18 Burst results for "Trowbridge"
"trowbridge" Discussed on Dental Leaders Podcast
"What you think. I can change here. I'm not one of the things. I see or comment on that note. The really good but they are not match but one straight. Ones ryan's are now for your. I'll meet hard anything until you have some experience doing not knowing wine they don't right because you put your copper on like well and the same wit wi one of wandered and the other so. I think i'm just practices. I guess we'll get you there. I've been a big share. Actually doing this. But i put a picture over congress in case i did about three years ago. Earnings to bomb moment and the post aimed dots young dentist message may asking no of course it should i do you know i always advise the courses. I think are really good namely men's mommy makeover and undies manex. Greg box can do many courses in the world unless you start doing viruses posted. My might one for four years ago in one nine is the. I've done one or two courses between here here and here. But i mean it's just a says. I didn't honored me the patient first cakes message meaning Using using as body alker off. He got her redid. The best of advice you've ever been given. I think there's nothing to do with cynical dentistry and i think it is old to handle and manage asians speaks to. Your patients was thinking agents hoppy if they were treated well on. They may combat General ons isn't won't be it won't change it but as long as your understanding and you're empathetic towards them. You know box may times. They want to get their teeth to place. Whereas i think any an astound office. No hostility between you and your patients. They are much more inclined complaints in it for it to be much more difficult for you than something that you got on with. So i think i think how showing and the thing is probably the best given. I mean since. I've stopped practicing ten years ago. And when i when i think back on my dental career i were even though the ice love fat piece talking to patients and understanding you they are. I still think i could have done more from that perspective. That's really his even now. You know friends and family. Having operations the surgeons bedside manner is just as important as his reputation he does and with us with such a close relationship the absolutely agreement we end these things with profit final questions. You a fan of this podcast but if you were you'd be prepared for perhaps final questions. I'm just in general for us right now. Profit go slaney. Imagine it was your last day on the planet and you're surrounded by once he loved ones who would not be so little anymore and he had to leave them with three pieces of wisdom or three pieces of life advice. what would they be. I was hoping for desert island dish would have holland darn and the start with that while you think about this was gone gone. We'll show what would be your desert on this for my my happy. Long bandits rather be close one day in a place in my mind on in thailand with some powell's and just sit with somebody. I've been trying to do raises are really done on a good night mike. Four in undergrad. I have night. You're earns in old school pre ear odds wire you know older. Microbes are not saw on as like his grade. My three pieces of wisdom or my children on lineup young. I've been confidence in. They are whoever they own are. Not just thing. Insecurity is one of the worst most debilitating things can have so. Imagine a how you turn that into. Words of wisdom of the dinka does thoughts. I wish for the you. One of the most confident people. I've known slaney. Do you think that was. That's something inherent in you. What you get something. Your parents did to me. Inherently i think when i was a child i think my el- distortion risk quite like me. And the child. She's just. Mary are going wants to chat to everybody. There's just newstalk one and a half. No thought but i hope i hope he's always like that. I mean me versus. My sister and my sister is much more introverted than i am. On was more timid. Shy tires wasn't so. I think i think not was era law so be confident not be kind just think there are people out there who are not car but yeah. I just think you were a happier person. He truth pico row. I think having. I fainting Both of you probably know the story to. But i did a lot with an old cleaning her nana jerry. I guess in dawson while ago on quite cross five on. I remember thinking remarkable things about. It's thinking this because he's always just so unhappy it was. Actually you know what i was doing i was doing. The meditation course rammed me and they were getting you think. Nice things about the nice though. It's about people that were different device amendment. You think nice those that somebody in disliked and this is my edge on the horrible full subversion trowbridge. They i just want her. Why i'm thinking like he's our I need horrible in an iser person. We thinking mice voles about him just makes me think that he's just an unhappy person so i think being kind and thinking felt nauseous just no disliking people dislike equal rights limiting it arena really hard cranston your calls like just just leave it at that. I the third yourself behind cardi hard shorts to take too seriously bruin. A slovenly and enslaving. How would you like to be remembered. slaney was taught. How would you you ari. How would i like to be remembered. I would like to be remembered on. The deed worked hard.
