19 Burst results for "Zonta"

"zonta" Discussed on Mythology

Mythology

02:02 min | 1 year ago

"zonta" Discussed on Mythology

"There's something to note all myths have many versions and variations for this episode we've selected those we feel the most dramatic and entertaining and supplement did them with additional research into the LAKOTA nations traditions because mythology comes from oral tradition there's a wide variety across sources all night and all their combined efforts to erect even Zonta who was pregnant had helped where she could despite a key how's insistence that she not strain herself she reflexively place to hand on her swollen stomach as she thought of their child dude arrive any day she had not had the heart to tell a key Chautauqua that it had been days since she had felt the baby move onto glanced up at the dark storm clouds gathering overhead she wondered what her husband was seeing now the Keita had disappeared into the medical teepee moments ago with chief Standing Hollow Horn and the strange maiden the maiden she had arrived from across the plain dark hair whipping in the wind feet hovering several inches above the ground a key to Utah said she was we'll con- a Holy Spirit it and perhaps he was right all the LAKOTA had been overcome with awe at the sight of her and had dropped to their knees in supplication but as the woman's sharp is fell on Zonta she had not felt aw or wonder only fear and dread.

Zonta Utah
"zonta" Discussed on WCBM 680 AM

WCBM 680 AM

02:16 min | 2 years ago

"zonta" Discussed on WCBM 680 AM

"That'll be missing is that they will not have. The investigative powers of the department of Justice. I e the FBI propelling them and less they can find some rogue agents help them, but it's still going to be. Rogue. So I think the smear campaign on Trump will never stop the attempt to link him too, bad actors isn't never going to stop. But there won't be a new Muller type investigation to look into Trump and WikiLeaks. But again, they don't need that folks. The thing that you can't forget, and I'm sure you won't is especially now that they have suffered this deep humiliation. Now that there little scared. Remember what this investigation, quote unquote, was do not ever forget this. It was not an investigation. There was never any collusion. What this was in fact to state this. I'm gonna go back to what really was the origin of all this the origin of all of this was to exonerate Hillary Clinton. Hillary Clinton had violated numerous federal laws with her server are illegal. Private Email server with which and on which she was trafficking in classified data. In addition. There was the Clinton foundation she was selling influence to foreign buyers. On the come under the assumption. She was going to be president. She was raking in money. She and her husband were raking in money on the premise that they were going to be back in the White House and could therefore repay that money in policy ways. Or who knows however which way? Hillary Clinton had to be democrat nominee. They have to cleanse her. They had to exonerate her of all criminal activity. They had to not just insulated and doing Zonta Reiter and Komi did that on July fifth two thousand sixteen with that press conference..

Hillary Clinton Trump department of Justice FBI Zonta Reiter Muller White House Komi WikiLeaks
"zonta" Discussed on Around the Horn

Around the Horn

02:27 min | 2 years ago

"zonta" Discussed on Around the Horn

"No-one exports is going to save the world will maybe I do. Maybe sports can't be the conversation where where this goes on Sarah Spain, I want to get you to consider all of this. What you just heard from all the Zonta article the conversation that basketball's having women's basketball specifically. Yeah. I wanna start off by saying, I don't usually agree with tomatoes, and I don't necessarily agree with saying flat out. I'm not hiring anymore men because I think that if it happens with other groups of people at can be problematic that being said, the article was essentially what aboutism, and it said, we'll no let's not deal with the issue of women representation in college sports because we should be dealing with women of color. We should be dealing with LGBTQ coaches. Those are issues that have been a need to continue to be addressed. But not for the sake of ignoring the larger issue that pre title nine ninety percent of the people coaching women's sports in college where women now it's forty one percent. Those jobs have made more money. They are higher profile and men are coming in and taking them. Now. That's fine. You wanna hire the most qualified, but if it's resulting in looking like the rest of the world where everything is run by many, even when it's to lead young women. It doesn't make sense. So if her argument is based on that, then it's a good one. Now, never hiring a man might be an issue. That's taking it too far. But I think for the most part she speaks for a lot of people in this Smith. Zero issue from grind say well said, Sarah, there's one woman, and she's an assistant at the university of Maine, coaching and men's college basketball. So if men's college basketball starts to hire women, then muffing McGraw can back off of her statement of I'm not hiring men. There's no need for her to hire men because men have all the jobs to begin with to Sarah's point a muffins point. I had issue with the column though. Because like, well, if somebody said, I'm not hearing anybody who's pregnant or anybody who's disabled, well, that's such a false equivalent because it's not like people who are who are disabled arm positions of power is not the needs to be some kind of balance. If you did it by this double standard, it's a double standard. Put a sake of all setting unin Justice has gone off far too long. Tara VanDerveer at Stanford has never had a woman understaffed since nineteen eighty five so just because Muffin has taken this opportunity and applaud her for doing so for using their platform to draw attention to this issue. There's no reason for us to start looking at like, oh my God. Well, all the. Mid who aligned up to college basketball jobs and women's college basketball now somehow being deprived to best. She's got to do it this way because she doesn't are women and women don't hire women. Unfortunately, the fact of the matter is who will because men are doing it enough right guy. Sola?.

basketball Sarah Spain Zonta article Muffin McGraw Tara VanDerveer Smith university of Maine Stanford nine ninety percent forty one percent
Pope Replaces Chilean Cardinal Accused of Sexual Abuse Cover-Up

America's Truckin' Network

00:43 sec | 2 years ago

Pope Replaces Chilean Cardinal Accused of Sexual Abuse Cover-Up

"Eva. Pilgrim after refusing to resign. Refusing the resignation rather a French cardinal found guilty of covering up sex abuse. Pope Francis accepts the resignation of a Chilean cardinal for his handling of abusing priests. Pope Francis has accepted the resignation of Chilean cardinal Ricardo Zonta of Santiago. He has faced widespread criticism for his handling of cases of clerical sexual abuse in his country. The cardinals is the eighth resignation. Pope Francis has accepted after almost every Bishop in Chile offered to step down in may last year. That was after a three day meeting at the Vatican to discuss the clerical sex abuse

