35 Burst results for "THC"

How Cannabis and THC May Affect Your Heart Health - Healthline

News, Traffic and Weather

00:44 sec | 1 d ago

How Cannabis and THC May Affect Your Heart Health - Healthline

"Millions used. They actually be hurting their hearts. And a new review of studies the organization finding cannabis use may be linked to an increased risk of heart attacks and heart failure. There have certainly been reports of people with heart rhythm abnormalities, hospitalized patients who have More complications of their heart attack, for example, when they're hospitalized with a heart attack or heart failure, Dr. Rose Marie Robertson, the deputy chief science and medical officer of the cautioning more research needs to be done after multiple studies found smoking. The TH E and cannabis could shrink blood vessels that feed the heart and lungs. I think

Cannabis Dr. Rose Marie Robertson Deputy Chief Medical Officer
"thc" Discussed on The Church of What's Happening Now

The Church of What's Happening Now

03:01 min | 2 months ago

"thc" Discussed on The Church of What's Happening Now

"A look at what they got often press in Church and get. On it delivered right, the asked get ten percent off your first order. I can't help you any more than that. I'm going you the biggest fuck and favorite meal life. 'cause I'm Tanya you into a supplement. That's GONNA keep make your fucking head because you know how Joey does I'm out here to fuck around if I can push it, I fucked and use it. talked to you about something to to. Real quick you I forget. God dammit. This always happens to me when I'm fucking. Doubt Anyway. Listen like I told you the beginning of the podcast. You're wearing a fucking wig. Come on, guys. Listen I dye my hair. When you look at me, you know I die my head, I don't die because I want. I die 'cause I do videos, and when I do the fucking whitehead videos I told you. I forgot to put the ink. into the thing, that's how stupid I am telling. You guys. I'm not genius. I got the same problems gotta, but anyway we all got a problem and we all have a problem. We could deal with it now, either you could fuck and wear a wig, or you can let your hair grow long and put that peace and make make a stink that you had. Stop it! We all read to the bullshit. Face the facts to other three guys in a lose their by the age of thirty five. That's just the way it goes. It's hereditary I. Know a lot of us a balding and I don't mind looking at this new head. Let me tell you something guys. If I see a toupee coming at me I'm going to fucking call one of those fucking Lewis to steal it from you add. We all know what's going on. The George Jetson fucking head door right over one hundred thousand guys have used keeps. Keeps is tremendous. It's it's FDA approved medication at ahead of the price. You get treated online by a real doctor and you don't have to go nowhere. Hang onto. What got an prevent? Hell us which keeps let's lump fifty seven years old. I'm father time from the future. I'm telling you to do something today starting to lose my fucking. Cut My hair wasn't that easy? Because I've lost a dome, only the side keeps growing out like early from the fucking student like. The other one Larry I think is his name is, but let's. You'll need to go through list I had a friend I grew up with. That, he was so ashamed. He was losing his hair. He was spray painting his head. Don't do that. Let's let's keep the hey. You got and plant seeds in the wrestling Fuckin- head so he can make you look like and Paul. McCartney on the cover letter be right. Let's start with fucking keeps. That's how we started like I, said over a hundred thousand guys played for keeps with keeps, and treatment starts at ten dollars per month, but Since, June I i. know you're fucking broke. I'm going to take care. I'm going GonNa, give you the first month for free. Okay, prevent hair loss. Go to keeps right now keeps dot com slash church again. That's keeps.

Joey Tanya Larry I FDA whitehead George Jetson Lewis McCartney Paul
"thc" Discussed on The Church of What's Happening Now

