19 Burst results for "The New England Journal Of Medicine"
Liberty Station
"the new england journal medicine" Discussed on Liberty Station
"Addition to other drugs or even down the NG tube when someone's on the ventilator reduced mortality. Every single American hospitalized should have received Ivermectin. Plus other drugs. 100% of them. 100%. It's safer than Tylenol. Now the FDA is being sued over this because the FDA put out false statements at its only horse paste and they had a campaign against Ivermectin. In November of 2020, the World Health Organization said Remdesivir under no circumstances should be used to treat COVID-19 because it doesn't improve mortality and it causes kidney damage and liver damage. The World Health Organization said that they were backed up by an ethical review and the European side of critical care. So when the World Health Organization said that, the California HHS should have called an emergency meeting and gotten all the Remdesivir off the shelves of every California hospital. And when I testified in the Texas Senate, I said the same thing in Texas Senate. I said that happened under your watch. You're falling asleep on the job. You falling asleep on the job and impatience and families had to defend themselves against Remdesivir. And patients and their families had to try to sneak in Ivermectin. And these grows breaches in the standard of care, the public should be outraged and they should make each and every doctor and hospital pay for this. Now, vaccinated or not, we need early treatment, the new risk paradigm, which I've recently published on our substack, is really important. The most important feature for risk now is if you've already had COVID, when you've already had COVID, the chances of any serious outcomes with the second infection are negligible. How many people out here have already had it? Just about everybody. You're good, a recent study by chin and colleagues published in New England Journal medicine in October of 2022. Show, 59,000
The Doctor's Farmacy with Mark Hyman, M.D.
"the new england journal medicine" Discussed on The Doctor's Farmacy with Mark Hyman, M.D.
"That really takes away one of the sort of drivers or triggers or things that's really exacerbating their sort of phenotype or their symptoms. So if you are able to get the patient to sort of embrace that approach, I do think that you will see that often patients will see benefits. I think it's something that has to be monitored. I don't think all patients will suddenly start having regular cycles and their hair growth isn't going to suddenly go away. But some patients may have more cycles, some patients may be able to conceive that way on their own. Without fertility treatment, but others will not. So I think it's something that I try to discuss as an option, but I think I shy away from saying like, here's a way to fix this because I think in all honesty it doesn't fix it for some patients and that's really frustrating if they feel like they're sort of somehow failing. What sort of speaks to how little we know, right? Because in some patients it works and some patients, it doesn't, you don't know which one's which, right? And it's really about personalizing care. Yeah. So I think it's a challenge, and I do think it's PCOS is definitely a disorder that just takes a lot of personalization because it's such a diverse heterogeneous disorder. The concerns and the goals are often very diverse. So I think no patient and no treatment plan quite honestly is exactly the same. And you know, years ago, I read an article in the New England Journal medicine about dec inositol and PCOS, which is a derivative of B vitamin. It seemed very promising. The kind of seem to fall off the radar. What is the role of that and or other supplements in the treatment of PCOS? I mean, I think it's still on the radar in the sense that people are using it. People are trying to study it. I think that there's been sort of mixed results in the studies that are out there. I think we're somewhat hampered by the fact that people are taking it in different sort of formulations and different ratios and different doses, dosages, which makes it a little hard to sort of figure out whether it's working. I will say anecdotally, I do have patients who seem to become more regular in their cycling when they're taking it.
The Doctor's Farmacy with Mark Hyman, M.D.
"the new england journal medicine" Discussed on The Doctor's Farmacy with Mark Hyman, M.D.
"How your body can heal itself. He is best known for leading the angiogenesis foundation and his groundbreaking work is impacted more than 70 diseases, including cancer diabetes, blindness, heart disease, and obesity as TED Talk can we eat to start cancer has been seen over 11 million times. He's coming on the Doctor Oz show, Martha Stewart, CNN, NPR, Voice of America. He's been at the Vatican's unite to cure conference where he invited me. I spoke virtually during COVID. I wish I had got to go. Maybe next time. He's the author of over a hundred and scientific pumpkin publications, including ones in major journals like science, New England Journal medicine, lancet, and he's on the faculty of tufts Harvard and Dartmouth, no slouch. Welcome William. Thank you, Mark. It's always a pleasure to be back and have a conversation about things that we both care about. Absolutely. So, you know, I think the real challenge is that people don't really get what food is. Most people understand they need to eat to live, and they need to actually have the ability to choose foods that are nourishing and not too many calories. But people don't understand the power locked in the kingdom of plants and even animals that are medicinal. True drugs in the sense of pharmacologic activity. And as I began to think about the science, years ago, when I was when I was studying functional medicine, learning about food is medicine. I'm like, what does that mean? And I began to look at the biochemistry and biology and the pathways and how these plant compounds somehow know to bind to specific receptors in our body. It doesn't even make sense. It makes sense that you have testosterone mining Twitter.
