13 Burst results for "Varmus"
"varmus" Discussed on The Kerry Basketball Show
"Yes it needs to get to the dog like it has to get there has to get all the way up the line. Otherwise it's it'll just keep kicking the torch. John we will certainly keep an eye. Hopefully it doesn't get kicked to online to touch at a certain needs to be dealt with particular. Probably next week's john because if this is indeed within the next month or two nubia between for clubs to get going then not january every game video ear and it's like you said you can't really kind of expect a bit longer a year old between heroes longtime compared to personally says semi yet. Say like sorry. My my fear is that to carry company basketball board. Start putting on cook county leagues for under fourteen sixteen eighteen to cock the dope on they stopped playing basketball when kids have been discriminated against and then didn't show it just keeps going on until such time as the golden decided hold on one second. That's an indoor sport again. I don't care vaccinated. it's just shut that. Don't yeah that's me. Fear we have written letters county board asking them not to start competitions here because we're the ones that are going to have to take they can't play and also it's gonna feed into the whole take on the chain of move on with us you have to you know there has to be shut. Don't know where people are just saying. No off the north nets play as normal every kid be discriminated against normal our that we're going to basically take the streets and we're gonna go and ring politicians are gonna keep going up and it gets off chill under. I two outings team tree. Sixty financial clayton were looking to put a salad full game together. They face my colon at clark. Sports complex in rowntree taking on wall street had joe plenty. Promising border defeats the trillion. Belen colleague with needed not to convert that to wins and win. They did will. Well deserve sixteen point win over the galway side. Once again it was thomas who sparked control with this classy to plenty helped to from xabier lonzo and jeremy medina but despite this it was the wayside that lead twenty five twenty four at the end of the fourth quarter. Both sides worked hard in the second quarter with defense is giving little away over medina. Uc's height will produce to blindter on alan thomas his way to a twenty six point game finishing this patient team move despite this grant. Also my colon will in the game. simon francis. mock. Turn for this winning score. When he's on rebound and including much-needed free. What's the amusement of coil cunningham. There were a few minutes of concern from taking was charges as my head pushed over to torture four twenty-six lead midway trump second but a seventeen six pushing the latter stages for the home side saw narrowly hit forty five forty three pointer by francis proving vital clarken and pushed ahead in the tarred. Seventy one. Sixty tree is my collins shooting. Big dessert him while killagane. Continue to find this course. Nita's just fantastic team move finished by player. Coach declan wall just a number of excellent efforts in deterred and by the buzzer. It was colin ahead by sixteen and more importantly showing up on the super league table. Hard earned home. Errand win initial issue. Talk to win the owner second-half renaming truest playing against you need to win followers outside after i got better performance the last two weeks. We cut her as we've done so we kinda training this week there'd be. We don't condone to try and get this force in the boardroom. Skinny a half time scores by tcm. And yeah i suppose we got a trees sway with maybe ten or eleven points kinda hit onto dash. That was important stress leads. You know you needed to get lead. Sorta kinda knock them offered as you kept him at four or five points in game four. Call her in a game with the last minute so we didn't want that saw kinda pull away and it was kind of comfortable last live in superleague wing as talking. I mean district gathering. Yeah i it's all dependent to get your free in. All i suppose to horses toll fixtures on here for saw Yeah we look forward to each nine afternoon. So we've been to another window we can. Yeah we can confusing and went up there with and these players varmus is on the was happy. I will probably be a good defensive team farm and again forced expensively we give up clark d two points so defense units offensively. Didn't we made big shot. Sarah francis in thomas cigarette stretches well some sports positive puzzling..