The Church of What's Happening Now

07:12 min | 2 months ago

"thc" Discussed on The Church of What's Happening Now

"Is I. Don't know what this is, but this I got to fucking weed from fucking urban trees the other day. Multiple this the we gave Chris son, to get over fucking Kovic and the stand. That's how good this year this. Not Deck about deck about a week later it's after school. I knows days. I used to go to school to three. Change and shoot up to the bar would cut through the woods, shoprite and walk nine blocks to my mother's bought and I'd earn I. Talk Put away. I play stickball outside I get a slice of Pizza Pinos pizzeria. fucking. Sandwich shop what I choose to go up there and one that walked in and all those Cuban business owners the sitting that. The one guy's name was sad pussy buoyantly. AM fairly a bunch of Cuban owners. And they're talking about what's going to happen to be dumb talking Cuban cop. And then make you nervous you just you just recognized. I just was like faulk. These. Cuban this Cuban guy is getting under the skin. I won the what's that? What's the move here? Wonder what the move is? There's all these guys talk a good game. I won the what the fuck and move here is. I heard him saying he's got to go for Kim. Thought that the DOT. And not even a week later, and I wasn't. A sixth grade wasn't libidos glasses I remember when I got a class that. The teachers were talking in the hallway. I went home, and I thought something had happened. I got on my bike that day. I didn't even have a chance to cut through the woods and I rode my bike up, which was nightmare in those days. You got those monster. Hills North Bergen. And I got up there when I walked in all those Cubans are solid Brayton. Drinkin- Falcons Norton, and that like they shot the cop last night at rapid taxi, I guess he went to make a payoff, and they fucking wooded bullet riddled this motherfucker that. An, my friend Mario Arias was Mas Vegas he's friends with the guy that was in the cop put car with him. For reason, the COP car could nope, not that the car got jammed. That's where I get to help his fucking friend Oh. They just put a statue up of that cop about. Two or three years ago, maybe they showed a picture of his son with the statue up in Jersey. Jersey But that crime. Changed the face, a union city, they closed my mother's bar. Because things had to happen because that. COBB got killed, but the cops didn't really they they. They caught a Panzi. They arrested a Panzi maybe around. Mile Away with gun to this car. And they arrested him for the. Then the right guy. Is Crazy. And I know forgot. That's when I realized that. Some people. Don't fuck around. Well not only that they go after fucking guy. They went after an undercover cop. I mean that's. All this stuff is showing me like you always hear like the always heard like. Oh, the Jews could could've taken over or like the back when we had slaves here like if they there was so many of them that they could have taken over if rebelled and stuff. Like what with the amount of people that are protesting? Those cops were scared. Everyone wanted to attack every detective in L. A.. Every cop is on the job applications that have been canceled. Every police officer is at work minimum twelve hour days crawling. Police gear if you're a detective, all those cases have been dropped. I know for a fact that preparing Hudson county park on Tuesday. In New Jersey northern New Jersey Newark had hard time last night. From all this you know. This is what people that was a micro situation. Yeah, that was one that they didn't even let it slip. And I'll tell you what the cops never really prosecuting they but because. Of the problem. Now they would dealing with a problem. This guy's fucking apart fucking shit. We're all making fucking nice little cash shaking down. These Cuban bookies nobody saying not not even them. They know that there's a price to fucking pay then not even complaining that happy. They buy us a drink. They offer male. They don't want to go to jail either. Make it as a harmless fucking vice, nobody's getting raped in the ASS nobis getting fucking Harvey Nobody's GonNa Bookmakers armless combines. There is a degenerate gamblers that's when it becomes a vice naturalness, theft and stuff that and I've been there. He's My rob Michael Julius. Them Bookie, right? You know money so I do get aspect of it. But. I don't even know fuck. No but I think that's. What you're talking about Jews nine hundred and the protest had no idea all I know is that. There's one police officer for four hundred thirty two fucking people now, I. DREW THAT'S TRUE That's the that's the allow police. To people ratio at National Guard dot calling them for the National Guard is he and I WANNA. Thank by the way a lot of people reached out to me last night on facebook and twitter check in Hawaii I even wrote a couple fucking jokey poos last night because. I was watching the fights. But at the same time I was switching over. To the riots and I couldn't believe what I was saying. And when they were talking about the fair tax district, and then a friend of mine called me and he goes hey. Are you busy? I know he goes. I met down the candidates to get a sandwich bring. That was a joke that shit was going on in front of Canada's yeah. So Canada's is a old Giudicelli that Sinatra fucked and leader for that. You know like everybody got the dixie that. Whatever. But that's you know when I was in my poor wife, I looked at her face. Because my poll, wife qualities yeah three weeks ago in Hollywood, because you see that big glass right that Hollywood choose. That has begun does ever write. I think they'll be ride and she goes. Eventually these people can't keep living like this. That's button and not and some rioters. God's Blessing Mad Masks I. Ask. It's a good time that was blocking masks. Fuck, mascot that was some Luna's had Dick on, had nothing on. But back to the store with my mother taught me. Like that scared me. My, that situation scared me. Let me know that somebody could disappear that fast. Yeah..