The Tim Ferriss Show
"the new england journal medicine" Discussed on The Tim Ferriss Show
"Fat stores. I mean, cognitively, everything changes. It's very, very interesting. It's hard to go back to how it was before in terms of viewing food and so on. Yeah. It's totally different. Looking back over your stunts, all the magic, the endurance feats, which ended up being more dangerous than you expected or scarier than expected. Probably the 44 days with the water fast in London in a box because I think I went into mild organ failure and I dropped a 33% BMI, which was well documented, but it was the recovery on that. I think to this day, it's still screwed up my metabolism and my weight goes up and down really fast and it did real damage. Vitamin deficiencies of pigment. I would find who has been there 44 days. Food only water. I lost 60 pounds and 44 days. The plexiglass diet. Not recommended. Not recommended. Dietician will not have this on the multiple choice options. What did your refeeding look like after that? Well, that was a really interesting part. So after I did the 44 days, I was brushed to the hospital where I stayed for, I think, two weeks. When they started refeeding me, I think my phosphate levels jumped out of control and I almost went to shock and died, and that was the refeeding syndrome. We published a paper and then New England Journal medicine about the refeeding syndrome, which is because most hunger strikers in the past they do it in their very anti government anti, you know it's the first statement, or as I just did it as a performance piece. And therefore I was willing to give all my blood and all my urine to doctors and let them use it as research. So it actually became useful in the sense that there was a real documented study of the prolonged effects of fasting. 44 days or a starvation technically, yeah. Were there any of your performances on the flip side that you thought were going to be very difficult or very scary that were easier than expected for you for whatever reason? Nope. What is magic mean to you? Because you do so much more than illusion and magic. I mean, you really have sort of a full stack performer kit at your disposal. But what does magic mean to you? For me, it's just a beautiful performance art. It's something where and it's also like you learn a really difficult skill. It defies logic. And then you have an immediate reaction to it. So it's something you can do almost anywhere anytime. And it's also a constant pursuit of information, but information that isn't readily available. So it's like you have to dig up history, you read about a guy that had done something from a hundred years ago. He died took a secrets to the grapes. He spent years trying to understand how he did it and it's trial and error practice, repetition and then finally all of a sudden you're able to do these things that you had only read about. One was called the human aquarium, which is about a guy that could convert his body into an aquarium where he could store creatures. Another was I'm not kidding. Yeah. Another was a magician. Another was a sturgeon in his mouth and regurgitated. Well, anything. Anything that could live in water and land. But then you also find there's another guy that was the human dragon. And he could drink kerosene. It would float on top of gallon of water in a stomach, and then he would blow fireballs out of his mouth, igniting a huge fire, and then just when he thought that was the end, he'd use a gallon of water that was stored in his stomach and put out the fire. But of course, of course, one time he did it wrong and died. So and.
One Life Radio Podcast
"the new england journal medicine" Discussed on One Life Radio Podcast
"But you know so. Let's go back to vitamin c. Concerning what hospitals are doing our most hospitals using vitamin c. To treat these diseases today or is there still a resistance enormous resistance. I must say though. One unintended and beneficial consequence of this pandemic was. It is focused a spotlight spotlight on vitamin c. As is never occurred before and sort of like The expression goes to cat got out of the bag and a lot of vitamin c. Started being used early on the pandemic and in my judgment quickly. Got out there before the fda could start issuing mandates as to don't use vitamin c. for this or don't use vitamin c. For that and too many people are already getting dramatic results very early on the pandemic and entire network of hospitals. Some twenty plus hospitals in new york began using vitamin c with excellent results. Still not as good as they could have because even the hospitals that are using the vitamin c. And the positions that are out there that are fighting the establishment of using vitamins. D still aren't using high enough doses. That's another story. It's also very interesting to note that. Virtually all of the significant investigations on high dose vitamin c. and treating clinical disorders comes from china. About the same time that the Will hand area started getting heavily infected with colbert or whatever this infectious pathogen is or whatever this agent is one of the areas in china shipped manufacturing vitamin c. Shift fifty tons of vitamin c powder to wuhan kinda tells you that the chinese new right up what the best thing was to deal with that if you ship fifty tons of vitamin c powdered any city in the united states would have sat on the warehouse until the turn brown. I believe that. I read in the epoch times that they didn't article that covered it back. I don't know probably six months ago. It's a weekly newspaper that i get. I don't know if you're familiar with that but Yeah they they featured an article that said that that's what Went china was using to fight. Fed was vitamin c and vitamin of course but yeah and very effectively. Yeah well so. So what type of vitamin c. Cause i do the liposuction. We'll packets and i am also have bought. Dr mccullough's liposuction vitamin c. By the way he was on the show yesterday and he said he's a good friend of yours. so how. how awesome is that back to back that you guys sir. Yeah and so are you. Is i greatly respect his courage because he's out poking the bear in the eye and that was that's what needs to be done and he needs somebody brave to do it. So hats off to dr where cola and is long-term fight for medical freedom and doing things correctly as well as he's fighting against the political consequences which is unfortunately inextricably interwoven with everything that we're doing here. I mean you have on. We talked earlier. And i mean healthcare. Make no doubt about. It is a business and foremost absolutely. I mean just anybody i mean. Nobody likes to take that. Their doctors doing anything less than what's in their best interest. Well i'm sorry that's the exception and not the rule okay. I don't know why this shocked so many people of the pharmaceutical companies placed enormous pressure on doctors and doctors. Don't like to be hassled. So they just promote the pharmaceutical drugs. Make a lot of money. Say well this is what Our new england journal medicine said to do which is also supported by the pharmaceuticals but unfortunately the docs take it too far. And i can't tell you the number of emails. I've had over the years with desperate individuals begging begging their doctors in the intensive care unit to give their loved ones..
Boston Public Radio Podcast
"the new england journal medicine" Discussed on Boston Public Radio Podcast
"And and i think you know. We need to in america and many places. Look at the data and say okay. There's no evidence at a harmless. But how much evidence is there that it helps us. And what's the bigger picture. The fact is despite the fact that the us has done a tremendous job actually sending out vaccines to other countries Last week at a much higher percentage of vaccinated and other countries the likelihood of variants like delta. Coming down the pike and causing even more disruption goes up and so. Why don't we just pause on on taking up that next dose until we actually know what it's good for and frost that that that the vaccines that we have in our bodies right now are going to protect us from getting very sick and hospitalizations. As as we've talked about on prior shows. I thought it helped in terms of increasing your ability to fight off infections. My wrong i thought that was the reason for the futures absolutely marjorie. Yeah absolutely did they. Data has shown Again when you look at Data that's coming. Out of for instance. New england journal medicine that was released in israel and some other countries it shows that yes when you get a boost or your antibodies go up. The question is is the. Antibodies going up significant and not. How much do you will be protected from severe illness in hospitalizations and are the antibodies. That are going up the right. Antibodies are they the ones that are actually gonna most significantly protect us against the virus so again the data that was reviewed by the fda. I was actually really pleased that they came out with up to moderate response. Saying let's hold the horses a little bit. Likelihood is that will recommend it for people sixty and older people who are more likely to need me need a little bit of a immune boost. But let's just trust that the vaccines are working well enough for the rest of us and that we need to really now continue to push on getting the vaccines distributed to people who haven't gotten any doses. Let's go to ryan in the car. Thank you very much for calling ryan. Heireann thinks so much question for the doctor..