"varmus" Discussed on Chutando a Escada
"Colm league within tower. Zaki mccabe's thabiso moving. Kiki queens amira touchy wreckage organism clara on filed interference on the cairo. Who contest Nadal clear so now particular asylum teddy or mice g. a. combing according to convince Not me general. Siege kept militarize norma. Having cooler educador did due to delete internal dane. Mckee was his s. Thanks to institutionalize our sonoko to as each built amina falah. Kyoko sake it. It apparently to graduate g the Doing today the super Movie doesn't sell komo. For mainly ronaldo soviets stud near Storebrand main to this two sonatas song key. Chica tacoma bill magical dodgy just see a was co- saito instituions. Oranges started comanche. Clamming shuzhen syjuco airport. this wasn't thing though he political simply What you say. Max weber new lumine executives systematic demos with each comedy Do it sat out blissful same. that video don't drink. Elementary was percentage Blooming masochists. Though don't billy as roma's on montage intricate you go on mine. Discussing spices our dana. wonderful yanni. So why Not giving megyn kelly wonderful shawna illinois much through. So you'll have your my school made me does In fact wedding video now bang luc's does To mysore mission kissed on our Komo linking proposal diddley varmus philology instead of meeting new lincoln restyling martha. Vj new offerings of Boils now florida. Ultra few mikoyan. Jeep catching Each shawna decker genova. Thank you i think. Donald coupo- sisters by told the moves little's but dunk last. Like this don't believe Would you mice but also follow of what's in colorado. A gal not been exploiting your did they know your mood you. Building equal massamilla. His jeep and jubal's arduous etching. He's hit this sobe. Fan who soviet Publiz boggles over. Belli's what his job was. Boggles on jay or going diffusion of not that you love and it is awesome. H that's of you'll lynch quenching nature appeal Mice not awfully call hinge on his belgrade wound. Up give you up. dodgy ancient but loses to maintain ramsey yakamora. Show this For moors ruled that one. The missing old fuming hurts nucleotide bouche Sick died and large. I'm gonna stop elevated avista. Cheever are you should at least up. message kuta this delusional. Cg visual a episodes kazakh usual Goes optional see someplace Equity seasons on this is like siege. You should force was saying argh Vice senate Al constabularies inocente is the bias. By everybody's instilling advice feeling shows up in chapter stores vivas or don't buy vice matches involving Young they move up to. The parliament has so visual mice. Shawna potomac goal himself dish. buddha kid general cj alimony dodging Will as you know elmo fuck will dodge we'll go shoot sick with only Blue group of the super jock checkout all a door. It is is the Man was hotel. Jeeves yelping allergy. Who owned up. And not boys i with a god who Mobile said his intimates. Adecco w Needs you'll seville journals teachers Said dating yeah ain't no vantage immunity since moving through it. The anthems would writing apropos. Body home we stopped the whole he could eat out now. Our sun out he also wooded mamounia That you would nica mushy start the lead up la on also katie. Steiner kitty the meager budget ethnicity. Stop to jehovah lanell surgical system. Who could general ed. But if he's don't Omit ms was insane so specific. It's by this yucky. Group them Let me see members this brutal. A fence gaddafi's. I figured a dodger. Fizzy gay men thoug- lissi blue shoe j. so they show now disag- lupul Feed the people walking through the streets of the bowel paseo imposed. Sonia judas actress Haussas june group spot walks struggle Video doesn't jesus flow. Three d does Device a book. It would kill fiso If you didn't you mentioned Causing those to jehovah any try putting native will now be my nature. They started promoting bad. Just as so the abu off the obstacle meteorological ghetto. Shema nagase occupies. Ask them they if you want me to be here. My spills coffee talks doxa musical mobile gene.
"varmus" Discussed on All Rabbi Yaakov Wolbe Podcasts
"Have the capacity of intellect like an angel and we have these two forces vying for control. What it's what's gonna be what's gonna be destiny. Are we going to be instinctual. Beasts or we're gonna be intellectual creatures and he explains that left our own devices if we do nothing by default will become more and more and more instinctual more and more like animals that is the natural state of progression or regression of mankind. However the almighty doesn't want that the money wants us to upgrade angels and therefore he gave us a tool to sharpen and hone our intellect and thereby augment our intellect and give us a fighting chance to retain erin djelic. Our intellectual have and. That's the torah. That's the primary reason is why we have toro. It's to actually supercharge our mind intellect and make that a more dominant force in our lives. So we're seeing over here. How yes there is a natural distribution of abilities but it can change and he can be expanded. Our intellectual capacity can be expanded via torah study. And therefore we're gonna talk about the four times of students. It's only by younger. Students not by more veteran advanced students. Tom tells us in the book of mosser. Page one. seventy five beasts at the very end of the book of basso harrowed says cheyakh game someone who wants to become wise youssuf within moments should specifically founded the part of the deal financial matters. Why because those parts of the torah are designed the most or necessitate that you have to really set it the more finer subtle and nuanced arguments and that trains your mind to be sharper and more potent. People is wonder you go to yeshiva. Ain't gonna stay torah and the things that you study are almost never relevant to your actual lives. You know we spent a year studying the book of you varmus which deals with leverett marriages. Which is i mean that. I've never seen anyone who has seen it before. So i studying gets.
