19 Burst results for "Vaulter Longo"

Valter Longo, PhD - Nutrition, Fasting Mimicking Diets, Regeneration and Longevity

Medicine, We're Still Practicing

02:49 min | 1 year ago

Valter Longo, PhD - Nutrition, Fasting Mimicking Diets, Regeneration and Longevity

"What's the difference between fasting fasting and fast mimicking the first thing most people would view as just water? Okay the water. Only fasting could be US effective. Do but at the same time. It puts the patient at risk for all kinds of problems hypoglycemia hypertension Law Salts in the in the system etc etc.. And so the festival diet. Give us an opportunity to basically standardized diet to make sure. The patient does not have these problems now. How many calories is they're being consumed during a fasting mimicking diet? Well festive Megan Diet. Is there are many versions. Because you know we have a version for out immunities Version for Alzheimer Birth for cancer vary in the clinical trials but Simpler four days is very low. Calorie starts about six seven hundred calories and goes down to three hundred. We want to get him four days And the reason for it is to really be adjustable to all the conditions that they chemotherapy. No the therapies are carried out and The the one for regular people is. He's eleven hundred calories and they won going to seven hundred and fifty three hundred calories and two three four five The one for our immunity seven days long and and it's similar to the one for regular people are very different content Alzheimer is about fourteen hundred calories. They won And then it goes down to Nine hundred nine hundred and fifty calories and so we're adjusting based on the age conditioned frailty and many the different needs for healthy people. Are you putting yourself through a fasting mimicking diet in some sort of cycle. Yeah I do it twice a year twice a year In in the reason for that is I normally have a very good diet. Especially -Tarian Remember fish couple times a week and then just Vegan. The rest of the time So Oh I think it's That's about all I need to do that. You're Italian do you still drink wine. Drink wine. Yes how does that happen coffee. The and there's no animal in in wine true true but it's it's definitely not Low sugar no wine wine I mean people if you look at the Meta analysis and I'll goal consumption up to five servings a week is actually either neutral or a little bit. Ah slightly positive and lifespan. So unless you have all the risk factors for for Diseases for which. Alcohol is also respect than than you than alcohol is fine in within this this consumption limits.

United States Alzheimer Birth Alzheimer Diseases
Valter Longo, PhD - Nutrition, Fasting Mimicking Diets, Regeneration and Longevity

Medicine, We're Still Practicing

07:38 min | 1 year ago

Valter Longo, PhD - Nutrition, Fasting Mimicking Diets, Regeneration and Longevity