FoundMyFitness
"the new england journal medicine" Discussed on FoundMyFitness
"Preterm birth small-sized for station. Age congenital abnormalities. And even neonatal death and they compared the rates of people who have gotten the vaccine were pregnant to the registry so the v. save pregnancy registry data and compared it to the published incidents of these occurrences and what they found every one of these cases. Is that there was no statistically significant difference in terms of what they saw in the pregnancy data versus what they should see in the regular population. finally what i would say from my standpoint is to direct you to dr vicky male who we've had here on may cram. It has a twitter account. She is a reproductive immunologist. That has founded heard tutti to always constantly being updated in terms of data in terms of not just pregnancy but also breastfeeding in terms of getting pregnant in terms of all of those risk factors. Highly recommend that you check her out on twitter. But be interesting to hear what dr patrick has to say. I'm just sort of adding onto the new england journal of medicine paper that you just referred to there was a follow up study. It's still reprint to my knowledge and this study was done in around twenty five hundred people and they were women specifically they were given the They were given a kobe. Nineteen vaccine before twenty weeks of pregnancy and much like you mentioned with the with the study in new england journal medicine. The miscarriage rate was on the low within the normal range and it was action on the low end so it was about twelve point. Eight percent of miscarriages that occurred and the normal range between twelve point five percent to eighteen point seven percent so again it was on the low end of the normal range. There was another study that was published last june and it was in the american society for reproductive medicine and that study found that neither having previously had of truth to infection or having had a kobe nineteen vaccine affected embryo implantation so there was no effect on the ability of the embryo to implant into the uterus on top of that there was a very small. Study looking at fertility in men and this study found that there was no effect kobe. Nineteen vaccines on any of the normal sperm parameters that are measured like mobility etc. Like there was no effect on that. So i think generally speaking it seems as all the all the data so far points to no effect of kobe. Nineteen vaccines on not real large effective kobe. Nineteen vaccine on fertility. Okay dr patrick is next questions for you. This is in your wheelhouse. And it's about the amarna vaccine specifically and since this is for a lot of people new technology technology they haven't heard about and there are rumors that this is somehow gene therapy and it's going to be impacting our own dna within our cells. Can you speak to that. And what are your thoughts about those rumors. Sure i think it's understandable for for most people to to be a little concerned because they've never heard of this marnie technology the word arnaiz in it and you know it. It's it's a little overwhelming innocence. And i think as i mentioned earlier when i was talking about from thousand foot high mile high. You know viewpoint how these vaccines work..
FoundMyFitness
"the new england journal medicine" Discussed on FoundMyFitness
"The has declared that hospitals now because they're overwhelmed are going to start to deliver basically rationed care. You should not expect the same standards of care that you're used to expecting the healthcare delivery system because they're just not able to give me give some specific examples instead of having one intensive care nurse for two patients. It's now going to be one intensive care nurse for six patients with some help from non. Icu nurses because they're overwhelmed. You cannot transfer patients to higher level of care for things that they need to get done if they have very advanced cancers for instance because those hospitals don't have room if you need elective surgery their elective surgeries are being canceled. Traumas are still happening. Babies are still being born. These are the problems that we're having in a situation where you may think that because you're healthy and strong young you're not going to be affected but if you were to get into a car accident or you know somebody wants to deliver a baby and has a complication. It's going to be difficult for those things to happen. And so this is the thing that's occurring and going back to my experience in the last couple of weeks every single one of those patients in the hospital that were there in their thirties they're forties were not vaccinated and it's based on information. That's coming out that you're making decisions based on whether or not you should get the vaccine because you hear about side effects or you hear about things for instance about myocarditis. Well here's an article from the new england journal medicine. Peer reviewed published september. Sixteen two thousand and one looking at the israeli data with almost a million subjects in each arm. So what we have here plotted.
The Last American Vagabond
"the new england journal medicine" Discussed on The Last American Vagabond
"Here's what it says in regard to myocarditis which i think is very very relevant and i found a couple of points in here that i that i didn't really relax. Time sar celia to infection. Oh excuse me. For those in the podcast. This one is from the new england journal of medicine. The land was referencing is just one. I've already showed you in the past. Which the exact thing finds it. There is an increased risk of myocarditis. It says sarah. Stevie to infection was not estimated to have a meaningful effect on the incidence of lymph limping pathway herpes infection or appendicitis but it was estimated to result in a substantial excess. Risk of myocarditis. Let me read that again. It was estimated to result in a substantial excess risk of myocarditis star cb to infection also estimated to substantially increase the risk of several adverse events for which vaccination was not found to increase the risk. Your understand what that just said. Not only is it telling you a substantial risk of myocarditis increase but then it goes on to say that infection after that. So you get the injection you get myocarditis or whatever else then you get infected. Because we clearly see that happening and that substantially increases the risk of adverse events. You know what that's called antibody dependent enhancement or bleecker mimicry or pathogenic. Priming watching these things happen. They write their new england journal medicine now. That could be one explanation. The bottom line is the injection being taken and then getting infected caused those weird junction infected. It then causes more severe risk. We saw the studies. The back this up at two point four increase in severity of adverse events. We keep seeing this stuff and they just keep ignoring it. This is why it's so infuriating. People that pretend fake news because they look at a fact check as. We're walking you through. The reviewed science from the new england journal medicine from the british medical journal from nature from the lancet. It's infuriating but what we do. We're here to do it for you. And says including an estimated excess risk of arrhythmia. Too by the way arrhythmia right. Same wheelhouse here talking about this all. These things are leading the things that we're talking about the thrombosis strokes that all of the it vaccine induced thrombosis stumbles thrombosis thrombosis pena..