"varmus" Discussed on KQED Radio
"One thing that happens is the cells lining your intestines secrete a bunch of fluid. That's why you can have diarrhea is all that fluid coming out and those cells can die. But they get replenished really quickly, and the wind pathway actually is what causes that regeneration and replenishment as well. So it's normally active in many places in our body. And then it gets activated either more or if it's somewhat, um, static. It gets activated from the liver, for example, upon injury so that injury causes the gene to be activated. And the gene secretes these proteins that bind to the in the case of liver deliver cells, and that starts this whole pathway. It's referred to as the wind pathway because there are many, many genes that ultimately get turned on. That have to do with making the cell divide making the cell differentiated into a very particular type of cells so it can have that function. We talked about it and have that function of making proteins. Filtering out toxins metabolizing drugs, But it's the injury initially in the liver that causes those genes to be produced. So the this wind process actually goes on in other areas of the body. Yeah, it does. It's a normal what we refer to as a normal physiologic process. It's normally happening. Not all the time and every tissue But in the intestine, it's happening all the time. And all of us like all of us, create an entirely new lining of our intestine every five or six days. The cells lining our intestine get completely replaced in five or six dates. And with the wind pathway is what Stimulates that. So it's active all the time in our intestine, So it's all over the place. Restoring and repairing. Yes, all triggered by either damaged or some something going on. To go in and restore those kids or just a normal Yeah, exactly or or it's just how we're able to just replenish that that tissue or organ like the intestine on just an ongoing basis. Ah, so it keeps us all in. Keeps everything tip top shape. Yes, we need to restore you constantly. Yes, I see it. So in the field, people refer to this as So we've been talking about tissue repair adult tissue repair, and people refer to that maintenance function as tissue homeostasis or maintaining the organ in its state. Can people not have this process or have a whole lot of it or how does it work is that they're very it's here. There are mean like, Like many genes and pathways, there can be mutations. And in fact the role of this pathway in the bone, so it's active in the bone as well. We know that it's critical for bone formation. And there are mutations in this pathway that our bones specific It can cause people to have either osteoporosis like disease if the pathways not active enough or too dense a bone if the pathway is too active. So there are there are multiple, um, mutations that are known in this pathway. There aren't a lot. It's such a critical pathway that you would be unlikely to be viable. Um, if you had multiple mutations in this pathway because it's really, really important during embryonic development. So, like many embryonic development early two genes, If you get mutations, you just don't develop as an embryo. Now. You said that we while we know about it, we don't know a lot about it. Is this very new? Our knowledge of it? Well, we know quite a bit about the wind pathway itself, Um The many other contributing growth factors and pathways to the whole Oregon regenerating. We don't understand all of that. But the wind pathway we understand quite well and it has a fascinating history. Actually, it will be 40 years next year that the wind gene was discovered. And it was discovered by Harold Varmus, who later won a Nobel Prize. He actually describes this gene in his Nobel lecture in 1989 and then post doctoral fellow in his lab. Rule Noosa. Was a founder of Sarazen. Um, co discovered the gene and he's been working on understanding this for 39 years now. So there is quite a complete understanding of what these proteins look like how they function, the other genes that they activate which tissues their relevant in But despite that long, really incredible history. They're still new cells being identified in new tissues being identified where this pathway has relevance. In the lung, For example, there was just a publication in 2018 for the first time. Identified cells in the basically the air sacs in the lung that can respond to this pathway and replenish the cells that make the light these little air sacs in the long they're called LV alive. So what's Sarasin doing A. So what we're trying to do is copy that normal regenerative function. But in a very targeted way and just for damaged tissue. So that process that you know we've been talking about with alcohol injury. Those patients don't have an active enough went pathway or went signaling to keep up with the damage, So we want to enhance it, but we only want to enhance it in the liver. An inflammatory bowel disease patient. Potentially if you could cause that lining of the intestine to be replenished more quickly. You could overcome the ongoing damaged from the inflammation in the lung. Smokers have damage to these air sacs and again, theoretically, because we haven't studied that yet in an animal model. The recent discovery, But theoretically, if we could stimulate this regeneration only in the long we only want to targeted and the disease. Then we can get that kind of regeneration. That's not happening adequately, and it's that targeted part. It's a very unique aspect to it, sir, is it does So anywhere the went gene or the went proteins are active to have a restorative or or repair mechanism. That's where ultimately you want to go. I yes, and I would say exactly and Where they're not. They may be active, but they're not active enough in responding to injury, right, So we want to enhance their activity in that injured tissue. So what's first step Well, the first step is, you know the way I like to describe this is we're standing on the shoulders of the 40 years or 39 years of discovery and understanding of how important this pathway is in different tissues. So I mentioned bone. We also started out in liver and intestine because there was this extensive knowledge. The pathway being important in those tissues. So that's where we are. Starting point is, Is there good information that this tissue can be restored? That it has regenerative properties? Meaning is the wind pathway there. Is it potentially can potentially be activated in that tissue, and then we ask ourselves, okay. Are there important diseases and those tissues where, theoretically, if you could make new cells or improve the function of that tissue, it would have a clinical benefit for patients. And we sort of bring together this understanding of the biology, this ability to make molecules in our case there antibodies that act like wind proteins, but only in a specific way for that tissue..