"trowbridge" Discussed on The Stem Cell Podcast
"Sorry i mean. That would've saved me like a lot of weekends aroon. I spent a lot of time. Going blind counting colonies. Gosh the kids these days. I don't know what it took to get to this point but I know one person who does. And that's dr jennifer trowbridge. She's taken a long although high road. You would think that she didn't have much trouble getting here with all outside success but it hasn't been easy people. Let's hear from her right now. all right. my fellow does this episode. we have with us a special guest. Dr jennifer trowbridge who is associate professor at the jackson laboratory also adjunct faculty at tufts wishes. They get their grad students and post docs in case you were wondering. They just started joint program in genetics. And the first md phd cohort is coming soon. Jan has got a ton of grant money. So all you trainees out there You may want to look into that. But getting on with the show. Dr trowbridge research is the regulation of stem cells in the blood in normal development aging and leuke transformation her labs ultimate goal is to reveal epa genetic patterns and processes that are uniquely deregulated during aging and or transformation which can be used identify novel biomarkers of disease and targets for development of therapeutics dr trowbridge. Thanks so much for joining us. Show today thank you for having made supply to be here. Thanks for being here. Dr trowbridge and bliss jump right into so. Let's start off by discussing your labs really recent self stem cell labor. Which i think is super exciting. Actually showed that a decline in. Igf one in the bone. Marrow bone marrow micro environment is initiating aging adequate ex-team cells. And this is something that we've talked about a decent amount of show stem cell aging and wastes to reverse it. It's become pretty major topic as of late and even caught the attention of the general public in some circumstances rights. We have to cover it up paper a few weeks ago that was focusing on the importance of another growth factor in regulating aging. But here you actually showed that. It's the micro environment that's really critical in regulating the aging process of. Hfc's and in some situations you can even reverse that aging process in aging phenotype by kind of manipulating jiggling right. So let's talk a little bit about this work and how we might be able to even harness some of these mechanisms to reverse hse aging. Yeah thanks for that. Question of this was work that we really started out in in china. Take a step back and think about the process of stem cell aging in the context of poetic system. And what was known at the time. And you know we started this work. Six seven years ago mrs long-haul projects and when we first started the work week we quickly realized that it. Most of the literature had done a binary comparison between young and old individuals. And we thought. That doesn't really tell us while that tells us a lot about the biology that's relevant to extreme aging well. It doesn't really give us any sense of the dynamics and we also had in the back of our minds to sort of chicken and egg question. What ages i this stem cells or the environment And and so we had planned out a way back then are a couple of different studies..
"trowbridge" Discussed on The Stem Cell Podcast
"And then finally Are tandis group they showed that in clinically relevant context and actual human neoplasms of the pancreas. You see that there are these rare ace inner cells that are fossils positive so it looks like they're in the midst of this malignant transformation involving so all in all think it's really drilling down on. What's the cell origin of physiological. Renewal within the pancreas. But i think more importantly about how you get this. Clone expansion in the context of care asked mutation and turn expression That leads to this malignancy thereby by providing both molecular atari as well as a cellular target That we may be able to Use with either pharmacological paradigm or as we were just kind of alluding to using t. cells on to perhaps target. These abirin sells In in patients. I think this is a really big deal. And a pretty high profile paper as a result of some of these amazing findings. In as we've alluded to ankara. Cancer is just so devastating. It's got a very very high mortality rate and to me somebody who's not involved in the field actually quite surprising that we didn't know perhaps this particular mechanism until now maybe it's a combination of the new technologies that are emerging that. Allow us to kind of interrogate. These the cells of origins these cancers. But i guess the other thing is. I don't know much about patriotic cancer. And the mechanisms of how it arises is it. Brilliant quite homogeneous in that way in terms of narrowing down the particular sellable origin. Like do we know that. It's these asner cells that are doing the deed or can Pancreatic cancer perhaps be more heterogeneous. In that way. I'm asking you and do not necessarily an expert in this topic either. But what do you think i mean. I still think can't cancer itself in my opinion. There's no two types of cancer no to cancers that are identical right and although this is an amazing finding how applicable would be across the board. I don't know yeah that's a good point. I think that. I mean i wouldn't say that. It is a big high profile paper nature. And i think because they appended there that this is something that doesn't just happen in an experimental context. It's also noted in real life and he's neoplasms so yes. I think that it can cause cancer. Can we say that it it. It is the only way or is the way that the majority of pancreatic neoplasms arise. I i would say no. But i think maybe in support of that idea and i don't know why it's just my intuition but just the fact that it's been so so difficult To address this this disease. In the more tally so high. I don't know why but it makes me think that it's just this one mechanism that we we. We can't break through at least that's the hopeful part of me says that maybe it's just because we haven't gotten around to this We haven't observed that are found a means to to target yet. And maybe this'll be the breakthrough moment. Hey maybe five years from now. We'll have our pancreatic cancer survival on the order of leukemia Survival and you know eighty ninety percent we can keep our fingers crossed the elbe. I'm not holding my breath..