The Charles Moscowitz Podcast
"the new england journal medicine" Discussed on The Charles Moscowitz Podcast
"You catch cove in nineteen from other people and i'm basically hardly around other people and i messed up in. Very careful about social distancing. Wash my hands. And all the various things i mentioned last week i think god forbid a societies really just collapsing. There's a whole bunch of things going wrong and we have incompetent leadership and so they just go after the wrong things like the the people in leadership aren't getting the results. People are seeing that society's collapsing and so the leaders you have to make it look like they're doing something so they chase general red herrings or you're just pointless issues to try to bolster up their authority catalytic cracking down on you. You know god forbid You know the the leadership is in accomplishing anything. And so they're going to crack down on you because you're criticizing them and and to me that's just human nature the nature of power. So it's not. It's not surprising Like i'm not a doctor like medical vice. I have done quite a bit of research to the virus itself but You in terms of medical advice how to deal fit about whether those treatments work. Joe rogan's obviously a exceptional athlete. And you'll fear factor fame. He probably has exceptional immune system so could be that he would have a virus of any way office in the heat. Took the prescription. And also i have a on a Comment he didn't trump also legalize the right to try to remember that i mean. That was one of his initiatives as executive order that doctors have the right to use its mental drugs. They don't have to go through the arduous process and by the way the drugs are we're talking about the drug in the drug those of both. Fda approved drugs. In the case of the drug it was approved in the nineteen seventies. it has been used by millions of people all over the world quite safely. No drug is perfect. Of course if you leave read the fine print of just about anything that you take you see that there are there are there are side effects but nevertheless it is fairly conventional in terms of. It's up it's dangerous and it has been used for various ailments all over the world but yet you cannot talk about it yet. In last year you had the lancet which is one of the world's most premier medical journals and the journal and the new england journal medicine also very prestigious journal. Run the study which denounced the age drug and made claims that it was dangerous and ineffective and then they had to retract that study which was unprecedented. Never had they had that happen always a very well respected and known to do very serious vetting that would they would have to actually retract. A an entire study is actually a scandal for them and should be and it was even though it was wasn't nagged me. Neither one of us are health expert. Doesn't pay to get too much into the nature of the beast is You're just as more and more things go wrong. The people in power You democrats specifically need to explain why things aren't going the way they want him to end therefore they're gonna say 'cause we don't have enough power in they're going to try to gain more power and you'll krona viruses going back up and you're so you know blame it on the on vaccinated blame it on misinformation blame it on all these other things and saying it in order to defeat krona virus. What we need to do is you'll give more power to them. And you'll god forbid you have the situation where there's a distrust of the citizenry of by the government and people are starting to turn on each other in in. Maybe if the texas abortion ban..
Tom Roten Morning Show
"the new england journal medicine" Discussed on Tom Roten Morning Show
"And then they rolled straight into the Emergency use authorization where we all got the jabs but even the fda now in the licensure packet for bio intech. There's a clause in there where they specifically admit that the databases that they had hoped would be able to detect. These kinds of adverse events have turned out to be inadequate so that's the fair system v safe etc. The fda now admits they were inadequate. Then as if that wasn't good enough the fda played another little trick with this licensor normally. There's there's a group called the ver- back. It's an acronym the vaccine related but biologics advisory committee and Any time the. Fda comes up to a decision about whether or not to license vaccine. This independent scientific group has to review the same data that the fda insiders have reviewed. And there's also supposed to be a period for public comment associated with those ver- back meetings but the fda decided that there was no controversy here and absolutely no reason to convene the normal br back meeting which by the way the ver- back is still meeting. But they're talking about lou vaccines and some minor issues so they. They're they already got their scheduled meeting. They're just not going to talk about these vaccines. So the fda Totally bypass their normal process for external review In the case of these because they said there were no controversies and so there was no reason to have that review. I think tat is an amazing statement. just just to assert that there was nothing controversial here now. Another thing that's fascinating was that they issued this authorization to bio intech the day before. Two major papers dropped. That showed that the adverse events in the new england journal medicine the adverse events were much broader than they admit to in the licensing package and The other paper is the one that shows the natural. Immunity is Broader and Last longer than the immunity caused by the vaccine there. Some another paper also from israel that showed that the effectiveness of the vaccine to protect against infection disease by delta was lower than than with the previous strains in the other thing. That's fascinating about the fda package is that they completely disregarded all the delta data it's all based on the alpha and beta data which is now obsolete so you got a license for a vaccine that doesn't exist yet on the shelves here in the states based on data for viruses that don't exist anymore in the states that makes sense. It's it's unbelievable it really is. This has all been very eye opening for all of us. Dr malone and is i thank you for the work. You're doing to get the truth out across america. Thank you for taking time this morning. To come on this program and I just hope that That you'll be able to continue to get the truth out. We've been talking to dr robert. Malone the inventor of the m are in a technology dr milan be safe and thank you again for coming on. Thank you and enjoy life and paradise right..
Noble Warrior with CK Lin
"the new england journal medicine" Discussed on Noble Warrior with CK Lin
"The nuggets at that sweet spot of stretching the imagination stretching the believability. But it's still not so far out there be dismissed right away at boy. You just keep these questions coming. Ck so Number one is that we site are stored our source correct. It's like because people make these claims and you say it sounds too good to be true than we doubt it. We question it. We just lost trust so we always start. Did you see the two thousand twenty one april issue of harvard business review. Did you see that. New england journal medicine said this. Did you see on the on. So we cite our source and the second thing you can. You came up with a sweet spot of a statistic. It can't be old news because that's an eye roller bow by your wasted my time and so honey come up with him. Recency equals relevancy so when we are looking for these statistics he studies these research. Your something that just happened. Two months ago ads. Relevancy and recency an urgency to our pitch. So do we say. Did you see the study just two months ago. You see already the browser up. Because oh it's so it's more relevant. John kotter out of harvard said. Do you know the number one prerequisite for change. Glad a sense of urgency. So you just asked to key question because if we're coming up with statistics once again that show it's getting worse than it's costing more than it doesn't need to be killing this many people that people don't need to be suffering here and it's recent you are packing in urgency relevancy and immediacy in a way that people are more compelled to act So do you as an expert again because you breathe tons of news and research. Data's reports how do you pick up the juiciest thing of the filter down to the thing that the staff is gonna be right hook and i recommend free stats and we want scope. Because we just don't want money money money because maybe our decision makers maybe that's their top priority..
