tylenol, for instance, compared to see Dominican paracetamol or paracetamol and head this time pharmacies were legally obligated to follow a doctor's prescription to the letter. So if he had written acetaminophen, any generic acetaminophen could be given. But if he had written Tylenol only Tylenol could be given. So then these could make Bank. Yup. Tricky tricky. Yeah. And so you could see how this naming and patenting system would appeal to many of these chemical producing companies. Yeah. Many of which switched to focus solely on development and production of these medical compounds or renaming other chemicals and finding unique ways to make them. And so this is how bear which started out as a die making company found itself leading the pharmaceutical industry. But what is the actual story of aspirin, not of willow or sell silk acid but aspirin capital, a trademark? Salicylic acid was on a long list of chemicals to try to improve in on Bayer's list, and it because it had clear medical benefits and bear would really clean up if they could find a way to lessen, it's nasty side effects, but when Bayer chemist Felix Hoffmann found a way to officially make Sita sell silk acid, which didn't have the painful side effects of south silica CID, the head of development Heinrich dresser, refused to test it and clinical trials slash because he was like, oh, salicylic acid. It enfeebled the heart. And this chemical will be no different deterred. Tear. So he stopped all the work on it. And instead, he shifted his focus to diocesan morphine, aka heroin, grain, which, by the way with its trademark name. Did you know that though it was a trademarked Nate heroin? Yeah. Oh, I didn't know that. Yeah. So another guy Arthur, I can grin, who is another chemist at bear. He was not happy with the Sicilian to abandon Sita. Salik Sita select. I hate this term a sell silk acid. So he took matters into his own hands. He went behind dressers back to conduct a bunch of drug trials all of which of course for successful. The only heard a left was deciding on a name for the new drug so spire from spy, rea-, the genus name of meadow sweet as an end as a nod to seat, elation a and in just to make it easier to say. And remember, so that's how you get aspirin. I appreciate that. So much more. No. Thank you. Aspirin. The wonder drug produced by Bayer would be officially launched in eighteen ninety nine was that its tagline aspirin, the Woodruff no my tagline or missing out on the marketing good. After its launch aspirin kind of just slipped quietly onto the market and to push along recognition Bayer sent packages of aspirin to doctors all over the world, encouraging them to try it out and publish your findings and they did the drug worked. I mean, it's it is hard to overstate just how much it worked. And how many applications it seemed to have and also virtually no side effects at least at this point sales of aspirin shot through the roof and even though Germany wouldn't issue a patent for aspirin, arguing that it had been isolated before the US and Britain would. So then Bayer had his monopoly on two of the biggest markets for aspirin in the world in, even if they didn't own the rights to the patent in the rest of the world, they did own the name, which was super catchy anyway. But at the time the US medical field was very much against patent drugs, which they. Either couldn't be trusted or could be trusted, but then should be available to everyone at low cost. So it's kind of hard to imagine that, that was ever. The mindset considering how just how much has changed and things are. Yeah. Half things are today. Okay. So then bareheaded figure out how to get into the US market and firmly establish itself, so that when their brand trademark wore off, they would still be the aspirin of choice for consumers, and in a monumental law case Bayer's patent for aspirin with is deemed invalid in the UK and it seemed like things were headed in that direction for the US as well. They had until late February nineteen seventeen to cement, the brand name and image of aspirin in the minds of the public before their patent expired. So they went on the offensive. They are pushing aspirin on physicians everywhere, which, of course, the American Medical Association hated at the time and effort to reduce the sneaky advertising and promotion of drugs, that contained either no. Medicine or harmful substances like heroin and cocaine. A law was passed restricting promotion of a patent drug just the name of the company and the name of the drug. That's it. You could just say this is the name of the company. This is the name of the drug. See can't say like what it does or. Nope. Not at the time weird to stink and only non trademark drugs called by their generic names could be included in the in the official US pharmacopoeia. Oh, yeah. That's still like we only learned non-trade names, this, what's on the, the US, Emily tests, and everything, wouldn't make sense. Yeah. Yeah. All of this trademark patent advertising controversy is going down in the early nineteen hundreds and guess what happens in nineteen fourteen. Titanic note. Twelve I actually knew that the defenestration of Prague, God the dust bowl. Went once the dust bowl actually reading. Grapes of wrath. Okay. All right. Well, World War. One is what happens. And so, with this outbreak of war, citizens of the UK or like we're not supporting fair is a German company. But that was easier said than done first off large scale manufacturing of CDL sell silk acid was logistically difficult and many chemical companies had switched to making wartime things. Explosives poisons whatever. And doctors were still prescribing aspirin capital a rather than seato sell silk acid. So buyer was still making a killing, and they also were making mustard gas. So they were also making a chemical that was doing killing. Yeah. It's a sideline as we've learned. So. Yeah. So bear with so making a killing, but that was only until the British government board of trade nullified, the trademark on aspirins name, and it made it public property. Yeah. Because now it's just Aspen lower case. Yes, I never put together there. Yeah. Okay. Maybe you'll remember some other things that happened during Woodward one that are relevant to the podcast like the nineteen eighteen flu. For example. Yes. Precisely get one. Even though early rumors went around saying that Bayer made aspirin was actually responsible for spreading the flu because it was a German company. Right. But soon people got over that and were popping pills, like crazy, which, actually recent studies suggest may have actually led to excess death due to influenza, particularly in those age groups that were the hardest hit is really interesting paper on that. Yeah. So after World War One though the aspirin market became a free for all and tons of different companies began producing and packaging aspirin, which they could sell under that name finally advertising got out of control and soon. Aspirin was claimed to cure all kinds of things even if there was no evidence for them, but it was affected in a few of the claims, so namely reducing fevers pain, but ever and somehow aspirin companies had distinguished themselves above the rest, and they cope with, you know, really bizarre creative solutions, sir. Certain ones didn't nauseate some were stronger than the rest. Some had caffeine. Some had calcium. And then there was this revolutionary idea which aspirin insoluble form. Hello, alka-seltzer mornings. Oh, Don Draper. Hence it works. This was a new age for pharmaceutical advertising in many ways. All of a sudden, people are companies were taking out billboards radio ads newspaper ads and it was a free for all. And as is usually the case in things like this, the legality or regulations for this type of advertising lagged far behind the advertisements themselves. Yeah. Many of these companies were making outrageous, or at the very least exaggerated, claims and the biggest repercussions. They face for just like up slap on the wrist. That's it. Okay. During the nineteen thirties, the history of aspirin, or at least the history of bear starts, take a dark turn the company that had really established itself as a giant do aspirin had survived. World War One despite losing its trademarks and patent rights in many countries. And in the late nineteen twenties, the head of bear Carl Duisberg on high last name teamed up with a bunch of other German pharmaceutical. And chemical manufacturers to basically create a monopoly over the drug market. Cool. Great guys, it would be known as I G Farben, and it would play a pivotal role in Rover to war, and genocide are expensive. And that money has to come from somewhere. So when in February of nineteen thirty three Hitler demanded financial support from this new monopoly, and they gave it to him. In fact, I G Farben would essentially bankroll the entire Nazi party, providing an endless source of wealth to fund the war, and hall cost not know that yet. So if Bayer had not been the one to produce aspirin. It's possible that the company would have stayed in the chemical dye business. Never growing to the point where it could almost single-handedly support the Nazis. That's a terrible. What if right? Hit. Hit. And of course, it didn't just support the Nazis. But also became directly involved, starting with the area's -ation of its workforce and ending with the production of the cyclone b gas used in the gas chambers and concentration camps. And also directly financing and managing some of those camps. Let's despicable. It also financed, the human experiments conducted by Nazi doctors and scientists that resulted in death and torture for thousands and thousands of people Jesus Christ. Yeah. Even the developer of CDL sell silk acid at Bayer. So Arthur Aiken grins of this is the guy who was like, no, we're not gonna toss this drug aside. We wanna keep working on this. Yeah, he was Jewish, and he noticed that he had begun to be written out of history. His name was start has was erased from the different history books at Bayer, and not just for aspirin for many of the chemicals that he isolated as well. And also he was sent to. Concentration camp. So he miraculously survived and few years after his release. He published a work on the history of aspirin where he said, actually, I was very crucial for the drugs development and yet his role in the history of aspirin would be ignored for over fifty years to the early two thousands. Okay. So at the end actually of World War, Two twenty three senior executives from itchy Farben would be tried at the Nuremberg, trials and thirteen would be acquitted. Wow. Yeah. Okay, so far been didn't survived the war intact. But Bayer did and continued to produce aspirin at high rates after Woodward to the aspirin market had continued to grow and many other brands had taken, big chunks of Bayer's prophets. They headed up with something else. Not just another way to package or advertise. Aspirin something else entirely. They went back through their development records and found a chemical by the name of n acetyl para a minute, phenyle, which appeared to be an analgesic. But with some nasty side effects so they revisited as chemical, which they called a CD benefit. Oh, yeah. And didn't find any of the side effects that it had that had halted its earlier development. Boom new drug created perfect done. I had no idea that they are also made Tylenol they call it Panadol. So this was they called it acetaminophen. And then in the UK it became known as paracetamol and it. It's brand name was Panadol. And so it was like it's flew off the shelves because this was this non stomach irritating aspirin alternative and aspirin kind of just started to slip out of the leading place in the market. And in the US say Dominican, of course, would be Tylenol, and I pro- Finn was not far behind. And so, by the nineteen sixties, the trio of aspirin acetaminophen slash paracetamol an IB pro fin dominated the over the counter analgesic market and aspirin continued to slip until the nineteen eighties. And it took a major blow when the link between aspirin and raise syndrome was discovered. So just when things were looking pretty grim for aspirin its renaissance would begin. Who all of this history of aspirin that I've talked about so far? There's a lot of history there. Sorry about that. Its mechanism of action was still unknown, though a new how it works. Yeah. It's funny because there wasn't much interest in finding out the mechanism of action and till nineteen Fifty-eight when a dude, a chemist name, Henry Collier, decided to play around with it, and over the next decade or so Collier, along with pharmacologists Priscilla piper in John vane. They worked together sometimes separately, sometimes on the same project to uncover the mysteries of aspirin, and I'm not gonna go into the whole thing. But essentially, what happened is that John vane made the final leap, and he and piper would publish the results in nature, where it became one of the most cited papers of all time, Cuong, vein one, a noble or was awarded a Nobel prize for his work, pharmacology understanding, the three main effects of aspirin, so pain reduction. Inflammation reduction, and reducing the ability of, of blood to clot did more than just solve a scientific mystery. It also held huge implications for the uses of aspirin, one of these being that in small doses. Aspirin had this affect on the bodies causing ability. So in the second half of the twentieth century, and through today, of course, heart disease is a leading cause of death in many industrialized countries such as the US in parts of Europe. And this anti Cottingham ability of aspirin also meant it could be used as a possible, heart attack preventative and despite many successful trials. This idea was slow to gain traction, but by the mid nineteen eighties, it was finally accepted, which meant new branding and campaigning. In the marketers back to the whole aspirin advertising situation. But this is really where my story of aspirin leaves off and where I think you pick it up Aaron. So tell me, how does aspirin work? And what is it good? Is it bad? What does it do for you? Let's talk about it. We'll take a quick break. I two piece. Oh, bed. Are you looking for your next Benjamin? Listen crooked media. The company behind pod. Save America has a new podcast this land. 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So your body actually breaks down and metabolize it to produce south Illich acid, but sat sell listen itself is what's called a pro drug meaning by itself. It doesn't have any mechanism really. But in your body, you metabolize it into south Gasset south Illich acid, as you heard from Aaron, I'm not gonna talk a ton about because it's not the interesting part of the story, it is still used today from suitably. It's in a lot of skin care products. Yeah. I've used it. Yeah. I use it every night. Another think about a C show up on. Labels a lot. Yeah. Yeah. So it's a really common acid that still used in skincare products acne products, things like that. But to take it for its anti-inflammatory properties. Like you mentioned has a lot of side effects, especially really bad gastrointestinal side effects. So the development of aspirin, a seato, south silica acid was massive because it has much less of the side effects. So how do these things actually work? It turns out all of south acid, and acetyl, silica acid have basically the same mechanism of action. But before we can talk about that we have to. I talk about inflammation your immune system has mechanisms by which it stimulates inflammation, and even though we usually think of inflammation is something bad. It's actually a really important part of the healing process. So if you imagine, for example, that you get tear in your muscle. That tear is damaged to actual muscle cells. Right. So your body has to have a way to jump into gear to repair that tear and to fix or make new muscle cells. So the way that it does that is via inflammation, your cells released, a number of different compounds that signal to other cells, like, hey, we've got like some messed up muscle cells over here. We need we need to fix this. And the whatever sales are needed can come to the aid, and actually stop the bleeding or fight off infection or whatever needs to get done cool. Yeah. So this is like, really fun. Just like general pathology that everyone gets to learn today. There are four main components of inflammation, redness, swelling, heat and pain. Okay. Yep. So few magin a cut, you can imagine that all of those things will happen. If you get a cut, you'll get redness around the cut, you'll get swelling because you're getting fluid and stuff that's coming to their it might be warm to the touch, and it hurts. It's just like when I cut my finger, when I was doing your Nikes nineteen. Choose. Yeah. Choose. And it turns out that there's kind of one main pathway by which your body actually makes a lot of the molecules that are involved in this inflammatory response. So if we can block this one main pathway, or even just one part of this main pathway, we can reduce inflammation, substantially okay, because although inflammation is a normal response. It sometimes can get out of control. Right. Right. But how so where is that line? That's a great question. And it's totally not clear. So like if you tear muscle like doing playing soccer or something like that. It's actually not clear that taking anti inflammatories has an actual benefit, because, in that case inflammation is needed to actually repair that muscle tear, right? But then at what point is there, too much inflammation, which is actually inhibiting the process of, of repair. We don't in medicine have a very good answer to that. If you have a fever. That's very, very high. Right. Like hundred four hundred five you definitely need something to bring that fever down, because your brain is gonna start to melt. Can I can I put an plug for a book really quick yet called why we get sick? Oh, yeah. And yeah, that's one of the chapters, they talked about inflammation response. And when it don't talk about one is too much. But they do talk about sort of the acts of anti inflammatories and help might be counterproductive to the healing process. Yeah, yeah. It's a really interesting, like we, there's a lot of drugs on the market to counteract the inflammatory response. And yet this inflammatory sponsors also entirely necessary to fight off infection and to. Yeah, fever, and as a kid, my mom would be like, I'm not giving it to yet you got to fight this for a little bit. She was actually doing probably a little bit of round. Good. I mean, within reason the thing is we as humans and as, as other other animals have we've evolved these responses to pay to infection to injury. And so it's kind of interesting to say, like when do we start stopping these responses and? Is that actually productive? Yes. Yeah. It's a great question Darwinian medicine. So that main inflammatory pathway is called the Iraq onic acid pathway. We've been it's good. It's a good name. Sounds fancy so a racket onic acid is actually made from its made from phospholipids that are in your cell membrane, so you can make it in pretty much everywhere, pretty much almost every sale, you can make a racket on acid, which can then be used to make a whole host of different markers of inflammation. And there are two main enzymes that break down Iraq, Donald acid into all of these active metabolites cycle, journeys, or Cox and lie talk Sinise. Which I don't think we ever short law. Flock, the old Cox in law. Okay. So everyone's still with me get. All right. So I'm actually not gonna talk about locks lightboxes, genie's. Get rid of that. We're going to ignore that, for now because it's not that important in the story of aspirin, so as it turns out cycle, oxygenates or Cox of which, there are several different forms of this enzyme can turn a racket onic acid into a number of different compounds prostate gland ins, which there's a whole bunch of different prostates and Thrum, boxing's prostate Linden's are molecules that are really imported in mediating, a lot of different parts of the inflammatory response redness, which prosecute and can help with Vasil dilation, which we have talked a lot about visor dilation in other diseases, causing redness and rashes fever, which is also via visa. Elation and pain. So there are gland that actually sent to ties your nerve cells to pain civil now you feel pain. Whoa. Pretty cool. So those are prosecuted, those are all made via a Cox enzyme from Iraq on a gas ID. You can also with other Cox enzymes make thrown boxing's. The word thrombosis means clot, and thrombosis. Right. Is a platelet platelets are the blood cells, in your body that are responsible largely for clotting you need to have platelets in order for when you get cut to not bleed out everywhere. Right. Thanks platelets. Thank you. You should think your platelets. So one, thrown box ain't especially thrown boxing, eight to it is produced by activated platelets via Cox from Iraq, Donald acid, and what it does is it helps to aggregate, other platelets, and activate more platelets to actually form a clot. So the more thrown box, you have the more clotting that you're gonna get the less thrown boxing. You have the less clotting. You're gonna get sound good. Excellent thrown boxing's are also important invasive constriction 'cause you can imagine if you're bleeding out if you can constrict blood vessels. Even if you can't clot them all the way if they're smaller less blood is flowing to that area. Okay. Make sense. Okay. So where do all of these Dallas affiliate salicylic acid SEO salicylic acid, where do these fit in it? Turns out there mechanism is to. Inhibit. Cyclo oxygenates. Oh, Scott MU so what that means is that aspirin binds to the Cox enzyme and blocks the action of it. So you cannot form Thrum box aides, or prostate Linden's from Iraq, aghast, did therefore, you have less inflammation, if you have less prostates, and you have less clotting, if you have less thrones. I. Makes sense. Gets better. I just like being able to draw the line between the dots. Clearly. Oh, okay. Yeah. Okay. So like you said, Aaron aspirin is well, say this, exactly. But I'm gonna gifts. Keep going on, on what you. They're three big drugs that we think about when you think about over the counter pain, relievers, Tylenol, or see Dominican ibuprofen. Aspirin, these are drugs that we call incense, although Tylenol is kind of not really an incid. We'll talk about it and said means non steroidal anti inflammatory that just means that it can reduce inflammation. But it's not a steroids. Yeah. Yeah. Which is cream thing, right? Yeah. So the mechanism of action of AIBA pro Finn is very similar to aspirin. It also blocks. Cox Cox box. That was funny ahead to be done. But the reason why you may have heard of doctors recommending that you take aspirin and not ibuprofen to prevent something like heart disease is because aspirin binds irreversibly to the Cox enzyme really. So what that means is that if you have for example, a platelet once aspirin, binds to the Cox in that platelet for the life of that platelet, it will not be activated and it will not form a clot. Wow. So okay question. First of all why how, how does it bind irreversibly in wide IB profit, not so either proven binds in a different place? And it just it binds reversible so it can be out competed, and it can fall off. Essentially. Okay. So I'm not a biochemist. So that's the most detail I can give you but aspirin, binds, and doesn't let go binds really tightly, and it completely blocks the action of cyclops Sinise. How long does it platelet live eight to nine days? So. Thirty years later, so. Yeah, still baby aspirin, which is just a low dose of aspirin for a while. Like you were saying in the eighties nineties, even early two thousands. It was like everybody take baby aspirin every day. It'll reduce your risk of heart attack. It's not recommended that everybody take it. However, in some people who have had previous M I or myocardial infarction it. They do recommend that those people take it because it does reduce your risk of further clot formation. And it also reduces overall inflammation, and it does so irreversibly. So you would have to take a ton more IB pro fin you'd have to take profit like every four hours because it wears off. Whereas Aspen, you can take just eighty one milligrams once a day and that's going to bind up any play. Blitz that are not yet, bound to aspirin awesome. That's crew. That's really read. It's really. Very few things that I remember from, like, original BioChem in this is one of them because I think it is just so. So fascinating. Oh, I love it. So that's how it works. You have aspirin that binds irreversibly to Cox, it blocks the activation of platelets. It does. So for the whole life of that platelet, if you don't have activated platelets, you don't have clot formation. If you don't have clot formation. You don't ACLU your arteries, if you don't include your arteries. You don't have a heart attack bloom. Simple one two, three four. I don't know how many steps there were there was a lot. I understood it matters a lot for any medical texter. Yeah. So I've been pro Finn which is another and said, it's another non-steroidal anti-inflammatory it works very similarly. But again, it is reversible. So it's not gonna have that same long lasting effects Tylenol, or acetaminophen or paracetamol as a millionaire. Is not quite the same it actually it's not entirely clear, yet, how Tylenol really works. We think that it binds Cox. But it does not do so in your peripheral body, but it might do so in your brain. So Tylenol isn't technically an anti inflammatory. It does not have anti inflammatory properties. It does have analgesic properties. So it will it will reduce pain, because it works on your nervous system, and it will reduce fever. So it's what we call an anti Rettig. Okay. So really quickly I guess we can just talk about. Like when you would actually use aspirin. I don't know. Do you wanna talk about that? Yeah. So, like I said, there is some evidence that for certain populations aspirin in small doses can be used to lower the risk of future, a myocardial, infarction, or heart disease. There's also some evidence that it can be effective in lowering the risk of some cancers, especially colorectal cancer. And this has to do not so much with its effects on clotting and throw boxing's, but on its inflammatory anti inflammatory effects because number of cancers processes were sort of learning this more and more are associated with prolonged inflammation. So if you think of something like something, like all sort of colitis which is a very high risk for colorectal cancer is an infla-. Matori bowel disease, singing, have constant inflammation in the colon and that puts you at risk for developing cancer. If you can reduce the inflammation, you can potentially reduce the risk of cancer. That's the thought. So does that go back to what you had told me a couple of weekends back, where anytime you get a situation where sales are constantly being asked to replenish themselves. You always run the risk of irregularities in cell division in this cancer. Exactly. Mind blown. Now, I also want to say I'm gonna give you two disclaimers. Number one, baby. Aspirin is called baby aspirin because it's eighty one milligrams of dose, rather than three hundred twenty five which is like grown have aspirin regular aspirin like aspirin. You take a headache. The adult aspirin. It does not mean that you should give baby aspirin to baby. Because. Bad naming. It's a terrible name for some reason, and it's not clear. Why this happens if you give aspirin to children under basically under teenagers? It can cause a very, very serious disease called Raya syndrome, which you mentioned Erin, which can lead to encephalopathy, which is swelling of in brain liver, failure, and death. It's not clear. Why this happens? But that's why in general, the recommendation is never ever give children aspirin, if they have a fever, you give them, Tylenol or maybe Motrin, which is proven. Oh, so thought explains the Tylenol okay that my childhood makes a little bit more. My mom was listening. Don't give babies aspirin. Thanks, mom. And the other caveat that I want to make is that the evidence of the effectiveness of long-term aspirin treatments is still quite mixed. It's not clear that every single human is gonna benefit, and it is absolutely not the recommendation that every adult needs to be taking baby. Aspirin, so to be clear. I am not yet a doctor who can make those kinds of recommendations. So I am not suggesting that everyone go out and start taking a baby aspirin. But some people who have certain risk factors might benefit from talking to doctors to figure out because it is very cool. It's very cool drug and for a lot of people it really does work. So so do your homework tuck to a doctor. So yeah, that's the that's the mechanism of Aspen. Isn't it? Good. Yeah. That's not expecting to understand it. And I do you have no idea. Sticks is an online personal styling service that finds into livers. Clothes shoes, accessories to fit your body budget and lifestyle. 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So when you me and said, hey, can we do this instead of what we were planning for a future episode. No spoilers, I was like, sure. And then I googled it and I was like, oh, yeah, we definitely have to do this, because my job with these crossovers usually sitting here and going well, plants don't want anything to eat them. They wanna kill you for trying or hurting really bad. And this time it's going to be really different. So we've unlocked, or at least for me, unlocked, a whole new world with the big caveat, obviously, that I'm not a plant pathologist. I do not understand genetics to any serious degree. So I apologize if fend anyone right out of the gates, but we'll do this as best we can salicylic acid implants is fascinating, because it has sort of multi purposes, it does get involved in defense, but not in the context of what we've talked about in the past with keeping urban wars at bay. It's more about defense against a bad expression to environmental stresses like drought heavy metal tolerance heat and as Motic stress, as well as some pathogen. So it does defend against bad things, but not in the context of like a deer or a Caterpillar, it's more about viruses in different things that can get in, and fungi that can infect a plant in 'cause a lot of damage. That's so cool because. Like the way humans ideals aspirin. Yes. Exactly. And the overlaps here, kind of gave me boost bumps because we often treat them a are two walks of life is so radically alien in foreign, but were a jumble of cells each with their own sort of functions. And the deeper, I dug the more the similarities started to get kind of Erie with mighty Conrad stuff, which I don't fully understand. But then there's the other side of it the hormone side where it's involved in a lot of regulation of different processes from flowering to senescence. Yeah, we'll get there. But this was a really interesting dive, and it get made my job so much cooler, this time around than to just say, yeah. They don't wanna get eaten. But the, the amazing thing is, I'd always associated with willa. Like I said it was one of the first times, I learn about, like, what was going on with plant chemistry and how that's been co-opted by humans. And you mentioned the bitter taste and I have a really funny pictures of my friend, Steve chewing on willow branches after we learn this just making an awful face, but it's found in different levels in a wide variety of plant species. This is something that plants are dealing with quite a bit. And it might have something to do with the, the defense response, and some of the regulatory functions. But the levels is what's most interesting is they found upwards of a hundred fold difference in what's produced not only among organs within plants, but among different plants. I don't know. I tried really hard to figure out why willow especially could have just been that we are closely associated with willows. They have deep historical ties to our society and our cultures or just could be that they're producing a lot more of it. I don't know. So if anyone does. No, please let me know because I would really like to know that. But it has been recognized as sort of the signal mediating plant response to stresses, but also sort of a regulatory function from hormone standpoint. So it's, it's a fanatic compound. I do think that even though you get it as salads in plants will turn it into salicylic acid. I just don't know if that involves any sort of extraction, but from the defense side of things there's a lot of papers on this in, what's fascinating is what we know about. Salicylic acid implants is still largely up in the air. There's a lot of unknowns. But we know it from studying mostly economic important species. So tobacco comes up a lot in this research, as well as rabid ops, which is the model plant system for understanding like jeans and stuff like that. So it's, it's there it's an a lot of different things, but one of the main functions in defenses that it's regulating like local disease, resistance mechanisms, and also, like assist acquired resistance, or the essay, our response. And there's a lot of pathways involved in this, I'm only going to mention a few of them. But what ends up happening is that it helps recognize invading pathogen, and then it mounts effective defensive response, which is split between sort of this cognitive pathogen encoded effector protein, which is essentially unaffected tributed ineffective triggered immunity, which then leads into what they call a hyper sensitive response. And if you've ever seen a leaf that looks really blotchy with a lot of narcotic tissue on it. You're seeing the hypersensitive response in action. So a few plant heights. Yeah. Plant hives, but think about plants as sort of these compartmental organisms, they're not like us with a low. I mean they are connected, but they're modular, you can break off pieces in plants oftentimes with their immune response when isolated just by knocking out that entire section of their tissue. Just kill it off. It's gone, and there's evidence that it's this comes into play here. So after some sort of infection is detected a few hours after even. The unoccupied portions of the plant will also sort of start to take up increased levels of the genes that start this systematic acquired resistance python. So that's more of the long lasting thing. So there's both timeframes getting involved here in immediate response, where they start killing off and trying to localize it. And then okay, we have to protect the rest of the tissues, and this is were sell silica Gasset comes into play. Yeah. So the biggest evidence that we have for its role really comes from studying plants that are deficient in these genes ability to produce it. So it's the mutants that tell us really what's going on. But it's signaling component involved in this. And so it accumulates in high levels around the sites of infection, but then after a decent amount of time it varies from species to species, you'll see it starting to turn up an uninfected systemic tissues. So they have discovered that even by inoculating the plant, or applying it with aspirin, essentially, the powdered up put it in there in some form, they can actually get those genes to start playing a role and turn those on in the plant. So they know it's signaling. They know there's something about this that saying, hey, we, we have an issue, here, we have to get going. And then the best part is doesn't end there. It gets even crazier as you go on. So after pathogen infection there's a big component of reactive oxygen. Species in here and that is really fascinating because as we'll learn later and some of the other functions of salicylic acid the relationship between these two things is extremely complicated. So what they're finding is that the relationship between salicylic acid and cell death and h two twos at peroxide, and peroxide has led to this idea that, that offenses are regulated by some sort of oxidative cell death loop, which is pretty strange to think about. But what ends up happening is peroxide, increases following, there's some sort of infection and then it activates salicylic acid, synthesis. So they, they have peroxide sitting in the cells, and that says, okay, we have to start making salicylic acid. So then as Celtic S it starts to increase they begin to work with these reactive oxygen species, that are generated during a second phase of the cell, death response, and that potentially it's more peroxide production and then that intern excavates. The synthesis of Morris, sell silica acid and cell death. And then it just becomes this self amplifying my God. This is very similar to how neutral fills kill bacteria in our bodies. Really? Yes. So the immune response despite being a modular system is there's a lot of over over laugh. Yeah. That's bizarre. So cool. Yeah, so they think it's broad spectrum this isn't specific, although the tobacco mosaic virus probably has allowed us to understand it in its most intense form. So all of this taken together, supports the sort of this contention hypothesis that sell acidic acid may be a signal that translates from the infection site to other areas of the plant. However, there's also plenty of lines of evidence mixed in there that I don't fully understand that. It's not a long distance signal so really what we can say at this point is that either salicylic acid is not a long distance signal or that all it takes is very small amounts of it within the. Infected leaves to kind of put in this systematic sort of response induction, within the plant sits, unless like salicylic acid in plants is acting the way that prostate gland ins do in humans to like go around and tell other parts of the plant, like, hey, we've got an infection over here. Right. And again, the mechanisms by which that's working, they don't know. But it is there something going on there with when that is perceived in the plant, it's, it's immune systems are kicking on cool and what's even cooler is that I didn't get into the weeds with this. But there is a way that this, this becomes volatile is, but in the form of methyl, solicit, and it, which is volatile Astor, which means it comes airborne, and that can actually signal neighboring plants to kick in with the same response without having experienced the virulent pathogens, stop at. Yeah. Which is that's bonkers. And it's one of those things that were really only now starting to appreciate. Is that these aren't static organism sitting there? I don't think this is all true ISM at work. I just think it's if you can detect some sort of signal in your environment that maybe not everything's okay, you're probably better off in the long run. Yeah. Or maybe you could recruit help or something. Yeah. Exactly. That, that's a whole new realm of, of understanding in the world of what plants are doing. Especially to one another gossiping about. It's just like the happening guys. If we can bring that up every time I'm around I'd be really happy. John leguizamo. But outside of the defense and dealing with these sorts of things. There's a lot of evidence that this functions as a hormone in regulating processes such as C, germination, vegetative, growth, photosynthesis respiration, Thermo Genesis, which is the production of heat, but she didn't plans could do that flower formation. See production, senescence and a type of cell death that is not associated with the hypersensitive response. This is a super important compound in plants trying to think of a single hormone in humans that can do that many things and chronologies let us now these affects are probably more indirectly think because salicylic acid alters the synthesis of other signaling hormones and other important hormones like jazz, Monica acid ethylene an oxen so to start with C germination, this is one of those things where the dose varies. So they found that when low doses of south silica acid have been applied to a rabbit op secedes. It promotes the synthesis of proteins, and enzymes that are essential for germination and mobilization or degradation of c proteins accumulated during seed maturation. So basically gets rid of the proteins that tell us to not germinate and it helps turn the genes on that say, let's start getting this game. Let's let's get the show on the but then there's also evidence that in higher doses. It actually shuts that down and says, don't Germany here, which actually could come into play there, and that they're not so sure of why, but it could be that have something to do with that whole oxidative stress issue there. Yeah. It also is involved in photosynthesis, which is arguably the most important reaction on the planets. The plate biologist. But also. Yeah. But one of the cooler things in photosynthesis is that what they found is that it's really important in the plant, when it's protecting photosynthesis against a specific type of urbicide, which steals electrons from the photo system pathways dares. And so it gets hair. There's an herbicides that steals electrons. Yeah. There's an electron stealing herbicides. Is that it's catchphrase? I still Electra. I hope so. Use of this urbicide seeing how salicylic acid turns on to protect the plant against this urbicide also gave us insights into, what's the actual biological evolutionary function of this could be going on within the leaf itself? That's wild. And that's all about deductive fighting those reactive oxygen species. Yeah. Yeah. Pretty bonkers. It can also induce Stu motto closure, which is again, goes back to sort of that defense against drought stress so STA Mata our pores, on the surface of the leaves, and stems that regulate the passage of CO two in oxygen inside and outside, but also water, and as you can imagine if things are getting really hot plants are gonna wanna shut those so they don't lose water. But then again, they can't keep gas exchange going on in there for can't photo synthesize know most of the money going into this research is figuring out how to make better crops, that can deal with the stressors of climate change. Mostly drought in this context. So Celso cast is being studied to an intense degree install model closure which again just for the listeners to follow that path. They so decide. So in growth plants, gotta grow right? It's little studied compared to the other hormones because the other hormones, as we mentioned are having a more direct effect, but sell civic acid is having interactions with those, so there's growth, stimulating effects that have been found in soybean in camomile, which it's interesting that came a meal thrown into the mix there, but they found it to enhance cell division. And they think this might be related indirectly through changes in hormonal status by the improvement of photosynthesis, photosynthesis, transpiration, insta- model conducted. So some of the stuff we already just talked about is coming into play when plants are starting to actively divide in grow. Now, here's things get super interesting at least for me because, flowering, it least in angiosperms, flowering plants is one of the most vital things to any sort of sexual organism or sexually reproducing, organisms. And we've known about this, actually for a very long time because salicylic acid has been shown to promote flower, bud formation in Callus tissue. So not even where flower buds are supposed to form when they Nick tobacco plant in create this Callus tissue. If you apply southville attitude, you can actually get flower buds to form, which is weird, but that tells you that something really important is going on there. Yes. I have a question. Okay. That's usually you're lying. Are there? There are plants that do not produce silica acid probably like it seems like it's kind of a big deal if all the parts of plant, I would assume that the levels are there in some sort of background amount. But the fact that it's involved in all of these things are telling me that every plant is probably dealing with it on some level. That's so weird. But think about it from the perspective of researcher, are you going to get funding for a plant that has some sort of economic importance to humanity or some obscure little, we'd sitting in a ditch or along the trail somewhere in the woods? So the unknowns here, vastly outweigh, the knowns. And so thinking about the ways that we've discovered Celis like acid to work in just important species in mutant varieties. There's probably a myriad, laundry laundry, lists of different things that could be going on other plan. And I'm gonna talk about one of those right now because this was the most mind blowing to me if I said, sorrel made them Gustad to what would that would that elicit silly? Yeah. Got nothing. That's what I was hoping for just a little chuckle. That's a giant era called the voodoo lily. And if you think of the titan Arum that gets a lot of press that giant smelly corpse flower that blooms every once in a while, it's one of those, it's close relative of those one of the most amazing things about this family of plants is that they are Thermo genyk. They produce their own heat that cell, in fact, there's a philodendron species that does this to a degree that it's met metabolic process during that is comparable to that of a hummingbird, which has the highest metabolic activity of any vertebrate animal why it's so it is converged on a similar strategy what same similar metabolic processes at least to that of a hummingbird to produce heat. And it's giant influence. Are they producing heat to see more like an actual dead body? There's elements of that. But part of that core element is the smell in what they think with the heat part of it is that had volunteered. Volatile is, is that sent in makes it spread a lot further than it would otherwise. Yeah. Cool. And then more temperate species. There's also the element of attracting pollinators. So right now, as we're recording this, it's early March and it's cold outside called heck but plans like skunk cabbage, which is a cousin of this are emerging. They produce heat which helps get their sent out, but it also is believed to attract pollinators. So what few insects are able to emerge at this time one to nice warm place to sit in stay. Why not a hot in florescent? That is so cool. Yeah. So when they studied the voodoo lily, which you can actually purchase one of these plants that are pretty common house plant, you probably don't want it hanging around in your house when it comes time to bloom, unless you are weird like me. But when they looked at this, they found that, right? As the, the, the influence is emerging in starting to produce its heat. They found about a hundred fold increase in salicylic acid rate as the onset of the heat process starts within the organ called the Spade, which is a very phallic central terminal like length of tissue or the flowers are arranged around, but tissue, yes. And so what salicylic acid does it stimulates Thermo Genesis primarily by increasing the activity of the alternative respiratory pathway within the MIDA Qendra of the plant. So switches from a plant metabolism to something way, more like an animal metabolise, Mike. So cool. Yeah, got it. And so it enhances the capacity of this alternative respiratory pathway by inducing, the expression of alternative. Oxidise. Just be terminal, electronic sceptre of the turn of the alternative respiratory pathway. So here we're seeing, again, you're doing something that's going to create a lot of reactive oxygen stuff, and why not coopt the organ of the hormone that's already they're already being produced. And that's what's fascinating to me about plants and just Evelyn in general, as you see, it's not Denault votes, not these new things happening. It's a retooling of systems that are already in place. It's, it's inducing these oxygenates enzymes, and then you put it into humans. Now, it's blocking these oxygenates enzymes, all my God to function is just mind. Blowing to me, I think it lends to a lot of the confusion in the contradictory results. We studied this one pathway, we got this and we studied another and it's doing the exact opposite. Well, it's both both. And, and how plants are doing this opens that whole new set of questions as to what is going on with signaling and sort of the mainframe of a plant. How do they regulate this without a central nervous system per se fascinating? That is so cool. So to wrap this all up. We'll talk about senescence, which is essentially the programmed reduction or death of the plant you see this more temperate species, or if you live in the tropics anytime there's the the dry season comes around, senescence is the dying back of tissues, and you don't just kill the tissue. You do it in a way in which you could probably extract some of what you invested in this. So it's involved in the. Decline in photosynthetic activity, which is also characterized by an increase in reactive in those reactive oxygen species due to a loss in the antioxidant capacity of the leaf at that time. So you have a dieback of the photosynthetic machinery, but you also are taking away antioxidant pigments at the same time, which would normally protect against those. So it's like, okay, we need to do this. It's, it's almost like the, the crossing guard, a lot of crap is going on, but salicylic acid seems to be there to say, we're not gonna let the by products of this process damage us in any way. That's so cool. Boom. But so this was a whole new adventure for me. And again, I apologize. I'm not a plant pathologist. I'm not a geneticist if I butchered any of this, the point is that. Defense comes in many forms. And in this case, it's environmental stressors. It's pathogens it's not herbivore outright. You know, this isn't something, you'd wanna go and poison someone with or could poison someone with. Although we learned yet Ken, but it's also a really important plant hormone in regulating, some of the most essential arguably the most essential processes within plants itself. Yeah. This was much more massive. I think than I think we all realized it was going to be I had no idea this was, I mean, massive and kind of overwhelming. But in a good way because I remember early on getting into this again learning about salicylic acid, and it's a lot. But it's amazing that we've been able to unpack as much as we have about it. Okay. Well that's that's aspirin. That's fell. Silk acid. That's a wrap. They haven't she we do sources. Yeah. Let's okay. So I'll start. I read a book called aspirin, the remarkable story of a wonder drug by Dr Mond Jeffries, and I just have to say this was one of the most exciting in grossing books. I've read on medicine in history ever. Go read it another book. I read was called dragon's blood in willow. Bark by Tony mount in this was about remedies and medicine in the middle ages. And I read an article about how aspirin might have been used our might have led to excess mortality during the nineteen eighteen flu. So all post all of that excellent, if you want to look up some of the stuff that I talked about, obviously, I will send links there is a few papers that really helped me with this. This one is cell Silic acid, a multifaceted hormone to combat disease by Vlade at all. There is salicylic acid and disease resistance in plants by dernier at all. And there is systemic acquired resistance by riles at all. And I'm just gonna have to send you the rest, but those were really good ones in terms of giving enough background that a, a dumdum like me could understand. You're not a dumped on that definitely not in this context. I feel like when we will post a list of all of our sources on our website, this podcast will kill you dot com. You can find all of this is that we used in this episode every episode. And we also have a good reads list where we keep track of the books that we site in our in our episodes and anyone can add to that list. So if you know that, yes. So if you feel like you that there's a particular book that you really enjoy about disease, added to the list fiction, nonfiction, whatever, and so it's been really fun to sort of for me to go through, and look at them because I see so many that I'm like, oh, my God. I wanna read that. Oh, I wanna read that. Oh, that looks so cool, although cool. So thank you for adding this neat. Thank you, Matt for coming on today. Yeah. Thank you, both for having me. It is always a blessed not only research these episodes, but to record them. I really appreciate the opportunity, Levitt real fun so much. Fun. And thank you to everyone who's listening. We really appreciate you taking the time to tune in. It's the best if they to blood will for the music in this episode every episode and until next time wash your hands. He filthy animals.

aspirin Fevers Aaron aspirin Tylenol inflammation Bayer Matt mechanism of action CDL malaria Erin Welsh paracetamol willow US Finn Samaria cough Egypt Bayer Iraq
Update on indoor scale problems.

Your Gardening Questions

03:37 min | 1 year ago

Update on indoor scale problems.

"This plant talk. Podcast is brought to you by stoke seeds for the best selection of vegetable flower and herb seeds available. Go TO STOKE SEEDS DOT COM cultivating successful growers for generation. Something that you touched on again a couple of weeks ago but is really important. Right now is to watch for that. Indoor scale indoor scale and other such vermin if you will now. I'm I was careless this last fall when I brought the plants in at because of a time and so on I did not get outdoor or the porch. I call them my porch plants. I didn't get them sprayed before brought them and right now. They're running fairly clean. However I have been growing some of the orchids for a number of years some newbies and I've lost a few as time goes on however They stay outdoors in the summertime. Which has been very very good for them and me A little extra watering but at the same time been a lot of fun. Now you bring them in in the fall and again. I did not even think about spraying them. Usually don't but I've been twice now. And and once was as new as recent as yesterday looking at them I had to move them all and as I put them back in place. I was cleaning them. I was using in my choice of of of tool. I'm using my fingernail. I had go along the outside edge of the leaf and the main rib and especially the tip end of the leaf and watch for anything from a sixty four th of an inch Tan to. Let's just say almost an eighth of an inch in Tan to Brown there the various stages they have hatched. It's one of mother. Nature's rules if you will. The orchids are now starting to grow starting to send flowers and so on as they grow their enemies know while they don't know but they've been conditioned to follow that life cycle. So they're out there Hell bent on destroying my orchids. So I'm scraping off. Now you can use a cotton swab at the touch of alcohol etc. I'd I'd just go directly to it And right now is the time. They're they're in insidious little thing. They almost look like the color of the of the fully itself but they're they're a Tan like. I say anywhere from sixty fourth of an inch on. They are almost always going to Gang up on on the under edge outside edge of the leaf to the tip and then down the mid vein now they can be anywhere including right down inside the plant. In that case I will break. Ah Toothpicks Stomach If you will so I can get down in there in a tiny little area with a Well with tissue that will be sufficient to break loose the scale but it won't be strong enough to scrape up the living parts of the plant. So I mentioned that I also know that in the past and probably continuing if you bring plants in that have spider mite on them. They can be Raising havoc at this point in time other such so. Check your indoor plants To make sure because aspirin comes on plant start to grow indoors and out as do their enemies plateau. Podcast is brought to you by stoke seeds for the best selection of vegetable flower and herb seeds. Available go to stoke seeds DOT COM cultivating successful growers for generations.

Tan aspirin
The Invention of Aspirin

Stuff You Missed in History Class

35:17 min | 1 year ago

The Invention of Aspirin

"Getting on the buses good side is just you giving yourself positive affirmations you never have to fake laugh at the bosses. Lame jokes because you're hilarious and awkward Chitchat. Chat with the boss would just be awkward Chitchat with yourself. Because you're a small business owner born to be your own boss and Amex can help with funding solutions for eligible business customers. So you can keep doing what you were made to do. The powerful backing of American Express. Don't do business without it. Terms apply learn more at American Express dot com slash business. This episode of Stuffy missed in history class is brought to you by Adt Adt offers you all of the latest innovation in Smart Home Security combined with twenty four seven monitoring ordering from the most trusted name in home security with Adt you get a team of professionals designing and installing a secure smart home just for you and you get your safety on the go whether you're in the car if you're at work if the kids are at school you're doing grocery shopping you just check out the Adt going up which has a handy SOS button you. Have your security courtesy handled so once again this show is brought to you by. Adt Welcome to stuff. You missed in history class. A production of iheartradio's how stuff works. Thanks hello and welcome to the PODCAST. I'm holly FRY and I'm Tracy Wilson For all of recorded history Tracy and certainly before history was being recorded humans have been experiencing pain of one form or another Yup Yep That might seem like we're leading into a very dark place but really we're talking about We we've managed in alleviated pain and today of course we're also talking about fairly minor ones in this case It's just as simple as running to your local drugstore or supermarket or even big box store to pick up nonprescription pain relief. We've easy peasy and we're going to talk today about specifically one of the possible pain relievers that you might reach for in such a circumstance which is aspirin From its natural obey Substance Alison to the invention of synthetic derivative form that we still use. The story of aspirin is longer than people might expect. And it also has its own controversy controversy and conflict For example there is one man whose name always comes up and is credited with inventing aspirin. We're going to get to him and whether he should get credit because there's been some challenges to that but first we need to talk about the ancient history Of The medicinal base of this as well as some of the other people who figure into the development of our knowledge about the workings of Salicylic acid and its medicinal possibilities. Yeah and just to be super clear. We're not suggesting that like every pain that a a person could have could be solved with a quick little trip to the store to now. I got a headache. I'm going to run across the street and get some yes. Yeah the General Day to day minor pains you're paying a minor aches and pains not the more serious stuff so salomon is found in the bark. Mark of the white willow tree and in winter green leaves as well as a number of other plant life in various concentrations and it can be converted pretty easily in a lab or in the human body into salicylic acid and then this can get a little bit confusing because sometimes the two seemed to be used almost interchangeably. Yeah even even in in my research there were moments where people were talking about the history of this and they were pretty casually tossing the back and forth but that's not exactly correct And we'll talk about how even in the medical community. That's been a problem at various points in time SALICYLIC ACID is. What's called Beta hydroxy acid and you have probably heard of it before because it is used to tout? Various skin cares all the time. And that's because Beta hydroxy. Acids are excellent exfoliating and unlike alpha hydroxy acids which are also very good experience Beta hydroxy. Acids are also really good at reducing wrinkles and improving overall skin texture. And they don't have the same tendency to 'cause you're tation that they're Alpha hydroxy counterparts. Do It is also Antifungal anti infective and it can be used to remove in. He'll epidermal. Oh problems like calluses and wirtz. In addition to all of that salicylic acid can also help with pain in that something that humans have known about for a very long time. Although they didn't have that name for it and didn't understand how this pain relief was relating to Salsigne the first record that we have of willow bark being used as a pain remedy. He comes from Samaria four thousand years ago and in addition to relieving pain it was also used to treat inflammation and fever and this knowledge of the extract Willow Willow Bark as a medicinal compound did not stay in Mesopotamia. They traveled the globe in China. Going back at least two thousand years willow was being used to treat everything from the common cold into hemorrhages. Hippocrates documented the idea of a tea made from Willow Bark to tame pain during childbirth right around the transition from the fifth fifth to the fourth century BC e several hundred years later another Greek physician Dia Score Routinely took advantage of the anti inflammatory properties of Willow Bark Mark when you're getting his patients. Plenty of the elder at Gaylon also wrote about their uses of extract of willow bark and then in the seventeen sixties Reverend Edmonstone Joan who was a member of the Royal Society. In addition to being an Oxfordshire Vicar conduct his own. Study of the potential medicinal properties of willow bark based entirely on on a hunch as an aside you will also see him mentioned as Reverend Edward Stone both show up. Don't be confused in his own writing though he uses Edmund but he wrote out his findings in a letter to the Royal Society titled An Account Of the success of the bark of the Willow in the cure of egg. US which he he wrote to the right honorable George Earl of macclesfield. Who was the society's president at the time so in this account stone made it clear that he believed he had identified something really important and he wrote in the opening quote among the many useful discoveries which this Age hath made there are very few better deserve the attention of the public than what I am going to lay before your lordship and stone goes on to describe in this letter how he accidentally tasted the willow bark of a tree and he was kind of blown over by how bitter it was and he noticed that willows grew in the same places that were common ailments so issues are intense episodes of fever or shivering? They've often been associated with malaria and stone believes that quote many natural maladies carry their cures along with them or that their remedies lie not far from there cures. There's so he knew of other bitter plants that had healing properties including the Peruvian Chinchilla Nutri which also contains Saxon in its bark so he thought the bitter willow growing so near to where aggies were common might similarly offer a solution to the fevers that he saw his community so stone said he looked for information on the willow being used before he did not have access to the various accounts and records that we mentioned because all he could find was the name of the tree and botany me books that he consulted he found nothing about its pharmaceutical possibilities. This is a way where we are very spoiled by the Internet. A- and search engines. Yes I often think when we're talking about Historical scientists mathematicians philosophers philosophers etcetera. Like what would they do with the command of information that we have at our fingertips in our pockets but so stone not finding anything himself yourself on willow ever being used in this way set out to do some experimenting and the Reverend Stone gathered a pound of willow bark over the course of a summer and then he put it in a bag and he hung this bag outside of a Baker's oven for three months and while it sat there it was exposed not to direct heat but from the indirect heat of the stove for this prolonged period period of time and over that time the contents of the bag dried out and just crumbled to powder once he had this powder stone started giving it to people in very tiny amounts. I I just twenty grains of the powder as dose so if there was anything toxic in the substance the negative impact to his patients would hopefully be pretty minimal. As the the people he was treating for Agu appeared to tolerate this little dried powder. He started giving them additional doses. Still Pretty small every four hours and then he carefully observed the results and his patients had some improvement but none of them were cured of their problems but as they still seem to have no negative reactions to this experimental treatment stone stone increase the dose noting quote. I grew bolder with it and in a few days. Increase the dose to to scruples and the Agu was soon removed so scruple is that initial dose. It's twenty Greens so stone was basically doubling. The dosage stone continued on with the study for five years noting that over and over and and fifty cases has patients argues were either cured or in a few very severe cases. They were made much better. Stones letter goes on to talk about the trees themselves and Hal abundant London. They are and how easy to access and he concluded with quote. I have no other motives for publishing this valuable specific than that. It may have a fair and full trial. In in all its variety of circumstances and situations and that the world may reap the benefits accruing from it coming up. We're going to talk about some of the advances in chemistry see that enabled scientists to more fully understand why willow bark helped with pain and fever but first we are going to pause a little sponsor. Break the separate is brought to you by homeadvisor. Home projects can be tough and finding the right pro sale with those projects can be even harder and it can really spark a lot of questions like how who I find a pro who can help and we'll do a good job and we'll get a fair price and luckily that is where homeadvisor can help from. Leaky faucets to major remodels and everything thing in between homeadvisor can matchy with top rated local pros in just seconds. These pros have been reviewed by your neighbors so you can see what other people thought of their work and with whom advisors this is true cost guide. You can see what others paid for similar projects in your area so you can check to see if you're getting a fair price and then to top it all off you can even go ahead and book. Appointments is online at a time that works for you. Hope projects have never been easier with homeadvisor so get started on your next project today to find the right pro at a fair price. I just ask homeadvisor go to homeadvisor DOT COM or download the free award-winning homeadvisor APP. HOMEADVISOR DOT COM or download. The free APP Has a child the first words out of your mouth were. You're not the boss of me. Boss moves are the only moves you you make and you never have to worry about the boss approving vacation since wait. What's a vacation? You're a small business owner born to be your own boss and Amex can help with financing options for eligible business customers. So you can keep doing what you were made to do. The powerful backing of American Express. Don't do business without it. The terms apply apply learn more at American Express dot com slash business so wow reverend stones work and his success with patients came from using willow bark. He didn't really understand the chemistry involved. He knew that it was the bar or something in it. But that was it and it wasn't until the eighteen. Hundreds that significant strides were made in isolating and identifying the naturally occurring agent that had these beneficial properties. He's in the eighteen twenties and thirties. There were a number of advancements in the scientific community's understanding of what it was about willow tree bark and other plants that offered pain relief and anti inflammatory properties to patients and every step was building on the work of one that came before it in eighteen. Twenty eight a professor of pharmacology in Munich named Johann Buke ner made a big breakthrough he was able to extract purify the compound that was doing all of that good and he named it. S- Alison that it is based on the Latin word for Willow Salix in the following year. French pharmacist already larue. Built on work he was able to isolate a pure crystalline crystalline. Foremost Alison in eighteen twenty nine and eighteen thirty eight Rafael period. who was a chemist from Italy was able to produce salicylic acid in a lab? He did this. By resolving the chemical structure of Saxon into a sugar and alcohol and oxidized the sells alcohol to produce salicylic acid the precise chemical structure of sell sell. Alcohol was identified by two German chemists at Marburg University ehrmann quota An email to mun but the end of the eighteen fifties and over the next fifteen years. That team's work continued until they were able to develop a process for industrial production. Shen of salicylic acid the haydn chemical company in Germany started producing synthetic salicylic acid for pain and fever in eighteen. Seventy four making them. The first commercial producer in the eighteen seventies. Thomas mclagan the Medical Superintendent at Dundee Royal Infirmary and Scotland had a lot of patients with rheumatism And he noticed that there were similarities between the symptoms of those patients and patients with fevers. That weren't related to rheumatism. The patients with general fevers fevers had often been successfully treated with Tim Shona Bark which as we mentioned in the section on Reverend Edmund Stone contains salesperson and so- mclagan decided decided to test the bark. Extract Saxon out for himself just as stone head. Although obviously there was a little more knowledge about it at this point in this case the doctor I tested the substance on himself and he approached this as a progressive test so I he took five grains and had no negative reaction and then he took ten Greens which was similarly similarly benign and then he took thirty with no quote inconvenience or discomfort and at that point he was convinced that Saxon was safe so he next used it to address. Wrestle rheumatic patient with a fever high heart rate and swollen and Achey joints. This patient was given twelve grains of Southampton at a time repeating the dose every three hours after seven doses over the course of twenty four hour period. The patient's condition had improved the fever and heart rate were both reduced significantly although they were still slightly above normal two more days of treatment reduced swelling and alleviated. The patient's pain after two more years of trials with his patients mclagan published at least his results in the Lancet in this article features eight case studies of patients with varying degrees of rheumatism. And he wrote quote. The sudden arrest of the painful symptoms comes in the coincident rapid fall of pulse and temperature followed Silla immediately on the administration of this alison that it is impossible not to attribute them to its use cases of acute rheumatism. Do sometimes improve in the most unexpected manner. But I never saw a case. Get well so quickly as those of which I have given details above love. mclagan went on to say that Saxon was the most effective treatment for rheumatism. And also that its use dosage and effects should be carefully documented. Interestingly he believed that salicylic acid which had been isolated and was favored by some medical practitioners was not as effective or palatable a treatment as salads then even during this time there was some confusion about whether the terms thousand and salicylic acid were two separate things among some members of the medical community. Yeah Yeah I did see a a note in article about mclagan that There was a doctor that wrote him an apology note because he got really mad that this guy kept confusing the two terms arms but this is what brings us to a familiar name. Bear the firm Farben Fabric. Barham Friedrich Bear and company started as is a DI company but in eighteen nineties. The decision was made that the company would turn its efforts to pharmaceuticals and this might seem like a weird gear shift to go from pigments is to pharmaceuticals but both involved chemistry and this was a new and growing field and additionally the company had a really good name among consumers and so it was able to leverage that brand trust into these new ventures. So we've been talking about. How practitioners like the Reverend Stone? Were very careful in dosage of Salomon. And how Oh and stones cases in particular. He recorded no negative side effects. But that is really not an accurate picture of the use of Earl salicylic acid treatment overtime it can cause significant issues with digestive health including nausea ulcers vomiting. These are all things that can come from using South Ilic acid as is a medicine over time. Yes Alison is more easily tolerated. We're going to get into Y in a minute but salicylic acid once. It's isolated is a lot rougher on the gastrointestinal tract and this is what leads us to the name that is most commonly associated with aspirins origins. And that is Felix. Hoffman and Hoffman Hoffman. who was born in eighteen? Sixty initially pursued a career as a pharmacist when he finished his education but soon he realized that he actually wanted to do some more in depth science science and become a chemist and so he went back to school in eighteen ninety three he finished his graduate work with honors and he joined bear as a chemist in their newly established Pharmaceuticals Goals Division in eighteen ninety. Seven Hoffman added the acetyl Group C H Three C O two salicylic acid. The result was ACETYL salicylic acid in. which would eventually come to be known as ASPIRIN? And this sounds like a really insightful experiments and you could say that it is but really Hoffman. Was acetyl eating a lot of different molecules. Alec you'll to potentially create patentable. Medicines bears early medicines Fantasy and Tannenberg were also developed using the same process in projects that were run by other chemists. The origin for Hofmans experiment has a number of different stories to it. One version is that his boss at Bayer Arthur aiken green had had tasked him with figuring out a way to make salicylic acid more tolerable. The other was that his father took sow slick asset for his rheumatism and was experiencing the negative of side effects that come along with using it. For long periods. So Hoffman was driven by a desire to help him. There's another man involved in this named Heinrich Dresner and he ran the pharmaceutical cuticle lab at bear and it was his responsibility to test. Hoffman's new substance and reser was slow to work with a CDL salicylic acid. He openly said that he thought had no value value and moreover that it can be damaging to the heart. There was another seed elated compound. Creative by Hoffman around the same time which dresser thought would be a lot more lucrative and that was heroin Hofmann had created it when he assimilated morphine but that was not patentable because it had been discovered by another scientists twenty five years earlier Bayer sold heroin as a pain reliever and a cough suppressant for years. Many other companies did too. We don't WanNa put that on bare you have probably ably seen as a I'm presuming if you're a listener that your history fan. You've probably seen like the old-timey adverts or heroin as like a magical cure all. Oh but after more than a year of this aspirin compound being developed dresser after getting pressure from Arthur groom who also kind of got got some other people at bear involved in the cause to kind of push for this thing to get tested. Got Back to Hoffman's acetyl salicylic acid and dresdner. I tested it on himself and then he ran an animal study and next bear Ram tests in hospitals. I can ruin started this more. Widespread trial of the new compound offering it to doctors to us as with their patients and the results were as hoped. This new medication successfully treated patients particularly as a pain reliever the full. Clinical trials were published rushed in early eighteen. Ninety nine Bayer was quick to recognize the financial potential of aspirin and we will talk about its entry into the market after we pause for another word from sponsor this episode is brought to you. By Bomba's everybody loves to feel like they are the super awesome person at the end of the holiday gift. 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It's one of the things I love about this company so you could do some good and give it fantastic gifts go to Bombay dot com slash history class and get twenty percents off any purchase during their big holiday sale November eighteen th through December fifth. That's B. O. M. B. A. S. S. dot com slash history class for twenty percent off Baba's dot com slash history class. This episode is brought to you by the all new two thousand twenty Ford Explorer. Tracy I know that you have been thinking about an interesting thing lately. Which is what your pick would be for the greatest exploration vehicle GEICO of all time? Yeah I'M GONNA go with. The research vessel petrol that was owned by the late Paul Allen found so many shipwrecks which our listeners love that we started to make jokes about it and this shipwreck. That wasn't found by that vessels. Well The all new two thousand twenty. Four explorer is the greatest exploration vehicle of all time time there are a lot of places that have been explored by other vehicles but this vehicle the Ford explorer is going to take you to places that you might not think of as explorations but really really can be for example. Maybe you navigate your life and you have to get around town which can be a whole big problem especially if you live in a city like Atlanta. We're traffic tends to be congested rested. Sometimes you just want to go on a great vacation and riding in a perfect vehicle makes it the ideal ride or even just mundane things like going to the grocery store. Sometimes that is a true feet to achieve. If you buy groceries the way I do you can do all of this. And more with the all new twenty twenty Ford Explorer. That's the all new. Are you twenty two thousand Ford Explorer. The greatest exploration vehicle of all time The German patent application. That bear file was actually rejected. Two other chemists in Europe had created the ACETYL SALICYLIC salicylic acid before Hoffman although those were in lab scenarios and even though they they submitted patents neither of those parties had been able to create a stable version that could go to market it but Bayer went ahead and filed a patent application in the US and that was accepted. It was written by Felix Hoffman. And it begins quote. Be It known that I feel Hoffman doctor of philosophy chemist signer to the firemen for beacon of elberfeld company of New York residing at Elberfeld Germany have invented a new and useful improvement in the manufacture or production of CDL salicylic acid and Hoffman described his process in detail in that patent paper writing quote in producing. My new compound. Pound can proceed as follows without limiting myself to the particulars given a mixture prepared from fifty parts of salicylic acid and seventy-five parts acidic anhydride. It is heated for about two hours about one hundred fifty degrees centigrade in a vessel provided with a reflux condenser thus a clear liquid is obtained from which on cooling pulling a crystalline. Mass is separated. which is the ACETYL salicylic acid? It is freed from the acidic anhydride by pressing and then re crystallized from dry chloroform. The acid is thus obtained in the shape of glittering white needles melting at about one hundred thirty five degrees centigrade which are easily soluble in benzene alcohol. Alcohol Glacial Acetic acid chloroform but difficultly soluble in cold water. On March six eighteen ninety nine aspirin was registered as a trademark name. You by the Bayer Company. The name takes a from Acetyl S. P. I r. from the genus of plants that are alternative sources of salads sandwiches. Spuria the end suffix was a popular one at the time in drug names heroin being another example. Yeah there are a number if you look at drugs being developed at the time that end in I am the first aspirin that appeared in tablet form rather than a powder was in nineteen hundred although powder aspirin continued to be offered and these various options made incredibly easy for doctors to prescribe. An aspirin can actually still only be acquired with a prescription up until nineteen fifteen. Even dosages that we today would easily be able to the by without one in nineteen nineteen Bayer lost its exclusivity right to use the name aspirin through its. US patent as part of the reparations for World War. We're one. The company had to sell its factories. Sterling Inc bought the rights to olive bears. US Drug Properties for three million dollars. The name didn't stay. trademarked trademarked under sterling though. And it's been considered a generic term in the US for decades in dozens of other countries. Though it still trademarks name bear was able to get the international trademark on the name back when it bought it from Smithkline Beecham for one billion dollars that large price tag was not only for the trademark on the name Aspirin that acquisition was is rolled into a larger deal that included other points and other drugs as well SmithKline Beecham had bought out sterling's worldwide rights so in countries where the trademark is still held. Aspirin was once again under the Bayer umbrella. Funny detail in all of this. was that exactly how Hoffman's work with house. ACID actually made the substance more tolerable. Bolt people ingesting. It was still a little fuzzy. Essentially he transformed it into a new molecule that one doesn't trigger issues in the GI tract and two is converted back to salicylic acid by the bodies. The pain and fever relief characteristics of. It's still apply. But that whole process was not really interested until the nineteen seventies. It was only after work in the second half of the twentieth century that the potential benefits of aspirin related to heart disease and stroke came to be known now how things actually sleep played out at bear related to the discovery of aspirin have continued to be debated we mentioned when we first introduced that segment. The two different stories about how the experiments is that led to the development of aspirin actually began but that is not the end of it in nineteen forty four forty seven years after Hoffman's development of Aspirin and the Bayer Lab Arthur Ikin Grin while being held at Torrisi in Stott concentration camp. Because he was Jewish wrote his version of the story in this letter. Which is the Bayer Archives? He said that he was the one he wanted to come up. With a version of salicylic acid that would diminish these negative gastrointestinal side effects. According to his account out he wrote down all the instructions and Hoffman carried them out without really understanding. Any of it. I can grew also published this account in nineteen forty nine three years after Hoffman's death. He published that in the German periodical pharmacy in the nineteen nineties. Walter Snyder Pharmaceutical historian and deputy head of the Department of Pharmaceutical Sciences at the University of Strathclyde Glasgow took up the cause of I- congruence credit and one of the key pieces of argument hinges on what he believed might have been a mistranslation mistranslation of one of Hoffman's 1897 notes which may have confused verb tense. A little bit while most translations indicate that Hoffman was saying the compound was about to be tested sneer put forth the idea that actually should be translated to indicate that it already was being tested. I e the work. That Hoffman was doing was corroborative operative of an existing process rather than developmental in one thousand nine hundred nine the one hundred year anniversary of the patent and Felix Hoffman's name Bayer issued dude a press release addressing this ongoing debate about Hoffman and Arthur. Ikin grew the release states quote the claim. That not Hoffman. But his colleague. Dr Arthur AIKEN GRUND is responsible for the development cannot be proven. The statement goes on to mention Walter Snyder and his assertion. That Hoffman was working off notes by I congruent and that should be given credit but bear stance was that I can. Green was Never Hoffman. Superior that they were equals and so it would be weird for him to have assigned him a task and that Snyder's claims contradicted established documentation some of the confusion. The company claims comes from the fact that I can grew did have a subordinate named Hoffman. But that was Fritz Hoffmann Not Felix the Bay your account points out that Arthur I can grew never claimed credit for aspirin until he was in his Eighties after instances over five decades when he attributed the work to Felix Hoffmann. Of course. There's a case to be made that because he was Jewish he might never have felt that he he had the agency in Germany to be able to do that. And one of the places. Though we're sneakers case for I can kind of falls apart is also noted in that press release so in his his paper on the subject. Snyder mentions that Hoffman was never publicly credited with the invention of aspirin until nineteen thirty four. The assertion layer is that this was an attempt to write the the Jewish. I can grew out of the record during a period of intense anti-semitism in Germany. But the problem there is that Hoffman was credited on the patent application all all the way back in eighteen ninety nine as well as in other paperwork that dated back to when he was doing the experiments in eighteen. Ninety seven. Bayer statement concludes by noting that both I can gruden been Hoffman. Were Researchers Working Bayer in eighteen ninety seven basically saying they were GonNa work for hire situation. The statement finished with quote. It would have made no difference France to either the company or the success of the aspirin brand whether one or the other is considered the first to succeed and the elation of salicylic acid for the first time in a chemically pure and stable form. Yeah it's easy for a big company to go. It doesn't matter who got credit. Neither of them was really getting anything out of it. But of course the different people involved evolved in this effort it matters agreed deal. We've talked many times that several times lately. About how scientific discovery and credit is an issue of great eight debates and Great Passion But which of the bear scientists truly invented aspirin will likely never be conclusively settled. It's it's interesting reading modern more modern accounts of the whole thing that they do kind of mentioned that this this debate goes on although some completely just go with the Felix Hofmann version and fascinating But that invention of aspirin he have some listener mail. Also I do. This is from our listeners. Summer and she is writing adding to us about our recent episode. The campus inference holiday special four and specifically the seven lucky gods and she writes. My name is summer. And I've been listening to your podcast for probably four years now. I started when I needed something to do while sewing costumes for the High School Drama Club. I run my family and I lived in Japan for nine and a half years now. My husband teaches at a high school on an American military base. I had to write in after listening to the seven lucky gods segment because I have a crazy story about them. My friend Amanda and I decided to do a seven been lucky gods tour. Last January Yokohoma many cities or areas have their own tours that can either be walked or driven in one day. I've been driving in Japan for many years now now so I felt confident and comfortable getting around but there are always surprises here. There are many roads that are technically to lane but in reality only one car can fit down them also also Google maps struggles with is knowing where the real entrance to a place is these two things conspired against us on our quest to get all seven of our lucky gods on her way to the fifth stop we were following. Google maps instructions that led us into a residential neighborhood with those two lane roads. That only fit my minivan. We went up a hill and in Google instructed us to turn at the top which made sense because directly in front of us was a set of stairs. Though I started a SPEC. This was not going to work as the road that I turned onto. You is now gravel. All bordered on the left by a wall on the right by a steep twenty-foot drop off with no guardrail. We drove very slowly on this road for about twenty meters and turned again only only to discover that we were now definitely of that was more akin to a sidewalk. It ended about twenty meters in front of us in stairs which we obviously were not going to drive down. I now had the unenviable task of backing up around two corners on a not road about seven feet wide in a minivan. Also did I mention the cliff drop loss on one side and my three year old in the backseat. Thank Heavens for backup cameras in my friend. Amanda who got out and helped guide me around the corners and the telephone poles when we finally got back on real road. We parked the car at laughed from the sheer terror of it. All we assume the stairs in front of us were a back entrance to the shrine and we wandered on him. Sure enough it was and we were able to get are very very lucky. God and continuing on though this time with a little less reliance on Google I look forward to doing another tour. Income Coulda in two thousand twenty. Although I will probably do it on foot. Thank you for creating such a fun and informative podcast. I always recommend your episode on Saco and the one thousand cranes to any friends that visit Hiroshima. That story is very close to my heart after directing a show on it and I wept like a child at the mention of the Hiroshima Peace Park. I we I get weepy. Just thinking about it see Thank you for being my company while I so hundreds of costumes that drive around on adventures in Japan Summer this is such a fun slightly terrifying story I agree. The backup. Camera is magic I'm glad you're safe. That drop-off sounds very scary to me. And I I I hope that your visit to all the lucky gods granted you luck for the rest of the year you you never find yourself at such a precarious position again If you'd like to write to us you can do so at history. PODCAST APP. iheartradio DOT COM. That is a newish email address so take note not the same as the old one you can also find us everywhere on social media as missed in history and you can visit our website missed in history dot com. If you would like to subscribe to the show you can do that. On the iheartradio APP apple podcasts. Or wherever it is you listen. Stuffy missed in history classes a production of iheartradio. How stuff works for more podcasts? For my heart radio visit the iheartradio APP apple podcasts. Or wherever you listen to your favorite shows my name is Brandon FIBS. I want you to do away with me. Aboard Apollo Eleven. We'll be covering the mission from start art to finish day by day hour by hour minute by minute suffused with original music and fully immersive sound effects. This podcast is going to be the next best thing being to actually being aboard Apollo Eleven. This is nine days in July new episodes arrive every Thursday through February sixth. Listen to nine days in July on the iheartradio APP on Apple podcasts. Or wherever you get your podcasts.