"trowbridge" Discussed on The Stem Cell Podcast
"As i said we. We haven't really moved the needle. In terms of origin. These pe- dax. We call him pancreatic duct adenocarcinoma. The derived from epithelial cells an execution pancreas right and within the excellent pancreases essentially to populations of cells that are lineage restricted. The astner cells and the duct cells. All right so when you look at The p dax the cancers. They looked up till right. And when you look at their origins they often come from these pre Invasive pancreatic neoplasms That also have a doctor identity but in spite of that There's been some genetic studies using mouse that suggests that the p dax and these pre peac neoplasms that they arise from the asner compartment right and also There's studies using mouse as well as human organize Showing that if you tweak them genetically to induce the cancer. Get these pre-cancerous mutations that you'll get From ductile organize that you can get A a p dak or precancerous neoplasm right. So there's a lot of evidence to suggest that There's a duct origin of these cells. And there's also competing evidence that say coming from the depart compartment all right now in parallel. It's also well known that what drives these tumors is telomerase right. Telomerase is important for self renewal. We all know about this In in the pancreas. Telomerase is really restricted to It's generally restricted to stem cells. But in the in the packers you see it up. Regulated usually coincides with pita. You know it's not usually up except when you see this transformation so this is a story from stephen are thandi who is at stanford and their goal was to really settle the the the question here. What are the origins. And what is the mechanism by which these pe- dex arrive. Arise and what they showed is by Manipulating turt- signaling They show that there's a very rare population of tur- positive. Ason or cells in the pancreas. They're dispersed throughout the excellent compartment. And these what they do. Normally in normal physiology is that they renew the pancreas by forming these kind of clone uil Expansion of ason herself. And if you mutate rask's In those cells you can get translated for inspiration to these pre malignant Our pre invasive neoplasms in the pancreas and this mechanistically involves rask signaling burke.
"trowbridge" Discussed on The Stem Cell Podcast
"Coronary plexus to inner myocardium It it in does not contribute to the vet venture glenda carter. I'm sorry does not contribute to the neo vascular at neonatal stages of those new coronary vessels. But in fact it's Sell it's the pre existing and the theme in coronary plexus of the myocardium. That does it. And what they showed in mechanistically is that it's mediated by a deal for notch one signaling And that's it. I mean it's a it's a pretty straightforward study nature biology. But i think it's it's it's it's addressing a really important gap in our knowledge As i said because the heart baskets are is critical also. I should note that they showed that the same mechanism Accounted for the regenerating neonatal heart so. The baskets are at following apex reception. Neonatal heart. they're able to get re growth of the heart has been it has been observed and it was mediated by the same mechanism. So it looks like we might be able to augment or modulate that signaling to perhaps seed neo angiogenesis In the context of injury or other pathological defects. So i think a nice story that answers an angel question with i think some degree of defending or in a definitive man. But i don't know what do you think you're you're you're the guy with all the knowledge on the heart. Tell me do you think they finally closed the gap here. Yeah i mean it's a great basic science study for sure I think this is a really hot topic. As you've discussed the idea of figuring out how the heart is able to vascular rise in Itself and ultimately hoping to harness some of those capacities for breathe vascular station in adult. This is a huge unmet. Medical need i think in this something. They alluded to in the study. There are a few different approaches in a few different hypotheses as to how this happened and one of the persons also friend of the show was done some work on this is of course kristie red horse. Who is the expert on all things Vascular ization especially early coronary artery development. I think You know there. There's still some work has to be done in terms of figuring out the exact detailed mechanisms of how this process of that actually happening a lot of work. You can ask christie about it. But the thing i've always loved about these studies and particularly this paper work. That's coming out of christie's lab is the exquisite imaging that you need to actually do some of these analyses lineage tracing enhance really deep convoked microscopy. It's actually figure out how these networks of vascular agriculture are contributing to the overall formation of the heart and the growth of the hearts. It's one of my favorite sub aspects of cardiac biology. Just because i'm a sucker for pretty images okay. Yeah allow pretty pictures in this one and you know i. It is worth mentioning that these mouse lines that they made were berry Precise In terms of not disrupting the endogenous. Gene expression also identifying genes And timing And all the cassettes Not to that..