"varmus" Discussed on Discover Music Channel (Discover Music Channel)
"You on into the one and only guy live right here on. Discover music channel play man today in today's played mass segment. We have all the way from the commas shine to four to raking scrape artists. Sean welcome to the show that you joining us. Thank you love me sign You know. I know that you are raking scrape artists. Out of all of the genres that you could have picked. Why did you choose to become a rake and scrape wind. It's like what inspired you to do. Raking scrape one. I live in a varmus to You know that's basically all. I knew especially being on the defense was balking. Most of the reagan scrape artists in the bahamas. Falkoner them in the defense loss bond on also in synergy so it was just kind of like almost embedded in me in daybreak so tell us a little bit about yet his relate where where does your love for music come from. How did you get involved with the different bands that you've been a part of and how long been doing this. I've been doing this sense of the no myself. I could say like about six at the age of six guy. Got into like minority. Bon john canoe. And i've been in not for a while. And then i joined the defense for us and i served in that department the bond department filling on various rules such as Keyboards playing trumbull trombone. The baritone saxophone and I was a drum major for eight years putting in like the beat retreats together so i always had a love for music but i realized that it was like a gap in the industry in of reagan scrape. I just took a bet on my salesman. I always interested in being an artist. But i didn't really know how to get there or how to go about it and i kind of figured it out and i'm here now. So how did you go about it like what was. What was the first thing that you did to the. What was the first thing that you didn't to be a solo artists. Like you say. I was like i said i was offense bond for ten years and then i recently joined synergy bond a few years and like i said i realized it was a big gap in the industry in terms of ours. That you gotta call on two hands literally. Homage artists use Get jobs or beyond shows. And i realized it was a gap and say you know. Maybe i should try it. And i mean to see like what happened. I did that. Because i think it was only at one. Point was mark Just run into san for a few years now. Cillizza talk guy but it wasn't really anybody off them really shake things right so like mother the songs that you will got you. What was the song that got you from behind keyboards drums to the microphone. The song would feel like wine. And i was actually the first song i actually does occur single that i drop Now is the league wine. And i want. Yeah so i dropped. And i dropped a february on my birthday. Every nineteen two thousand nineteen for every eight. Two thousand nine hundred. Sorry birdie and i didn't know where it was going to go in. I mean. I just put it out there on. My song was about three years old. Before i even put it out to be honest i was trying to find the right production on it. You know and. I was pleased with i so i got it read it. I know they're two thousand. Nineteen every two thousand nineteen. I would say it didn't really take off until maybe make all the different video stations. Like reaching out to me these you know. He's beaten on new behemoth artists museum in music for a very very very long time. That kind of gave me the inspiration to Do more for it was like mine for a song option that i put out there and it it put me on the up so with with feel like whining and having that having that touch of success in and seeing the reception that you got from it. What did that do for you as an artist. How did that. How did that help spark the rest of your musical. Sound right Yeah like. I got good feedback from feeling whining and in i always was studying industry and best internationally on here. In the bahamas. Also i like always looking at what to do what. I shouldn't do asking certain questions to get me to try figure out you know 'cause you know the culture is really telling you that if you are being in saying that you know so you know i i put myself out there I just didn't want to be a one hit. I put i put myself out there and i. I told one of the guys who in charge of ronald sims. I think is his name. Rana sims i. Toil says they have a song. Now you say are you. Are you have a oh debt. And that question actually sparked something for me is will use the odyssey need more catalogue janice one song you know especially if you wanna get on Big jobs such as regardless or whatever music festival whom coming trying to have you know You say you need more catalog and it was just after that. It was just pure catalog sense then to now learn how to produce myself. I've collab- with artists such as demob rick. Perry benji just gaining information and knowledge from them. And actually you know trying to transform myself into an atop artist now when he say a top artists. Are you talking about a top. The heyman artists traveling throughout the seven hundred islands. Are you talking about a top caribbean. Bahamian artists traveling throughout the world representing the two for two. I'm talking about doing that. Well you know the second option. Of course you know sometimes it. It's not recognizing down. You know now cultural. They like you and they don't like iraq but you know we have literally i tell people world mall now because we have it in the palm of our hands you know and in.
"varmus" Discussed on Clear+Vivid with Alan Alda
"On to head department. And exactly i mean the nobel prize assists the tippy tippy tip of the iceberg. I mean i'm telling you in my generation virtually anybody who was a professor of medicine or a dean or ahead of a medical center. Everybody came out of that program. And what did they produce in terms of the ability to improve people's health and save lives. I mean when you think about one third of medications involved in receptors that you worked on that you were so let me get. Let me a millions of people. Well let me let me give you a stunning example. Let's take the four of us from the class of sixty eight to seventy. Okay yeah so we talked about my own research and a third of all drugs herald. Vomit discovered the first oncogene the first cancer causing gene together with a a research partner. Michael bishop who was also yellow beret also nobel prize winner but to three before varmus. Okay so a third of all medicines for my receptors varmus Oncogenes cancer causing genes has led to the ultimately the entire revolution of drugs. That we have. Now you know that treat The mutant genes that he and then otherwise discovered. Then brown goldstein. Statins cancer heart disease. And then of course receptor drugs like you know having heart disease and diabetes and hypertension just everything so just from that one class. What an amazing yield That millions of life millions of lives far. Yes so far exactly. And that's just from that one class Doesn't mention all the other stuff in the immunology and it's just aids and yeah it's interesting. It's sad that this couldn't be understood. At the time that people who use the term yellow beret as a term of opprobrium as a way to call you. Cowards that you orange serving your country saving the country. That's