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Aspirin Pharmacology

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

13:49 min | 2 years ago

Aspirin Pharmacology

"They all air christianson here. Host of the real life pharmacology podcast today. I'm gonna cover aspirin and specifically with aspirin. I'm I'm going to talk more. So about the anti platelet activity that the the drug house, and how we use that in clinical practice, and some factors that you might want to think about as well as mechanism of action. And and all that good stuff as well. So other brand names that aspirin goes by Eka Tren bear, it's in some excedrin products as well when and I think this brings up a really important point. When you when you talk with patients about over the counter medications, you have got to be sure you're on the same page with them, and, you know, take excedrin, for example, excedrins generally considered for headache. But if you go look at different excedrin products, they've all got different ingredients. So. So very very important to understand what's in a medication and over the counter medication and make sure that info is relate back to the patient as to what to look for as far as the active ingredients go on the back of that label because so many brand names have different variations of products. And I after I've often often have to look myself to make sure I'm getting what, you know, giving something to a patient that I think they should be getting because you can often be deceived by brand name over the counter products, and what's in them. So with that we've got the mechanism of action for aspirin in. I did talk about end saids. More broadly in a previous podcast. So definitely go. Check that one out more at talk about some of the concerns with ensigns as a whole but its primary mechanism of action as far as the anti platelet active. Vity goes aspirin like other ends heads can inhibit Cox one and Cox two, and I'm and primarily this is going to block the production of thrombosis seen eighty two and this thrombosis in eighty two is important because it stimulates basically blood clotting it initiates that process in stimulates platelets to aggregate together in and stop bleeding. So I think you can kind of understand by that mechanism that aspirins going to increase the risk of bleeding there. So it is classified as an end said in addition to that anti platelet activity. We do have some analgesic anti paramedic anti inflammatory properties. These are generally at much. Much higher doses. Than the anti platelet activity, the anti platelet activity. We're looking at, you know, eighty one milligrams to three twenty five some of sometimes you will see patients, it seems like it's more geriatric patients use aspirin as their go to headache medicine and things like that. Generally, not something I I recommend. But you will see patients do that over the color sometimes and in the headache pain relief. Anti inflammatory type of fact, it's generally going to take higher doses with that. So maybe open six fifty and in more in that range as far as the the milligram dosage, so yeah, primary use in clinical practice is going to be that anti platelet activity. This is what you're going to see patients on eighty one milligrams once a day in the morning, for example, maybe three twenty five depending upon the situation. And what we're using the higher dose for. But again, if you see a patient usually dose down at once-daily, it's probably not for pain. It's probably four courteous, vascular prophylaxis, preventing heart attacks strokes and things of that nature. But we always want to make sure to ask patients what were using something for to make sure they know as well. Now, there's been some controversies and pushing Paul on cardiovascular prophylaxis, what doses appropriate is eighty one milligrams fine is three twenty five fine. And I will say probably in the majority of situations. Eighty-one milligrams of aspirin is okay. But there are some risk factors and and patients who have maybe had multiple events. There are some clinical factors in situations where you may get a provider that wants to do a higher dose. So there can be a little bit of leeway. There can be some exceptions there. But Eighty-one milligrams is probably acceptable for most patients one for sure situation where we're going to use that higher dose. Maybe a three twenty five milligram tablet is in ACS type situation. So that's. Acute coronary syndrome. It's a situation where you're maybe a patients presenting to the emergency department, or you know, with EMS the ambulance comes in a heart attack is suspected. In aspirin three. Twenty five milligrams is recommended over in eighty one milligram tablet in that acute situation where a heart attack is suspected. So that's one clinical situation where you might see the higher dose used and preferred over the eighty one milligram dose surgical procedures. This is always a question that patients Askar that I've seen patients ask a lot, and it can be difficult to end. There's no good blanket answer for whether an aspirin should be held or should be not held because different clinical situations and the intensity the aggressiveness of the surgery in what we're doing the invasiveness of the surgery, and how much blood loss is an -ticipant did. Does dictate whether aspirin should be held. You know, if it's a a minor, you know topical skin procedure. Aspirin might be appropriate to continue in that situation. And what you're going to want to lean on his the surgeon and in what they're doing with the patient and their determination of what the bleed risk is in that situation. So if it's going to be held typically aspirins going to be held in that five to ten day range, I would say most commonly in practice. I've seen about seven days maybe up to ten days in rare situations, but seven seems to be the number that I've seen most common. So again, whatever we hold aspirin. You know, the obvious risk is that, you know, cardiovascular event, if that's what we're using the aspirin for does maybe have the potential to happen, or you know, that's the perceived risk at least of stopping a medication like aspirin. That's a preventative type medication. So always important to to think about the the risk of the surgery the risk of blood loss as well as the risk of stopping that medication for a period of time as well. I adverse drug reactions with aspirin. I I would say with a baby dose aspirin adverse effects, particularly other than bleeding or bruising typically, aren't that common? So if I do see a patient, that's. That's maybe having trouble with aspirin. I might be a little bit of stomach upset or things of that nature or bruising and bleeding. That's probably the most common thing. I see with patients, maybe even more. So with geriatric patients that maybe have a little more frail skin and things of that nature. The the bruising maybe really really bothersome to patients. This is something that you're probably gonna come across. So we're always kind of juggling that risk versus benefit of aspirin. And we can certainly monitor hemoglobin in Amata Krit t to make sure that the patients aren't losing blood aren't having a blood loss. Maybe through the stool or something of that nature. GI bleed out. We can also check platelets to make sure that you know, this patient doesn't have some sort of underlying issue or or anything else that's dropping their platelets further which may put them at higher risk. For bleeding another thing to to monitor look out for with that bleed risk is other medications. So I and I played Litz antiquated, and I'll I'll touch on that with drug interactions a little bit there. So Jay upset, you know, you might get some some mild issues there GI bleed bleed risk in general is probably the thing. I see most common with aspirin because of that anti platelet activity. And and really what we're trying to do with the drug in preventing some of those those blood clots are rare things that you might see on like a pharmacology exam. But I can't say you see him too often in clinical practice so ringing in the years tonight is can happen with the overuse of aspirin or high dose aspirin, again, not incredibly common. But, you know, something to think about if you've got a patient presenting with ringing in the ears. Tonight is definitely asked them about over the counter us because there is a small segment of patients out there that will take some aspirin on their own for and pains or as nati- inflammatory, and then rise syndrome is associated with aspirin. That's always kind of a classic test question. So generally aspirins going to be avoided in pediatrics due to that risk. So let's take a quick break. From our sponsor men at one one dot com has a growing list of resources, nap, lex BCP SBC GP ambulatory care as well as good books that are clinically oriented great for nurse practitioners, PA's med, students physicians. Just good information clinical real world information in education that you can stop by. And check out. They're so mad at one one dot com. Slash store finishing up on drug interactions here. When I think of you know, particularly low dose aspirin. I'm looking at drugs that are going to have additive of facts or put ten she ate that risk of bleeding or thinning the blood. So other anti platelet medications. So something like cl- integral Presa grow which is typically used with aspirin post 'em. I for example. But you've got to remember that when we start using multiple agents that do similar things you can have that additive effect and bleed Rhys does go up so very important to remember that as we add more those anti platelet agents. Same thing with anti-coagulants. There's lots of geriatric patients with atrial fibrillation who are on a pixel ban or friend river rock Sebastian. And they may also be on baby aspirin, or you know, maybe higher does aspirin as well. And you've got to remember that that risk as we add those anticoagulant medications of bleed Kengo up as well. End saids notorious for causing GI bleed, I generally cautioned my patients on that. If they're taking aspirin on a dose of aspirin. If you use an end said in over the counter medication like pro or naproxen, you've got to remember that this is going to increase that risk for things like GI bleed. So I think that wraps up the podcast for today. Hopefully, you picked up a few pearls. It reminded yourself of a few clinical pearls with the use of aspirin. I give us a rating and review if you love the podcast on itunes, or wherever you're listening, that's greatly appreciated for those of you that have already done. So snag your free PDF. It's thirty one page PDF of the top two hundred drugs, if your student absolutely a no brainer. Go ahead and do that simply for following the podcast at real life. Pharmacology dot com. Thanks for listening. I take care of hope you guys have a great rest your day.

aspirin mechanism of action Acute coronary syndrome Slash naproxen Paul Amata Krit t Vity Litz Jay cl- integral Presa Rhys Cox seven days ten days ten day
NEJM This Week  July 16, 2020

NEJM This Week - Audio Summaries

32:42 min | 1 year ago

NEJM This Week July 16, 2020

"Welcome this is the New England Journal of Medicine I'm Dr. Michael Bearer. This Week July Sixteenth Two thousand twenty. We feature articles on Kagera Lower Aspirin. Stroke or transient ischemic attack and Aren a early warning for rheumatoid arthritis, flares row flu last cream for chronic psoriasis timing of renal replacement therapy in acute kidney injury, bilateral tumors, diagnosing and treating systemic racism and structural solutions for the rarest of the rare, a review article on acute ischemic stroke, a case report of a woman with early breast cancer during the Covid, nineteen pandemic and perspective articles on stolen breaths on creating real change at academic medical centers on racial health disparities and Covid, nineteen and on uncertain trust. Ticor and aspirin or aspirin alone in acute ischemic stroke or ti by S. clayborn Johnston from the University of Texas at Austin. Among patients with an acute ischemic stroke or transient ISCHEMIC attack Tiaa. The risk of a subsequent ischemic stroke is approximately five to ten percent. In the first few months, these investigators studied the effect of the combination of Tai Kagera and aspirin on the prevention of Stroke in eleven, thousand sixteen patients, who had had a mild to moderate, acute non cardio, embolic, schemic stroke with the National Institutes of health stroke, scale, score of five or lars or Tiaa, and who were not undergoing tromble isis or thrown back. Back to me. Patients were assigned within twenty four hours after symptom onset to receive a thirty day regimen of either Ticor, plus aspirin or matching placebo plus aspirin, a primary outcome event of stroke or death, within thirty days occurred in five point, five percent of patients in the Taika Gore Aspirin Group, and in six point, six percent of those in the aspirin group is schemic. Stroke occurred in five percent of patients in the Taika Galore Aspirin, group and in six point three percent in the aspirin group. The incidents of disability did not differ significantly between the two groups. Severe bleeding was more frequent with Taika Galore and occurred in zero point, five percent of patients in Tikal or aspirin. Group and in zero point one percent of patients in the aspirin group among these patients with acute non cardio, embolic, cerebral ISCHEMIA, the risk of the composite of stroke or death, within thirty days was lower with ticor aspirin then with aspirin alone. Peter Rothwell from the University of Oxford United Kingdom writes in an editorial that it is noteworthy that data from the current trial and two other trials, the platelet oriented inhibition in Mute Tiaa and minor ischemic stroke, point trial and the clopidogrel in high risk patients with acute non disabling cerebrovascular events. Chance trial might marginally favor clopidogrel in patients with Tiaa or acute stroke. However, the aforementioned trials recruited only a high risk subgroup of patients with Tia's of whom only those in the highest risk category, benefited from dual anti platelet treatment. This risk category was determined according to an A. B.. C. D. TO SCALE SCORE A. A composite risk score for stroke after a Tiaa of six or more range, zero to seven with higher scores, indicating higher risk of stroke, the bleeding risk associated with and aspirin might exceed the benefit among lower risk patients who make up the majority in practice, and so the current trial results should not be over generalized regardless of which combination of anti platelet drugs is favored for the high risk minority. All patients should receive aspirin immediately after Tiaa unless aspirin is, contra indicated, too. Many patients are sent home from emergency departments without this simple treatment that substantially reduces the risk and severity of early recurrent stroke. RNA identification of prime cells, predicting rheumatoid arthritis flares by Dana. Orange from Rockefeller University New York. Rheumatoid arthritis like many inflammatory diseases is characterized by episodes of quiescence and exacerbation flares. The molecular events, leading to flares are unknown. These investigators established a clinical and technical protocol for repeated home collection of blood in patients with rheumatoid arthritis to allow for Longitudinal. Sequencing specimens were obtained from three hundred sixty four time points during eight flares over a period of four years in their index patient as well as from two hundred thirty five time points during flares in three additional patients, consistent changes were observed in blood transcription profiles one to two weeks before a rheumatoid arthritis flare b-cell cell activation was followed by expansion of circulating CD, forty five CD thirty one PD PIN positive, pre, inflammatory, maximal or prime cells in the blood from patients with rheumatoid arthritis. These cells shared features of inflammatory Sino veal. Blasts levels of circulating prime cells decreased during flares in all four patients and flow Saitama Trie and sorted sell RNA sequencing confirmed the presence of prime cells in nineteen additional patients with Rheumatoid Arthritis Longitudinal Genomic analysis of rheumatoid arthritis flares revealed prime cells in the blood during the period before a flair and suggested a model in which these cells become activated by B cells in the weeks before a flair and subsequently migrate out of the blood into this I know vm. In an editorial Ellen Gravelly from Brigham and Women's Hospital Boston rights by anchoring their informatics analysis on the point in time, in which clinical flares occurred, orange and colleagues were able to obtain an unprecedented level of granularity that sheds light on the kinetics of immune activation, leading to flares, orange and colleagues showed that repeated measures of disease activity over time are powerful for the assessment of the baseline disease activity in a given patient, and for the identification of flares. We do not yet know whether their findings represent a consistent theme for all flares in all patients with rheumatoid arthritis since. The number of patients were studied, and medications were not considered, and it remains likely that distinct cellular and molecular mechanisms are at play in different sub populations of patients with rheumatoid arthritis. If the results are reliable, it may become possible to intervene to prevent clinical flares when the telltale precursor changes associated with flair Immuno pathogenesis are detected, and before clinical symptoms emerge. Colleagues show that intensively collected longitudinal data from a small sample of patients can be used to identify this regulated transcription will signatures that are not recognized by classical cross sectional studies. This study illustrates the exciting potential of longitudinal genomics to buy key antecedents of disease flares in an approach that may be applicable to the investigation of pathogenic and protective, immune, responses in a wide range of human diseases. Trial of roughly last cream for chronic plaque, psoriasis by mark level from the ICAHN School of Medicine at Mount Sinai new. York systemic oral phosphor, Diaz. Race type for PD four inhibitors have been effective in the treatment of psoriasis row flu last cream contains a PD e four inhibitor that is being investigated for the topical treatment of psoriasis in this phase to be trial. Three hundred thirty one adults with plaque psoriasis were randomly assigned to US Roaf Lula's zero point. Point three percent cream row, flu last zero point, one five percent, cream or vehicle placebo cream once daily for twelve weeks the primary efficacy outcome of an investigators global assessment I g, a score, indicating clear or almost clear at week six was observed in twenty eight percent of the patients in the row flu last zero point, three percent group in twenty three percent of those in the row, fluid last zero point, one five percent group, and in eight percent of. Of those in the vehicle group at week six, an it a score, indicating clear or almost clear plus a to grade improvement in the Inter trigeminus Area I score occurred in seventy three percent of the patients in the flu last zero point, three percent group, forty four percent of those in the row flu, last zero point, one five percent group and twenty nine percent of those in the vehicle group, the mean change from baseline at week six on the psoriasis. PSORIASIS, area and severity index score was minus fifty percent minus forty nine percent, and minus seventeen point eight percent respectively application site reactions occurred with similar frequency in the row, Fluemann last groups and the vehicle group row flu last cream administered once-daily to affected areas of psoriasis, was superior to vehicle in leading to a state of clear or almost clear at six weeks. Longer and larger trials are needed to determine the durability and safety of RAF flu last in psoriasis. Timing of initiation of renal replacement therapy in acute kidney injury by the standard versus accelerated initiation of renal replacement therapy in Acute Kidney Injury Start Aka I- investigators. Acute Kidney Injury is common in critically ill patients, many of whom receive renal replacement therapy. However, the most effective timing for the initiation of such therapy remains uncertain in this multinational study, three, thousand, nine, hundred, critically ill patients with severe acute kidney injury, were randomly assigned to receive an accelerated strategy of renal replacement therapy in which therapy was initiated within twelve hours after the patient had met eligibility criteria or a standard strategy in which renal replacement therapy was discouraged, unless conventional indications developed or acute kidney injury persisted for more than seventy two hours. Hours. At ninety days, death had occurred in forty three point, nine percent of patients in the accelerated strategy group, and in forty three point, seven percent of those in the standard strategy. Group among survivors at ninety days, continued dependence on renal replacement therapy was confirmed in ten point, four percent of patients in the accelerated strategy group, and in six percent of patients in the Standard Strategy Group adverse events occurred in twenty three percent of patients in the accelerated strategy group, and in sixteen point, five percent of patients in the standard strategy group among critically ill patients with acute kidney injury and accelerated renal replacement strategy was not associated with a lower risk of death at ninety days, then a standard strategy. Acute ischemic stroke, a clinical practice article by William Powers from the University of North Carolina School of. Medicine, Chapel Hill each year in the United States approximately seven hundred thousand people have an acute stroke. Understanding treatment options for acute ischemic stroke is important to ensure prompt administration of appropriate care or referral treatment is guided by the time from the onset of stroke, the severity of neurologic deficit and findings on euro imaging. By convention the time of stroke onset is established as the time that the patient was last known to be well, that is in a normal or baseline state firmed by medical history, intravenous thrombosis with alterplase or recombinant Tissue Plasminogen activator improves outcomes in selected patients with acute ischemic stroke when administered within four point five hours after onset later treatment may improve outcomes in selected patients with the treatment window extended to nine hours from onset. Intra Arterial Catheter based mechanical THRUM BECTON ME OF A. Large Intra Cranial arteries improves outcomes in selected patients with acute stroke when performed up to twenty four hours after onset, the benefit of Outta, place and mechanical back to me is time dependent, so assessment and treatment should be instituted rapidly in selected patients with mild acute ischemic stroke, who do not qualify for intravenous thrombosis or mechanical thrown back to me jewel, anti platelet therapy with clopidogrel and aspirin, when administered within twenty four hours after onset, and continued for twenty one days lowers the risk of recurrent stroke. A sixty two year old woman with early Breast Cancer Covid, nineteen pandemic, a case record of the Massachusetts General Hospital by Laura Spring and colleagues. A. Sixty two year, old woman was evaluated for a mass that had been identified in the left breast mammography revealed irregular mass with speculated margins, underlying the skin marker in the left breast with imaging characteristics, highly suggestive of cancer. All Tra- cinematography showed a solid mass measuring three point one centimeters by one point five centimeters by one point, two centimeters and normal left accelere lymph nodes core needle biopsy was performed. The patient was found to have clinical stage t two N, zero hormone receptor positive her two negative breast cancer. Before the emergence of covid nineteen, a patient with this diagnosis would be a candidate for upfront surgery. The Kobe nineteen pandemic poses a major challenge to the healthcare system major differences in management before and during the pandemic are outlined in this report and key principles are reviewed I during this pandemic, although the choice and sequence of method of treatment may be affected. The overall goal of management remains cure second. The benefit of treatment needs to be carefully weighed against the known risks associated with treatment and against the potential risk of transmission of SARS covy to to patients and healthcare providers third. The treatment regimen may need to be modified on the basis of the individual clinical and pathological scenario. Finally it is important to organize a multidisciplinary plan of alternative. That can be implemented in a resource constrained environment after discussing the care of this patient during a virtual multidisciplinary tumor board conference, it was determined that upfront surgery was not an option because of covid nineteen restrictions consequently neo atrovent endocrine therapy within a rotates inhibitor was initiated. The patient is currently doing well. Bilateral tumors inherited or acquired a clinical implications of Basic Research Article by William Phuc from McGill University Montreal. Bilateral tumors in paired organs are assumed to be hereditary in nature because a family history of cancer and an earlier age at onset are often associated with such tumors. Different models can show how tumors occur bilaterally impaired organs in an inherited I mutation hit model. The first hit occurs through familial inheritance of germline pathogenic burien from one parent, and is followed by second cinematic hits on the other parental Lille of the same tumor suppressor gene. However, the second hits occur independently in the two organs leading to bilateral to Maura Genesis. A late, somatic I hit model shows that in acquired cases, independent sets of to somatic mutations, affecting the same gene occur in each kidney after lateral ization, yielding a total of four somatic events and early Semitic, I hit model shows that bilateral tumors can arise from mechanisms independent of inheritance, such as through somatic alterations that occur in early embryo genesis, before laterals ation as shown in a recent study or matic mutation, followed by second hits that occur after lateral ization in each of the organs. The recent study shows that very early post. zygote events rather than inherited variants are likely to confer susceptibility to bilateral wilms tumors of finding with implications for treatment strategy and surveillance. Diagnosing and treating systemic racism and editorial by Michelle Evans from the National Institute on Aging Baltimore. For Physicians, the words I can't breathe our primal cry for help. As many physicians have left their comfort zones to care for patients with Covid nineteen associated respiratory failure, the role of the medical profession in addressing this life, defining need has rarely been clearer, but as George fluids repeated cry of I can't breathe while he was being murdered by Minneapolis. Police officer has resounded through the country. The physicians row has seemed less clear police brutality against black people, and this is stemming racism of which it is, but one lethal manifestation is a festering public health crisis. Can the medical profession use the tools in its armament? Terry him to address this deep rooted disease. Our Society expects physicians to live. Live up to standards of professionalism deliver state of the art, timely care with competence and integrity and promote the public good to carry out these duties, physicians citizens must recognize the harm inflicted by discrimination and racism, and consider this environmental agent of disease as a vital sign alongside blood, pressure, pulse, weight and temperature that provides important information about patient's condition. Medical Skill has allowed us to respond rapidly to a novel virus to save lives. We must also use our expertise to address racism and injustice, and to protect vulnerable people from harm now amid an acute public health crisis that is transforming medicine. Perhaps we have an opportunity to reset our priorities to face this deeper more chronic crisis as well. Structural solutions for the rarest of the rare underrepresented minority faculty in medical sub specialties, a medicine and society article by Kenny Doll from the University of Washington School of Medicine Seattle. The fact that medical sub specialties continue to have extremely low numbers of underrepresented minority faculty decades after National Workforce Diversity efforts began indicates the extent of resistance to diversification in these fields, the challenges created by this resistance are faced by underrepresented minority sub specialists and can impede academic success. The racial composition of any professional group in society is a product of racist or anti racist policies or norms not happen stance, but there are ways to cultivate the retention and promotion of underrepresented minority faculty members. These authors offer several tools that can be deployed at the. The division or department level to cultivate the retention and promotion of underrepresented minority faculty in the medical and surgical sub specialties after they have been successfully recruited I institutions can provide continuing education for leaders to help them prepare for under represented minority faculty, and to learn how to constructively advocate on their behalf second structural support time funding and expectations can be provided for mentorship and training for new faculty members specifically for navigating isolation, hyper visibility, stereotype, threat and institutional racism. Third Departments can provide support for under represented minority, faculty, specific, local and national funding opportunities. STOLEN BREATHS A perspective article. Biracial Hardiman from the University of Minnesota. School of Public Health Minneapolis. Any solution to racial health inequities must be rooted in the material conditions in which those inequities thrive. These authors recommend that healthcare systems engage at the very least in five practices to dismantle structural racism and improve the health and wellbeing of the black community and the country. Divest from racial health inequities, racial health inequities are not signs of a system malfunction. They are the byproduct of healthcare systems functioning as intended. desegregate the healthcare workforce. The healthcare workforce is predominantly white at essentially every level. Make mastering the health effects of structural racism, a professional medical competency in two thousand sixteen. We asked individual clinicians to learn understand and accept America's racist roots in two thousand twenty. It is clear that clinicians need to master learning the ways in which structural racism affects health. Mandate and measure equitable outcomes, just as healthcare systems are required to meet rigorous safety and quality performance standards for accreditation they should be required to meet rigorous standards for addressing structural racism and achieving equity in outcomes, protect and serve healthcare systems must play a role in protecting and advocating for their patients police violence racial inequities in Covid, nineteen and other forms of structural racism are concurrent and compounding public health crises in the United States the choice before the healthcare system now is to show. Not Tell that black lives matter. Creating real change, academic medical centers how social movements can be timely catalysts, a perspective article by Michelle Morris from Brigham and Women's Hospital Boston. The, deaths of Alton Sterling and Philander Casteel in July two thousand, sixteen, reverberated throughout the Brigham and Women's Hospital Department of Medicine destabilizing daily routines in the new academic year. Momentum for change had been building since the black lives matter movement burst onto national headlines in two thousand thirteen, they're internal medicine residents, enjoying them as a department and institution to reinvigorate the long essential process of recognizing racism within their environment and acting to address it. The residents declared that the issues that the black lives matter movement was making visible warrant external to or separate from their own experiences at an academic medical center, structural racism, discriminatory, policing and criminalization of black people affect healthcare. These long standing issues reflect the living legacy of our country's history of racial discrimination and its many tragic consequences, including genocide of Native American People Slavery Jim Crow Laws and eugenics. The question posed with simple. What are we going to do in early? Two, thousand, seventeen, the new be W.H. Of Medicine Health Equity Committee was launched to advanced action on health equity and engage new partners throughout institutions disciplines. Their experience shows that institutional change in healthcare is possible. The next frontier for Health Justice at their institution is that of structural and policy change. Racial health disparities and Cova nineteen caution and context up perspective article by Merlin Chow Kwanyan from Columbia. University New York. In early April Wisconsin and Michigan released data showing stark racial disparities in rates of COVID, nineteen cases and deaths in those states, many media outlets noted that the percentages of affected people who were black, were more than twice as high as the proportion of blacks in the overall population, similar disparities have since been reported elsewhere sometimes along with overrepresentation of additional racial minority groups, racial disparities have US become central in the national conversation about Covid nineteen front page headlines in the New York, and the Los Angeles Times have highlighted the issue as have elected officials at all levels of government. US Senator, Elizabeth Warren and representative John Presley have called for more thorough collection of racial data and in an open letter they fought the government for currently failing to collect and publicly report on the racial and ethnic demographic information of patients tested for and affected by covid nineteen soon after their statement, several states and municipalities began releasing data sets incorporating this demographic detail, but in documenting covid, nineteen racial disparities with must contextualized such data with adequate analysis disparity figures without explanatory context can perpetuate harmful myths and misunderstandings that actually undermine the goal of eliminating health inequities. UNCERTAIN TRUST A perspective article by Ken Wu and editorial fellow at the Journal. I know you are worried about. All of us are as well. Dr Ken Wu told the patient's mother. We are not sure why he is confused, but we are trying our best to find out. I cannot imagine how difficult it is for you, but our team will take care of both of you. Dr Wu carefully selected an accurate mandarin translation for his words. He knew this was a delicate conversation. Rennes stared at Dr. Woo, her demeanor unchanged after four days Dr Wu was the first person to tell her in detail, and in her language what they knew about her son's condition, which was very little, ren ends in had been about to fly home to China from a two week holiday in England when Zinn had a twenty minute tonic chronic seizure in the. Four days later he was still confused and teetering on the brink of another seizure, he was transferred to Dr Woo team so that they could figure out why, but all they had to offer were more tests and treatments that could cause more harm than good. The hallmarks of diagnostic uncertainty faced with another Chinese mother Dr Wu instinctively did what his mother had needed two decades earlier when he had been injured, he put one hand on Ren Shoulder, and the other on his heart he told his story and showed her the scar on his head, that bore witness to his experience Rennes expression softened albeit briefly. She recognized that someone shared her frustrations, but it did not la her distrust in them a few days later, one of their tests finally confirmed a diagnosis anti Md. a receptor encephalitis zinn was treated with plasmapheresis to remove from his blood, the antibodies that had been attacking his own brain. A revived and relieved ran accompanied her son when he left the ICU. Doctor Wu realized how much he had taken for granted the implicit trust in doctors, he expected from his patients and their parents. Our images in clinical medicine features a sixty nine year old woman with metastatic colon cancer coup presented to the emergency department with a two week history of dizziness and unusually colored stool. She had no associated itching or darkening of the urine. The physical examination was notable for Jaundice her Pat Omega three, and a diffusely tender abdomen the rectal examination showed silver colored stool. Laboratory studies were notable for hemoglobin level of seven point, five grams per deciliter, a total billy Ruben level of four milligrams. Milligrams per deciliter and alkyl phosphates level of three hundred sixty nine units per liter. Testing of the stool was positive for occult blood findings on C. T. of the abdomen and pelvis included a sequel mass and multiple liver metastasis, the appearance of silver stool results from a combination of white stool, associated with obstructive jaundice and black stool of Melania after a discussion of treatment options with the patient. A decision was made to focus on her comfort. She was discharged home with hospice care. In another image, seventy two year, old man who is referred to the hematology service after an evaluation for a one month, history of fatigue and pain in the right hip revealed abnormal results on serum protein electrophoresis, relevant laboratory test results included creatine level of zero point eight milligrams per deciliter, a calcium level of nine point four milligrams per deciliter and a total protein level of nine point, four grams per deciliter serum protein electrophoresis with Immuno- fixation, confirmed the presence of an I G G CAPPA monoclonal spike of five point five grams per deciliter a skeletal. Skeletal survey showed lyric. Lesions in the illion pubis and Kalvaria and a bone marrow biopsy confirmed seventy percent involvement of plasma cells with Kappa light chain restriction, a diagnosis of multiple myeloma was made examination of the plasma cells revealed the presence of cells with morphological features characteristic of signet ring cells. This type of cell is common in Moose Producing Adenocarcinomas, however in Maya Loma. The cause of its appearance is incompletely understood. It has been proposed that it is a result of large Sido plasma conclusions of defective immunoglobulins that displace the nucleus to the periphery. Treatment with an induction regimen of Cortes amid cyclophosphamide and decks and method zone was initiated and maintenance therapy was planned. This concludes our summary Let us. Know what you think about our audio summaries. Any comments or suggestions may be sent to audio at any J. M. Dot Org. Thank you for listening.

aspirin ischemic stroke rheumatoid arthritis US Covid clopidogrel plaque psoriasis flu Taika Galore Aspirin Aspirin Brigham Covid Taika Gore Aspirin Group New England Journal of Medicin Dr Ken Wu Tiaa ISCHEMIC National Institutes of health
Basic First Aid Kit

WCRI Flash Brief

02:29 min | 1 year ago

Basic First Aid Kit

"Yocum host web comic today a Basic First Aid kit look me in the beginning and crew injuries. I mean all you lead a lot cost of illness but we also tend to deal with sharp objects. He has not had an executive knife. Incident is not doing. You're right okay because if you want to sit up some sure really busy first aid kitten. That's what we're GONNA BE WORKING TONIGHT. First off most pharmacy will you finish. They will actually give you something to put your first aid kit in definitely take advantage of that available also make sure that you get a small thing of astronauts issue straight up. You want something for nothing better than aspirin in pin. Also make sure you get some sort of Yeah a lot of people. Don't do it but the cool thing here is that you can go with range or other issues. They Spanish can't be beat. Plus if you're new dance you're definitely going to appreciate having one of those around. Make sure you get a variety size bandages. Leaving just straight up one size does not all you want to get to me. Different varieties possibly can deal with any particular situation sets up and definitely. WanNa get a small pair of scissors to make sure that you can cut vantage the undersize if necessary again. It's just really nice to have so definitely looking into it. I cannot recommend cotton swabs enough definitely makes you have a carton full on hand. Because you're going to go through them if you have any kind of actual I can definitely not recommend contracts. Enough is just straight up using logic appointments and stuff so definitely got cartons you on hand being in various white minutes. You'RE GONNA WANNA look through stuff like antibacterial anti Clinton cream like newest. Were YOU WANNA? Watch somebody draws you with Burnley. Alec can work. Don't get me wrong when you this plan split. Let's not all artists have a green thumb. So you now. Also you're gonNA track down something. Stick powder sticky counter is essentially really cool became allows you a little bit faster? Farming Scab Jan will healing faster. Only problem is that you're probably gonNA find it more likely in a pet store than you will pharmacy Definitely interesting going to storing acting. Grab up first thing but do it. You'RE GONNA love. It lasted not least me. She Aggression Alcohol. Prep PADS worship. I'd either way it doesn't matter you need something. Basically work in anti septic when you're cleaning wounds and that's death waiting for it on C. That's very simple as a first aid kit. And you're GONNA yet. I hope that's helped. If it had checked me out web comic community interviews available any podcast attributed near you thank you have a great day.

Alec executive aspirin Clinton
Ben Askren Retires From MMA Reaction | The A-Side Live Chat

The MMA Beat

15:20 min | 1 year ago

Ben Askren Retires From MMA Reaction | The A-Side Live Chat

"Cantor from Cox has all your favorites all in one place and with the contour remote you can use your voice to fund them on live TV on demand and streaming APPs like like netflix video. And more see Cox dot com for details. What is up everyone? Jose young sear with 'EM FIGHTING DOT com impromptu episode of the aside live chat sitting next to me is Kaley my brother from the North in Toronto. Now Alex this is a very last minute episode. Like I said I call very last minute because we got some very last minute breaking breaking news and that is Ben. Aspirin has announced his retirement from mixed martial arts us on Airolo on his show or on. ESPN and officially hung up his four ounce gloves. So I'll put you on spot. What is your immediate reaction? After hearing the news I what are you expecting from one. Mr Ben Aspirin going forward well based on the comments. He made in his results in the sea. So so far I would say unsurprised unsurprised. The time is probably right if anything I respect that. He's probably that he's leaving when there's probably still no money to be made and I actually even though we're talking Hashtag may retirements. I actually think this is one that will stick forgotten for anyone who missed the the Hawaii show announcement he. He's I believe he needs to. He needs a hip replacement. That's probably it for you as a high level. ANIME fighter You you know. And he's he's thirty five years old. He's been involved in some form of combat sports since he was very very young so much wear and tear on his body so yeah unsurprising and I would also a welcome retirement. And that's I say that with respect to Tabet Aspirin. Yeah for anyone who's followed. aspirins career watched any interviews lately. I he's made. He's made it known that mix march was never his one true love he really loves the the world world of like amateur wrestling. Collegiate wrestling key coaches a lot kids. He coaches fighters coach Tyron Woodley. I coaches barber. He wasn't there for her last night but she's made sure to give him a shout-out but Ben Aspirin retired with a record. I believe of eighteen and two If I'm not nineteen into his last two losses were the only two losses he ha- ever had he lost to Hoard Mazda which everyone has heard or seen now especially instagram in five seconds fascists knockout in I. UCF Street and then he gets submitted. By Day Maya so getting knocked out by Hori Mazda against submitted by Damian. Maya had nothing to hang your head down dame is arguably the greatest grappler blur and UFC. Istrian Corey Boswell is the hottest fighter on the roster right now But a bearing those two losses aside what is going to be your lasting memory the From Ben Aspirin either inside the octagon outside the octagon any of the other plethora promotions He's fought under man. This is a guy for I mean I mean for the most part did things his way And you just got to respect that. I know it's a cliche but you certainly can't say about every fighter and I would say Aspirin Oscar. He's an original You know I'm not the biggest cleaned wrestling fan. But I know he was nicknamed Funky because his style was an orthodox so from his earliest super successful. NCW CHAMP EH days. He's had people kind of questioning how he goes about things so you know. He answered those questions in college. And then he gets in Tampa Bay and yes. He's very one dimensional but super successful missile rather the gate bell tower. Pick them up. He becomes a champion. He beats names like Douglas Lima Andrei Korsakov. People can say oh this was before they became you know before their there prime's C.. We won't know because I've had a rematch. Those are wins on Bonanza Record He did it his way you know and instead of going to the AFC after he went to one championship mature. There's a spat with Dana White. Very public saying like Oh. I'd rather watch grass grow. I think it was referenced. been asking some Dana Whitey like that Really really questioning whether aspirin was entertaining enough to be in the sea. So I'll ask her and went did his thing finding one and then and then he made his way to the UFC anyway and in this last year made plenty of headlines. Uh Uh drew plenty of eyeballs and in pro wrestling parlance put over some people major especially Muslims that the hormonal thing doesn't happen without this aspirin viewed in an aspirin running into his knee via the I mean people have been saying ever since he lost Damian in Singapore main event. They've really been cause is remember Ben. Aspirin was traded for Dimitrios Johnson. That I think that's going to be one of his lasting legacy stu he was part of the first real trade between promotions Johnson left. USC IN EXCHANGE FOR BANANA CREAM CITY wanted to test himself against the best In my mind what stands out the most not his inside the inside the cage or octagon. But it's one he said like. I might not be the best like I'm knocking. I might not retire undefeated but I at least want to try. I WANNA compete against the best. So he never walked around declaring himself. Like I am the greatest I on the greatest the greatest you want to try and he came to the AFC didn't work out and he said and he lost harbaugh's doll in five seconds handled. Donald loss better than most fighters would a decision loss. I mean he's he tweeted right away. He's like well that didn't go as planned. And then I heather. Hardy tweeted like everyone needs to stop picking on Bhaskar and this and that I've been asking like I deserve it. Don't worry about it so the way Ben. Aspirin handles defeat I think. A lot of young fighters can can really take from. I mean he said. I don't WanNa be like Ronda Rousey it happens the only thing we learned in that fight is horrid might as well has grainy and I'm not invincible. I can't can't that right. There just shows you kind of finer Ben asking is like he loses to the best and he owns up to it loses to Damian Maya and his interview backstage on. ESPN he goes. I just lost. Also the greatest submission artists arguably in the history of mixed martial arts so handles his losses very well was very dominant. I think people forget that he's he's it's like a record against Andrei Korsakov where he struggled like two hundred and something to like five in that fight you finish them and you finish. Finish them. Beat Douglas Lima. Who is it's either one eight one beat for people for Grace Fighter and Baladora history? Has the windows. Shinya Aoki has w over Robbie lawler say what you want about that by a w w just loses the two guys and calls career so I wish fighters I wish fans that really started to watch anime in. The last has two years like when the Rhonda's and the Connors everyone's rose. I wish they got to see him in his prime when he was not even tearing through people just like dominating like look. If you can't get up you can't get a groman off topic you shouldn't be champion. That's my mentality anyway but Yeah go ahead. I don't want to Romanticize is his style too much. Let's not I'm not gonNA pretend that pre UC BEN ASPIRIN DISA- Shogun esque. He was he was winning. He was not he was winning fights. I I'm I'm glad we did this because I wanNA bring one personal anecdote I was. I was in a glamorous Windsor Ontario when he fought Douglas Lima great crowd. Yes great crowd the card. Of course he was not very good and it was kept off by this aspirin fight where he held Lima down. And it's not asking Lima couldn't get up. The crowd became came so aggravated. I believe there was during this this twenty five minutes. There was two fights in the crowd so You know and those with maybe the most entertaining tonight so so regardless asking get to react and how to people sometimes it wasn't good sometimes style literally incited violence in those watching but again we can't discount that he was a winner at the end of the day and then regardless of his style managed to be an entertaining personality outside of the cage and that goes a long way chill. Sony Sony can tell you that she'll sewn in you know he had this exciting fights later but was known as very much a grind wrestler at your saint-pierre when most famous fighters of all time a lot of critics of his style L. But certainly Certainly a popular guy so aspirin is somewhere in that lineas that entertaining wrestler lineage. And certainly the sport is a little bit worse off for For his personality not being around. Yeah I mean his fights you saw them yourself when I was there on site for U. of C.. Two thirty nine for his fight against Horry Mazda. If you look at the numbers like John Jones is in the main event Amanda Nunez's Komen event. Holly Home Is there Luke. Rock hold like a young image based on that card. Who Do you think did the most numbers in terms terms of traffic and youtube views? Mister funky Mister Funky ask had a walmart sponsorship in that during that fight too so it just goes to show you that people do one. He spoke people listened. I remember vividly that first press conference. They introduced them to the AFC before his fight against Robbie lawler us all up on stage with all the fighters and he was going that everyone like he was talking to Kevin Lee. who was coming from Welterweight Talking Osmond? He's he's calling on. Called COVINGTON is calling out everybody and then he goes does any quote unquote submits Robbie Law. I don't a win is a win like I said Robbie lawler handled his loss. Well too and then flies immediately. Because I'M GONNA be Robbie lawler and I'm GONNA fight the winner dance cancel Hormuz Law and then. We'll fight for the championship. This is a guy that when he said it normally came true. You didn't end up beating hurry module but you have to assume if he had he most certainly would have been finding for title right away I think especially dominant horry Mazi doll like that but if that doesn't happen we don't get a beam championship the world. We don't see we don't we don't get holy Lori Mazda all being the biggest star in the AFC right now so yes. In terms of wins and losses one change clearly came. Came out the better in that trade again. I think you said it perfectly. Without Ben Aspirin there is no what lasts fifteen months twelve months of the. UFC has been wildly exciting. I think been asking and had a lot to do with that. Yeah you look you need. The world caused him to other become stars or to build other stars And I'm not saying that you have see has control over which one happens whether the fighter they signed become star are they building up but in this case it certainly worked out in billy another star and And I've joked online about you know how bad the trade looks but it's true you've got everything pretty much everything they wanted out of it. I guarantee they have pretty much zero regrets. Let's about making that trade so everyone should be happy. And I hope that Ben Aspirin finds happiness in moving onto wrestling coaching. And just being done with this this This nasty business of fighting and I will say everyone's GonNa question like was he a good fighter. was he a great fighter was he will beat her like he was an excellent prizefighter. And that's what this game is about is getting people to watch you fight and that is exactly what Ben asking. Just tell son-in-law is the whole argument jail sudden was good not great fighter Chill Sutton is a phenomenal prizefighter Ben. Aspirin is a phenomenal prizefighter. Like yes they might lose to people. But you're still watching that that those fights happen and you want you paying watch them lose or you want to see them win. Regardless everyone paid attention to Ben asking I really think the world of Mixed Smart Lars is GonNa Miss GonNa Miss Him. I mean I was backstage at UC Milwaukee which the last ever Fox card and he was the guest fighter and I was speaking so some of the AFC PR. I'm like what's it like. I've been working with Ben after like. He's he's a new fighter and he's already doing gas fighter spas and they're all like he's great. He'll do any interview they'll do it for ten fifteen minutes and then we you were doing the scrum. Which you've done a million of guests fighter scrums? It's going like sixteen minutes. And then the UC PR goes bad enough. Because I was having fun guys come on so it was like he wants to do that. Like how often do you get fighters that want to do media. You rarely get that any days. I mean you see Robbie Law. He's like I don't WanNa be here like fighters back like Nate Diaz and hard mazal forty minutes late immediate. A bashkir not only wants to do it. He'll talk to anybody and he'll talk to everybody so as a medium fan as a media member. I'm going to Miss Bennet Aspirin. Yeah for sure like I said from our perspective deputy and asset from the US's perspective asset. And I think history when he will look back on his career When we're out of this moment of got knocked on five seconds you've got some into my? I think history will very favorably on what asking accomplished as a fighter and he's not going anywhere still coach. Tyron Woodley I'm sure you're still the brothers. You coaches macy vibrant alley coaches a lot of those guys a up at Rufus sport so for his lasting legacy I think we I wish we had seen him fight. The George Saint. Pierre's the Roy McDonald's of the world the guys that he really wanted to fight at that time I remember when Carlos Condit was fighting Joyce. CPI banishments. I'll fight the winner tomorrow so like I wish we had got to see but asking versus Joyce. NPR obviously I would favor Joyce NPR very heavily. But there's always that question out there that Ben Aspirin called for so long and we never got that fight but finally the fact the fact that you've been talking about it tells you what a persona this guy created for himself before coming to the with no with no not being the number one spot you know. He people that that reputation as hey. What would happen if you bought George saint-pierre that they were even asking asking is a credit to his Promo ability well I was GonNa ask you what your lasting legacy is but I'll go first my lasting legacy in my mind. Is that Ben asking. He was made it outside of the. They say Dana go to one world series of fighting. He said forget. Dad's gone championship. Make more money. So he is one of those rare fighters that had a following following before he even got to the quote Unquote Big Leagues as fans call the UFC Baladora one championship. It comes over and is a media inserted into the uh not not immediate shop like the top ten range and everyone wants to see screen talk or fight and he hasn't even stepped aside the octagon yet. So it's I can't think think of many other fires. Maybe if like I said one of the pit bull brothers or Douglas Lee more like if MVP forever comes over to the UFC or anyone other from one championship. I'm sure there's going to be a lot. There's a lot of the stars that if they do. We'll have the same thing but Ben Aspirin captivated audiences with his words and then they brought those fans into the octagon. That is what I'm GonNa Remember most about aspirin. Alex what is your lasting legacy in for bad. I mean you pretty much summed it up a great point so I don't know if it's the crystals this new crystals thing which I'm against. You seem more lucid and focus than it was very impressive and I'll just add. I hope I hope that fighters other fighters can sort of learn some stuff from from about aspirin and big how he built himself up. It really isn't about your style McCain who said many times he was not the most exciting guy in the cage. You could probably count like if you took his top top five fights I mean they. They don't stack up to a lot of other people's talking bibles exciting. That's the fact but there's a lot to learn from how did what he did And it's not easy you know not. Everyone has his personality his background. His maybe some of the levers you might have had some fighters don't but there's definitely things to be learned and I hope The next generation of fighters kind of look at how he built himself up. And you know. Just take some things things here and there and and and it's not about being fake but it is about having your own persona and and trusting in it and and it can take you a long way. Well said Alex for Alex. This this is Jose this has been a very last minute impromptu. Quick episode of the live chat stick around on the Youtube page. And this and that We'll be back with a a a an actual live full at full length. Our episode of China Wednesday. I'm not gonNA tell you. The guest is yet This'll be up on like stitcher injures spotify. Google play all that fun stuff but for Alex. This is Jose we're up.