"Dr Vaulter Longo originally planned to be a rock musician. But luckily for us he became an international rockstar doctor. In the field of longevity evident nutrition Volker is a professor and director of Gerontology Biological Sciences at the longevity institute at the University of Southern California and he's also the director of longevity and cancer programs at the Institute of Molecular Oncology in Milan. Italy a little over a year ago Time magazine. Gene named DR Congo one of the fifty most influential people in healthcare for his work on forty two international clinical studies and groundbreaking research on the fasting mimicking diets. Away to read your body of well. A mutated cells while rejuvenating are healthy ones. He's the creator creator of the five day fasting mimicking Diet and the author of the international bestselling book the longevity. I I was nineteen. I think when I started working on aging and At the time it was a music student in Texas University of North Texas. FAMOUS JESSICA CESCO. Obviously it was in my head all along because I did not think about what I had to do. I say I have to study aging and I always thought what an incredible challenge bald scientifically but also taught. Why is every doctor working? and He seems to me and like that's where the problem is So yeah so I. I have to say beside the years very early years. I I've always worked on this that's that's all I've ever then. Because I had read about you that you had initially wanted to be a rockstar. I started the same way my my initial thought was to be a Rockstar Rockstar. And then I realized that I was lacking one key ingredient and that was talent So I quickly switched to something that I felt I could do better and you still involved in music. It's a little bit more now I think in the You know fundraising levels over thinking of doing some some cancer onset or something like that to raise money for research. Yeah so I always Worth an aging. Since the early nineties was like enough to be a student of Roy while for Ucla was a pathologist there and it was my first mentor new at the time. The the world Most well known person working on calorie restriction and the longevity and saw I followed up on his on his he's working and So for the best Twenty seven years. We've been focusing on other. Take this old idea of station fiction and make it make it a newer idea that can be brought to the clinics all over the world so so Dr Longo. You've been looking into various diseases that are related to aging That I guess are anti longevity Diseases such as cancer and and auto immunity and cardiovascular disease obesity and how these diseases might be affected and possibly even untreated with a modification of Diet and With intermittent fasting. Yes so what we really focusing. Because he now is What I call the longevity program and and and saw a mouse Has It on. DVD program that is it's about two and a half years long Into I ran. The lifespan is two two and a half years but this the health span is maybe one and a half years of mice started developing cancer maybe after one and a half years out of the two and a half years lifespan so then the idea. Da is why is it that people don't get cancer in most cases until they're forty or fifty or older So there is clearly Did the possibility of getting cancer is under the control of this program. So what we're really talking about here are cells that have kind of an aging problem. Yeah that's what we're going after we're going to have to the fundamental changes in cells And in the collection of south that eventually will lead to dysfunction. What does the Diet that you are proposing that has been shown to have these immune modulating effects and the longevity? Well let me just interrupt for a second here You know I think we're talking about two different kinds of diets there's one there's the Intermittent Diet that you would do three times a year optimally on. But then there's your daily diet so can you comment on each of those we did Epidemiological study using the CDC database. A few years ago. Oh where we showed that Americans eight the highest level since they had About seventy five percents increase risk of overall mortality about three to four fold increased risk for developing cancer Compared to those that had the lowest protein intake so this is about you know out you eat every day and Now this was true only up to sixty five so if you When when the CDC asked the question two eight year-olds There was no longer true. In fact people eight year old were reporting. Having a law protein intake did not do very well So Oh you know this is really important that To understand that this is not we liked to have simple answers like low protein high-protein. This is good this this is bad. It doesn't work like that. It's a complex environment. You just have to learn how to navigate it and and it's not you know once you learn and you have the right physician or or or or Dietitian helping you. I think is fairly straightforward but there are a lot of data that says that high fat diet has an increased risk of colon cancer and breast cancer Animal fats and high protein seems to be Bought associated with increased mortality increased risk for Cancer increased risk for cardiovascular disease the ideal everyday diet seems to be a fish plus plus Vegan Diet That is you. We know high nourishment and low protein Then the fast moving the festival making that is really something very different. And it's not even intermittent in nature. Can you describe the intricacies of the fasting mimicking diet. What does it entail? Yeah so the fast making diet is is a law sugar. A high fat good fats are low. Protein colorist diet and fats. By that you mean Omega three versus Omega Six. Then what are you referring to good fats. I refer to Type of fats. That are associated. Will Jerry the And health span extension so the the olive oil plant plant based of a certain kind that the is for example Avocado as an daas thus far not been associated with longevity extension but Not have and so as olive oil So those yeah that's what we're focusing on the ones that provide the fats the certain type of fats but also that are being consistently associated with higher health status in longevity

Cancer Dr Vaulter Longo CDC Time Magazine Professor And Director Milan Italy University Of Southern Califor Omega Six Volker Jessica Cesco Gerontology Biological Science Institute Of Molecular Oncolog Gene Texas University Of North Texa Dr Congo Director ROY Jerry Ucla
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

02:04 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"It's a pleasure talking to you dr longo here your work is groundbreaking the work you're doing is inspirational i think we're going to be seeing and hearing from you quite a bit more your book the longevity diet is groundbreaking and i wish you only the best as you continue to do more research and it's an honor and a privilege to help you get your message out into the world so thank you for your time today if you're interested in vaulter and his work pick up his book the longevity diet if you're interested in learning more about the fasting mimicking diet you can go to prolong on fm d dot com and they have all the information there you have these kits that you can order i think it's important to say that vaulter himself does not profit individually off of this whatsoever of the money that he earns from this goes directly into funding research with what's the organization called via cures that are what is creek your steal okay cures foundation that i started with the idea i had like every day i have ten cancer patient or people without immunity and then whatever or these es and they're like desperate and i realized that doesn't matter where you are whether you report a rich there's really very little out there that helps you with a in a in a serious way and say okay you have cancer i mean there's a lot of quack korea there but it is not too many people offered in the college that tells you hear the drugs we're gonna give you then people were faced with internet good luck to you and so create cures really about war can somebody do today now twenty years from now about today that is gonna make their tara more effective is going to make the side effects lull where so he's going to help him and some cases we loved on the clinical studies some cases we haven't but the patient can awaits and so we sort of have to act now and that we felt as important we're doing it all over the world now with many many different hospitals and we're starting to see the doctors slowly.