Pope Francis Ricardo Zonta Cardinals Eva. Pilgrim Santiago Chile Three Day
"zonta" Discussed on Izzy and Spain

Izzy and Spain

02:47 min | 2 years ago

"zonta" Discussed on Izzy and Spain

"He's going out now and traded for two players who can who could walk the summer unrestricted free agents and the planet. Philadelphia's to resign both of them into financial financially. You know, they see a way that they can have those two than obviously NBA contract is he's in the middle of max steel, and Ben Simmons Zonta way to Amax the oil that he can negotiate next year. So it does give them some insurance. If one of the players did leave it gives you another wing you have three instead of four but ownership in Philly sees this as a window that they want to go for it. Yeah. And I think if you are in the east right now, you should because there is no clear winner. There's no clear leader for me inexplicably. Despite all past telling me that there is something deeply ingrained within the very spirit of the raptors that will cause them to fail. I believe that new coach new star. Is enough. But I also believed last year. I know I know new star new coach no LeBron should be enough for whatever reason, my gut still has the raptors as favourite when they're all healthy and playing together, I think they can be the best. The Celtics roster has vastly underperformed for the amount of talent on it. When they're together if they get it together. They're also a compelling squad. I think the Sixers roster talent wise is as as good is approaching what the Celtics have, and they may be better able to put it together. Because they haven't struggled the way the Celtics have also the problem is those other two teams have kind of forgot the bucks. No, we'll get into the bugs. But those those other two teams have kind of dealt with their difficulties now for fifty games. Whereas Philadelphia's now throwing another couple of pieces in there that guys have to learn to play with and I'll be honest with you. I heard you talking about signing people at the end of next year. I'm not I'm not one hundred percent that Ben Simmons. And Joel Embiid are the match made in heaven that everybody thinks they are. And we know they aren't a match made in friendship heaven question. Are you saying basketball or? Heaven in basketball, heaven, Ben Simmons is a talented player. He's very very talented players all star. He's a terrific player. You know, all the LeBron comps. We obviously know now that they shouldn't have been LeBron confidence. He's player, but I wouldn't be surprised if bin Simmons a year from now if they if they stumble a little bit in the playoffs and live up to expectations of Vince Emmons is being talked about the same way ending Davidson's right now. Good news is we'll have KENDALL Jenner to blame. And we always have to have occurred to ask you play Jenner or anytime. There's a Qadesh family member we like to blame that spin the wheel Rob's coming back say round come on out your turn robs ruined sue bird. Somehow ESPN radio is presented by progressive insurance making it easy to bundle your home and car insurance super good for that..

Ben Simmons raptors Ben Simmons Zonta Celtics LeBron Philadelphia KENDALL Jenner NBA basketball Amax Philly ESPN Sixers Vince Emmons Joel Embiid Davidson one hundred percent
"zonta" Discussed on Pet Life Radio

Pet Life Radio

02:53 min | 2 years ago

"zonta" Discussed on Pet Life Radio

"Want welcome to groomer humor on pet. Life radio. We are your host. I'm Rudy the along with my son, Anthony Ray, and we're so excited about this show today because we're going to be talking about food, and we love talking about food. Right. And we love eating food to obviously little too much. I think. Yeah. In particular, we're gonna be talking about pet food. But man, what a great topic. I mean, it's been a really really fun summer for me. I've eaten so much pizza and sausage parm. And all that good stuff. And how about you, man? What's your steady diet these days in lasagna? It's just kind of in general. Lasagna with a lot of sauce on it. Yeah. That's it. Not even really drinking water a whole lot. Just just Zonta just Sonya. Luncheonette dinner lasagna and call for breakfast. I'll have a cold peace lasagna. Yeah. I don't really like like hot food that much for lunch. I'll probably have another cold hunk of lasagna. Title in with with a third Donya or two for dinner. I had an order of mozzarella sticks at the diner the day. But it did have like a healthy overtone 'cause they laid it on that of lettuce, y'all. Yeah. Yeah. Yeah. I, but I didn't eat the lettuce. Of course. Not. But but if if felt like I was doing something healthy though, because I saw the Edison. I like look at this. You know, what it is anytime? There's something green on the plea. It makes you feel better. Right. Even if it's not good. Just some on the plate or even if you don't need a lot of times like I'll have a big bowl of mashed potatoes. You know, and and, you know, they'll be some they'll be some string beans, and there's broccoli with a little corn in it a little corn. And you know, and then you just kind of work around the colors and just go for the mashed potatoes. You know, whatever as long as healthy stuff. Is there for me? It's just it's a placebo thing. I feel like I did I'm doing something. Good. I love that. We definitely we treat our dogs better than we treat ourselves. And I think that's gonna be the the point of this show today because we have we have a really great guest coming on Rinaldo web from pet flea and men this guy has designed some super super designer healthy food for our dogs. I think I want to indulge in it. I might might take a few scoops. Do they I wonder if they have lasagna? Maybe maybe come out with lasagna flavored who knows? You know, it just to make it easier on him if they just just cheese. Anything cheese really is works for me. But yeah, that's definitely the the theme today show for sure none of that. Unhealthy stuff coming into our dogs lives. Okay. And that is the purpose of this show. We are going to be talking about this amazing food that.