Aspirin Mr Ben Aspirin UFC AFC BEN ASPIRIN DISA- Shogun esque Robbie lawler Aspirin Oscar Damian Maya Alex Tyron Woodley wrestling ESPN Jose young Robbie Law Douglas Lima Douglas Lima Andrei Korsakov Collegiate wrestling netflix Toronto Dana White
Aspirin: The Wonder Drug

Stuff You Should Know

52:55 min | 8 months ago

Aspirin: The Wonder Drug

"Hey friends i wanna talk to you about the most important sandwich of the year and of course. I'm talking about the mcrib. Because the mcrib has true true fans there have been songs written to lament. It's goodbye when it leaves people driven over state lines to get a mcrib because it's not available in their area and some have even decided to just find ways to make their own mcrib when it's not available for the mcrib is here right now. And it's available for a limited time at participating. Mcdonald's holiday season means stocking up on some essentials like decorations and ugly sweater with the bank of america. Cash rewards credit card. You can choose certain. Three percent cashback on online shopping. The essentials have never felt more rewarding visit bank of america dot com slash more rewarding to apply now copyright twenty twenty bank of america corporation. Welcome to stuff. you should know. Production of iheartradio. Hey you know the podcast. I'm joshing news. Chuck and there's jerry out there coded in powder this stuff. You should know the aspirin addition much. Pick this. I've been reading a giant book on aspirin and yeah biography and you know behind the scenes backstage aid aspirin all the ups and downs like a behind. The music basically yeah. I don't remember why i picked this. I just don't remember but I did and i'm going to stand by it remember when aspirin. Od don itself. Yeah yeah june. it's that's some nasty stuff to od on to it. Turns out. I would think so. I mean not only the result but just the taste. I don't like the taste either. But haven't you said that. You're like a goody's headache dude. Yeah goodies or bc. I will You know that's a lot of aspirin. It's like you know if you will. We'll get to this but if you have like a hard issue they commend. You take something like eighty five milligrams a goodies into bc is like eight hundred. Fifty holy cow is a really. Yeah plus caffeine. It's a it's a big dose of aspirin plus acetaminophen to it's It's powdered excedrin. What is the same same formula. Well they're both different but yeah one of them is. I can't remember which one i think goodies is powdered etc. Yeah i think. Bc does not have these dominican and just has caffeine. And maybe more caffeine while. It's like the jolt cola headache powders but point is i don't take that a lot anymore in it I don't mind the taste. It grows a lot of people out. But i don't love it and i'm just like let it sit on my tongue and does offer ever right like a wash. It down very quickly. But i'm not like i got you better. You have no problem with the drain. Your okay funny guy so We are talking aspirin today. and it is kinda tough. I've realized to overstate the importance of aspirin. As far as like the world's medicine cabinet goes like there is no other drug that has been sold more than aspirin in the history of humanity. Did you know that sure. Okay i mean you know. It's it's it's the go-to or was for many many many many years until other instead started making the scene for decades and decades aspirin sort of the go to for a lot of stuff. That's true all right. Let me see if i can impress you with this. One of the great things about aspirin is it synthesized from nature that it's actually a perfect version of something that you would find in a number of plants salicylic acid But specifically it was willow that yielded up her secrets for mankind humankind to us as a medicine to make things better. Yeah i mean that's That's a lot of medicines and that's You know. Emily is getting really into herbalism here in the last few years. And that's kinda wanna her beefs. Is that The medical inform industries have synthesized things and gotten rid of a lot of the great parts of the plant. Sure she feels like our great use to human beings to make the synthetic versions. Okay fair enough. In this case though with aspirin. I would argue that. It is the improved version of nature's version. Yeah i think so. We'll we'll talk about why. But like i said it was the willow plant that people realized pretty far back chuck I believe it was at least as as As late as the sumerians Who i think they were. Clay tablets found that basically said are join. Saiki chai little willow leaf tea. It'll fix you right up. Yeah it was you know they. I don't think they had the name for it at the time. But it was sal saline the ingredient and you could boil it down to a t like you said you could dry dried out and powder that markup and pound it down and work through and get you know i guess an early version of goodies. You would I mean everything from the egyptians. there's the Abors papyrus which is a kind of a fun little cookbook textbook medical journal kind of thing right. That has recipes for myrtle and willow leaf tea for joint pain create chili recipe in there too. Great chile They didn't know about fritos back then but And by the way speaking of fritos yeah you know. There's actually a chapter in our book about fritos. Dogs there is. I know Is in it. I think that we don't talk enough about the fun chapters of our book kind of heavy stuff but there's also a chapter about fredo toes. Which if you don't have a dog. It is is the smell of corn chips. That ah dogs. Paws can emit. That was kind of one of the portland chapters. I think it was a good chapter for sure because we talked about that but about not just about how humans perceive the smell of dogs pause but how dogs perceived the world with smell. Different bacteria can make different. Smells pretty. it was a good one. I liked that one. Although i like our whole book to be honest. I finally got it two days ago. Who ray what did you think. Well first of all. I was very happy about how many they said. Yeah i thought they were gonna send me a couple of books. They send me a big box of books like you twenty five and it was just really great to hold in my hand and it's it's awesome. It looks great. It's the size we wanted. It looks it. Looks like a real book it is. It's the book which is weird to see our native book. I know did they put your name on the box. No your name was on. My box is that right. They put my name on my box to they just said what do you mean just said the book titled in by josh clark. Yeah yeah that's what it said. I think they just didn't print the whole thing. Okay well. I like my idea that they were going to personalize each of our boxes. Wow nice touch this just sounds like lazy box printing but i got you okay Well yeah. I wasn't like trying to rub it in thinking that they would personalized your box to but i'm going to save that box but whatever can you send me your box sure. Okay the box with a big oil pufus. There's a whole where where it used to say josh clark Anyway you can preorder that book Stuff you should know an incomplete compendium of mostly interesting things but back to aspirin This book was I don't even know i was talking about. Oh people like pliny. The elder in hippocrates had written about aspirin or wasn't aspirin yet but lean as basically early on it was all about reducing fever in reducing joint like arthritis joint pain inflammation and. It's still really good for that. To aspirin it turns out his non steroidal anti inflammatory drug and then said And it people realize that it was useful like you said for for joint inflammation for fever reduction which makes it a anti rettig Which i think is a great word. and we knew about this for centuries and apparently europe introduced to china for once rather than vice versa but then it just kind of fell away fell to the wayside Kind of out of human knowledge although it was still there it's just. Nobody was thinking about willow any longer until malaria became a big thing. When the age of discovery began in european started to colonize other parts of the world including south america. Malaria became a bit of a problem. and one of the remedies for malaria. We figured out was Sin shona since owner. Right i always said chinchilla. But i think it is in china. I always say chin shona too. But i'm looking right at it. And i don't see that first stage unless it's a weird pronunciation. I think i probably just been saying it wrong. Okay well let's let's say sinn shown event will pronounce it correctly for that our lives and that's a different kind of tree whose bark works really well to treat malaria and not just Treat malaria but also reduce fevers as well But the problem is getting it. From south america can be very very expensive or certainly was in the Sixteenth seventeenth and eighteenth centuries so it causes one guy european Dr a believer at least a researcher named reverend edward stone to look for an alternative for and he came upon willow. He rediscovered willow again for the treatment of fevers in inflammation. And by the way. I think we mispronounced. It is it shouldn't shona i just know it's neither that so it looked real quick. Says it's sunshine jonah. Okay i like that one like it almost sounds like it almost sounds like quimby saying so weird so son shona yeah edwards. Don't go looking for an alternative. And he starts looking at the willow bark and its properties and does a pretty decent study for back then in seventeen sixty three and found that a four hour administration of willow bark powder would reduce fever pretty consistently and like. I said it was a good study back then. there were some other europeans who were also extracting the active ingredient from willow and it was kind of happening all around the same time. I think a guy named laura did the best job of it the early eighteen hundreds eighteen. Twenty nine in What they got was the substance Right so Basically the the isolated. The active ingredient in willow bark and not just willow bark Sal seen or salicylic acid which probably sounds familiar If you've ever used some sort of skincare treatment say to combat because it actually goes in and dissolves the stuff in your pores out so it comes in handy like that When they when they isolated they they they found out that oh actually this this pops up elsewhere in nature. it's actually A kind of hormone that plan to use for their own immune response and you can find everything from willow or myrtle or meadow sweet to jasmine peas clover. Pops are very rare. It's a pretty common plant hormone and it was isolated finally in the early nineteenth century. Yes and there were a couple of other kind of important side roads on the way to aspirin that happen one in eighteen fifty three when a french. Chemist name gerhard. He invented aspirin by accident. But he wasn't very refined in how he did it. It was not a very good. Quality was pretty impure number effective so it was not paid very much attention to but we have to mention him and then in the eighteen fifties and sixties some german chemists figured out how to produce it synthetically They learned the chemical structure of salad late. Which is just kind of crazy to think that they could do stuff like that back then. that they were that advanced in learning chemical structures of something like that. I was impressed by that. But for sure yeah and they figured out how to produce it. Synthetically made it Very much available. Very inexpensive Big one all of a sudden it was a very popular fever. Reducer in pain reliever despite its side effects which are mainly stomach problems and tinnitus. Yes but the thing is with that Do with especially tonight. S and nausea. Like it can be really bad if you take too much. It's temporary but it can be a real problem and time. They also found out that it can produce long term chronic effects. Because it's so hard on your stomach because again you're using the same substance That you use to clean out the ports. Dissolve the stuff in your in your pores. The has a big effect on your stomach. And in fact we would find later on that it erodes your gastric mucosal. Your mc lining and that can produce all sorts of problems on its own in the short term. It makes you want to just throw up and die if you take too much aspirin. And that's what we figured out with. Cell silic acid and that was the point of aspirin to figure out how to create how to take this really useful important drug that had been known for millennia by this time and make it so it was. It didn't have any of these unpleasant side effects. That's where aspirin came from. Yes maybe we can take a break and come back and talk about Very sort of legendary company out of germany called buyer right after this Hey everybody wanted to tell you about blue moon beer though one of a kind beer with a beautiful appearance in a bright taste its well crafted with a twist of flavor and you're going to love it him in slice little orange up so that in their delicious the brew master in the blue moon founder was inspired by the very flavorful belgian wits. He enjoyed while he was studying brewing in brussels. Said how about a little bit of valencia orange about a little coriander about some oats wisely unfiltered in. It's going to be nice smooth and creamy. And what he made was a full flavor beer unlike any other someone once said when they were tasting the beer a beer. This good only comes around once in a blue moon chuck. That's right and you can have blue moon delivered to your door by going to get dot blue moon beer dot com finding delivery options near you so add a special touch to your holiday season with brightness of blue moon celebrate responsibly blue moon brewing company golden colorado ale folks twenty twenty. It's been a challenging year for all of us especially small businesses so pay pal is offering the chance to win up to ten thousand dollars in a sweepstakes along with two thousand and twenty prizes to help out small businesses. Yeah so businesses can start helping customers shop safely right from their phones with people. Qr codes if your business. All you have to do is go. Download the pay pal app generate your own unique. Qr code and start taking payments plus as you take payments over five dollars between november eighth and december. twelve you're automatically be entered for the chance to win one of those two thousand and twenty prizes so small businesses. You need to sell safe and you could win big. There are ten chances to win. That ten thousand dollars in hundreds of winners will get a five hundred dollar prize each week. Start using pay pal. Qr codes to accept payments for a chance to win up to ten thousand dollars get started at paypal dot com slash s. y. s. k. Or download the app. It's people dot com slash s. y. s. k. No purchase necessary ends december twelfth. Two thousand and twenty subject to official rules If you heard me say buyer and you're thinking dude it's bayer aspirin. what are you german. No not german. But that's how you pronounce it there. It's buyer we pronounce a bear over. Here they were originally a die making company but like so many other companies involved in chemistry They could pivot very easily. Then you start discovering things when you're working in chemistry that might make you more money and that was the case with buyer and they set up a pharmaceutical weighing and said hey you know we're discovering these other things and you make a ton of money in pharmaceuticals and this is just sort of the beginning of that. They had no idea what they're onto but they they started a pharmaceutical wing and said one of our first things we wanna try and do is to create a version of sally. Silat doesn't have all these nasty side effects. Yeah and there's a. There's a standing story in the chemistry com community That a guy named felix hoffmann a german chemist who worked for bear Was trying to figure out a way to make salicylic acid More easy on his father's stomach is had rheumatism Which is a chronic inflammation of the joints and he had to take cell silica a lot so felix hofmann was trying to figure out how to help his dad out when he stumbled upon the the recipe that would become the recipe for aspirin. Right so All of this led to one of the most popular drugs in the history of the world. There is some debate with everything. Like this It seems like sometimes it's hard to tell who exactly is given credit history is written by the victors and In this case while there's a there's three men there's a fourth dude named karl deutsch. Berg is included as being a big person in the development because he was a marketer and his marketing skills were a big big reason why aspirin was so successful but A lot of people point to feel hoffman as the quote unquote inventor of aspirin because on august ten eighteen ninety seven in his notebook injury. He described adding Attic and hydrate anhydride To sal silat and created aspirin. I'm going to say it if you say it. It's called aspirin seal civil man As acetyl salicylic acid. Yeah it's it's kind of fun to say has a cdl sale of salic acid. It's the acid that you love but calls it aspirin because it's easier and he can call it that legally because aspirins our proprietary up in emma's we'll see put a pen and that well something we leave that in sure all right. I think that's our gift to the listeners. Some end of the years eighteen s right there that means our our brains are entering the december mush phase. Yeah boy is. I'm looking forward to that break in new york we. Yeah everyone. i think we said this before. We take a few weeks off at the end of the year. And it's just Do not have to research stuff for three. Weeks is really nice. That's all you got. You guys don't notice because we make sure we record extra episodes in advance but we actually do. We bulk up the kitty as we say. That's right so Just just real quick to put a button in this felix. Hoffman is is Said to be the guy who created this guy named arthur ikin gruen said later on. He actually wrote a letter to bayer from a concentration camp during the nazi The third reich Because he was jewish and he said i was the one who came up with this But my my records were expunged by the nazis. Other people like. I'm not sure if that's true or not and a guy named heinrich dresser he said it doesn't matter if it's true because i rediscovered this stuff. I told both of these guys not to mess with this. They did anyway. I took their research published. It didn't give them credit. And now i'm am the one officially who is listed as the inventor of aspirin even though it was really feel hoffman and possibly arthur. I can groom who did. Yeah and i guess you could do that. If there isn't any patents being filed You could literally just sort of publish something in steal someone's work yeah Is unannounced gonna wear to think about. But i guess the law was the law but they did file patents and i mean bear realized pretty quickly. This is at the same time they were coming out with heroin to bear had to really big hits like right right with from what i read. Within a couple of weeks of each other and felix hoffmann was central. The both of them but with aspirin they were like this is kind of a big deal everybody loves sell silica acid and the effects that it has but they heat the side effects and we just got rid of them so they patented and they came up with the name aspirin so the is a nod to the As sediq anhydride the acetyl part The spur is a reference to the botanical. Names spy rea- old maria. Which is the name for meadow. Sweet another source of his Salicylic acid right. Yes so that would be aspirated. Then they added the i n. at the end because that was just sort of one of the naming conventions for medicines just like we have a cane like cocaine and Cicilline for antibiotics. They would add an i n so aspiration became aspirin. Get so if you picked up the box and you're like as per. What is this they get to the end and see the i n it'd be like oh it's a medicine that's right. So germany patents this in nineteen hundred in the united states After patenting it in germany and everywhere they could they would try and get a patent and it's been sort of an interesting story since then because after world war one And this is. I didn't even know this kind of stuff happened but Germany had to surrender their patents to countries that had defeated them and one of them was aspirin so they couldn't prevent competitors all over the world for making their own version They did retain the trademark in a few different countries. But that is like you said earlier. That is why you won't see aspirin or you don't have to list but a bit listed with a capital aid because it is It's just one of those. What do you call it proprietary fm. Yes i love those. Yeah those are great. Yeah you don't have to list. You don't have to say aspirin aspirin correct I'd some historians actually make the case that world war two happened because germany was treated so harshly after world war. One that it led to such tra- conan Basically revenge on germany. The german people that allowed a guy. Like hitler to rise rises this populist and gain control. Yeah so yeah. I didn't know about the patents either. But that kinda jibes and dovetails with that whole view. It's like give us all your art in patents. Right what else you can ask for land. Sure i guess old. It's sure and they did do that. Remember the the the nazi gold episode so There's another side story to all this came out of world war one as well In that there is embargo on finol By england england said. Hey we make a lot of female over here and it's an active ingredient and a lot of stuff including aspirin but not just aspirin explosives to which is one big reason why we wanna keep a lid on this thing and we're going to make sure that germany doesn't get any. There wasn't anything official in the united states banning anyone from selling def- of all the germany. But it was definitely looked like as you were aiding people who are at the very least the enemy of our enemy if not our enemy yet because we had entered war. One yet But that didn't stop. Thomas edison from selling finol to the german sturm world war one did no. He was Germany was looking at a it. Losing one of their most profitable drugs and said all right. We're going to send a spy there To secretly by fina. From thomas edison. Because he's got loves to blow stuff up he's lousy with it and i think that it was just exposed when one of the conspirators accidentally left his briefcase on the train and it was a real black eye on not only by a but edison as well. Yeah and i mean like a lot of people are like. Oh well you know they were. They were trying to keep the germans from having aspirin during world. War one again. You could use phenol to create tnt in other explosives so that seems to be the reason. Why which makes thomas edison. He actually created the phenol himself. And selling it to the germans. All the more shady. Yeah totally so. It was definitely a blemish on on edison for sure And he eventually stopped selling it to them and then donated the rest of the us army. I believe right so buyer is selling a lot of aspirin as a powder. It i kind of like you know what we were talking about earlier but they figured out that people and this kind of how most a lot of medicaments were powders at this point and i think aspirin from buyer was one of the first ones to be made into a tablet and they said hey if we can compress the stuff into a little tube People won't make people like wretch with disgust from how bitter it is. You can just pop it in your mouth. Wash down with some Some liquor sure or apps or something some schnapps. Ps impeach ops and people will take it more readily or at least not want to not take it and it really really worked in. That really popularized the use of tablets. Kind of from that point on. Yeah not just with aspirin with all medicines. I introduced the public to it and bear was actually with their aspirin. They were also. I think we talked about this and Tylenol poisoning episodes that they were the ones who introduced the cotton ball to pill bottles and they didn't to keep the aspirin from breaking because they were worried that somebody would take broken tablet and it would be too little of a dose or they would take a bunch of broken tablets to be too much of a dose so they put the cotton in there to keep them from breaking and with the advent of gel caps and coded capsules. And all that stuff. There's never been a need for the cotton ball any longer. But we've all gotten so used to it we Would be suspicious of opening a bottle of pills without even though. It's totally unnecessary now. I love that little cotton ball. That's a great great great It's at least one of the better Cotton ball facts out there. Well i like anything that can be re purposed like a twist on a loaf of bread. Ties that up. Oh sure or unit you gotta use that cotton ball you got a great like you stick it back in your pill bottle for d you. Yes okay. I actually go to the trouble of taking it out and putting in like a total. Oh that's right. I try to use those things Whether do is at his rapid toothpick with this cotton. And i use that as your swab bad at all. Yeah the toothpaste. that came with What what comes with a toothpick. I guess from the from the pig in a blanket or someone when you went and use the bathroom for free at a shoney's refused to eat there as still have all these things. Leftover from being a kid from the lower middle class like it feels weird to throw away twisted or era or those rubber bands that come around to spiritus. Yeah yeah who throws Away nobody that stuff. No sensible human being. I don't know about using the cotton from a pill bottle as a q tip with a toothpick textually. Very dangerous chuck bennett. I like it a spirit behind it. You know what i mean. Yeah you should not do that. Because a q tip or a toothpick is way to stabby to be putting cheerier have for sure and you should be using those Your swabs anyway. Right from what i understand. I win one more fact when we're cotton. Based fact member. Tips were originally called baby gays. That's right yep little baby gays what was there from your wax up. Maybe or ear candling. Maybe maybe i can't remember. Don't do it don't your kindle. Everyone know at least got that shirt. Now for instance let friends ear candle right teenage ear. Candalyn don't do it. So buyer is selling a ton of aspirin. They've always sold a ton of aspirin. I think the most recent stat that ed was able to dig up from about nine years ago in twenty eleven Worldwide there was about forty thousand tons of aspirin produced in the us Americans were taking ten billion aspirin tablets. A year billion lot. Aspirin in nineteen fifty It was the world's most purchase drug according to the guinness book of world records. I also read that in argentina in part because they have changed shortage like a legit one going on there. I'm one of the things you might get as change at the grocery store gas station or whatever is a couple of tabs of aspirin. Oh nice sure if you not sure. They love their aspirin there for sure so aspirins one of those drugs where for many many many decades they had no idea how it worked It was prescribed a lot. It eventually made its way to over the counter in the nineteen twenty s. It was one of these things where they knew it worked because they they did tons and tons of studies where like this stuff is really effective and the side effects. Aren't terrible as long as you're not using a ton of it. It's pretty safe. But it's really complex when you try and figure out how exactly chemically any drug works in the human body because of what happens when it gets in your body. It's just it's. It's really hard even still to pinpoint the exact path something takes when it's a lot easier to say well. Hey who cares. We got two thousand studies that show it works who cares what chemical processes at work. Yeah we just know that it does work in this way and we also know from all these studies that it has this side effect and it might affect this group more in this way than other groups Apparently aspirin has the largest chemical database of any compound anywhere I don't know if that's true or not. I read it in a croatian brand profile of aspirin By it's a great. Knock your socks off kind of fact if you ask me yeah they. They eventually did learn didn't they. They definitely did learn that. It does work. And exactly how i guess. Yeah that is kind of one of those rare examples of how we did figure it out. Isn't it. I think so In the late sixties and early seventies And they were using a building off the work of harry collier john von priscilla piper They figured out that the was a substance in the body. It's weird. They have figured it out in a roundabout way. 'cause they figured out. What the substance was that actually causes inflammation than in the body which is The release of prostaglandin and they figured out that insides actually stop this from happening an aspirin inside like we said and so in a roundabout way. They ended up figuring out how it worked. Yeah and so. Prostaglandins are like a whole class of hormones that are produced at the site of like an injury or an illness to help your immune response like inflammation pain all sorts of stuff that basically says like this needs to be taken care of in the. We need to get some some immune response here as fast as possible and so aspirin blocks prostaglandins from being released By enzymes called cyclo oxygen. As which kind of kick off the production of prostate gland. And they figure this out. This is how it works. This is how the anti inflammatory process works. And it's kind of a. It was a big enough deal that john wayne received the nobel prize for nine thousand nine hundred eighty two for medicine. Yeah and they also figured out and this is kind of key with aspirin Not only does it Does that enzyme inhibit that release but it kind of can do it permanently. Which is what separates aspirin from What's one the other one. The big one Advil advil yes. I'm blanking 'cause. I never take any of that stuff really. I'm an advil guy. Try not to take it. 'cause i don't want my kids to blow up inside of my body but Like when will you take it like headaches. Basically just a headache. If my headache is bad enough i will. I will take an feels. Pretty rare that i actually do but Yeah i mean that's that's that's my go-to because the other stuff doesn't work like tylenol doesn't work. I mean it doesn't do anything for me. It's weird you get headaches like regular No it's pretty pretty. Infrequent say i have been like the last couple of weeks But yeah. I probably have more evelyn last couple of weeks than i have in the last couple of years in the run up to the election. That's pretty funny yeah. I don't never get headaches. I mean the the rare hangover headache. But i don't get just like regular headaches for no reason Yeah no i. Normally don't either. So what do you take you take away. We established a spec- right. Yeah and that's again just for hangover cures. I hate that. That's the only time. I use that stuff but because i don't want to come across his a drunk but it's the rare the rare hangover remedy. Gotcha okay yeah. I think that's what most people use that stuff for to. Yeah it's it's the caffeine and they're really gives you a little boost. Sure but you know all you gotta do when you get into when you're approaching. Fifty is learn when to stop drinking right but the problem is as you're approaching fifty. It takes like one drink to get a hangover. Oh no really sure now. That doesn't happen to you. Know i'm good okay So there was one other thing that happened to when when people were studying aspirin like like this is the point. So many people are taking aspirin that an average dr conduct like a basically straw poll or some sort of study on his patients or patients. not to investigate the effects of aspirin. That's exactly what happened with one doctor. And i believe the fifties name lawrence craven who basically said. I've noticed that there's some sort of weird connection between more blood loss And tonsillectomies that. I'm performing on my patients. It seems like the people who take aspirin regularly. bleed more and he figured out that aspirins. A blood thinner from this. Yes and I guess let's take a break now. It's going to save something for a Surprise but that was the surprise. 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And it's powered by oxygen activated by the air we breathe and the water we drink. You've gotta try oxley versatile stain remover yourself to work the magic with arctic clean good oxley dot com all right so we spoiled the big Surprise which we josh foil. The big surprise which is the value of aspirin More and more over the years has been especially once other insides came on the scene and took a lot of the market share has been less fever. Reducer less pain reliever in more anti coagulant and more. Hey this can really help you out if you have potential heart condition. Yeah because they figured out. There's another prostaglandin. Throw back saying eighty two that forms platelets in the blood. Like if you have a cut or something like that and your blood eventually klotz. You can thank thrown boxing. A two for forming that the the platelets joining the platelets together and aspirin specifically keeps that from happening. And it like. You said other incidents don't do that. It's just aspirin from that discovery. Aspirin was saved from probably obscurity. Yeah there was a point in the. I think the seventies eighties nineties. Maybe even where aspirin didn't even make the list of top ten over the counter pain relievers. It had fallen so far out of favour. Yeah it was like your parents pain reliever right not cool. It was not hip. Aspirin was going the way of the dodo. And then they discovered this anti coagulant Sort of i mean not a side effect. I guess it just became a across use or something and then it became the main news and there are a few different reasons. Why you might take something like It's usually like a baby aspirin. It's sort of depends but It's always very low dose primary prevention. If you've never had a stroke you've never had a heart attack but you may be at risk for something like that. Your doctor might say you want to get on a daily baby aspirin because the benefits are somewhat uncertain and there are other risks. Like again thins the blood. So if you if you get cut or something you're going to bleed a lot more and they don't exactly know why but it affects It helps prevent heart attacks better for men strokes better for women so weird. It is very weird but that falls under the banner of preventative Aspirin taking yeah because it can cause bleeding and it can also cause potentially gastrointestinal bleeding from messing with your stomach. So bad. Even a low dose but a chronic. Low dose That they say unless you have a high risk you probably don't wanna start that regimen everyday so Basically don't start taking aspirin without talking to your doctor. i like. that's one of those caveats that you wanna you wanna say to. Yeah yeah absolutely Secondary prevention is the next one If you actually had a vascular event If you've had a stroke or a heart attack then you probably almost assuredly be prescribed to take that daily low dose aspirin because it is statistically significant That found there are large large reductions in subsequent heart attacks and strokes. If you've already had one. And then he started that low dose and that nuts. yeah it's amazing Like they there was a study. In nineteen eighty-four. The estimated was a british study that was published in the british medical journal That aspirin probably saves a hundred thousand lives a year back in the mid nineties. At least just from that secondary prevention. It's amazing and then there's a cute vascular events eeg. you're having a heart attack or stroke right now. they say. Go take an aspirin at least one aspirin. Maybe two and it will actually possibly save your life. Yeah i mean they've been study after study and it has significant increase in survival rates so chuck there some other weird stuff that they're like. We don't really know how this works. It's just typical aspirin stuff. We just know that it works That are starting to become like a pretty substantial body of medical literature about other benefits that aspirin provides not the least of which is it seems to prevent some forms of cancer. Yeah cancer is a big one It might slow or even prevent Dementia onset They shown there's a there is some evidence that it reduces mortality for women that are high risk for pre-clampsia which is a sort of a high blood pressure thing that happens to pregnant women. Yeah so yeah they're just now and like you said there's been more studies about aspirin like any other medicine in it. They haven't stopped because they're still discovering things like this. Yeah they so a specific kinds of cancer colorectal. Cancer is the one that that people benefit from the most. At least as far as we know right now there's one study that found a thirty eight percent decrease. this is a fourteen thousand person population. study Yeah population sample. Thirty eight percent reduction in the chances of getting colorectal cancer. If you took a daily aspirin regimen it's amazing it's not great though Like we said there the regular side effects like the bleeding and the stomach issues and potentially stomach bleeding They've also found that it suppresses immune response and they don't fully get that But they do think that. I think it's the low dose aspirin over I think the low dose aspirin is not hindering the immune response is really just the higher doses but they figured out. Well actually we can use this unlike graft operations organ transplants. You can give somebody aspirin and it will keep help. Keep the body from rejecting it. Yeah an amazing. Historically they have sort of look back now and said. I think all this heavy aspirin use might have hurt us. In the past with things like the nineteen eighteen flu pandemic The mortality rate could have increased. Because they were just like shoveling aspirin down those third throats. Yeah what else. There's a couple of other things Again there's that gi bleeding They found that If you already have a blood clotting disorder rabidly. Don't wanna take aspirin and read somewhere that Rasputin actually gained. Favor from the romanovs. From saving one of the romanoff kids lives who had hemophilia By saying like they needed to stop using any kind of modern medicine which included aspirin which probably saved the kid's life because it kept it from being kept the blood from thinning of In a kid that already had hemophilia and they they thought rasputin was a magical healer for that And then another thing. We should mention in the eighties and nineties They discovered that giving aspirin to kids really increase their chances of something called ray syndrome or ray syndrome r. e. y. e. I which causes brain swelling brain damage very often leads to death and there were. This was a big discovery and a lot of guidelines When in place where they all of sudden like kids using aspirin went down by ninety percent. Which at the time was With the increase of other insects really really put a hurting on aspirants market share. Yeah no they found that. If you cut the use of aspirin the rates of return syndrome and kids went down ninety percents of yeah so they were like stop using get. Stop giving your kids aspirin till it went down one hundred percent basically a and it was already like. You're saying i mean the other end says it cut into their markets here that one almost killed aspirin it was just that the heart protectiveness that brought it back yet. Another thing that almost killed Aspirin in buyer was After world war one they were bought out by g. Farben and If you know anything about i g farben that company they manufactured zyklon b very scary stuff but bear survived all that the dissolution of g farben eventually happened and they were able to kinda just say hey. That wasn't us. We weren't doing that. We're we're the good old fashioned aspirin and heroin people right exactly so Over the years. They've figured out like okay. There's still problems with aspirin that we we could stand to to still keep going like the whole gi bleeding. Things seems to be a problem so they've come with different formulations and Ed who helps us with this one turned up that there was at least one mentioned that they try to chocolate coating of aspirin delicious do but he couldn't find any other place that had that no but they did make the just easier to swallow and less bitter coated versions they did and let's not forget buffer remember buffering buffering. Buffering was an aspirin with a An an acid attached to it. Oh that's that was. It kept your your stomach from getting upset and apparently bear also came up with the version that had a coding so strong it survives your stomach and it. It dissolves in the gut where it's where it's it's absorbed us. Poop padilla totally useless. It's called bear useless aspirin. it's called corn. They counted you got anything else. Nothing else okay. Well since checks that he's got nothing else. And i said i got nothing else we're just both presuming the jerry's got nothing else. It's time for a listener mail This is from alex ramos about the bay of pigs movie. And by the way We should issue a quick. I had one too. But i know that you very much misspoke when you said roberto clemente was dishonorably discharged. Oh thank you yes. That was just a mouth error You we knew that. It was honorable. And i didn't catch it at the time either. So thanks for those for gins pittsburgh ins who wrote in yes and then there was one i did think. Oh yeah. Rabbits aren't rodents but rodents or rabbits. All right greetings from state college pennsylvania. guys started listening a couple of years ago to ease the pain monotony of scraping off old wallpaper in the house. My wife and i had just bought an abandoned devoted listener. Ever since listening to bay of pigs right now Head finished yet so may be jumping the gun. You're not you're amusing about making a movie. One day about the bay of pigs operation. I wanna let you know that there's sort of is. There's a coleman francis movie called red zone cuba that is partially about the bay of pigs operation and also for some reason about a tungsten mind with hidden treasure. It's a real snooze fest plotting and confusing which is why it was picked up by mystery science theater three thousand back in the day The film for derision. I'm a actually watched it then. If that's the case. I don't remember it though. I don't remember that one. Either i say in. Their commentary is great. Makes it watchable love the show. Keep it up also the off chance you read this on the air with money. Plugging my artwork. Of course alex will play your work. i'm a self taught painter mostly painting a realistic still like pieces in acrylic and my work can be found at alex. Dot ramos studio dot com. That is our am s very nice. Nice applaud. chuck. That was beautiful. It's good we don't plug stuff a lot but we love we. Love artists in people are out there trying to to scrape by here in this weird time. Yeah and i'm not seeing it right now when i just clicked it though i think i think just fall for phishing scam. I don't think so. I think i just went to rama studio in. Its alex dot ramos studio. Yeah we're going with ramos although either famous ramos. Alex from now on Well if you want to send us a confusing email or at least confusing with the confusing. Url we love those. Because let's try on air and then hilarity ensues. You can wrap it up. Spank it on the bottom. And send it off to stuff podcasts. At iheartradio dot com stuff. You should know is production of iheartradio for more podcast. Iheartradio is the iheartradio app apple podcasts. Or wherever you listen to your favorite shows. Holiday season means stocking up on some essentials like decorations and an ugly sweater with the bank of america. Cash rewards credit card. You can choose her in three percent cashback online shopping. The essentials have never felt more rewarding visit bank of america dot com slash more rewarding to apply now copyright two thousand twenty bank of america corporation as an educator. You've been leading students to grow learn and achieve for years. Take your passion to the next level by earning your doctoral degree in education online at grand canyon university become a change agent and help identify emerging trends in k twelve education develop innovative solutions and make measured improvements. What do you think making a difference in education. Looks like dc. You offers over one hundred. Seventy five high quality online programs like this one. Find your purpose at grand canyon university visit. Dcu dot edu.

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Ben Askren Retires From MMA Reaction | The A-Side Live Chat

The MMA Hour with Ariel Helwani

15:20 min | 1 year ago

Ben Askren Retires From MMA Reaction | The A-Side Live Chat

"Cantor from Cox has all your favorites all in one place and with the contour remote you can use your voice to fund them on live TV on demand and streaming APPs like like netflix video. And more see Cox dot com for details. What is up everyone Jose young sear with EMI FIGHTING DOT com impromptu episode of the aside live chat sitting next to me is Kaley my brother from the North in Toronto? Now Alex this is a very last minute episode. Like I said I call very last minute because we got some very last minute breaking breaking news and that is Ben. Aspirin has announced his retirement from mixed martial arts us on Airolo on his show or on. ESPN and officially hung up his four ounce gloves. So I'll put you on spot. What is your immediate reaction? After hearing the news I what are you expecting from one. Mr Ben Aspirin going forward well based on the comments. He made in his results in the Safar. So far I would say unsurprised unsurprised. The time is probably right if anything I respect that. He's probably that he's leaving when there's probably still no money to be made and I actually even though we're talking Hashtag may retirements. I actually think this is one that will stick forgetting for anyone who missed the the Hawaii show announcement he. He's I believe he needs to. He needs a hip replacement. That's probably it for you as a high level. ANIME fighter You you know. And he's he's thirty five years old. He's been involved in some form of combat sports since he was very very young so much wear and tear on his body so yeah unsurprising and I would also a welcome retirement. And that's I say that with respect to Tabet Aspirin. Yeah for anyone who's followed. aspirins career watched any interviews lately. I he's made. He's made it known that mix march was never his one true love he really loves the the world world of like amateur wrestling. Collegiate wrestling key coaches a lot kids. He coaches fighters coach Tyron Woodley. I coaches barber. He wasn't there for her last night but she made sure to give him a shout-out but Ben Aspirin retired with a record. I believe of eighteen and two If I'm not nineteen into his last two losses were the only two losses he ha- ever had he lost to hoard Maswadeh which everyone has heard or seen now special instagram in five seconds fascists knockout in I. UCF Street and then he gets submitted. By Day Maya so getting knocked out by Hori Mazda against submitted by Damian. Maya had nothing to hang your head down dame is arguably the greatest grappler blur and UFC history and corey. Boswell is the hottest fighter on the roster right now But a bearing those two losses aside what is going to be your lasting memory the From Ben Aspirin either inside the octagon outside the octagon any of the other plethora promotions He's fought under man. This is a guy for I mean I mean for the most part did things his way And you just got to respect that. I know it's a cliche but you certainly can't say about every fighter and I would say Aspirin Oscar. He's an original You know I'm not the biggest cleaned wrestling fan. But I know he was nicknamed Funky because his style was an orthodox so from his earliest super successful. NCW CHAMP EH days. He's had people kind of questioning how he goes about things so you know. He answered those questions in college. And then he gets in Tampa Bay and yes. He's very one dimensional but super successful missile rather the gate bell tower. Pick them up. He becomes a champion. He beats names like Douglas Lima Andrei Korsakov. People can say oh this was before they became you know before their there primes. Say What you want. We won't know because I've had a rematch. Those are wins on Bonanza Record He did it his way you know and instead of going to the AFC after he went to one championship mature. There's a spat with Dana White. Very public saying like Oh. I'd rather watch grass grow. I think it was referenced. been asking some Dana Whitey like that Really really questioning whether aspirin was entertaining enough to be in the sea. So I'll ask her and went did his thing finding one and then and then he made his way to the UFC anyway and in this last year made plenty of headlines. Uh Uh drew plenty of eyeballs and in pro wrestling parlance put over some people major especially Muslims that the hormonal thing doesn't happen without this aspirin viewed in an aspirin running into his knee via the I mean people have been saying ever since he lost Damian in Singapore main event. They've really been cause is remember Ben. Aspirin was traded for Dimitrios Johnson. That I think that's going to be one of his lasting legacy stu he was part of the first real trade between promotions Johnson left. USC IN EXCHANGE FOR BANANA CREAM CITY wanted to test himself against the best In my mind what stands out the most not his inside the inside the cage or octagon. But it's one he said like I might not be the best like I'm not gonNA. I might not retire undefeated but I at least want to try. I WANNA compete against the best. So he never walked around declaring himself. Like I am the greatest I on the greatest the greatest you want to try and he came to the AFC didn't work out and he said and he lost harbaugh's doll in five seconds handled. Donald loss better than most fighters would a decision loss. I mean he's he tweeted right away. He's like well that didn't go as planned. And then I heather. Hardy tweeted like everyone needs to stop picking on Bhaskar and this and that I've been asking like I deserve it. Don't worry about it so the way Ben. Aspirin handles defeat I think. A lot of young fighters can can really take from. I mean he said. I don't WanNa be like Ronda Rousey it happens the only thing we learned in that fight is horrid might as well has grainy and I'm not invincible. I can't can't that right. There just shows you kind of finer Ben asking is like he loses to the best and he owns up to it loses to Damian Maya and his interview backstage on. ESPN and goes. I just lost. Also the greatest submission artists arguably in the history of mixed martial arts so handles his losses very well was very dominant. I think people forget that he's he's it's like a record against Andrei Korsakov where he struggled like two hundred and something to like five in that fight you finish them and you finish. Finish them. Beat Douglas Lima. Who is it's either one eight one beat for people for Grace Fighter and Baladora history? Has the windows. Shinya Aoki has w over Robbie lawler say what you want about that by a w w just loses the two guys and calls career so I wish fighters I wish fans that really started to watch anime in. The last has two years like when the Rhonda's and the Connors everyone's rose. I wish they got to see him in his prime when he was not even tearing through people just like dominating like look. If you can't get up you can't get a groman off topic you shouldn't be champion. That's my mentality anyway but Yeah go ahead. I don't want to Romanticize is his style too much. Let's not I'm not gonNA pretend that pre UC BEN ASPIRIN DISA- Shogun esque. He was he was winning. He was not he was winning fights. I I'm I'm glad we did this because I wanNA bring one personal anecdote I was. I was in a glamorous Windsor Ontario when he fought Douglas Lima great crowd. Yes great crowd the card. Of course he was not very good and it was kept off by this aspirin fight where he held Lima down. And it's not asking Lima couldn't get up. The crowd became came so aggravated. I believe there was during this this twenty five minutes. There was two fights in the crowd so You know and those with maybe the most entertaining tonight so so regardless asking get to react and how to people sometimes it wasn't good sometimes style literally incited violence in those watching but again we can't discount that he was a winner at the end of the day and then regardless of his style managed to be an entertaining personality outside of the cage and that goes a long way chill. Sony Sony can tell you that she'll sewn in you know he had this exciting fights later but was known as very much a grind wrestler at your saint-pierre when most famous fighters of all time a lot of critics of his style L. But certainly Certainly a popular guy so aspirin is somewhere in that lineas that entertaining wrestler lineage. And certainly the sport is a little bit worse off for For his personality not being around. Yeah I mean his fights you saw them yourself when I was there on site for U. of C.. Two thirty nine for his fight against Horry Mazda. If you look at the numbers like John Jones is in the main event Amanda Nunez's Komen event. Holly Home Is there Luke. Rock hold like a young image based on that card. Who Do you think did the most numbers in terms terms of traffic and youtube views? Mister funky Mister Funky bad ass had a walmart sponsorship in that during that fight too so it just goes to show you that people do one. He spoke people listened. I remember vividly that first press conference. They introduced them to the AFC before his fight against Robbie lawler us all up on stage with all the fighters and he was going that everyone like he was talking to Kevin Lee. who was coming from? Welterweight talking booze man. He's tall he's calling on. Called COVINGTON is calling out everybody and then he goes does any quote unquote submits Robbie Law. I don't a win is a win like I said Robbie lawler handled his loss. Well too and then flies immediately. Because I'M GONNA be Robbie lawler and I'm GONNA fight the winner dance cancel Hormuz Law and then. We'll fight for the championship. This is a guy that when he said it normally came true. You didn't end up beating hurry module but you have to assume if he had he most certainly would have been finding for title right away I think especially dominant horry Mazi doll like that but if that doesn't happen we don't get a beam championship the world. We don't see we don't we don't get holy Lori Mazda all being the biggest star in the AFC right now so yes. In terms of wins and losses one change clearly came. Came out the better in that trade again. I think you said it perfectly. Without Ben Aspirin there is no what the last fifteen months twelve months of the. UFC has been wildly exciting. I think been asking and had a lot to do with that. Yeah you look you need. The world caused him to other become stars or to build other stars And I'm not saying that you have see has control over which one happens whether the fighter they signed become star are they building up but in this case it certainly worked out in billy another star and And I've joked online about you know how bad the trade looks but it's true you've got everything pretty much everything they wanted out of it. I guarantee they have pretty much zero regrets. Let's about making that trade so everyone should be happy. And I hope that Ben Aspirin finds happiness in moving onto wrestling coaching. And just being done with this this This nasty business of fighting and I will say everyone's GonNa question like was he a good fighter. was he a great fighter was he will beat her like he was an excellent prizefighter. And that's what this game is about is getting people to watch you fight and that is exactly what Ben asking. Just tell son-in-law is the whole argument jail sudden was good not great fighter Chill Sutton is a phenomenal prizefighter Ben. Aspirin is a phenomenal prizefighter. Like yes they might lose to people. But you're still watching that that those fights happen and you want you paying watch them lose or you want to see them win. Regardless everyone paid attention to Ben asking I really think the world makes Smart Lars is GonNa Miss GonNa Miss Him. I mean I was backstage at. UC Milwaukee which is the last ever Fox card and he was the guest fighter. And I was speaking so some of the AFC PR. I'm like what's it like. Like been working with Ben after like he's he's a new fighter and he's already doing gas fighter spas and they're all like he's great. He'll do any interview they'll do it for ten fifteen minutes and then we you were doing the scrum. Which you've done a million of guests fighter? scrums it's going like sixteen minutes and then the UC PR goes bad enough. Because I was having fun guys come on so it was like he wants to do that. Like how often do you get fighters that want to do media. You rarely get that any days. I mean you see Robbie Law. He's like I don't WanNa be here like fighters like back like nate diaz muzzle forty minutes. Late immediate a bashkir not only wants to do it. He'll talk to anybody and he'll talk to everybody so as a medium fan as a media member. I'm going to Miss Bennet Aspirin. Yeah for sure like I said from our perspective deputy and asset from the US's perspective asset. And I think history when he will look back on his career When we're out of this moment of got knocked on five seconds you've got some into my? I think history will very favorably on what asking accomplished as a fighter and he's not going anywhere still coach. Tyron Woodley I'm sure you're still the brothers. You coaches macy vibrant alley coaches a lot of those guys a up at Rufus sport so for his lasting legacy I think we I wish we had seen him fight. The George Saint. Pierre's the Roy McDonald's of the world the guys that he really wanted to fight at that time I remember when Carlos Condit was fired Joyce. CPI banishments. I'll fight the winner tomorrow so like I wish we had got to see but asking versus Joyce. NPR obviously I would favor Joyce NPR very heavily. But there's always that question out there that Ben Aspirin called for so long and we never got that fight but finally the fact the fact that you've been talking about it tells you what a persona this guy created for himself before coming to the with no with no not being the number one spot you know. He people that that reputation as hey. What would happen if you bought George saint-pierre that they were even asking talking is a credit to his Promo ability well I was GonNa ask you what your lasting legacy is but I'll go first my lasting legacy in my mind. Is that Ben asking. He was made it outside of the. They say Dana go to one world series of fighting. He said forget dads go to one championship. Make more money. So he is one of those rare fighters that had a following following before he even got to the quote Unquote Big Leagues as fans call the UFC Baladora one championship. It comes over and is a media inserted into the UH intellect but not not immediate shop like the top ten range and everyone wants to see screen talk or fight and he hasn't even stepped aside the octagon yet. So it's I can't think think of many other fires. Maybe if like I said one of the pit bull brothers or Douglas Lee more like if MVP forever comes over to the UFC or anyone other from one championship. I'm sure there's going to be a lot. There's a lot of the stars that if they do. We'll have the same thing but Ben Aspirin captivated audiences with his words and then they brought those fans into the octagon. That is what I'm GonNa Remember most about aspirin. Alex what is your lasting legacy in for bad. I mean you pretty much summed it up great points. I don't know if it's the crystals this new crystals thing which I'm against you seem more lucid and focus than it was very impressive and I'll just add. I hope I hope that fighters other fighters can sort of learn some stuff from from about aspirin and big how he built himself up. It really isn't about your style McCain who said many times he was not the most exciting guy in the cage. You could probably count like if you took his top top five fights I mean they. They don't stack up to a lot of other people's talking bibles exciting. That's just a fact but there's a lot to learn from how did what he did And it's not easy you know not. Everyone has his personality his background. His maybe some of the levers you might have had some fighters don't but there's definitely things to be learned and I hope The next generation of fighters kind of look at how he built himself up. And you know. Just take some things things here and there and and and it's not about being fake but it is about having your own persona and and trusting in it and and it can take you a long way. Well said Alex for Alex. This this is Jose this has been a very last minute impromptu. Quick episode of the live chat stick around on the Youtube page. And this and that We'll be back with a a a an actual live full at full length. Our episode of China Wednesday. I'm not gonNA tell you. The guest is yet This'll be up on like stitcher injures spotify. Google play all that fun stuff but for Alex. This is Jose we're up.

Aspirin Mr Ben Aspirin AFC UFC BEN ASPIRIN DISA- Shogun esque Robbie lawler Aspirin Oscar Damian Maya Alex Tyron Woodley wrestling ESPN Jose Robbie Law Douglas Lima Douglas Lima Andrei Korsakov Collegiate wrestling netflix Safar Dana White
Behind the Scenes Minis: Aspirin and Lalibela

Stuff You Missed in History Class

11:57 min | 1 year ago

Behind the Scenes Minis: Aspirin and Lalibela

"This episode disgrace that is brought to you by Amazon music. Hd a music streaming service with over fifty million songs in high definition and millions in ultra high definition when you stream on Amazon music hd you get more than double the standard streaming services so you can actually hear all the the music was recorded but the way the intended for you to hear maybe even while thinking about some of the stories. We told you that the didn't intend for you to hear so star listening now. With the free thirty eight trial of Amazon music. HD BY GOING TO AMAZON DOT COM in searching for Amazon music HD news automatically terms arms apply. When you need facetime with your boss? All you do is look in the mirror. non-national boss day you take yourself out to lunch and you never say things like synchronized energize because well. It sounds sounds ridiculous. You're a small business owner born to be your own boss and Amex can help with payment flexibility. So you can keep doing what you were made to do. The powerful backing of American Express. Don't do business without it. Terms apply learn more at American Express dot com slash business. Welcome to stuff. You missed history. Class A production of heart radios. How stuff works? Hello and welcome. Welcome to the PODCAST. I'm holly FRY and I'm Tracy Wilson and this is our Our what we're starting to refer to as casual Friday. Yeah our little Our little chat Yeah so I. We're GONNA talk about the invention of aspirin because I did not realize I had long heard the stories of willow bark being chewed chewed on by people in ancient times as a treatment for various maladies but I didn't realize One I Edward Leigh. I am not a chemist in my high school chemistry experience was Shall we say less than installer. The teacher was amazing but I really struggled with it and so like I think she kind of just kept like passing me along just out of kindness. Because she's like how he's never going to get excuse and she was amazing and my all of my best friends were really smart at it so I felt like just the stupidest person on earth but I I did not really understand that. Saxon and salicylic acid are two different things because in a lot of casual literature that is not like a peer reviewed scientific scientic journal thing. They get used completely interchangeably. Dah well and the thing that our listeners will not know because they will have all been removed from what we recorded I incorrectly call it sal. Silicon every time I needed to say the word and I had to see what we always run into words like that for both of us I feel like I. I think it's just probably a word that got in my head wrong at some point and sort of stuck there. Yeah I also. I was watching several chemistry videos Trying to kind of wrap my brain around it with mixed success and I kept marveling because sometimes the way that that chemists pronounce things are very different from the way I ever learned them and then I think probably these words are said so infrequently by the general public that nobody really we get to wadded up about Pronuncia since most of that work is happening on paper and is being documented rather than just just orally Shared by like in the scientific community. They probably don't get as as weird about it yet. Somehow that reminds me I was. I was taking some transit transit the other day and I'm not going to name any names because I don't WanNa throw any brands under the bus But there was just a billboard with a picture of the product and the name of the the product underneath it and then underneath that said it's pronounced and then a rendering over pronunciation that did not look like how you would say that and I was career why you got a name your product. Something that requires an explanation for how to pronounce. It is not intuitive based on how you spelled it I would so love to fly on the wall in that marketing discussion. Yeah we're you know there are some executive way up the food chain. That Lake just decided with the name and then they're all like well. How do we communicate this? We make it part of our brand Dan. He's eventually we. We're going to have to give a phonetic spelling and when when we were talking about where the name aspirin came from and how the other letters correlated with things and this the ending of I n being popular at the time I made me just sort of dwell in in my mind for a moment about like pharmaceutical naming today and how just bizarre and random some of it can seem like it. It does not like a lot of the things when when you're watching TV and you're seeing the ads for for drugs. Sometimes it's like did you just put letters into a hopper. pull him out. Wanted US out of this work I did. I didn't end up using it as a source but I did while working on this episode stumble across essentially like an article that was written and by I think it was two experts on drug naming in a lot of it was about like trying to separate yours from others and how sometimes that means means that you have to do some things that are counterintuitive. Is this how we get crazy medicine. It's like people are just trying to be different. I feel like this Reminds me this is a big leap but come with me of wedding dresses in the nineteen eighties where everyone wanted to wear white but also wanted to look very different so so some very crazy design started happening. I feel like it's kind of the same thing everybody wants to sound. Scientific reliable you know comes from a place of great knowledge but also different enough. And that's how you get. Some of the nutty brand names that we have for drugs is my guess. Some of them are pretty pretty far field. Yeah I'm certainly very grateful that we figured out this whole aspirin. I also didn't realize that like to make it more palatable palatable and there are still people we should be clear that even in its its most easily digestible form still can have trouble With their their their GI tract from it. And from anything you know different. People are going to be sensitive to different things. But I didn't realize that your body is like doing such a big lift in terms of converting it and from the stable thing that you could digest to the thing that actually delivers pain relief gay. Yeah I'm learning. I'm learning nope which is always the ideal so our second episode this week coming out on Christmas Day was on the raccoon churches in Ethiopia. The complex called called LALIBELA. And I said this is the end of the show but I want to say it again as I was working on this there were times that I thought I wish this were a video podcast which I don't really wish because because that is so much more labor involved than the podcast we currently have but man. It's hard to convey how amazing those churches ages were without looking at them. I say were there exists Yeah they're spectacularly beautiful and just Brain breaking in terms of like how they were built it in some of the pictures that you will see you will see folks sort of clustered around the edge of the rim of the trench that circles the churches just with their feet dangling over and I look at it and I'm like man I am terrified at the at the idea because when I was a kid I was really scared of heights and that was something that I was able to move through in my young adult. Don't years but still occasionally if I'm in a high place I get a little anxious about it and just seeing sort of the the people some of whom had come on pilgrimage to just sitting getting around the edge of this four story deep rock. Trench was I guess both inspiring and terrified. I can understand that I think I'm more freaked out by the people standing around it. If they're sitting I feel well. I think I would be able to sit there but I would not be able to stand and lean over and look down without panicking and probably causing my own fall. Yeah yeah sitting great though. Somehow that reminds me of when I was eight I was a youth. I don't remember exactly how old I was. But it was. When Halley's comet came through and my church that I was raised in Organized a little trip up to a local mountain top to look at the comet and and this kid who was about a year older than me was so anxious about the other kids who were Kinda up there playing because there were younger kids also and there there was a a hang gliding ramp and they're hanging around the edge of the ramp and he was just so terrified that he was about to witness a tragedy agitating so yet the other thing. That really struck me. When I was doing research about this was how aw colorful and vibrant this stories that were part of it? That are part of the Ethiopian Orthodox religious tradition. I really loved the imagery. Injury of of King Lalibela being surrounded by bees. Yeah and I also really loved the Whole Story About Mental Act the first go into visit Salomon Salomon and coming away with the Ark of the covenant. I kind of want to go see if I can find more accounts of how that might have gone down because because one of the things that I was listening to about it kind of described it as like that he was either given it or he just sort of removed it the intensive that being a little less clear and then as you said it It also reminded me of Indiana Jones as I I was working on that. Yeah don't Don't open that ARC. That's what I know. Yeah well it's treated in an incredibly sacred way All the ARCS are the story. Is that when the Ark of the Covenant was returned. It's been guarded by just one. Monk and a lot of the REPLICA ARCS. That are in the lally Bella Complex are similarly like they're in a part of the monastery only one person or a very select. Few people are even allowed into the area where it is kept so you can look at the UNESCO website for example they have lots and lots of pictures of what these churches look like. Stuffy missed in history classes the production of iheartradio's. How stuff works for more podcasts? For my heart radio. visit the iheartradio you Apple Apple podcasts. Or wherever you listen to your favorite shows. I'm Zoey Deutch. I'm Amanda CEO's Hey there I'm Bellamy let me young and today I'm GonNa talk about what I wore when I- auditions for scandal. Welcome to what I wear when production of Glamour and iheartradio. I'm your host Perry sabotaging each week. I'm sitting down with a woman. I find fascinating to talk about what she wore during a pivotal moment in her life. Listen to what I win on the iheartradio APP apple podcasts. Or wherever you get your podcasts.

Amazon aspirin iheartradio American Express Amex Apple ARC Zoey Deutch business owner Edward Leigh Pronuncia US Salomon Salomon King Lalibela Indiana lally Bella Complex UNESCO holly FRY
Episode 87 - June 1, 2019 AFP: American Family Physician