that's very wonderful perspective. And in hindsight of whatever forty years fifty is Very true did you. All at the time have an awareness of what you work would lead to did you. Did you have a a glow about you. That i'm doing an important stuff here. Absolutely not you shaking your head before you today right. I thought it was gonna be a big yet. Because i think back on it and i think of of just how far we were in our consciousness from any appreciation there. We're learning something and Once it started working it was a lot of fun And i think you know. Even by the time i finished there i was thinking. Well you know this is probably going to affect my career. I i may be heading in a different direction. I wasn't sure yet. I may be heading in a different direction but the idea of what would come from it. Not even close. I mean there was no awareness for what what propelled you aside from this awareness as a physician that you might be onto something that could be valuable. There's that other thing that researchers tell me all the time the notion that you are now in possession of knowledge of view of nature. The nobody in the world has ever seen before so true so very true and it doesn't have to be a nobel prize winning discovery. I can remember when i was at the bench myself. Which i haven't been many years and i the end of the day. I would stand at the simulation counter machine accounts radio-activity different vials. So i'm actually seeing in real time now. The result of the experiment. That i've done today before i go home Not the final result but the preliminary result. And i would see this happened. That went up. Went down and i would know in that moment. There's no other human being who knows 'cause nobody exactly that stupid little tiny increment of information and it's yeah that thought would actually occur to you. Yeah so interesting. Yeah i mean. And i think what you said is true. I think the scientists because that's the every experiment a little discovery. And i always try to tell my students. My fellows have never. Could it be true with it. You know they talk about. It's the journey not the destination. Yes i if you're waiting in until you solve the big problem it's going to be a long way. But if every little experiment even when an experiment fails it can teach a lot but everyone is a little discovery. And that's what keeps you afloat from day to day even when you don't seem to be making progress just every day home with little little extra nugget of information. The importance of that little nugget of information became vividly apparent to bob when he left the nih program to pursue the career. He thought he was preparing for as working physician. In one thousand nine hundred seventy he went to massachusetts general hospital to do a senior residency in cardiology. The first six months were all intense. Clinical work and i liked it. I liked it. I didn't love it the way used to. But that's when i realized something was missing. And what was that data. I had no dade. I've gotten used to having data every day. Good bad or different in other words. The scientific process was missing I would go home at night. Not having a new experiment that think about not having a problem that i was working on and i really missed it. And that was the first inkling that wait a minute. I'm going to need to get back into a laboratory to at least have part of my career I'm part of my thinking. Engaged with a scientific problem really were transformed exactly. I didn't realize it. Even at the time i left the nih I remember my mentor. Saying you can't leave. Bob problem you making real headways and now i mean realizes who's fun at the end and at work and we published a few papers. I said but i'm going off to pursue what i always dreamed of but then when i got back into it i realized something is missing and i realized what it was So that was a transformation that transformation and continue over the next few years It would probably take me another five to eight years to become fully. Let's say five years to fully embrace that. But what i realized is the i had another calling. I remember talking. Not that long ago to a student group i give them a talk about my career and i titled a tale of two callings because i had the calling to clinical medicine but then i had the calling research. I mean and by calling me something. You don't think about it. It's not a rational thing you just no. I meant to do this. Whatever this is. And yeah so.
"varmus" Discussed on Recorte Verbal Podcast
"This'll accu ellen. Power system banking's head cautious about who say educated subaru because it's dodgy like thick ave to the south of the same knowledge for my son professor Inching well well jack. Those then yellow so professor on very much. That outlook on chains him wanting to talk about separate sensitive. This will say that he always Now abic luda velocity made said fathi. Was that edginess younger staff. I i go the global. Say tiffany Mind he said just say apple ourselves School knows things. They failed people's as line against a vast learn ship on. Also think nobody gather the united sergio exponential his database keys For muslims professional linguists innocent chievo. And also i'll ask. Mrs hit all those days photo. Bayside he'll you biscuits outlawed is embedded sounds aimed promo abi egypt guy just Those you seen for. Muslims professor julian goes in tablespoon nichols. Ono is not also Interface keys they'll towing seeing the dodge Visit seattle it them being opened your eyes by for my son kunshan either. He got on leptin. When i mean back friday Thanks lingers in also his his young ma'am ultimate example classified ads Bay organza this shipping. Or is she. What i believe is a door. This is sort of considered either link act soak episodes leeming maze like unocal. Who's that wagon day on with. Slasher that out also with open cheese yet i ema ripple punchy vs represented. That amazon was that bullet was congratulate. Saddam stores with face those abilities. And ish advant homing guiding you get anisimov As they batches name he would say fancy subduing did he would say so. This'll be seemingly the gamma had he nicer them. This advantage managed admit he flicks choice Ban on oil school is. Can i listen to spain sas moscow car. We seem janine with a you with all the Facing because we gather boy van classify conveying when does not Isadora moschetti this because outdoor says he faded they now went to was the Vamp before demise zeke leeann bissau's speed see they subodh use to be made chievo losing by family moi coys she. I nest is the face and was vice. Workshop they will pass demata so mass. Sima the joe allegria poses professors zad massive look seeing the inches demise. It easing age. She facilities oil On purpose threes Official the may. I say may he apple semaj fac was be skis. Nottage muscles saudis. At brazil's losing contestants for massoni seattle et. Rosetta made biscuits doors stone added onto damn. Yes novel guy Outside a sorted this call when he's vow who bleaker Nicholas amazon. That is saying. Don't pat on says he's hosanna pass There punching holes halsey awfully as varmus kunshan la sambath. Roseanne ledge poisonous. Society as net was not This calls bilad ban on also. Not is though beget a godless mosquito. Am wash advance. We ought to school soy's..