Anthony Ray Rudy Edison Zonta Rinaldo
"zonta" Discussed on Stuff To Blow Your Mind

Stuff To Blow Your Mind

02:24 min | 2 years ago

"zonta" Discussed on Stuff To Blow Your Mind

"I feel like Pinto is setting up this model as like as like a counterpoint to the idea of of what spirit Gonzaga discovered, but it seems actually to me kind of in line with what they discover like the idea that our consciousness is very mysterious. I mean, spearing Zonta would say that despite being able to produce these behaviors that look from the outside like as if they're from two different people the experience of the patient as they've always reported is that they feel like a normal person. Nothing seems to have changed them right at I think in both cases, though, it just end up in this weird conundrum almost this paradox. This idea that the single person we feel that we are is in some ways to and in these cases. Where we see evidence of or seemed to see to evidence of what you could call two minds within one brain. They're still functioning as one they are still one. And so yeah, the paradox of that which is one seems to and that which is to seem as one or more than two. Yeah. I mean, the we've got the two hemispheres of the brain. But remember, the hemisphere is each full of you know, modules and elect their full of millions of neurons and they're working in different networks and modules to accomplish different goals. And so I think one of the lessons is definitely different parts of the brain can be h-have and regenerate behaviors independently. And somehow you are here, and you end up thinking, I am a person there's one of me, but there's a lot of different independent stuff going on inside. Whatever makes you. Yeah. I come back to that hunter S. Thompson warns Yvonne, quote, your whole different person when you're scared and in because. Then some to some extent is we've discussed you are a different person, or at least a different version of the person. So yeah, how many how many us are there? Really? Well, I think we can explore this more in the second episode. But this really should give us some questions to think about questions about whether our idea of a person or a self is really an accurate understanding of what brains are like, or is it just a is it just a convenient illusion. And that this stuff to blow your mind or minds. If you will. Hey, if you.

Pinto Zonta hunter S. Thompson Yvonne
"zonta" Discussed on Stuff To Blow Your Mind

Stuff To Blow Your Mind

03:52 min | 2 years ago

"zonta" Discussed on Stuff To Blow Your Mind

"But then Gonzaga has him closed his eyes and draw with his left hand, which is controlled mostly by the right, hemisphere and his left hand draws a pan. Oh, wow. Again, legitimate chills. And of course, after he draws it. And looks at it with both eyes. He can say, yeah, I saw a pan. But the part of his brain that talks didn't seem to know he'd seen a pan until after his left hand, drew it. Another type of experiment carried out you. Take a split, brain patient and simultaneously show. Two different pictures on the to to the two different hemispheres, you show a hammer to the left hemisphere, and you show a sought to the right hemisphere. And you ask what did you see? Of course, the speaking part of the brain says a hammer the person says I saw hammer, but then when asked to draw with the left hand, the patient draws a saw and you ask them why did you do that? And the patient in this one case the case of Joe says, I don't know knowing other cases like this versions of this test. Sometimes the speaking part of the brain will not just say, I don't know. But we'll actually seem to make up stories about why their brain produced a certain output that the left part of the brain. The speaking part doesn't seem to understand and they'll just it confabulation an explanation. Well, you know, they might say well because you know, I I was thinking about this other thing because you said this thing earlier or something well that makes sense. I mean, it's almost like a supernatural experience. Right. And and you know, logically, you can try and find some sort of answer to it. But the answer you give and apparently the I mean, there's no indication these people were just consciously lying about their motivations the answer. You give. And apparently, the answer you seem to believe is is not true is just like you. You can come up with explanations for your own behavior that are completely wrong, and we can show why they're wrong, but you are not aware that they're on. It can be wrong about your own mind. Right. And even without a split brain. Of course, humans are very capable of of coming up with false reasons for whatever they believe they did. Oh, absolutely. Yeah. I think that's entirely correct. And that sort of what I what I'm thinking. We might be able to extrapolate here. So one of the most amazing things to me about this kind of research is is that this can happen to the brain for the most part. Nobody seems to notice it takes a lab experiment. Like this to draw it out like not the people who interact with the split brain patient. Remember that family? Members usually report, no major changes in personality or cognitive ability as David woman points out in his nature article the patients themselves say they quote, never reported feeling anything less than hole in the words of Michael Zonta. The severed hemispheres do not seem to notice that they have been severed, and they don't report missing each other. Oh, so this raises so many questions. First of all, why are they connected in the first place if they can be severed like this and not seem to notice that that's an interesting. They like, what's the reason for this? This connection second. How is this possible? Like, how's it possible to cut a brain in half? And have it not seem to notice anything different and not behave much different India? I mean, even the light of everything we've talked about it. Seems it seems kind of impossible. It seems seems like it's the like like it's magic trick a grotesque magic trick. But imagine on the list will maybe we should discuss a possible explanation for this after a break. Investigators have been desperate to figure out how that family flew off that cliff in California, and whether it was on purpose early the morning of March twenty six rescue workers repelled down the cliff where they lifted the dead bodies of three children arm to the point where I no longer. I'm calling this an accident. I'm calling it a crime who are these women, and how did they come to adopt six children two sets of three black siblings..

Joe Gonzaga California Michael Zonta India David
"zonta" Discussed on Stuff To Blow Your Mind