vaulter korea dr longo twenty years
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

02:34 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"Charles one and a few others melinda but now with the brain people you should meet these guys connect you is there anybody who who for whom the fasting mimicking diet would not be appropriate yes so pregnant woman wade below it and bmi in point five or something like that people with diseases they're going to need dr people are taking drugs especially metabolic drugs in solan particularly very dangerous nation you can actually die if you combine insulin and fasting fasting mimicking diet yeah so i think in general if somebody's l d they can talk to the nutritionist and that is an expert in fmd's and they will take them through but if somebody has a disease they they need to run and by the doctor and then the nutritionist and the doctor can can work with them to to see if it's doable right and the preferred preferred protocols to do this five day program three times a year like once a quarter for a year well it depends right so if you somebody who's thirty two year old at the late that is on a biscuit tarian or vegan diet and everything is perfect let's say you probably want to do it twice a year and somebody who's obese got high cholesterol high blood pressure maybe once a month until the move to the lower category and then it goes maybe once every four months and then and then every so i'll say on average people are probably due at one once every four months and then depending on where they stand between the thirty two year old hatchet and the o'brien or respect yeah i got you all right well we got a we have to wind this down but i have two questions i can't let you go without asking the first is if somebody's listening to this or the washing this and they're health conscious they're interested in taking care of themselves but this is brand new information they never heard anything like this before what's the what's the thing that you want people to bear in mind that they might that might not be self evident to the average consumer about how they approach their their day their diet their lifestyle habits.

fmd Charles solan o'brien thirty two year four months five day
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

01:57 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"What is the impact on cognition of fmd yes in the mouse that are very clear impact the meaning that they are cognitively sharper they remember better they learn better particularly when they're old and the but also when they're young by ucd's particularly when they're all now we're doing we've done some special fmd's with my sue on and off on alzheimer's but now we're doing the human fm the were destined now in mice that multiple alzheimer models and the idea is came we protect the can we protect the brain against alzheimer even when we posed the human mutation that calls alzheimer's in one hundred percent of the mice we have some mouses called triple transgenic and that's all these human mutations they cause problems in this bid i'm lloyd accumulation tau for data tau saw yeah so then awfully within a year we'll have the date on that and we're starting to clinical trial which is funded by the ministry of health for a randomized clinical trial on alzheimer's patients how fast and making diet so that would be very interesting particularly because there's really nothing dementia right now and and so these would be something that could be rapidly moved into their into clinical use are you familiar with dean and aisha sherzai loma linda with their i forget i think it's called the brain health unit they created a department there and they're having some pretty tremendous success working with early onset alzheimer's patients i had them on the podcast they're doing really cool we're collaborating with.

ucd alzheimer dean one hundred percent
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

02:01 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"As soon as you start removing glucose in the moving growth factors and jeff one etc and adding antigrowth factors now the cancer cells are going to have a problem and that's what we see that's why we see the fasting fasting mimicking diet being effective is chemo but particularly we city is working together and that's where the sun comes in right the sun is the chemo and so you know you have no water and you have the sun hitting you you're going to be dead it's just a matter of time right it's amazing how that's worked out that it has the desired effect on the cancer cells which is to hopefully make them go away and at the same time strengthening the healthy cells in may have now worth out and might be volved right and so we're starting to suspect that think about sleep right so you sleep and sleep is now there by by mistake right is is is forcing you to rest for our many hours so we're starting to think is a possible that because all these organisms mostly stayed east bacteria mostly they stay starvation mode once in awhile this that eating right humans were not in that situation but fasting was probably so common they you didn't have to force anybody to do it because they were forced by the conditions right so then what if fasting was the moment where the precancerous cells were getting killed and and the now you use it to protect your cells in their moment of starvation from the sun from whatever other problems and toxins you might be exposed to so it may very well be adopted process where you're starving protect your your good salads and protect your jeans and then get rid of sales that are not functioning anymore also eat him yeah in the same way that that exercise is good for you.