AFP: American Family Physician Podcast

26:54 min | 2 years ago

Episode 87 - June 1, 2019 AFP: American Family Physician

"The AFC podcast is sponsored by the American Academy of family physicians and by Quest Diagnostics, now offering a choice of ideology blood tests for Berkeley testing I-, GRE blood tests are well, suited for BC g vaccinated patients and for diagnosing latent, TB infections. Visit TB blood testing dot com to learn more. Welcome to the American family physician podcast for the June third twenty thousand nine addition. I'm kim. I'm jenna. I'm sean. I'm joe. We are residents and faculty today. Residents only from the university of Arizona college of medicine Phoenix family medicine. Residency this time on the podcast, we're going to talk about aspirin for the prevention of cardiovascular disease, anti coagulation for the treatment of vino thromboembolism in patients with cancer, varicose veins, adolescent substance use, and caregiver care. The opinions expressed in the podcast. Our own internet, represent the opinions of the American Academy of family, physicians the editor of American family, physician or banner health, do not use this podcast for medical advice. Instead sear own family doctor for medical care. All right. Residence, only no scripts. John's idea. No faculty. Nobody to call on for help. Yeah. Sounds great. Let's do it. We got this. All right. Can I up? We have an editorial rethinking aspirin for the primary prevention of cardiovascular disease from doctors, Lynn and Middleton. We know giving aspirin during a heart attack, or stroke can be licensing and the benefits of daily aspirin to prevent recurrent, cardiovascular disease, or also, well, established, but there is growing controversy regarding aspirins routine used for primary prevention so Kim. What makes us such a big deal? Well, according to some reports nearly one third of Americans forty years or older, take a daily aspirin. Many of whom have no known history of cardiovascular disease. That's a huge number it is. That's why you have the authors of this editorial and many others talking about this topic. There are real questions regarding the benefits of prevent. I heart attack or stroke versus the risks of bleeding. So how did we get here? The USPS currently recommends that adults fifty to fifty nine years of age start taking a daily low dose aspirin, if they have a cardiovascular risk greater than ten percent, and don't have bleeding risk factors. According to the guidelines, adults, sixty to sixty nine years of age with similar CD risk may be considered start low dose aspirin therapy, but or at a higher risk for bleeding and less likely to benefit overall. They found insufficient evidence this s the benefits and harms among adults younger than fifty and order than sixty nine right now. These are fairly recent guidelines based on a large number trial. So what's driving this current controversy? It may be hard to pinpoint exactly. But in twenty fourteen the FDA advised the general public against using aspirin therapy for primary prevention of heart attack or stroke, citing concerns about inside. Efficient evidence. Yeah, you have people arguing that findings of three. Recent studies are more supportive of the FDA recommendation than that of the US PS. Jeff one theory out there contends that fewer US adults are smoking, and more have become eligible for statins. An anti hypertensive in the decade or more since most trials analyzed by the US PS took place, which could have reduced aspirins benefit. Interesting. The arrived trial is one of the recent studies. It followed adults fifty five years or older with a moderate CD risk, or they were randomized to one hundred milligrams of aspirin daily or placebo, and followed for five years, and no difference between groups and cardiovascular death 'em is unstable angina stroke and TIA's. One percent of aspirin group, experienced GI bleeding compared with point five percent in the placebo group. Okay. Got it. You mentioned two additional studies. Right. Yeah. So that study of cardiovascular events in diabetes looked at diabetic adults in the UK and the aspirin in reducing events in the elderly trial, looked at community dwelling adults. Seventy years old were a meta analysis that pulled data from these three new studies with older primary prevention trials calculated a number needed to treat of two hundred sixty five to prevent cardiovascular outcome and a number needed to harm of two hundred ten to prevent a major bleeding event. Suggesting that aspirin provided. No nut benefit. Kim. You're painting, a pretty lousy picture for aspirin use in primary prevention. Is there anything we might be missing should be fair, Joe? This new data does not exclude, the possibility that Astrum may benefit adults, very high cardiovascular does. These risk or those at lower risk who are unable to tolerate statins. These studies also weren't designed to determine whether long-term daily aspirin reduces colorectal cancer incidence, or mortality as other evidence has suggestion in short. What are the authors saying here Kim? They argue that this new evidence should prompt, the US PS Tf to reevaluate, their twenty sixteen aspirin guideline, and that for most patients family docs, should focus on smoking. Cessation lifestyle changes controlling high blood pressure and prescribing. Statins as indicated to prevent heart attacks and strokes Kim. Thank you for that. Our next topic is a Cochran for clinicians anti coagulation for the long term treatment of vino thromboembolism in patients with cancer. This article comes to us from doctors Arnold Cooper Stein and Jonas, this Cochran for clinicians asked, what is the preferred anticoagulant? For long term prevention of recurring, Venus, thromboembolism or not, and patients with cancer. So patients with cancer have six times, the annual risk of ET. Oh, wow. Exactly. This is important to consider because as we know, cancer also increases risk of major bleeding. This can be significant for those patients with both cancer and. V T E. Let's take a look at the evidence. Sixteen RC tease involving about five thousand patients of all ages with cancer, both solid, Oregon in hematological with confirmed initial V T identified the primary outcome was all cause mortality, secondary outcomes, include recurrent, symptomatic, V, T, E and major bleeding interventions included. Low, molecular weight, heparin also known as Lova knocks vitamin k antagonists such as war friend, or direct oral anticoagulant dough axe like a pixel ban or river, rock Sabean, comparison of Lovenox to vitamin k and tag found. No difference in mortality. But Lovenox decrease recurrence of symptomatic V T E with a number needed to treat of nineteen and cancer patients without causing a difference in major bleeding. This is a strength of recommendation a based on consistent. Good quality evidence. Sounds pretty good. But what about the newer, anticoagulant skim well to doa showed no difference in all, cause mortality, recurrent, symptomatic, V, T, or major bleeding as compared to war, friend, and cancer patients, keep in mind. This is based on low quality data due to imprecise reporting, and inclusion criteria in these studies finally comparison, Lovenox Ando axe found no difference in all cause mortality dough X are as affective as Lova knocks invitee prevention, but at an increased risk of major bleeding with a number needed to harm of thirty four. This is a strength recognition be based on inconsistent or limited quality evidence guidelines from multiple organizations. Leading the American society of Clinical Oncology recommend Lovenox as first line treatment for recurrent. ET impatience with cancer, which is consistent with the result of this review. So you got it. The answer is Lovenox. And now we have varicose veins diagnosis and treatment from doctors rates Wilson and Collins from the university of Washington, family medicine, residency in Seattle, Washington varicose, veins are subcutaneous dilated veins, commonly seen in lower extremities, which are considered part of chronic venous disorders while the exact aetiology is unknown several underlying causes may contribute these include genetic predisposition incompetent valves. We can vascular walls and increased intravenous pressure known respect. Her is for developing varicose veins include family history of Venus disease, female sex older, age, pregnancy, obesity, chronic, constipation, and prolonged, standing many patients with varicose veins are a symptom Matic some localized symptoms patients may report include pain burning itching, and tingling more generalized symptoms such is aching heaviness cramping throbbing restlessness and. Swelling in the legs may also be present the presence of corona flip Tactica or fan shaped varicose veins, in the ankle is an early sign of advanced Venus disease diagnosis in evaluation is clinical, it's important to review patient risk factors symptoms and perform physical exam. If more severe disease, or interventional therapy is considered additional evaluation with Venus duplex ultrasound may be warranted. The C E A P classification system for chronic venous disease is helpful in the diagnosis of varicose veins. C A P stands for clinical ideological anatomic, and pathophysiology. Please see table, one in the article for review of classification system, treatment options include conservative management and interventional, therapies the decision to proceed with treatment and the choice of treatment are based on patient preferences and symptoms. Other considerations. Include cost insurance, reimbursement and the potential for complications, conservative treatment options such as compression, stockings leg elevation and lifestyle. Modifications may improve symptoms in some patients, compression stockings can provide really from discomfort. But evidence is lacking. Patients may ask about supplements for the treatment of varicose, veins flab, tonics are oral and topical therapies that are available is dietary supplements, they increase the vascular tone and may decrease symptoms of chronic, venous insufficiency, and these include flavonoids, or other compounds often extracted from plants keep in mind term data regarding safety, and effectiveness of flip a tonics are lacking, more recently thermal, ablation in Endo, Venus sclera therapy have become first line treatments. Thermal ablation using an external laser or via Endo, Venus, catheter with laser or radio. Frequency can destroy. Roy damage veins, and, and the Venus ablation is considered first line therapy in non pregnant patients. Endo Venus Clara therapy uses ultrasound guidance to inject superficial veins with an agent that causes inflammation of the endothelium resulting in fibrous and inclusion of the vein it can be used the treat small in medium, vans, or to treat recurrent, varicose veins. After surgery, surgery, historically, was the standard of care for the treatment of Eriko Spain's after the failure of conservative therapy, but recent literature does not support surgery as the best interventional treatment option up next is adolescent, substance, use and misuse recognition and management. This article is from doctors kulak and griswald from the state university of New York at buffalo. Well, this was great timing. I just spent the past few weeks. Working with our very own Luke Peterson in the addiction medicine program and no shocker here. Adolescent substance use has been. And still is huge problem in the US over the past decade, we've seen decreases in alcohol and traditional cigarette use among teens. But these gains have been offset by increases in the use of marijuana opioids and e cigarettes. Yeah. The types of products in ways in which they're used may vary. But this is an issue that cuts across socio economic and geographic lines a puts a big burden our families and communities, and we're talking about it today because family docs, are positioned to help exactly. And while the US PS has found insufficient evidence to assess the benefits and harms of screening for illicit drug use in Adelaide scence, as well as for primary care based behavior, interventions among this group. I think many of us still perform some form of screening during a heads assessments, definitely share deal. Yeah. Yeah. And if you're going to do it at all it probably makes sense to do it. Well, the American Academy of pediatrics recommends that clinicians become familiar with the s? Expert model. Are you familiar with this framework now? How about Cuban also now that was arcade game from the eighties. Feel me there. Okay. Well, s expert was developed by Samsa and stands for screening brief intervention and referral to treatment. Basically, if screening reveals a problem, a brief intervention is performed by the dock and referral for treatment is made as appropriate. Okay. So several validated screening tools can be used in the primary care setting with adolescence now. I plead guilty to not being as familiar as I should to these tolls. So I thought we could play a quick round of name that screening instrument to help acquaint, our listeners and ourselves. He has for let's do it. It's a great game. Okay. Yeah. Pretty popular. So I'm going to read questions from each screening tool. If you know what screening I'm using I want you to hit the buzzer and chime in no need the let me finish, John. If you get it, right. You get a point if you get it wrong you're out of the game. It's high stakes. Yeah. Exactly. Last thing you need at least one point to win. So no sitting back and just waiting for others to drop out our screening tool answers will be the craft questionnaire, the N I AAA screening guide the audit test, and the cage questionnaire. Here's the catch. One of those screening tools is not appropriate among adolescent use Ariel screening intervention tool. Number one, do you have any friends who drank beer, wine or any drink containing alcohol in the past year? How about in the past year on how many days have you had more than a few sips of beer wine or any drink containing alcohol? Incorrect. Kim you out of the game by Kim. Bye, guys and AAA God at Shawn. Okay. Yeah. So that was the anti AAA, it is from the National Institute on alcohol abuse and alcoholism and offers a quick to question age-specific screening regarding alcohol use for kids nine enough. That was a screen that was geared specifically towards middle school students. Okay. Kim's Al Jenna, Sean ready for the next screening instrument. Oh man ready? Here we go screening instrument. Number two, part. A during the past twelve months, did you drink any alcohol smoked? Any marijuana use anything else to get high part Bs craft that is correct? I'm gonna just finish the screen. So folks at home can listen to it. So part B says, have you ever ridden in a car driven by someone including yourself, who was high or had been using alcohol or? Drugs. Did you ever use alcohol or drugs to relax feel better about yourself or fit in? Did you ever use alcohol drugs while you are by yourself or alone? Do you ever forget things you did while using alcohol or drugs to your family or friends ever tell you that you should cut down on your drinking or drug use have you ever gotten in trouble while using alcohol or drugs? So yet that was the craft tool, it's recommended by the AARP's bright future guidelines, which many rescues it's designed to identify substance use as well substance related driving risk, and has been well, studied across diverse socioeconomic and racial backgrounds final screening instrument. How often do you have a drink containing alcohol? How many standard drinks cage in Kuranda Sean, you're out of the game? I win by default in the answer of this was, I got Jenna, let me finish it up. How many standard drinks can? -taining alcohol. You have on a typical day. How often do you have six or more drinks on one occasion? That was as genocide the audit, and actually a modified version, the audit C, which is eight three question. Screening modified from the initial ten question alcohol. Use disorder identification tests developed by the World Health Organization, it can be used in kids thirteen and up, as well as college students and interesting to note the cage questionnaire that Sean answered is the one that I remember learning in med school. And maybe others as well, but it's not recommended for use in Adelaide. It's good to know so congratulations that Jenna for winning the name that screening intervention game Tyler tell Jenna, which is one Jenner. You've just one eternal podcast screening question bragging rights. That's it. Wow. I'm honored keep in mind. Self administered screening may be valid in time, efficient, alternative to in in-person screening. If a screening test is positive doc should provide brief interventions using components of motivational interviewing what might that look like Jenna, AP, thin invention could be as simple as asking, what does alcohol slash heroin slash teats. He do for you and actively listening to the response, then you could ask I wonder if there's anything about that, that you don't like after read, you could summarize response and end with. So where does that leave? You got it. And based on this discussion providers determine the need for referral. I asking patient, if it's okay, the follow up at future visits confidentiality is a big part of these discussions. I know many of us were trained in the so-called split, visit model in which parents participate in the clinical visit for a limited time and then leave the room, the old friendly boot. Yeah. Exac. Sean, and this motto is supported by the AFP and most parents express understanding when the rationales discussed. So I hope this gives folks, a framework to consider using regarding this difficult topic. Our last topic is caregiver care coming to us from doctors swertz and Collins from Thomas Jefferson university. Did you know that eighty percent of adults requiring long-term care are currently living at home in the community and unpaid family caregivers are providing ninety percent of their care? I mean it makes sense, but I never really took the time to think about the size of that population. These folks provide service estimated to equal four hundred seventy billion dollars nationwide in twenty thirteen and demand for family. Caregivers is only expected to increase as we estimate by twenty thirty one in five adults will be sixty five years or older, and a significant number of these adults will need assistance with activities of daily living, or instrumental activities of daily living cell, how are we doing at supporting our family caregivers? Well, not great. This popular. Has been referred to as an invisible and isolated army and supporting them has emerged as a national public health priority while there are several benefits associated with carrying such as personal satisfaction, and relieving, another's discomfort feeling useful and needed and finding meaning in life caregiving, definitely involves significant stress and burden financial burden goes, well beyond the direct costs of care. Think about absenteeism and reduced work hours loss of promotions and training opportunities loss of salary or benefits and the result in a reduction in retirement, and social security benefit. There are also negative health effects for the caregivers caregiving has actually been associated with higher inflammatory burden in caretakers of demented, patients, insomnia, and depression, high-risk of serious illness increased mortality for spousal, caregivers, and these people are less likely to engage in their own preventive care. Many caregivers have a lack of information about caring for. Recipient safety and activities of daily living. They've also got a lack of information on self-care coping with stress and finding time for self icy caretakers all the time. But I never really took the time to think through all the difficulty they go through. I never really knew what to do to help these people either. So it's great to go through some of the advice, this article offers. Yeah, exactly. I feel the same way. So I provide an initial Sussman as soon as person self identifies as a caregiver offer repeat assessments as conditions change. There are great tools to help with this found in the article like the caregiver assessment table or caregiver strain index next support the caregiver this article suggests practical, an individualized approach to assistant caregivers encourage caregivers to take a break joint support groups and pursue their own interests. Also encourage them to take care of their own health in preventative care in seek respite care when needed. Family of vision should also provide accurate and disease, specific education resources. There are great online tool kit, such as AARP's prepare to care. We can provide education on performing medical tasks and referrals for healthcare needs such as nursing therapists elder care, agency's home health, adult day, programs and meal delivery encouraged caregivers to participate in the healthcare of recipients, caregivers our allies. And when the recipient and caregiver are treated as a diet outcome for both people are improved, their strong evidence that early palliative care interventions for patients with serious illness, improved quality of life, and family satisfaction. And can reduce caregiver burnout family physicians have a unique position to provide primary palliative care, including facilitating goals of care, discussions, advanced care, planning and symptom management. There's also great interventions coming out to help such as websites and apps to help schedule tasks coordinate caregivers meal delivery. And appointments. Other technologies that can be helpful include wearable and remote monitoring equipment in the home, smart home, technology and online interactive programs. Our caregivers are a huge population and they need support. I think for me I could see the burden of these people, but I wasn't prepared to assess for their needs and help them. It's great to have some guidance for assessment some practical areas, I can help. And this article provides a ton of resources to refer to for helping out our caregivers. And finally, where do you listen to the AFP podcast? Here's a note from some listeners. Those visit but a CD has enough data going, make it go mail. No, deb. Murga Mola e also, John. Buoy emai- Yemo than Aragon Aragon, your witness to the enter the quad at the medicine at the university of Texas medical branch in Galveston, y'all soy, Dakota at the billings, especially STAN sin family out of the Texas Tech University Health sciences center, one day each week. We wake up every morning, very early pack are sack lunch and at six forty five star. Ninety mile drive one way from alpine. Texas to procedure Texas owned the this amount of knows live on Thomas Tim Parana impact muss, no, less Thron web. So he see it. They mental skis that I'm young and they see almost no s little reacted in me as the alpine at Presidio, Texas, Presidio is aboard a ton of about seven thousand people. Most of whom are Spanish speaking, there without access to a full time position, no pharmacy in Heflin, ambulance, within ears hospital, emergency room being ninety miles away. As we ourselves from the city and lose radio signal. We start the af podcast and actively listen, as we look onto the beautiful scenery of west Texas, time after time the AFP podcast has proven practical and relevant to the care. We provide. Thank you for enabling us to improve our care to this vulnerable community. If you're looking to work with a special community, there, many places such as procedure that are need of a family physician. Soy meal Aragon that they has, but month on his own career, 'electronic, I if it be podcast out over, I if it wouldn't all eighty hey for Monday, no school tweet at ova. I if a podcast, but for security awareness, and I tunes, Mr. keyboard their podcast as Sean Abreu, Jake Anderson, Steve Brown. Jenna, Buchanan, Sarah, Coles. Kim Koi K E Joe's Yuba, Mr. Gutu technical either. So needle is Tyler Coles mister car for excreta eager battle. But doctorates Espacio elisa's in medicine familiar, Bill dabs Ryan Evans. He Justin Jenkins esta podcast foot Radel our status, Florida dentists, ethical dot the dot the Arizona, cola here in this enough Phoenix, but I see thence yet they made these enough media outlet. Was put on dog in this proximity. See on the American family physician podcast.

aspirin Kim Koi cancer US cardiovascular disease Al Jenna American family physician John Sean Abreu thromboembolism American Academy of family AARP marijuana Quest Diagnostics university of Arizona college FDA Texas Tyler Coles USPS
138: Still Life with Aspirin

The Slowdown

05:00 min | 2 years ago

138: Still Life with Aspirin

"I'm Tracy k Smith. And this is the slowdown. I've mentioned before that. The late Lucie Brock Brueghel was a remarkable poet and inspiring teacher. She was a truly inimitable presence, downright other worldly yet. Also somehow down to earth, highly dramatic yet. Also, exuberantly playful, language was for her a kind of fantasy kingdom wherein the realist of feelings, and most urgent of wishes could be realized today's poem is Brock brokos still life with aspirin, which describes visitation from the speakers deceased mother. But this spirit apparition doesn't feel like an ominous figure has come back to startle. The speaker, the way say the ghost of hamlet's father does in Brock brokos poem. The speaker is not frightened, but electrified. And in coming face to face with her lost loved one she almost seems to have been transported to the beyond herself what she calls ever with its rich and at times peculiar language the poem is dazzling. It's also conversational as if the speaker has composed herself just enough to pick up the phone and say to a close friend. You'll never believe what just happened to me. In fact, Lucy used to say poems were like that. Like someone reaching out to say come here, let me tell you what it was like. Still life with aspirin by Lucie Brock bright. Oh, there she was the mother of me like a lit- plinth heavenly, though. I was reared defined this kind of visitation impractical. She was an unbearable detail of the supreme celestial map of which I had been taught that there was no such thing Stevens wrote that for a poem to be true. It must come from an ever, if you don't fathom that, then you should not be reading this. I was there at ever, and it was mostly poignant, and it was cruel. It was a subjunctive place where touch with so particular it hurt like veterinarians deep kiss, like Jerusalem somewhere between fantasy and imagination. I was the procuress and the Gallow glass guarding the history and turf of everything intimate. What word would you use to describe me now? Imperishable imperishable, the stars appear every night in the sky. All is not well, all deepens v told me that all deepens, which is to say nothing like a mild, analgesic, which is to say, everything, like Lear's three girls, which is to say, all of my objects have lost their correlative states and you wanna know why? Because things are just things now just as everyone said they would be. When I was there at ever, by the way, I was an ascetic and quite vernacular. The land. There was all as peaceful as an aspirin, as the West Bank is any ternal circle of chalk, and brews and war. You did not dream. I held political ideals. Did you, you should not be reading this, and our remember me in the blows Z humid corridors beneath the Wailing Wall, most sacred place of all remember me wishing specific marooned as one who knew exactly what the ever was, and is a velvet school of courtesan, a gallows bird, all deep all deepening. The slowdown is a production of American public media in partnership with the library of congress and the poetry foundation.

aspirin Lucie Brock Brueghel Brock brokos Lucie Brock Tracy k Smith Wailing Wall congress Lucy West Bank Stevens Lear
UFC 244: Is Jorge Masvidal the Baddest Man in MMA?

ESPN Daily

18:41 min | 1 year ago

UFC 244: Is Jorge Masvidal the Baddest Man in MMA?

"These guys just flapping gums at each other any chance Sir is the fastest knockout in UFC history it took just five seconds for for him how a journeyman fighter became an overnight sensation it's Friday six at UFC two thirty nine that was a brutal brutal knockout you have to forces of gravity one is violent is a violent is definitely the right word I don't know if I'm sure that there may be some better ones but it was just I'm coming for that bell for so Dang long without really getting a ton of you Dan has something like that and you knew right away you recognize it immediately it caught lightning in a bottle and now he just knocked out Ben Aspirin and five seconds this dude is about to get paid I mean he's got a great sense of humor I got a separate myself from the pack and the only way to do that unity and it's his time to share with people who is he he's he is aware that he has a good story very proud of that he is Miami through and through his father immigrated here Selby's out of their apartment building he had memories as a child of her sitting up at night putting that he was he was in daycare and and he'd get into fights and that starts the fight but he's always willing to to be in the fight so if a they had to know what the consequences were and he would go after them now I'm envisioning Dana White Scouting daycares positive Whore has memories as young I will say is that he has real memories of he was like five or six was because when he was four his father was arrested he would stay in prison for the next eighteen years did he visit his dad uh he was traveling a little world and see like army moves on all these guys get money I'm like that is actually a an adjective that used to describe himself and when he was is like your dad he's an army what's the big deal goes no he started visiting his father regularly I mean he he said that he he missed his father nations like now the relationship is very cute it's it's it's it's very close him doing this he would go to the prison until his dad like this is what I'm GonNa do it my life you know not and you're going to be great at it and I support you one hundred percent how did Hor- hey get into you know he was he was getting in these fights in St essentially I was alone

UFC bell Dan Ben Aspirin Selby Dana White five seconds one hundred percent eighteen years
Ben Askren, Jake Paul

Five Rounds with Brett Okamoto

59:18 min | 6 months ago

Ben Askren, Jake Paul

"Hello friends it's your old pal area. Hawaii back with another exciting edition of the hawaii show pod and as you know the ufc off this weekend. A rare off weekend for the ultimate fighting championship but we hear the hawaii show. We told stop. We keep going till the break of dawn. Big news on tuesday. Jake paul ben aspirin. They're actually going to find a boxing match on april seventeenth. More on that in a moment but i do wanna shout out the one and only being comparable the inimitable stephen a smith and his new show on espn plus platform that challenge built. It's called stephen as world than it's full of his legendary hot takes and interviews with some of the biggest names in sports if that sounds like something you're interested in just visit. Espn plus dot com for more details and on top of that. There's a brand new. He has pm podcasts. I encourage all of you to check out. It's called i. Hey her take. It's a great show. I highly recommend it all right. Get that wherever you get your podcast. And of course was discretion is advised. Enjoy and gentlemen. Welcome to him back in your life on this wednesday january twenty seven. Two thousand and twenty one logan. Everyone welcome back to a brand new edition of the hawan show presented by draft kings. America's top rated daily fantasy app. And yes. my friends. I know were a little late on this wednesday. There's a reason for that. I will explain that reason at a later date. I promise you. There is a very good reason for that at all will make sense but we are here. No use in crying over spilt milk. Got a lot to get to. Of course you have. C two fifty seven in the rear view mirror. Conor mcgregor loses dust. Emporia on monday with dc. We talked about where destined goes from here where connor goes from here. Where does gay chief it. In and habib and nathan tony ferguson and dan hooker and rda mean who could forget the now infamous no pad that Has already been a requested by the Hall of fame that does not exist. And everyone's doing memes about akilah harrison all the stuff but on tuesday. We got some breaking news. I broke the news. tuesday morning. The jake paul. The problem child. Everyone's favorite boxer isn't going to box ben aspirin on april seventeenth parts. Unknown ten ounce gloves eight round fight twenty twenty cage ring. I keep saying cage. It's interesting it's a boxing match. Ben aspirins. I pro boxing match third pro boxing. Match for jake paul. The younger brother of logan paul one knows in amateur by the way coming off the big win over nate robinson this has turned the entire combat sports world upside down. Everyone's like How could you pick ben aspirin. He can strike. He was knocked out by hori mazda. Why don't you pick that. I wanted you big this guy but now you've got the anime media covering this. You got the fans talking about it. You got 'em fighters. This has now become jake. Paul versus ever. May he called the in my interview with him that you'll hear in a moment. He he called mma a brawl and not an art which is funny. Because of course it's called me yards. I mean he's playing this perfectly in everyone's eating it up hook line and sinker and so he picks an aspirin as his guy. Thirty six years old is coming off hip replacement surgery who retired from the ufc. They gave him permission to do this. Fight and everyone thinks that ben astrium is gonna get smoked. But excuse me. excuse me. Have we forgotten that ben. Aspirin is a two time national champion. We've gone that. He's a two time. Dan hodge trophy winner. Have we forgotten that. He's a two thousand eight olympian. Have we forgotten that. He's a one championship. Champion of bill. Tour champion. I mean yes. You can sail. You want about striking. But let's not forget that this is tough. This guy's a fighter. He took a knee to the dome by maswadeh that would have knocked anyone including a horse out chill out on the ben aspirin disrespect so today on the program we are going to hear from Nasrin about the making of this fight and wise taking this fight in his confidence going into the fight. And we'll also hear from jake. Paul my first time ever talking to jake paul and after say i enjoyed the conversation for the most part. Yeah he says. I'm kooky things. But he's a smart young man. Who knows how to promote himself. And there's a lot of fighters out there who could learn a thing or two from jake. Paul i though funky one ben aspirin enjoy. Let me ask you. When did the talks to fight. Jake paul in a boxing match begin. How did this happen. Yeah So it was actually two years. Go to attorney all through. Remember his november twenty team or twenty twenty one right now well. He thought that box he thought that basketball player. Unlike that week he was saying he wants to fight me. And i'm white sit on the college do nothing and Okay so then later some of their people out at all while. I'm just saying a bunch of names. You know like some people do sometimes and there were serious so then it's like okay. I had actually started working out a couple of weeks prior. Because you're right. Hip surgery couldn't do anything. I got over wakes. I love to eat. And i'm like. Hey i probably should start working out because i don't want to be fat and and you know i know myself. Here's myself. I have to actually like have a reason to not eat ice cream in diet so i was actually planning gonna do some wrestling matches. Maybe at some point this year of just to be competitive. I enjoy competing in this came up and it seems like the perfect opportunity for me The guy's not really a boxer or fighter at all. he's a youtube star. They offered me a bunch of money. And i'm excited to do it. Okay so when you were offered the opportunity to do this Was there any kind of like basically. It seemed like everyone was going after him right. It seemed like he had options. Those dylan dennis out there. There were other pro athletes. Why did they pick you because it seemed like. He had the pick of the litter right. Well i am a marquee name. Obviously ariel the slow bitch. I think he's legit scared. Paul like that is. I can't prove that. I had no proof for you but just just a field. I'm pretty good at getting feelings. Situations like feeling is like yes. Jake paul actually wanted to fight dylan because he really bitch adila. Dana's actually scared jake. Paul that's legitimately a not asking with you. So i do think i was second. Pick take his 'cause dylan right now. Is claiming online. That jake ran away from him. There's complete from my understanding the situation that is completely untrue so his people reached out. I said sure. I'll do it. I i don't care right. It seems like a fun. Time to me And that's why like. I don't understand why would been asking do this. And i've said this before. But when i was in high school you grew up in canada. I haven't you like with boxing gloves in my house and every once in a while you know with me and my buddies border friday night it was like hey. Let's go back to bed house and live box each other like that. Have you know dumb high school stuff you fight you fight you and we called it a good time so when they asked me to but it's not like a boxer. Mike tyson not going to box roy. Jones yeah will be. If i about those do the i'll be genuinely worry. I would be nervous or maybe another good guy. I'd be i'd be like even by the bite like a boxing met some of these guys i I stepped in a cage. Trained killers like guys. Who did this for a living. Jake paul is it youtube star. He was beat up two guys who have literally never been in a fight before their lives like the notion that this guy's good boxing is delusional. Now i understand you were still under contract with ufc. So did you have to get permission to do this. Yeah i've been. I've been in talks them. They've given me permission. They didn't really see a huge issue with it and our video. That is nice to hear now is the case. Where like connor fights floyd mayweather. They're getting a cut of the pay per view. Or is this all you zone me Did did that really happen. I'm not sure or they got they. Yeah they made money off that fun have proven because i thought that was like conspiracy theory using they were just walking around happy to take part no of course. They had to take part in the cut of the whole the whole pot. Yes i am sure about that. Okay all right this conspiracy. That's that's good business on their part right. They had to give connor permission to do this. It was gonna make a lot of money. You should be happy that they're not taking money. I appreciate that you see. Thank you very much okay. So that's one question that i think a lot of people are wondering the other one is. How could you box how you compete. How could you train after coming off. Hip replacement surgery which you had an aug correct. Yeah so uh septembers so okay. This is funny. So guy John wayne part that years of course for good for good So he had the exact same show dry had and i followed this. I think he did it. Maybe two or three months before me. i'm not. I'm not sure that date and i'm watching this train on instagram. You know. I'm like dude like he's going full go so i cheered up irish out. I said dude. Are you like. are you going full. Go because my doctor told me. I shouldn't go for a year as a. Yeah i don three months out and they said unclear to go anything i want. I could do a. He's going to do a real fight. You know like mixed martial arts or mu. As i said yeah. My doctor gave me full. Go after three months so i got this and i'm like wait. Why am i waiting a year. This is crap. And and i called. My doctor assisted. Or whatever and i said. Hey man this guy's this guy's good after three months. Why do i have to wait a whole year. And he said he said well listen that guy's rates of failure or whatever are lower than my are higher than mine. The doctor right as what. You're ready to failure. And he says one thousand one thousand as well. That's not very high rate. So so. I'm like i'm like good to trainees like well. We wouldn't advise. And i said well man that dude going full goal unlike maybe will go full out wrestling like next week or not them. But i'm i'm going to start working out and everything and so i started working out and Do it's better than before. I mean live. I would've known known what the outcome of the surgery was gonna be. And how i felt i would have done it after the first time a retired. Well yeah it's it's like so much. Better i mean i'd allowed back pain and i did not think the hip really atheist do with like i knew it was like on this side by didn't think had do the full back pain like back. Pain is gone. everything is a lot better. i sleep much better. everything's good. what about mobility. You're boxing result so much better. You don't feel restricted at. Do i feel so much better. While in k. Yeah not even close like i was did work out yesterday on the rowing machine and i was hitting numbers. I'd never hit before. It was ludwig's my range of motion. This is way different than it was when before. What i couldn't hit was restricted. I dislike really bad rain emotions on things and now i'm like so much better Have you ever had a boxing match. I know you haven't had a pro boxing match. But i've ever done an amateur fight a smoke any kind of boxing match before no. I'm not a do you have a so in the smoker. He wants to like in the gym. Yes there's days at welded dukes. Where he said are boxing today. Just boxing rounds or kickboxing today. Just kickboxing rounds like play those days. You want to count that. Who will be your corner on actually threatening to go sit down with duke and kinda like hash out a training plan kind of put a team in camp together And not entirely. Sure yet how it's gonna work out but missed out Plan will he be part of your team. All i wanna say i think he might be calling else. Said they don't quote me on that. Oh come but he will very likely be a part of my camping in some way shape or form Obviously i didn't even sign the deal to like two days ago so i started trading and getting in shape. It's trade again shape then when it got like a little more serious. I'd like turned up the training little bit where out started to every single day and i certainly do my strength conditioning coach again but we didn't really like have this finalized to until like two days ago and they were throwing around dates. That were much earlier than april seventeenth. So actually i feel like twelve weeks twelve weeks from right now as a long time and i'm in relative good shape already so yeah i feel really good about it. This is a fight that was put together by the trigger. Fight club team. He's a chiller fighter. Do you think they picked you because they think that he is going to beat you very convincingly gonna knock you out you're going to be another highlight reel this part of the progression in his career. He went from youtube guy the nba guy to now fighter. Do you think you were picked. Because they think that you're an easy fight. I mean there's probably one of the easy fight but easier. Who of a real fighter. Yeah there's probably not belief him in my standup which i listened with that a day I was never trying to be a great stint fighter mixed martial arts. I'm trying to be a great fighter. I took people down. Beat him up. Nineteen time it'd be getting my nineteen fights trier to george took every single person down almost at almost every single round. There was two rounds of a big about fifty or so writing. Take down against. There's two hundred iran down. So i was very very highly effective in my strategy of i've also never sides mas it all. Unfortunately i've never been knocked down. I'd never even been rocked. Nothing ever happened. So i'm highly efficient. Not getting it as well And that's again with a wider. Plethora of strikes. You can elbow meat kick me niimi punch me whatever martial arts and none of those trained killers were able to hit very hard whatsoever so we reported this a couple of hours ago and i've looked at some of the comments and especially from your fellow fighters in the majority of them are counting you out there saying this isn't embarrassment that ben is going to get knocked out there picking an easy fight and this is will blows me away and i would love to get your your take on it as you said nineteen an oh you started your career. This notion that ben asking i covered the majority of your my career as dominant fighter as there was m a right and then of course the buzzer. I'll fight happens and now the whole the whole history of your career has been changed to where all of a sudden. You're like this easy out. Does that not piss you off. That of it has to do with me. How does it bother you. It's great quote this morning. You wanna hear this great quote and on my podcast. I was on. I mentioned That a lot of people. Wisconsin seem white cut it to not let their distaste for iraj irs. And the one guys actually. He's not from wisconsin. agreement patterns fan and aaron rodgers. Had i guess he has a saying kill with indifference. And i thought that was interesting because i always feel like that's how i am with twitter's you don't read the comments you can't think about what people are saying because really in the big picture. It's it's relatively irrelevant and so if you look at My fight or prior to go to the afc. It was always this and it doesn't like you always never really fought anyone. Oh would leave when he beat lima. Lima was not good or was young. Or whatever bullshit right so it's always. There's always this notion that human beings and this is this could be one at discount other people right And so yeah. I mean i one bed fight against george. I never made the i was. I was not in good shape that entire year because of my hip i never was a little bitch. I didn't make excuses about it an to me. It is relevant. I chose to compete on circumstances. That's where i competed under. But the notion that by fire emma maker like i'd douglas lima five hours zero. None of which. We're all that competitive. Douglas lima is a really really high level guy. I would use that good. Fight him that simple. Everyone wants to fight this guy in the fight game. They want to shut him up. Do you feel like you're doing this on behalf of the fighting community the community is this. Mma versus boxing. Is this fighting versus youtube. Are you taking that on your shoulders. Nine the community. You know what. I what i what i would say about this. As you know everyone who's led to real fighter they understand. And this is whether like i would even consider like wrestlers fighters or ju maybe jitsu right any else say combat at the they understand what. It's like to really be a fighter. They understand what it's like to go. Through hard circumstances anton battled adversity deal with it. They understand that thing. That toughness j. Paul is a little bitch boy. He is some rich celebrity. Who wants to pretend. He is a fighter by fighting guys. Who are really bad. I mean jake was it. Last vessel players name robinson thing they robinson and the other rony i watched. I never watched it by watching it last night. It was really bad really really. It was not good era. Like you might have done just as well as that guy But so he has his no. She wants to be a fighter. It's almost embarrassing to real fighters like it's embarrassing to guys who actually been in a cage or they've been in a battle even united wrestling or jujitsu like those type of people it embarrassing. This guy is parading rally. He's actually a real fighter objectively though you can't give him any kind of credit like it does seem like he has For two zero fighter. No like i mean. He doesn't look like a guy who's a fish out of water you. you can't give them some credit will. How can you know. I i i really. Can't i find it very difficult to do. So how can you give him credit. When he's fighting guys who literally look at it never fought before you watch biting you and this other guy. Do you really think they've bought before any type of fine. No but you can tell when someone has proper technique. Red released knows what they're doing they're taking it. Sears good shape has a good team around. Like he's got a pro coaches and four hundred always in good shape. He fought one round. I mean you just look at the physique in that they need to shape spoken like someone who has had his physique criticized fair enough. It just looks like he's taking it seriously. No he's not out to make a mockery of the sport of boxing. Would you agree with that. Well you know what i think. He's he's out to make money which you know what. He the pulp. Rose pretty good that. But i've actually i've been thinking about this. The social media thing. I i think a lot of them report way more money than they actually make and you know really when your social media then all you have is supposed to be a star all you can do is put your social media but to actually create an event where you can make money in boxing. When it's things where you can be not very good at it and people are still interested in it you know and so willie robertson and the. I don't even know the other guy's name they and son gabe night s on. Give us another youtuber. Another uber they had literally never been a fight in their life. And so the notion that. We're going to give jake paul credit or say he's good. I guess the one thing. I would give him because he did. Hit those guys pretty hard now. They work very hard to hit because they'd never been in a fight before. What did he hit them. Pretty hard so. I'll give him that. Are you worried that if you get knocked out by him. This will change the narrative of your entire career. This will take away from the The dan hodge trophies the national championships. How is losing a by match. The eighth new college wrestling. That is insane. It just honestly it blows me away that people speak about you the way in which they do as a fighter like you deserve the your hall of famer in my opinion. I'm saying we have our jokes and stuff but you are the hall of famer. You're one of the best and most dominant fighters in the history of mixed martial arts and oh by the way kalija wrestling and by the way olympic wrestling they speak about you like some schlub off the corner of the streets going in there too. You're not a youtuber by this. No one knows your manager. For this i will. I will represent aaron rodgers quote earlier. Yeah kill them with the difference. Anyone who actually knows these sports does not feel that way about me. Okay and if they feel that way they do not understand wrestling and mixed martial arts and so highly different to their opinion. I am completely different but you know in this day and age means right. People make means the knockouts and other stuff. I you know. I've seen a couple of with george mazda at all so you're indifferent. Ask me different. How many wasn't guess. How many times. Epi mazda gift has been played. No i get it. I get a million a million plus so so he says he's gonna knock you out faster mazal response. How much are you making for this a lot of money. You're happy with it a very happy. More than you have see more than ever been paid for simplify. Wow well done. we'll go. you know. He makes it personal right. You know you saw some of the comments he made about. Connor made a personal. I don't know if you noticed this but I just noticed on instagram. He's only following two people now. Do you know who my wife probably shriller and your wife. My wife's outstanding lady. She's the. I know i've met well worth of all. She's lovely but are you worried about this. That he's gonna make it personal. No i'll be too high some youtube nerd like i give a shit what this guy fix. Have you ever met him. No no i. Don't i don't care i watched. I did watch a few videos at the first call me out is one of these things arab. Look i might be a boomer. Might be different jerry. I don't get out that. Oh by the way you're listening six. What were the same age thirty eight. I'm older than you. Okay listen so you get this. Was this old guy speaking. I don't understand why this guy's popular. I watch this stuff i was like. I don't get it like i. I understand what these teenagers seem like. He's not that funny. He doesn't seem particularly talented. Like i genuinely don't understand what people see him. Is this the beginning of a boxing career. Free electricity you not all this could open up a door to a whole new world. Listen okay liz this entire in a you can. You can play back the tape up. Sheriff said this. I have known attention to ever train to be a world champion in mixed martial arts for our again. If something interesting came up at some time maybe i would say yes. Okay but i will never be a fulltime fighter again. And i stick by that sub. The incident came up taking advantage of. That's something interesting. I it's to be fun. I'm looking forward to it being compensated. Well and That so do this. Will i say nothing will ever ever ever happen again after this. No i'm not saying that right. And what i am saying. I will never be a full-time fighter again. Can i tell you what would be really cool. Like a few. Bring all star corner you get. Dc out there you get chill audi said i'm gonna lose. Leave this guy. I was friend. Pc i can't believe you. Oh my gosh. he's tells me okay. Fair enough fair enough. So all right. So april seventeenth. It is official. And i think you can have a thing here. You see you don't wanna have like have a thing. I love what a podcast coaching wrestling match. Bitcoin it's going well and you buy bitcoin having to do with your life. Are you being paid in. Bitcoin is that true. Did you know what. I don't get this okay. Listen here's i don't understand that. I am being paid equality. I don't understand why people are quite because listen. I get a paycheck. If i were to go buy bitcoin and probably buy more. Bitcoin others buy some bitcoin. Like why do. I need to be paid in bitcoin. I don't need you. Like if i get a check and i wanna buy bitcoin up. Which in this case. I'll probably buys more others by it. I don't need to be paid. I don't get that one would be great boxing. You versus jake and then mma. He has a wrestling background. You know that right. I thought his brother russell. But i didn't think jake russell i think he did as well. Emma may not be better. That would be embarrassing. I'd be listed if you wanna give me free money. Sure yeah okay. Official prediction around seven round. Seven that late. Yeah because i don't have a huge amount of power. Take me some time to wear him down and making his life and you know eventually he's look. I'm orig- celebrity. Don't need to get fucking plunge more just going to roll over. Tko around seven. You're going to work the job. Go to the body a little bit. Do you think about. Maybe we should team up. I could teach you how lonnie boxing tips nerdy balls. Are you going to do it please. I think say you sent me. Bitcoin considerate okay. This is something it's it's a crazy thing. Something that was born on the internet. I guess it's apropos. Considering you know where where he comes. Apropos mian i dunno appropriate. It's appropriate guests kind of french term in any event You are officially fighting jake. Paul the most polarizing fighter in the world is he relates. People hate the guy because they feel like he wasn't. Why did they hate him. I don't get that either giveaways. He's insulting the sanctity of boxing. You know what's brilliant about this fight by the way the brilliance of this fight. Is you have the boxing. Fans who are all riled up because of his existence. Now you have the fans who are going to be interested because the media is going to cover it because of love you were the perfect guy in many respects your dentist and apparently you say they don't want the fight or doing such. Can you believe how much a little bit guys. And now he actually wants ankle. He wanted to fight like listen air. I will give you this and this is i. Don't want crap myself. I ll was number two. I was not in the driver seat. It was all it was. Dan is but dylan is actually scared of youtube star. That's so embarrassing. The the one thing. I do want to see i. I will admit i gotta facetime right before we did this from your old friend darren till and he's laughing. My friends take that back. He said you're going to get knocked out. And i said darren how could you. This is a member of the community. This is a this is a brother. it's a fraternity. And he said no way and he said you could tell them about to talk to. You said you could tell ben. I said that i'd like to see you. Get a little support from the enemy fighter gary jail. Now listen. i don't. I don't like them that much. They don't like me it's fine. I'm great all right. Good luck to you. Ben congrats on getting the fight. Thank you for the time you got piece we continue. I need all football fans out there to listen. At the moment you've been waiting for all season is right around the corner and draftkings the official daily fantasy partner of super bowl. Fifty five is bringing back their golden ticket giveaway with up to fifty five million dollars in prizes up for grabs. All you have to do to get your share of these. Huge prices is to enter the draftkings free super bowl predictions challenge. And once you submit your picks you will get a free instant prize up to twenty five thousand dollars and if you have the most predictions crack equal in the top prize of one million dollars. Download the app. Now enter the free prediction. Challenge answer questions like google score last and boom get ready. Draftkings paid over seven billion dollars to his players since two thousand twelve since they know a thing or two about big paydays. Download the draftkings right now. Use the promo code area to enter the free fifty. Five million dollars super bowl prediction challenge. Everyone gets an instant prize up to twenty five thousand dollars toward justifying so use. The promo code. Larry all right now and enter the free fifty five million dollars approach. Only a draft gains the official daily fantasy partner of super bowl fifty five terms and conditions and eligibility restrictions apply see draftkings dot com for details. Now let us say hello to the man who will be fighting. Ben aspirin on april seventeenth parts unknown. At least for now he is one of the most popular characters on the internet. The very polarizing the very controversial. Jake paul to know as a pro boxer one annoys an amateur. It just broke this morning. It's to be jake. Paul versus ben aspirin april seventeenth an eight round pro boxing match a ten ounce gloves. Twenty by twenty ring. All those things and more will be discussed right here and my first conversation with jake paul. It is nice to meet you sir. How are you good. Yo hearing like you're the first person i've like Like say it out loud. Let's go sounded really nice. April seventy then blows bro fight. Man is my first headlining event. And you're just hearing you say that malam excited will congratulations. So let me ask you. It did seem after the nate robinson. Fight that people were coming. After you had a lot of suitors you could have chosen a lot of people ultimately. Why did you choose. Ben aspirin as your next opponent. Yeah we were talking about five or six guys and an may fighter some celebrities an nfl guy and when it came down to the inc meeting the paper and then being green lighting this. Let's do this these guys. It turned out a lot of them. Were as serious as we thought i think. I think people don't like to give me props for my boxing ability but deep down they're like damn this kid. This kid can fight. And ben aspirin was really the only one who is serious about it and wanted to make it happen and was ready to go so kudos to him. But there guys like you dylan danis. I wanted to make that fight happened. He was all over social media. I through like muddy pissed filled toilet paper at his face. Like people wanted that flight. People wanted me to fight baskin. People wanted me to fight mcgregor. People wanted me to fight. All of those sites will happen eventually. But dana's blamed a knee injury. Conor mcgregor just loss eight. The as tied up by the ufc. Ben aspirin was really the only one ready to go. And let he's he has less losses than mcgregor. So he's a. He's a legit fighter who's finished twelve people in his professional career. And so for me. It's it's a perfect light because people wanna see me. Fight over a real fighter. They want they think that this youtube get is going to get knocked out by a real fighter. Did you pick ben aspirin. Because he was the easiest one to knock out. There are a lot of people whose He was knocked out in five seconds by horror. Mazda his standup isn't very good. Did you pick him because he was the easiest opponent. No i i think danis would be the easiest on it Aspirin has you know twenty something. Mma fights has been in with robbie. Lawler the tough. Tough guys I think anyone would have been knocked out by miles. Vidal's knee that need that landed was deadly anyone So i think dana's would have been the easiest fight by far. You know but these anime guys just because they throw punches doesn't mean they can box. This is why. I'm so confident. In my ability to the destroy these guys is because that no head movement they're slow. They aren't going to the gym. Every day and boxing throwing elbows kicks wrestling jujitsu. The list goes on. Boxing's our enemies a brawl. And that is why. I'm calling out all these people and you're gonna see we will see i say it. Every single time. I say in every single interview. I predict women. These people out. I predict what the media's gonna say i and you see one by one ben. Aspirin gets backed up. Dan it's knocked out is not doubt it's gonna happen people replay this interview and be like while the skit religious predicted. All of this shit. When will you knock them out. What's your prediction for this. You know i. I've been talking to my team about this. I'm i'm i'm to sharp right now and we're eighty two days away from the fight april seventeenth eighty two days. And you know just does this morning. I'm the. I'm too sharp on too fast. We wanted to be nice and say like hey you know it could go three rounds. He has a good chin. I just think by the end of this camp it. It'll end being a wanted to round fight. He he slow you know And my speed will immediately show and he will be getting hit from every single angle. And there's not much he can do and he's never been. He hasn't had a boxing match. So it's different than enemy you can't you can't just when when you when your heart and can't just shoot your little takedown. Ben can't do that buddy. Sorry he told me earlier. Today he predicts a seventh round. Tko of you. What's your response to that. My response is go. Google ben asking striking You know it's not gonna go that long it's not going to go. I don't i don't even think hit me. I haven't been hit one time in the face in my past two fights so i haven't even been punched as as a pro boxer. One time nate robinson landed one body shot in a clinch a i. I don't think baskin will even hit me. That's that's my prediction. So your response to that was go. Google ben aspirins striking. I see all the the gifts and all that stuff so include you. Don't respect to striking so then it goes back to the previous question. Why ben aspirin. Like i don't respect a lot of fighters strike gotcha. Okay even watching you know. He did a great job against mcgregor. but he's in. He's in south florida Poor areas and on putting this out. There i would love. I would love to spar you in in boxing. When when i see these guys stand game. They're just like i don't know it just doesn't it. It doesn't impress me a lot of these guys. So i i wanna go. Spa korea support. If you're watching this you know. Let's get in touch. Because i would love to set up a sparring session. You can help me out with my fight for aspirin. But i don't know. I was not impressed with these guys boxing. At all you mentioned dylan. Dana's he's been very vocal today. posting things online Dm's all that stuff saying that you ran away from him that he was ready to go. Can you clear the air. Would you have fought dylan. Dana's on seventeenth in other words. Why isn't dylan. Dana's your next opponent was the one that we were building towards. Yes so i. I put the biggest offer he's ever received on the table. How much seven figures okay. And we know he's probably getting fifty one hundred gay to fight and embellished with is the biggest offer. He lives at his mom's house. That's that's a fact like this guy lives with his mom and in new york somewhere in new jersey and he wanted so badly to fight in the summer i think because he wanted to train like have extra monster train because of his knee injury but that manager was over a year and a quarter like fifteen months ago. His knee injury. So i don't get how you still blame that plus. He's posting videos barring on on his instagram. And so we're talking to his manager out about the mcgregor fight and about the danis fight we show them the fifty million dollars per refunds for the mcgregor. Fight they kinda go silent than we're talking about the dance fight and they're like well we wanna do one. Mma one boxing. Dylan's big-name knows how to draw a crowd. But we have to do it in the summer because his injury. Guys the fights happening with or without dylan. We're not waiting till then. The fight is happening late march or april. That's what we told them with with the biggest offer they've ever received on the table and they're blaming they're blaming the injured i think dylan and i will fight eventually. Maybe not after sees what i do to to to. Ben i think legitimately dylan knows how good my hands are. And he's trawling he. He's you know commenting on shaky knows how to use social media when the rubber meets the road. This guy can't fuck em strike either. He's a fucking jujitsu at so He's capping off. I anyone you know. And and i've elicit people they're all gonna they're all gonna get crossed off eventually you referenced. The fifty million dollar offer to conor mcgregor. How close to that number is is been asking making on april seventeenth. Nowhere near that figures. I don't know. I can't say i can't say i don't wanna i don't wanna reveal contract details or anything like that but you know what about you. How much do stand to allow. More than the nate robinson. Fight a lot. That's all i mean. Look i not that. I had one of the most viral knockouts in history. And people. Say always cocky or he's boasting whatever that's just that's just a fact. Duda social media due to the wariness of it you know. I have grandma's coming up to me and being like oh. You're the one that knocked out. Nate robinson like everyone saw and that event did almost two million pay per view. Buys eighth biggest favor of you in history. So when you when you come up with fight like that. I have a lot of momentum behind me. And that's just that's just the way it is a businessman at the end of the day. This is this is a show business. There's the show. And there's the business i'm a prizefighter. I do this for a prize fighting for the buck of it. So you know that. That's what excites me about this sport. Everything about but there's a reason why may whether it was one of the highest paid athletes of all time. And that's that's my goal. That's what i will achieve in the next five years. You see what other boxers make those. Those purses are generally disclosed. And they're fairly accurate m as well. Those aren't as accurate. But based on what you see like where would you put yourself in. Terms of highest paid fighters right now top. Five top five while Could i ask you know this is the first time we've we've had a chance to talk. When when did this dream start for you. Because i don't know if you've seen some of my stuff with dc and others I respect your skills. And i can tell that you're taking this very seriously. I don't think that you are cy. I know you're not fighting top level guys but you're also to like you know no one fights top level guys too so it's clear to me that you're taking this very seriously. It's also clear to me that you have skills like. I think a lot of people have a hard time saying that. I have no problem saying that. I'm just wondering when the dream started for you to be like. Was this something you always wanted to do. Or did someone lead you down. This path of always been a competitive athlete. I was the division one. Ohio state wrestler over hundred wrestling matches was a football player I can run a four point. Four forty second yard dash But i moved to la when i was seventeen acts and become famous and create content. That's what i did. And that's how i built my grand by making content marketing myself acting doing you to doing my business all that stuff and so when i was doing all that wasn't competing and so when these youtubers and everyone started fighting hours the first wave of that and i after my first amateur w you know. We sold one million pages views. The first event sold out manchester arena. Thirty thousand people were there. And i got. I got a knockout in the fifth round and fell in love with sport and i was like. Wow this is fun is exciting. It's everything i love to do. And i just had this burning desire is to keep going and it's only growing growing and growing and when you call it the boxing bug and i feel like i was literally put on this earth to do this at at any point. You see yourself fighting you know. Just the regular guy that you would fight when your ten ino- twelve and thirteen or no not necessarily a celebrity another athlete youtuber. Just at some point you just kinda foresee yourself being on that path to just regular boxers right because you haven't done that yet. I think if the business makes sense a you know. I'm i'm not. I'm not here to have forty five fights in try to do all of that. I'm i'm here to do good business and to have fun and put on massive events you know you see floyd mayweather you know engaging with my brother like those fights i want big fights that are gonna make history break a review records. I'm not. I'm here to do anything small so it makes sense as big names at big pay per views down all right. Listen up as you know. Valentine's day is all need to make sure you're ready for wherever the night may take you our friends at manscaping. The global leaders in men's below the waist grooming are here to tell you that you need to use the best tools for the job so you can be ready for anything on that special day if your girl can't think of what to get you this year then teller to get you the gift. 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That's manscaping dot com slash aerial. Trust me your girl. your partner will thank you. Get twenty percent off and free shipping by going to skip dot com slash area again. That's twenty percents off with free shipping by going to manscaping dot com slash aerial happy. Valentine's day romance. Why do you think your presence in. Boxing bothers people so much. It's amazing to me like even today. Breaking the news tech saigol on jake but why. Why are you reporting on jake. Paul ignored this guy. All this stuff and the the old school boxing media. I feel doesn't wanna cover you. And then the the old school fighters you know there are some obviously tyson. He gave you the rub. It just seems like your presence in boxing while it does seem like you're taking it seriously you're surrounding yourself with respect to people like bj flora's and shane mosley. Prior for some reason bothers people immensely. Why do you think that is. I think i think people don't like change. I don't think they can comprehend how good this is. For the sport. I'm bringing twenty fifty million followers across all my son media platforms. That's like twenty four and under bringing a whole new audience to boxing. That's going to grow this or that On doing here is only positive. And so i think people who don't like change the boomers the the baby boomer generation who is just gonna hate on any kid that wants to become successful. I think there's a lot of jealousy making more money than than these people who have been in the sport for all his time in so of course when there's money and greed and envy like that's going to show through emotion and they're gonna hate at the end of day. These guys are just haters. I'm loud. i'm cocky young. And i'm just doing shit differently. I don't need the promoter. I don't need half the shit that these boxers need on my own marketer on my own promoter amount distribution channel. I sell my own tickets so merchandise. I talked my own shit. Like i'm disrupting the system right now and the people who are haters are going to hate on that and the the people who have open minds wanna see dope should happen. They're going to support him. Where will you train for this fight. You moved from la. You talked about the distractions. There you needed to get away. Will you go back to big bear. Are you going to be somewhere else. We're here. We're here miami training. I wanted to channel muzzles energy. Since he's in florida. I wanted to link up with mazal. Spa these yeah. Yeah i'm i'm linking up with mas role tomorrow of yet. He's going to help me train for this fight. And hopefully i can not been out faster than mazar. All did i know seems seems like a lofty goal. But if i can get under four point nine seconds his record are you surprised that the ufc allowed bent to take this fight. He's under contract with them. They had to give him the ok. Are you surprised they did so. Yeah i am. I am a little bit. I think ben ben loses. It's going to be a battle flex on the afc and and make community in general. And i can only imagine how much they annoy. Fucking hates me so But i do know that. I do know that this could be good for them as well. So you know. I don't know i don't know what what they go. Game plan is or whatever but I am surprised that they let him out of his contract for sure. Obviously recently you targeted connor right. You made that offer for fifty million. You made it personal. You spoke about his fiancee. Why did you go there. Why did you feel the need to go that far over the line. I wanted this him off. I wanted to make a lot of noise. And i wanted to become personal right away. Because i truly believe i can beat conor mcgregor and people don't want to watch a fight where everyone's going in there being like. Hey buddy good luck tomorrow like. That's not the type of fighter i am. We're if we're going to go into a fight. Like i'm going to fucking destroy you and anyone you're affiliated with is a part of the rats and can can be attacked mcgregor's done it mcgregor as attacked could bes wife kabibi religion throne chairs at people like this is the fight business. If people are gonna get offended the fuck over in and bugging choose. Choose different sport. Go go gymnastics or some shit to the best of your knowledge. Was that ever considered that fight mcgregor. Yeah for sure for sure. His manager out he was like said proof of funds or else. This conversation ends right here. Who who the focus kid. Talk shit about connor's wife so we send the pru. I think his tail between his ass and he's like oh. This is not a joke and looking in hindsight Got paid five million guarantee to get knocked out by police. Say you should've take took in the easy fight for fifty million right so he he literally just got knocked out embarrassed in front of the whole entire world the worst fight. He's ever had for five million dollars but he could've fought a youtube kid for for fifty million so i think now they regret it. I don't even know if i'll out considered like. I wanna fight mega but it just not as high as it was before i think he has to go get some wins under his belt and then maybe off consider it you made more than fifty five million though right like that's just what they five dates no five million base. I don't even know if that's true to be honest pay-per-view let's let's say let's say let's say he made thirty million total. I probably made thirty million. That's still twenty million less than fifty million and by the way this is fifty million guaranteed connor. You're still getting the back end on the jake paul as well the jake paul conor mcgregor fights owes two point. Five million. Pay per view buys at seventy five dollars. You know those types of numbers of two hundred million plus gross when you say that. He got embarrassed. I understand where you're coming from. But you do it all see why. Some would viewed as disrespectful to dust. I mean dustin is one of the greatest fighters in the history of the sport. No shame and losing to him. So why would that be embarrassing for connor to lose to him in your opinion. I think it's embarrassing. Because he already knocked him out in the first round it would be like it would be like me fighting nate robinson a couple years from now in nate robinson. Knocking me out. So i'm i'm gonna whereas a real fighter i'm not gonna fucking let that happen and connor. Connor has a lot more to lose than dust. Conner has access to better training. Better coaches better signs better everything than dustin and for him to drop the ball on. Okay maybe if it goes five rounds and it's a battle and it's like a. es by barely loses cool but he got knocked. The fuck out didn't know where he was out of the stadium. I noticed on your instagram You only follow. Two people now thriller and ben's wife why's she she's what she's back okay was like to seize. Ta is thick like she wrote that. So don't know like i thought she battisson. I mean maybe. After i'd be banned you know he. When i spoke to him earlier he's like kizzee's clown is a youtuber. I'm you know. I think there's an angle building here like he'll do this for the fighting community. Do feel like this is paul versus. Mma's is jake paul versus the like how. How is this being built in your mind. Yeah i think it's i think it's j. all versus every single all hater. That's one and then there's j. quality versus the anime world And and then the jake. Paul versus been aspirin You know he. He is seriously underestimating. Me and i'm watching it. Unfold dislike albums they're just like all my opponents to just like everyone does. I like people. Don't people don't get it. People don't get me. They don't understand me. They don't understand my ability. They don't understand the vision i have. They don't understand the roadmap they don't understand how serious i take shit. They don't see what i do when the cameras aren't rolling they just see it as like loud arrogant kid talking shit on his on his instagram. Astle and that's what i want them to see. That's why i'm a marketing genius. Last question For those who may be mocking this right now or who may be saying i. I've seen ben get knocked out already. What am i gonna see here. I don't trust his striking. Or i don't want to support jake paul. You you've seen it all you've heard it all. Why should people by this pay per view on april seventeen. I'm adding ben. Aspirin might knockout meaningful election. You know everyone was posting the shit out of the nate robinson knockout. So you wanna see one of the best produce reduce trailer fight club events dog commentating musical performances Crazy under cards like legendary under cards. And then if you wanna see another viral knockout life and wash it happen me. You're going to want to tune in It will it will be one of the best events of the year. And i think it's going to be really fucking good fight. You know people people are sleeping on being saying. Oh you're boxing wrestler. guess what. He's maxine a disney channel actor so at the end of the day. You know it's more. It's a death match. It's to biased with a lot to prove a lot riding on the line that the whole ma community is is banking are aspirin knockout. Jake paul you have in mind millions of fans wanting to see this knockout. This is gonna be a movie alluded a literal movie. There's so much at stake. And if you're if you don't watch the fight you're you're the one you're the odd person you're gonna have the falmouth so tune in april seventeen. And you're going to get your money's worth all right so that was a lotta fun. Something a little different. There's a lot going on. Like i said in the world of combat sports between what happened on saturday and now this fun look i i know. A lot of people take their combat sports seriously and you should take the actual action seriously but guess what this type of stuff call it. What you want freakshow. Whatever circus type stuff has been happening for a hundred years to suggest by the way the ufc was built on this as well like to suggest that we are all above this sort of thing. A fight between a kid who's to know who by the way is taking this very seriously whether people want to admit it or not and a guy with the resume that i spoke of that been asking has like trust me way. Worse has happened by the way your beloved you have see had. Cnn punk who had no experience zero experience guy. Where like. I mean like i really like seeing pug as a human being but let's be real zero athletic experience of them pro wrestling and they put him onto you. See main cards like to suggest that we are above. This is absolutely absurd okay. This is what combat sports in many respects was built on. And if you don't like it don't don't like it but like this is this is legitimate stuff. I hate to tell you all its agenda and of course jake. Paul is picking been asking because he thinks he can knock him out. He went from a youtuber to a basketball player too now anime fighter who knows where he goes from here and and maybe maybe benkin shocked the world. It's going to be a spectacle. I am hearing of other very familiar names. Who are going to be a part of the card or at least close to signing up to be part of the guard. There's an audience for this. I can tell you that much. There's an audience for this. Jake is taking a page out of the floyd money. Mayweather gimmick with the jewelry in the money and talking a big game. It's an interesting time. And i'm curious to see how it all plays out. So thank you very much to jake. Thank you very much to bend. Good luck to him. And by the way. Shout the amy aspirin. Ben's wife who follow on instagram is playing this up. She's trolling the troll like. She's deeming it back. She's saying that she's real turn. La for his house that he put up market. Amy aspirin well done. I like what you're doing Some unfortunate news no dc. In hawaii on monday. But there will be a hawaii. Show on monday with some interviews and some familiar names. So i'm not leaving you totally hanging but not see. How long will be back the following monday and i do want to let you know that you can continue to rate download subscribe view all those things and more. It's very important. It helps us out a lot. I appreciate it very much and no ufc event. Of course this weekend. They are off but there are some other events going on this one championship. There's lfa there's a big k s w event as well so there's always something to watch if you're an anime fan and i do want to thank everyone who continues to rate subscribe and review the program including my friend gerard brown who writes the most fun. Mma podcast. i absolutely loved the show. He writes. I've been listening to it on youtube and i tunes since they won the hosts are two of the most genuine guys. Speaking about the one sport i love. I finished my master's program and have begun my career in higher education with this podcast really higher education. That's pretty incredible. I hope they continue this for years and years. One of my favorite things to look forward to each and every week keep it up. Thank you gerard. Who also gave his five stars as you know. I'll be here. Each and every kind of i could say the same for daniel cormet taking off next week but i will never let you down the one constant so have no fear all right. I'm out of time it is late. I'm sorry we are late. But i wanted to give this all to you and I appreciate everyone for being patient. And like i said there's a reason for this. Explain it in the in the not too distant future. What i'm saying. Okay all right. i'm out thank you. Tst thank you been aspirin. Thank you jake paul. Thanks to all of you much love back next week. Same time and place to say. I'm out of here.