Stuff To Blow Your Mind

03:16 min | 2 years ago

"zonta" Discussed on Stuff To Blow Your Mind

"And it's not known exactly how many patients ever received a corpus callosum Demy in history of seen estimates including somewhere between fifty and one hundred total patients, I've read Michael Zonta estimated that there were over one hundred patients who had received one now, obviously, not all of these patients volunteered for split brain neurology research, but some did in one of the really interesting things to point out is that we'll have to keep coming back to this is that despite the radical nature of the surgical intervention cutting to him as fears apart and basically preventing them from communicating with one another most patients reported that their lives were. Generally normal after the surgeries their families did not usually report any major changes in behavior personality or cognitive ability. Michael Gonzaga, says that generally, quote, you wouldn't know it if you were talking to such a patient. Yeah. I've read that the really the only notable results of this outside of you know, perhaps some experimental stuff is gonna come up was that they didn't have the seizures anymore. Yeah. That that was the goal. And that was the the the primary experiential difference by and large people underwent this procedure, it the two halves of their brain apart, and they seem to mostly unchanged now on the other hand, I have read some anecdotes about changes certain patients faced especially right after the surgery during like an adaptation period, for example, a twenty twelve article in nature news by David Wolman recounts. The experiences of patient named Vicky who received a California me in nineteen seventy nine to treat terrible seizure. She was having a story that her. Procedures were so bad that one time she'd like fell on a stove and burned her back while she was having one. And so she says that for the first few months after her surgery. She would stand in the grocery store trying to pick items off of the shelf, but having severe difficulty just picking up items. She says, quote, I'd reach with my right right hand for the thing. I wanted but the left would come in and they'd kind of fight almost like repelling, magnets. And she would apparently have similar troubles. When trying to get dressed in the morning woman writes, quote, Vicky couldn't reconcile what she wanted to put on with what her hands were doing. Sometimes she ended up wearing three outfits at once. And then Vicki says, quote, I'd have to dump all the clothes on the bed. Catch my breath and start again, and I've read other accounts along these lines that a few split brain patients described things like this one image one hand buttoning up a shirt and the other hand following immediately behind it and unbuttoned. All the buttons. Oh, interesting. But these these type of descriptions are apparently not typical most reports indicate that people's behavior. Cognitive ability personality, all that was is mostly unchanged and even in Vicki's case after about a year, she was mostly back to normal in terms of everyday activities. She says she could you know, slice vegetables to cook and operate machines. And all that. And this is in line with other reports amazingly you can completely sever the connection between the two hemispheres of the brain. And most of the people you do this to function normally in day to day life afterwards before we even get to the other strange stuff..

Vicky Vicki Michael Zonta Michael Gonzaga David Wolman seizures California one hand
a16z Podcast: All About Synthetic Biology