officer Jersey Panzi Canada National Guard Hollywood Pizza Pinos Chris son New Jersey faulk Harvey Nobody Hills North Bergen Brayton Kim Hudson county park COBB Mario Arias New Jersey Newark theft rob Michael Julius
"thc" Discussed on The Church of What's Happening Now

The Church of What's Happening Now

02:02 min | 2 months ago

"thc" Discussed on The Church of What's Happening Now

"Who knows what the fuck is going to happen? Greeting some podcasts Ville. The church. What's happening now? Monday June I rent this do motherfuckers. He's got the rent. Louis! The church is brought to you by and welcoming keeps. Let me talk to you people. These fucking guys is two thousand twenty and they're walking around with a fucking Oregon. You ever seen these guys, or then you got the guys that look leave the headlong and cut the hell side then they're missing an action. They make up a story about getting mugged and they come back. Looking like them Beatles the whole new how to have. These, guys, you ain't nobody. You're not fool nobody so stop in fact. When I see a do with a wig I say a prayer fish, 'cause you don't have much left and day now's. Had It's two thousand twenty. You gotTa fucking rug a raccoon. You fucking get it together. Face to fax to other three guys will lose their by the age of thirty five I know a lot of people were balding and like I. Don't mind looking at a smooth head, but let me tell you something guys, if I see a hugh a toupee coming towards me. I'm walking the type of person I am. Am We all know what's going on underneath that fucking little George Jetson head. You're not fooling anybody with that rug. You has ding. It's at the end of the fucking world. The best thing you can do is get ahead of it. I'm fifty seven years old. You know what I'm saying that I'm father booking time from the future and I'm telling you to do something. Hang on and prevent what you have. What loss you have with keeps. Get online by a real doctor. FDA approved medication over one hundred thousand guys at played for keeps with keeps. Treatment starts at ten dollars a month, but since you know Joey. I'm giving you your first month. Free do me a favor. Stop it! Stop it! I know you don't you don't feel good..

Louis Joey hugh FDA Oregon George Jetson
Growing Weed in the Garden with Johanna Silver