Boxing jake paul ben aspirin Jake paul jake wrestling dylan Paul youtube ufc nate robinson Conor mcgregor Douglas lima connor Ben aspirin ben Jake paul ben aspirin Paul versus nathan tony ferguson
JRE MMA Show #48 with Henry Cejudo & Eric Albarracin

The Joe Rogan Experience

1:57:14 hr | 3 years ago

JRE MMA Show #48 with Henry Cejudo & Eric Albarracin

"This episode of the podcast is brought to you by on it on it as a total human optimization company. We sell all sorts of shit that helps you get it together. Whether it's strength and conditioning equipment, awesome supplements, and healthy foods and snacks. And one of the things that we have on it. If you go to the website and click on the content section, and you see academy articles the honored academy, which both a physical kademi in Austin, Texas, which is a state of the art strength and conditioning gym with bang, Moi tie and tenth planet, jitsu classes. But it's also the academy link is a section of the site that's free to access that has hundreds of articles on exercise physiology on motivation, different kinds of workouts and articles on nutrition. And it's it's basically it embodies what we're all about it on it. Which is human optimization performing at your best. Whether it's mentally or physically go to it. Dot com. Use the code word Rogan, and you will save ten percent off any and all. Plummets? We are also brought to you by stamps dot com. Stamps dot com. Ladies and gentlemen is a fan. Fucking tastic way you to access all the amazing services of the US post office from the comfort of your own Doma sil- stamps dot com, never closes you can print postage for letters or packages at your convenience twenty four seven and you print the exact amount of postage. Every time you never underpay or overpay again stamps dot com saves time and money, which you can use to do whatever. The fuck you want with you can grow your business. You could just lay around naked. The beautiful thing about stamps dot com. Is if you go to stamps dot com, click on the microphone at the top of the homepage. They will hook you up with a four week trial, plus postage and digital scale. You take that digital scale you way, out your packages. And I mean any package for any class of male any letter, anything and international local, national, whatever you weigh your packages you buy and print official US postage with a regular computer irregular printer put that on the package handed to the mail carrier and your diggity done no need to lease an expensive postage meter. And there are no long term commitments stamps dot com. Even help you decide the best class of male based on your needs. It's fucking awesome. Go to stamps dot com. Click on the microphone at the top of the homepage and type in j r e that stamps dot com and enter J R E. We're also brought to you by my bookie. Ooh, these gentlemen, this way this week this weekend is the big fight Daniel Cormie versus Derek Lewis. Who got who do you think's gonna win? Well, you know, you could bet on it even for I started this podcast people kept asking me things about MMA. You know, always it was always like who thinks going to win. That's the big one. Well, if you think, you know, put some fuck and chatter on it people put some money on it. If you wanna throw down some money on a fight. You gotta check out. My bookie. Mybookie has been in business for years, and the rep is rock solid. You can bet on all the fights not just the main event. And they've got odds on things like which fight will go the distance where the cormier will deliver a first round knockout with a Derek Lewis will win by submission what? Hey, anything anything can happen fighting's crazy business? The only thing you like better than. Watching the fights is getting paid when you're right when you're correct and the fighter you picked wins. Put your money where your mouth is and get in on the action. Check out. My bookie online today. If you join me in time for the big fight on Saturday. My book you will match your deposit dollar for dollar use the promo code Rogan to activate the offer. Visit my bookie online today. That's M Y B O K I E and don't forget to use the promo code Rogan. When creating your account to claim the bonus you play you win. You get. Pay. And we're also brought to you by simply safe, simply safe fantastic home security protection. It's very easy for me to recommend recommend. The fuck is wrong with my face, very easy for me to recommend SimpliSafe to listeners this podcast into friends and people that I know because it's fucking fantastic system. Simplisafe takes care of you with backups in place to protect you if your powers out or if your phone lines down, and they're good people. They're not gonna rip you off. They're good guys who make sure you get a great security system for a fair price with simply safe. There's no contracts, no pricey hidden fees. And I'm not the only one who likes them why or cutter PC MAG and see net all name. Simplisafe their top choice for home security and the best part twenty four seven professional monitoring. From SimpliSafe is only fourteen ninety nine a month. It's fucking beautiful too. Great company. Check them out at SimpliSafe dot com slash Rogan. Go to that specific website, it let them know that we sent you. And you get a great system. That's SimpliSafe dot com slash Rogan to get simply safe today. S I M P L I S A F E dot com slash Rogan. My guest today is a Olympic gold medalist in wrestling and the UFC flyweight champion of the world. He is the great and powerful Henry pseudo. The Joe Rogan experience. Joined by the Joe Rogan podcast by. Boom. And we're live Henry motherfucking Todo world champ. And sir introduce yourself there buddy, captain America. That's captain Eric Alabata seen Henry's coach who what would what do you do with them? Specifically. I've been with him since two thousand four and recently became his coach right before the first the media's Johnson fight in his head coach for an A. And you're in disguising case, some other athletes, try to swipe you, and it's how you happy Halloween everybody happy, I'll read folks. So first of all, man. Congratulations on your victory was feel like. And it's. Feels good it feels try to keep this silly go fist away from your face. Yeah. It feels good because it's kind. It's I I think as a competitor, you you live for these moments. You live you lift these fulfilment, you know. Yeah. I think somebody like, and then I told people just beginning. It wasn't so much, you know, the UFC bell. But it was because it was it. I made it about to meet his, and it was about mattress mean he is widely considered to be the best pound for pound fighter ever. And you're the first guy not only to beat him. But the first guy who not just to beat them. But I mean beat him in like eleven years, but the first guy to win an Olympic gold medal in wrestling and a UFC championship. I mean, those are two Gye canton accomplishments in for sure Thomas like God. It's it's I'd beat the greatest of to me the greatest of all time. And then on top of that. I'd be you know, I can I can make the run for you know, who's the greatest combat athlete of all time. Yeah. Like, I'm going to sport world champion dislike. Yeah. I mean, you're absolutely in the running now. I mean, if he's not the greatest of all time, I think he is. But the argument is that he didn't face people as good as John Jones faced and then fade oars the other fade, Orhan Anderson, silver, or the other people that are in consideration for the grace of all time. I mean, it's it's just a subjective argument. I mean who who knows who's right? But obviously you beat without a doubt one of the best ever. Yeah. Yeah. And like, I would I would tell people there's there's a bit of of admirations that I had for Dimitrius Johnson. Like, I was it was it was like, you know, you're fighting do that. That's that. Almost seems untouchable that you a guy that makes you question yourself. Like, oh, this is this this this guy is that good. What what's crazy is you beat him after he had stopped. You just how long was two years but ca closely about two and a half years ago now. Yeah, about I was like, I think two years four months. That's that's an amazing turnaround between getting stopped in the first round. And then coming back and beating him in the beating him in the championship rounds is really what you pulled it off. Yeah. Yeah. No, absolutely. I I had studied Dimitrius Johnson. Like I've seen as a lawsuit on the first time. What I pretty much did is I got I got rid of a lot of people in my my MA head coach. I just my whole philosophy was I can't be the best. And there's something wrong. You know, emotionally physically everything else just invested when I lost. I'm just like men I need to. I'm looking for a better leader, you know. And and that's kind of what I did. I ended up letting go a lot of my cornerman SR traveling the world went out to Singapore. Went out to to Thailand went out to to the Netherlands, spend, months and months at a time out in Brazil, like I I was on a quest. There was like the of remind masala like Ashkelon from Pokemon. Like, I was just on a venture d I do that. Vision quest was Mathew Modine move. Everyone has to watch that movie. And that's an like, I said it became a session. I knew that if anybody could do it'd be it'd be like, I really did you even after the first time jail when he beat me. I still when they asked me he's like Henry, you know, like, I would I would like guys, I don't know. But I still know that I could beat them even be knocked out like, two minutes and thirty six seconds. Like, I still knew my heart UC one. I sat there press conferences. I know I'm still the one that beat them. What was it about him that made you think that you could beat him? What was it about you specifically in relation to him? And his skill set. It was. I if she asked me what the difference. Yeah. Well, what was it that made you think even after he stopped you in the first round? Oh god. I think it was more. So just believing in my in my abilities. I think me just believe in more. Okay. Henry you need time. Like, I was only doing it may for three years when I fought on the first gel a lot of people don't know that you see fighting for the title, not once but twice the probably been doing for a long time. But when you fought him for the first time is a very that's a very short amount of time to be fighting an MA, it's especially into caliber at Dimitrius. What year? Did you win the Olympics and alway-? Yeah. See down is. I mean when you're doing that you're one hundred percent dedicated to wrestling you have to be right? So will you doing any striking training at all back? Then I did. I did what what happened was once. I won the Olympics. Almost kinda I fell out of love with the sport. I fell out of love with Russ and I remember being nasty Olympics. And being like men, I just I don't know if I have it in me. No more just because you're burnt out. I was yeah. My whole childhood was gone because of the sport. That crazy mask on. What are you doing? I've been waiting for you to say that. We'll do it in stages. So you fell out of love with I fell out of love with business, which is it just because your whole life have been dedicated to wrestling. And you'd finally cheese the greatest of great goals. Yeah. Olympic gold medalists the top of the mountain. Nobody check this out Joe. And it was like in the in the year two thousand seven. That I went through the worst year ever like I was ready to become a world champion, and I went out to the world champions in two thousand seven an identity score point like in the first round like I put out by by Iran, and for somebody's in that whole year when I was just going through freaking struggles like left and right. You talking about just that verse? I couldn't win the tournament to save my life. What wasn't how no I don't know. I truly truly don't know. I think I was I think I probably begin kind of fallen out of love with it. And I remember there's to me there's only two tournaments that everyone to win that was that was the Olympic trials and eventually Olympic Games. And and somehow like because I'm correlating this what the what the firewood the Meech his Johnson. And I remember, you know, just just almost being in tears, like, I just don't know if this is for me and the, but I just stuck with it. I stuck with it ended up putting the Olympic trials ended up going to the Olympic Games and ended up pretty much fallen behind every single match that I was wrestling. So these are kind of the adversity that. I was going through Lenah to become an Olympic champion. You know, it's interesting when you were fighting Dimitrius, the second time Daniel Cormie said something very interesting. He said most guys he goes, I would never give chance you get stopped by DJ. And then a couple of years later, you're fighting him again like he's he's going to have your number. He's going to be better in the rematch. And he goes, but Henry sue who does a different kind of athlete. He and he talked about you competing and then coming back a year later and being he goes he was many times better. He goes the the amount of improvement that he got in just one year was just. Unbelievable. He and I think, you know, I guess you can know that teaching networks I think you can talk a lot about desire to just having the sex only so far. Yeah. But the Olympics has has great genetics a- for sure. But it Tom was it almost becomes a mentality because of philosophies like you almost start doing things almost like to not feel the to not to not feel the pain of losing like that's a motivator to not for the pain of losing Brian. I remember when Dimitrios Johnson hit me in the humane the leg. And literally, I think when you severe was like, I literally sprang a severe low ankle spin those first thirty seconds and the second fight. Yeah. So I fought them each his Johnson like that. But it was it was to me the motiva- was like nine I don't wanna feel that pain of losing a more. I hate it. And I hate feeling second place. I hate feeling kind of kinda somebody's looking over me someone's almost like a manhood challenge. And I hate that. Was it a low leg kick that? That the major your ankle go. What was it? Yeah. It was there's a nerve that you have behind like the bonus per I think it's the peripheral nerve P E R. Yeah. And I got hit there. So it put my foot to sleep just like when Michael Chandler happened to him and bell tower same thing exactly stepping on. And it's just not working and the and the and the reason the reason why everybody kinda got scared because I was hurt. But I remember before the fight. I remember I remember I saw my cornerman like kind of four five. I remember I saw him all I saw him on purpose. And never I remember grabbing my court administrator putting them in Brad in front of me. I remember telling him. Hey guys have been here before like, I was bring thirty first in the world. I'd be I I became a world champion in wrestling like guys, I yeah. I want you guys to have a little faith in need. But I'm gonna ask you guys. One thing. I'm gonna ask you guys. I'm gonna ask you guys to be composed. I said the key to. William this fight is for me to be composed, and then pretty much there's six hours later, they right before you know, walk on this are planned my song. I look back in my corner. And I said an essay guys, I said the key to this fight remember sending be composure so when Demisch Johnson kick ni like, I believe in my own philosophy. I went back to our composure because I was hurt. So he could have stopped me that efforts round. I was forced with south south Paul which had never fight and south pole. You know? So now what kind of I mean dementia? Johnson are playing poker my whole philosophy. And the key to victory was a composure part. And when he hit me, I really did. I was like oh my God. Not again, not again. I'm not gonna last two minutes thirty six seconds, not again. But again, the motivation was not to feel the pain to lose again run. Like, it wasn't desire to win as I just wanna feel that anymore as as somebody that that that that's on a mission do that sacrifices life explained to someone who's never experienced before. What is that pain like, but you train for how many weeks, and then you fi mighty mouse with titled get stopped in the first round. What is up paying? Oh, man. It's I think every fighter has a spirit. I what is the spirit the spirit is your spirit is your dream this bird is that you know, you've watched somebody become a world champion. You wanna be wanna be just like that guy? Your confidence yourself esteem. That's the that's your spirit in its you. Also, we also have a spirit of a war. That's like the the man who sat and what happens when I got stopped with to your Johnson's too. I almost felt like and I've. Ever gone through this not even in wrestling my life like ours. Like my spirit was shot. And I had a kind of picking my pieces kind of start hilly myself like mentally, and I feel like it. And if and if you look at a Joe somebody like Roy Jones junior he got knocked out one time and it became a domino effect because he never he never picked up those pieces. You never started. Healing that spirit. Will he got knocked down again, real bad right afterwards. By Glen Johnson to members to two knockouts in a row Tarver Tarver Kayode him. And then re. And but the thing is there's a lot of factors involved in that loss because I think ROY was also coming off of the John Ruiz fight where gained a lot of weight get up to heavyweight, and then he had a lose that weight get down to light heavyweight again. So he was lean at heavyweight, and then all of a sudden he's dropping down to one hundred seventy five pounds again. And he just looked like shit. He looks smooth. It looks like his body was all sucked in and I just think it was. Bad bad way cut. And you know, I think whatever he took to get himself up to two hundred pounds to it was probably out of his system. And now his body was you know, his hormones probably all fucked up. Just wasn't insane. God, I mean this. Let's be real right? We don't you don't just grow the two hundred pounds without some Mexican supplements. This like, you know, what I'm saying? I mean, it'll take a long fucking time for one hundred sixty eight pound fighter to get up to two hundred pounds. It takes a long time. If you want to really get up to two hundred pounds like an actual two hundred pound body, not just like fill yourself with water and fat, no actually be two hundred pounds away. He was your body's gotta your body's going to say, hey, man, we need a fuck and grow we got resources that need to be allocated towards muscle. We've got a we've got a gain all this weight because we're we're lifting weights all the time. We're doing things you have to do something to get your body that heavy so that all also shut that shit off and see are now we're getting down to one seventy five and you've got to do it in a few months. I think his body was just wrecked. Yeah. Yeah. Marches don't always cut. Wait the right way. Either. Neither do may fighters particularly back in the day this which is really interesting about the approach that you guys took to this camp that you wanted to talk about which is very very scientific approach towards your recovery to train. Methods. So it's everything I mean, you you really had it dialed in as opposed to just trying to wing. It would for many many years was how almost every fighter did it. Yeah. And I think it's a we got a video this part. We got kicked you can see. Okay. That's. That's. I'm. Are. So it was right here the leg like that. That is so crazy just one shin to the still flying. I'm still flopping. Yup. I'm going back to that philosophy composure. Look, I'm still flocking. But it doesn't seem like he understands. What's happened to you? Yeah. You know, you you played poker? So well. Really interesting. Yeah. Look, I'm still a former soon as that happened. I did remember the Michael Chandler fight. And I remember he went on a show and said exactly what happened. So I told. Or other corner. Santino the Franken when we get input ice on his knee. Not his ankle because it was the knee word happened that show. And I remember watching it for that reason to wonder why what happened to him. It's crazy when you watch it because it's just the foot hit the back your knee. Yeah. You know, you could see it again. I mean, it wasn't even the hardest kick in the world. He kinda caught you at the very end with his foot and immediately that nerve just one buoying swamp right there barely. Who also happen to? Scott jorgensen. Did it would fight was that man? You know, what I can't remember? But he didn't win the fight. I can tell you that. Yeah. Anyways. It was a terrible feeling terrible. Terrible philly. Well, you poker face your way through it. But again, Joe like it goes back to philosophy. Like, you got to believe in your you. You gotta be a period there has to be a philosophy period against a guy like the Meech is like there's it's beyond the physical and the technical stuff. Yeah. Like, you gotta be you gotta be just kinda hypnotized up here. But you have to have everything right? You have to have the physical skills. But you also have to have this unstoppable mindset. Yeah. Now, what do what kind of mind training? Do you do do you do any visualization training or do you work with a sports psychologist or? You know, what I like I like reading up on a lot of people stores. I think people's stores are the ones that that. Intrigued me, you know, how you know how Michael Jordan rose to the top. Or at least like that. I think I think that's the stuff that I like. Got a human interest. That's kind of my motivation agreed in biographies, anybody or fees or watching watching stuff on YouTube like, you know, watching giving even watching other sports like I'll watch Michael Johnson's at at times, you know, y watching them when the ninety six Olympics things like that. And watching people celebrations and. Trying to embrace the filling of what they're feeling because it becomes like an addiction like drug like going through these feelings of like the -ccomplish what I what I set out to do. Right. So you like seeing them accomplish these fantastic goals and visualizing yourself experiencing that exact same thing. Yeah. Yeah. As corneas as sounds yet does sound corny. She not coming from the. Once you're the champ all that Cornyn shits out the window at work people serve leaving all of a sudden the ten the fuck out it now they're talking about you possibly fighting T J dillashaw for the bantamweight title. Yeah. Yeah. Talk talk. You know, you just hesitated. Negotiations. There's. Not just talk. He wants to we want. Yeah. No. I'm sure where's that right now? Because there's a there's going to be a card in January out here. And there's just announced. Oh, wouldn't it? What what was that is the same night as the fate or Ryan Bater fight which pisses me off. So I wanted to go see that fight January twenty six. Yeah. That fights going to be at Barham and the UFC fight. I think is at the stable centre or maybe Anaheim, Anaheim Anaheim Anaheim in the pond. Oh, okay. Here both here in California. Well, just twenty million mother fuckers in California, plenty of people go around yet audience. Yeah. We we've I think there's been talks, but it's been now, you know, we I don't think I'll e my manager has really truly like actually sat down and talk with the US. And I think I think everybody wants to do it though. Well, it's one of two things is going to happen there. Right. It's either. I mean now the DJ is gone to one. Dimitrius Johnson just left the and went over to one FC in a one FC for people who have no idea what we're talking about is a gigantic organization in Asia. They are literally the equivalent to the UFC and Asia, and although many people in America are not aware of them. They don't know who they are. They're a huge organization oversees absolutely gigantic and they do a fantastic job. They have real high level fighters. Ben aspirin was there champion he was undefeated over there. And he had I think at least one five maybe two fights left in his contract. I forget how many and they made a deal and the deal was they take mighty mouse. And we get Ben aspirin. And so that's where it's out right now. I love the deal a love it. I love the idea of it. I mean, I feel like mighty mouse. You know, he he loves the idea of starting new a new organization, and you know, they're gonna hey that motherfucker. Nice. Yeah. Why we get paid exactly? And he also likes the mentality that that organization is operated with which is respect for the martial arts. They're not into this. You know, what we saw with the Conor McGregor? Could could be number medoff fight all the trash talking. And all the all the stuff that you're seeing that was becoming more and more prevalent in the UFC, you you don't see that at all at one of c. And that's something that mighty mouse. Very happy. Yeah. I think I I think congratulations to banana. I think he's. Everybody's in trouble. Yeah. The fuckers are in trouble Penasco view. You'll like why can't I get up the nationals one of those guys that he's very he's a very confident. He's a very dangerous human mean because he knows that he's going to be very confident. And I'm I've always told people that says, hey, maybe the best in the world is on the UFC, man. There's some due buddy, Ben aspirin we saying his praise for here. That will take people think could be controls. Good of top you wait till you get a, you know, four time. Finalist time and see chap on top you that? That has an aide Olympia and his teammate yet. And and Olympia, I mean the duties the dude is he's a bad Metcha for anybody. Joe anybody know Ben asking I mean, there's a reason why he's undefeated. He hasn't been hit in several fights who is detailing woman. The last time he got hit. I had him on the podcast. 'cause I I wanted to let people know about him. I mean, I've been a big fan of fan of ban aspirins from back when he was about toward champion. And if you watch his fights belt or against Khorishkov and and Lima Lima beast man, and he just dominated them just Lima fucks people up man Lima's, a dangerous dangerous cat and Ben ask cringes loop. Oh, you're on your back. Again, look at that can't get up, and you take him punches, you know, and he's it's just a different Cowper of wrestling. And I've said it many many times, and I I'm sure you believe it as well. It's the most important skill for 'em as wrestling, it's it dictates where the fight takes place. If you wanna stand up, you the guy can't take you down chocolate del style. And if you want to go to the ground, you're the one gets to dictate where the fight takes place, that's too. If you're the superior wrestler mean is the the best base for a really believe in especially a guy like banks. I think Ben knows that his. His striking. Not that. Good. Right. So he just relies on this is this is what I know. I do a better anybody, and I'm going to control this. And you're gonna know how to do it, you know? So that's what that's what makes screen dangerous. He's so dangerous. I mean, a real bad fight for him would be someone that can figure out how to keep it standing like Jay hair on gave him a real tough fight in Bella Tor because Jay Huron is good wrestler and kept the fight standing school. We forget what what his take on that fight. Was we talked about it on the podcast? But I don't think he was too happy with his training for that fight. But, you know, someone like Tyron Woodley who's also very good wrestler, whose very dangerous striker would be a tough match up for him. But they're really close, friends and training partners. Yeah. Well, this is another thing too on the flip side is like Tarrin's been wrestling since for years. I think so he knows what the Ben asking. Experience is scary. Yeah. I mean, people would be lucky to you. Kind of take them down. If you want to give it a no-take. He wouldn't he just wouldn't let people dig him down. Yeah. Pedestals talking about it. You know, saying listen, it was back when pedestals a champ. He said if I was forced to fight Ben aspirin. He goes, it would be a fucking terrible fight for me. Just take me down beat the shit out of me. He's like that's what he does. Then was to win a belt the two thousand eight Olympic team would have five belts, and we gets to DC has to and and Ben asking we'd have one that's five UFC belt of if he came into the belt his teammates. Well, they are going to open up eventually that one hundred and sixty five pound division, which is what Ben is shooting for Ben would like that division, you know. And if he said that if he had won sixty five and tyrant kept the welterweight title. That'd be great for him. I just don't see the UFC doing a five pound weight difference. When all the other way differences are so huge. I feel like the smart move would be ten pounds every every spot thirty five forty five fifty five sixty five seventy five like move seventy two seventy five like when the USC had a light heavyweight division initially that the division was two hundred pound division when Tito Ortiz first one, and I believe it was two hundred pound division. And then they raise it up to two. Oh five. And I think just they needed a one ninety five to I really believe and probably to twenty five, you know. I think that would that would round it all out, which probably will all happen eventually. Yeah. Yeah. That's interesting to see how that how that on foes. But as of now, it's an aspirin. She's going to be fighting for the belt pretty soon. Well, he's calling out Darren till he wants to fight Darren. I love a love that is a classic striker versus grappler matchup, especially after tire just smashed them. I mean tyrant end the hype train for until we we learned a lot about Darren Darren is a sensational striker very very dangerous striker, but keeps his hands. Low keeps his chin up high, and you know, tyrant has proved himself to be really dangerous even against elite. Strikers, you know, you look at the wonderboy fights. I've said this time and time again, you look at those two fights wonder boys known as being one of the best strikers to ever compete in the UFC. He's got a I think it was fifty seven, oh as a kickboxer something fucking spectacular amazing striking skills. But yet Tarin hurt him in both fights both fights Tyronn was the one who landed big shots and had wonderboy badly hurt. And then you look the same thing with Darrin till Darren tells known as being this unbelievable striker Tyronn clips him drops him and then strangles him. So you know, it all changes with these guys. These guys can be the best even the best wrestlers like sometimes it isn't translate to the sport. Like it takes a special. Somebody to adapt to the sport. Not just the wrestler. Yup. And I think Tirona has has adapted to his time to his right hand. Men if you're able to take out two strikers like that you're the real deal who's on questionably the real deal. I'm fascinating to see whether or not normal medoff and then aspirin go at it. That to me. I had a fight that. I really what are you saying Floyd Mayweather with stopping the nonsense. I this is what we were talking about is not going to happen. He has the same agent. Listen gonna happen. Value happen. But this could be as much more of a grappler than as or than he is a striker. I mean Connors striker that that sort of made sense if you wanna talk about levels, I think Ben's, I I think Ben's party the better the better, grappler, Luna. Fuck knows. That's what I wanna see. No, I wanna see that. But there's there's levels like even though like, they don't give black belts. Interesting. There's there's there's levels. There's and I think binational was one of the greatest folks riders of all time. Like that's how dangerous he is. He's putting the best the best kids in the world, pretzels and submissions. They just wanna get out of his. Yeah, he's he's like a bull constrict. He's he's stunning in his ability to control guys like you like what the fuck man like Khorishkov. I mean and Lima are two great examples because you look at those guys in Bela Tor, and they just smash people to Korsakov has one of the craziest spinning back kick knockouts of ever seen in my life. He sent this dude flying through the air. See that couple of fights ago. The grand prix. Yeah. See? Fucking nasty. He hits the due spinning back kicking literally leg launches them into space. And then smashes him when he goes down to the ground. I mean, you look at what Lima's been able to do to people when the ROY McDonald's was very close fight at this wash. This. We'll be this boom. I mean, hey lost that too. Then boise. I don't know where that was. But so course, cough. You know, if you watched the chorus cough fight with with Ben aspirin, and it's a mauling. It's it's it's just a guy just getting fucked up. That's what the fight is. Ben ash, cringes dominated him like absolutely dominated him. So do try to jump back and landed it landed right as he was in the air out. She wa wa yeah. And knowing bent in this in this got never got a punch off of Banat. It was it was total domination same as the Lima fight Lima crushes people men Lima's one of the scariest strikers, I mean, he knocked out Korsakov. I mean Lima smashes people, but we see Lima against Ben aspirin. I mean, obviously was a younger Lima. I mean, he's got more experienced now. But the difference was so stunning. What do you? What is this? No, it's not no. Knows a to Chinese guys. This is not asking you got to trust. This is not aspirin leam either. I'm sure the. Joe being a bully. Trust me. Those dudes are not the same guy. Joe? You lose your patience is there. It is. Man. I mean, just the way he manhandled them like his wrestling is just you see guys that are used to defending take than they find themselves on their back and you say holy shit. Man. I think he did get up kicked here. His nose got broke. He got cracked. I mean, he Lima's a fucking monster. Man. He's a super dangerous striker, and he's huge for the way class you stand next to lean you like Jesus, how do you make one seventy? He's he doesn't end in jacuzzi at the hotel. I've seen him. Yeah. No. He's struggling to make that weight. He's a big guy. But anyway point being Ben asking at one seventy super super interesting fight. I would like to the personally the fight that I would like to see I'd like to see him and him and Coby Coby Covington. Ben and Kobe that would be really interesting. Yeah. I think but isn't Coby next in line for the title. I mean, I think he's got the interim belt. If he has the interim belt surpri-, I'm surprised still how. Yeah. Maybe is in the White House. He doesn't have it anymore and sit in the White House. But I mean did they didn't strip him. Did they because there was some talk of stripping him because he was supposed to not that. I know of I don't think there was ever a strip. So I think they're I think they're trying to market. I think as soon as you you get the champ, computer. Here says he was the interim from June ninth to September eight. Oh, so they distributed awfully so the tripping was because they wanted him to find them the Darren kill card when Darren till fought tire. And they wanted him to fight tyrant. And apparently he had gone through. You know, hard training camp off busted up he needed time to recover. So I guess they stripped him the hell's man interim titles. Interim titles are like attached with velcro just disappear. They get yanked off you. They're not they're not really they're not really like especially at UC to twenty nine. They all had bouts of Tony Ferguson had CONNER how you know. Obviously could be had his bells you had three people off at around bells, the Tony Ferguson one to me is is a shame is shame that a guy gets injured. And then they strip them like that that doesn't make any sense to me. I didn't like that one. That one bothered me. I feel like Tony should still have the interim title. I really do it without like the third time. Then find have had fine. No sucks. But the other one wasn't his fault. The other one was Khabib could be right. Could be supposed to make the way, and you know, who to to one medically. Could be pulled out and how many times Tony pullout? So he pulled out once for sure because he was injured the last one is neat blew apart. And in Khabib definitely got yanked off the card with the weight, the weight cut member way coat was so bad that his kidneys were failing. Either way we've been there that that's the fight. Now. Do you do you like fighting it thirty five 'cause I know you fought a thirty five for a while when you struggling to make flyweight you had you had some issues early on in your career where you really didn't make the weight. Very well. Yeah. Was god. I was. I was getting older. I think in my career. I think the reason why started having weighed problem was because of I was just getting older now doing some crazy stuff. Like I used to cut like like I used to I used to. I used to to cut about sixteen pounds like in two two hour sessions. What? Yeah. As a as a flyway or supposedly flyway, why are we doing that? Because I felt like because I'm a wrestler think my my whole philosophy at first when I when I got into may was kind of like, I an rested. We would never get the same recovery. I know it stupidest stupidest heck, but we would we would we would never get the recovery that a fighter gets. So to to me was like, dude, I can I can stretch this as as long as I can and I can suffer the day of wins. But I'm gonna recover within twenty four twenty twenty eight hours. Sometimes, you know, so to me, I I was looking at it just that an odd way. So catching up to me. So you just had confidence in your body's ability to bounce back. Even though you're putting it through an extraordinary amount of stress in losing massive amounts of weight. Really quickly felt like your body can handle it. You're tough. You're used to it. Yeah. It was it was the whole 'cause you know in wrestling would make wait like every every every week. Sometimes Russell so much that we're we're used to kind of like that whole the whole struggle side of things. And then okay Russell game. We'll do it again what kind of way cut. We're talking about. When you were wrestling how much we cutting and that was a lot more disciplined than, but I was probably doing about twelve pounds. But I had no fat like at that. At that time. I was eating just as healthy and as clean as possible because I I would make weight every every every every three weeks out of turn, you know, had George Lockhart on and he was explaining to me that a lot of people think that when you cut wait, the, you know, like you're cutting out fat. He's like, you're not cutting out fat. You're cutting out water, and it actually helps to to have more muscle because muscles mostly water. So you you're just draining out your muscles than replenishing them. You know, when he was explaining that to me, I was like I never really thought about that way. Like a guy like a Yoel Romero who's very much. Skier can actually cut more way. Yeah. Yeah. Now, you're pretty muscular guy for a flyweight. So you were walking around how many pounds over my nose? I was probably cutting for like maybe twenty twenty five. Wow. So you're walking around like one fifty and get down to twenty five. Yeah. Holy shit. I just I just had lost. I just you know, a lot of the to you because you fight three times a year. Like, you're not always not always honest with your diet either, you know, comfortable coming from Mexican December. We like to love to go to my mom's house, and it's gonna be lay down. But when you're in camp, how do you organize your nutrition? Oh, I'm disciplined a have have a mill company they deliver my food like every three like every three days, and is your meal prep based on your suggestions to them or your recommendations and directions to them the end. No a lot of space on kind of. Well, my diets just according to kind of like my training schedule. So my my trainees very very organized. Like now, Joe I'm like a pretty much I'm on among on. I'm a professional now. I guess you could say like, I do things, you know, the right way use the whole scientific rather nutrition relgious almost like how Bernard Hopkins kind of as he got older money kind of change his whole philosophy start using science more. I think everything now in my life when I get ready for fighters all based on a saw based on science. How did Bernard changes training? You know, he's he just started recovering more. I think he started using a lot of those neural stems. Hyperbaric chambers stink things that Matt things are that matter and just more scientific base. Just this whole training all like all around and did you incorporate any of those methods? I did I did actually I ended up connecting with this connecting with this company called neural four swan science space company, and I actually wanted to bring them into kind of to kind of talk about it you'll because this right here might just change my my whole philosophy. We're talking about the whole waco's how the whole way way because how I struggled to to how my whole chain has changed because of because of because of science a science, that's very that a science, that's very I guess complex. You could say you gotta have the right people man like dictating your schedule. So when you set up a training camp like this how far in advance. Do you sit down and work out? All the details. It's almost like the the morning that we wake up as what we know. We're going to do. But how like say if you know, you have a fight in July. When would you start preparing for that? And Wendy, sit down and map everything out. Well, we try to map things maybe about three months in advance kind of like a preparation to leading to the camp. And that's kind of like the phase at we're on now. Like now, we're on you know, if I if it is an fight in January, it's almost like our schedule. It's like there's there's there's a pre-test to the big test. So tomorrow's November first. So if you were getting ready for a fight in January you would start ramping up somewhere around now. Yeah. But it would it would it would be more of. Yeah. It would. I think the first the first monthly nut to the next eight weeks would be a lot of it would be a technical and tactical which is working on those particular areas that were that we believe we're going to be in. So you're not doing anything crazy strengthening conditioning wise, you know, trying to break your body down. No, no, because it's all taller learning phase at that point, you know, work in the body gate, preparing the bottle with a lot of body motion movements and things of that matter kinda just bring more circulation to certain parts of my body. Than rather than, you know, somebody picking up a kettle bell and throwing it and and crazy things like that. Like like, it's all it's all sports specific Bryant, right? Ranger emotion. So how do you organize this like what who what is the team of people that use in like who's responsible for what? Yeah. Well, like, I said, I think the whole crew in the back the men the men Americans with you get the rest of the avengers or I'll wait in the waiting room the for. Let's say we I found him when he heard his hand, and he had the rehab it. So. So I'll see going into layers is going. He had hurt his hand before. He is I fight with Sergio Pettis, and I was trying to find any way for him to still compete, and we found somebody using this machine which led us to actually neuro force one in Kareem and all these guys, and we tried to force it for him to get back in time. And we have video of him just screaming in pain trying to get there. And we thought we stayed off for a couple of weeks. And then the the day of the face off. He went to cut weight, and he said his risk hip slipping out, and we had to pull them from the five you want to see the doctor doctor said no way shouldn't fight. So what was the injury? Pick. It was a an ended up being something with brains ligament. He I think was a ads sprain. Like one of my ligaments in my hand. So there's just there's nothing I could do. I would I would I would open the cat bottle for the for you know, to kind of to brush my teeth, and it when it hurt to that point just like man, I can't do anything. So then I you know, I ended up they ended up Eric here ended up connecting me with with neural force and found out that they had like these certain machines that help you heal faster. What are the machines do accelerated recovery? So it was like neuro stem, and they have about a thousand programs on it. And it just forced him to to recover a lot faster. The the best example was you've see fighter Pantoja he was on Altima fighter twenty four with us. Our number one seed that we picked Alexander Pantoja. I saw him blow three ligaments out of his elbow. And he started crying because he had a fight in eight weeks in iron. No Scotland and. I said, no don't go home tomorrow. He's supposed to be going back home to Brazil. And I said none. Let's try this. You gotta try and they did it twice two sessions day for ten days. And he went back, and he any fought he fought that gain beat him naked choke in that guy. Neil Siri wanted to gun retirement. So after that, I was like would we need these guys Henry, whatever these guys, depend Toshiba, whatever we need to do for you. So when a guy when a guy gets injured like that, and you you're still going through camp. How do you work around that injury? Just say, okay news, nothing squeezing nothing where you putting any strain in those tendons, nothing where you doing anything with that hand that's gonna reinjured it. I think he just have to hope for somebody or rapid very well like you're screwed. Having like a hand injury is like the probably the worst injury. You could have. I mean, we eat with these hands. You know, right. This is our this how we survive, and when you have an injury like that there's going to be fighting with the other. Do you? Remember when you ri- favor fought, Mike, Brown and broke both hands. Yeah. Just started throwing elbows and slapping just didn't give in for a second. So tough that motherfucker is two broken hands trying to find a way to win. It's miserable. That's a. Yeah. It was a title fight to. Yup. Yup. Do main rematch title. Yeah. No. But I I want I wanted to bring in Joe if you allow me I'm could because I'm honored men. And I think I think I brought the men jokes. I wanted to kinda share kind of like the new age stuff like something that's just taken over the top. So Kevin if you can hear me come on Kim is a bit long delay. There's like a thirty second. You can go grab them. Okay. On Graham, go grabbing captain he's doing come back with a new layer. Come back with a Cape. He's in a comeback naked. We don't have another microphone though, unfortunately. So he's going to have to take your spot. There's not none other microphone. He captain America will use a fourth microphone. We actually have to set it up and it's not up right now. So what do you think of captain America is Larry? We got to them. You know, how you are with a. With Eddie, this kind of ho how high with them, you know, it says no that certain relationship. Hey, man that helps how are welcome. How you doing? Joe shop tell everybody who you are. I mean, I'm Kevin longoria. I and the chief science officer for neuro force wanted to go. And then I'm a neurophysiologist as well. So keep this about like a fist from your face. Okay. So tell us what your role was in camp. And what what you did to help them? Get ready go. Yes. So Nero force one is a neuroscience based training company and a medical great diagnostic testing company as well where you guys where to Scottsdale, Arizona. So what we really focus on which a lot of companies aren't talking about is the role of the gut in the mind in conjunction with your physical training. So essentially what we do is we start off with a really comprehensive baseline assessment wanna run up through everything. So the traditional functional threshold powers automatic nervous system. DC brain potentials. You're really what you wanna do. You wanna put somebody on a on a normal curve? What is DC brain potential DC brain potentials, you want to be like Daniel Cormie? Yes. DC bring a little bit like DC. Basically, it's an objective measurement of your central nervous system. So you can actually your central nervous system as basically the data aggregate. Or if you will. So does take information from your metabolic systems, your ought to Phnom ex kind of coordinate things like neuro muscular and metabolic officiency. That's kind of the data center. If you will. So this is a measurement of potential basically how much energy you have in the in the central nervous system to go coordinate neuromuscular and metabolic efficiencies, which is really what we focus on. So so as this on like a chart or you getting like is there a number reading that? You're getting like what is it that correct? Specifically for DC it's going to be available, and then you compare that to normative ranges. But most importantly, what it is is trending data over time. This is an assessment that we would do on Henry every single morning. It's a home test kit. We really believe in just collecting as much data as possible and trending data that when you see it changed essentially get predictability in terms of today's a no-go day because central nervous system is diminished. We're just going to be going through the motions, we're not gonna make physiological ad- applications. And your inflammation is really high. No go because we're not gonna go risk injury. When we can't make up patients. So this is a measurement. We would do every single morning where we can look at autonomic nervous system, which is basically things like recovery sympathetic para sympathetic, balance, DC, brain potentials and metabolic systems. And what is what is measuring all these things? Is there a device devices? It a yeah. Yeah. This is a pretty amazing device. We actually got it from the UFC performance institute. Shut out to those guys Clint bow and Roman over there. Set us up with the technology to basically a chess strap that does heart rate variability, so time and frequency domain analysis, and it does DC brain potential. So they'll stick your right here on your forehead, basically four minutes, you just kinda relaxing. We collect pretty amazing data and it breaks down into four different categories. What's called windows of train ability. So says today, we should focus on strengthened power or skill acquisition based on metabolic readiness. Oughta Nommik readiness in DC, brain potentials. So what is our body prime to go do today because if you're not primed your nervous system doesn't have the energy? It's going to be going through the motions. So you're sort of their to dictate when it's going to be a hard day when it's going to be an easy day. Correct. Yeah. And that's something as you. I'm sure you guys know in wrestling. It's always hard. Always let's go. So this was a little bit of an issue in the camp at the very beginning. If you could imagine Henry wakes up, it's a sparring day where maybe even supposed to do. Today's he wakes up feeling really good in nervous system is out of whack like sorry, man. I know you feel good. But you're not you know, why? So we would go Nogo that day. And you know, as you could see it all worked out in the long run worked out fantastic. But was a weird for you to feel good. And then we told you gotta chill out. Yeah. Yeah. It was it almost takes a while to kinda dappling. I started as started recognizing like my body change in how I felt and spine and how kind of I just thought recovered also God, this is this is crazy like I didn't run out all this whole Cup. So do you get a baseline off of this era? You gotta stop moving around you freak me out. It's doing hand signals back to translating for the deaf people. So do you do a baseline on this before you get started? And then you as before camp get started. And then when camp starts ramping up then you start measuring all the various details. Correct. Yeah. So we do a comprehensive baseline assessment, including the omega wave as well. You know, six or eight hours of other testing, everything that you could think of under the sun, we put together a basically, call of this is what your sub optimal at this is what your average at this is what you really damn good at. So basically what we wanna do is explore your functional strengths. It's what you're good at. But then we also want to focus on your functional deficiencies in a sport like MMA. We also sometimes how the advantage of looking at your opponent and making certain assumptions in terms of their weaknesses their strength going against somebody like DJ. You don't you don't really have that advantage. So we really needed to focus on his what Henry is really good at his ground game. You look, you know, we're doing nervous system assessments while he's on the ground. His sparring partners are stresses since are going like crazy. He's common down because this guy likes to be on the. Lower rolling around. So we pinpoint these little strategic strengths and deficiencies, and then we target all of his nutrition supplementation. A big thing that we focus on his nutrient timing something that's not really talked about as well when you're talking about gut health, and you know, recovery managing the hormones associated with exercise. You gotta be getting in the right nutrients in your your energy anabolic and growth phases. So for nutrient timing you talking about like when you're actually eating and what you're eating. So you're planning that out as well. One hundred percent. Yes. So we put together a nutrition program and because training varies every morning. We're deciding what we're going to do for the day. It's completely dynamic. So we're kind of reinventing the game period ization in programming because you can't give somebody in eight week plan. You have to check every single day. This is how you stay very dynamic, and you avoid plateaus and just the issues, you know, it's always gonna lead to sub optimal performance if you're programming out. So every day we adjust we're doing this intensity of training. We did a video to MAC segment. So we know exactly how much like junior burning at various levels of. Intensity. We do heart rate tracking during your training. This is exactly what you have to replace following. So I'm standing on the sidelines after every practice mixing up custom supplements for him as well. So this is something what kind of stuff we have our own supplement line right now, frankly, not because the world needed another supplement line. It's not really what our goal was in sports. Like this. You have to be so careful what you're putting these guys body. So we just went the route of going GM certified water you sought approved on everything we do eventually we wanna try and work with the bad company because we're not we don't want to be in the supplement game for us. It was just quality control. So being nervous system based company. Obviously, we're doing things like will make a three D H as BCA's to maintain put on a little bit of muscle. We do a lot of big on. I believe in. This is the generation you can the superstar very good without a big big insulin response, but very good replenishing glycogen stores following to minimize cortisol and inflammatory responses and things like that. So every day it's a little bit different. But yeah. We ended up going with our own line. And one of the biggest things that we never really talked about in the fight as well as the role that gut health place. So that's something Henry does year round, regardless of when we're fighting is take our line, which is called freedom. Cleanser store this world. Renown utilized by university. Researchers all around the world right now. And basically it's all just about restoring good, gut bacteria prebiotics, probiotics and lymphatic cleansing. And this is going to be something that really played a big role in his weight cut as well. It's kind of a missing link that athletes aren't talking about. But good gut health is going to helpless serotonin productions the recovery relaxation mood production of brain derived neurotrophic factor. So our nervous system can make these adaptations and learn new skills and things along these lines. So this is something in my opinion. A big reason why you know, he had the issue with DJ the first time around Henry Henry, we'll tell the story like he had gut inflammation, so bad that people would say, good luck before the fight tap is gut. And and that hurt him. Yeah. That's not normal that all goes back to the issues assoc-. With weight cutting as we were talking about a little man but getting that gut health, right? No, inflammation. And that goes a long way. Now, how long have you guys been business for we've only been in business for about eight months where we're still very new been working with Henry a little bit longer than that? But yeah, this company's just getting off the ground. We kinda rebranded a few months ago just opened our first acidity as well out in Scots. What is your background in? I'm a physiologist. I opened the first mobile medical grade diagnostic testing company in Arizona. So basically, I have these diagnostics and largely with China trying to fix the healthcare system a little bit. You know, we want individualized solutions. We want data driven outcomes. Right. You want quantifiable progress? People wanna feel good about what they're doing. But maybe a doctor can't afford this big ass metabolic cart. Or they don't know how to use it. So what I did is. I purchase equipment hire technicians. And we would bring it mobile now technology is getting smaller more mobile. So this was my idea of how I would go make my little debt and the healthcare system. You know, there were issues with scale ability. In terms of finding good technicians. But the goal is just to go out there and provide data driven solutions. Right. We live in a world of of subjectivity guesswork, a very punishment oriented fitness system, where it sucks the start working out. You you typically gain weight if you're doing the right stuff because you're getting hydrated you go get injured. The goal is to redefine how we assess people. So that we can find little little tweaks for positive reinforcement. And that's it goes a long way with Healthcare's wells, fitness. So you guys mostly working with civilians or are you working with pro athletes or right now, we're in the research and development phase? So we're really only working with guys like a Henry, Victoria, Anthea, a very bad ass wrestler. We're working with right now as well. Just some amazing people largely for research and development. We we trade them the training for the data know you guys get together we've been working with Henry about a year. He I he knew our CEO Karima mean a great guy. We've kind of all circle around Kareem. He brought us all together. But you know, he came in probably about eight months ago for a little bit. But. For the first camp, and we met talked. And now Henry we're straight up. He's like man, you know, your stuff, but you don't know Emma, may so I took that personally we spent a lot of time together I had to learn the sport physiologist, not an eighth is eulogised. So we really took the time to get to know each other. You know, hang out a lot. Now, I got to go to his house and wake him up every day for eight weeks. So that was gonna know each other pretty well do as meal trips and so much. Yeah. That's a fantastic combination. Though, a guy like you who knows so much about the body and recovery and a real super high level Olympic gold medalist athlete. I mean when you get that combination. That is that's really a dream for guy. Like you end for a guy like you like for both of you guys to come together. Like this. I understand why you wanted to bring him on as well. Yeah. I mean, you know, you understand half. If you understand half. I don't pretend the DC mind thing. Yeah. Yeah. That's that's important. I mean, I I do feel a hundred plus able to work with somebody like Henry, he's the hardest working guy out there. And and of course, the hard work goes a long ways. But man, this guy's genetic freak as well. I found the ability to test Olympic athletes, many other sports as well. This guy makes that outpatients faster than anybody. He came off a twelve weeks. Eight sixteen weeks maybe have not training veto twos. Already in the high sixties functional threshold powers that would go compete with the world class ironman that I'm training and things as well. And then I mean, we we did some amazing stuff. If you looked at the body composition changes that we did in seven weeks. It wasn't even a full eight week camp. He put on four point two pounds of skeletal muscle mass like good mass, which as physiologist I would call bullshit on. If I didn't see with my own two is those pretty credible and credible in Henry will tell you he may be picked up weights like three or four times, we don't really do traditional strength training because you know, a lot of people just it's called vector based training. So a lot of people do things like squats and deadliest. This is an Axial plane. We don't live in this up and down plane. So we break it down by vector. What angles does he need to exert an absorb force in very effectively and very rarely does that come down to actually utilizing awaits. We do things like positional isometrics and e censure training and things along these lines number one they integrate with the nervous system, very effective metrics. Yeah. Isometric what kind of like planks of? I mean, that's that's kind of a low level of it. Yeah. Largely what you would want to do is like a biomechanical assessment and look at overactive and underactive muscles, and you put them in very specific positions and you'll ever Joe it's called for reciprocal inhibition. So basically in the most basic turn went on flexing. My by set, my tricep is relaxing. So you hold certain positions. So that you want to turn on certain muscles and kind of turn off other ones. It's kind of a high level of stretching proprio receptive neuromuscular facilitation. So this is what would be done in like a PT office. So in for wrestling like what kind of exercises? Would you do that would incorporate those methods? I mean wrestling is largely torsion sports. So when it comes to wrestling, we do things like like Kaiser like pneumatic compressions and things like that. So instead of using weights we use air pressure, basically, it's very smooth very low risk of injury. And they live in this this torsion planes. You a lot of transverse plane, and we do a lot of velocity base training as well. Actually, really interesting study that was published recently they had a lot of guys working out for a full year. Some only did velocity never actually picked up a weight the other ones that traditional strength training, the people who did velocity base training now. No, actual training got stronger with less muscular hypertrophy. I mean, they didn't get as big, but they were stronger at the end of the day. So when you look at something like wrestling, and may where you gotta make a low weight, but you're gonna to be strong as possible, you know, velocity bay straining is kind of the way the future. So this is kind of our general Jim concept that we're building right now is the gym of the future may not need weights. We're going to be next door to these cross fit gyms where they're throwing all these weights over their head getting injured or next door empty, Jim and people are getting stronger. That's that's kind of the gym of the future the way, we see it. How would you define velocity based training? So basically what you want to do is. It's kind of like the new one rep max, we all know one at Max's aren't the safest thing to perform, right? So you would there's different assessments actually, what I'm wearing here on my wrist right now, this is where it will tech the future. This is something we're testing right now, this does velocity. So I could stand in any position. I could do a push press record a punch. This is going to measure, my velocity. You're max velocity at no, wait would be your one rep. Max velocity, basically. And then you're going in you're doing your training. So max velocity every single rep. When you hit twenty percent dampening so CEOs at ten meters per second soon as I hit eight meter eight meters per second, I stop so this is kind of what they call fatigue. So you stop that. So instead of doing, you know, you're going to do eight reps you do as many reps as you can't until you reach a certain dampening of law city, and what are you doing them with largely things like the Kaiser the functional trainer if you're familiar blasting band work. Yeah. Things like that. I mean, very rarely will throw like Indian clubs. And things like that in there as well. So it all depends on the sport. And what we're focusing on that day, you know, metabolic readiness things along those lines. But it's all just about training in the right vectors and being able to not only put out force but absorb forces, well, which nobody really talks about if you look at largely other professional sports all these injuries are happening, and they decelerating phase. So when people are trying to slow down, this is absorbing force. This is kind of similar through some of the pieces that aren't trained in anime as well got to be able to absorb four. She's like you put it out. Now, when you this risk thing that you're wearing it measures velocity. So how is it doing? So basically, I have one here, and then I have one on my shoe as well. So it can do it by using two centers it can measure relative low thirties. So it's reading one relative to the other. This is also doing everything that a bad s traditional wearable would do as well. So it's doing my heart rate heart rate variability, which is actually clinical grade, everything we do is got to be clinical great because what's the point of collecting data? It's shit. Right. And then it does pulse ox summitry. So I'm looking at my oxen. Saturation of the next version is going to be able to do hydration all kinds of bad stuff. What's really cool about it as well as it can measure form any exercise that you're doing we can compare you essentially to an ideal form, and because we have to you don't even have to tell it, you're doing a power clean. It can read your motions and things like that. And it gives you like a consistency number as well. So we one thing we really talk about is not building muscle on top dysfunction. We have to get your bio mechanical patterns, right first. And then we start putting muscle on. If you just put most on top of dysfunction, you're facilitating further dysfunction, would you have to wear one of those on each hand? I mean, I'd say the ideally for someone like a fighter you, obviously thrown with both hands. I think it would be ideal. It's really difficult at time sync multiple devices to be on the same timeline. So that's something. We're working with this company amazing company actually out of here. L A to develop this thing right now. So that I would say that'd be the goal. It's not something that's going to be applicable to the average guy though as well this. We're we're trying to bring this type of training to everybody. Would it be possible instead of time sinking? It you have a left and a right computer, like two different computers at are reading data both on one off the left one off the right? So you don't have to coordinate them. You just look at the the various data. Yeah. I mean at the end of the day, you still would have to sink them. You know? So the thing there you'd be collecting it in two different sets of hardware, you'd wanna API connective. He put it up in the cloud. And then you still at the end of the day have to find the same time axis. So it sounds simpler than it really would be. That's why this is the only wearable in the world right now that has even one in the foot. And so this also allows you to track your gate while you're running and things as well. But the more devices the more complex in. Yeah. That's something. I think would be great. But maybe not applicable to everybody is it going to be able to track. Martial arts moves like we'll be able to track a double-leg take down or roundhouse kick or anything like that. Right now, you can program it to do anything. I'm you put it into kind of a learning mode on your app, you do a few motions you name it. And then it can can basically compare you to yourself in that mode. You can try and do perfect form and measure your form. Relative to yourself. But if you have shitty form, you're comparing yourself to shitty for exactly that doesn't know any better. Exactly. So what we're doing right now, which which will be a little bit of a lengthy process is defining a library of perfect form for everything that you could think of and then this, you know, this is going to unlock Telehealth and tell the training when you have something like that we can do remote programming and have been, you know, be monitoring people's neuromuscular function thereby mechanics completely remotely. So that's that's really what we're going towards this is fascinating stuff. Man. You know, there's always been several aspects to getting a fighter ready for camp has always been their skill set. What what they're good at specific training for that one individual opponent that they're going to face and then all the strength and conditioning. And you know, it's usually thought of as you know, weights and sprints pliers on all these different things. But I feel like this is probably the next step. The next step measuring all of your all these variables that you're talking about. And and seeing how your body is at any given time. So that you're not just. Guessing whether you're peaking your scientifically peaking exact, man. I mean, there's there's just no room for guesswork and subjectivity, you know, at this level, and technology doesn't there's no need for it anymore. So we're just trying to let people know shit like this is available. Right. So we're developing it, and then the end goal just to make it extremely user friendly. Right. So you're doing your velocity based training. And it says stop, and then you rest, and we're using your heart rate variability to tell you when to go again. So like, you know, Z's stop and go for your your period ization and things like that. So the technology's here now making it actionable recommendations for the individual that can understand is kind of what we're moving towards this is awesome stuff, man. Thank you. Yeah. We're really passionate that you've only been around for such a short amount of time to get your ready have world champion. Oh, I know man. I feel you know, there's times where you feel like you didn't deserve the opportunity because I'm new to the field. We obviously work our asses off and everything but the for Henry to put the faith into us. You know, this was a world champion camp. We're company also we're not even open yet where this. Probably have one of the best acceleration for a company. That's never seen the light of day ever. We also a few other sports as well. But yet for him to give us opportunity, and you know, we felt like we owed them something. So we we worked extra hard. Centrally. Put our entire company on hold for eight weeks to go help him out in it's paying dividends. Obviously we're here right now. So now, are you guys going to be open to the general public say, the the the average girl or guy who does say ju jitsu tournaments and wants to get in the best shape of their life. As you're going to have products for them and service where they can sign up for something. Like that. Certainly right now, we are already open in terms of diagnostic testing. So you can come in based on your sport your goal, whatever it may be we have customized diagnostic packages because some assessments just aren't applicable to some people. So we customize your assessment, we basically tell you what you're good at what you're bad at then if you want to develop a program that's a little bit of an upcharges the real goal there is to be able to do completely remote training completely inhouse training, and then any level of. Hybrid training as well. So right now, you know, what the world needs the diagnostic testing the data. Where already ready to do that what we're building? Now is the process he's a being able to use data put it into recommendations. And then scale it's hard to teach somebody, you know, everything that I do. So we're building the, you know, the the softwares to essentially replicate ourselves, my my buddy and the other room. Andrea Hicks, one of the best strength and conditioning coaches in the world these guys will attest to it. You can't teach people what he knows. So we have to code this into a software a lot of if then type stuff, and then this is able to be scalable to everybody we want to provide this training to to people, you know, the average Joe trying to lose weight, you know, the weekend warrior, the jitsu everything we want to be able to provide this everybody. Everybody deserves this type of training that's minimal risk of injury high yield return efficient. That's what everyone's looking for. And that's that's why the people are getting fatter. There's there's no good positive reinforcement out there. And there's no clear roadmap. How to get to where you want to be. We we put together like, you know. It to Google maps. Everybody knows their end point. They know where they want to be. But it can't tell you where you're unless you know, exactly what you're starting from you have to do this baseline assessment in though. Sometimes it sucks really understand. How fat your, you know, your body fat percentage and your metabolic and risk. You your insulin resistance and things like that. But you have to figure out where you're starting from where you want to be, and that's how we develop a roadmap. So getting people, and we believe this is this is the way of kind of making our way into the healthcare system as well. That's our end goal as a company people to provide integrative fitness is what we're calling taking little pieces from all the different methodologies of fitness. Like we bring meditation and yoga into our practices. Well, so little pieces of just about everything and be able to provide the everybody that that's what we're doing. So in the future when you guys are open. You're not totally open to the general public yet. Right. Correct. Yet. Eight months would someone have to come to you for the first initial assessments, and then possibly be able to do the consulting either online or through through the application. I mean, there's totally different degrees. We have one hundred percent remote kits right now. There's bad as you can do on your ipad, like biomechanical assessments can find your joints and things like that. We can send this to you. There's a lot of things that we want to be able to do one hundred percent remote for the most complex assessment. You gotta come in. You gotta to veto to max assessment. We can't send you a metabolic cartons. So the goal is to get people to just come into the facility, and then do remote programming from there. And this is a, you know, our concept is to put these diagnostic centres and possibly the attached training centers as well. And just start providing these everywhere because frankly, if we just went the diagnostic Jim of the future out, it could be five six hundred square feet, low low overhead facilities that are just really efficient. You know, just putting people out collecting data left. And right. That's amazing, man. Well, what does it been like for you to make this gigantic change into basically be like Ivan Drago pretty much? That's that's pretty much. How is kind of how it's kind of been like we took in the the I haven't drag. Approach probably more than the rocky of pro. You know, I think I think Russia's kind of tend to use science a little bit more than their training. So to me at first it was almost like Madam. I'm going all in on this especially this cap against Dimitrius. I'm like God, I'm going limit. Like, I'm gonna have faith in in the science. I got one hundred percent. I'm gonna do everything. According to even even if even if I don't want to and that's I think it just I started seeing my body change. I started seeing like the coaches kind of daft with like, okay, mass scientists in the center of this whole cat, and I saw the change. Oh, and I've never felt so recovered the night that I fought to meet you. It's just like I've never felt so good. I'm thirty one years old and they've been cutting weight since I've since I've been a kid. So you felt a big difference through the entire camp. Doing this kind of through the entire camp would trip out. It'd be like people were like nine committed your suicide, do okay if you're not doing this come in doing that. And you would have to saying how can we not doing what specifically? Oh, no, just just more work more more pad work more more sparring rounds. Like things of that matter like the kind of like the gladiator stuff. Like, no, it's it's it's gonna go, according to my heart rate, it's gonna it's gonna go. According to what will my one those what my train of my windows of opportunity of training. Are you know, people kinda mumbo jumbo talk. Yeah. Like, nobody knows the day that I wake up the day that I trained like nobody knows what's going on until until until the data's gun in the hands of Kevin Neal force one. And then they'll they they determine this is how many rounds this is how how we're going to kind of peak you for your fight. If you standing on the sideline when he's sparring in rounds and stuff and more slow patriot like coaches like you can't do that. This is fighting. You can't try and control your heart rate while training now this training for fighting. Right. You know, so we're we're telling constantly telling him to train less slow himself down. There was a little bit of clashing there at the beginning. And then they started to see the body composition come around and started to feel his power and everyone kind of bought into the process, but it takes a while. We're now we're redefining in understand that there's some pushback. This is such a universal concept when it comes to strengthen conditioning coaches, it's being discussed over and over again nowadays people are doing too much you doing too much and your body's just doesn't have a chance to recover and even though. You're getting in better shape. Ultimately, you're not getting in as good shape as you could have gotten if you did less, which is so counterintuitive for most people. Yeah. And that's kind of how that's that's that's kind of how I used to train so hard, but I used to get hurt a nice to have back spasms kicking. That's how hard I would trae like my back with Louis go I just kicking throw one kicking they had to pull me off the gym in a stretcher. You know, and I had those problems because I had just I really I didn't you almost train according to how how how the schedule is rather than. Okay. This is this this is the opposed today. Because this is this this is how your stress levels or. Yeah. Like relaxed and then at times, you're gonna go hard. And it's it, it'll spike you it's it's crazy. Well, that's the crazy. Contrast rate is between this championship mentality that just wants to do more than anybody push harder train while everybody else is asleep. Put your body through more than anybody else's willing to do because that's what makes a champion. And then someone like you comes along goes. No, that's more. That's fucks. You up to slow down do less less rounds? Move slower. Yeah. Exactly. I mean that was one of the biggest things I told me if you're not sleeping eight to ten hours a night when you're putting your body through something you're doing your body and injustice, and you're not gonna make that up -tations when we're out there training. We're breaking our body down. It needs this repair. We need. Activate our Glymph. Attic system, our brains waste removal system as well. So we can go learn some new things the next day as well. So if you're not sleeping, your sub optimal. Just like you're not properly hydrated and things as well. This all comes down to the cellular level. You know, nervous system base approach. Now, are you taking melatonin or anything to ensure that you go to sleep at a specific time? Do you time your sleep schedule? How you wargin ising that? Yeah, I think and that's another thing even at times, according to win would go to sleep because that times, you know, how you train late and sometimes you come back, and it just takes you ought to go to sleep. Yeah. So even then it would be like all right when when Henry is ready to wake up when it obviously if I don't hit my longer than I snooze it a more lucky they can allow me to sleep extra two hours, which is important. Yes. So it's like the is kind of like we'll Floyd does flow. We'll be a hail wake everybody up at three in the morning. But there's no scientific to flow is doing to us. It's like, hey, let's we have to pick today. So. I've always wondered if there's science behind it. And he doesn't talk about it. With floyd. Things. So. Yeah. Like when he drinks, a Pepsi after workout. It was like wonder they told him to do that to replenish his body with a ton of sugar glycemic carbs right after that's the only time. It's really good forty five window of insulin sensitivity, I do believe that one technology. We what we're on the sleep thing. One that we're utilizing for Henry just little light microcurrent here, your temporal lobes, and it's proven to increase serotonin and melatonin and decrease cortisol. So we're like manipulating biochemicals, and it's very natural way of making you feel drowsy. What time are you do that? We would do that immediately following every rigorous training session to kind of like negate inflammatory responses and things like that, you know, get you back into that anabolic phase as quickly as possible, and then I dearly right before bed every single night. Did you feel like a science project while the ship was going on? I did I did actually did a presentation on me in Russia with Roman with the with the scientists that have it they use CPI like they tracked everything according to the omega. With the device that we're using. And he was able to kinda show. Hey, look, my system might you know, this system does work, you know, it's just like people were kind of just tripping out. So I went out there did the whole presentation with in Moscow. And everybody was just kind of just like everybody was kind of like. Wow, amazing. Someone looks kind of scratching their head. It's a little like, Dan. That's that's cool. You're able to kind of see how I peak for this fight. And how was able to kind of survive firearms? The Russians of really been pioneering this type of training for quite a while. Specifically, the type of training like that Pavel Tatsu lean uses like where you're using way less energy, you working out way less, but you're getting better results from it. Like, there's there's a lot of thought processes that have have been leaning in this direction from a lot of really high level top coaches for quite a while now. Yeah. No. And it's cool to see because I come from a traditional sport where you put your head down, and you go that's. Wrestling multi think they're very very alike in that sense. Like, they're very traditional like the hardy go the more you push through injury. The you know, the better you will become. Yeah. I also think that there's something to be said for that though in terms of mental strength because one of the things that wrestlers have that is it's not just that they have a great skill and being able to manipulate bodies. But they also have mental toughness. That's at a level that I don't think you get from any other sport. I mean, I think there's a lot of pro athletes, even tennis players that are just mentally tough, tough su- people just know how to win they know to push themselves. But I feel like wrestlers are on another level because they're always tired. They're always overtrained. They're always dehydrated, and they're always working out with a bunch of fucking savage. They're all the same way and everybody takes pleasure in being miserable. There's something to that. You see, man. I've seen thousands of fights. You see there's something about wrestlers. They. Have just like an extra gear a high level wrestler in particular has an extra gear that a lot of other fighters. Just never developed. Yeah. It's it's almost like I tell people wrestling's not it's almost like not a sportman. It's like a culture. Yes. It's like, you're just you're in the culture of wrestling. And once you have that it's almost there's an honor to there's a warrior to it like an it's it's it's our which is at the world championships Joe, and I can tell you man, the best athletes in the world. I was just a Budapest, Hungary. And I saw kost Neider and all these guys compete it. I'm just like, man. These are the MO these are the best athletes in the well, this is the hardest shit. He'd been being could ever do if you're the finesse and the strength and the power Wilton Volvo in it becoming a world champion and watching these guys go through this freaking talks just a tough the toughest tournament in the world. And it's I I think what we do in him is fun compared to competitor wrestling. I really do. I like that stuff is like man that stuff is hard with these guys go through a win a tournament. Like, it's the way cuts the, you know, the they don't get paid a lot of money, right? These dudes are little gloomy all each and every one of them is all glory. There's no financial reward at all. That's what's fascinating about it. But it's just interesting to me that I think you kinda need both in some weird way your mind needs to develop this layer of toughness that wrestlers have. And then I think once you've developed out, then maybe I think your approach Kevin is like apple. But I think that until an athlete has that indomitable spirit until they have that sort of that iron will that a wrestler possesses. It's there's to make a champion. I think you need many many things, but I don't think you can ever discount that ability to work through discomfort the way wrestlers. Have. I don't think it's wise as a professional athlete at a championship level to compete compromised. Agreed. There's the intangibles the stuff that you just can't teach you can't quantify. So we do our best to quantify as much as we can. But yeah, I mean, I completely agree. There's you got to put in the time in the work to learn the skill at some point. And then once you know, it, it's automatic skills master. That's when you can kind of take it back. I'm gonna I'm going to agree with you. Joe? I think I'm going to agree with you. And I think the reason why this works for pretty much every may fighters because we've all been through hell, yeah. Like an order feud to see and believe in scientists you have to go through how to understand like, Amen. The hard way probably is the best way. But when you were talking about your your the feeling that you had in not wanting to ever feel the pain of losing again that feeling that you had when your ankle was going out. And that like fuck this. No, no, no. I'm not doing this. I'm going to find a way out of this. Like you almost have to. Experience lows in order to have that. And I feel like that one of the things about wrestling that makes it a sport that creates so many fucking savages is because you go through so much shit so much hardship. So so much difficulty that you know, if you had science based wrestling programs the way you're doing science base camp, and you went in, and you know, said everybody got slow down so down. You know, you're going to hard slowdown can't run up hills today. You know, you're you're you're DC brainwaves or wrestling coach like shut the fuck up and sit who is this asshole. Dan gable? Brought you in a camp, and you guys are running around doing all this stuff. He'd be like what like what are you saying? Like, this is how we make champions. Yeah. Yeah. But like I said, I think you hit the known ahead. I think it's for to me the way I would see it as like you have to kind of go through hell. Because you had to go through that callous through that burn. But I feel like especially may a lot of athletes or even at least just in general, they everybody buses or buts. If you're an elite athlete like you'll you'll always trae, maybe not the smartest way. Yeah. You know? I it's. Yeah. I I guess you could add more to to your train or take away less. If there's a there's a fine line to the other fine lines. What's fascinating to me? Yeah. I one of the things that I love about him is that it's so broad. There are so many skills that the approach to success is different with every individual. And you have to find what that approach is the approach to you for your for you for you to achieve success is going to be different than they approach for a different athlete. It doesn't doesn't have the same skills that you have. But like Anderson Silva, perfect example, he's not a wrestler. It's going to have a different different approach is there's going to be different things that they work on. And training is going to be a different mindset is going to be a different way of preparing. Right. Right. And and it's all according to everybody. According like, nah, it's I think a lot of things are cookie cutter. Like looking at it the way. Now, it's a lot of things have have stayed even in wrestling like just over tradition. You don't like bridging like every time I see people bridge in the way stretched do that shit so bathroom they'd be doing like these like springs on their head and just Kevin how about how 'bout his bridge and for you. I mean, I I wouldn't recommend it. I mean, but Mike Tyson always looked bad ass and he's doing it looks pretty bad ass. Have you ever fucked around with the iron neck with the iron that we don't know about that? I got one back there. Things you gotta try this your videos, that's definitely one of the missing links by a lot of these wrestlers get hurt that, you know, stability, the, you know, posture issues that come associated with it as well. He's got into strengthen their necks. It's a halo. You put it on you pump it up like a Reebok pump. Remember the? Yeah. You pump the sucker up so tightens up on your head. You put a chinstrap on. It's got a bungee cable on that set to fifty pounds back up. And then there's resistance on the halo. So it spins the resist the halo has like you could tighten up or clampdown or loosen up the resistance, and you do these exercises like. He goes sideways do like like like loops back and forth. It's it's fucking bad asked. Yeah. That's that's crazy. I'm excited. I got a. Yeah. You got to sign that waiver is that. Waiver. Hold of that. Run through walls, all the. Then the flow tank. You wanna waivers for don't you lose? Your sensory merging the float tanks. They're pretty bad ass. We study those quite a bit for the nervous system based stuff. We're we're building kind of our own sensory immersion like mindfulness room of the future as well. All the walls, LED screens. He you can put yourself fully immersed in any environment. And I it's going to be pretty bad ass mindfulness. So overlooked in these sports how how important I know. You're you're a meditation guys. Well, it's getting your mind right is invaluable. Yeah. You were saying the meditation yoga is also a part of the preparation that you guys employ one hundred percent. Yeah. I mean, it all comes down to you know, when we're doing our warm up training and recovery, it's all mind and body. So his up is going to include like somatic sensory reaction testing. So imagine like a wall, and it has different lights on it your act quickly as you can soon as they light up, and I say art athletic comes up red use your right hand and blue use your left hand for invoking cognitive decision making processes, the we have you seen on one of these shake place, appropriate receptive. Play. Now, your vision, your neuro, muscular, appropriate receptive. Everything is warmed up everything every part of your brain that's going to force output absorption, and so on then we go to a more traditional warm up whatever that may be we do a cognitive training. We do physical training more from a functional aspect, and then soon as you're done, we'd get you into a mind based recovery as well. So we get you into yoga meditation that technology were playing with right now that manipulates your bio just about everything, and it's mind and body every step along the way. And when you do in yoga you doing yoga to increase mobility doing it for the mental training for both like a definitely a little bit of both. We Andre Moore leads the yoga what what we're doing over there. So he'd be better to ask specifically, but we believe it largely for nervous system in for breathing. One thing we've really talked about as a diaphragm Matic, breathing and yoga is really a common virement to be able to focus on your breathing. But does that mean diaphragm Matic? Breathing from your diaphragm. This is how we're all born breathing from our diaphragm and just you know, eventually we ended up breathing from our chest, which is very ineffective for metabolic efficiency. Like, what is this like when you see like the women Hof guy? He's right breathing from his gut here, and that's like engaging your core. As opposed to just like your chest. You're actually getting deeper breath. You're encouraging like course the ability and things as well. It's better for metabolic efficiency. So when you're actually exercising its better for delaying anaerobic threshold buffering lactate things like that as well as keeping the nervous system com as well. Do you think there's any benefit to breathing through nose and out through your mouth, or is that I I'd say it's in on an individualized basis. I think the best thing is to not think about your breathing when you start thinking about it, it can kind of get fucked up. So if we encourage diaphragm medic, breathing without this technology realize is actually even though when you're utilizing the technology, you're just breathing in and out through your mouth actually encourages in through the nose out through the mouth when you're training. So I mean, I'm not an expert specifically on that. But it sounds. Yeah. I think there's definitely some performance advantage to it. I I wanna talk him a may now Joe thank you, Kevin and appreciative and this guy will his cO. Kevin. Thank you so much those amazing and tell people where they could find out about your company, and what your website is our companies in Scottsdale. Arizona. The website is neuro force one O N E dot com. Check us out. All right. Thank you. Thank you, those very informative content. Shinri son Henry's now, become the standard. Because like he said that Romo for the performances to debt did that PowerPoint presentation for UFC Moscow. He told us he's the first athlete that ever did eight weeks, they have eight weeks collection of data so Henry's now become the standard of this system that Roman had near force one and all the data put together the first time ever that an athlete actually stuck to the program for eight weeks. That's fantastic. So for you. Now, you got the title. And there is talk about you fighting for the bantamweight title against champion T J dillashaw. What are your thoughts where where are you at right now? What are you? What are your goals? It's a beautiful town to be to be the Chan. There's there's there's tons of tons of options. Joe where's your contract at right now? I have I still have a boss having fights left. You know? But I'm wondering we're gonna renegotiate. I think more likely that teach you five might might happen. God that t- fight might happen. If you know if it's going to be done with the with the flyway division. You know, I think the cat's out the bag, and you know, they had had mentioned that to me. So, hey, you know, we we want to take you up on that offer view a challenging to go up against TJ. But this is what this where the company's been thinking about for a while and TJ's down for two. I don't think so I think TJ wants to come down to twenty five. No, I think I think that's kinda like the steel. The point. Now, would you rather fight him at thirty five? So you can get an additional title. Or would you rather fight him at thirty five because you don't have to wait or I don't I like, both ideas. I actually kind of left it off to him. I says, I don't know. But I I wanna fight you. They wanna fight TJ. I wanna I wanna go out to the next best thing. And that's I think that's him. You know, if you don't mind fighting a twenty five or thirty five I don't that makes it easier. Yeah. That's definitely hey, let's see that twenty five. Let's do that thirty five bullets. Let's fight man. That's what your your mind. Is right now. That's your number one goal. Yeah. Yeah. And I believe TJ wants to fight me too. I think I think you know, beating Dimitrios kinda that's going to help his name. You know, you know, I guess for both you can see. So now, the Dimitrius has left the division gone off to one FC to get. Well, where where do you think the division is right now? I mean, I is that one reason like if you one at thirty five and won the title thirty five would you consider dropping the twenty five pound, title and competed at thirty five or would you rather stay at twenty five? I would I wouldn't mind I wouldn't mind dabbling in both. I mean, that's that's kinda kinda broad. But you know, I won't point you do get tired of cutting weight, and I'm kind of way right now. I'm probably about pi fifty fifty one. I mean, losing fifteen pounds is way better than losing twenty five. Yeah, I'm a little I'm a little bigger now. Because because of that reason I might I might have to fight at a Batum. Some kind of I think more Lacombe might happen. Batum way. What people don't know is that actually Henry almost TJ when he was the chant when Hannah Barau didn't make weight his first ride in the UC. He make wait with two hours later. Henan Barral didn't mayton make weight and they were looking for somebody to go up and fight to Joe Soto fought him Joe soda fought them. How many was the number one option but Henry hit already declined to? He said he wasn't. Finding jorgensen. But now here we are three years later back. Now, he's got the tent. He's got the belt TJ came back and won the belt was doing these guys been beef from for for a long time. So that's ever since the first day he came into the UFC him at TJ been at it. And then on the ultimate fighter ultimate fighter twenty four. They had a Dwayne bang was the coach those like a little beef with Henry and bene- Vitas his team benefit as coach. So it kind of goes way back. There's a bit of. There's a bit of animosity to top of everything you are very goal oriented guy. Do you do you have your career mapped out in terms of like when you would like to get out of the game? My do I think about it a lot because men I will be honest with you, Joe, I've I've accomplished everything I've ever wanted to you know, in my career like I've always had I had three goals. And I'll just you know, my number one goal was just to be a good person and good father. Good husband. And then after that was being an Olympic champ. And then and then and then eventually USC champs. Everything's kind of. I I've done everything in that. I've ever kind of set my mind to you know, those are the two biggest the two men. And I don't see myself fighting for more than for more than maybe three to four years. The only thing you really are in this rare space where you have the possibility of being considered one of the greatest combat sport athletes of all time you already in the mix right Olympic gold. Medalist UFC champion. I mean, you you have this very rare opportunity for incredible greatness. Yeah. I think for the most part I mean, I'd like to eventually I mean, I do a lot of motivational speaking I've been doing that for a while Joe is spoken for like the biggest the biggest companies in the world. I mean, the Coca Cola like TD Ameritrade of Proctor and galley billion dollar sound by Kroger. And the kind of you know, they use me for for that reason. And I really enjoy doing in a plus you get full pay. Don't have to get like kicked. Yeah. Get lake cook hit that nerve the drunken monkey gotta do all that. And it's just quit. It just go to kind of should the, you know, the whole underdog stores. I love the people do do that the companies have the the the mindset of bringing in champions, and people that are extraordinarily it whatever they do. And speaking to these, you know, these people that work for them and explaining that motivation is gigantic motivation is such a huge source of fuel for people in all walks of life. You know, the have a guy like you come in and talk to a company can have a really big impact on their creativity on on how they pursue goals on all all kinds of different things. Yes that that's so anyways, that's kind of where I kind of. I can see my life kind of heading to eventually. I don't think I I don't think I think be a fan of the sport. But don't think it'll be involved in either wrestling or fight as much as I think would not as a coach not as no it's too hard. You'll like look at all these these coach. It's too relationship being a coach is you're you're in a relationship with with your athlete. Sometimes you go through these breakup. And so tends to athletes don't give you what they wanna give you an it's just the it's a headache. And they see that with I see that with a lot of you know, I see that with him. And I'm just like, I don't know if I want those stress level. For guy. Like, you you you get across guy. Like Henry you hit the goldmine. But you could get across the guy who is a really talented guy that's flake and those two to me personally this plenty of those. But to me as an analyst as someone who watches fights. They're the most frustrating because there's some guys that I see God damn that motherfuckers. Good. He's got potential if they can do things inside the octagon, they do things. I I'll see guys in the gym like I'll go to gym watch guys train and see the guy I go this motherfucker could put it together. Like this in the cage the way you see when he sparring like some people just artists, but the anxiety of competition, and all the factors that come involved disciplined, the consistency. All the things that make someone a great fighter. Sometimes there's so much seventy different things that make someone a great fighter that wind up fucking them up. When when they. They actually go to compete, though, the recklessness impulsiveness that actually makes them good. Also can wind up tanking them if they don't sort of forge it with with with some sort of like severe discipline. He there has to be a training the mind to an I think that's where people are skipping. And I think that's that's where you have to understand the philosophy appeared. Like you have to you have to be right up top. You've don't right. You have to understand and know who you are as a fighter as a person, and you know to kind of. To be stable enough to perform at when when it really matters, you know, and if if you don't have that you can be as talented and gifted as you want you'll you'll never make it. Yeah. We'll see those all the time. Like guys practice, man. They would tear me up and it came to competition. They would just roll roll over like fish. It's weird. Right. Yeah. It's crazy. I'm like, yeah. It's weird as you're coming up, and you see those guys, and you you realize like man, there's there's something missing. And then you you you you're terrified you're going to see that and yourself, and I think it's the embracement of embracing pressure is something that you don't aglet something she don't shy away from something that you don't allow them to damage you, but attendant bracelet. It's a it's a, hey, bring it meant bring because that's what it is. It's the pressure that people feel the reason why they can't perform it's what makes champions. I remember when T J dillashaw, I fought Hennion Barral when he got into that octagon, dude. He looked like he was born. He was loose as a goose and I saw them. I'm like damn look how loose TJ is like this is a world title fight. And he's switching stances and giving them looks. And he looks fantastic. He just looked loose. And then boom, he hit someone that big over. Handwriting next thing, you know, him Barral getting fucked up. I mean that was what TJ thrives on that kind of pressure. He lives for that kind of pressure. Just like you do choose why. Let's do I want his head on I want. I want his head on a spike. I wanna make I wanna make some snake shoes. Snakeskin snakeskin shoes navy suit. He might be big enough for me. What a what a fight it'd be offense. Two minutes, those champion versus champion encounters are always so fantastic. And the reason why it's cool twos. Because we're both in our prime to teach us probably a couple years older than me. But even when they meet just like, dude, I'd be Dimitrius in his prime. Like, yeah. It was a close fight. But man, I I can say I beat him in his prime in this try almost like there's no doubt. But it was it was because of the game plan, and you ended the greatest winning streak in the history of the sport. Right. British championship defense streak in the history of the sport. And then on top. I mean number has the greatest winning streak in the sport because you know, still undefeated, but as far as defending the title DJ was number one. And again, you did it to in his prime. If you look at the way, he destroyed Wilson Hayes of you look at like, I mean fucking everybody, man. Everybody just he's a monster org degraded mission, and that was the crazy shit of all time. We fucking suplexes him and catches an arm bar on the way down get the fuck out of here. And he told me does that and training all the time shit. I. That humans a wizard the wizard one of the things that I did that was kind of on the conventional unconventional for this camp had them video it we obviously we scouted to meet your Johnson. But then I went back and got every one minute clip of Matt Hume's. Interval between rounds? So twenty five fights. I have the one minute what he tells them how he adapts is in changes and one of the things I noticed that he always went to wrestling. And when he always went to wrestling he sounded like it was automatic. All right. So this room we're going to take him down. And we're gonna work it was always automatic. And when it went into the fifth round it wasn't automatic. You could hear him say you could try to take him down. If you want. It was kinda like that the way he said it when I went back and watched and I was like we got him and going into that fifth round one of the things that we talked about subliminally and mentally training was when we went Henry was just putting the hall of fame. You know, he which has never been done at such a young age as a wrestler as a wrestling wrestling hand when I was at the restaurant hall of fame Nate car who is also one of the greatest wrestlers ever. He told me he said, you know, what Eric when I wrestled Kenny Monday, and I lost him in the big tents. I knew that when. I went out two weeks later fight him in the NCAA finals that it might come up that that that ban. This guy just beat me. And he goes to a had a book. Actually, I think he said his wife made his book, and he put all the positive things that that make car had done and all the articles and she made quotes from that. And put it in this book. So he gave me that I did. And then I did that. So Henry was put in the hall of fame that night. They had a video highlights had Terry brands as coach they had a surrogate Bill laws of Kenny Kevin Jackson, some of the greatest all his coaches saying stuff about him. And I took that. And I put it in his book. And it kind of like I read it to him every day and the kind of like a happened in the fight one of his own quotes. Who said I'll gotta go in there and kill and be ready to die. And and you know when he got that leg injury. You know, he was ready to die. He was ready to keep going forward. Yes. We adapted and went southpaw, but some of that. Stuff from the book came exactly true start fast, and and finish even stronger compete with passion and purpose. And this is what I said to him right here and the fifth he's in the data show. You the? Does this is what I told him going into the fifth round? When we was four. Let's see let's see the tear shit. Let me say as less. Throw Henry burn the ships take the fucking castle. Let's take him down hurt him on the ground. If he gets back up knock his ass out. And that's what I told them going into the fifth round. We had one or two we should the messenger. So, you know, it's just something that I was ingrained in to them every every sparring session. I had something set for him. But this time going into the fifth round against DJ. I wasn't sure if it was to to two or fee needed a knockout. How did you feel? I thought it was too too. I thought it was too too. I think I think the I think DJ from the interviews that I've heard I think he felt like it was to go into fifth. Yeah. We thought it was too too. When we were watching the five bucks dams as close as it gets. And again, Jill I wouldn't I wouldn't like echoed. I it because it was such a close fighting. I'd I'd I clap for Dimitris tooth would them the the fight. Like, I I know it was close. What did you way was actually I was actually a pound lighter than than the Meech unless you it? Yeah. You look bigger really did. But that's again. That's that's one. That's kind of where they the way they placed like my Mossel like it was. That's why look bigger. But no, it was a pound lighter. Dmitri's johnson. Did you win that one forty-one? Wow. This because when you saw you guys standing together in the octagon, you really did look bigger than him. Really interesting. Yeah. Yeah. So I'm not I was I was leading into his people fly. Done saying he said it twice. He's so big. He's so strong. He said it twice in his post interview. But that's wrestling strength. Right. Wrestling traits just a different kind of strength with. It's sometimes it's not even stricter to leverage. Learn how to use to tippy toe things and how to use your way to to pressure opponent or to take them down for sure. But there's also strength. I mean has some strength that wrestlers have anybody's ever would wrestler knows that. Yeah. I guess you're see the transformation that he had from the eight weeks from the beginning to the there's a documentary. These guys film the whole entire thing. You put in the documentary. Oh, yeah. We're I think we're gonna put it out sometime in the I think in the spring, but it's going to come out, and it'd be bean it's going to be it's going to be. I think they we're gonna try to pitch it to tuneup flicks. Nice. The messenger. Yeah. The mess and they'll forget as not only was he fighting for the title. This guy was fighting for his life, only, eight months before in the Santa Rosa fires. So very inspiration. Crazy fucking story itself. You actually burn the bottom of your feet running escaping a fire that snuck up on you like lightning speed. Yeah. It was it was it was a craziest thing that's probably ever happened to me. And I've done some crazy thing documented in the pre show like they showed like all the damage to the area where you were living. It's fucking terrifying. Yeah. It was crazy. I anyway, I mean, I guess I guess I guess this is where people share their stories, right? It's yes. So this was about a year ago now. So this was about a year ago. Now, I got invited to this event with raising risen raising money for kids and cancer and everybody in there every every big celebrity gets violent Jerry Rice Barry Bonds, like the like the big. A list celebrities and everybody was there, and we had a fundraiser that night, and you know, wine country, and Santa Rosa, California. You know and everybody, you know, everybody had to drink or whatnot. You know, I had I had a couple of glasses. Maybe had a few glass of wine, but I don't I don't drink one. But I had a few glasses. And I remember I told her, but it had mostly guys and it was close to about midnight. I was like I trying to stay with these people. And I'm trying I'm trying to sleep because I never drink wine. So I go to my room, and and then I shower get into bed, and I remember right before I went to bed. I remember I I saw the flickering of lights, and I just thought that it was weird. This is roughly by time. I got to my hotel. I showed I saw the flickering of lesson. You think anything of it? And I pass out to thirty hits two thirty in the morning hits. And I'm just. I'm just you know, I wake up because I hear the alarm, you know, kind of pop off at the at the hotel. So now, I'm here in these alarms starting to go off. And I've checked out checked out in front checked out a through the window and check lobby. Nobody was moving. So I was like false alarm. So I got pull over my head and every step to the lower that happened about two thirty four thirty comes about this time on a week. I don't Waco because the Waco because of the smoke. My coughing. I'm I'm like coffee on the smoke and efforts. I I thought I was dreaming so wake up and at that time. I had I had you know, I slept in my town. That's how tired I was. And I got up and go to turn the in the lighting turning on. And then I go through the wind and tech that window, and then she know what I see the car right in front of me on fire three four of the hotels. Like, I was probably about five rooms away from getting hit hard. Like, I'm talking about like like fire KOMO out the window like that. And waking up to this like thinking, I'm dreaming. You know in a towel. And the lights everything was dark, but I could see everything like like the roof started getting hot. And I couldn't I couldn't hold my breath in the moist looking for my my shoes. I couldn't find my shoes, and I bump into my slacks that I let them on the ironing board that the night before I put them on. And I I grabbed the grab my phone. And I jumped out the window ended up the one that jumped out the window. My right foot catches on fire. Right foot catches on fire fast. And I'm looking kind of I'm kind of you know, trying to put it out. And it's crazy how I can see how people could catch on fire rule quick. Because my my right leg was like foam. It was crazy. Wow. So I jumped on I start walking as as I'm walking them seeing like this the hotel front of Lewis was all in sticks. The whole thing was just sticks. Like the fire had just ate that thing up. There's a building front of meal on fire like I'm just walking through the streets going up the hill and just thinking like that. Be a horrible way to die Horowitz die. And I got I got a bird's eye view when it was on top of the top of the hill. And then I saw there's a cop down there. There's a cop down in the middle of the free. When just we know that that's where I gotta go. So now running fat and I've seen this brushfire. Kind of come along. And just I'm seeing like California like just catch on fire like completely like through. My is that you over the first fence to get to the freeway. You know, no problem jumping the second fence. And then the third fence it was a very like a flimsy kind of fence. And I remember as I as I jumped out of his snag like part of my snacks. Keep in mind. I was I had the only thing I had on was slacks, commando, flax. No shirt. No shoes like out in the code in California. And as that flimsy fence has jumped out that last fence it like cut like a part of the fence, I grabbed my butt, and it just it it cut me open. Hard and tore like half the lakes and now I'll full full of smoke. My right Foot's, burn. And I'm pretty much half naked in the middle of the for you. Right. So I see the cop car, and I go up to the cop car, and as I'm going up to it. I'm sorry. If we can Cup car leaves. Oh, like fucking just scrambles. Just like, oh my God in seen as that cop car left. I remember seeing like this big as diesel coming towards me and every get into the middle of the free wing kind of you know, waving my hands. Like, you take me I died like this hit me. And as it got closer Sowell's a fire truck, and I get rescued I get rescued by the firemen. It put me in the fire truck, and they're just kind of looking down. Do you just you just survived death? You just survived because I was blacked already smell like a marshmallow did anybody dying the hotel fifty fifty people died in? In the hotel on. I'm not sure if anybody died at the hotel, I hope not, but I could see how fifty people died in. It was a worst. No, yeah. Fifty people died fifty families like it was it will sad to hear my. So just happen quick. Those fires come so quick people don't realize before it's too late. And then there's no escape route. And I think the reason why because I think people had time to get out. And I think the reason why fifty people died is because they didn't take the alarm like me serious and actually noticed too late because that that spoke will blind you so you think of going into the right direction and actually know you're walking into the biggest fire in history Jesus Christ. So so that had happened like two most before I fought Sergio bettas in nice still fought them like I trained with two socks at my just with with the with the wrestling shoe, and I just stuck it out. Because I pulled out the first fight with us as I I gotta make it up to you and told them I says, I said you want then you kind of call me on it was like, dude, I'm gonna fight your regardless. Now with with with with the first degree burns on my foot or I'm sorry. Third degree burns on my foot. Glad you made it, man. Yeah. The here. I two thousand eighteen UC. I'm glad you made it and I'm glad we could do this podcast. Thanks for doing this, man. I really appreciate it. Yeah. No for sure. Thank thank you. Joe been a been a big fan of your show and. Hope you guys got some good insight on the messenger and captain America. We certainly did. We definitely did. And and Kevin as well. Yeah. Well, thank you. Thank you very much. Thanks. Thank you. Bye running. Thanks, everybody for joining the podcast. And thank you to my sponsors. Thank you to simply safe. Good. A SimpliSafe dot com forward slash Rogan. And they'll know that you were sent there by us. You will get a great system at SimpliSafe dot com slash Rogan. Go there check it out home security that does not suck. It does not rip you off. It's fantastic. Twenty four seven professional monitoring for just fourteen ninety nine a month. Simplisafe dot com slash Rogan. Thank you also to stamps dot com. Go to stamps dot com. Click on the microphone at the top of the homepage and type in JR e they will hook you up with a four week trial plus postage and a digital scale go to stamps dot com. Click on the microphone the top of the homepage and type in JR stamps dot com and enter J R and last but not least we are brought to you. By my bookie, go to my bookie and use the promo code Rogan to activate this offer. They will match your deposit dollar for dollar in time for the big fight on Saturday night between Daniel Cormie and Derek Lewis for the heavyweight championship of the world. So use the promo code Rogin to activate the offer. Visit my bookie online today. That's my bookie and don't forget to use the promo code Rogan when creating your account to claim the bonus you play you win. You get paid. All right, folks. Thanks, everybody for tune into the podcast. Appreciate the fuck out of you. Hope you guys enjoyed it. And we'll talk to you soon. Bye. Bye.