a16z

10:07 min | 2 years ago

a16z Podcast: All About Synthetic Biology

"This episode general partner on the bio fund VJ punday, and I talk all about the field of synthetic biology with Jim Collins, professor of bioengineering at MIT and one of the pioneers of the discipline of synthetic biology. We talk about what engineering and designing biology really looks like when instead of engineering electrons, your engineering toggle switches for genes, including the scientific story behind the creation of that very first Jean toggle on and off switch. We also talk about the disciplinary differences and synergies between how biologists and engineers see the world what the engineering and design principles techniques or approaches that work best when applied to science how that looks different. When building a company in the space and thinking about for example, platforms versus products, and even how it's changing education in the field all the way down to middle school. So let's start at the very beginning. How did the field I begin to emerge? What's the sort of founding story behind Syn bio, you know, the very beginning. Really? Was the island of misfit toys, if you go back to the hundred ninety s the dominant story was genome effort, and what's interesting is the biomedical engineers did not play a major role in the genome effort in biomedical engineering departments the curriculum the research interests, more or less stopped at the tissue level and was only beginning to get interested in the cellular level in the late nineties. However as the genome effort was really picking up speed and beginning to produce these parts lists for different organisms. The leaders of the genome every began turning to the engineers and increasingly to physicist to figure out help them figure out how these parts put together. Can you explain what the missing information specifically? So the sequencing would lead you to the ability to annotate genome to identify coding regions identified the genes identify promoters. But couldn't really give you information about dental on networks that were making up these living cells, and what way with jeans. Proteins yarn a elements interconnected and leading to the interesting biology disease, biology, the notion even of network was not dominant or even prominent within Malacca biology. You said one thing that really struck me reduce said, it was not necessarily biologists. Computer, science physics you. Then had this effort to really try to pull the physician the engineers into molecular biology, and why them I think because we deal with complexity well to get after what became systems biology was the recognition that you needed to embrace complexity before the network, what was the predominant kind of idea you had really the fixation on the actions of single protein single jeans, and at the level of kind of integrating those you had pathways and you began to see efforts primarily out of Stanford beginning to use mathematical modeling that opened up the doors for folks like me to do basically systems biology, could you reverse engineer these networks, and let's actually explain what you mean by that reverse engineering large-scale now because that's. Not a concept that's native to Zonta box. It's an engineering. So it's a strong, electrical engineering kinds of the notion is that you have a system that's interconnected or wire together. And so the ample the could relate to many listeners would be the wiring system or the wiring setup of your house say you buy a new house, and you've got a circuit breaker box down in the basement. And let's say it's not labeled by the previous owners, just like my house, my so what do you do you go down? And you flip the different switches on or off. And you discover what they connect you. She a beginning to reverse engineer. The circuitry of your house, you then through additional experiments that you running the microwave same time with that. In fact, oh, those two circuits are actually interconnect even further that's not represented by that. And you begin to infer the underlying structure of the wiring diagram of your house. But our first response was to run away from that promise fast as we could because there were insufficient data to do in the late nineties. We just had microwaves appear technology that is no longer in vogue. But. Would allow you to survey thousands of genes and their expression states simultaneously with another given. So these are incredibly expensive, and when I got pulled in their only seven publicly available data sets. So the idea you could reverse engineer large-scale network is ludicrous, and what were those types of data that we're lacking. So there was largely expression data's in those days. It was really micro Ray. So we even though the technology used appear we didn't have those data sets. We didn't have a wetland. We didn't have the capability. And so we began to think about could you put together molecular parts in a network instead take a tinker as approach to molecular biology. So the depressions the output was the like how were you perturbing it them? Well, so on on. That's how we had no perturbation, right? Perturbation would be the going to kick the system where you're going to stimulate the system. Switch flip the light switch. Let's say you have your radio on and your kitchen upstairs volume on you're gonna run down says you're gonna flip the switch one by one until you hit the volume go off that's a pretty Bache to your circuit that allows you to map out the circuit. We introduced tech. Seeks to do that. But even before we get there we stumbled into what became synthetic biology. We said, okay. Could we instead of figuring out how these large-scale networks wired together, we put them together ourselves could we do it with intent? So could we design circuits with desired architecture and a desired function, and that's the key difference right in this entire approach that you're designing exactly we are. We are really doing biology by design in some cases, we're taking natural parts and putting them in noon, different ways. And other cases, we're building new parts, and then putting those together in new or even established architectures we spent about nine months thinking about what we wanted to build and we arrived at building genetic toggle switch and this was motivated by electrical engineering, where toggle switches, which are also called flip flops are as latches a very simple memory elements memory, which is can be flipped between zero one in the binary state or on off by a transient electrical signal. Toggle switches are at the heart of digital member. And we cycle through many different schematics and circuit diagrams and arrived at one that was basically mutually inhibitory network where we have two genes that are set up. So the always want to be on. But they're arranged to the trying to shut each other off. And we showed mathematically and computational that you should be able to have it as a by stable system, it either ones exists in state aging one is on gene two's off or state Beijing to his own gene one off and he principal. You should be will flip it between those states by translate delivering a chemical or environment. They would shut off your currently active, gene allowing the gene had been kept off by that active. Gene allowed to come on. Now would produce enough protein that would shut off the Gina had been on in. You can you stems and you flip from state to state of state means like electrical engineering except not electrons. It's now a wet circuit. But in this case, we actually did mathematical modeling computation, and now the next segue was I reached out to Eric is instead who was a program officer at the offset neighbor search who is run. Being a gene circuit modeling program. And I tell them what we're doing. I more or less called him once a month for every over six months, it could you give us money to try to build this in a lab, and he kept putting off putting off and I basically warm down. I said, you know, I think this could be really big, but we need to be able to build this and I'd like to see party program. And was the reason why wasn't clearly I mean clearly having an on off switch like that seems incredibly powerful. Why was it not immediately? Just because it seems so hard to do we had talked to about six or seven very serious molecular biologist who told us this couldn't happen. This couldn't work. They said for it to work. You're going to have to have a very tight off state to very tight off states. That's going to be impossible. You're gonna have to introduce a very large plasma the it's going to put a burden on the cell, the cells not going to like this foreign element the joke was they usually Patterson I hesitate boy stick to engineering because biology is really complicated. I mean, those do sound like reasonable concern. I had heard incredibly talented graduate student Tim Gardner who was a mechanical engineering train student at Princeton. Tim, presented our modeling. This is a famous in our meeting where he was more or less shouted off the stage by some very serious Mike about is including future Nobel prize winner who said it was impossible. This could not work part. Tim who was green and Michael biology had been a mechanical engineer who had designed autonomous helicopters to fly around. Princeton didn't know anything about you presented this engineering concert. Nonetheless in nine months, he had a functioning by stable toggle switch that the same time. We were doing this, Michael Ila woods and STAN Liebler who were to physicists sitting in. Both the physics department at Princeton and the micro biology department at Princeton, we're taking a remarkably similar approach to synthetic genes. Circuits completely independent of us. An ambulance toss in that we worked in e-coli with three different repress or proteins using dynamical modeling they worked in E coli with the same three repressive? Proteins using dynamic modeling and instead of screening a toggle switch that consisted of two genes. Trying to shut each other off they created what they call. Presa later a ring oscillators simile motivated by electronics, electrical engineering. They consisted of three genes in series. Eight tries to shoot a BB to showed up C C tries to show. Hey, those same parts just different same different circuit. They submitted to nature. We submit our nature. They end up being published at the launch the turn of the century in January late January in nature back to back the next week, the headed aditorial said, oh, you know, physicists beginning to move into Mike about it and says you should look back at those two papers because there's something interesting going the raising point about how everyone on the biology side thought this was impossible almost like the biologist some of them have an immune response against engineering. That's a great way to put a that seems to continue even today. It is when I have many, many, close, friends and colleagues who biologists. But I think within different academic disciplines as often too much tribalism. So the very common critique that we get to they're not biologist or they're not chemists or they don't know basic biology. Don't know basic emission, I yes. Yes. Yes. Yes. Yes. I don't think it's fair though. And I think that these problems really combine if municipal reproach and different perspectives. So we don't know the detail at the level that the biologists do

Engineer Princeton Mike Gene Tim Gardner Jean Jim Collins Middle School MIT Zonta Box Michael Biology General Partner Professor Beijing Nobel Prize Bache Physicist
"zonta" Discussed on KQED Radio

KQED Radio

02:22 min | 2 years ago

"zonta" Discussed on KQED Radio

"The soundtrack of the film adaptation of Stephen Sondheim's musical into the woods. So I don't I don't know when the last time you heard that was Emily blunt. But how does it sound to you? This sounds all right. It sounds to me. I I love. Did you get? I mean, I I love I love that song. I think it's such a beautiful song, and such a sort of bonding moment for the two of them who is Ted tend to bicker and be at odds with one another. And I found the whole sequence singing that with him very funny and very romantic and I absolutely adore working with James. He's just the best crazy funny. Just so exciting to work with. Did you did you meet Stephen Sondheim and preparation? What? What did he tell you? Did he give you any advice or insights that were really helpful? I singer or portraying the character. He he was in the recording studio, which we were all terribly intimidated by my husband, John was there when I was recording. It takes two with James. And he said that Stephen sometime loved it and was sort of having his arms in the air was just sort of like floating along listening to it and the song finished. And apparently, he just went off that was fabulous. And so that made me feel good. And then I recorded another song and he came in. And he was like he was like, I think you're just thinking about it too much. I think you need to like be right right on the beat you need to be right right on it your like dragging it. And I was like I'm sorry. David zonta. It went from thinking I could do no wrong to really disappointing him. He was just letting it drag just stop over thinking it, you know, I guess he's honest. Let's take it is a song. He should be the which song was a. Moments in the words, and so how did you change after that? I just listened to stop dragging it probably stayed right on the beat. Did it deflate your confidence? No, no. I like the notes and the criticism. I think it's good. It kind of does you up abate? You got to find a different approach. Well, let's take a short break here. And then we'll talk some more. If you're just joining us. My guest is Emily blunt. And she now stars in Mary Poppins returns as Mary Poppins. We'll be right back. This is fresh.