Cultivating Place

08:35 min | 2 months ago

Growing Weed in the Garden with Johanna Silver

"Joanna. Silver is a gardener. Writer and editor formerly the Gordon Editor at Sunset magazine. She is a regular contributor to Martha Stewart Living. Better homes and gardens and the San Francisco Chronicle the author of the old dry garden on the garden and legacy of famed California plants woman. Ruth Bancroft this week. Joanna joins us to talk about her newest book growing weed in the garden. A no fuss seed to stash guide to outdoor cannabis cultivation out now from Abrahams press cannabis in California has been legal for medical use since nineteen ninety-six and in November of Two Thousand Sixteen California. Voters approved the adults use of Marijuana Act to legalize the recreational use of cannabis the use sale and possession of cannabis over a certain level of THC remains illegal under federal US law that said according to a recent report on NPR thirty three US states currently allow for some form of sale and consumption of marijuana and of those more than twenty states have designated the cannabis industry as essential during the corona virus outbreak from her shelter in place with her young family in Berkeley California. Joanna joins us today to shine a brighter light on the often confusing. Growing we'd as Gardiner's welcome Joanna. Thank you so nice to be here back with you. The last time we spoke we were speaking primarily about your first book the Bold Dry Garden and this new book is something of a An adventurous kind of Tangent. Or like offshoot from your original. Garden writing work. I want to start though with your current relationship to plants and the garden world both personal and Professional Joanna. What do you do everyday tell listeners? More about who you are and what you're up to. It is so nice to be talking to you again even just anticipating the conversation that I would be having with. You got me just like thinking about life and anyway thank you. Just thank you for having me. Thank you for making all the room to talk to people about about exactly this. Their relationship to plants I am home now as you know. All non-essential workers are and I am doing the very essential work of raising my son who turns three in July and In a non pandemic situation spends most of his day in a share So we gardened some But it was more like gardening light and now that we're home together. I am gardening heavy and doing with him I salt. I was already going to have a vegetable garden this year. I was already scaling back on the. We'd I'm only really growing at this year to continue to write about it It's a it's a really fun plant to grow et Cetera et CETERA. But I really have this urge to grow fruits and vegetables with my son and so even though that was already going to happen I dug up to maybe like eight by eight feet by thirty inch. Beds right in the middle of our meadow grass to with him to create more space. So as I talked to you he's asleep. There's dirt all over my hands and I'm feeling really really connected to the hard honest Labor of garden creation and it feels so good so good and you. You touched on a couple of things already right there. One being the fact that many of us are home as quote unquote non essential and yet in this moment so many people have turned back to activities and connections that are so essential like our own attachment and connection to how you survive how we make our out. We make our lives not just livings. And that is in raising our families and cultivating art pieces of land. So okay I'M GONNA I'M GONNA have a go back just a little bit before we dig into the structure of the book in in some of these levels on which you got intrigued. Many listeners will remember the bull dry garden. But just for those who. Don't give us a little background on you. Where where were the people? And the places and the plants that grew into a person who would wanna be a person that wrote about gardens and gardening with her son as a matter of both principle and practicality so I got my start farming in college after traveling so really interested in food and food security. I had a very meandering path and ended up in the editorial Test Garden at Sunset Magazine. Back in the Menlo Park days through to the Oakland and New Test Garden in Sonoma's county days and went from outdoors at the magazine to indoors. Writing