"varmus" Discussed on Off The Meatrack Chainz New York Podcast
"Had no brandy. I heard of it. But i'm not sure what the color of it looks like. Browns brandy is brown. You make a nice little tickle you know whiskey or brandy. It's not like that. Take a low shot. You know money's so is the is the code is the code of britney is a darker than hannie. I'll is around it. Sounds like it's darker than hanging hainault ways. Ada hemi henny has like a dark color. And i think breath yet. Any kayak right texas got somebody some somebody on on Not right now though. I seem calm cool. But we're going to get it. Get it a comstock but yeah. What'd you calling. I've calling a corner in any or two different liquors. i don't think i've got the version of cognac. I believe. Would you be laugh while be left has a little a little technical difficulties. Let me continue. Where i left off with the whole depression mental health subject. Although the pressure game happened man now you can hear me. Didn't know where you go. Because i see face. Mona sign yet. Hit me missing. I'm a nisit amine everywhere. Dan mean. I'll listen up everywhere you know. My nickname is the l. o. Heen guy the guy. I'm listen everywhere. Sit let me start message. Oh shit oh shit. I was a good one man. So the sediments goes like this feelings. Sadness tearfulness emptiness or hopelessness hold. God agri alpers Irritability ever ability. Excuse me mean butch that frustration even over small matters loss of interest or pleasure in most or or normal activities such as sex day hobbies or sports sleep disturbances insomnia or sleeping too much tiredness and lack of energy so even small task take extra the cove it. that's all like cova symptoms. Yeah cali would happen with with with one with the madonna in the pfizer to Stringer how long the home on the side effects. Last though is a temporary which is more. No it's like a couple of days. Now you'd be you'd be good couple days a couple days talking seven days follow a couple of days two days there. Okay yeah yeah man. The only reason why. I only brought that up because i was a little concerned about her on the side effects is gonna be. 'cause alternate asked my doctor about this shit to adopted a daily take. That day of stocktake. Dick year man. But you know. I tried to explain to my mother like two days ago. And she basically believes all the conspiracy theories and stuff like that basically. Cdc's like like corrupt but how corrupt if they've been studying that when they study everything especially disease in how how operates stuff Multiplies stuff like that. If it wasn't for the scientists we wouldn't have learned about science school non me and argument. I like to bring up against these police officers and police officers that one retire. Just because they received in flack from the media and everything. The same thing happens with doctors with this. Whole corona virus thing with the doctors did the same thing at the police officers dead and say well. I'm not doing my work anymore. Since the people making off for me do my job would have dot the foul. She just quit with a forty people. working on. vaccines is quit. Where would america be right now. We'll be the world be. You felt me. Yeah that's another time. A main main eighth ouchi gene is eighty hughes from brooklyn to local. You can't tell by the way we got that accent. Yeah am giuliani Who else cuomo all. Gaas trump from the local area man man. I don't really care. Man by antibody h get on. He tried to get on he to get on social media and facebook wasn't happy they want be lebron until them out. The cops saying double standards sticking up for trump's rights but then they shouldn't all lebron speaking up about that case with the girl with the knife he was wrong but how many things trump world war with the with the part they said you're next was at raunchy as long as like when purrs says you're next on twitter is sounds like a threat like you making a threat. You know what i'm saying threatened country jennings yeah. He incited the Varmus is when i'm sticking up for his rights like don't silence him. Don't cancel them but lebron has to twitter. Kissel is on saying you've got people sticking up for his rights. That's the point. I'm saying that those same people that sticking up for trump writes us talking about being lebron. That's that's the issue. Making trump was wrong. Lebron was rock but one group sticking up for trump for being wrong supporters. And this is what. I'm saying but those same supporters are hypocrites because when lebron comes out and say something that they don't agree with still wrong they wanna casselman. That's the point i'm making..