Stephen Emily blunt Stephen Sondheim James David zonta Mary Poppins Ted John
"zonta" Discussed on Speak For Yourself with Cowherd & Whitlock

Speak For Yourself with Cowherd & Whitlock

02:55 min | 2 years ago

"zonta" Discussed on Speak For Yourself with Cowherd & Whitlock

"Captain's orders Shawne Merriman and TJ Lutheran Zonta are but. Ourselves. What got oh. You know? I got love for the big uglies down there in the trenches. Not just Jason Whitlock. Not just me. But that dues dues start off. With number three. We go into the basics. Pop Warner level a little man, whoever your hit me up. So I give you some pub. But boy you out there beast and looking at big dog bigger than everybody else. First of all shut up to your DNA. But then look at him. He's gonna get mad inside hands. All those who sit that little eight year old down in this chair. Yes, you should relax. Oh, God got him pushed in the worst position possible. And issue will pop Warner guy us, just go fish them. All great technique. Look at his still get in on the tackle Louis SIS right there respect to number three debt dues. Do make sure you hit me up. Number two, this go to Kentucky collegiate level on Beker. Josh allen. I dip you dip. We do look at this right here that nip oh Merriman now buffalo Merriman. This is San Diego. Lights out target area. Name we always practice to get to that target area. Try to make sure that we don't get pushed off of that. How do you get there? What which arms which legs and hips? Most important look at this are right here. He's going to bring that arm up at the rip. All you see right now, seventy one arm just collapsed. Oh, you know, why seventy seven collapsed because of that rip right there. Now, you have to finish every move by locking them out if not he can't recover and push your quarterback. Oh, Josh Alison, none of that number two that do do. Now. Let's go to number one Jaguars defensive in Yanic in way. Who was this Sean mature show them some love cat, scratch fever? Oh, no around edge spent move o- sachse view, take this L right here. Now my show you how you get sadda-. Great position. Right. Thereby Matt feeler, but he has his arm out there. You gotta punch with that arm. Instead. Now, you can see them on man Jahic. It's like, oh, I'm gonna commit because somebody done left. Oh, the inside opus. Now the door is open to the inside. I'm going to commit by locking them out. Oh, and that arm. Remember, I told you you'd better punch them with. If is this out there is the target. He's gonna collapse on it. And once again, locks them out been roughest burger, take this L Jahic. Celebrate brother your number one that dude of the week. I was good stuff. Got a guy at time. Now for some big stories. Let's move to Green Bay surf where Aaron Rodgers today plans to donate one million dollars to the victims of the California, wildfires Rogers who is from northern California posted this video asking for support and donations. Tell you listen as many of, you know, the California wildfires have devastated countless communities in northern California where I was born and raised the city of paradise burned to the ground and many of the residents that got out are now displaced in my hometown of Chico and across the north state. I personally to my friends and the mayor of.

Merriman Jaguars Jason Whitlock Shawne Merriman California TJ Lutheran Zonta Louis SIS Warner Josh allen buffalo Merriman Josh Alison San Diego Matt feeler Aaron Rodgers Beker Chico L Jahic Green Bay Kentucky Yanic
"zonta" Discussed on ESPN Chicago 1000 - WMVP

ESPN Chicago 1000 - WMVP

02:46 min | 2 years ago

"zonta" Discussed on ESPN Chicago 1000 - WMVP

"Selling price. Manticore sixteen. Eighteen. You're listening to the National League championship series on ESPN radio and the ESPN app. Go to the bottom of the third here at Dodger Stadium with Chris singleton ibn shoulder. The dodgers lead the brewers wanted nothing and gave for the NFC. Yes. Demanding Machado is no deleted off against Freddie, Peralta, grew with shift off reappeared is on the left side of the diamond the outfielders deep and straight away from shadow who popped up a foul territory. His first time dodgers. Yes. Up wanted nothing. But also left five men on through the first two innings. Brian dosier Zonta. Thank you k-. Hernandez. Peralta ready to go. I Mitch up high. Wondering maybe if there was a chance that even though Gaucher's got the RBI single tonight. Now, the Peralta said forget solace. Have maybe babe Roberts would go to somebody. Like, Cody Bellinger, took Mitch it for dosier. He Hernandez comes into play second base. But have you warding dosier for that RBI single one outside goal to? And let's be honest balance is really struggling. But he also could have done it with Jack Peterson who tailored centers got a lot of. Yeah. I yeah. I think you just try to ride it out with dosier to out big knock, but get the dodgers all the board score. I tonight. Not the guy maybe he's due for a big night tonight. Two. Oh, two Machado at ease for a strike to would wanna Chato thought. It was low might have had a case of the call goes the brewers way. So it's two balls and strikes. Dan. I think about that. You know that healthy balanced between the analytics that we have. But also just the human field came at this guy. Right or left might be locked in right now. Let's see we get the two one. Fastball to swing a ground ball up the middle but station, right? There is scope the second basement and he'll throw out Machado one down. Resist bright is still has to be a little bit of room for punch or feel or something like that. Right. Yeah. I mean, that's you know, the players I think you've done a nice job. Would you look at? Let's just look at both of these teams right down the series in both teams in their players had had to make the adjustment to put two splits and switching the bullpen roles and everything else. So there's there's been good it. But with that said, you also ought to have a manager and coach staff it has a feel. Also, I bitch to.