and editing and timber press reached out to me looking for a bay area writer to write this book idea that they had about Ruth Bancroft S- Garden cactus in dry garden in Walnut Creek California and I pitched myself because I was young and ambitious and so I wrote a book about. Ruth's life and Roots Gardens. She just passed away actually also twenty early twenty eighteen late twenty seventeen at the age of one hundred nine And so just a couple of years before that. I wrote this book about her life and her garden. I think the fun one of the fun things for me as a gardener and garden communicator journalist person is seeing so many come back to gardening and recognize it as this essential thing that it is and that you and I and kind of die. Hard gardeners have has always known. And we've been advocating for now. You also indicated in this first question this sort of interesting Almost conflicted feeling about growing weed. And I think it's a perfect segue into the conversation for us on this on this program. People have been telling me that I should do an episode on weed for the longest time. Because as you note in your introduction to the book it's one of the largest crops in California and many many people are interested in it and it has this deep historical ritualistic medicinal blige intimate like wait and Gravitas to it but that is so blurred by the the other baggage that comes with it that I have stayed away from it until now because I was so compelled by yearbook and the way that you handled that year and maybe it was a little bit more of researching documenting and writing about this project. You took on as a as an assignment not necessarily a personal passion but an assignment and So we really kind of want to get into that the I just WanNa say by the way that your documentation of life at home with your To almost three-year-old Garden intern as you call him on. Instagram has been in total pleasure to watch in. Its true sort of honesty. Raw dirty fingered honesty. Thank you. It's been. It's been a massive creative outlet for me. Yeah Yeah Okay so. Tell us about this book. Why this book how did it happen? What made you decide to take on writing a book about growing weed in twenty seventeen? I had a baby and I was headed back to work You know six ish months later back to Sunset Magazine Garden editor where I thought I'd have the job for the rest of my life Kathy Brazil before me held the position for forty years and I was all set to go back. It was the week before. Maternity leave was over and the place was bought by private equity in lost my job I felt desperate to keep writing and working and reached out to everyone. I've ever written for asking for assignments Just to keep going to feel some forward momentum and a former editor in chief of the magazine. Kitty Morgan Worked at the Chronicle San Francisco Chronicle and I reached out to her until I wanted to write for her you know. The chronicle does garden design edible gardening whatever and She said you have a new baby. I bet you don't have time to do lunch But I may be called her bluff and I was like I totally have time to do lunch and met her for lunch and she. It was right before recreational use went legal and including recreational growing in California. And she was like I have this whole other idea for you. I want you to grow wheat in your backyard and documented as a gardener. I think at that time everyone like it was coming but it still felt even more taboo than it does now. We were all sort of figuring out how to talk about how he felt about cannabis being something that we can talk about and And so I told her I didn't know where to get seeds. And she said emphatically. That's your opening line and it was supposed to be for this part the separate website run by the Co Chronicle called Green State Which has since been folded into the magazine or into the newspaper and it actually got got lost its funding for a while but kitty was so dedicated to me that they ran the series in the food and wine section on Sundays and I worked through this ten part series for them on growing lead in my backyard as a gardener starting from knowing nothing to having a big crash course in the plant yet everything about the naming and needing to forge new contacts. I had I was starting from zero other than my years of experience being garden writer And a gardener no for sunset.