The Current
"the new england journal medicine" Discussed on The Current
"This book is called relaxed dammit. Tell me knowing what you know. We spoke in a number of times As as i've said earlier you were debunking. Sort of scientific quackery. What was the impetus in writing this book now well studied misinformation and how pop culture represents science for for really decades. And i got the sense that you know. We always talk about the big things. Matt you know things like You know vaccination hasn't seen incredibly important Climate change at gmo but these same forces impact our decisions that we make day to day so You know the as you point out the gimme because it takes place over a day. And i really look at all those all those decisions and it's kind of an excuse to to look at those social forces you know Fearmongering misrepresentation Through a new lens and and get a sense of look this impacts all of us and you know is a few tools we can. We can cut through the noise. You say that. We live in a knowledge era paradox. What does that mean. Well we've never had so much sciences. We have right now. We've never had so much access to science as we have right now. You know you could go on on google right now. I think he can do it right now. And and you could find studies from the new england. Journal medicine the Jama incredibly easily right. And even when i started my graduate work..
FoundMyFitness
"the new england journal medicine" Discussed on FoundMyFitness
"One was jim. Johnson worked with asthma patients in lee in two thousand seven we published with small study where we found that these were overweight. Asthma patients and we put them on a really rigorous regimen. Where every other day. They only four hundred calories. That's not something that can be maintained as a lifestyle. 'cause it's very hard to maintain your body weights with that in these overweight. Asthma patients over two months it had profound beneficial effects in improving their symptoms. Their airflow in their lungs My lab we measured indicators of oxidative stress and inflammation in the blood which went down not right away but between two and four weeks of initiating that every other day metabolic switching regimen case we published that study then as approached by michelle harvey who's in england and works with women at risk for breast cancer because of their. They're overweight and also have a family history and she came to my labs. He'd seen our work in animals and And there's also some work in animals suggesting that fasting can be beneficial in suppressing cancer growth. So anyway michelle designers. Study where we took these women hundred women and we randomly assign them to either. What's now called five to intermittent fasting or we had a control group where we had them eat breakfast lunch and dinner but each meal had twenty five percent fewer calories than they normally take in. And because we donna calculation that the long-term calorie intake would be similar in the two groups. The group beating six hundred calories two days a week versus the girl eating three meals every day but reducing their calorie intake over six months both groups of women lost about eight percent of their initial body weight and both groups had improvements in glucose regulation and other health indicators but the women on five hundred men passing headed greater improvement in insulin sensitivity in las more belly fat compared to the group. That was counting calories if you will every meal then what happened is producer. The bbc michael moseley picked up that study when published it in twenty ten or eleven and he did a documentary for the bbc with jared in twenty thirteen or fourteen. It came to my lab and walter those lab and krista verities lab and then so that on the bbc and then people being in uk guide interested in intermittent fasting. And then all of a sudden. There's all sorts of things showing up on the internet on intermittent fasting. So it used to be before the work in the early two thousands that if you go letterman fascinating the top heads actually be scientific papers now if you go go. Intermittent fasting dislike a bunch of random people who are have some angolan salon. But there's now that the good thing about data. There's a lot of interest from mainstream medicine. And i wrote an article well and twenty nineteen together with a former post doc. Rapid kabo a review article intermittent fasting for the new england journal medicine and the editors invited us to write the article for two reasons. One there had accumulated sufficient number of human studies Fasting particularly in overweight people to merit a coverage of it but the second reason was that many physicians are being approached by patients asking the physicians about intermittent fasting and in in some cases maybe many cases some physicians. Really don't know much about it..
Impeachment: A Daily Podcast
"the new england journal medicine" Discussed on Impeachment: A Daily Podcast
"That those vaccines are very effective against the delta variant especially against preventing severe disease. Which is the outcome that we most care about. We care about whether we are prevented from getting such severe illness that we ended up hospitalized or dying from nineteen we also know that getting the vaccine substantially reduces our likelihood of passing on the virus to others. Now the delta burien that it probably is in people in larger quantities and that's why is transmitted more easily but getting vaccinated still substantially reduces the viral load. So i hope the right lesson is that vaccination is still our best and only way out of the pandemic and also then we need to how these other public health tools. Already including the tool of reimposing indoor mask mandates which. I really hope that people in this country. I think there is tennessee in the us. Think that well the pandemic is behind us. It's really not especially for those who are unvaccinated. But i hope that people remember that even if you are vaccinated there are still a small chance that you could contract cova nineteen and pass it onto others but also that the more kkob is in your community the more likely you are to be at risk. And that's why. I'm making sure that we still have those tools of reimposing indoor mask mandates is important this nurse we welcome your questions about the delta variant anything about vaccines and children vaccines and young adults and vaccines and senior citizens or anything else. Relevant for dr. Lena win at six four six four. Three five seventy to eighty six four six four. Three five seventy to eighty or tweet. A question at brian lehrer. Dr got a question. The other day from a listener in his nineties vaccinated in january and asking if he'll need a booster shot soon since july is six months and some people say it could be that soon that immunity weekends. I told them you were coming on. And i would ask you. So what would you say to that. Six month vaccinated senior citizen. What i would say that is that right now. All the data point to immunity lasting for quite some time. We don't know exactly how long it lasts but it should last well beyond six months and probably in two years. The there are some some exceptions so people who are severely immuno-compromised for example may already need a booster shot in fact there was sustained paper that was published in the new england journal medicine pointing to the effectiveness of eight third booster shot for people who are recipients of organ transplants on immunosuppression. That a third booster shot could really help to increase their immune response however forever we are immune system. There are more and more studies that indicate that armenian system remains very robust. Because it's not just about the antibodies it's also about these memories be cells that could produce antibodies very quickly if we are exposed to covid nineteen now though studies are still ongoing about when people are going to need booster shots. You'll need boosters. Under two circumstances one is if immunity is does appear to wayne again right now for generally healthy. People does not seem that. That's that's the issue with the vaccines we have to is if there are variants that arise that may make the vaccines less effective. Maybe we need a specific booster to target those variants right now the vaccines that we have seem to be effective against all the variants of concern that we know of that said the cdc the fda actively evaluating their circumstance..