dodgers Machado Brian dosier Zonta Peralta Hernandez Dodger Stadium brewers ESPN Chris singleton Mitch National League Jack Peterson Cody Bellinger Gaucher Roberts Freddie Dan
"zonta" Discussed on KNBR The Sports Leader

KNBR The Sports Leader

01:43 min | 2 years ago

"zonta" Discussed on KNBR The Sports Leader

"That's. That is absolutely losing your cool. This is a guy who seems like an and I think that's true. I think he had a competitive fire and just it all came out at one time. And he made a good comment there about look if people would just tell each other how they feel I feel like the reason the warrior, and I think we all know this glue guy for the warriors Draymond green. I think he's that guy. I think everybody knows look Draymond is not going to mince words with me. Draymond Zonta cut it sideways. Give me a different explanation to keep it software. Make me feel good. We've all seen the video he and Katie getting into it. And I don't think anybody is scared that that's the reason. Kevin Durant may leave after the year. Everybody knows Draymond green is the one who keeps guys level on the floor even when he's on the floor, and he's the one rubbing guys the wrong way because he's the loud boisterous passionate one. I just think that's that's where we are. And I think this all plays in to the NBA being one of the most entertaining things in all of professional sports, not just on the floor but off the floor as well. Are you want to check in on Jimmy Butler homeless Garoppolo dude? I know I'm having withdrawals. John middlekauff in the athletic wrote a piece yesterday already calling for Robert solid. Check this headline five defensive coordinator options if the forty Niners decided to make Robert solid their fall guy. Couples options are good couple of saying you know, what I don't want a first time D coordinator yet again. Just gimme somebody new also five weeks, and I'm not sure we're ready to make that decision. Quite yet. Italy Cambier you want to check in on that. And we'll hit on that. As we get ready for Thursday night. Football ahead of NFL week six all that more coming up in the leadoff spot on the sports leader. NBR's San Francisco. A Cumulus station. Enrolls for marketing.

Draymond green Draymond Zonta Robert solid Kevin Durant Draymond defensive coordinator Jimmy Butler NBR coordinator San Francisco NBA NFL Football John middlekauff Italy Katie five weeks
"zonta" Discussed on The Rewatchables

The Rewatchables

03:17 min | 2 years ago

"zonta" Discussed on The Rewatchables

"And so he feels like he has access to this experience and he always writes about it, and he always has Sam. Jackson is movies in every time. This comes up Sam Jackson's like Gwen Zonta, racist coins. Cool. I love coins dialogue, and he really understands something and this we go through this every single time. So the civilian speech he said is based on a conversation that he had with a guy that he was friends with was black who told that story. He puts it in the words of a white guy. So it's more offensive. This is speech also is rooted in a very like, that's very true to life, kind of character of a guy who's like very lonely in reads a lot lotta history books in his, like I know a lot about the world because I read a hundred percent. It's a fucking guy that I've definitely met over the course of my who's just like guess what you ever read this book. He didn't read this book. I'm gonna tell you something about this. Yes, and you're like, oh, great. Here I am going for arrive at this guy in, and that's the thing I think is very important distinction about this is that there is like probably for better for worse. We're losing our ability to distinguish between the creator in the creation and whether or not the characters that we see on screen should match our moral values, right? And whether or not seeing somebody with moral values that you find reprehensible at times, it still makes them worthwhile characters, Toowoomba other, it's art and it's fake. I, I've never had that problem. I'm also a white man, so I've never been like really like the target of of the things that would make me upset about it. But we've Tarantino a comes from tradition of pulp, crime, gritty, fucked up people who are not good. Nobody in this movie is good, and like even Clarence and Alabama for as much as we like them are essentially criminals. And it's just like, you just have to kinda like change your compass a little bit when you're watching this stuff. And I guess I'm just. Personally, like way interested in these kinds of people. But I never get confused about whether or not like Tarantino is racist or rethinks like this is really cool. It's happening to Patricia Arquette, but let's talk about the other stuff in the movie. We talked about this last rounders too. It's like this a movie about dirtbags in crooks movie about dirtbags on crooks. They act a certain way. I put the plant speech down for this, but at the same time I don't think it's age bad. They I just think the country's changed and in whatever new prisoner and people like, oh, what does this? But the whole point of that is those are the characters. He's not condoning the dialogue and the guys hoppers basically, nose is gonna die. Any tries to get in Washington and he's like the worst possible thing. He can think we should still be able to do that movies the Gandolfini Arquette seen. I'm going to defend the scene and I think it could still happen in two thousand eighteen. The whole point of this movie is everybody's bad. The behavior has to be over the top to warrant like, you know that were invested in these. Characters, and she's the hair of the movie and she wins the scene. She kills you and it goes so over the top in a way that is, you can't believe it. She's this Hooker who has had this calmer, and and I'm rooting for him, invested in her one. I want them the cell, the suitcase, and now that Gandolfini is in the hotel room and and she's for some reason that scared doesn't turn around and run tries to deal with them. It goes super-duper dark. He's just pounding her and she survives and gets out of it. Like to me, it's no different than Houma Thurman and kill Bill or something..