"trowbridge" Discussed on The Stem Cell Podcast
"Yes the big problem but we got this new science And you know we're talking about this wave. But i'm gonna go back to old questions here also though in the hearts a nice segue This is about the vascular you know. I love Bestsellers in the blood and the vascular. The heart is arguably the most important basket you know. The hard is just a big muscle. It's going to spread all the blood. And it's the primary event you need to grow pass those microscopic stages right so arguably initial vascular station. The hearts the most important thing that happens in early embryo genesis And it's known that that initial vascular plexus is really important for the fetal heart to grow at all you know not just because of basler profusion. But also there's angie crying factors that affect the growth there But there is a question at in terms of when you when you switch from fetal to neo nate There's a another bowl burst vasko in the heart As the inner my cardio wall becomes thickened as the tobacco and compact compacts And it's not really understood. Exactly where the coronary vessels come from. In this process it's been proposed that The inner myocardial wall gets these new coronary vessels de novo from the end the cardio lining of the boeckler crips. But there hasn't really been the sufficient lineage tracy analysis of and the cardio cells particularly at these late fetal neonatal stages right. So you know we need to. We need to look if we're gonna we're gonna know And also not just where they come from but also the signaling mechanisms that drive that Vascular hearts really important. Why because we want to know how to reverse basler the heart in the adults Post infarct right And we know that the neo. Nate has the capacity for heart regeneration. That isn't recapitulated in the adult. The neo nate looks more like zebra fish So this is an open question. With a lot of clinic. Relevance and Bins vows grew bad Einstein albert einstein called her medicine. They've done a lot of work. Needed tracing the heart and the car corner vasko and here. They generated to new mouse lines. That were very high finesse. in high specificity insertion not disrupting the gene to maintain indigenous expression of this nature Prep tied receptor three. Npr three as well as dll for rate so the famous notchers notch lion And what they showed is that in that late fetal development.
"trowbridge" Discussed on The Stem Cell Podcast
"Episode two hundred two of these stem cell podcast regulations stem cells in the blood. Dr jennifer trowbridge everybody. We are dale on james shurmur. Welcome back to the stem cell. Podcast where we culture knowledge in stem cell research by talking to some of the.