"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

02:20 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"During a standard nutrition nourishment state right and why five days how did you come up with five days as the window well you need to break down right you need to glycogen and then you have about three days where you you benefit from from now consuming only and as we shouldn't in the clinical trial this'll fat right so the body now goes exclusive doesn't touch the subcutaneous fat it goes after the abdominal fat as it's only or major source of energy so now you suffer less for the last three days you break down the stem cells on are starting to get activity and you have enough of a window that you can start rebuilding should go much shorter is never any destruction there is never any cleaning up and therefore there's going to be minimal or rebuilding and saw an as you go longer if you go longer you got now get into dangerous on right you get into compliance low complaint zone and dangerous on right so now you need to go to clinic so five days after over thirty thousand people have done the prolonged died we seen very little side effects that are that are there should be reported and and so people can do it you know they don't let me some people of course struggle with it but most people don't and yeah so i think compliance is very important people hate it and if people feel that it was too difficult they're never going to do it again and then you know then it's drugs right so yeah that's that's also in addition to the specific nutrients that you spoke to just by actually hiding people with a little bit of food enhances the compliance dramatically i would imagine now just food but also the selection of food so we big foods for example we have this nut bars and they were designed to really fill you up so it's a kind of fat that after a while you're thinking okay that's it i'm not hungry in the morning is very much but it's made in a way that really makes i mean people again it's not a ton of food but it's.

five days three days
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

01:51 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"For the doctors eventually to say yeah give drugs or maybe i could let the body fix it self right and and see how far you can go with this and then nothing nothing works then maybe we can we can go to the drugs versus go to go into the drugs i and get to the root cause of what's generating this in the first place as opposed to putting a band aid on it so this fasting mamani amendment mimicking diet protocol that you've developed it entails a protocol in which you have these foods and you're on a very strict schedule and the idea is that it allows you to eat rather than just doing a water only fast but yet you still garner the same benefits that you would but you would experience if you were just doing water so we generated out of looking at water fasts originally correct yes and no and now we suspect then we have data that we are about to bob ish that is not just about the lack is also about what we have in the fastest making right so unfortunately i cannot talk about that but it looks like that are multiple components that we have selected that i've actually positive effects i'll give you one for example we have glycerin in the in the in the festival kim died in glycerine turns out to be a byproduct of fat but also is what using luconia genesis to make sugar when the to to feed the brain now if you don't have glycerin the body breaks down muscle right so what are the division and the clinical trial there was no or minimal loss of lean body mass after three cycles fm the and we suspect that for example gristle is.

kim bob ish
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

02:12 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"I jeff wanted levels of three hundred they probably had a very high animal protein right and they responded very very very well we did not follow their diet after but we heard from lots of people and now the on fm has been done by over thirty thousand people so we're starting to collect a lot of data from from people and a lot of people are basically saying it's a slow process but every time i do a cycle i come back and i don't feel like i have to go back to as much meat to go back to as much sugar or as many coffees you know they've they've done something for themselves and so then they you know they they're more enthusiastic about taking care of themselves i would imagine i think so i may also be something about the brain realize in it that you can handle i always think about say running a tank k around the first time you do it you it's very difficult and after that you could probably do it multiple times a year and it doesn't seem that hard i think is realizing that it's okay it's not that hard no you have to have sugar all most people haven't have never gone twenty four hours in their entire life without eating solid food and just the idea that seems so daunting we we we have this notion that will just perish if we do that and to kind of undertake a protocol like that and go to the other side of it and realize like oh that was i did that that was fine makes you rethink the human bodies capabilities yeah absolutely they didn't if you think about for example the brain of around five or so or the md by fifty percent of the fuel counts from bodies right from fat and most people that pathway in the brain is probably never been activated right so somebody could be fifty five years of age and never once has activated these us keep them by these in the brain so then what's wrong with with exploring the keita genyk diet all the time.