Sam Jackson Patricia Arquette Gandolfini Gwen Zonta Tarantino Washington Clarence Houma Thurman Alabama Bill hundred percent
"zonta" Discussed on 760 KFMB Radio

760 KFMB Radio

01:46 min | 2 years ago

"zonta" Discussed on 760 KFMB Radio

"You hear this Jeff Sessions might still be, attorney general coming up. Today on the Brentwood will show at three we'll break down all the big stories AM seven sixty talking breaking this Zonta someone who. Would bring their kids to drag Queen story I would love to have that conversation maybe more than anyone you know the question. If you could talk to anyone dinner. Live who to be oh Abraham You're going with drag storytime I, wanted to talk to a dad who would. Bring their kids to drag Queen. Story done by that's interesting. Because I would have. Liked to talk to someone. Who would set up a go fund me for Duncan Hunter and yesterday we got to talk that person I bet. There's gotta be listen we always play this game there's gotta be someone there's someone's gotta be. Selling there's some of the now there's a dad listening now. Who would or has. Brought their kids to drag Queen story our that to me, is, odd A. Lot of things you could do You know what I've never done I've never, been to pow way park the train Oh. Pulled, Palley. Palley. Palley part there guy do that yeah sounds great Jack would love oh sure. Beautiful, can't wait, to get tickets to go to? The earned Space Museum the funding well. You know who's the king of. The arts because we've got to go to that that's. The thing we gotta live animal park? Made things so much fun tons of fundings do Drag queens story hour, I don't that. Seems Really low. On the. List but Eric we please, play. Clip twenty one forty five, sir Governor Cuomo came. Over where these are all millennials and New York City governor Cuomo came out.

sir Governor Cuomo Palley Jeff Sessions Queen Zonta Duncan Hunter Brentwood attorney Space Museum Eric Jack New York
"zonta" Discussed on KNBR The Sports Leader

KNBR The Sports Leader

01:56 min | 3 years ago

"zonta" Discussed on KNBR The Sports Leader

"Valley get through this jam two one he pitches zonta all slashes edit it hits it past the third baseman feel on goya's into score here comes crawford around third he will score standing bruce bochy makes the move and it pays off bob los out of all knox into as a pinch hitter and giants have tied this game at three we now continue with murph and mac on knb are six eighty yeah why not the twenty two and twenty one and three and a half out and going for the sweep today although already boats he's talking about sitting sizzling hot brandon crawford who had four last night my be out there and play in your boy gogo at second bit well go go needs time to second bay i could be looking at a middle my buddies fiftieth birthday could be looking at a middle infield of tommy and gogo speaking of the middle and he'll go go give me joe panic update real quick when is he sort of more weeks till even starts snack those starts this weekend mcwilliams stadium some mac and and and then so bum and mac would like to say or are getting closer gary likes nicknames i know and bummy and mackey will be coming back sooner than panicky joey so anyway we got that we got the warriors tonight at six o'clock so so today's a great day because you go day baseball all on your own enjoy it crack a few peanuts cough a beer aero warriors game you don't have to even switch over on a commercial to check out a giants reds because that's a good call that went a larvae in the book like that right off your play tonight stuck around.

zonta goya murph brandon crawford tommy joey baseball giants bruce bochy mcwilliams stadium mac gary mackey
"zonta" Discussed on KLBJ 590AM

KLBJ 590AM

02:18 min | 3 years ago

"zonta" Discussed on KLBJ 590AM

"A hard time affording reasonable housing in silicon valley the top destinations are sacramento austin and portland the texas state university students says that she flushed her emotional support hamster down an airport toilet when spirit airlines told her the hamster could not fly belen allah go see us as it was a devastating choice to flush little pebbles down the toilet governor signed it be two circular mean little like the tips on oh you should use lever or fleischer domitory later this or that i know him some people in hungary budel and i agree it is brutal but arm in the fundamental that i will then uh had no way of getting own in other than in the plight she knell has it attorney spirit airlines says it's a boy was wall to ban the hipster bud they deny the employee suggested that the toilet flushing occur at the airport it's eight thirty three now let's get you up to date allston zonta traffic with malig debris it that third iraq on thirty five southbound at howard lane has been moved over to the right shoulder we're still looking at slow traffic conditions though from fourteen thirty one we also have reports of a collision on thirty five at northbound at slaughter enough that's about where traffic starts to slow down extending into the downtown area and a wreck reported at raza's intense street your next report's at eight fortyfive i melinda brent with austin's on time traffic this says it a cloudy day today with a high of sixty five than we'll have low clouds and fog along with a couple of showers developing tonight it woolsey very mild low of only fifty seven by fog tomorrow morning then it'll be cloudy with shower too in the area the high seventy four a touch of rain sunday morning otherwise cloudy breezy and becoming much colder with temperatures in the middle 40s from the weather center i'm meteorologist people do not think trump is not unhinged insane losing it or anything of the sort we narrative millions of people believe just the opposite in fact would encounter bunch of truth at it's the other people that are coming unglued rush limbaugh and what they really can't believe as they have not able adorning south they fired every weapon they've got nothing is getting rid of trump rush limbaugh weekdays.

iraq howard lane raza austin trump limbaugh sacramento portland texas state university fleischer hungary attorney melinda brent woolsey
"zonta" Discussed on KCMO Talk Radio

KCMO Talk Radio

01:31 min | 3 years ago

"zonta" Discussed on KCMO Talk Radio

"It line were you also find harry's hammered with great food wine n 64 craft beer zonta wind experiments y k cmo mayhem 710 transitional one point one fm jc effects hd 2 harrison ville promo heartland of america is used kcm all bitter cold icy roads i'm christopher cruise record low temperatures forecast from the mid west to the east coast today noah meteorologist patrick burke says the cold will even affect the south we don't have any major storms that the socie with the cold air on but there are some minor storms serb minor ripples going on in the atmosphere which will produce a little bit of precipitation and temperatures are holding up as you go inland that some of that may fall as the light freezing rain or out sleep nebraska could record the lowest temperatures in one hundred thirty years today and much of the country from texas and oklahoma and eastward to arkansas northern louisiana mississippi and alabama will have icy roadways but million or so people expected to pack times where for the drop a big ball tonight we'll be dealing with temperatures as low with ten degrees the coldest in decades president of the times where alliance tim tompkins says the cold won't stop the fun when that confettis falling in there's people's wishes from around the world britain on that confetti and the music plays new york new york if it can make it here you can make an anywhere and then you know what what a wonderful world as an unislamic lay it.

harry america patrick burke nebraska texas arkansas mississippi president tim tompkins britain new york oklahoma louisiana alabama one hundred thirty years ten degrees