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Ben Askren, Henri Hooft

Ariel Helwani's MMA Show

1:04:55 hr | 1 year ago

Ben Askren, Henri Hooft

"Hello. Friends. It's your pal area Awani back with another Wednesday edition of the pod special birthday addition of the pod. Yes, today's my birthday. It's so great to be here with all of you. Getting set for you of C, two fifty one. Saturday night July eleventh. Mazda who spent can't wait for it, and we got two great interviews coming up I would the one and only been aspirin? Who of course is tied to both Mas with all suffered that record breaking Ko loss to him exactly one year ago this week and the man he calls. Mardi use men, so we'll get his perspective on that fight and the rest of two fifty one. I'm looking forward to that. We will also talk to the head coach over at Sanford in south Florida Henry Hoofed one of the best coaches in MMA head coach for Gilbert Burns, also longtime head coach for before he moved Colorado to train in the same facility as Guba Burns. He hasn't talked about that whole situation. All the drama surrounding it so I highly suggest you stick around for that, but I of course the reason why we're talking about all this is because the you have C. headed to Abu Dhabi this Saturday with a triple header title fight card with. With amazing names top to bottom amazing fights. It's you have C two fifty one. I can't wait for mas with all Vulcan off. St Hallway to John Although you won't WanNa miss this one have see two fifty. One is exclusively available, ESPN plus subscribers for sixty four ninety nine visit, ESPN plus dot com slash p. for more details, also thirty for thirty podcasts back with season number, eight heavy metals inside the Corolla gymnastics, empires, a groundbreaking seven part podcast series that takes listeners on deep dive into. into the lives and influence of Bela and Marta. Karolyi, the most successful and controversial coaches in USA gymnastics history to listen to the trailer scribe to the thirty for thirty feet on apple podcast. The whole season drops next Tuesday July fourteen on apple podcasts or wherever you get your podcast. Greg said about that also said about today's program. Let's get it rolling baby, and of course let you know. The pod may contain some language that's not suitable for audiences, so listener discretion is advised our enjoy. Own Back in your life on this Wednesday, July eighth two thousand and twenty. Everyone welcome back to the program as always. We Are Presented by Modell modell Oh s space. Ya'll for those that the fighting spirit and my friends three days away. You have C two fifty one July eleven, ESPN plus pay per view I can't wait. I'm so excited for members Mas Vidal Bulkin, Ski Hallway to I'm so excited by Yang versus Aldo. The return of thug rose page Vance so much to be excited about. This is a great card I can't wait first time in twelve years that are not at the early July card, but. I'm not down about that. Because this great, we got the fight that we wanted. We have so much to discuss with our guest today, so let's all waste. Any Time Ben Aspirin Up I. You know he's tied the Mazda on newsmen. You know he's always money this time. He's even manure than usual enjoy. I gotTa say in Twenty Nineteen. It seemed like we talk to Ben Aspirin every single week this year. He's been a little elusive. He's been a little distance allusive. Come on well I mean. Let's be honest. You're not really active anymore than you really talk to you about these only active on twitter. That's right, holy smokes. WHAT A hot take! You had recently DM Mexican underrated rapper. Come on, what do you think? You know he was great. I don't think he was underrated. Oh, I think he was rated pretty high. Okay? Okay I just don't feel like know I don't feel like he's ever in that. You know people put their top five lists I feel like they never ever include him. And you know I think you know. He didn't make everybody's list, but he should. He should make subways of course yet know you have been I. Mean if if I'm being honest, you're you're entering prolific social media master territory. At this point. You're doing a great job on social media. I guess you have a lot of time on your hands these days. Actually don't. We open our Ford v Wrestling Kademi. Spring and then obviously doing three or four podcasts, and coaching a lot. So Am coaching eleven practices a week right now, so you know a pretty busy, but obviously your social media doesn't take that much time. You have a thought frigging. Click it. Type in ten seconds and you're done. You're very good at, and you know it's amazing. exactly one year ago, today was one of the most memorable interviews in the history of my show you. Okay so July come on a well. I didn't think about that, but yes I do recall of course and you made that joke on twitter but I I feel like there was some truth behind like Oh gosh now for the rest of the week. Not only it's the anniversary, but Muslim steps up and he's in the news. Does it really bother you to have to see that all all the time over and over again? The flying the flying the knockout mostly scroll through it. There's very few times where I actually sit there and watch it maybe five times over the course of the last year, compared to say to the million or so. That it's posted so I, very rarely scroll through, but having that all my timeline, and then having to you know obviously you have see in other anime content people that I follow are posting all this week and just like you know I don't hold grudges towards that, but it's like a preferred not to see it if I can. Is it possible that you and Mazda are like buddies now I feel like you're actually I. Don't think friend No. Mutual respect now. I feel like there's no bad blood whatsoever. He enjoys you. You enjoy him. I feel like deep down. Maybe you're rooting for him. Because the better he does, the the makes you look, because if he if he turned out to your dud right than that of the knockout look work, I don't know I feel like. I feel I feel I. I don't think the him. You know how Hummers success. He has does not have any impact. It was one move. It wasn't like you know it'd be me. Fifty moves zero just one move and that was it. You know I did I didn't ever hate him. I I kinda I. was Kinda like in the middle of Mike some things that he does? As something's idea, he does like. The sums up, you know. Obviously leading the fight. Yeah I told you. That was the fight. I wanted I knew that was my path to a title. Win that fight at the title and if you remember I, beat Robbie lawler. I had already booked my flight you till versus Mazda I knew one of those guys would be. You know top five right? Till one! He was stated number two Mazda all one so i. think he moved, was he to three or four, so I had that foresight to know that was the case, and then I had to commit Georgia fight me because if you recall GonNa Fight Backstage Leon and he was Kinda hesitant because of our training sessions to to accept the fight. which you know, he's trying to rewrite history on that, but that's you can go through by instagram timeline. If you want to see the dates, you know there was the one where I had to calm. A naughty word, and that was I. think that was the one that set him off because he referenced at that one video several times in the future, so I knew I knew that was the one that really got to him and finally obviously he accepted, and I thought that was perfect for me. Obviously turn turn on ought to be perfect, but that that was where I wanted to be. No one wants this distinction but I. I have a hot take for you. Is it possible? Is it possible that that loss actually made you more? Popular is a possible that the way in which you handled that laws. A year later has actually turned you into the ultimate baby face. I think I. think that happened a little bit right, but then you the other side of the coin. If I if I win that fight I'm fighting. For a world title. I mean we're talking about I could have been probably the most popular to definitely top three. If I win the Mazatlan deadly top their most popular fighter in the, there's no doubt about that I mean I was probably at that time out, probably a definitely top ten, but you could probably even argue a top five when you look at the metrics on social media, if I win that fight. Fight I'm atop three for sure and then obviously if I was able to beat, who's men? I would have been you know top top one or two Radovan Connor in me, so I in some essences, yes, obviously is be more likable, and and that started thing, but at the same time. If I would've won that fight I, think I would have reached fairly high levels of stardom. Do, do, you miss active competition. Do you miss being training camp? You missed the feeling of having a big fight. You miss any of that There's aspects of. You're I don't try I. Don't really train I came. My hip is so bad. I don't really do anything I mean I have a hard time. Show moves at the resident Kademi. I'm getting my hip fixed number one. You know I. I kinda thought I didn't know. Krone was GONNA hit. Who knew that? So is GONNA. After the camps, these information for wrestling camp Ozzy residencies in rest spring season in camps in the summer I was GonNa do it after that because fall is relatively slow for us. I'm getting done September. yeah, obviously, there's things about it. I Miss I. Mean I was a high level competitive for say a good twenty our twenty years of my life, maybe somewhere in there I mean if without really high level, maybe maybe sixteen seventeen. And I would say I lean towards. I'm enjoying my downtime in retirement. more than I miss the miss it right if I miss it that much I'd probably I'd probably some desire to go back I. I don't really have any article. GO BACK I! Mean I feel I. Push Myself Hard for get close to a twenty year chocolate lab. I remember or the freshman high school at age fourteen inside I. I wanted to quit football because I want to focus fulltime on wrestling. And that was my start wrestling year round competing at national the basis that I didn't retire 'til it's thirty five, so not really kind of a twenty one year That's kind of a marathon by the way when you get the the hip replacement, kind of recovery. Is that like how long before you can move around and? The pain free life, so I'm doing that. I've been the Birmingham hip which is I. Guess is not a full full replacement, but it is a replacement. So they said I should be off crutches within two three weeks. I think something like that, but you know these are like full go. Full go which I was really happy because with a full hip replacement. There's a lot of things you're not supposed to do so like I. Really Miss just getting on the mat wrestling with the kids. You know some of our better kids right? I I've missed being able to hop in and give them a look or wrestle with them are pushed them over. I. Really Miss that. And so I'm really looking forward to being able to do that again. Which you know there's a full year before? I should go really hard but they said I should be kind of like only no normal within three or four months, but they really want you to do it right, and obviously if I'm getting a frigging piece, put my body I. Don't WanNa I. Don't WanNa. Do that wrong. So obviously one of the main reasons I wanted to talk to you because you are so connected to Maswadeh, and WHO's men I've got the chance to fight tomorrow, but you're you have see? Run was very much tight about those guys and actually WanNa start with something that you tweeted. I believe on Saturday morning once we found out that Gilbert. Burns was out of the fight due to his positive COVID, nineteen tests, and then we got the tweet from from Mazda. Got The tweet from Kobe Covington. You wrote. Does being serious to something the extent of Mazda all means that Kobe doesn't and it was obvious to me I mean maybe it's because of my relationship. Retirement woodland how many times I know. I, know for a fact oppor that in accepted I think six times against me and Colby has refused on the contract he at this point he trending towards the area of Keyboard Warrior, I know he actually is in a cage I know actually good at fighting, but when you. When you say, you'll do something, and you don't actually mean it just takes so much away and oddly one of the sticks. Colby kind of had going for him. was that he would just show up and fight right, and that was one of the things he had going for him. And now he's proven that to be false. I. Mean He volunteered Euro? You remember the being the krona thing he volunteered to fight. Would a couple times and everyone was four except Colby. He said he would do it and they didn't do it right and he's done a few of the time. Time, so we just know he's. He's being a poser at this point and again, that was a positive thing towards his character. Now it's actually kind of like will. Everyone knows you're fraud, so it's not a positive anymore. Are You surprised ultimately that okay? When I see about a two things I'm wondering your if you're surprised about number one. Are You surprised? That Moslem took the fight on six days. Notice okay. I followed this up with a tweet and I said the same thing. Kind I want to say it the no lose for George but it's damn near. He can't lose it, and so one of things was he got paid I. Don't know how much more he got paid. Obviously, that was why they put Gilbert. They didn't put Gilbert Burns in because that's a more enticing. They put Gilbert in. They put Gilbert Burns it. Because Dan is a frequent hard ass and he didn't WanNa, Pay George George wanted to pay it. was that simple right, so he says okay. We'll you someone else that and they did now when that someone else is taken out, and they really need a big fight. Opposite went called. Mazal, Vermont all my tape would be. More poor him to get paid what he's worth than to actually have a real training camp and on top of that I would say. Giller birth on got picked. What like four weeks ago could have been that long ago so prior to that Georgia's probably really training for the title fight, so if he did take any time off, it was a fairly minimal amount of time, right? He was probably training for the title. Fight Mitchell I love it. He probably He. Took a little bit time off, but not all that much is what I'm guessing. And So for him the fact he got paid what he wants is that's more important him, and then obviously if he wins great and night can keep keep demanding more money if you lose as he can. Then turn around listed I took this five six days known as GimMe Gimme a real title fight with a real training camp as long as it's relatively competitive that that will fly. Considering, all that Mazda said in that past month when they gave the fight. The burns right was very vocal about a lot of business related things. Are you surprised that the you have C. went to him? Are You surprised? They gave him this fight. No, they had to. And now I mean that was what he wanted right and before they had another that other option was Gilbert Burns. At this point you know there was I, guess you could say. Maybe Leon Edwards was option, but who knows if he was even training or or or anything like that Yes so I think he was their only option I needed a big fight, and that's why they went to. Okay, so I mean. Surely they've thought about the repercussions I mean even once. He got the fight right like he's on first take on Sports Center I'm Tom Osborne all the time? Yeah, he's continuing talking about the business and all that imagine if he wins. They've got out of potential issue. He has all power update. Yeah, there. That's a risk that they're willing to take. Apparently I mean business. There's no there's no cut and dried answers and business. There's always risk reward. What are we risking? And what are we? GonNa get and I saw. A can't remember the exact number you said, but I agree with you that the number is going to be a lot You and Daniel talked about how many more paper of uses in his cell. And you know no one was excited for burns. It was meant just work right, and that's kind of across the board. You can laugh, but you weren't and now. Now that it's been Mazda listened. To Social Media Lot right I'm not seeing advertisements of open up obscene, a lot of advertisements that George All annoyingly sell. I'm telling you. It's probably five to one. Five to one people are excited for George Mazda and they're not excited for I, it's really it's really that simple and they weren't excited for been burns at all use. Men's gotta be thrilled. Right I mean. Georgia's doing so much promotion for this everyone site like regardless of you think it's one hundred, thousand, two, hundred, thousand more. He's the champ getting points out. How much more did you say you thought it? Well I said five hundred thousand. Yeah, I mean that's a huge number. There's nothing going on, and everyone loves Mazda all right. Yeah, I unfortunately. Let me see. I would say five hundred thousand seems like a lot to me because it was a three title fight cards, so I was yeah I would've guessed. Let's say four thousand something prior with the three title fights, and then there's a couple of their decent fights on there. And, now I would say maybe seven, eight, hundred, zero, six out during the four thousand, which that Daniels. Both they're both reasonable guesses on what the truth is going to be yeah, I would have to assume who's been is going to be pumped and I I, don't know. Will it also depends on? How did how did WHO's men in Gilbert Burns? Go into together. Was it was it was in the bedroom? Did he not mean who's been knows I'm going to? To Be Gilbert Burns pretty easy. Then I think. Maybe there's an aspect where he's like wider Roy like this, but if Gilbert Burns is giving them hell and the practice room, and he thinks malls awesome, easier, easier fight. Maybe that way that's great for him isn't is better frozen though you go from the awkward situation of fighting a teammate or next teammate or Sure so guy that you despise way better to fight a guy you despise now. We'll get to practice room if you've mopping-up Gobert Burns then. Yeah, that's probably how he feels, but if Gilbert Burns was giving me a hard time, he knows this is. This is probably fifty fifty s. these kids and Elizabeth Belt then then yeah, these pumped about it, but if it's if it's a mop in this dude up. He's a bomb then. Yeah I think I think he'll be thrilled for change knowing who's been like. Do you think it annoys him that he's the champ and Muslims getting all the attention. Yes, irks him so bad. I guarantee it why. I mean you have to ask him for some deep seated? Reason why a you know and there's there's there's this some people that feel like they never get the credit and recognition. That is Irvine You know an MA will. We've talked about this area. You have to look at your personality and yet to see okay. What about my personality is perturbing? People are making people not and so if it goes far enough to perturb them where they really hate you and they want, see could beat up said Connor would be a great example this. That's the great thing right, but when the specter of they love you and they hate you. You don't want to be in the middle right and that's kind of ood probably is just like the middleware. They don't really like him, but they also don't really care that much and that's a really bad spot to be an and yes, I get I guaranteed that. Despite the fact he's GonNa paid a significant amount more He is probably very very annoyed and will care that chip on his shoulder. Let me, tell you about our good friends over at manscaping a new sponsor on the program. Of course they are another official sponsor of the UFC. So the he know if they wanNA talk to the UFC fans, they come to the Hawaii show, and of course these days we're at home. Go through a lot of our own manscaping. If you will, you're cutting yourself. You're looking like a mess well. Let me tell you something. MANSCAPING has redesigned the electric trimmer. The manscaping engineering team obsesses over technology developments to provide you the best tools for your grooming experience. And they spent eighteen months perfecting the greatest body hair trimmer ever created, and they just released the new improved lawnmower three point Oh. Third third-generation trimmer features a cutting edge, ceramic, laid and advanced skin technology to reduce manscaping accidents when I tell you this premium. I mean premium I. Don't throw around that work like it's nothing that means a lot. Premium means something, and this is premium better lasts up to ninety minutes. You can take longer shave. 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Actually Really Think I don't think he gets enough credit for his wrestling. When what was the fight where he's rattled a whole bunch? Well, you know, but I know. That's his bread and butter. Okay. I guess why I'm bringing this up. As I see a lot of people, saying is GonNa rag doll, just a completely dominate him I don't think that happens, do you? I think there's a possibility of it. I think I think there's a reasonable possibility of it. You know obviously my. It took him down hand full-time. The control them so I would say you know. My probably got worse. Than does bobby might as well. Wasn't that a different MAZDA? Although like he's changed dramatically since then I don't know I. Mean You know right? He is a Tilden Russell in all right? Didn't that didn't happen me obviating chance to wrestle him and then. was no wrestling. Right, so we haven't necessarily seen you know. I know Ozzy's put timing doesn't in any values that you know that's an important skill. So while I was going to say the Maya has great control right? It is control as outstanding Whereas maybe it was, isn't so I? Think maybe the bet is that he thinks maybe, but he can get up and you know for for a wrestler that there's. There's nothing more annoying when you go through the effort of putting someone something down, and then they get backup. That's so annoying. You're like damn. PUT US down. I got taken down again and obviously. If you have a lot of effort into the take down, it can be exhausting as well so three to one dog right now. Do you think that that's a a fair line or are you surprised at? It's that close. Yeah I mean under those odds I I would kind of lead Mas Vidal I I think I would I. would odds make I'm? GonNa make the odds. A little bit closer than three to one is fairly significant. I I think he's kind of overplaying his non training camp last. Think you've probably training thing using the fight and they would burdens dead, so I would guess he's at least in decent shape, if not good. So Do you feel like? He has to win the fight in the first two rounds. If it goes the distance, this is a no, no I. Don't y you know if he will. I, it's okay, here's a here's the thing with and I think some people underrate this. They'd think as wrestler's wrestling people. It's hard right, so you're generally going to get tired throwing punches actually not that physically taxing i. I wish I could remember a fight like this. Just a pointed out, but sometimes wrestlers get tired and when resume tired and striker still have a little bit of gas left. You know may maybe like McGregor. Mendez, where you know as work pretty hard to keep him down, you can tell when they got up the second novice that was short notice. Maybe you'd make that as excuse, but wrestling people can get exhausting. Fifteen twenty minutes, and then the fighter that good striker, really only asked land a few really hard punches to put someone down, and so if you can make the wrestler get tired through wrestling, and getting up and stuffing, take downs, and then you can get them to a point where they were. They're pretty tired from trying to Russell you and you dilan good strikes that can be very beneficial to the striker. Why? I saw yesterday I think it was yesterday you tweeted. Mardi sucks just out of nowhere like what prompts you to do that? Its social media. Thaw came to my head. Or, maybe I saw that old clip of us. I thought about I saw somehow social old clip where they got in a fight at the Super Bowl Yep and I'm just like This dude socks and I'm like you know what maybe other people laugh at that thought, and so I just went twitter I said Marty sucks. You didn't you didn't think it was endearing when he kept repeating. Do something. So annoying, it was it was the same thing when he when he when I said it must've next Marty and I knew that would. That would irritate him so bad, and he rolled of like okay dude I know you're tough. You're fighter like we fight in cages. Does what we do like? Why do you gotTa Act like a Poser Exa. Tough here in the hallway, because I know you're not gonNA. Do Anything I'm sitting here with flip flops saw leading my ass against the wall. Because you ain't GonNa, Punch me, you're not. You're not going to risk losing a title. Fight or losing opportunity are getting fined because you punch me backstage because you're that upset you just not going to do is to stop faking it. You're faking it like stop. Have you ever had a private conversation where you guys tried to clear? The air spoiled by your different even after your retirement why I know I. have no interaction with him on a personal level, so I don't see. If I had to work with them or something, I would try to clear the air but I. don't have to work with them in any way shape or form, and so no, I will I have no interest in that. These told me back in the day. He remembers him at the Olympic Training Center in Colorado. Did you have interactions with like? Yes, that's why I know the whole thing, but like where you cool, that's. This is the whole contention I have errol. He would just a normal cool dude like hey, the libertarians are will stay the dorms all hang out. You pass each other I. Mean you're the same practice everyday you'll eat in the same dining hall. There's there's only two lobbies in the dorms like everyone is very interactive. Right and so there's no time you can't act like a poser and act a hard there because people eat you up. You know I mean they were just make funny. They would tease you and. So then he goes to Emma May, and he also has his persona that he's the hardest dude ever, and he's so cool, and it's like that's. It's fake and here's what everyone sees that. It's faked. That's why can't bands because we know it's fraudulent. It's not real, and that's why. I was so annoyed and that's why says like that's not the do that. You were like you came them a May and you thought you had to beat this other person, but people are seeing through. It's like when John Jones tried goody two shoes like. You. Know people really start. Liking. John Jones when he's top lawyer. Good to show because we thought they were. We're going to John Jones now well, you know what the Real John Jones. He is a perfect night us. You know what we love that. We loved the Real John Jones. He's a real dude. He makes mistakes. He says the main things you know. He's a little bit arrogant. Will you know what he was? The youngest champion ever? He probably should be a little bit arrogant. We liked that so when we saw the real John Jones, we said we embraced it. We sent we love. People Don't pee. Sometimes. You can't even explain to you and obviously people. Most fans don't have this personal interaction that I. do with WHO's been where I know. that. He's really not acting real. And, but they could feel it right just like feel John Jones and so those are the two that like people. The love DC DC's my boy I was so annoyed with John Jones Aggregate Asfaw to DC and people were doing DC. They see. Our. You're going to boot. He's like the nicest guy ever and John Chosen, and they loved it. They love John Jones being real and people. People don't like fraudulence. They love it when people are authentic and so they were booing keys because they love me, not because they hit these people because they love John Jones and it was fantastic. Entertained a watch. Do! You feel like that's why people love Mazal so much I. Mean obviously the fighting last year were great, but like showing up in the robe, and the beard and the hair and all that. Why do you think there's such an I mean? This guy has been you. Don't see in sports period. Not just you don't see a guy come into his own as a personality, seventeen years into his career usually yeah. I put the spotlight on them. You. But. It is right I mean his wear falls into. It went fightbacks i. put the spotlight on him. I played the foil to him. I let him shine. Unfortunately. I was GONNA crush him, but you know he a says some of these things like the three piece in a soda that are like. Maybe he's not intentionally funny, but again it's really authentic. The people love that you know when he said F ING Super Necessary which I feel like he's. Punching me when I was already unconscious, that was just unnecessary. But. He said it was super necessary like you know what it's pretty funny. Punch and you say listen. That was George. Being real was kind of funny. Even though was being. I thought he's Douchebag for punching me after I was unconscious. It was kind of funny, so yes, there is a certain authenticity to George that that people really really enjoy that and listen think about the people who are really popular. They're very authentic. And when they start getting faked, they start they start their demise I mean the one I think Ronda was really authentic in the beginning I thought she started having Prima Donna think tour at people. freaking hated it. That interaction that the ESPN Emma May instagram account highlighted between you in a fan of the five seconds, and all that you get that especially now. Do you get a lot of trolls who try to make fun of you about this I smash them? Would that mean? Put them all in their place listening. So. Here's what I do with. Grab my phone. Hey, remember, grab my phone I told you I thought. Dylan. Actually? Such a deep shit. Here's idea I'll go right up, so go to mansions. To See if there's anyone important. And then I go to. Go all magic and I scroll right and scroll at every once in a while. Stop on something that'd be some shit, says something, and then I'll hammer smashed. You know it's like due. To religion went for the. Dogo moves at all. You know like you shouldn't have done that. It's like Oh okay. Does it take a? Genius to figure that one out on. So, give us the funky breakdown. How does the fight actually play out? Yeah I'm interesting 'cause I you know is part of me. That actually says who's men is able to take him down and control him for a long time. But Hey. You know what I talked about where wrestling gets tired. You know what the perfect example that is. Why didn't think? My my muzzle, my guitar throughout him muzzle very clearly when that the route designate example? My was able to take him down the first you route, but eh did was. Exhausted but was worn down from taking down and had a very tough around. Any clue lost at the round. So you know there's partner says maybe it was making. Take him down for five hours down, and as part of minutes as. George either stuff some of the take downs, and and or gets tired from trying to take him down in the latter rounds is not able to do so and I you know I, think if it's just striking battle battle I think I think it's pretty obvious that George wins that one so. I would probably lean towards. I would probably lean towards these men for sure but. I thought you were going with your boy. I think there's distinct possibilities where Mazda win. Okay, so the official pick is. He'd saying it pains me to say yes. I think who's GonNa win, and that's so annoying decision. I would say I have a hard time seeing who's been finishing Moslo I think that's that's relatively unlikely. Do you go back to Burns after that or do you do? Take them in a different direction to get who you gotta go back to burn. I mean well get again, so if this on Edwards. Poor guy people forgot about him. This is despite his competitive. This fight is competitive and Mas Loses Mazda. We'll get a rematch. Interesting over the full camp, interesting the full camp. Yes, they'll run an angle. 'cause. It's going to do good numbers. You and I both the greatest numbers you'll see wants to do good numbers against Gilligan's will not do good numbers and if it's really very uncompetitive and boring like Mozelle takedown, not able to get up there I was gonna give the rematch, but it's competitive. Right if it's forty forty seven, if it's really competitive, bright bright moments for George. They're going to give him a rematch. If Maswadeh wins, you do D- as to for the belt. I mean I. Don't I think that's dumb? But I think there's a really distinct possibility of does that the other the other thing that you other things. MCGREGOR'S GONNA move up in fight fighting. And that will be a gigantic fight, so because my McGregor obviously third title who's been will be a terrible matchup. McGregor in my opinion, That's that fight was was not made by MAS at all. McGregor it'll be McGregor, Mazda off Moskowitz okay so the official pick is WHO's Mon-. Just curious before I let you go. Volkov's Holloway just give me a name. You don't go. Vulcanology I think he won fairly clear the last time I you know I. Don't know that Max is GonNa make enough improvements this time to make difficult yon although. I think yawn. He's been really impressive obvious party it says Jose Aldo could still win, and both of them are really fast in both hit really hard, so that that you know that kind of always leads me to say you know. Both guys have a really good opportunity. yummy unison on drudge. TA, Rose Rose, but tough one and does page is an cash in her last. This is a fine. You're no revisited savage. Mackenzie she's. Kind of a bad ass, so you think she goes into free agency. Awful loss loses all her leverage. Yeah! By the way that was cool of you to give the fighter some. Advice on taxes after the Mike Perry stuff out. Alvarez! I think that are really good thing about well, then I. I actually did a podcast with the guy who owns a CPA for okay I. It's up for free on rock and we can watch and we talked about. Some of the misconceptions on write offs on L. C.'s on all those things you know kind of just giving giving fire to perspective on what they should do. Yes, these fighters are clueless. The VOC has nothing to help. Most managers do nothing to help, so you left on your own to educate yourself and obviously doesn't turn out welfare everybody. Last thing. Why did you change your name on twitter almost every day? Like now it's troll. Smash Birthday like well. Why? Why go through the trouble of that every single? You know what I got I got bored during quarantine. 'cause there was I. don't know what three three months where we had no awa going on and Yo- there was probably two months where were amazed at home for three weeks did not leave my house but there was probably two hundred where it was leading relatively infrequently weeks I'm going on four months of leaving my house. Live near city. So? Yeah, of course, Qatar Air with. God's people don't give a damn right now, said my wife and I won't social gathering at my Buddy's house Oh. It was five families. All families were close with, but do we're going back, errol. There is a country Western concert going on, we're like holy I mean they're twenty hundred people there and the budget. All people live. What is going on? They literally don't care about you know. The kids are going up and so I guess they're not seeing. They're not seeing the effects of bitter or something I listen people, Wisconsin, they don't really care people out everywhere The lake was packed on the fourth of July. The beaches are packed every day I. GO OUT! It's it's. It's wild here, but yeah, so anyway. I got bordering Corinthian start changing people entertain people as now I. Don't do it every day by. A couple times a week. Whatever's mind well. You are very busy man. You got a lot going on crazy. What has happened over the past year? Get to catch up with you on the anniversary of one of our more famous interviews in the history of the show I. Appreciate You doing this. Ben Aspirin and on Saturday Masuda watching. Yes, I'll be EMINEM's people over like you're. You're not invited though, but we want to be invited. Are you kidding me I? Want to stop? You're not scared I'm. Pretty scared out of you. Are I'm very weak. Human being I don't know if you know what I'm very scared. Thank you bill average it? Ben Aspirin like I said always money great. Catch up with them exactly one year after that. Infamous interview on the program. Great stuff from him always love hearing from his takes great whether you agree or not. He's entertaining and When I found out that use Mazda dollar fighting I thought all right, we gotta get screen back on the show, and I'm glad that he accepted so matter of seconds. We're going to be joined by Henry. Hook very interested to hear his take on the whole Burns whose Ma newsmen changing camp situation but I. All right. Let's take a brief timeout here. This is great stuff with Ben Aspirin, but I gotTa tell you by my good friends over at Modell modell Oh aspects. Ya'll food for those with the fighting spirit, modell's the official beer of the ultimate fighting championship, and is brewed for those with the fighting spirit. What is the fighting spirit? It means never giving up people when the odds are against you. Do great fighters. We'll see on Saturday. Did it did it. Veers? It doesn't matter where you've come from. It matters what you're made of modell's than the gold standard. Since one thousand, nine, hundred thousand five modell is Chris Pills nurse style lager that set the standard for authentic. Mexican beer modell uses premium hops to give the golden lager. So. When you're watching, C. Two fifty, one on Saturday on ESPN plus pay per view or any UFC card coming up. In this month of July, make sure you've got the beer. That's always in your corner modahl-less best. Route for those with the fighting spirit through spots be imported, but. Now back to my conversation with Funky Ben Aspirin. All right now, here's my conversation with Henry host. It's been a very busy time for you and the team, and so I appreciate you giving us some time here today. obviously one of the big stories this week. You have C to fifty one tomorrow Zeman, fighting once again defending his title was supposed to be spun versus Gilbert Burns. Now has been versus where he well as you know and when it was spun versus Gilbert Burns. You are A. A major part of that story because Camara who spend has been training with you for years now you were his main striking coach years. You were by his side as he was coming up. And when you won the title of course, and of course you have molded Gilbert. Burns, it's one of the best fighters in the UFC as well so this became a really interesting story than we found out that. A move to Colorado to train with Trevor Wittman and It was going to be this you know, friend, colleague versus colleague, teammate versus teammate story, but now it's obviously not turning out. That way still wanted to talk to you about it all so I let me ask you. If this was never booked was always going to leave Sanford MMA or did he leave according to what you know just because he didn't want to train in the same places Gilbert Burns. Yeah no I think could give us. A smile will is is part of our team? When I spoke him he said the Florida's always be my home base in the. He went trade he he always when he beckoned Dallas with suddenly always POPs up in gym. He's been so couple of. James also worked with Trevor and service, or is very good goats. A trevor makes. All my my mic commitment, so I have a contact with trevor and the we talked about it, too, and so I think Florida, it will be his home base in the. He's one of the members for as long as I. Know All the guys that art gym. Respect them the same way. I don't think anything's changed. I, I read on an industry that the somebody if that. He said that he wanted some extra attention, I, think like I said before I. Don't WanNa. Get into too much drama because there really isn't a foamy. He's my team member one of my students. He's my world champion. He changed my life the way I changed his life than We'll see after this five even when when the when you left Gherardo I really didn't drink with. Everybody knows that will best for him. Everybody else's working because I I still considered in both these guys my students, so it was a it was a difficult time. Know and the I. Don't know I don't I don't think. Kamara would have left for the whole camp maybe for a couple of weeks. and. I don't I don't think that's something that's bad for some students also see what's dad other words without people. You? Keep your relationship real, and and also when you. To the right people. That's not really a problem because if he would go somebody that I thought like. I don't know why you go that. Then I probably had a discussion, and if you wanted to leave, I would say to you know, but it wasn't being. Trevor have contact even when he hosted five Gilbert as. I was heartbroken. Because my guys, it's bittersweet. Travel he we talking he. He. He made me feel like. Yeah, it's two of your guys. You have to be proud of that that they came there, you know. That old growth to be like that so. Phases in my gym. Sodas are in my gym. Is posted in my Jamia so much feminine, My Jim Rob that falling apart office bed. Skies guys any. Need to keep that shit away from me, but yeah, so hopefully you'll be back. We will see but I. He has a big fight than the I. Just texted him by the way. How he feels so messing. Yet because I can't imagine as a coach. You know here. You have a situation where you have to guys who you helped groom. You are a massive part of their maturation as fighter, and obviously the champ and Gilbert having this incredible year. He Beats Tired Woodley when he beats woodley. The mix of emotions must have been really incredible for you right. Like what were you feeling inside? Because at that point, you must have known my gosh this. This might be inevitable. I might have a real problem here. What were you thinking then? Yeah, you have and that that's that's That's what Dick Amaru also said. We have incentive Lukic give up. Burns markle's. Mon- Daniel Roberts still far away. But these there we have a a cup of radical on seventy guys. awesome ballots over in Europe. So, there was always we've talked about before. We Talk I. One the boil ships going on the. Fight. So so you always have to figure that out. It's very hard. Fault have so many good fighters like I said before we have around seventy people in the AFC. Just a lot of people. And the competition show high again so much feet of each other. They get so much better that one day they will fight each other and the. S trainer. It's of course very hard, but that's why I said to you. That's why I didn't WanNa do any interviews? It anybody because I don't WanNa be a The main role is to guys are the main role that they did it. Of course be held up. I don't WanNA choose any, sites And just don't WanNa do that because. I would just let them fight each other, and nowadays without the audience is, it's more of a sparring match. It could have done it even here in Florida indicates. Cameras on it and you see these guys spot as far like they're fighting like it's really true. My are sparring really hard. They go hard and this probably part of our success. so Yeah I know mixed feelings, but again like I said it's all about these two guys, and now just the sack. We hear that the one guy stream stake in win. but I'm happy of course Malkin show Saturday. Wise Chiampou. Once Kamara decided to go to Colorado and obviously you're at the gym and you played a big part in Hilbert's rise. Why didn't you work with Gilbert? Well, I think and again because. I if you have a problem with the fighter or your bat therms, I can understand it but I. don't think it's fair. If you've been be so long to with each other loyal, if to understand, these are fighters being the tuning in the gym. My Wife's Day Scott Shoot. It's like we have a very good pilot, so it's not just. It's just very hard to be in the middle. And I did the three three weeks guided molest bet session with the spun. On a day when in BAFTA incubus garage and the rest training Jim, but I didn't give him any advice over because at the end of the day. These guys know. fight each and I never been in this position before this level that I had to have this around the gym, but It was a good decision to go over there. He had his Cambo for. This thing over here all students that trade with Cuba train also with tomorrow, and there's nobody saying Left airs reading or it's is not good. They fight each other every day. They know exactly what they're going to do. So that was intriguing part of it and I think for me. It's better to step out of it and not. They excited again because if you stand in somebody's GonNa. Against, the other guy and I'm not against the other guy because guys might champion. It's hard. Yeah some people ask me also like okay. You can just go sit in the audience I. Just enjoyed two of your, but he's not a I probably wouldn't even look at the site not because. I'm scared, but I just like Let them figure it out, and then we will see at the the next day. Emma Junkie or something. What's happened, so? That's easy as it looks. Once. Gilbert was forced to pull out of the fight. was there any talk of you cornering tomorrow? Now I think also first of all, the timeframe was really weird because I was in Vegas. With the. One of my Japanese guys. In the great five in a stated they, longer, VEGAS Because I'm supposed to drink, but anyway Sean thing I stayed there longer Japanese French and everything, and then some stuff happened. And I went back on Monday night and then. she was leaving the next day. In advance so fast that it was already halfway up, everything came about and then. There was no thought of me and. I don't know if there was a thought Kamara side, but he was already on his way data to come back to Florida to pick up his daughter and be with his daughter, so the timeframe was so weird and everything and an air already has his people way trained for three and a half weeks. Driver is brought as always in the corner. IAGO is with me always at every five. So again we text it, you know. He went back to Vegas went so fast now. Dan even prepared so no, it's good like this has come. Told you that wants. This fight is over. He's coming back to the JIM. Yeah? Okay, but he's happens now. Because it's it's Mazda, alright, so there's a very good chance that he wins this fight. Go back to go right. They're going to do the Gilbert. Now, Like, we said before we little. Sit Down with each charter Coaches and he said I'm going to do my dad. He said, but I'm I'm going to be back here. This is this is my home base. You know so well. Whatever happens, I'm just going to do that for now. We all read up on it so. I. Think that's still the same thing still. He's finished to come back to pick up his post. But yeah, if you will find Gilbert again that we have the same situation, and the and we do the exact same I will do exactly the same. I will stay out of it. I was out of the out of everything because again there two of my guys, but like I said to you before. Crazy man I have three people in elevators weekend. We got like Bella tour UFC once once one. She's GonNa pick up. At. Around thirty five I level fighters here. We have three coaches so. It's it's a hard working does where I'm so happy that we. That we partner up with Sanford the infidels, so our budget is going up a little bit. We got a brand new facility and these people are give US A. The opportunity to to get bigger staff and. I WANNA to do a lot of stuff developmental team. I WANNA. I WanNa ten this thing into nfl kind of MBA kind of program. You know that's that's next next task related. I. Want to read you a quote that Camara. Gave my colleague Greg Okamoto. Ideas, Peon, he said quote I think eventually I would've changed things up anyway. We had a lot of welterweight at the gym at some point. When you're training with these guys on a daily basis in your champion of the world, these guys know you in and out, and if they get the better of you one day, they're licking their chops thinking. It's their time a little separation from that as good. It keeps that element of surprise because these guys feel like they know you. What do you make of that? Do you agree that eventually? He would have had the chance things up. Yeah I think so I think you make the right decision. And again it's everything goes at respect, and that's some both sides for short with me and my fighters. Is Is Yeah I. Understand that, don't they? Understand it then also. He understands are we talked about? He understands also the coaches. Feelings because we can't just train one guy. Of course we do separate trainings with guys but I, think the strength of our team is that these guys all trained together at some certain days and do things together and. It's it's only It's only a good good sign. A few of you guys work if you if all these guys getting to the next level and the and that's why it's dudes like. A lot of people do you can check out? Did he went somewhere for another? Kemp is good to go somewhere else and be around other people and see. What's the difference especially at that? Level especially at this point of his career, there's a lot of young hungry upcoming fighters, and it does the understand it. You know so yeah. There's nothing wrong with that quote. Understand what he means. Is. Is there any part of you? That worried a little bit. He goes over there and he really likes it and doesn't come back. No not really because first of all. I think where he trains. Trevor again. Is a really really good coach. Okay, we have a good relationship. I really like Trevor, so I don't think. There's any worrying for me because again. I already built that house together with him. That's the way I call it. I built the house. If there will be another trainer yet, I will see that as somebody who was Nice, curtains in the Sofa but the? How was already already built? We challenge each other's lives if it starts here if it stops share and I I. Don't think we'll stop here again. Florida's homebase. Yes. I think. I think we did a great thing you know and No, it's it all goes when you do with respect and understand standing and I was fighter before I to a couple of gyms, but I did my last couple of Pfizer by I coach. So Respect. Nothing is really wrong. There's always door's always open again when you wanNA, come back. You know your teammates are open for the respect is the most important thing that you need and again you cannot stop people. WanNa learn simple somewhere else is good for them to see how it is somewhere else, so no, it's good. House Gilbert feeling. Is Good, he's good. The at some had some headaches. That's the only thing that he really had with this thing. A lot of people have those no symptoms. Serbia scary thing but. Now yet something he has some headaches and. He's good these relaxing with the family. He's been training in fighting in March may so. he fought a lot, so he's been shooting a relaxing. retested next week. I when he's clear to to come back going to out because we got again like I, said gotTa Logos Stoli's finding Baladora soon. We got a couple of guys. The that the we need help with, and that's a good thing about guys everybody after the five. Sato is going to be back. These guys are going to be back because. Within the AFC and in Ama- May world. You gotTA call. You can fight to reach. I'm not truly opportunities there. You cannot say I need to eight week training camp. Miss a good thing about. Those are. Always in the gym. Was it those ready to go? So that's a good thing that they could great. You'll be. Any concerns obviously as one of the head coaches at Sanford about trying to keep the healthy because you know obviously what happened to Gilbert was very unfortunate. I know online saying tested positive as well. You know these geyser. It's impossible to not be around each other right, and you're sweating and all this stuff, any concerns about an you're in Florida and unfortunately hasn't been very good in Florida. Are you concerned about that about keeping the guys healthy and not? An outbreak to happen at the gym. Yeah, no for sure but we. Always very worried about certain starbucks. The guys at a training now for the Pfizer are already tested like they're already tested because now. They're smart enough to okay. We need to get the best it sooner than later. Because if you your loser paycheck, so we split up. We have two locations so the people that are really really have most symptoms and haven't been tested. Tested they've train at the first location and the role goods, and the guys that are fights coming up their trying only people that are already tested, so we tried to do as much as possible, but like again we had one house where we're. Four fighters were to a negative through a bus. One get retested was negative and he got tested positive after it's like. It's so weird. You know. Try difficult to handle, but again the guys Jason Jackson met medicine betray on these guys. They trained with the guys that already tested been there already good, so we tried to do the best. We can so. What is it going to be like for you on Saturday? We'll you even watch the fight. There's your student, a guy who you helped become UFC champion. I believe your first USC champion right when he beat. Tire Woodley and you're at home and he's fighting his bitter rival Maggio such a big fight. What is that going to be like for you? And Will you even watch it? Yeah. I'm GonNa Watch this one because Different scores. And I want. Of course I'M GONNA. Just support him. I said last week. I sent him a little message. About fight about. must who I really respect because I really like people like that. They just come to fight you. Of those sometimes, the talking bit too much may not at the only mustered love everybody I? Know it's now part of game every like muscled also send him a message what I think We had a little conversation about it but I. I'm very intrigued about this fight because I wanna see. Again. It's been eight years. Training this guy on the rest of this. Stand up to I think it's GonNa, be really intriguing to see if if he does what he does, normally maybe at something. I don't know but. and. It's also intriguing to see how much Fights this fight because as just as A. Pure From the outside looking guy, it's a real match up, you know. again because I like to see must be, they'll fight every fight and I was. When is my guy intriguing fight, but like I said before, if traits the way, he always so focused, and he thinks the steps better by. Betty gets better. Guy To be. Very difficult to be anybody so. It's GONNA be interesting. would. You have watched it if it was burns versus man. No. Just really I wouldn't I wouldn't just watch it again I. Just sit here. My God way to the fight is over and then just. Era that she backed. Really interesting then at that moment because I just want them, both them both is dreams become champion, and the person is the champion, so it's It's just hard. You know it's big exciting kickboxing. I never really had to. We had like the K. Wanda Feeder and no anestachio. L. Fought each other, but was different. This is just the I don't know because. Yes gabe us from the beginning, and then really from the beginning. So that's a long diamond known. Business and I always say I'm not just the. I'm a tray number. Eight Breslin with to said the kids come here. We go to their homes. People you know so it's. I was thinking of you when when he unfortunately had to pull out of the fight. Because at that point, you got all the way up to a week before the fight. Okay this. You this uncomfortable situation is going to come to an end and he's out and now you're gonNA have to go through this, if Williams, all over again, so I was wondering like you're probably sad for Gilbert, but also Oh, my gosh, now. This is going to be delayed, so we're going to have to. You know because it was about to end at some point, right? They were going to fight and you would have to move on. So how did you feel when you heard the news? Like you describe it. In between like okay, okay, not gonNA fight each other. But I'm like okay, then they're gonNA fight. Each Other and there's GonNa fight much dog if he wins that fight still going to give. What are we going back to the same stuff again? You know it's but again is in inevitable it. Again, fitchet the fights to three. Pfizer you have three devastating knockouts you so close to it's. It's just like switch no I duNno, it's one seventy guys are also like. I come out played a big part of it. You make a lot of these seventy guy so much better because his resting also striking and and Cuba with Ajay and and all that mixture. Holy fighters around them that feed off of that and it got so much better that got a pool of people like I said six seven. About maybe ten people on Seventy Jason Jackson Logan Story guys all so close so good. That's hard. Again it's luxury position where you have all these fighters and your Jim and you're you really want to? Train your team to become one of the best teams in world and one of the best sizeable, but. You never really predict that they're gonNA fight each other. We always thought like okay coupons at once five dollars, but you need to go on Saturday and he will tell you that from the start. I will never WANNA. Dance fifty five because you've got so much way. But that's only. Is GonNa? Be Copy and the next guy person come by the. Extent say a couple more years so. Loose Mazda since you're not involved, can you tell us how you think it's going to go down? I'm always bought the when his answers that was can look in the future. Bob Obama ever like I said before I'm a big fan of must've really. Great Guy a really every time he fights I tune even if I have to pay for it because he's exciting fighting style of fighting. Everything around. But I still think that one seventy. Seven everybody can give everybody at one seventy if he trains right and he's focused very difficult to beat the Maru's word. He took the right steps to become the champion. Heels taste right steps in training. of course I didn't see all of it now, but I assume he does exactly the same thing. He's very focused. So I think you will win the fights and he stayed champion. And you will find brands. But in animate everything possible. No, it's like. That's why nobody wants to see it. It's different than boxing it's. Just different, so, but I go from our Guy Champlin Thank you for the time Henry I appreciate it as always wish you guys the whole team coming up this month with all those fights the very best. Much, Reo, thank you for talking to me. Really appreciate Henry coming on the show I had been bothering him for quite some time to talk about this whole situation, and he finally said yes, perhaps helped that Burns was out of the fight, but this could be an issue if someone wins on. Saturday, they're going to probably run that one back with Burns and he's going to be finding himself in the same situation I'm really curious. Curious to see if it was meant goes to Colorado really likes it there. Because that's a great team, whichever Wittman and just doesn't come back, that could happen. It has happened before, and it could certainly happen here but again like I said to him. It is a testament to what he has built with that team. to have two guys were fighting for a bolt in the. There's no greater compliment in my opinion to coach. Of course It's an uncomfortable situation, but I'm sure he takes pride in that as well all right now time for everyone's favourite segment of the week. It is time. For tst's minimum tip of the week, and of course it is presented by our good friends over at Modell modahl-less Speciale, sending the gold standard for authentic Mexican beer since nineteen twenty five modell root for those with a fighting spirit. Tease minimalist tip of the week. Aerial I wanted to wish you a happy birthday and to let you know that I got you nothing. Veteran listen I don't WanNa get you anything, but I do have a great minimalist tip, and I think this is one that you will get a lot of enjoyment. Adults I know you have an iphone. Many of us have an iphone, and if you ever want to delete a contact, a phone contact from your address book, it is very difficult. It is way more complicated than it needs to be. So I discovered a great. Great APP called contact cleaner because as a minimalist I liked to get rid of context. People I haven't spoken to in a while. I use contact interviewing CEO. I had four hundred something context I paired it down to about one hundred fifty people that I actually talked to or may get a text message from the near future or a got one recently so I. If you who I would imagine has a lot of contacts. Thousands of context of people that you don't talk to anyone. I was just going to contact cleaner downloading it. With their phone and basically just run through a checklist check. That person is deleted from your context there you go well first off I appreciate the good wishes. I appreciate the fact that you gave me nothing because out. Expect nothing less from you you know. This is a microcosm for the way live. I. Don't like to throw anything out including paper scraps. You know giveaway old stuff, so I do agree with you that I have way too many contacts and I will never get rid of any of them because my thinking is well in five years. I may need this person who knows. Why would I get rid? Rid of them now I worked hard to get that contact. It's not really clogging up my phone. It's not taking up more space taking up more memory or anything of that nature, so what we need to lead it the there's there's more bad that comes from deleting it than keeping it in my opinion, so this one I say thanks, but no thanks. It's the mental quarter. Maybe bothers me more than bothers you Coz I. Mean I it does bother you because everything seems to bother you. The fact that this doesn't bother. You bothers me okay by this. All right well, we appreciate the tip nonetheless, and we'll be hearing more from tst. This Friday my friends. Because how Lonnie Island is the real deal. You've got a live area. Hawaii's Emma may show going down Friday July. Tenth at eight PM Eastern, our first ever live virtual event. You know we've done the roadshows right now. We did the the Hawaii knows trivia challenge while that stuff will this time? It's going to be a great time It's myself TST A York Rick will be there. DC You heard him on the program on Monday say that he will be there as well and you guys can be there, too. And I've heard that we've got. Hundreds of people already signed up and more can sign up as well. There's no limit, so let's break this thing. Let's get four thousand people there. There it's going to be great. We'll get to fifty one answer some questions, so you can submit your questions right now. All you have to do to sign up is to bit dot lead. That's B.. I, T., dot, l., y., forward, Slash Hawaii Island, one word H. E. L. Wfan I island all lower case to register today. That's all you have to do bit thought Lee Forward Slash Hawaii Island and. July tenth at eight PM Eastern, and then on July eleven, the day of you have c two fifty one. I'm back with another show. How about you can't get rid of me? Baby I'm going to be everywhere on Saturday. Two to five PM. Eastern on ESPN RADIO ESPN APP siriusxm channel, eighty iheartradio APP smart speaker anywhere radio can be heard. It's the Hawaii. Show back on the airwaves getting you. You set once and for all for UFC. Two fifty one account for that for now we're at a time. Thanks so much for listening downloading subscribing rating reviewing, thank you for the support for the Monday show with DC Avi back on Friday for the virtual event on Saturday for the radio show, and then on Monday to talk to my man Daniel, cormier about the madness that is to calm on. Island enjoy my friends. I'll talk to you so. Did you know GEICO's now offering an extra fifteen percent credit on car and motorcycle policies. 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Aspirin Advice Reversed, Yoga Benefits for Heart Health w/ Star, Jay Hunter - Black Hollywood Live's Fit Club