jeff fifty five years fifty percent
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

01:49 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"Healthier so they live longer younger and healthier then we did the human clinical trial with this prolonged fasting mimicking diet and we did three cycles once a month five days again vegan five days of this lauding sugar hide good fat diet and and then we give him twenty five days of noricum commission go back and do whatever it is that you always done no exercise recommendation no food no nutritional recommendation and then we measure the effects after a week and three months after the last cycle and i think the results were remarkable saw lower cholesterol brought pressure lower triglycerides lower fasting glucose lower inflammation systemic inflammation as measured by crp and lower jeff one which we believe is there one of the key markers risk factors for but aging and cancer but the interesting thing this happened much more power it was much more powerful and people that had the problem to begin with so if somebody started from an ideal situation they were a lot less changes then somebody started with high levels of this of course of course that's absolutely fascinating was there any were you able to sort of quantify when you said okay go back and eat whatever you were eating where you will wear of the differences in how people were returning to their lifestyles and was there any differentiation amongst that population based upon their just sort of preset lifestyle i mean we knew that again the the people that for example had.

five days twenty five days three months
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

02:00 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"And you know and you have to wonder is this sustainable to is it a compatible without lifespan of one hundred and ten probably not as it wasn't for the monkeys so that's where then you know becky today's i made the fight completely starved year bacteria or a completely starve yeast they live longer and stronger right so longer strong meaning you hit him with toxins nothing they're very strong and baltimore and if you look at bacteria and yeast east as you carry it so they're being separated by hundreds of millions of years so i started thinking is possible that you could do this for every organism and it's going to make a stronger and protective for a long period and that's where a lot of this comes from and so jumping ahead twenty years then is the mouse is that we i did which were what if you take a mouse and you give fast in making that why is it a festive making diet is you know what i was talking earlier about the nutrients determine what genes are activated or not so if you have a certain composition low protein low level certain amino acids and then i have no sugar high carbohydrate below sugar and highfat by good fats right all that you put it together then the response of the system is just like if you give it what it only fast and you just give water and you hit for for four days and then you put them back on a bed diet relatively bad is a vegan so four vegan days for the mice and then ten days of animal based either and then you keep doing this twice a month now we show that the mice live longer about eleven percent longer but the remarkable part is the cancers were reduced by almost fifty percent and and inflammatory diseases were by fifty percent and these mice just their cognitive abilities was was much improved right so they just look younger.

baltimore becky fifty percent eleven percent twenty years four days ten days
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

02:03 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"Tremendous yeah my protein needs on that equation of you know point three two comes out to about between sixty and seventy grams a day it's just it's not that hard like i some almond butter i you know rice and beans i eat lentils and keen wa and things like that it's just eating those foods like i've done the math and it seems it almost takes care of itself like if i'm just eating clean plant based foods close to their natural state so it's not about going out on my way to make sure i'm eating you know tons of garbanzo beans or anything no no no i mean i do that if i saw my diet is planned base five days a week is no problem but i do bay attention i know that a certain amount of sorts of vegetable contains so much and so once you get used to check anything so it's very straightforward i'm just saying that i suspect when the compare say vegans against the numb vegans and they show the vegan doing better in those studies i suspect that's because so many people in the vegan group our nearest and that's why you see these are wise i think the vegans should've been doing much much better than the non vegans if it wasn't for management so if you can turn the vegans into wellnourished vegan then i think we'll see the superiority that we already see in the blue zones and in la melinda etc yeah i think that's a student i mean i think my fear and i think it's a very real fear is that as we continue to produce all of these processed versions of meat and dairy products that are tasting better and better and better the people that are entering into becoming vegan can easily just be eating all sorts of refined grains all the time and cookies and snacks and things like that and they're you know they're like hey i'm vegan it's healthy when in fact it perhaps might even be worse than whatever they were doing before yes absolutely so i think this is why i talk about once you figure out what.

wa la melinda seventy grams five days
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