Cannabis California Joanna Sunset Magazine Ruth Bancroft San Francisco Chronicle Sunset Magazine Garden Writer And Editor New Test Garden United States Writer Martha Stewart Marijuana Berkeley California Joanna. Silver Co Chronicle Abrahams Instagram Editor
Linda Klumpers PhD on Cannify, Cannabinoid Pharmacology, Cannabis for Pain

The Curious About Cannabis Podcast

08:11 min | 3 months ago

Linda Klumpers PhD on Cannify, Cannabinoid Pharmacology, Cannabis for Pain

"My name is Linda Columbus and I am a clinical pharmacologist. I have a PhD in clinical pharmacology of Cabinets. And I've been studying cannabinoid since two thousand six. You're listening to the curious about Canada's podcasts. Everybody's Jason Wilson with. The curious about cannabis podcast. Thanks so much for tuning in once again so today. I'm really really excited to talk to Dr. Linda. Trumpers clinical pharmacologist. That's been studying can have an AIDS cannabis for quite a while and then we also have a shared interest in education as well So this'll be I think a great conversation. Thanks so much Linda for being willing to take the time to come on the podcast today. Thank you for having me. Jason is really great to talk to you too. Yeah thank you. Yeah so For those that may not be So familiar with your work. I mean one thing. I'll point out is that you are the brain behind. Kfi which which is an online Quiz and also kind of data gathering tool to help point people into The direction of research around certain things related to cannabis in can avenue to try to help steer people away from all the hype and sort of hearsay Which I I like a lot but Beyond that do you mind just describing a little bit about your background and kind of what got you into studying pharmacology. And then specifically what got you into cannabis. Oh sure so. I've always been very interested in so many things. And one of those things is the brain and that's why studied neuroscience and sometimes you make decisions in life based on the things you like And sometimes she choose things based on the things. She don't like and one of the things I did not like about studying neuroscience and it's really a personal thing. I'm not trying to judge but I had a very very hard time. Working with animals The mice rats were were so cute and I said yeah a big problem with working with them. Playing with them whistle fine with mice. 'cause they bite you but rats crawl into your sleeve and stuff so so. I found it so hard to to work with them that I thought I I want to do something else. That is still euroscience related and that is actually how I got into because if you study drugs in you months actually gift consent right. Yeah exactly yes. He don't meet to decapitate them after they're done. So that was a more friendly way of Still being able to study what happens in those brain of braids hours While yeah Leaving the animals alone so that it's always a combination of things and this is just one of the of the. Yeah the topic says really important to me not working with animals and science pharmacology biology medicine. It's also interesting and with pharmacology. Newman says will come together. And Yeah exactly. Yeah and now regarding cannabis in particular. I must honestly say. There are a lot of people in in cannabis that really do this. Because of their passion for the plan their passion for cannabis. And I'm very interested in plums. I'm very interested in a pharmacology of cannabis but there. There is a lot of interesting blondes out there. A lot of interesting compounds in cannabis is one of them. There are a lot of interesting geological systems in the body. The Endo cannabinoid system is one of them. And how I how? I got to work with Cannabis actually was because In amid nolte's pharmaceutical companies were racing against each other to get the first avenue bounds on the market which was actually notes a agonised like Dat for example because that has been in the markets incident one thousand nine hundred eighty s but wasn't antagonised so a impounded binds the same places state seed us for example T T. Sta compounded cannabis. It makes you feel high but then it does the opposite effect and the whole idea behind those compound classes whilst to a fight obesity to treat addiction. And those were to go bounce it. I start working with and if you onto dusty school bugs in healthy volunteer. She will not measure anything. You will only measure something if you I activate the system and then try to block system. It's just WANNA give one single-dose and see what happens. So we activate the system giving THC and is one of the ways. I got involved in cannabis research giving t t innovations later trying to study what? Thc does on your brain how you measure that with Marai. Studying various administration methods with with cannabis so in relation five eight sub lingual oral. That is how I got into cannabis research. Yeah that's so exciting. Pharmacology is such an exciting field. Because it's like this giant puzzle to work out all of these interconnected systems that are working together to produce effects on the body. It's something that has always interested me and on different levels and have you always had a passion for that kind of thing of trying to understand what's going on in the body and I know you said you started out with neurosciences. Trying to understand what's going on with the brain but is that kind of where that comes from like even as a little kid where you kind of interested in trying to understand and. Yeah Oh yes oh definitely I love this question because yeah it is just amazing to me. I see the brain as part of the body. So if something happens in the body changes you can also find it in the brain. A very ex- yeah Good examples for example menstruate menstrual cycle in the in the period before menstruation. People feel different. Why is that now? There's this whole discussion about the the Gut. Brain Axis said the microbial. Yeah exactly so that your intestines have influence on your brain as well. So that's all interconnected behaviors ferry ferry important and interesting to me at high school. I was always fascinated by peer pressure. People also give me if I wanted to do something because everyone did it and I did and do it and they were just surprised but everyone does it now but I don't want to. Why why would I have to do that? Why I also smoke arrived. I also use Moscow our GUT my hair and and and the children for Mike loss would not always listen to me but if someone from a higher lawsuits and I was fascinated by why. Why do you care? What do people are already so influenced by peer pressure by group pressure and I think that a lot of that now has to do with the brains as well and drug skin influence your behavior. A lot of people use L. Goal to socialize because it takes away there a threshold. I do not drink alcohol personally and I've never really had a fear of talking to strangers but I recognize it is very very important in society and therefore brains behavior drugs bodies. It's always fascinated me.