The Peter Attia Drive
"the new england journal medicine" Discussed on The Peter Attia Drive
"Couple of minutes here. So struggled through power lines and cancer. You've come to wrestle with the pitfalls of epidemiology. What brings you into the den of nutrition and living in la fantas near the beach. Doing freelance science journalism and working on screenplays. Probably still not making any money so my friends were wrong about. At least my ability to get rich. Writing screenplays i call up my editor at science and say look. I got to pay the rent next month. I need a story. I could turn over quickly. The have anything. I could write that all generate a paycheck and so researchers have just reported there reporting on the first results on the dash diet dietary approaches to stop hypertension. It's low fat. Lots of fruits and vegetables dietary approach and the papers coming on the new england journal of medicine and they have a pre print. They have a pre release copy. It's embargoed so i should write about this. And you've never written about nutrition and health science never written about nutrition. No okay so he's pretty desperate if he's giving you this because this is a little outside. It's one page in the magazine. It's not a lot going on so the way you do one page story right. You call up the principal investigator. If the articles have been published yet you ask the pi interview him you recipe for the names of a couple of other people who know about the research could comment three interviews for one page doing your job so it takes a morning to do the interviews and afternoon to write the article today and a half. I get my rent money. What i didn't know about this article is that had been leaked to science in advance ended had been leaked with the list of researchers who i could interview. This is what year this was. Nineteen ninety eight or nine. My editor gives me the list. Doesn't tell me it was leaked or if he did. I didn't pay attention. So i get the article. I call up the principal investigator. Larry appel johns hopkins. I interview him. I asked him for the names of people i talk to. I call up one of the people on the list. This is a former president of the american heart association at the university of alabama birmingham. And this person tells me that they can talk about the paper or the loser. Funded and i say it's this. We're talking about a diet trial. The new england journal of madison. Nobody lose funding for talking about that. It's going to be not gonna come out to after the embargo the woman she refuses to talk to me. She won't tell me anything i said. Look if there's something wrong with this paper let's go off the record not for attribution like woodward and bernstein and the garage with deep throat. Tell me what's wrong with this paper. What the issue is. Because if you don't tell me i'll never know and i'll report it incorrectly. She refuses even to do that. So then i get off the phone with her. I call up one of the people. That larry appel. Johns hopkins is given me. And he's a researcher who darts yelling at me. This guy is the the grand old man of the field. I don't know this any starts yelling. Mary over the phone that there's no controversy over salt and blood pressure and i am not calling about tom. Blood pressure professor calling about this diet trial that lowered blood pressure in the new england journal medicine and he continues to berate me that. There's no controversy. So i get off the phone with him and i call up my editor science. I said i had an american heart. Association former president refused to talk to me because she would lose her funding. She said if she did. And then i had this other guy yelling at me that there's no controversy over salt and blood pressure when i'm not writing about song blood pressure. There must be a controversy about tom. Blood pressure that. I know nothing about so. I'm to write up this article. Get my paycheck. And then if you don't mind to look into this assume salt pressure controversy and see we're missing and i spent the next nine months reporting that i interviewed about five people for one magazine. Article turns out that it is one of the. Most vitriolic controversies in the history of medicine and even though already by nineteen ninety eight. We'd all been eating low salt diets. America for fifteen to twenty years. It was clear that the randomized control evidence never really supported the intervention and that was backed up by a lot of bad epidemiology and research is assuming that associations were causal that weren't and that were even questionable associations to begin with and while i was doing that story this fellow who was yelling ma. I like to joke. He sounded exactly like walter matthau over the telephone by the way he's still alive. He's about one hundred one years old so while i'm running him down as a scientist that's argue Evidence that may be. He understands nutrition and diet far better than i do anyway. While i was interviewing him this walter matthau character was clearly the you know i spent ten years of my life. Studying bad science was clear. This guy was one of the worst scientists. I'd ever interviewed my life in the bottom five. At least and i thought i had interviewed the worst. He took credit not just forgetting americans to eat less salt but eat less as well for the low fat diet. We had all been on since one thousand nine hundred eighty four so at one point i call them my editor and i said look. This guy was involved in this controversy fat controversy in any way fat. There's gotta be a story there. You're the message. From nobel dreams and bad science was that bad scientists. Never get the right answer. you know. it's just. It's too hard to get the right answer to go in being sloppy and slipshod and lazy and ambitious and get a right. Nature's and that kind. So i said you know what i'm done writing about salt. I'm gonna write about fat. No idea what the story is. I've been eating. I've been living in la whites and probably a fifteen percent fat diet. The would have been proud of me but if the dogma was based in any substantive way on this fellows work. There's a story there. And i spent a year writing that piece. I interviewed the hundred and forty five researchers and administrators for one magazine article. The big fat lie. No this was the soft science of dietary fat. So this was. The salt story was calm. The political science of saul political and parentheses and the fat story was called the soft signs of dietary fat soft and parentheses. They both won national association of science writers science in society award after you wrote these two articles one on the soft science of fat and the other on the political science of salt. What made you decide to go. Even further and write what would become perhaps the biggest and most controversial piece you wrote at least in the newspaper and i believe it was for the times magazine. Wasn't it new york times magazine. I wanted to write a book. When i was done with the to science articles on whatever was happening in medical science that could lead to these kinds of mistakes. Remember my obsession. As pathological science the nutrition aspect of it is just an interesting vehicle through which to explore. And i realized that if i did a book then i would go broke. I was married. I had responsibilities member. I had come out. Forty thousand dollars in debt. Just doing the cold fusion book was clear. I didn't work fast. And i didn't wanna work fast and that i would not be able to get an advance large enough to cover the time it would take to do the book so i was living in new york. I was having lunch once a month with an editor new york times magazine. 'cause among other things. We shared an affinity for the same local french cafe in the village and we would talk about story ideas and we decided it might be a good idea to see about balanced. Ask the question. What caused the obesity epidemic. And i said to the sky. When i was reporting the dietary fat story for science i had had met with a administrative from the nih. Who said you know. It's interesting when we told people to go on low fat diets in nineteen eighty four. We assume we really didn't have the evidence. Support the heart disease connection and the message. My story is a never got that evidence but we thought if nothing else would be telling people to avoid the dentist calories in the diets they avoided fat. They'd lose weight and that would take care of the obesity and overweight at the greatest risk factors for heart disease and he said lo and behold now obesity epidemic and apparently people stopped eating fat and eating more carbohydrates in that ghanem fatter so. I always had this two hypotheses for what caused the obesity epidemic which you can see in the day to begin somewhere between one thousand nine hundred seventy eight nineteen ninety-one and it coincides with two fundamental changes in the american die was embracing of the idea that a low fat diet is a hard healthy diet so carbohydrates in general go from being considered inherently fattening. Which is sort of the conventional wisdom until the nineteen sixties and then they get transformed into heart healthy diet foods and you may be too young to remember this but we all stopped eating butter and started having pasta and bagels every day and low and behold everybody starts getting fatter. The other thing is high. Fructose corn syrup cayman nineteen seventy seven. Seventy eight type. Fructose corn syrup fifty. Five comes in which can replace shar in coca cola and pepsi and by nineteen eighty-four saturates the beverage industry and this coincides with the beginning of the epidemic and people.