Fit Club

26:26 min | 2 years ago

Aspirin Advice Reversed, Yoga Benefits for Heart Health w/ Star, Jay Hunter - Black Hollywood Live's Fit Club

"Welcome black Hollywood live fans onto date club. We talked the new aspirin warning junk foods fresh his victims and more with loving you drunk star. Jay hunter, stay tuned. You're tuned into black Hollywood live, the world's first digital broadcast network, devoted entirely to urban entertainment and pop culture. Tune in right now. Welcome fit clubbers. We are back. We took a week off of we are back with if loving you is wrong, sir. Mr. j hunter to glad you joined us. Thank you for having me amazing break premiere last night. So we have a lot to talk about again. My great co-host. I'm your host soccer Smith, and I'm doing my lovely co host mystique Trindad, we're gonna find a mystique online by me on everything at TK trade ad Mr. hunter, we're going to find you. I am j hunter. So. All right. We got it. Stories to go over I'm digging a little bit more about what's going on with you. But the first story was so interesting because now they're saying that you should not be taking daily low dose aspirin to reduce your risk for heart attack and stroke with completely floored me because this is something I've heard I was a little was just what you do when you turn a certain to take daily low dose aspirin, and they're saying that Bessemer some money and at worst, they may cause internal bleeding and damaging. So this is kind of crazy and they're saying, they're basically better treating the risk factors, hypertension, diabetes, high cholesterol. So there's no need to kind of use aspirin to treat anything. Right. So, you know, just hearing that makes me so curious when you're as someone into fitness when you're dealing with all these different things that come out this caveat. So what we should be taking not taking how do you deal with it for yourself? How do you govern? It sounds right. But is not working for me, everything that they tell you. I just put it inside. And wait five years from now. Because it seems like that's the thing changes every five years. Yeah. So yeah, they always tell us to do certain things. And you know, you gotta take it with a grain of salt. I mean, obviously, these people are studying doing research, which is always new things coming out for me kind of. I'm really into my body. So I kind of like kind of just listen to my buddies telling me, I know sounds weird doesn't actually talk to me like my wake up in the morning. I feel funny of them having you know, my head's not feeling right or from sluggish or, you know, not my sleep hours are good. But I I don't have the energy that I've been having. Then obviously, I'm gonna look at. Okay. What am I doing? What am I eating? That's different. Oh, yeah. You know, what I read this article told me to eat X amount of this. I don't think that's working for me. Go back to what I was doing before. Yeah. I think too many of us are just like we we just get used to the ills of the body and not even attributed wait input output, something taking in is causing this. Yeah. We definitely don't look at that. Like, I remember when we had the time change. I think the Monday, I was just my body was just like off. And I'm like, wait what's going on? Am I and I'm trying to break it down. And I totally forgot about the time change because now our phones do it all by itself. So you just wake up, and she said, I was just your body's not on that, you know, on the phone type clock. So then it's like, okay. That's why. So then I was able to. Okay. This is the reason why and then it made sense versus like, okay. I need to grab something to make my body feel better. So it's one of those things with the aspirin to it's I know when I was injured they had me on the eight million eight hundred milligrams, and I knew tore out the lining. So the having been a small Yoshizawa on a regular basis for a number of years. Can't be that good. So yeah, they're seeing you do good for people with high risk factors like if you've had open heart surgery, if you've had stents if you've already had a heart attack. But. For the average older American do not take those aspirin. But I'll just start because of you know, just kind of flew in the face of so many years of what they've been saying. Yeah. Yeah. She just eat could food and workout. Well, you know, I it's really about the mind body connection. Kind of what you were saying. And now this new Harvard heart little came out that said yoga's really good for enhancing heart health, because it actually attacked the same sort of precursors to to Heikal high cholesterol, hypertension, diabetes, and they're saying really actually works on the arrest and digest response versus your stress responses flight versus fight. And so you'll go and meditation kind of really worked to reduce some of this. And so did you find anything in your career that helped alternatively with with getting prepared for whether it was rolled for football. You know, I never really got a chance to indulge in yoga still probably should still. But so yet, you know, one thing that I've noticed. Yeah. Playing football as various very high on tensely, so your stress level. Does go up just because your body's like, boom, boom all the time. And sometimes it's good to still get the blood flow. But doing it in a relaxing way. I know it sounds weird. But there are things that you can do like for me. I will do a lot of exercises that are deal with high some metrics. So it was kind of like some simple as let's say I'm doing a squad. Yeah. But like, no, wait, just my body weight. And I just kinda get into the squad position. Just hold a little bit in what do do it. It's not heavy is not something explosive. So my body's not feeling the stress, but at the same time the muscles are working. Yeah. So then they kind of wake up so all the muscles strand star, waking them stuff like that. And and that's just an example. But I would do a lot of stuff like that. And I feel like it's still gets the blood flowing, but my heart rate and everything is still like low relaxed, and I think even that is like, you know, you tell someone eighteen twenty hey, let's do that kind of work on the Denver. Like, no, I want to lift heavy ways. I wanna pump and push. And so it's like getting that message out that you can actually get a good workout defective for your body and healthful for your body. Without having to necessarily put under that kind of stress. You. Yeah. I was the same way. I didn't. I was not feeling the whole other offered to us in university. And it wasn't until I retired that I was just like, oh now, I see it. It's just as hard especially at the you're like, a technician as far as athlete or whatever because you have to concentrate, and you can't think about anything else, which is good thing about yoga words. Like it. You're thinking about what happened before he started yoga what you have after yoga, then you're not gonna be able to hold those positions. So it's very I mean, I'm a believer of it. And this should come come down black dog yoga. That's what you get. Jenny Brill just saying, yeah. And you build muscle. And I think a lot of it is people think you can't build muscle doing you. But you can't do certain things. But you know, they're saying that you can build muscle Yossi yoga is actually a rated as a moderate intensity, exercise and the flexibility and the flexibility in the balance you should be able to touch your tells for the rest of your life. Yes. And that is actually one of the kind of predictions of early death is not being able to do that. So so they're saying, you know, yoga's really good for this. So give it a try, and there's different types yoga's, if you try it, it's not for you. Try a different they have trap. Yo now, they haven't. They haven't. Trapped yoga they have goat yoga. They have naked yoga. They have all different variations of yoga do yoga Pilates yoga weights. There is yoga in the pool. There is whatever you want. I did try hot yoga before. But it was like in the middle of the summer. It's like already one hundred sell side. Hi yoga, and I'm thinking like, yeah. It's hot. Like contract. Doc returning. So I go inside this role leaders needless to say, I didn't finish who's already one hundred dollars south one hundred and fifty minutes. Can't even pre game stretch. I done how yoga it defies the mind. Because you like this is something I would never ever rationally do living in LA. But it works for like the wintertime. For but you will drop weight quickly. Of that. I will our next door is a little less healthy. But it looks like and we talked about it on the show is the epidemic of e e cigarettes and vaping, especially amongst kids. And the FDA has now come out with some new numbers showing at least in November that eighty percent. There's been apes rise and high school kids now vaping and fifty percent rise Risa middle middle middle school kids who are now being as well. And so I know that you have taught in high schools with a problem you saw then and were you able to communicate to kids anything about this? I think there was a kind of like a transition where you know, at one point people thought smoking was cool just regular cigarettes. And this vape thing came out and not only was that kind of like smoking still, but people are saying, it's not bad for you. So I think that was mistake number one. And then it gave the kids like more leeway. So I started to see that transitioning kids may tell them whatever you it goes in one ear while the other seems. But I think what's really important with dealing with all the time. Is you have to live, by example? You can't tell the kid to do one thing. And you do something else and not saying what we should be doing. But for me, I'm not a smoker. I, you know, I never vague or anything like that. And I just kinda especially being athletic and just kind of like connected with the kids on that respect. I think it does affect them enough to be like, hey, well, you know, what Mr. hunter he's doing this? And he's kinda cool. Maybe I don't need to. I don't need these these smokes or these vapes right now. So I think it does help, but we need more of our role models constantly doing that. And just instill in like like, you know, living, by example, type I imagine you'd probably teacher. They looked up to you know, Jack in the room that does help. So what they're doing Santa Clara county is there. Enlisting some students to voluntarily speak to their period. So there. Enlisting listening to students train the students to voluntarily speak to their peers because they are learning, by example, but it's a little bit easier. When you see from someone who kind of looks like you're kinda resembles you take. I mean that your peers that it's going to be usually the atypical peers, and you don't if you don't side with them. Because no matter what school you go to pretty much live. There's always different sex. So there's people that you might look like you would not be right. But if it's someone from your friend group, you'd be like, oh, maybe I'll think about it from your finger, but what they're not willing. They're gonna try teak. Bring somebody like who's who's older or somebody who's in the public guy or social media or get stuff involved where where kids go to all the time. Yeah. Then somebody that I don't rock with we're in the same class with. All right. Good for you, whatever. So well, I'm commending county for I'm always on. I'm always on. Honestly, I do think that you know, it takes it takes a village to like train a child. It really does that. So all these different things are not going to touch every student. Yeah. But the more you do that the more starts to evoke the change. So I think. Yeah. Like, you're right. They don't rock with this kid or they don't like him for whatever reason they're going to do the opposite kind of sort of. But if the if the parents are in a certain fun on the wavelength of the faculty straight. Now Russia Soling out after a while. Then guess what that atypical student is now the cooled student now what happens is more and more kids be like him, and then they become role models as well. It's the trickle effect. Yes. There we go. We go. Now. Speaking of targeting. Our youth troubling is finding that eighty eighty six percent of ads are being aimed at black youth. Junk-food attribute aimed at black youth. Eight two percent Hispanic youth. And they looked at thirty companies amongst them craft Hines mills her see your branch include KFC Pizza Hut. So and it's been growing twenty thirteen now to twenty seventeen and so this has been very problematic that they're really focusing on our youth and even the health spending there about three percent on healthy messages. And only one percent of that is reading black kids and zero almost zero percent reaching Hispanic kids. And so I thought how troubling is this for the minority community. I know you very involved in bringing these minority stories to life and just how you've been able to kind of talk to minority youth, especially as a teacher and kind of give them that healthy message. Well, one of things not to like bad than school systems or anything like. That. But one thing that I did notice kind of a pro and con they started bringing this thing to call it nutrition into the school system. So they after first period, whatever they get like an extra ten minute break. So they can eat some food, basically. But some of these meals that will come in. I mean, they really weren't in healthy. They might have like one fruit in there that was of cool like a miniature half. But whatever I understand his budget cuts and all that. But then there would be other stuff in it would be processed. It'd be like a Muffin cake or something like that like last for three years all the process stuff. And there's no good for the kids. But we're calling the nutrition. Yeah. So I think one again would in educational system was educating people, you know, what I mean? And I think that's kind of a false positive when you're like say, hey, there's a nutrition, but it's not really nutritious for you. So that's that's number one. And obviously a lot of schools at work with they're going to be in in in minority neighborhoods and stuff like that. So when I see that it kinda like it upsets me a little bit because we're not doing Justice. It's like, oh, yeah. Well, we put this money here. Now, we're gonna we're gonna put money to this to this program, but the program's not prone, and I think a lot of his political as well. Of course. You know, these these companies had that mass produces stuff manager trying to make money at the. Oh, it sounds like a good idea. We look good. How much money can we make all? Yeah. By the way, this one is cheaper than that one. You know, how it goes? We just got to be more proactive to like recognize what it is. So that we can have a voice and to say, hey, and again with the kids have these kids, and they would they think okay breakfast. Now's nutrition I'm gonna eat breakfast before second period. And I'm getting a half of an apple because they'd be literally like that big and this Muffin like no that's not breakfast snack. And you know, matter of fact, if I should even really eating this Mufid every day, and how did you insulate yourself from these messages growing up and even as an actor? Now. How are you insulating yourself from that the latest craze or figuring out I guess, wait five years? But when you get these messages is there something that you doing investigating to figure out is this for me. Yeah. You know, what I'd like to say them well educated person because I worked at school system and everything, but you know. There's so much information out there could confuse you it really can't. I mean, that's the truth. So you got so many studies so many different things I think we over think it, and we just gotta go back to the basics. Again, you really gotta be in tune with your body. But again, if you don't really do much with your body, like I think for an athlete or someone who's very active you your body needs that nutrition all the much more. So you could be affected by a little thing. So again, it just goes back to. Yeah. Long as active. I'm getting up early. I'm still doing my workouts and stuff like that. I try to be have a good habit of my sleeping patterns, and then I can tell wait a minute. You know, what I've been trying to sting? Got this new brand of whatever argues is not working for me. Okay. Let's cut back and try something else. We'll go back to what I was doing. Good advice. Good advice. And what I want to know. What how did you make this transition now from being this teacher part in this these kids? Hey before we continue. I do want to let you know that we bring you all this content free of charge without ever expecting you to pay for it. But the one way we help. Keep our doors open amazing sponsors today. I want to tell you something I'm really excited about because you could sift you hundreds of brands of the big bucks stores only to pay for premium, and unfortunately, disappointing quality because planned obsolescence where things are only meant to last a certain time, and you don't really get what you're paying for especially with the brand name. So honestly, my most frustrating experience with doing this. I bought a drier two years ago, and it's only expected to last two years or you buy that shirt that you really love and then three times to the wash. It's already ruined. Rand lis- offers better options for the things you care about organic fair trade non GMO gluten free and vegan food items bakeware made from professional grade aluminum steel by a family owned company in the USA, cruelty, free, beauty and personal care. They've cut out the unnecessary middleman cost of traditional retail to get you higher quality products at a more affordable price all without having to leave your home also brand list gives back and gives you a better way to join them. Because every time you check out at Brandis. They donate a meal to someone facing. Hunger and they provide millions of meals a year this way through their partnership with Feeding America right now. Our listeners can receive free shipping on orders of forty eight dollars a more at brand Louis. Go to brand-new dot com forward slash listen and receive free shipping on orders of forty eight dollars more you guys don't have to wait. It's high quality goods we really enjoy it here at the studio. And again, they set you up with high quality stuff, and we set you up with high-quality content. You can't lose go to brand-new dot com. Forward slash listen back to the show y'all and then going into acting transition. First fitness throughout you know, because it's like, what's the incentive you like, wait a minute. I want to get into this. You know, I I know sounds funny. But. The whole time. I was teaching. It was kind of like I was still like on a stage or in front of a camera. It was just instead of filming something fictitious, I'm dealing with these students every single day. You gotta there's a certain way that you have to carry yourself certain amount of knowledge of certain amount of professionalism. And at the time that was got and get an audition every day like I was going to like teaches class, but for me that was still like my prep, and I and I really looked at it that way and a lot of times, you know, what the lessons lesson plans nowadays and different things that we have to you know, bulletins come in. I mean, it's like cold replace, basically. So I'm taking this. And i'm. The class in reading some not just read or just got fifteen minutes ago, you know, right before class. So I did that. And I knew that once I would make the transition. Obviously a Tyler Perry show. You know, bless me with that ability to do that. I know always want to still give back. You know what I mean? So I was like, you know, I'm going to deal with kids for the rest of my life, just in a different capacity. So I think really what's happened is kind of prepa me to understand, you know, more kids, we think we remember when we were kids and like, oh, yeah. This is what I went through. And you know, I'll never forget an true. But guess what new generation new different new things and it allowed me to be immersed in it long enough to still be in tune of what's going on. So now, go back to the schools. I remember I'm like, oh, yeah. You know, what even like little things with the phone? We have phones. You know what? I mean, we just didn't like you know, what I mean, they they were around but every kid. Seven I wouldn't even go back to. No seriously. You know what I'm saying? So like the kids attention spans are so small so short, and it's not their fault society. You know what? I mean, we throw stuff that left right and center. So now, how do I keep their attention long enough to teach them anything that matters? You know what I mean? So now when I go back, no house schools these kids are not being disrespectful. They just can't and is trying to reach them that way. That way. And I would say probably all of you kids. Ask you for work on advice. I imagine. Yeah. Yeah. That. This is your what do I do? But what brains were they taught high school? Okay. I think elementary elementary school teacher. So I have reason I ask questions do my research. I saw in the Steve Harvey show. And this guy comes out service. And he's ripta shreds. I'm saying, wait a minute. What did you prepare for this appearance? I wanna know. Absolutely nothing. Just. Just. But then what's the diet? What did it look like what is training? Look like for you. What is your nutrition the played for you to maintain this? Because I have a sports background everything. I just that was a way of life was so long that I don't think I can function properly if I'm not like working out at some capacity. So I guess for now just kind of always been shape. But yeah, the the day I had to be on like Tyler sorry Steve Harvey show or even now like show now just going to be some sort of. We'll see so. Extra for that. Honestly, I. Obviously, you still go to try to do a little bit more like two days before going to be. All right. I do extra sprints, but I cut down like a little bit liquids like water does taking a little a little bit of Goto regiment, right before a scene, or you know, what I do. I want to say that. That's not the truth. But to there's people out there that a lot more than I do too. And some of the things that I hear from some of these guys, especially like, the real fitness model and stuff that they they talk about I'm oblivious to. I don't know. I've tried everything. I'm like into everything. Right here. In fitness, obviously is sort of your bread and butter, and then, but even as an actor to like, you still have to maintain that level of fitness because it's the next job. You know? So how how enjoy your role on the season on man. Listen, you guys going to be in for doozy. Twitter was lit up last night. You know, what they're really excited. I mean, we took a little bit of hiatus from Erin. But yeah, we episodes are coming up. Just the things that happened more and more and more and more more in depth, and for my characters kind of cool because I came on new to the show. So I didn't know much my character is just being introduced all these characters and manage it just really Glen just gets worse and more and more. He can't get out of stuff to have as many as we'll see like real soon that it's a as a trip. Who's do? Don't know. We're gonna have you back on after. So oh. Oh, definitely man. This is this has been a real tree, but we have fit club fives. And we like to do reality five rapid fire questions and get your first your first response. So TK takeaway. Yes. No, maybe. Last person you text. My mom. Let's say. Listen, mom might not have gone through. But I was texting I haven't finished yet. Dream dinner guests tree dinner desk. Gabriel union favorite junk food. We just got finished talking about junk food. I know peach, peach, cheats, what no non organic, peach that's junk food. That's my favorite food. Did. Okay. What do like chocolate? Okay. So does better. The first thing I thought about it. Again. Not not at all. What would be your last meal? You know, probably salmon wildcard, some sweet potatoes. Yeah. Some spinach. Going out going out in style. He's gonna eat them. Gosh out of all the people. I've answered I have to say your answers in the most bland. Hey, just say all right. So I think it was bland. Got a role model. Day. Just letting you know, this is really me limb, by example, healthy every single day, your junk food should be peaches are into Apple's non-organic healthy, go get the organic even if it's the last day. Very lesson meal. You want wild caught said farm. At least union. Spice you last. Album for the rest of your life boat. Would it be one? Yeah. Naza? I am. See? Oh. We want to thank you for. Joining us has been great happy, man. Gotta come back got to find out a little bit more this season and get some more workout. Definitely thanks for joining me again, guys psychosomatic and find me on Twitter, Instagram, Snapchat, is strong everything at TK trade ad could find me I am j hunter guys win. Win. On behalf about we would like to thank you for tuning into black Hollywood live the world birth digital broadcast network, devoted entirely to urban entertainment culture. Check out our black Hollywood live patriot even more great programming in amazing concert and be sure to subscribe and like our channel. When you do. I'm your host Mickey name, you can find you know, social media at KiKi boom-boom black Hollywood live black Hollywood live Holly.

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I Have Questions: The Stuff I Should Already Know

The Thinking Atheist

1:14:43 hr | 1 year ago

I Have Questions: The Stuff I Should Already Know

"Thinking atheist, it's not person. Symbol an idea. The population of this country is going through the rule rejecting faith. Challenging this sacred, if I told the truth, it's because I tell the truth because I put my hand on a book and Mehta Whistle and working together for more rush in all world, take the risk of thinking for yourself much more happiness fusion wisdom will come to you that way. Assume nothing. And start thinking. This is the thinking atheist podcast hosted by Banderas. Greetings onto the. My, brothers and sisters in Heathen, re so glad you're here. Today's broadcast is going to be a fun. It's about ignorance now. We're not talking about like stupidity. Ignorance can be fixed like you can replace ignorance with knowledge. You can teach an ignorant person about something. This is not the same as just being an idiot. Somebody who just seems to operate in their lives with the IQ of a doorknob. You know you give them the opportunity to do the right thing. Say the right thing. Make the wise choice. They will always drive over a cliff amount, not talking about that. I'm talking about ignorance, not knowing maybe you were. were, never taught. Maybe you were misled by bad agents or bad information I was reading this article about the deep fakes, those alarmingly realistic fake videos that show people saying things. They never actually said I mean. Wow, it's alarmingly going well produced and I mean that in a terrifying way I mean we're coming to actually we're already at the point when it's so hard to tell the difference. Sometimes just another piece of the misinformation puzzle right a lot of nobody you. You but I get overwhelmed. Sometimes you see a clip. You read an article you look at a photo you gotTA verify. Is this real will? How do we do that? The great courses plus has a fantastic resource. It's a series designed to help us separate fact from fiction. The course I'm talking about is called fighting misinformation digital media literacy. This is more than just a tap on the shoulder. That says hey go fact. Check go to snow pts. The series gets. Gets into how our brains process information cognitive bias how that works how we might be predisposed to accept something. That's factually wrong, Outta. We deal with bogus websites in fake reviews in the box in the scammers and the trolls, fighting misinformation is one of just thousands of lectures at the great courses, plus on a huge variety of issues it streams to your computer, your laptop, your tablet, or be the great courses, plus APP, feed your curiosity and get some good in. With the great courses, plus right now my listeners can get a free trial a free trial with unlimited access, but you gotta sign up today at my special. U. R. L. To get started. The great courses plus dot com slash seth. Don't wait they. Great courses plus dot com slash seth. Would be further along in my life right now. I remember the confidence of youth. You. Know everything you're young. And if you don't know what then, it's not anything you really needed to know and so screw it. I'm a middle aged man. I look around at the world and I'm like I should know more stuff. I should have a better grasp on the world I. Live in yet. The more I learn, the more I realize how ignorant I am and it scares me. Case in point. The national debt. Maybe, they just throw scary numbers at you all the time of the national debt out of control. The national debt is twenty four trillion dollars. You can't even process that like twenty four trillion trillion. Okay or wait a minute so billion thousand million. And, a trillion is a thousand billion times twenty four. That's twenty four. Trillion dollars national debt. Twenty four tribute, and the number is so overwhelming. It's like trying to comprehend the universe. The human mind is not able to really process it. And then he started asking other questions. Okay, hang on. The national debt were in debt. To who who are we in debt to the United? States owes money to WHO. Okay. Let's got to be other nations. this is a trade deficit of some kind to me. We've been trading and we. How did we get into debt in the first place? A who do we owe the money to? Specifically I don't know. I mean think about. Do you know who we owe money? You know. Who who do we owe twenty four trillion dollars to? And what happens? If we don't pay. Like. Okay fine. We are the United States of. Some would argue that we are the most powerful and influential nation on the planet. I'm not sure that's the case. And as we discussed in many instances on this show, we fail in a lot of the metrics for greatness across the planet. You know we we aren't all of that or at here in the United States, but we are a major superpower, or so, the United States has a twenty four trillion dollar debt. The what happens when we look at our debt collectors and say screw you. I'm not paying. The somebody own us. Like this someone foreclosed on the United States. And then we just get annexed into another country. What happens? If. We can't pay the because we'll never pay it. Twenty four trillion dollars shitting me. This is like a magnification of. You have a twenty thousand dollar credit card debt at thirty percent interest, and you are paying the minimum payment of twenty dollars. The interest is just exploding exponentially. You'll never get out. You'll never get out from under this debt. It's always you're going to suffocate. The creditors are going to come. They're going to take your house. Your cars furniture they're going to. Ruin your credit rating. You will be ruined. Does this happen to the United States? Because at some point, if we owe twenty trillion dollars, somebody would be like. Hey, hey, you know what the bills do, man. Debt forgiveness that's out. It is time for you to put up or shut up or Or what? What happens if we don't pay the debt? I'm fifty two year old man I should know this. I should know the answer to this question. Because everyone tells me how it's going to ruin our future where Mer, passing this debt often to our children and their children and their children and If what does that mean? I mean how much will that be in another ten years? What would our kids even remotely big to do about it, I don't know I have questions. I've questioned I do not know the answer to you ever do that. You ever dislike around and think I should know this. This seems important. Why do I not have this in my knowledge base? So then as a rationalist, you decide to get educated you go ask the question well. What is the national debt? Well, it's it's an integral part of our processes economically it. It relates to our Gross Domestic Product. Okay all right well I, I vaguely get gross domestic product, but. Is the product at actual product. To gross domestic product, but what the GDP? Okay, let's let's get our head around that. The GDP, the total market value of all the goods and services produced within our border in a specific time period all right I got my head around that. We get GDP are essentially. It's the value of all the Shit we do and sell the GDP. The deficit means that we're as a government as a nation spending more money than we are earning in terms of taxes, etc.. So we try to compensate by issuing bills and notes and bonds, which are like taking out a loan, and we borrow from investors, both within and outside of the United States whether it's corporations, financial institutions governments all around the world. Okay, now it's starting to make sense. Hang on, so we are spending a shit ton more money than we are earning in terms of governmental the revenue. We can't sustain it, so we go out and we borrow from anybody and everybody and their dog. We borrow we borrow we borrow, and this debt accrues okay so now we owe creditors twenty four trillion dollars. Of what. What? Okay. Where does that end? How do we get there to begin with at some point? When you know you hit the first trillion, do you stop? Look around and go you know we. We need to get a different thing going here. If you were balancing the checkbook in your own living room, right, you're doing like financial budget for the year and you're like oh honey. Come here, look at. This looks like we're going to be a trillion dollars over for the. The year at some point, would you not look at each other and go? You know why we need to trim the. We need to cut back no more eating out honey, no more restaurants. You know what you can't have that. Five hundred dollar battery powered Cobalt Electric Lawn mower this year. We gotta use the old pole start gas mortell. It wears out because you gotta make things last. We're going to be a trillion dollars in the hole can't do that. Maybe we need to downsize. Sell the House live in an apartment for a few years till we can get things balanced out, don't you think dear I mean otherwise. It's a trillion dollars in all at some point. Did the government not look around and go? Holy Shit. This jared looks like we're GONNA be down another thousand million thousand billion trillion dollars, I, don't understand. What happens if the government says I ain't pan? which is something that a lot of people are saying that we should just do it? What twenty trillion modest will be two hundred forty trillion? Nobody gives a shit. Nobody expected to be paid back. Let's just leave it. Let's just leave it, and let's go down to Daytona and have a Kager and just party like it's nineteen ninety nine, and whatever happens is going to happen, and we know the foreclosures aren't really gonNA. Come like they're not gonNA. Come and put a trailer hitch on the United States and repossess the whole country. We know that's not gonNA. Happen so screw. These are basics about my own country. That I should know more about I should be able to get my head around and I just I just don't. Ears another great example of something I should worse than the fact that I should know it. We did a broadcast. It's been a couple of years and I had somebody an expert on the show to explain it. I still don't understand. Really understand the difference between DC and AC electrical current. I what's the difference between plugging something in and getting electricity out of your cigarette lighter in your car, and plugging in two or three, prong a C. outlet into the wall of Your House I tried to get my head around this I thought, let's go to the experts I invited an actual electricity. Who explained it to me on the radio and I still have no idea enforce. Well. DC's direct current as T-. Well, that's an amplitude amplified current. NO WAY ALTERNATING I! Think. That's alternating curr. What alternates on this current? Aid alternates like it back and forth alternates. A weight! It's electrical `electricity. What's the difference between DC AND AC? I don't know I have no idea what's the difference between volts and amps. Like I'll be standing around. There'll be a group of guys and they're all this man. Talk well you. Working on my car had the Pistons out the the dodge pickup drug getting ready to try to get him Meyer and tearing her up, so she alternator and the. And the catalytic converter did this and rotated. The tires got her going went on. Put My gun rack in doing man stuff This is how we talk in Oakland, Dude, talk and Oklahoma and you know what I was in there, working in my house had to put a new. Light fixture in and all of sudden I realized that I had shut off the power at the circuit box and I got shocked I could have been killed, but you know watered ain't the voltage that kills you. It's the camps. Of What what? Are. What's the difference between the voltage? And the amp, so the voltage is like. The current. That's going through a conduit or a tube. Think the voltage like water going through a pipe. The AMPS! That's the force. That pushes the the pressure behind the water in the Pie. So it causes you to get more or stronger. Kick a voltage. Am I even close on that score like it ain't the voltage. It's the amps I still. Don't know that I understand what this means. You. Should know this by now. I should understand especially given the fact that I had a teacher who explained it to me in rudimentary terms like in monosyllables in the most basic language and I just sit there. Oh! I still don't know why they call it Bluetooth. He Got Bluetooth on your phone. Got Bluetooth on your. What on your your car? Stereo does a pickup Bluetooth. Is that a Bluetooth headset? We talk about it all the time. We just assume the WORD INTO OUR PUBLIC DISCOURSE I don't have any clue in the world. Is it called? Bluetooth? There's nothing blue about it. There's nothing to worry about it blue tooth. Oh. Whoa, let's solve this one. Hang on just a second. Google. Why do they call it? Bluetooth. We're GONNA learn something today, kids. Oh. There's a bluetooth dot com. There's a website for Bluetooth. The Story Behind how Bluetooth got its name. The article says for how innovative technology the name doesn't sound techy. It's not an acronym. It doesn't stand for anything. What does it mean? Surprisingly? The name dates back more than a millennia to King Harald Bluetooth Gorman's son, who was well known for two things. He United Denmark and Norway in the year nine fifty eight. And his dead tooth, which was a dark, blue gray color, earned him the nickname Bluetooth okay. So, we got a King King Harald Gorman the UNITER of Denmark Norway over a thousand years ago when he had a dead tooth, which was blue. And they called Him Bluetooth all right. We're tracking. Everybody with me here. Okay, let's continue on. Will in Nineteen ninety-six, the leaders of Intel Air Ericsson and no key got together, and they were talking about this new short range radio technology. This is going to allow different products and even industries to connect right using wireless short range radio and the meetings going on the guy from Intel Jim, cartage suggested Bluetooth as a temporary code name for the technology. As King Harald Bluetooth was famous for uniting, Scandinavia, they wanted to unite pc and cellular industries with this new shortwave wireless technology, a unifying thing and he just pulled it out of his ass, said Bluetooth. We'll just call it that for now. It was supposed to be a placeholder until the marketing departments could come up with the name that was really techie and cool. They were GONNA call it. radio wire. A somebody had called it panned for personal area, networking and fact Pan was the front runner. Imagine having a Pan, head, setter, Pan, earpiece, pan, radio or something. So then they went back to radio wire, but they couldn't get a trademark search done in time for the launch of the product. What we've been calling this technology for the past several years. We've been calling it Bluetooth I guess. We're GONNA. Stick with. That would just call it Bluetooth in fact. The Initial Bluetooth logo is it's a rune, and it somehow binds together the initials of this King Herald Guy. So when you see that his aroon with a Little Star thingy editor, somehow this represents the initials for King Harald Bluetooth Gorman. That's a great story to tell parties right? You can look like the smartest person in the room. Hey, you know where they get Bluetooth from. Don't Ya Yeah? What's King? Harald Gorman I. Mean Come On. Everybody knows that. United Denmark and Norway back in Nineteen Fifty Eighty at a bluetooth yeah. Yeah Opt He didn't know that well. You're welcome. You're welcome, everybody. Here's another example I. Just in the last few months have been learning how yeast works! We're like a lot of different people who have had more time at home recently few years ago. I began to fall in love with cooking. You know a guy who used to be the king of the microwave. I really fell in love with spending time in the kitchen and I enjoy cooking for other people and trying new things. It's been amazing. It's really been therapeutic. It just makes you feel good to be in their creating in the kitchen but bread. Breads intimidating. Brad is just straight up alchemy, right? I mean so much stuff can go wrong in takes so much skill and time I just always put it off. Think I tried a loaf of bread last year and it was like mortar. I believe you could have broken windows with it. And I got hooked on the Great British baking show. You watched that broadcast I think you can stream it on Netflix, except show will flat out suck your life. I'm obsessed with the Great British baking show. So we were talking to some friends about making sour dough bread. We're going to attempt. It turns out our friend. Karen has sour dough starter. So she brought us a jar. Now I'm sitting here looking at this jar. Like what did you just gift to us? What what starter? Is it like yeast well. No, it's not. It's not well. It's kind of like yeast. Yeast it's starter. Okay wait a minute. It's starter, so it's doe. No, it's not though you need it for the dough. All right, so it's yeast, but not really used, and you have to have it before you can make the bread. And then she looks as dead in the eye, and she says and don't forget to feed it. I'm sorry. What You have to feed your starter. It's Goop. It's just goop in a jar. You what do I feed it? Well, you take some of it out and you put in flour and water, and then it ferment fermentation bubbles on itself. You have to feed starter so now. I'm in a whole new universe. Okay, a man who had already been confused about yeast I'm sorry things that are floating around in the air that you can catch using water and cloth and bowls and Shit I mean. Yeast is just always flying around in the air. In, my mind, you know what I pictured when someone told me that he used to always is out there. Flying in Air I think sea monkeys. We. We start in our house. We call them air monkeys. I, just picture little creatures floating around in the air that you catch and you used to make bread. So is sour dough starter. Is that just a goop that contains captured air monkeys? I don't know all I know is I go in I take a little bit out. I put in some flour, and some water and I. Give it half a day, and it almost doubles in size. It's fascinating, and then you use that to start your sour dough bread. We made bread in this house. We made a loaf of sour dough bread. That would change your life first of. Of all it takes about two days to make it happen. You know your folded over, and then you wait thirty minutes and you folded again in your wait thirty minutes and you folded Gannon. You add some flour and you put it in the fridge and you wait all night and you do this and to do that and you're wondering if it's worth the trouble, and then when it goes into the in the house fills with the aroma of freshly baking bread. And I'm guessing the corpses of thousands of air monkeys. You take into your body through the olfactory organs, the wonderful heavenly smell of bacon sour dough bread. Anticipating the moment when the oven door opens, and you bring the bread out and let it cool for about an hour, and you take your bread knife, and you slice it into. There's a hard crust and inside a wonderfully warm and soft and sort of air pocket, T. Substance, which is homemade bread, and you lather it with butter, and you eat it slowly because you want to save her free single bite, it is having if heaven exists. It's homemade. Sour dough bread I'm obsessed I can't stop breaking the stock different recipes. Let's try a different recipe. Let's try a different kind of bread. Let's do this. Let's do that. But if you ask me at the beginning of the conversation, Hey, what's yeast I will look at you as if you would ask me to give you an example of one good. You've a bowl film. I can't. I can't do it. I cannot do it. Yeast. Air Monkeys. They're floating around in you. Capture and somehow they caused you to have fermentation bread. That's the best I got. The that's all I got dog. Now here's one more layer to the weirdness. I learned I was told that you know your starter. The goop that you start this hour though the sour dough starter, you're supposed to name it. This is a tradition that spans hundreds upon hundreds upon hundreds of years. People name their starter. We named Harris. Herbert! we heard somewhere that Herbert was a popular name for Sour Dough Starter, and so this leads to some bizarre like twilight zone conversations honey. Did you feed her today or you know whatever got to feed her bird? Fed Herbert, but he's only about half the size. Herbert isn't bubbling. Don't forget to poor part of Herbert out into the trash unless you plan to make sour dough waffles with the Leftover Herbert you know what Herbert isn't bubbling correctly. Is Herbert Ready to make bread? This is how we talk in the Andrews Gettin. It's a strange universe. Using a kind of chemistry that causes me all kinds of intellectual headaches because I don't understand. But I'm making bread. I still don't know why we call it the civil war. Like the civil war, we learned about it in history class. We talk about quite a bit. My favorite documentary is Ken Burns's the civil war war, but wait a minute. Doesn't civil mean. Civilized. Polite, your mannerly. Civil war, six hundred thousand Americans died horribly during a civil war while I made kind of a mental bookmark on this one, and had the Miriam Webster page pulled up here on my browser. They obviously known for defining words. They actually have a definition page for a civil war. Like why do we call it? That civil began being used in the fourteenth century. Apparently, it's a variation on the old Latin word civilise which translates. Dozen so a civil war is a war of citizens or between citizens, opposing groups of citizens in the same country are I well. That makes sense. A Sevilla's war, or is it civilize? Now like Sevilla's civilised sounds like a like a disease like you have a terrible case of civilised, you need to take some penicillin. We'll go with Sevilla's. The. Latin word meaning citizen a war between citizens. We learn something new about the civil war on this broadcast. Natalie and I were. Sitting up the other night where propped up in the bed and browsing our phones killing time you know. And I was kind of propped up in a funny way. You know I was kind of awkward there by an adjusted, the pillow and Natalie looks over and says you're GONNA. Get a crick in your neck. And all of a sudden I for the first time in my life I thought what the Hell is it creek? I A creek. And your neck. Miriam Webster says the definition of a creek. A painful spasmodic condition of muscles as in the neck or back, okay, a creek a brick. Apparently according to Wick Shimeiri. This apparently goes back to the fourteen hundreds, the creek likely related to an old norse word. Crikey. Crikey or quickey K. R., I K. I this old norse word means nook like abandoned creek. Core, creek right you see the bend in their creek or the river. It's a band. I, Dunno, it just seems a little sketchy to me. So when you've got a crick in your neck, you are essentially invoking old norse language that refers to a bend in a creek. Does that wash with you. Like a creek in your, you have a creek in your neck. Okay I. Do. We say it all the time? We don't even know what it means. It's a creek. I. Don't know what the Prostate Dazs. Wear prostate exams a fifty year old man time for your prostate exam to make sure you don't have prostate cancer. Only men have prostate. What does the prostate do Hallo fine? No, I have no idea. Fortunately for you in me. We're going to talk a lot about bodily function because you know we can. There's a prostate cancer foundation website, and it's got some explanations someone. Browse through this and summarize. The prostate. Is a small squishy gland. It's about the size of a Ping Pong Ball. It's located deep inside the Groin. It's between the base of the Penis and the rectum. Just kinda hangs out there. Apparently in that middle space okay. The prostate is important for reproduction. It provides the seminal fluid. This fluid mixes with sperm. The sperm comes out of the testes testicles. Okay, so think of a water slide. This is how I learn things This is a water slide all right, so you have the little person on the rafter on the little mad or whatever on the slide. That's the sperm. The seminal fluid is like the water on the water slide that helps the little sperm. Get wherever they're supposed to go. And that fluid the water on the water slide that's made by the prostate. My given that ride. This fluid. It's got enzymes in it. It's got to something called. P. S. A. It's got zinc and citrate and fructose. Fructose. Like sperm sugar. Apparently, these substances give the sperm energy to make the journey to the egg, so they are nourishing the sperm as they travel out of the testicles toward the egg for fertilization. There's also antibodies that might help protect against things like urinary tract infections. It might protect your sperm from bacteria and other pathogens. So now it's like we're sliding down the water slide, and they put like Peroxide and alcohol and Shit in the water. To protect you from germs as your sliding from the top to the bottom. Okay, we still tracking the prostate. Now as men get older. The prostate sometimes gets bigger. Apparently, it enlarges this ping. Pong ball turns into. I don't know baseball. I mean it just gets bigger all right. This is often. Why older is have to stop whatever they're doing and go pay every fifteen minutes. These prostate cells they multiply. This is not a cancerous thing usually. They just multiply. There's more of them, and this enlarges the prostate, and that puts pressure on the your e through. Down the slide all right, the ARETHA is the water slide that all this stuff sort of goes down. Okay so the water slide through which all the urine has to go. This gets squeezed by your prostate when it gets big. And this narrows. The water slide is tons of pressure on it, so it narrows that corridor and the bladders got work harder to try to empty itself. This means the bladder muscle might be flexing right. It's trying to push the urine through and all this muscle use actually makes the bladder stronger and thicker bills up those muscle walls. It's more substantial insensitive, and then it comes to a point when sometimes it starts to contract, even when you're bladders, not full right, so you feel this urge to P., even if your bladder might not actually have to p. Everybody tracking all right, so let's recap. The prostate makes fluid that carries sperm and might help keep the urinary tract free from infection. The prostate gets bigger as men get older. This makes the urinary tract. Be Alike. It's being suffocated. It's being suffocated by this angry, squishy Ping Pong Ball, and then the bladder overreacts by getting all big, Mosley and overreactive the prostate. So the next time you go in for the annual Cheka. The middle aged man, annual checkup, and the dog goes over to the little box, and he grabs the lube and the rubber glove. Just think about the Squishy Ping Pong ball that he is accessing through your rectum. And you're welcome. Here's one more related to male reproduction. This is courtesy of John on facebook. He had this question he said. How is morning would happen? You're familiar with that term. Right morning would morning would. Will if you are unaware for any reason. Frequently when men wake up in the morning, they have. Even know how to say this like. Men. When they first wake up in the morning. Sometimes have A. A woody okay. A STIMULUS PACKAGE A? Swelling ten is what they have. A standing ovation, the hard floppy. The flag is at full mast. They a breakfast Burrito. Okay, they have an erection now. Hang on just a second. Why do men get erections in the morning? I don't know. I don't know. Let's figure this one out. Hang on, just a second why? Do, men get. Iran. Wider men get erectile dysfunction. No. That's auto fill. Erections in the morning. COMES RIGHT UP. Yes sorry, that's a play on words. It comes right up. It's health line has an article. Go there's a medical term for this phenomenon. N. P. T. Nocturnal penile to msnbcs. I'd rather call it that. Then the breakfast Burrito. I'm just saying. It's common in younger men. It is experienced my men of all ages. Many people assume a morning erection as a sign of sexual stimulation. This is not always the case. It's likely a response. Your body has to one of several natural occurrences. Morning would can be prompted by physical touch. Even when you're sleeping, your body still reacts to Stimuli. So let's say you're lying. They're. Totally Asleep totally unconscious. Your partner grazes against you as you sleep, and then the body does what it does, right. It's a reflects. Hormone, shifts may cause. This testosterone is highest in the morning. Right after you wake up from Aram Sleep. So you? Testosterone is highest first thing in the morning. Right after you get up brain relaxation. When. You're awake. The male body releases hormones to suppress erections. Art So when you're out and about doing what you do throughout the day going to work or mowing the lawn or Whatever? The body is actively working to keep men from getting a boner. They're awake. That makes sense right I. Mean it's you know you don't WanNa Walk? You want to be at a party. You know saying you don't want to be at a board meeting or something like that and you're in a non sexual situation and it's like. Oh, I get that and when men sleep, the body relaxes, and it releases less of those inhibiting hormones. The body doesn't feel the need to protect you from embarrassment as you sleep, so it's possibly more likely that you will react. Physically health line says morning erections can be a sign of a properly functioning blood and nervous system around the penis. This is good news for men right I mean if it happens to you, you wake up in the morning and it happens you can. Perhaps you know breathe a sigh of UNIM-, Barest relief you know and you can just tell yourself congratulations to me. I have a working Venus. Thank you John. Thanks for taking us on that little ride. Pre shaped that I mean it's interesting. One of those things you wonder about the, why does it happen? Now while where in this particular region? Why do we call it the fly? Hey you're flies open. Zip your fly. Wait a minute. No, it's a zipper. But we call it a fly. We always call it a fly. Why are your fly open? It's like saying your swim is open. Your lunge is open your climb. Is Open. This makes no sense when you stop to think about it. I look this up parents. It comes from an old English. Word flowing F L O, w a an flow to flow at also came to mean something that attached by one edge, so you've got a flap, and it's just sewn at the top at the bottom that was adopted by nineteenth century Taylor's. The fly was any flap of cloth attached at one end to cover an opening and a garment your fly. Now that sensation that you're feeling in your skull right now. That pressure. That's just your brain expanding like all the new knowledge is causing your brain to press against the skull as what you're feeling right now. We know what we did not know. And there's still so much that I. Do not know. I don't even know how. Aspirin works. Like my head is killing me honey I need to go and take an aspirin. Most people take. Like the TYLENOL and. Trent Excedrin, Ibuprofen, whatever I mean. We've all got aspirin in the medicine cabinet. Sometimes I'll take an aspirin for a headache. What's up with that like I? You take it. It's like a magic pill I ever headache i. take an aspirin and headaches usually goes away. What's that about I? Don't understand I. Just do it a creature of reflex I'm a creature of habit honey. Go take an aspirin battle. Get rid of the headache I've heard it has something to do with relaxing the blood vessels or something like the blood vessels restrict, but have I really ever stopped to understand. Why do these magic white pills work on headaches well? Eco Trim is a brand of aspirin and they've got this educational page of fine I mean they make aspirin I'm guessing they're qualified to explain aspirin now. It's a long page so I'm just GONNA summarize and we're going to learn together right now. HOW ASPIRIN works, you're ready. We gotTA start with pain. Like what's pain? We feel pain, but why? Well pain sensation results when the nerves in our body send these electrical signals to the brain. Let's say you've got an injury. Right ear in the kitchen and you've got your bread knife out, and you are slicing your new Lee baked sour dough bread, anticipating that I to bite, and as you slice the bread shit. I cut my finger gate nasty. Cut on the finger the way everyone says shit when they cut themselves with the bread. It's just our shit. All right, so you cut your finger. The damaged tissue is released. These little chemicals called Prostate, gland INS. And these prostaglandins caused the tissues to swell. And also because these prostaglandins are apparently little assholes. They intensify the pain signals that come out of your nerves. They actually make the pain a lot worse. Thank you very much now. Prostaglandins do a lot of important and beneficial stuff, relating to blood pressure and getting good air flow to the lungs and. Gastrointestinal staff at Sarah, but right now I'm talking about the pain. And that's why I called the prostate gland, and the little assholes there because. This doesn't have to be they. Just send you a message that your brain would receive. Hello, you have an injury. That may be a problem like if I was an intelligent designer. I'm God. Looking down. I would have created a system where you know without question, you are seriously injured in some way, but it doesn't send you into a debilitating screaming fit where you are possibly incapacitated because of the electrical overload to your brain. That's just my take on pain, okay? Aspirin chemically blocks the effects of certain enzymes that create them. All right, so you have less of the little asshole prostate gland. And if you have less of those, it means you have less swelling, and the prostaglandins are not blasting your existing pain signals through a guitar amplifier. Okay, are we tracking? We got pain. We got swelling. Aspirin blocks chemicals that amplify the pain and the swelling. Now headaches come from a lot of different places. They can be caused by everything from is strain sinus inflammation like the sinus headache congestion, 'cause it tension headaches, migraine headaches hormone headaches. Headaches can come from illness or stress the environment, even the genome. You can have genetic reasons. You've got headache, so this is a really complex thing. Let's talk about the standard headache. Standard headache pain comes from a mix of signals between the brain and the blood vessels, and the nerves that are around them, and this is not totally understood even today. For reasons we don't fully understand nerves in the blood vessels, and in the muscles of our heads turn on. When they switch on, we see the production again of the little assholes. The prostaglandins produced in swelling and they do what they do. They amplify the pain and they make you feel like a monster truck just parked on your head. So aspirin comes in to save the day. It blocks the production of those prostaglandins so that the pain is not amplified, it reduces the pain of this is of course, an explanation that is probably giving the doctors in my audience a headache. Are you screaming at me? Are you desperate to dial in and tell me how wrong I am? I mean I got this from the aspirin website. By the way, why do we continue to hear that? If you take an aspirin a day, you might help prevent heart, attacks and strokes. How does that happen well? Aspirin works as a blood thinner. Essentially. It prevents the platelets in the blood from clumping together. CLUMPING is bad, right? We do not want clumpy blood. clumping can mean clotting in the arteries that means blockages to blood flow. Harvard University has published some material on how all this works. In the early stages of heart, disease cholesterol bills up in the walls of our coronary arteries. Now Hang on just a second. What's cholesterol mean? That's bad. Right or wait. There's good cholesterol bad cholesterol. Somebody like me I just accept it. What's cholesterol I don't know. Let's clear this up before we move on cholesterol. Is this waxy fat like substance? You can find it at all the cells of our bodies. And you gotTa have some cholesterol. It makes hormones. It makes vitamin D. it's got stuff in it. That helps us to digest our food all right so cholesterol. It's part of the healthy bodies machine. I guess that's what they mean when they say. How's your good cholesterol? Right and the body makes all that it needs. But cholesterol is also in foods that we ingest and that means. We get too much of this waxy fatty stuff in our cells, and that stuff can build up in the arteries. So these deposits build up and they trigger inflammation, and those inflammations make placker result in plaque that builds up in the artery that means there's less blood flow getting through. Because now you've got plaque that sort of blocking part of the door. The Heart's not getting all the blood it needs. You might get and Jonah or chest pain, and so if this plaque is built up sometimes the plaque ruptures, and it leaks those contents of whatever zenit and the bloodstream. And then tiny blood cells called platelets. They stick to the ruptured plaque. And then those platelets get all sticky, and they build up, and they clot in the artery gets totally blocked. Then, the heart muscles not getting blood. Now you're in full-on heart attack. Okay, so there's a lot of links in this chain. But you get the picture? Cholesterol waxy fatty stuff overloads. The cells starts the process of clogging the arteries, blocking blood flow to the heart part muscles starts to die because it starving to death now you're screwed, okay? Aspirin prevents heart attacks because it prevents those platelets from sticking together and forming the clots around the plaque and stuff, so that's breaking the link in the chain of all the stuff that's going on aspirin jumps in and says hang on. We're going to interrupt the process. We're going to stop these platelets these sticky platelets from all coming together and leading to blockages in the artery. So those people who are taking an aspirin a day. They're essentially trying to get in front of this process so that the build up and the clotting and the clogging doesn't take place now. I have to say this I have to say this. Preventative Aspirin is not for everyone. Our discussion today does not constitute medical advice. Please consult your physician. I'm saying you know come to this show. To get diagnoses, aren't we're just talking? We're just learning as best we can. Using Layman's terms. We're trying to understand complicated stuff using the most rudimentary of language. I doing with this stuff I mean this is interesting to you as it is to me. 'cause Uncle Seth is cracking open a knowledge egg on this audience today. I'm just saying. I've got more. I got more of this stuff. Queued up. Let us take a short break. I will be right back as our brains continued to expand. On the other side of this. How much could you save in one year by switching to Harry's? Now, you could save enough buy. Twenty six cups of coffee in New York City. You could get three deep dish, pizza, dinners and Chicago. You could get six months on your netflix subscription. How could you do this? Harry's delivers high quality razor blades as low as two bucks each. That's a fraction of the price of the leading brand and save you hundreds of dollars over time. Time I like the closeness of Harry Shave. I dislike what they do. The ergonomic handle feels like quality in my hands. The presentation is so nice. I often give Harry's as gifts on special occasions you can get. A Harry's trial set delivered right to your doorstep. Just go to harrys dot com slash the thinking atheist. Harry ships right to your door. All your grooming needs covered. Covered in one. Stop your blades haircare shower products. They're all at Harrys. Dot Com, and you can feel better about the purchase. Because one percent of proceeds set aside for nonprofit organizations and right now in these times, Harry's is donating a million dollars shaving supplies to hospitals across the United States right now listeners of my show can redeem their Harry's trial set at Harrys DOT com. com slash the thinking atheist. You will get a weighted, Ergonomic handle for a firm grip, five blade razor with a lubricating strip and Trimmer Blade Rich, lathering Shave Gel with aloe to keep your skin hydrated and a travel blade cover to keep your razor dry and easy to grab on the go go to harrys dot com slash the thinking atheist. Start Shaving and saving today. Patrons skip this show early. They get it totally commercial free and I so appreciate your support. If you are not a patron, please consider becoming one patriae on dot com slash seth. Andrews and you have my thanks for that. This is just a show about knowledge, not important stuff, not life changing world changing knowledge just the stuff that we do. We say we take for granted all the time. I've just had stuff on my mind. And I thought it might interest you I. mean if we're thinkers if we are thinking atheists, let's think about some of the things that we do and say every day. On My facebook page, we were having a discussion about all the. We don't know Diana had one. It's a little disgusting, but no less fascinating really. When you flush the toilet. Where does your poop go? Well, it goes to the sewer or the sewer system unless you have a septic tank than we know what goes out to the tank and it down and goes into the earth, but I mean what about a city dwellers right? The sewer it drains out. What is it go to a river or something I? Don't know the answer to this. Oh. It goes to a treatment plant are fine. What does that mean? What happens after that? Now I looked this up in advance. I didn't even know how to Google it right fortunately I just started typing in the phrase when you flush the toilet. It came right up. It popped right out. If you will pardon the expression, okay, live science has an article called. Where does all our poop go and we produce a lot of it? The average adult flushes about three hundred twenty pounds of poop down the toilet every single year. Turns out that our shit is surprisingly useful. Here's how the process goes according to live science, and again I'm paraphrasing. From the toilet, our excrement flows out through the city's sewage system, and that things like a catch all at the water out of sync and drains out of your shower and rain water from the streets, and all that stuff goes into the sewage system, and that stop gets routed to a wastewater treatment plant. So all this stuff kind of saddles into this nasty sludge. Now Hope. You're not eating. As we talked about this important is education all so all that stuff comes together becomes a sludge, and they have a series of tanks that they move this sludge through. Did you know? That there are tons millions upon millions of micro organisms that live in our poop. So in the stuff is sitting in this big sludge tank. These microorganisms breathe oxygen. I mean they don't breath. They take in oxygen and they also eat the bad stuff. They eat nitrogen and phosphorus and a lot of toxic type stuff. Bad things I guess. So essentially, this is a big chemical reaction going on in the sludge, and so in another tank, these microorganisms break things down even further they convert our poop into mostly water, methane and carbon dioxide. This horrifying lake of post poop. The the lake of liquid that remains. They take it and they drag it out in a centrifuge. And they use what's left. It's called a bio solid. This dried out bio solid. They used that stuff and a bunch of ways. They fertilize crops. Relax relax very little of it is used to fertilize food that we eat. It's like one or two percent of the crops that feed people are fed by people poop all right, so just relax over half of all processed poop is used for agriculture of some kind seventeen. Seventeen percent of the Bio solids they burn that stuff they it to produce energy. It becomes a form of natural gas. In fact, some of these wastewater plants are actually fueled by the POOP that they're processing is like a circular thing, right? They processed the POOP. It creates the gas. They used gas to run the machines. The process the POOP. It's an industry that runs on itself, and whatever's left ends up in landfills. Now there's a big push to stop taking the leftovers to the landfills, because there are some people who are like. Hey, wait a minute. We can still use this stuff to make more fuel to power the rest of our lives. This stuff that uses energy imagine you're at your house and you flush the toilet and the poop goes into some kind of. I duNno, it goes into a personal poop processor somewhere in your house, and it gets broken down in the microorganisms do what they do, and the gases are created converts to fuel, and that fueled then turns on your lights and run your appliances and powers your house I mean. You could tell people with pride I live in a Shithole. House, the powers itself with poop and you would, and it would be a good thing like this would not be something to be embarrassed about. Would you like to come back to the shadow? And hanging out. I mean I learn something new. I learned something new now when somebody flushes the toilet now you know what happens to it. Doesn't magically disappear, doesn't. Just go off and vaporize into the air. It actually gets used for a if you'll pardon the expression shit ton of stuff. What's another one? I've mentioned this before. I still don't fully understand. The royal family. I'm interested I guess and. Like, you would be interested in something in a cursory way, but I mean the royal family. What's the purpose of the Royal Family in the year? Two Thousand Twenty is just tourism. When we went to London and I'm admitting it outright. We went to London. Natalie and I went and visited Buckingham Palace, and saw the changing of the guard, and we were excited to go by the way. The changing of the guard is forty five minutes of the biggest nothing. You have ever seen. Stand outside the gate. We were we the sheep wool. We're standing outside the gate and all of a sudden you see somebody and they come around a corner. And they bring in somebody else, and then they do this. And they gesticulate in some way, and then there's a marching band. And they margin from some other place, and then they all move around and at the end of the day. They just changed outer few people. Had the pomp and ceremony all around. It was forty five minutes of the biggest nothing I have ever seen. But we were there. We were attracted to it. We were fascinated by it why? Somebody explained this idea that you're born better than someone else. This divine right of kings are you are shot out of the womb of a specific person. Therefore you are what? You're destined to be superior and to be given life of wealth and power and privilege. I don't understand that. I'm not saying I reject wholesale the idea of the Monarchy Oh. Cam Ninety. Our. Don't get offended by my questions, but. You know I mean is it? Is Tradition Enough? Does it. Give People Comfort this symbolism. You know for Queen and Country God. Save the Queen. Do they have any ruling power. Does the Queen involved herself? In any meaningful way in government, you know the managing of the structure of society and its constitution, or is that simply the prime minister and parliaments, and she's totally symbolic, and she doesn't really affect the process at all. I don't know over here in America I'm interested in and I'm fascinated by it. We're fascinated by the royal family. Oh, look so and so had a baby. Oh, there's Angel Song in the music plays in the tabloids. Go Crazy, and their photographs plastered across the planet and I'm over here thinking. How many babies are born every single day? What specifically is special about this baby? This birth I don't get it. while. It's tradition. Okay well. Is that really a good argument? Tradition does have its utility. Sometimes tradition can help to frame the human experience, but sometimes it's just dumb. What's that name shows somebody at the running of the Bulls ceremony, and it says tradition just because you've always done it. That way doesn't mean it's not incredibly stupid. There's another gem out there. It says tradition peer pressure from dead people. So, does the Royal Family genuinely survived? The tradition argument is at a worthy tradition. I have questions. And here's some irony. One of my favorite movies is a Stephen. frears directed film starring Helen Mirren, it's called the Queen. And a deals with the Queen's actions or lack of in the wake of the death of Princess Diana to hugely moving film. You haven't seen the Queen I. Think it may be on net flicks. You should check it out. I mean it's a compelling story you know. I had somebody on facebook. Asked this one. And at first I thought it was kind of nothing question and I brushed it off, but I found myself thinking about it later on. Why do we spend a third of our lives unconscious? Like somebody, explain sleep to me I. Understand why we need sleep. We all get it at. You've got to go and recharge the body, so you need to sleep, but this would be a great question for religious people. Like if we're intelligently designed, why don't we have? Solar panels. Or something else you know. Why don't we regenerate our energy constantly? So that one third of our lives is not spent unconscious. Now, having said that especially as a man in his fifties I. Love My sleep. I mean when you're a kid. They used to be like you need to go. Take a nap time to take a nap. No I. Don't WanNa take a nap. Yes, it is time to go. Take want to take a nap now anytime of day. You come to me new, say hey, let's take a nap I'm there I. AM so there you know, take the blackout curtains and pull them shot at two o'clock in the afternoon. Grab a soft pillow cod a lot, and let's just sleep Oh blissful, gentle, warm under the covers sleep. Oh, yeah, you don't have to talk me into my sleep I love it. I love, but if you think about it, a third of our lives, we spend not being able to participate in our lives. We are sleeping. Why have we not involved some sort of regenerative quality that allows us to use more hours in the day, and would we want that? Knowing how wonderful sleep really is? Oh, you know it feels good. Curl up under the covers and just. yeah. Would you wanNA live in a world without a bed time I don't think I. Would I I really don't. I still don't fully understand how microwaves cook my food. There's radiation. Water, particles or something involved. I've known who won't eat microwaved food because they're afraid of like radiation like uranium radiation. Well I know that's not real. List a different kind of radiating. That's taking place but I. don't really get it I just know. I put a baked potato in the microwave, and I clicked the baked potato button and four minutes later it comes out, and it's done by the way. Can you taste the difference between a baked potato that's made in the microwave and one that cooks for an hour in the oven, wrapped in aluminum foil because I can't. I went on facebook and I said, can you tell the difference between a baked baked potato and a microwaved baked potato and opinions were all over the place I can't tell the difference. Like, there's a sentimental quality to having the old school baked potato. Know you pull it out of the oven? It's taken so much time and care and love, and so maybe it means more to you. But. Can you really taste the difference? If you had a taste test side-by-side blind taste test oven microwave could really tell the difference I don't know. But back to the microwave, okay, how does the Microwave Cook our food? There's a website called. Explain that stuff. It's got little diagrams. It's a perfect website for a guy like me. It says. Inside this strong metal box there's a generator microwave generator. It's called a magnetron. The magnetron takes electricity from your power outlet, and it converts that electricity in into high powered radio waves. And had blasts those radio waves through the interior of the microwave, and bounces off the metal walls, so they're bouncing these waves, bouncing back and forth off the reflective metal walls of the inner compartment of the microwave. It's kind of like light bouncing off of a mirror. And when these microwaves reach the food, they don't just bounce off the food. They can pass right through it. They penetrate the food and as they travel through your food. It makes the molecules inside the food vibrate quickly. and. This vibration produces heats the faster. These molecules vibrate the more friction that means heat the hotter. The food becomes the more it cooks. These microwaves are passing energy onto the molecules in the food, and that's how it heats up. It actually cooks from the inside out which is different than the conventional oven, which has these elements that throw heat added from the outside cooking it from the outside in with a microwave. You're going right through the food. You're causing the molecules to get excited. They have friction against each other generating heat. Your food cooks from within. By the way the microwave was invented by guy named. Percy Spencer. He was trying to develop technology that used radio waves for airplanes and ships in poor weather and in darkness, so he was doing a whole other thing and according to the story, he had a chocolate bar in his pocket when he switched on the magnetron and all of a sudden, the chocolate bar melted because of the heat that the magnetron generated. So. He had this lightbulb moment. Hey, wait a minute. A magnetron might be used to cook. Food tried to non popcorn tried it on all kinds of food. Back in the fifties, he got a bunch of patents. He ended up with over one hundred and thirty different patents on the microwave, oven. My grandmother had one of the first microwave ovens back when they first became available to the purchasing public I was just a kid. I was really small, and the microwave was massive. Is this big stack the size of a small television? And it sat on this table. She had to dedicate a whole table to. It had a big cranked dial on the front of it. But man this was like you know. We had seen fire for the first time. It was like the coolest thing ever. I'll always remember that microwave oven at Grandma's house. Anyway. That's how we cook food in microwaves. While we're talking about microwaves, why can't you put metal in a microwave? You've got gotTA play the food. The fork is laying on the plate. You forget you toss it in there. You got sparks chaos, and I think it can even damage the microwave Bobbin. What's the problem? Wouldn't these radio waves? She's bounce off the metal like it's bouncing off the reflective sides of the box I don't understand. Let's find out. Why can't you put metal up POPs right up? Why can't you put metal in the microwave? This is from the kitchen dot com. The website says part of the problem with metals is that they are a lot more solid than food. As food gets hot. Water just converts steam. The energy gets released as the molecules inside a piece of aluminum foil. Heat Up. They don't have anywhere to go. The metal heats up very rapidly and will eventually catch on fire. Depending on the shape and the surface smoothness of whatever metal thing you put in the microwave, I don't know. Let's call it silverware. Okay, you put that in there. Some metal objects will reflect the microwaves back instead of absorbing them. So the way hits your metal object, it bounces off. It hits the walls at bounces off and hits the object again it bounces off back and forth back and forth so much so that the transmitter starts to overheat and you can damage the machine. Another problem is that metals are electrically conductive that say the object is a fork. It has pointy edges on it. Or you've got any metal object that has a pointy part of it. electrons will collect those edges, and enough of electrons build up. You can actually create an electrical arc, the jumps between the metal and the electromagnetic transmitter. This will make a mini lightning show inside your microwave. It's awesome and terrifying at the same time final note on microwaves. If, you've got an old dvd or CD in your collection something you know, you will probably throw away. Never use for any reason. Put it in the microwave. Now I don't actually you want to check this because I don't want to damage your microwave. But, if you WANNA, see a light show, take an old CD or DVD. Put it in the microwave hit start and about five seconds later you will get one hell of a show. You know what don't do it yourself. Let's play it safe. Go to Youtube and type in DVD microwave. In fact, let me see if I can find it to make sure I'm not leading you astray. Microwave a DVD. Oh, yeah, there it is, it pops right up. This particular video was called microwave DVD. Fun. And they've got it in slow motion so many map save the microwave in your own house. Go Watch somebody else do it. I thought it was awesome. Thank you so much for taking this journey with me. We may have to do this again. I enjoy these sort of general knowledge shows, or I guess vent shows just talking just talking you just about whatever happens to come up and you never know where that roads going gonNA. Take you right. I! Mean what are we covered to? Everything, from the prostate to microwaving DVD's to the royal family to the impending economic collapse of the United States I. Mean You just don't get this kind of variety in every show? I'm just saying. Be Safe Up. There I will see you back here next week on the thinking atheist podcast, take care. Thinking atheist on facebook and twitter for a complete. Of podcasting videos products like mugs and t shirts featuring thinking atheist logo blinks to atheist pages and resources and details on upcoming free thought events and conventions log onto our website. The thinking atheist dot com.