"varmus" Discussed on RFK Refugees Podcast
"Dollars here for the month of april will be entered in If you're already a patriot and you get someone else to join. Tell us going to another entry And i think that's all the permutations That that that exists. But that's what we're doing so make sure you sign up we're gonna give this a shot. See if see if anybody wants to do this and we're going to keep doing this for so long as it's a successful so that's this one so enter. Just there will be. There'll be posted on our website but you can basically just go to patriot. Dot com slash. Rfk refugees sign up at the five dollar tier. Enter to win this. And we'll draw on our first show of may which i believe is may third may third so that sleep next one at grad have more things. I have one more thing so if you saw our video today the the preorders for the rfk refugees scarf varmus united on the front or the back. i guess depending on what you're holding it and then The great rfk stadium on the back with our logo have arrived clearly. I have started fulfilling all of our preorders if you want one There are there are some left so please go onto our website. Rfk refugees dot com on the right hand side. There should be a link to buy Now no longer preorder. Just regular order Scarfs so they came out really well. I like them a lot of good quality. They came all the way from bishop to turkey. So that's cool come to bishop dennis senator jerseys And we'll get those out to you as soon as i really post office. I got goal of envelopes over here to mail. So i am. That's now that's me now. I'm the guy that goes to the The post office fifty seven things and everyone behind him gets mad. That's that's me now. But that's all that's that your scarf. Minute online argue refugees. I have an ad hoc contest and going to add to this is greens arches knows onto okay so if you purchase one of our scarves and you are shown on on. Tv i need you to be on. Abc sports washington holding up one of the scarves. As-as vomits united. You find it screen cabinet you send it to me When i go to ati field which i'm sure will be at some point You guys you will you will. You will get a beer from me. You will get beer for me so I the first person who does that first person who does that So that that. That's my little by little contest a little contest seminar before we go to the main event here Of the of the show. I just want to mention that. We have had multiple comments and supportive. Green sauce greg. Koch green sauce fan Jonathan m that's a joke. But he also i think probably likes the green sauce and then dan ducwitz with me while i was doing this doing the said crime also also understanding about the green saw. So we're got another one From asthmatic ten on twitch. So i really believe that..
"varmus" Discussed on Discover Music Channel (Discover Music Channel)
"I'm sorry we can go down the list of what you owe god by. What does that mean. Is that as creepy as hell seriously. What is so. Let me tell. A story lines weights is of me getting catfish cashed. This was in twenty thirteen. Wouldn't be the first time i got catfish. Twice in life is in two thousand thirteen. I'm you know my ex. And i we broke up twenty thousand twenty thirteen game round. You know i Everybody knows tag. They went on tight Central back to amazing girls and say all right. This is good. This is up the first laam clammed at an latisha gibson older than me We spoke on the phone several days but her thing was. She did not have a camera for and she had never formed that connected to the internet so he couldn't video car she couldn't send pictures on all. Its i live in alabama. She lived in freeport bahamas so she tell me some things that would freak bought but obviously email. I have never seen up. I ask you like a come over or let me come over to you but it never worked out I miscarried would've liked to have phone sex rich. I indulged in. You know i what listening to not listening to not indulged him. But i pretended indulgent us. Sake is you know. I my way of thinking was let me just play along. Just keep wild so actually comes over. We could be solid. Not knowing mrs you know a catfish So he'd get to know each other someone. I i really started lakers. Cool conversation everything. I might she he. She apparently new wanted a manages. The hotel i work that on full life of me ain't never arts. This monitor like by you know this lady. Whatever reason Yeah was the first. Catfish are very interesting so xm. Hey ladies and gentleman. Donnie thornberry water i guess the next catfish This girl red saticoy titanium was red. Sun won't call government guest. Somebody knows her but she was very beautiful. Almost a mock hewlett looking like she was a foreign girl but was she I knew she was in. She had the cable amish remote in one picture says she took. I said all right this real so we will talk on just like the necks carolina. She would send me pictures obviously Cool role she used to live with houston avenue west side island. One time we were supposed to meet up she's had location amita Get my cousin. Gargle mita draw. While i didn't change my four size fallen an occasion. A sudden. my phone died. Couldn't meet girl. No ma desperately try and find location like try november two of my head. I couldn't I want i went. She wouldn't seminar location anymore. So i was monitored. And i don't know like if she samuel frequently case you know she said. I missed my chance. It would have league as me but our sermon next couple of years she. I'm aaron to like fis of cops for cop. Had you on an errand to find you never met had you on the air at fine cop parts cop and obviously a had no. I didn't refuse because i wanted to. Mugabe bro So i you good. Shoes blended star filed. A cop is and i. You know related information dog on after we hung up like a click. I wanna listen. I never see the scared. What's i immediately call. Bach like mentally it up. I cuss haute cosso legged. Dr low I get ahead hurt awakes. As us like. Wow mookie. oh. I can't believe you like why would you chris. I that you forget. Even senate location clause is not my father. Jabari died she saw talking we are. I would never know shoes a real or not so. don't feel about overt split. Make a lot of years later eight years. I've been there before. I mean but of course i was way more rootless than you but beth detail. I never told you. tell it now. We're more realistic. Deliver mother to i keep telling people i'm a monster what i am not a nice guy thanks to show. I am not a nice guy. Let's distinct understood here when it comes down to lunch. I do you deal. What a monster. I i finally funnest thing on my. I thought it was image. Turns out hulu with long texting and it goes vaccination by us. Labor director warns business against wants businesses against mine. Matori vaccination policies director of labor john penn. Doug aso varmus director of john Says yesterday that his department received numerous complaints and enquiries from associates of sushi rotan after the restaurant all be over privilege what bay center reportedly advised associates of a new monitory cloven nineteen vaccination policy effective immediately. I dole eyewitness news nobody is mandated to take you voluntarily. Decide whether you are going to take thought or not notify you keep on calling it. That's no employer has the right to force any employees to take any vaccination. That's not law and the competent. The and but bozo did not make that a part of the emergency on us so no employer has the right to force any employees to do that. 'cause it again. He continued. I have been receiving calls from employers for more than that establishment not establishment about two other establishments they are saying that the employers are trying to make them trying to make it mandatory for them to take the vaccine or they can't return to work now. The employer has a right to hold you in furlough until thirty days after the expiration of the emergency orders. Now after that they go after the got to bring you back to work. I am heard. Some employees will force you to pay for your own protest. I have no problem with that. But they cannot make mandatory for you to take the vaccine. And up as i in a letter to the staff title monetary vaccination policy my you holdings ltd the company operating as sushi roe. Conn said all employees are required to get vaccinated no later than june thirtieth twenty twenty one management noted that failure to comply with the monetary vaccination policy may lead to disciplinary action being taken outside and realize that the employees were children Which could result in dismissal or very lease a reassignment to another position lies dismissal if such can be found minimizing direct and proximate contact with the public sushi roku on our the duty to provide and maintain a safe workspace grad the letter. We are adopting this party to safeguard the health of our employees and their families. Nigga is not up to you.