"trowbridge" Discussed on Capes & Lunatics: Sidekicks
"As the co writer. The book was completely natural at speaking at that point heating and inserting up. Tim going to think polka team on is editor for a while. He found us. Paul ryan god bless him and then after that. Maybe joey cavalieri. I'm trying to remember. But that's you know we. We always had good luck with editors when they were never intrusive once. Yeah that's that's literally the run villes really natural like everybody was just a well oiled machine. I think that's why the run really stands out thank you. Oh yeah. Like paul ryan yeah. He's polish yes. Oh yeah you're talking about family and then After a while when you came back back. I think You introduce walis family. Where did that come from. That was well. I mean you know. The kid looks done stuff with his mom and dad And made them distinct and interesting characters and he doesn't stuff with chonkin and other sporting characters he had mine memory of this. And i could be wrong but my memory of this was that when he left the book and gave it to me he asked if he could take some of these characters like mason trowbridge and chunk over with him to wonder so that's why they his his supporting characters didn't show up very much in my first couple years just because they were bills characters and i thought he was going to do something with them and that was fine With mom and dad you know he's a small town kit and so it just the i wanted to get back to the family aspect. They also love the fact that walsh appearance aren't dead. I love the fact that he's not motivated motivated by orphaned revenge. Which is terrible terrible motivation to us. Because it's overused. So i mean that's that's where the family came from the big thing. I always say it's like even berry back in the day. His parents were alive. I mean it wasn't until recently where they had. Reverse flashback youkilis parents. I mean i kind of liked it just back in the day where he was like. We'll both of them. I got powers. You know it's the right thing to do to help people do for the sake of do. Can we bring that back. I know i know i. I'm of two months. I mean on the one hand. i'm with you. I still think that orphaned revenge. Even a that into flash is a longtime flash reader. Kinda makes me wince a little bit. I can't argue with the fact that it. They really seem to make it work for them. And and in a way that it doesn't feel completely gratuitous. I mean i think jeff really had a very strong idea what he wanted to do with. And i didn't like it at the time and i still have my reservations. But that's not a knock on jeff. It is the realization that time moves on and by now what seven of the audience of flash whether it's tv or comics now that's the berry they know and so i can't not that it's working for for them..
"trowbridge" Discussed on The Rich Roll Podcast
"Been a free diving competition going on. Yeah vertical blue which is couldn't get through this podcast without a free diving listen. Vertical blue is the tour de france. A free diving baby. It's it takes place in Long island bahamas at a place called dean's blue hole Which is just off. The beach stepped off the beach. There's a sinkhole limestone hole that goes down to two hundred and two meters so six hundred thirty six hundred sixty feet whatever that is and they drop a line william trowbridge one of the best in the history of the sport lives. There discovered the place as a free diving. Destination created the infrastructure for much in the same way that garrett did for naza ray will did for free diving. And what's beautiful about is no current conditions are always good. I mean sometimes visibility is better than others and it's always nicer to have some biz but really when they're going deep. It doesn't matter that much only matters for the pictures and this year is seeing some of the most incredible records that i. I can't remember seeing this many record. So i'm gonna have to put on my phone so i i. I don't miss anyone because it's a it's a big deal and everyone needs their needs the recognition. But let's start with alexi mulcher nov who we've talked about before who is the record holder for two of the three disciplines on the men's side the constant weight record which is a fin. Basically call it constant way because anytime you do competitive free diving whatever weight you swim down with you have to bring up with you so really all. The dives are constant way. It's just a bad name for it. Should be called the most no event where you're you're carrying some big wait and then when you get to the bottom you drop it and come back. That used to be the way so in the early days like in big blue. When we're that was the early days of free diving. They were competing in variable weight. Which is that you could take away deterring out or and swim back on you know. Now it's all swim-down swim up. And so he got. He broke his constant way record. Which one hundred thirty meters. You've got to one hundred and thirty one meters but more impressive than that. In certain ways was his free immersion dive. Which is you pull down along line. Free fall to the bottom. Get your tag and you pull align not wearing any friends at all. You pull line all the way back to the surface. That's how he did that. To one hundred twenty six meters and the was four minutes and forty five seconds and it looked like he'd walk around the block. I mean obviously. It was incredible but to be underwater and doing that kind of physical activity. That long it's just remarkable This guy minutes and forty five warm forty five seconds. This guy doing things that just haven't seen before he's broken the record on by fins Dynamic he's broken the record in ice and he's doing it all the only thing he doesn't have is the constant no fins record which is still wills. I think it's one hundred two meters and that's the on the men's side alenka art neck which we've also talked about her. She's a slovenian. And when i was covering the sport for one breath alexis record was still at one hundred. Twenty eight meters so it's still close. Lexi's mom natalia. Mulch inova the most decorated.