Cannabis Jason Wilson Linda Columbus Canada Dr. Linda Obesity KFI Aids Newman Moscow Marai Mike Loss High School T T. Sta Nolte
Murphy Murri on Cannabis Extraction, Hydrocarbon Safety, Aquatek, Standardized Extracts

The Curious About Cannabis Podcast

09:20 min | 4 months ago

Murphy Murri on Cannabis Extraction, Hydrocarbon Safety, Aquatek, Standardized Extracts

"Hey everybody this is Jason Wilson with the curious about cannabis podcast. Thanks so much for tuning in once again so today. I'm joined with Murphy. Murray a fellow cannabis educator and also a cannabis extraction consultant. And today. We're going to be talking about Oh let's see what we get into primarily cannabis extraction. Thanks much murphy for being willing to come on the podcast. Yeah absolutely thank you for having me. Yeah Really Soak. Our paths hadn't crossed Before now So this is kind of been long awaited for me as far as I followed some of your work and senior classes like from a distance. So it's cool to finally connect and and Talk about common interests for those. That aren't familiar with some of your work and your background is kind of diverse Do you mind kind of sharing just a little bit about some of that background. What led you into getting into specifically like the cannabis chemistry and extraction. And all the work that you're kind of focusing on now yes sure. I started in the canvas industry When it was fledgling in Colorado so we had the caregiver structure in two thousand nine and we started seeing retail dispensaries. Open up but there wasn't licensing for it and It still kind of mimicked. What California has going on in at the time in a lot of ways and so You know I got involved on the retail end. I lived in the Vail Valley and we wanted to sell high end cannabis products do those high end medical patients and in two thousand ten licensing started and in Colorado that meant vertical integration so being from a marketing background and working on the retail side of things. I had no preparation for an extraction lab and certainly no preparation for large-scale consult a cultivation and so It was all just something that was kind of thrown us and we had to get involved. I did my best delegate where I could but the lab was one of the hardest ones to To delegate out because they're you know a lot of people had grown for decades but there wasn't much for extraction historically You know like a lot of people were doing bubble ash but that is not even in the same department especially at the time. We were We were just starting to see things like amber glass which was shattered made for methanol. We're starting to see the butane honey oil and we were still really just calling it honey oil at the time and not even really referencing how it was being made because everything was still a big secret for a really long time which is part of the reason why education so important to me because the first three to four years of. I can't miss career especially in the extraction world. There was no where to get good information. There was a couple of hard to navigate forums with a lot of code words and screen and it was really difficult to use that information in a practical way and not having that. Chemistry background was certainly a disadvantage. But at that time we were doing chemistry. We were barely extracting material. We were cannabinoid behind. We are not purifying anything and we have no analytical testing to support it so you know the concentrates that we made we had no potency data on. We had pesticide data. We had no heavy metal testing. We you know I couldn't tell you. How many milligrams of THC or anything else? It was all anecdotal. It was all descriptive and you know I look back that and just get anxious about all of the products that I made and sold that I wouldn't do today because we just didn't have the tools so fast forward a few more years and the Internet makes things a lot easier. You know. Ten years is a long time in terms of Internet development and so more information became accessible which is good and bad. A lot of bad information became accessible. But what is more relevant is that we have the social media aspect of it and so now I could actually network with real humans. Ange as more states became legalized. People were less afraid to actually share what they were doing and Like real consultant jobs started becoming a thing and so we started to talk a lot more and develop methods. And that's where I kind of got into the extraction space You know in a very much more serious way. Because we started to actually have real standards to pursue and I started to meet the type of people who were doing things that I wanted to emulate and from there I got involved on the equipment and things in two thousand fourteen. I started working for extraction tech solutions. Which was one of the only hydrocarbon equipment manufacturers at the time and I started doing private consulting from there. I just became fully immersed in in the world of extractions so from You know just straight up cannabis extraction to also the burgeoning hemp industry. And we've just kind of gone all the way from black oil to white powder right. Yeah the last few years yeah. That's it'd be fascinating to kind of see that laid out on an image timeline. Memories can be scary sometimes. What is it that Particularly about extraction? Now that's really driving your passion to kind of continue that focus in that arm of things I think one of my favorite things about extraction has always been that You know it's it's very objective you know. Once we started bringing out a little testing into it and started actually doing chemistry labs. It was really rewarding because I could perform a process could get results than I could repeat those results Compare that to like cultivation. Where the you know every step you take today. You say the results of that weeks months ahead of Point so there's no instant gratification and cultivation whereas extraction is instant gratification every thirty minutes I get to see the results of what I've achieved and so It feels very productive and it also gives me a lot of room for error which is very exciting for me because I love the experimentation of it with cultivation even just having a table that you try out new nutrients on can affect literally the rest of the garden whereas with extraction. I can have a new idea. I can try new piece of equipment. I can tweak a process I can make these changes. You know minute to minute. Day to day and get to evaluate the efficiency and so the potential for growth is phenomenal Because it's exponential every day. Try something new and you know. Every new test result gives me ten more questions to go chase down the rabbit hole so it is constant change in very fast moving which I find personally rewarding. I'm the type of person that rearranges my furniture. Often extraction is nothing but change. Yeah Yeah I could see that. That'd be really exciting. To be caught up in that accelerated process of refinement. Refinement technologies and process and everything. You really get to see it unfold. In a way that that's unique when you were learning about extraction. What were some of the resources that you found most valuable to kind of understand what you needed to do to take things to that that next level I know skunk farm is obviously one resource that we all probably know pretty well. That's a huge one Or some others that you those online forums were enormous but through those online forums. I actually got to meet really competent people. I think both ten years ago and even today the mentorship for finding someone smarter and better than you is the most valuable lake. I look back on my career to some specific individuals who brought me in and were willing to share. What at the time was like trade secrets? You know The things that we didn't discuss Out Loud in part because it was a legal but also in part to keep our brands. Unique and those people were enormous for me I had a couple of chemists who were involved early on that were really helpful in explaining some of like the basic safety issues that I would never have even thought to ask questions about probably without their help Not to mention just some. You Know Industry Pioneers people like Nick Tana of essential extracts. Who you know was willing to teach me how to make bubble Harrison is kitchen and get involved in this industry when it was still barely an industry. We were barely for profit at the