United States pain aspirin Aspirin facebook Headaches Harald Bluetooth Gorman Netflix Google Herbert Natalie Harry Shave Royal Family Norway Swelling Princess Diana
38. Cardiovascular Prevention: A Case Discussion by the Cardionerds

Cardionerds

51:31 min | 1 year ago

38. Cardiovascular Prevention: A Case Discussion by the Cardionerds

"Worldwide. Cardiovascular disease affects the lives of hundreds of millions dedicated cardio. nerds everywhere are working hard to fight this global epidemic. These are their stories. Welcome back Carter nerds. It's Dan. This is the first episode in a very important series of cardiovascular prevention. It is no secret that cardiovascular disease is the number one killer worldwide, the total impact on humanity is just staggering. A focus on prevention of cardiovascular disease is an impetus for every cardio nerd in this episode amid Korean Heather, and I walk through an illustrative case discussion and review our two plus four paradigm of cardiovascular prevention to fundamental principles of management and four steps in risk, stratification, and hey, everyone, it's summit. We are truly honored to be producing the series in collaboration with the American Society for Preventive Cardiology see the link. Link on the episode description to get onto their website. It's an incredible resource for learning networking and promoting the ideals of cardiovascular prevention and remember everyone we are an independent educational platform brought to you by trainees who simply love cardiology teaching. This podcast is not meant to be used for medical advice. The views expressed here do not necessarily reflect the opinions or policies of our employers. The hero of this episode I, E R patient gave us full consent to discuss the details of his journey, and we thank him so much for teaching all of us, and now a message from Dr. Ahmed Cara the president of the as PC. This is OBAMACARE PRESIDENT AMERICAN SOCIETY FOR PREVENT CARDIOLOGY PROFESSOR OF MEDICINE RECORD Ichi Southwest Medical Center I WanNa I. Think the cardinals podcast wouldn't amazing job. These folks do in really thankful to Dave elected to do this. Provincial series wrenching is so important so fundamental all that we do in cardiovascular medicine in the American. Psyche for Preventive Pretty Allergy were delighted to cosponsor this series to really promote what they do to share with all of you about the wonderful world of prevention in all great experts is GonNa Bring on his podcast. By way of a slight plug. We also want to tell you about the upcoming A. S.. P. C. Congress. This is like all other virtual congress now since we no longer can do face to face. This is happening on Saturday Sunday July, twenty three to twenty six. It's free for anyone to register strongly. WanNa get trainees register snaking earn more about the fueled prevention. Prevention here from some experts in fields who hope diminishing just in that and most importantly, we hope you get a lot out of the series, and if anybody wants to learn more about prevention, please reach out to myself or any one of these excellent speakers. They have coming up raw, pretty passionate about prevention, and we certainly want to others learn about it to. Korean huge congratulations on completing your general cardiology fellowships incredible accomplishment on that note we cardio. nerds want to offer our deepest congrats to every twenty twenty graduate out there, not being able to celebrate with the usual fanfare in no way diminishes your accomplishments truly cheers to you all heather, I'll definitely visits to that congrats, Dan Corinne and all the grads out there. Thanks Heather in Amish. I'm so excited to dive into advanced heart failure fellowship in two thousand and twenty one definitely looking forward to this upcoming research year on that note for all of. Of Our listeners rising to new and exciting roles this July. Congratulations. You can do this. You're stepping into. These new roles is especially poignant during these times of special need in the cove era while you work hard taking care of others, don't forget to take care of yourself. Speaking of Self Karen Sleep, Dan. How was your first emmy call of Gosh? Guys It was exhilarating, but at the same time it taught me a lot about what we're dealing with in cardiology and I can't believe I'm finally an interventional cardiology fellow the journey. Journey to get here has been legit. Amazing and I'm so thankful to my clinical research. Mentors Co fellows at amazing cards for all the support I've been fortunate enough to be involved in several percussionists events for my over the last couple of days, but I know that every and geographically beautiful artery at the end of case means that there is a patient who need support in terms of a holistic approach to tertiary prevention strategies Dan as a cat nerd myself about fell similarly you know cardiovascular disease, absolutely the number one killer globally and claimed. claimed the lives of nearly eighteen million souls in two, thousand, seventeen on the impact on society in terms of Welby or activity and economics is just unfathomable. Unfortunately, it's on the rise especially with the aging population and the obesity epidemic, the worldwide annual mortality increased by over twenty percent from two thousand, seven to two, thousand seventeen, and the prevalence increased by thirty percent in the same Tiberius. We can definitely do better make no mistake friends. Cardiovascular disease is one of our worst pandemics and we need to be all in to address this one. Those numbers are sobering and really mortifying. By the time, a patient has a deadly event from cardiovascular disease. There are probably been many missed opportunities. We can definitely do better earlier in other words I. Love for Dan to sleep there. All his stomach calls without any interruptions same page for sure heather. In fact, we had the opportunity to record interview. The Great Dr Leslie Show. Who is both? Interventional Anna preventative cardiologist. NERDS. Check out your feeds in the upcoming weeks. Wink, wink. Let's take opportunity to define some terms with regards the primary secondary and tertiary prevention. By the time a patient makes his or her way onto our cath table, assuming obstructive coronary artery diseases found and addressed, we are dealing with tertiary prevention. I E treatment of manifest disease with the goals of slowing or stopping disease progression in contrast, secondary prevention is identifying disease in very early stages before signs and. And symptoms to prevent clinical disease and bad outcomes like when we get Donald ultrasounds to screen for abdominal AORTIC aneurysms in men, ages sixty five to seventy, five with a history of smoking. The disease is there, but it's just early and still sub clinical secondary prevention is certainly better than tertiary prevention, but we can still do better with primary prevention, which is preventing the onset of disease in. In the first place we do this by reducing risk factors like canceling a patient to stop smoking, so they don't get that AAA in the first place, but guys, the real holy grail of prevention, rather the holy grail of all medicine is primordial prevention, which is preventing even the risk factors from developing in the first place, counseling a patient to stop smoking is essential, but isn't it better to? To prevent people from spoken to begin with, and this really gets us into the importance of population health, because all of these preventive strategies require collaboration among healthcare workers, public health officials policymakers end insures something I've certainly appreciate more now. That I've completed my first year of Master's at Hopkins Bloomberg School of Public Health, as physicians, it is our duty to emphasize every stage of prevention every patient. Every available opportunity for. Absolutely loving this discussion without a doubt, the best and most effective way to address the staggering party bathroom disease is prevention, prevention and Prevention, so let's review our HASHTAG leaders to plus four Preventive Paradigm to principles of management and four steps restriction. I described this approach in a recent review. I rode with Dr Leslie. Show one of our fabulous pulse. Check experts, Feta Lincoln the episode description. Without further ADO, the two principles of management are number. One emphasized lifestyle for everyone regardless of risk and number two escalate. Preventive measures increase worse because the greater the risk of more effective. These measures are on it so well. Put step one a focus on positive. If you will ever mood, agree that a healthy lifestyle is something that can be applied to everyone step to on the other hand. Hand. The escalation of prevention measures is something that must be tailored to the patient sitting across from you. If you have a twenty five year old, forty, five year old or a ninety five year, old patient, exercise and good diet will be advised to them all. However, you're not going to be putting all these patients on aspirin. High intensity statins because this will lead to more harm than good. So, it is crucial that before you embark on step to a legit risk, stratification must be done legit risk stratification could be nuanced, so we have to break down into four steps of stratification that can start broad and get down to the nitty gritty to customize each approach to your patient, so let's go over those four things right now, I, we start with a qualitative risk approximation. Identify risk factors start counseling and education. Every patient is different at risk. Prevention is not something that we can just eyeball the patient when they walk in the door. Second we step it up to quantitative risk estimation where we use a validated model to quantify a patient's future risk of cardiovascular disease. This will help put our patient into different buckets of risk, low, borderline, intermediate and high risk third. Third, if the risk estimate is in the middle ground, then we want to further personalise risk stratification, using risk enhancing factors that may not be included or captured in the traditional risk, calculating estimators and finally number four. If the path still remains unclear, activists consider getting a coronary artery calcium score to look for sub clinical disease, we will heavily delve into coronary calcium studies with a world leading expert. Expert Dr Mike Blah in an episode coming your way I, love this to plus four framework, so we emphasize a healthy lifestyle for everyone because we want everyone to be healthy, unstop additional preventative measures like Statin therapy, blood pressure management, maybe aspirin use based on their risk of future disease. We estimate risk using a four-part stepwise approach that's perfect, but remember one size does not fit all people have. have different values, perspectives and goals so throughout this to plus four approach we have to partner with our patients in a shared decision, making manner in order to guide management, education and counseling are must every step of the way. This is all very helpful, but friends. Let's get more concrete with an illustrative case. We can follow our patients health over years to demonstrate how to practice what we preach. The year is two thousand and four. Mark Zuckerberg founded facebook. Cassini becomes the first spacecraft to orbit Saturn and President Bill Clinton undergoes a four basil cabbage. This is also the year that our dear patient K.. A vibrant forty-six year old man presents to the clinic with sharp right Lord back, Pete, he's found to have a kidney stone, and effectively managed with IV fluids and payments has no pass, medical or surgical history and takes no medications. He has never smoked tobacco. Alcohol rarely and denies illicit drug use. He was born in Gujarat India. He is one healthy child and works as a hospital nuclear, Latin manager. He also threatening motel. His family history is notable for premature coronary artery disease, his father and two brothers being affected by age fifty two to fifty five years while I'm glad has back. Pain got better more discussion earlier, we should take every opportunity to baroque cardiovascular disease prevention, even during two visits like this after all healthy people tend not to see their doctors very often, so we really should make every encounter count. Our first principle of preventative management is to emphasize a healthy lifestyle for everyone regardless of risk in an ideal world. I would definitely WANNA. Council on this during this visit and I couldn't agree more. The chase light simple seven is an easy check wants to help. People improve their lifestyle. And the list goes like this number one managed by pressure to control cholesterol, three reduced blood sugar for get active five eat better, six lose weight and finally seven stop smoking, check, check, check check check and check the second principle of prevention management is to escalate preventive measures with increasing estimated risk, the higher the risk, the more effective these measures, so this gets us to the four steps of risk stratification that we mentioned earlier. Let's get practical and start with step number. One are qualitative risk approximation where we identify major risk factors and start counseling and education in an upcoming interview that we will air shortly. Shortly, we talked to master of prevention. Dr Roger Blumenthal and Spitfire several cases away, and you could just see how his mind works honing in on these qualitative risk assessments as we go along Korean. Tell us what we need to know about how to become inefficient qualitative risk, assessing beast, a journey of a thousand miles begins with a single step to get a sense of our patients future risk of a major asap D. event, our first step is to screen for major risk factors we know from the charts studied that nine risk factors account for ninety percent of the population attributable risk of an I and And those are smoking dyslipidemia, hypertension, diabetes, abdominal obesity, psychosocial factors, daily consumption of fruits and vegetables, regular alcohol consumption, regular physical activity, five of these risk factors account for half of CD mortality in the US and all of them are modifiable something that I am definitely excited about as a budding epidemiologist, those five risk factors, hypertension, hyper lipid, -demia, diabetes, obesity, and smoking their guidelines, for when and how often to screen for each of these, generally we should consider screening for major risk factors every four to six years. Suffice it to say that each of these is a silent killer and you won't know if A. A patient has them without specifically screaming for them. You don't want to wait until it's too late. That's absolutely right terrain all these really important to pay attention to every time you see a patient. Let's start with a few notes on tobacco use. We should always make it a point to reinforce that smoking for our nonsmokers, and to reiterate smoking sensation for our smokers, but first we need to Dick Little. Bit Hebron both smoking and smokeless tobacco increase the risk for AFC beauty and all cosmetology. Importantly secondhand smoke is also a critical risk factor. Think about it. The arteries don't care who's about the cigarette was. Also, unfortunate trend of e cigarettes, and vaping, highly concerning and lightly have adverse cardiovascular and pulmonary outcomes as well. We do know that there are reports of arrhythmias and hypertension maybe. Honestly. The whole tobacco industry is a travesty one third of coronary heart. Disease deaths are attributable to smoking an exposure to secondhand smoke. We just need to do better as a society at the patient level, counseling education and motivational interviewing our key, and should be activated at every available opportunity, but more than that pharmacotherapy can be very useful for some people including nicotine replacement. Radically appropriate referral to a specialist may be helpful for some people. On a population scale, though public-awareness touted policy and insurance based incentives are all really needed. Why am thankful that cardiologists like Kareem dedicated themselves to epidemiology on a broader skuas? Well, these are all such great points to summarize so far. Every visit is an opportunity to address cardiovascular prevention after all cardiovascular disease is the number one killer. We do this by following our two principles of preventative management. One promote healthy lifestyle on everyone and to escalate preventative management with increasing risk. We have four steps in estimating this risk beginning with the first screening for major risk factors to start the counseling and education well summarize hazard. Let's get back to our patient. The. Two Thousand and eight. America likes its first black president. Google launches the Chrome Web Browser and android operating system, and there is a global financial crisis. Two Thousand Eight is also the year that K now. Fifty years old comes to the clinic with atypical non exertions, chest discomfort, but given his extensive family history. He undergoes treadmill Echocardiogram, which is negative for Kenya at Manny seven percent predicted maximal heart rate. You chiefs, ten bets is Lipid. Panel shows a total cholesterol. One hundred ninety nine triglycerides at one fourteen hdl forty two ldl one thirty, four, his blood pressure during that visit is one twenty over seventy. We will get into risks ratifcation for obstructive coronary artery disease in a future discussion, but thankfully his stress test was negative. The fact that we are even considering stress testing in this patient lets us know that this is a great opportunity to properly stratified his future risk to guide preventive management before we do that I should emphasize that we only do this for primary prevention, patients who already have known ASEP D. are high risk by default and need aggressive management regardless with that. Let's walk through the four steps of risk stratification. Step. One and risk stratification is to identify major risk factors. Thankfully, he doesn't seem to have any of the major risk factors. At this point, it's a good thing. We counseled him on healthy lifestyle back in two thousand four and I would certainly reader if that now steph two is to quantify ten year. Suv De risk using a validated prediction model. We should use the model that best reflects our patients demographic in America. The recommended model is the ACC H.. A. Pooled Court equation described in two thousand thirteen. There are other models for different places like score DVD in most of Europe. J. B. S. Three in the U K China PA are in China. Generally speaking in America, we should use the pool cord equation to quantify risk individuals from. Forty to seventy five years of age without diabetes and with L., Cholesterol's ranging from seventy to one ninety milligrams per deciliter. This is because those with diabetes or Ldl over one, ninety are higher risk to begin with, and will warrants that in therapy a priori. So in our patient, who is in America, has an age between forty and seventy five. ldl between seventy and one ninety and dozen have diabetes. We can open up the risk calculator plug in the following variables race sex age total cholesterol HDL. Systolic blood pressure, anti hypertensive medication, use diabetes, status and smoking status. This will give us an estimated ten year risk of a major adverse cardiovascular event or mace, which will fall into one of four risk categories, the first low risk less than five percent, borderline risk at five to seven and a half percent, intermediate risk, seven and a half to twenty percent or high risk, greater than or equal to twenty percent. Okay let me plug that. In Age fifty did Lulu, Yada Yada Okay His, predicted tenure AFCD reschedule using the pool cohort equation, which won't be described for another seven years is three point two percent. He is in the low risk category. Correctomundo at three point two percent, our patient has low ten year risk, but let's review some important caveats to using the full court equation that explain why we need four steps to restrict vacation instead of just qualitative and quantitative steps that be executed so seamlessly to review the caveats number one the pull cord equation Derivation mission cohorts did not have ethnically diverse. And certainly didn't have an apple representation of South Asians who are at a particularly high risk which is going to be relevant for our patients from India. The Mesa order was more diverse. Number two. It treats diabetes binary variable without regard to or severity, obviously relevant in terms of risk doubts. Number three, it does not include family history, because in general including family history did not reclassify most patients, but clearly Kelly his also not binary, and you can imagine that a stronger dose of family history I e more family members that earlier age could be an important contributor to individuals risk. This is probably also relevant for our patient given his personal family history. Number four equations tend to over estimate risk those with predicted risk above ten percent higher socio economic status, which may be relevant for our educated business owner as well as those who are actively engaged in preventive care, which hopefully will be everybody. And, lastly number five, the record equations can underestimate risk in those lord status and those chronic inflammatory diseases, which is Wisconsin factor on it I. totally agree and reviewing these caveats really helps highlight some of the drawbacks to quantitative risk estimation. Let's also consider some specific patient groups, the young, the wise anti-racists, three examples to highlight this the young for those under forty years old a ten year time horizon is relatively short, so estimating thirty year or lifetime risk might be more meaningful guiding management. To the wise for those over seventy five years of age, the Pool Cord Equations may systematically guesstimate wrist in otherwise healthy person because of age alone and finally three the races, the pool court equation race field options are either. A white or African, American selecting the other category overestimate risk of people with East Asian and Hispanic white descent and underestimate risk in the South Asian population, which is so relevant to many patients that we take care of including our patient who's from India that's great review of the nuances of the pulled court equation specifically, but there are also pitfalls with risk models in general I know single individual actually has a ten percent risk of an event. This just reflects a population averaged risk based on risk factor variables often derived from population that may not perfectly reflect your particular patient. This brings up the importance of personalization. Secondly, we're basing these risk. Models on historic cohorts, whereas our contemporary patients in today's clinics are exposed to a whole different environment especially when it comes to newer and better therapies, this underscores the importance of updating models with time, thirdly, where estimating risk at a single time point without factoring in how long a patient was exposed to a particular risk factor or a clear understanding of how to use recalculation of risk over time after instituting targeted therapies. That's just. Just, not how these models were validated, guys those are a lot of caveats. The uncertainties of risk estimation only emphasizes the importance of patient centers, approach and shared decision making based on a patient's values, counseling patients and making treatment decisions are clear in the extremes when the patient is estimated to have lower high risk, but what is your approach in the grey zones of borderline or intermediate risk great points, the uncertainties of predictive models are only less certain. Homes this my friends is where we personalise risk estimation to our patient's unique self. Recall there are four steps were stratification. We've already done step one by denting major risk factors for qualitative approximation and step to by using prediction model to quantify risk. Let's keep going down. This prevention train steps who we and for all about personalized this approach step three is to identify risk enhancing actors and step forward is to selectively measure the coronary artery calcium scoring in patients. If you're still not sure. He's additional sets are particularly helpful for those in the borderline intermediate category, super excited deeper into personalization with Dr Alvin. Kara President of the American. Society of Cardiology so definitely. Stay tuned, folks. Let's put theory into practice. Consider a forty five year old woman of South Asian descent with a history of hypertension hyperloop, -demia Lupus, pre eclampsia to first degree relatives with premature ASCAP DE. The Pool Court equation estimates are having a ten year risk of six point five percent, which is borderline. Would you start a staten? If we only consider her quantified risk, the answer would be no. But. She has several risk enhancing factors which were introduced in the twenty eighteen cholesterol guidelines. Let's review these unique risk enhancing factors family history of premature Asap de ldl. Cholesterol greater than regal to one sixty or non hdl greater regal to one ninety CK, CKD, Metabolic Syndrome, pre ECLAMPSIA, premature menopause, inflammatory diseases south. Asian ancestry or certain biomarkers that include triglycerides LP little a high sensitivity, syrupy April be an ankle break. You'll index in general the presence of risk enhancing factors, fevers initiation of STATIN therapy in those with a borderline risk and intensification of Statin therapy in those with an intermediate risk Korean. Your hypothetical patient has several risk-enhancing factors South Asian descent, chronic inflammatory disease, lupus, adverse pregnancy outcome pre ECLAMPSIA. A family history of premature artery disease, so even though the pool cohort equation landed her in a borderline category. I would probably start a staten. Heather. That's perfect. That's exactly what I would do as well. This case really highlights the need to individualize your patient and not just plug in some numbers into a calculator and spit out a recommendation, and as for the prediction models are some important caveats here as well. We have little guidance about the relative weight of different risk factors, and the greeted hazards of more severe canceling backers in practice, we still tend to use them as a binary variable are the present or absent. Clearly the reality must be more complicated and I'm sure the guidelines will continue to get worse. As more data. That's a great lead into step four, considering all these pitfalls and grey zones, it's no wonder that after flawlessly applying steps one through three, the patient and doctor might still be left with uncertainties of how to proceed, but we can take advantage of the fact that most forms of atherosclerotic disease develops over time as sub, clinical or AKA, the silent killer recall that atherosclerosis has quite complex pather biology with along and inland progressive phase before culminate in the first heart events in the form of a stroke, heart, attack or leg ischemia. Have other really great validated non invasive tests that can scout out for sub clinical athletes, grosses, and uh, towards a more aggressive preventative recommendation. So! Into, thickness by vascular ultrasound and ankle break indices are great examples of this fight. The one best test with the best data and advocated by the guidelines is measuring patient's coronary artery. Calcium score AKA THE CAC. Patients essentially undergo a dry chessy. T and the extent of coronary calcification is quantified. Pods do we. Is it actually people use the word, Caq? It's not see a sea or Is that like some. It just kind of weird to me now. So I'd Hopkins, Caq what? I don't think that people use against much, but now they will episode. We should be. We could probably say it out. It's a good point. Has that in our vernacular? We use the word caq lot. It's kind of a weird sounding word. Know what you guys think it's. DuNNo. I also think it is I do I really do. You we could coordinate calcification or You want to see WHO's ACC. We're going to be saying hundred times. I can say see A. C.. Lingerie I think he says caq but. She says. Because! Heather for the record I totally agree with you. It's a weird sound that word, but they usually overheard. It's like. This. We tencent coronary calcium every time. Much? Scoring sounds sounds A. Lot of continence. were. Slave except F Y CAC is a very interesting sounding word, but we'll just use it for the sake of brevity going forward. Love it again as Janet mentioned earlier. We're going to be doing a deep dive into tax. Scoring with Dr Michael Blah True Cardio nerds expert in the area, but for practical purposes. Here's CAC scoring in six pearls one. Kakov provides the greatest net reclassification benefit in those at intermediate ten year risk. To CAC scoring is low yield in those at the low or high on your risk cat scoring may be useful for those at borderline five to seven and a half percent ten year risk especially in the presence of risk enhancing factors like our hypothetical patient, a cat score of zero portends a low near term, future risk and set in therapy may be deferred. A cackle, greater than Regal, two, hundred, or greater than or equal to the seventy fifth percentile for sex, ethnicity indicates underlying atherosclerosis substantial ASC do rest and favor statin initiation, and lastly an intermediate CAC score of one to ninety nine or less than the seventy fifth percentile visa, intermediate risk and sat there. Be should be considered especially for young patients who have. Have more time for progression of sub clinical atherosclerosis for the right patient. Measuring score can really be super helpful. The risks are minimal. It generally is low cost and comes with low radiation over ten percent of incidental findings, but usually these findings turn out to be benign, but let's keep going with the theme and cover some of the caveats with CAC scoring. Number One cat scores do not decrease with time and so rechecking score after statin initiation is not recommended. Second CAC very well can increase with time as atherosclerosis progresses, and so if statin therapy is deferred due to zero score, re stratification after a period of time like five years is reasonable. Third attack of zero should not be used to defer statins in high risk conditions such as diabetes, smoking and a family history of premature coronary artery disease as our. Our patient has and finally fourth can't. Scoring is validated for risk estimation in asymmetric patients and should not be used to triage symptomatic presentations to highlight the importance of this. Just remember the cat scoring is the amount of calcium associated or as part of the coronary arteries, but it doesn't tell you anything about the looming of the coronary arteries, so the way I explain this to patients is if I have a coronary artery literally lying in front of me. Me and sprinkled on sugar like a doughnut. You know like those sugary doughnuts, and that's all over the artery, but it's kind of on the outside of the artery that will come up as an let's say the sugary during it as calcium that'll come up as high calcium on the calcium score, but I've actually done anything to the lumine of the coronary artery, and so it doesn't tell me anything about the obstructive nature of that coronary artery so calcium. Calcium is really a marker of sub clinical Atherosclerosis, rather than a marker of obstructive coronary artery disease, and that difference is nuanced, but very important to make, but I will say the caveat is sometimes the patient will be referred to me with a ridiculously high coronary calcium that was done a screening, but they're totally asymptomatic and the next steps to handle. That could be a little bit nuanced and complicated, and we'll save that for discussion with Dr Blah. Point Dan. Thanks much for our listeners a gotTa. Give you a disclaimer that the cardinals by no weeds advocates, sugary doughnuts, especially as part of our series in summary The selected use. CAC scoring can be a very powerful tool. Imagine a thirty eight year old with a strong family history of early coronary artery disease at a healthy, vibrant, seventy eight year old with no medical history or medical problems. Whatsoever, the score may be really helpful to out classified risk for the thirty eight year old for doubt classify risk in the seventy year old. Because steps, one-two-three may have feel them both. There are risk estimation tools which incorporate traditional respect. Chris and a tax court to quantify ten risk life Mason score, or the s return score I love it CAC scoring, which sounds like a really weird word does sound super helpful in the right context in my clinic I got a cat score when I'm still not sure what to do after steps one two three of risk stratification, generally when the patient is in the grey zone of estimated ten year risk of five to twenty percent. Tax Scores have helped me canceled patients while reinforcing the importance of preventative measures like lifestyle and medications. Picture is really worth a thousand words. That's absolutely right, and beyond restriction non zero package can be very motivating with that. Let's get back to our patient. To Year is not two thousand fifteen FUCHSIA president. Trump announced his bid for presidency China built several islands dispute South China Sea. And the black lives matter movement founded in two thousand thirteen is reborn with a tragic fatal shooting of Walter, Scott and Frankie Gray, revealing the fragile fractures and the foundation our society. It was also this year. That K is seen in clinic for polio, Paulie Diptheria and blurred vision blood pressure in the clinic is one hundred fifty to over one or two. Is Weight is hundred sixty six pounds BMI of twenty nine laps reveal an HP ONC- of eleven point one, and his urinalysis is positive for micro unirea this spring back to step one of risk stratification where we identify major risk factors for qualitative risk approximation as a bedrock for patient, counseling and education. Your patient is now presenting with classic symptoms of overt. Diabetes Stage to hypertension and obesity like atherosclerosis. The onset of major risk factors is also often indolent over time highlighting the importance of screening. Ideally. We diagnose these early a dramatic stages to get a head start on management and risk qualification, the longer a patient has poorly controlled diabetes and hypertension the worst their outlook. Now that he has diabetes, we can get off of the risk stratification train remember we do not use the pool court equation to quantify risk if patients have established AFC, diabetes or LDL greater than one ninety since he has diabetes, we already know that he warns at least a moderate intensity statin patients with diabetes. Important risk enhancers should be on a high intensity staten risk enhancers. Diabetics include greater than ten. Ten Years Duration of type, two diabetes and Greater Than Twenty Years Duration of type, one diabetes greater than or equal to thirty micrograms albumin per milligram, chatting and egfr less than sixty retinopathy neuropathy API less than point nine in those with multiple Asap de risk factors like in our patient, we should start a high intensity staten with the goal of lowering ldl see by at least fifty percent in addition to starting a high intensity status. We need to aggressively manage his modifiable risk factors in his case, diabetes and hypertension. Both of which are Putin risk factors for a seb deep. Just to underline this very important point, a twenty millimeter mercury higher SBP intend milimeter mercury higher diastolic blood pressure were each associated with a doubling the risk of death from stroke, heart, disease or other vascular disease for our patient within a one C of greater than eleven, percent and stage to hypertension. We really need to jump in on this double stat. Thankfully in just a few episodes away will be joined by Cardio. NERDS experts Dr Dennis Brumer, who is double boarded in endocrinology cardiology to really dive deep into diabetes. and Dr, Luke laughing. A preventive cardiologists focus on hypertension to further. Expand our knowledge in this area, so stay tuned. Okay, so we would definitely start a staten at this point and double down on managing diabetes and hypertension, but what about aspirin for primary prophylaxis? Before the disease developed after the publication of numerous large trials doesn eighteen. We saw a paradigm shift away from primary perplexes aspirin the arrive trials sought detests aspirin in those with ten year ASC De Risk of ten to twenty percent, but the actual risk was lower at about eight percent in these patients. There was no benefit but a twofold increase in gastrointestinal bleeding. The essential studied aspirin use in patients with diabetes and found a modest benefit counterbalanced by modest harm. You would need to treat fifty nine patients over ten years to prevent one adverse cardiovascular event, but at the same time one in seventy seven patients would be harmed by a major bleed. The retrial studied aspirin use in the elderly over seventy years old. It was stopped early due to futility given no difference in Mesa outcomes, but a significant increase in bleeding with the number needed to harm a forty two over ten years. These trials really blunted enthusiasm for aspirin use in a primary prevention population, but are there patients who may benefit Craig points, heather, and really a phenomenal recap. Those trials one of the main reasons these trials failed to show meaningful benefit is probably and hopefully that the contemporary population is just different from the days of your with better background, medical management, greater awareness of healthy lifestyles consistent with. With us, he event rates were lower than predicted these files, but look none of them truly specifically stayed up high tension with a high predicted tenure risk that was able arrived trial, but the enroll published ended up having a lower predicted risks, primary preventive brin decently has less today than I didn't twenty seventeen, but until we have where data are certain patients, who may very will benefit. Some health guidelines one load aspirin might be considered those with the high ESCB risk or those at borderline or intermediate risk, but with important risk factors importantly are not increased risk for bleeding. To low DOSE ASPIRIN SHOULD NOT BE administered on basis for primary prevention of SUV among adults over seventy years H. Three low dose, ASPIRIN SHOULD NOT BE administered for primary prevention among adults of any age who are at increased risk for bleeding. And finally, finding sub clinical atherosclerosis by category may help identify suitable patients for prevention aspirin remember the two foundational principles of preventative management. The first is to promote a healthy lifestyle everyone regardless of their risk and second is to escalate are targeted preventive management with increasing risk. Promoting a healthy lifestyle is as important now as it was back in two, thousand and four. Diet, exercise and weight loss are particularly helpful for combating diabetes and hypertension. The Dash Sodium study showed the additive efficacy of both Dash Diet and salt restriction on improving blood pressure, importantly, the higher blood pressure, the more the advocacy and the Mediterranean. Diet showed improved macy's outcomes in the MED study with modest improvements in blood pressure. There is also a meta-analysis level data for the anti hypertensive effects of plant based diets, whichever diet higher potassium intake is helpful, and when it comes to weight loss, individuals abusively should be recommended a comprehensive lifestyle program that focuses on low calorie intake piece by five hundred calories or Or eight hundred to fifteen hundred calories per day diet as well as high levels of physical activity, two to three hundred minutes per week for most office, setting realistic goals vitally important. If we expect them to reach for the stars and may fall short, it can be very demoralizing rather what I find to be incredibly motivating. Is that just a five percent? Weight loss can make a world of difference with improvements in blood, pressure, ldl, cholesterol, triglycerides and glucose levels as well as delaying the development of type, two diabetes melody, so giving them. This sort of realistic goal can be right practical for some patients. Patients, it's easier to swallow. This is particularly important for a patient whose BMI is twenty nine, categorizing him as overweight, just shy of obesity, the two dozen Thirteen Ha acc obesity guidelines recommended any of the fifteen evidence based diets with reduced calorie intake for total calorie deficit. They also recommended referral to a registered Dietitian. A team approach is a must hear. Generally, we should recommend that patients reduce diets that are high in sugar and other simple carbohydrates, refined grains, trans, fat, saturated, fat, sodium, red meat, especially processed meat while at the same time, encouraging an evidence based Diet like Mediterranean type diet high in vegetables. Vegetables fruits nuts whole grains, vegetables, Orlean animal proteins like fish and vegetable fiber portion control regardless of particular diet is important to to manage caloric total caloric intake. Also physical activity is a potent anti atherosclerotic. There's a strong inverse relationship between time spent doing moderate to vigorous physical activity and incidents of e outcomes and mortality, despite this about fifty percent of US adults do not engage in even the minimum recommendations. We need to encourage our patients to engage in at least one hundred fifty minutes a week of moderate intensity, exercise or seventy five minutes a week of vigorous intensity, physical activity, including resistance exercise. There is no substitute to diet and exercise for a healthy lifestyle and losing weight, but not uncommonly we need patients who continue to live with unhealthy weight despite their best efforts, these are opportunities to re-engage in motivational interviewing identifying hurdles like access related issues, education, and even looking for secondary causes, but after going through this checklist, we may still need to activate a junked measures like pharmacotherapy or metabolic surgery. Those tools are probably very under utilized pharmacotherapy for weight loss should be considered for BMI greater than or equal to thirty or greater than. Than requested twenty-seven With Co. Morbid conditions referral for metabolic surgery should be considered for BMI greater than equal to forty or greater than equal to thirty five with comber entity. Stay tuned for a pulse check to learn more about the approach to obesity with my mentor doom lay with our patients, a onc- and stage to hypertension. He will also need pharmacotherapy for his diabetes hypertension in addition to lifestyle measures, really looking forward to our upcoming diabetes hypertension episodes to dive deeper into these topics. Let's get back to our patient K., A. After losing thirty pounds, his agency drops to five point six on Metformin. and. Blood pressure is controlled on single agent therapy with justice hearten. Let's forward to the year. Two Thousand Eighteen ereck number women are elected into public office, including the first, Muslim and first native American women to join Congress Right Cavanaugh joins the Supreme Court. And Toys Russ liquidators US stores. Oh my guy. Win Toys R. US was liquidated myself and my millennial comrades really mourn a loss. Dan Don't even get me started the thought that my children will not know the joys. What Toys R. US agitate? It just saddens be so much. Totally But you know this is also a significant year far patient. In Two Thousand Eighteen C, K and the U D he's had three days of EPA, gastric pardoning discomfort radiating to the right arm on that day. He's had unremitting symptoms since three am. Issue reveal science, Cardiac and infra posters semi. Pattern! He's taken for immersion coronary angiogram with shows severe Joel epilepsies involved in the mid led oem one and made RCA. He undergoes successful. To the RCN Owen one emergency during the index procedure as well as staged intervention to the led. ECHO, shows preserve by intrigue function inferior while woosnam melodies. Thankfully. He's doing quite well clinically and is discharged on dual antiplatelet therapy. Density Stab Bell Our town. Our Federal Metformin as well as plans to begin cardiac, we have. I'm so happy that he did well our patients. History really shows us that risk factors are real, but they can remain quiescent in the background simmering underneath the surface until it's too late, because patients with risk factors generally feel fine in the moment and problems. Don't come until years later. It is really hard to motivate our patients and ourselves to improve lifestyle and manage modifiable risk factors to reduce future risk. Thankfully, our patient did. Everything he could with impressive weight loss and controlling his hypertension and diabetes like any other time in his life. The two foundational principles are as true as ever when need to keep promoting a healthy lifestyle. Cardiac Rehab will be a key part of his exercise plan moving forward. In addition, we need to pay special attention to his emotional wellbeing. A heart attack is a major event with important implications on self perception of vitality mortality couldn't agree more, and the second principle tells us to escalate target preventative measures with increasing risk. Now that we know, he has established air CD in addition to lifestyle. He will need anti platelet therapy, high intensity, stanton and possible non staten adjuncts to get his ldl to a goal of less than seventy, in addition to aggressive control of his diabetes and hypertension, known prevention series is complete without a super deep dive into the Greasy World of lipids and we'll get to. To that with Dr Sancha Dr Anne Marie, Navarre, our colleagues at Duke Medical. Center is now that you're twenty twenty. The world is ravaged by the COVID nineteen pandemic. The Cardi hurts win the hearts for global audience, the death of George Floyd. We Awakens the Black Lives Matter Movement with international protests in June of this year I personally spent time in the clinic nuclear lab, whereas we call it hot lab to become a nuclear authorized user as stepping stone to becoming nuclear borden, it is here that I met Our Beloved Patient K Aka conduct amine. Cut Up is the manager of a nuclear lab. Who for the following month taught me everything I need to know about radio isotopes nuclear decay handling nuclear raced mixing technician for Nuclear Scans and everything else need to become verified authorized user. But anyone who spent five minutes with knows he's so much more than that. Joking around with him in the lab, enjoying historians over coffee and taking field trips throughout the hospitals and other parts I grew to admire antidote coke. As. He taught me about finance politics, and like general, he also shared his journey as a patient as a learn more about him I became so inspired by his commitment to a healthy lifestyle. I just knew we had to get audience on the cardinal's platform, so that everyone can enjoy learning from his story the same way I did every day of the past month one day, a colleague waivers into the lounge and Kinda took one look at the nutrition facts, and put that container down without any hesitation kind of course consent to share the details of historic with you. So to Kinda coming and all the patients brought us here. We Carter's thank you from the bottom of our hearts. Your stories make our hearts flutter. That was wonderful I'm. It cannot really sounds like an incredible person. I'm really excited to hear his perspective in a separate episode for our audience. Let's view the PM or points of maximum impulse for SUV CBD prevention just follow our cards to plus four paradigm, the to foundational principles of prevention are one promote a healthy lifestyle regardless of risk to escalate preventive therapy with. With increasing predicted risk, you therefore need to predict risk. The four steps of risk stratification are one qualitative risk approximation for identifying risk factors to quantitative risk estimation, using a validated model that fits your patient population three factor in risk enhancing factors. If the patient remains in a grey zone after steps, one and two and fourth, selectively measure coronary artery, calcium, scores or CAC score. If the path forward still remains unclear, remember patient education counseling and shared decision. Making is absolutely essential for every step of the way. Hi I'm the patient, connect me that you just heard about on the podcast. Just want to take this opportunity to thank. By Physicians Dr J. Were, and all the FELLAS also ducked to LS and Jonathan. White. Who get the standing for me? And all? My fellows that they're here. I could go through all the nations. But I might forget someone so they might get upset someone to say. All the fellows who are here that gave to Nick I love them. They're great people. And also the twins were deemed they merged city. They did a good job of flight taking me over here. A healing me down to the main campus, so I really wanted to thank everyone for taking such good care of me.

diabetes Prevention Dan Corinne hypertension staten president ASPIRIN Heather aspirin CAC Carter obesity American Society for Preventiv Dr Mike Blah US China AFC P. C. Congress