"trowbridge" Discussed on The Moth
"Thank you. That was jamey trowbridge. Jamie is a magazine publisher. Who lives in peterborough new hampshire. Although jamie says he is not cast off from the main coast in a decade he does set sail on a nearby lake every summer and on new hampshires frozen lakes and ice boat during the winter. Jamie says when you go out and a boat you almost always back with the story and if you're wondering what exactly an ice boat looks like head to the extras for this episode. While you're there you can also check out some photos of jamie and his family on their boat. The parody and a page from his father's logbook at the mosque dot org slash extras. This story reminds me of summer and the perfectly imperfect memories that i shared with my father. He was a complicated man and we often had a difficult relationship but he managed to make some the most magical time of the year. Our favorite activities were foraging in our northwest detroit neighborhood from mulberries and taking the prone branches from peach tree in our backyard and using them to fashion fantasy vehicles. Like starship cruises. It was an amazing time. And i cherish those memories with my dad. I'll be going back to detroit for the first time in four years this time. I'm taking my youngest daughter. At the top of our itinerary. Is visiting our old neighborhood to see if those mulberry trees are still standing. I can't wait till indulge in mulberry soaked fingers with my daughter the same way that my father did with me. That's offer this week until next time from all of us here at the mosque have a story where.
"trowbridge" Discussed on The Moth
"Sales to help the boat perform better in under certain conditions. We didn't just have one job. We had four jobs and we had the drifter and the flasher. And so i would go up to change those sales while. We're gonna need to take down one ship. Put up another votes going up and down. You know what i can do to just hang on but after a while started getting my hang of it and in the end how fast they could change it. Sale became a point of pry now as we got better at sailing. My father just kept upping. The ante didn't matter that he didn't know what he was doing he was just going to go for it. The dicey est thing we did with sale in the fog we used to go out in the fog with just a chart and a compass to navigate no. Gps no radar. Now here's what you need to know about doing that. You don't know where you really are in the fog with just a chart and a compass just know where you think. You're supposed to be so. I go up on the bow of the boat in the fog and had looked for anything we might hit and some kind of mark in the water. That's going to tell us where we actually are. One time up there. And i see this. Green channel marker coming out of the fog. it's green. Can i call back to my dad. I see green. Ken number six and i look back at them. You know barely see him back there. The fox thicky consulting the charney calls up kathy. Green can number six miles from here.
"trowbridge" Discussed on The Moth
"Much so that we had to clip my little brother onto a lifeline case. He went overboard one time. We woke up in the middle of the night and we were drifting out to sea anchor just dragging across the ocean floor. Father you get so mad when things went wrong motoring dying. I just had that thing fixed. And then he blamed for breaking those early sales. My heart was just in my throat. What was going to go wrong next. But i never considered quitting the crew with the parody. It was a chance to be with my father. Twenty four seven sometimes for as long as a week and it was so different from at home at home. He was the superhuman and he was busy. Never around on the boat got to see a different side of him. He wore these schlumpy close. And you didn't care pop tarts for dinner. It was it was just amazing to be there with them and in the evenings we would all sit in the and laugh and tell stories and he would sing as we sat there under the stars. The the other reason. I didn't quit being the perez was i started to prove myself as a sailor we used to race didn't know we were racing them but we were racing them and he.
"trowbridge" Discussed on The Moth
"To the moth podcast. I'm your host for this week. Angelica lindsey ali this episode. We have a story from the moth main stage. Jamie trowbridge told us in portsmouth new hampshire where the theme of the night was the ties that bind. Here's jamie live at the moth. When i was twelve. My father bought a thirty six foot sailboat. Called the parody. It was really exciting. When i learned we were going to blow all go sailing but i was a little surprised because as far as i know. My father's never sailed not even a small boat. It all started right here. In portsmouth we got on board. We started to motor away from the dock. The motor died we had to be towed back in auspicious beginning. But i knew that sailing when my dad is going to be great because he was so good at everything he did even at twelve years old. I knew it was an accomplished man. He was a graduate of princeton. It was the president of our family business. And he'd recently been elected to the new hampshire state. senate. I was the only kid in my school with a trowbridge estate senate bumper sticker on his lunchbox. Naturally i wanted to be just like him but so far it wasn't working out so great. He was a three sport varsity athlete. And i can't catch all he's beautiful. Tanner and i appear to be tone deaf. I sense his disappointment in me. His oldest son so if this sailing thing is something that we can do together i am all for it so now. It's our first time actually sailing and we're up in scott bay means rocky coast the whole family's on board and i'm feeling a little tense because we narrowly missed hitting a few boats getting out of the harbor and now we're sailing down the coast. We're going to sail. Between these two islands. The boats healing. That feels a little weird. I looked down in the water. And there's grass in the water now. I know now that grass in the water is not a good thing. Grass in the water means shallow water and maine's knob. Scott bait is full of ledges hiding right beneath the water so we sail right into allege is a huge crash the wave picks back up off the ledge crashing back down the whole boat shakes. Were going up and down on the ledge and my mom is running around putting life jackets on. She's preparing to abandon ship. My dad's yelling. Everything's okay over things. Okay over and over in a way. That.