Dr Ron Unfiltered Uncensored
"the new england journal medicine" Discussed on Dr Ron Unfiltered Uncensored
"Be one hundred twenty thousand backseat adverse effects per year. We're going so the real number may be one point two million vaccine adverse events every year magically calls as a family of ones who are buried along with nope frame of investigations. Don't know guilty press your medical journals around the world which utd published been trials of medical doug spill legal rights law asia after page. Doctor i probably read it. Allies were medical votes. Is that the world. It is simply no longer possible to believe much of clinical research that is published with you want to judgement. Transit positions. were far tatum medical guidelines. I take no pleasure in which i reached slowly and reluctantly over mike to deck is editor of the new england journal. Madison marsha and compare that one from the father of science if anybody can claim to be an expert even when they have no idea whether something is published in places like new england journal medicine size nature. Sal or jama you know. Generally that is white wealthier. View editors editorial staff journals really a series a. Take things so seriously. They routinely published studies of medical of the real epidemic. That nobody's talking about. But i have been talking about john. Battled for just talking about. It is a sickness injury on by doctors. Recommending death by modern medicine by dr harlan. Be and she's updated since even worse than we think they increase about winning five thousand and as we said a lot of factors. Don't being so. it's really underestimate. What's going on with over testing over treatment. twenty percent Medical care is unnecessary. Necessary including twenty two percent of prescription gums. Twenty five percent of metal eleven percent of procedures. Why because doctors feel malpractice. Feel patient pressure so again message. Even if the drug is backed by size does not guarantee that it's affecting likewise at alternative jeevan that has not been published in a medical journal does not mean it's unsavory ineffective see why you have to be educated being accelerator a body and you know modern medical model undervalues or ignores diet and lifestyle factors such as all of these sleep accu signs electromagnetic deals. Didn't simon debater. So we have a health issue have to make use all the resources available to you including your own sense of common sense in reading and prudence and caution when evaluating a new drug claim. It's likely to be more worse and if you are phasing. Health channel tallies seeing it competent conventional position. Who has a serious condition is just beginning. Probably would be your vestiges to identify. All of i natural health consultant. Someone who really understands hell could get to the root of the problem. I just put a band aid. There are so many satistics here. I don't want were you. Medical long is destroyed. You can go by the numbers number after number. Joe show accuracy rate reporter really. A reporter has reported on obits about all the fake epidemics. 'boudzhi has has been control all the vaccine because he has raced but on the market whichever falls go hand braces already know the credibility of the world health organization. Suspect suspected. Best so gentlemen. We'll be talking about this as time goes on medical. Profession is heating causes. Fm underestimated even by the people reading before because doctors do not work side effects and the deaths of the her of exceeds the who only ten percent of the report. Anything else now. i've also been talking about covid. How why you'd have to the euro reading. I mean today. It was reported that a portuguese nerves die.
Breaking Biotech
Gilead's Remdesivir Efficacy Still Uncertain! Is Stemline Therapeutics a Buy?
"So I'm glad to be back and I have a great show for you all today. We have some real spicy stuff to get into. Some of them have commented on twitter. But yet it's it should be good so I'm GONNA start off today by talking about some biotech news. Some little updates that we got some press releases and then a follow up by talking about Gillian ads at Rim decively data. We're going to touch a little bit. On the New England Journal. Medicine study that they published followed up by a report that was provided by our friends at Stat News. So that's going to be good and then the final topic. I WanNa talk about is stem line. So you know. One benefit of being in this volatile environment is that there are buying opportunities right now and one that I do see is a company called stem line. So we're GONNA talk about them and why think thereby right now so with that? Let's get to some of the news that we saw this week and first thing I wanted to touch on his after sys mostly because I just talked about them in the last video but we saw actually in the last couple of weeks that the FDA has authorized after says to initiate a pivotal clinical evaluating multi stem cell therapy in patients with Cova nineteen with induced acute respiratory distress syndrome. So some of the stuff that I talked about in my previous video was that I wasn't sure if the face to that. They're currently undergoing with their collaborator. In Japan was going to be a pivotal study. And it looks like it will be for the Japanese system and then this study that they're launching that they launched in the last couple of weeks is going to be the pivotal study for them domestically here in the United States so the primary endpoint is ventilator. Free Days Through Day. Twenty eight and they're beginning to open sites this quarter so I'm not sure exactly what that means in terms of when we can expect data. I would think maybe late Q. Three probably in Q. Four we'd see some data for this which could be a big boost for the company. Also what we learned in at the risk of opening another can of a drama this company they announce a public offering a twenty two million shares at two dollars and twenty five cents for about fifty million dollars in proceeds. I did say that I was expecting them to announce another offering and that is what we saw earlier than I expected. I really thought that they were GonNa wait until maybe later in the year to do this but while the songs doing okay I guess it's a it's an opportunity to do so so with another fifteen million dollars in cash. This should give them another six months or so and you know if they do see some good data from this pivotal study it would likely boost the stock quite a bit more before they have to go ahead and raise money again. So that's after says. I'm still saying on the sidelines. I'm still not super confident. In that data we originally with their phase one so I have no real sense on whether or not I think the date is GonNa be positive but I hope it is that this can get rolled out and it can actually start helping patients that have covert nineteen and areas going to move quickly to immunogenetics which is a company that kind of fell off my radar ticker symbol. Is I m you? They have a compound called says a to Mab Guven Akin and yes. I did practice. That's all I can say. A properly for metastatic triple negative breast cancer and I kind of talked about is the potential for this drug. It's it's a unique formulation so that they can really target the cancer cells and hit them with this tailored that is toxic to all