01:47 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"You know having high saturated fat diet is associated with a lot of cardiovascular problems now if you look go around the world and you look at the centenarian pillar none of them have high fat now the okinawa's not the loma linda now the indians collaborations now the costa ricans and not the people in greece in so yes so then you have to say the animal data doesn't support it that'd be them logical data doesn't support the centenarian data doesn't support it the basic the basic sort of doesn't support it there is really in the clinical randomized clinical study design support it saw you have to say well in thirty years when you have two hundred more studies all supporting this which would be almost impossible because it's all ready so much negative data on so it not not worth it now worth to go in that direction you can do as well by being on a low sugar low starch high carbohydrate diet and is there anything people they like to say bad carb good car right it's about again same as fat it's about sugars and starches pasta bread is not about carbs carbs contained in lagoons and the cubs contains in vegetables are excellent carbs and even the ones starches if you have if you maintain relatively law it's fine it makes your your diet more enjoyable and so if you have fifty grams of pasta rice that's perfectly fine if you have one hundred and twenty grams of that then you start to get into the problems all right so so i think that that these really must start applying is five pillar or an f i bill people are gonna have seven pillars you know whatever they want but certainly.

okinawa greece cubs thirty years twenty grams fifty grams
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

02:15 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"You know like taking exogenous key towns so where do you come down on the keita genyk diet where do you come down on on this this kind of dissension amongst health professionals about this subject yeah i call it zero point five biller strategies right so you come up with a couple of studies showing acute effects let's say you eat lots of butter and after three months you can look at a twenty people and they show like lower cholesterol and the zero point five pillars approach is very dangerous right why is it very dangerous for example if you take mice and you give it a lobe high protein diet right and relatively high fat they actually lose weight and if you stop the study right there you say this is a good diet you know if you continue eventually they've development the bolic diseases and they die early if you give him a low protein diet high carbohydrate diet actually gained a little bit of weight if you stop there you will say a bed better idea if you continue they have less metabolic diseases and they live a longer so why is it problematic than to have zero point five health appeal well because you're gonna get surprise and and so if you look at me many many studies many of which i listed in my book you see that the the low fat avoiding the situation fats over and over and over is a good idea avoid in the unsaturated the olive oil are not successor it's a bad idea so for example the the asterik study in spain thousands of people randomize trial you put health of them on lots of olive oil or lots of nuts every day that had to stop the study because i was an etiquette for the control group not to have the same right but if you look at assisting work and you look at the denomination not just then but lots lots of data you see that.

spain three months
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

02:12 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"Now the world health organization says that so does every other major association i think the national cancer institute dow is usda i think is also now reduced a recommendation on on broad in because of that so red meat particularly is now recognized by almost every major association specializing cancer to be respecter or certainly something that you wanna avoid in monday's you know as you know we had multiple papers we and harvard school bobby published a series of papers all of them in greenman with these idea particularly for red meat budgets also for pro highprotein so after our paper we bob one with adua nutrient harvard and also confirming the plant based diet was protective compared to a variety of diets that included highprotein from from animal sources and what is the active component in meat or red meat that's causing these problems is that the high density of protein is at the hormonal breakdown in it like what can that be drilled down to nobody knows for sure i mean there's a lot of speculations of some of having to do with him content and i've heard different stories and different i pol disease it could be are the fed steroid hormones are they fed antibiotics who knows right what what is in that meat and so probably the combination of high proteins but also older molecules that make it into the meat out there are probably contributing to to make it very clear particularly the red meat seems to be that your mental but in our paper we showed that all the animal high protein diet from from all animals sources were detrimental.

usda bobby harvard school
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

01:43 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"And i'm the first one that will say we're going to have nepi deming of over protein or reading too much in and we're going to find out the consequences very soon i mean in our people who show three to four fold increase in cancer incidents right and seventy five percent increase in overall mortality in the following twenty years for people that were sixty five and blah in even for the sixty five and above it was the moderate protein intake it was not the high didn't need to have high protein intake moderate was sufficient i mean in in my book i talk about maybe increased by twenty percent when you get to agencies vice seventy below the minimum recommended right so yeah absolutely but then again if you look at fish and i have to go with the science and if you look at most studies fish is always on the positive side beside the mercury fish swordfish the tuna etc for all of them but the most that is are showing beneficial effects right that's why i have to say even though some people can argue well at lea may or may not be the best idea but if you look at the science fish plus vegan seems to be the way to go and what is it i think when you haven't sort of said it explicitly but this relationship between meat intake and the incidence of cancer like what is going on there because i think when you say that to somebody like basically saying meet causes cancer is that what you're saying and if it's not if it is if it isn't like i want to kind of clarify that yeah i mean i don't say that.