"trowbridge" Discussed on The Moth
"Over the years moths stories have inspired many reactions. Laughter tears in two instances wedding proposals but almost stories inspire curiosity audiences tune into the moth and come to our live events because they're curious about others and want to hear their true stories to celebrate the way stories can spark your curiosity and take you beyond the expected. We're collaborating with our friends. At sierra nevada brewing company to bring you stories of inspiration passion and the spark that set someone on a brand new path the moth and sierra nevada. Invite you to stay tuned after today's episode for a bonus story told by sean lasley about her father's unsolicited words of encouragement. Pushing her to be better. It certainly sparked our curiosity. We wonder will. Its bark yours audio books on apple books gives you the freedom to listen to that one story. You really want subscription free whether it's a sci-fi novel or a mystery when that moves you or one that soothes you. You can find the audio book that surely inspires you on apple books any genre anytime at your own pace explore the new collection of nine ninety nine audio books on apple books and listen now on the apple books app. Welcome.
"trowbridge" Discussed on SPORTS GOOFS
"Let's let's let's actually get a sports related non sponsor. Your mom knows we'll talk about it. So yeah the nike city a collection or city connect with seattle city edition same. Nba did So now baseball's doing it so the cubs came out with the wrigley ville uniforms today. They're tight ends. Essentially that's basically yeah. It's one hundred. I don't hate it but it's so it's so it's so it's a shock value to me because i don't think cups like that. I mean i do. i think it's better than chicago. South side one kind really. I think south side one. Because the first one i saw was it with any of its players. The tone of the recession over that was the that was the edit. That was like somebody editing. It a very bad photoshop job of it but now they have actual photos of tony larussa with the sideways cap. That's the whole thing. First impression matters. Yeah and that's what my for special South side and it was towing the risk because he really either reminds me of how you do. Fellow kids four. It reminds me of just one of the zuckerman. Berg is a spoof. Charities like a gun in the scary movies. I came to the scary movie. Two so it's three on. It was so bad. But i hate it. I think it's just not the collar coordination that i would imagine. I don't know why they come. Put wrigley field and use their typical blue that they had there. Oh yeah yeah. They're all better than red sox ones. That's for sure. The red sox ones are the worst one so far that it was like the yellow blue boston marathon. Once and i get it i understand. I like the nice that the you know the honoring the things. But it's also. I mean it strays away so far from red sox that it's like i don't know it just it doesn't really work aside from just as a one off saying hey uncreative dirt doesn't it doesn't stay away from the red sox trowbridge But yeah. I mean i'm more fan of the white sox. One in the cubs. Want to be honest. I think because one's just kinda like okay. They did a thing. Grandpa tony from the picture. That i would probably like it. Yeah yeah the south side stuff. Looks pretty cool. I mean from what i've heard. It's it's flying off the shelves so of course the marlins one is Flew off the shelves here. Which is you know not many marlins things fly off the shelves but that one did they definitely hit on that one and so let's see so we got to teams the boston. Red sox the us delaware north of cups and I think was the diamondbacks. The giants and the dodgers are the ones that are left to reveal their stuff. I'm kinda weary about what the dodgers going to do the giants. I'm not sure either. And i have no. I mean i guess the diamondbacks might do something for partly native base. Me and my click the arizona coyotes or something with their their retro uniforms. I have a feeling it be something like that..