sales. But because it's tethered to something that specifically targets cancer cells it would primarily affect them and kill them so the primary indication they're looking for is triple negative breast cancer and they had done in a sense study to confirm their previous face through results and there was some concern with safety but the sense that he was actually stopped for compelling efficacy. So that's great news for them the PDF date is June. Second of this year. And we'll see if the FDA is going to go ahead and approve the drug so that they can search treating metastatic triple negative breast cancer patients. They have a plan readout for your cancer in the second half of twenty twenty and they're also still enrolling patients for positive her two negative medicine breast cancer so I think that that trial read out is going to be particularly important for the company. And I'M GONNA keep them on my radar and pay a little bit better attention because I think that if they do see positive data there. The company has a a much larger patient population. Go after so Yeah so it's good for them and hopefully they'll see a positive result at the PDF eight anime. Keep an eye out for that trial moving on. I WanNa talk a little bit about Amarin. Because they had their earnings report while ago and what we learned is that they're cute. One Twenty twenty revenue beat estimates at one hundred and fifty million dollars and I had said previously that. I thought their estimates were sandbagged in anticipation of better results. And that is what happened but unfortunately none of this matters because they do not have pan protection in the United States given the ruling that we heard a little while ago so regarding to the appeal and the generics the CEO is not expecting at risk launches. But they are willing to file an injunction. I've talked about that in the past. This is not new news but they did also say that. In the event of an appeal loss Amarin would be willing to launch a brand engineering version. So this is an interesting strategy in order to allow them to maintain market share in the space because if they launch a generic version immediately. You know by the time another generic comes to the stage Amazon's already going to generic Kinda solidifies their position in the markets. There's not going to be really an advantage to patients taking a another third party. Generic other than Amazon's now the only issue with this is that the generic price is going to have to be competitive with the other companies. That launched generics as well. So in this way they're gonNA lower the amount of total revenue. Get but there's a lot of uncertainty in the company. I'm still not sure what I'm GonNa do with my shares. The stock has bounced back a little bit. But you know if they don't win appeal I assume they're gonNA see further downside until we actually start to see the kinds of numbers that start coming in given the new pricing of generic version of Amarin. So we'll see we'll keep you posted on what I do. I'm tempted to buy a little bit more and lower my cost basis by I'm I don't feel great about that either. So we'll see all right. Let's talk about Gilead. Everybody so first thing I want to touch on with Gilead is this New England Journal. Medicine studied that they released regarding the compassionate use of Rendez severe for patients with severe cove. In nineteen so Gillian been at the forefront of the media when it comes to this rendez severe drug that they're hoping to get approved and they initially had rendez severe offered only as compassionate use for patients as is still undergoing phase. Three trials right now so some people who are really severe severely affected by cove nineteen could apply to to take severe and what they did is they published a study with fifty three patients who had taken it under this program and really it wasn't a placebo controlled trial so for me. There's no real conclusion to be drawn. They said that a majority of patients were discharged. But because there's nothing to compare it to doesn't really mean much Another thing that's worth complaining about for the studies that they didn't even measuring viral load. So we don't even know if patients that were taking Severe head lowered viral loads in. You know we could figure that out by comparing baseline to treat a data. But they didn't do that so it's Kinda left in the dark here. The company itself has terminated a study in China with severe patients because of low enrollment. And they're awaiting the publication of these data to announce in-depth review the result. So that's one thing that we can also look forward to see is the data that we're getting from this low enrollment patient population in China. And they are doing a mild to moderate disease study in China. So that's still ongoing. Takes been seeing on twitter. Pretty disappointing a lot of people complaining that the New England Journal of Medicine shouldn't publish the study given that it was you know. There's a conflict of interest and there's no placebo and you're not new to academia. You know it's a cartel. The big name journals really only published stuff. That's like really hot off the press type thing. So of course there's huge problems with this study and Gillian's not even shy to mention them in the discussion so they clearly outlined limitations of the study. And everybody that I've seen on twitter isn't really taking that into consideration they think Gilead just willfully blind to the fact that there's no control. Obviously they know that. And if you want to throw the New England Journal Medicine under the bus or publishing this year but throw the entire institution appear review under the bus. It's a horribly flawed system as somebody. Who's coming from academia? I've seen this all the time you know. These journals are a cartel that gate keep science. So that unless you know people or your science is so particularly compelling that they'd be willing to publish it but if you WanNa talk about the academic system and publishing. Let's have that conversation but to call out this study in particular is being. The true hope written the true problem in the world of publishing. This is not the one for you
Radio Surgery
More men with low-risk prostate cancer are forgoing treatment, study finds
"And it's looked at a three decade long study about prostate cancer treatment, and it was a comparison study. So so many men think oh, you don't need cancer. Are let's say so many men are led to believe I mean, historically were all led to believe if you have cancer, you should get out of your body's you get a treated out of your body a cancer in your body's not going to do anything useful. And for some reason men have been pushed to do nothing about cancer. Well, here's a study a three. Decade-long study that looked at treatment versus no treatment for advanced prostate cancer in men, they looked at what happened to the men who got treatment versus didn't get treatment. And the study suggested that the benefits were in the men who got treated for advanced cancer. And it was published in the New England Journal medicine. The study started to see three decades have started before nineteen eighty nine and they'd go on to note that prostate cancers and number two cause of cancer deaths in men number one is lung cancer. There's one hundred sixty four thousand cases of prostate