cancer seventy five percent twenty percent twenty years
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

01:32 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"Really get a pay attention because you you may think something super healthy for you and that's something maybe killing you so you need to find out are you out immune allergic intolerant to something and that's something may be twenty different foods which are all vegetable by the way right so so if you don't remove it you're going to have a problem and you're going to suffer and clear case i always talk about italy in in the electors years i used to go to italy and i said this is really incredible and because ninety percent of the sicilians are lactose intolerant and yet for until five years ago i never seen a coffee shop in sicily the serves a soy milk or almond milk they had the regular milk so i said you know everybody is drinking this must be suffering and so you have a whole you had the whole country there was getting macchiato a lot and they were all cow milk and they must this must contribute it to an epidemic of gusta intestinal disorders they were very obvious because i'm peoper we knew that they were lactose intolerant and yet nobody nothing was done anything on it you know it's pretty funny all right so on this idea of the five pillars let's talk about what we can extract from the research that you've done and what you've learned into some principles that can kind of guide us in the direction of promoting longevity in our own lives like what's most important.

italy sicily milk ninety percent five years
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

01:43 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"Dj and what are the group there are it's called g h r d growth hormone receptor deficient what did they die off in a what age and so a look like at least into dozen eleven there wasn't a single cancer that they we could find either in these one hundred subjects in ecuador nor in the two hundred and fifty subjects there as laurent had been following europe in the middle east out of three hundred and fifty people if fifty years of observation nahla single cancer that now that happened layer probably due to this terrible diet sort on point is jeans are not able to create immunity against cancer but indust far there's been three cases with diabetes again out of the three hundred and fifty or saw subjects which is another extremely law prevalence of diabetes considering that they have a terrible diet a lot of them are being overweight and so yes so then then these mutation in humans seems to be very much behaving like the the mouth mutation which makes them protected from diabetes cancer the mice and also very long live now the longevity we don't see a big effect on jetty there's probably a small effect on jeopardy but we suspect as we know for mice that by having a terrible diet these may be not removing the protection against diseases but removing this record longevity right right right so you deduce from that what and how does that inform like the next chapter well from that we we deduce that.

ecuador laurent europe growth hormone fifty years
"valter longo" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

02:30 min | 3 years ago

"valter longo" Discussed on The Rich Roll Podcast

"But for example upstairs had somebody food you tom annoy and it was working on undress and we feel that described arres reacted or was activated by sugar right so then came out of the welfare lever say sugar activates grass in color restriction extends the lifespan of all these organisms must be that if i delete rests the east they're going to live longer so this is a biased approach versus what i said earlier which is completely unbiased and sure enough now they live longer they'll it three times longer just by deleting sugar gene so now the taurus is gone is is the protein pathway and the big raspy k is the sugar pat way right delete bottom you get far last minute stench well and then you then step it up and and apply this to a rat population yeah then then you apply to another cal case a mouse population also knowing that the data from from cynthia kenyon gary robertson and others in warms and flies right which was matching so everything's starting to make sense there was all align line so tour was causing aging in all these organism issue activated and if you did protein restriction the organism live longer right and so just brought in restriction so yes so then you do the work in mice and then of course you do the work with nutrition and say well if adding if deleting the protein gene and the sugar gene makes organism live longer what if just removed sugar and protests and then you go in providence to say well do i need to remove all products maybe not maybe just sorta amino acids that contain the in so we remove syrian thrown in bali in three amino acids and show that those were the ones that major wanted to control the tour gene right so yes so then we start a really having a much more sophisticated understanding of all the network the controls aging in yeast and mice but also understanding of the nutrients within food the controls the genes that control aging right and then so then with this population of mice these studies that you were conducting how much longer were they living so the the the mouse work was originally done by under a barky and john capture.

arres gary robertson cal cynthia kenyon john