"trowbridge" Discussed on Heartland Newsfeed Radio Network
"After thing is over and everything's explained seems quite simple. All little jigsaw pieces fit together to make the fiction but with poor handling trowbridge dead. Four thousand dollars gone in the bank about the takeover his ranch. Jackie and i with the colonel and his daughter faced what seemed to be an insuperable problem. There appeared to be no answer whatsoever to supply a reason why some unnamed packing house should want both ranches so badly they pay a fantastic price visit to the cattle broke a big john. Having been interrupted by the finding at trowbridge is buddy. I asked the kennels form and route to ride into town. See if big. John wouldn't come out to call on us and he did in. The conversation was most enlightening. You can talk all you want. But good but i'm not changing my mind not hall but surely colonel. I must be some price. We could agree. Ought to take the early on. I don't mean to but in big but just how high can you go. Where i don't know for sure but i might be able to reduce my clients to raise their another few thousand dollars and maybe another few thousand dollars on top of that Yes it's possible. It's possible in other words. Your so-called clients want this property any so called clients. I just wanna you hinting at figure. Here it is. No people in their right minds are offering a ridiculously high price for a couple of ranches like these. Do justice supposedly raise cattle for a and now in other words or just calling me a liar. I don't need you to put words in my mouth but since the shoe seems to philis let it go at that hangs cherokee when i saw him go for his gun. He wants to clear leather. It's all right with me. Big john figu big enough to try it. Give you a chance of that right now but just having to be convenient main your insurance policies and paid up kind of that offer. I made good for six hours. You change your mind if you got her mind. You know where you can find me. And my i'll be darned you say nine handbag down. She'll my heart good chance to see him get his come up and that still doesn't explain. Just why anybody wants to pay the price offered you for the rank it convinced me of one thing cherokee. They don't want this place just to raise cattle. Tell me something colonel. Are there any minds or or deposits anyplace around here. She you think they found gold up on the ridge at the back into place. We haven't the slightest idea. All i was doing was asking. You just gave me an idea. And i don't think that's what chicken up. Why are you going to you. Stay here and keep visits company remington. These.
"trowbridge" Discussed on News 96.5 WDBO
"Now six twenty for your listing Orlando's morning news summary computer Marcia Taylor well it was a clean vote in the Senate ninety six zip I believe April is going to be tough for the March and I think at this point may could be even tougher than April and people need to be ready for that now it's up to the house will take up the bill tomorrow it's our top story coming up in the news at six thirty some chilling stats on the virus beans death count surpasses thirty six hundred with an overnight tally of seven hundred thirty eight deaths the highest death toll in the world behind Italy South Korea is demanding international arrivals download the phone app to track potential symptoms of the virus or they will not be granted entry into the country in Italy police are making spot checks of people who are out and about to make sure that they are out with reason people who can only exercise a certain distance from their home and if France joggers can only run within a half mile of their home for no more than an hour and no more than once a day Germany people can leave their homes as long as they're with members of their own household and totally toilet paper jokes are common it's impossible to find North Korea Carolina the eight state to be declared a major disaster due to the virus president trump approved just hours after Texas and our state Florida the actual free up federal funding to state and city governments president trump hearing the postponement of the twenty twenty Olympics it's going to be a fantastic Olympics twenty twenty one I think it's going to be a fantastic Olympics it was the absolute right decision to delay it for a full year and now have a full beautiful Olympics opening ceremony for the games was scheduled for July good morning it is now six twenty six your listing Orlando's morning news updated weather in traffic every six minutes good morning Joe that he builds today right through the weekend this weekend at middle nineties with record highs likely for today were in the upper eighties mostly sunny with a chance of a passing shower tonight we'll have some patchy fog were down in the sixties it'll still be mild for tonight then tomorrow mostly sunny hotter highs around ninety one from channel nine Eyewitness News I'm meteorologist Brian shields right now it is up partly cloudy it's kind of nice this morning though seventy at Orlando's severe weather stations take touch Cutie triple team traffic let's go to a helicopter in there wanted terror frown for less bounce off major problem maybe a break later to ensure a approach slowpoke in front of you but take it easy everybody's trying to get to the same place out here up to speed on Eric brown in there one is Trowbridge board is brought.
"Published in time magazine can you guess what the most stolen food in the world is oh weird says it's rice cakes just kidding it's cheese according to a study four percent of the cheese produced in the world is stolen the lot of contraband chatter and bootleg breed but supermarkets view it as a high risk products now guess it's just too good to pass up oh come on