"varmus" Discussed on Amazing FBA
"Unless you educate people to know like entrust you and this comes back to. I'm saying about concentrating. On building your brand overall rather than talking about getting swept up in an obsessing over little tricks to rank for different keywords on amazon right when you teach people to know like entrust you as as as perhaps face of your brand or more more generally your brand than they will buy from you right. Nobody's gonna you know it's the classic nobody's gonna marry you on the first date. Similarly people might not buy from the first time they hear from you but as they get to know like entrust you and understand that you are an authority on that topic and therefore your products are likely to be high quality than they will buy from you so you have to build it and then educate if you just build it. Some people will come but probably not many though two things that. Come off the bucket audience. I mean how do you educate people in create yourself thirty. Obviously for those who primarily sell varmus. Even though absolutely point taking business side amazon's always yours and there's tension that's another topic but let's say okay you real. You got a business building brand but you primarily selling amazon. As as i believe you did if we need to talk about that but how did you then create that connection to what is very much an ever increasing the amazon's customers not customers yet. So you do a couple things you have to have as well as just being on amazon you need to have families and presence so you gotta have your own website anyway. I believe to get brand registered. Certainly used to. I mean obviously you need your trademarks with. Brian registered to bono. But certainly having your own website as an authority of your brand will will certainly help with that. You have your own website from the need to have associated social media accounts facebook instagram. Maybe twitter although it's kind of dying from a brand point of view youtube tiktok now pinterest if you're that type of brand if you're an arts and crafts brun for instance a great place to be on those places. You will position yourself as an authority an authority on.
"varmus" Discussed on Chelsea Mike'd Up
"It's a new day. And chelsea f c usher in the thomas to cool era against wolves and draw nil. Nil chris winning him. And i will guide you through what happened. And we'll talk to ben lyttleton who's interviewed the new man in charge over chelsea several times for his books. It can provide some good insight as to what chelsea supporters can expect from thomas to court. Look on the emotional one. It's been an emotional time. The sacking the franklin part of the hiring of thomas to the drug against wolves. We will talk it out. We will heal. We will get better. We will be patient and we'll saab some all on this week's episode of chelsea miked up varmus absurd swag emotional hosts mike.
The 30 Year Quest To Tame The 'Wily' Cancer Gene
"The time it was just video another acronym another medical term it turns out ross is the driving force in about thirty percent of all cancers a million cancer deaths each year and no drug can target this mutation at least not yet and peers richard harris picks up the story rafts is the very first human cancer gene ever discovered it also turns out to be amazingly common but so a major player in lung cancer and the major driver of pancratic cancer and also metric my own in phnom colon cancer and many other kansas as well frank mccormick was working at a small biotech company in the san francisco bay area back in the early 1980's when this cancer gene was identified and he convinced his company to look for drugs and tests to combat we took off from the so big got into the game and made a few eddie discoveries and fell in love with a whole project long time ago the healthy grass gene instructs the cell to make a protein that is basically an onoff switch the tells living cells wind to start dividing but encounter sells these which is basically defectors or stuck in the on state most of the time so cells just keep on dividing in forming tumors given the genes central role in cancer many drug companies jumped into the fray to develop drugs to fix this broken switch mccormick says people got into the drugs the regain very early for farrah's they tried and failed very early also so people moved away from wrath of the target it got the moniker undrinkable because we've been working on it for thirty five years and so far we don't have a dragon a clinic that works adrian cox at the university of north carolina has also spent her entire career working on rafts she says the failure to come up with a drug is not for lack of crying and speak has rats is a wily beast it's been described variously as a greasy ball meaning there is no good pockets to stick and drug into that's how other targeted cancer drugs work the gym up the works and kill the cancer cells but drug companies couldn't find a drug that would stick to this greasy ball then about four years ago that then head of the national cancer institute harold varmus decided.