Cannabis Colorado Consultant Murphy Jason Wilson Nick Tana Murray Vail Valley California Ange Harrison
"thc" Discussed on The Curious About Cannabis Podcast

The Curious About Cannabis Podcast

12:26 min | 5 months ago

"thc" Discussed on The Curious About Cannabis Podcast

"Yeah we need as a society all this proliferation of Fido cannabinoid plugging I several other people. I've talked to have Sort of mimic that message. Should that one of the best things you can do to support your into avenue system and and it's the message that we've all grown up with exercise more and eat healthier and eat healthier thing I think is a very interesting piece because You know we're learning that a lot of plant compounds interact with Indo Cavanaugh. System and our foods over time have become less and less rich. In a lot of these these fighter nutrients I would do that including things like flavonoids and certain Turpin and things like that and one example. I use as corn. Giving the HELOC. Ubiquitous citizen are diet that at one point corn was bred for a high oil content. And one of the big Turpin constituents that oil is offline and Beta care off lean interact? Cb Two receptors and and possibly other components of the new cabinet system and that was some dietary interaction with the ACS that we were having early on. And then Between like I think it was like the forties in the sixties in that time started to breed out those oils because At the time we didn't have a way to value them. It wasn't really in our consciousness that that was something we needed to care about. So as food product corn started to become less and less abundant in Beta. Care OFF. Lean and other compounds I'm sure a similar story is true for a lot of foods And what's interesting about the corn pieces now? Researchers have learned that having those Turpin rich oils actually helps reduce the need for pesticides of corn. So now they're starting to breed it back in And so it you know it may be interesting to see with combination of exercise and finding finding fido nutrient rich foods And regardless of the fact that we don't know exactly what's going on but just knowing that they are interacting with the ACS and that it's generally recognised now by the folks that are studying the most that the system is essentially a foundational physiological systems connected to everything else and it's it's driving a lot of homies static processes and get a little anxious talking about homeostasis. Because I think it's a concept that people often mischaracterized but it. It has something to do with that overall balance of the body and so absolutely we used to be more active our foods used to be more fighter nutrient dense and we move around a lot. Less our foods are a lot blander more blankenship compared to what they they used to be. And and so. That's perhaps where this all fits in is you know if if there is a deficiency that would explain a lot of that and and being able to stimulate that system and a proof is in the pudding. I mean over the past forty years. We've got better with air quality and water quality as a nation right and we less cigarettes but I mean you look at the movie stars from the Eighties. Like old baseball gloves. They're all like forty years old. Yeah and you look at all people in the cannabis industry. And they're all like a bunch of babies off. Samya Nice teeth and know like pretty decent overall kinda health because they used cannabis all their lives or twenty years and so. I look at that as one fundamental. Yeah empirical piece of evidence and there's interesting research showing like THC stimulates metabolism. It changes the way. Glucose is managed in the body and I interviewed Dr Ethan. Rousseau and he was telling me about some new research being done on the Gut microbiome and cabinets in showing that THC tens to promote a healthier balance of microflora and the Gut. And I've obviously it's now generally well known that the gut microbiome is a critical piece of the immune system as well as The nervous system and everything. Well that's with krones and.

Turpin Gut microbiome ACS cannabis Indo Cavanaugh krones Dr Ethan THC Rousseau baseball
"thc" Discussed on The Curious About Cannabis Podcast

The Curious About Cannabis Podcast

12:48 min | 5 months ago

"thc" Discussed on The Curious About Cannabis Podcast

"Everyday stuff what Dr. Oz keeps pitching raspberry key tones or whatever really is. There's some evidence there they really can't put together. Studies that say reduces breast cancer. But you know it's individual individual really and what cannabis cannabis. We want to be as like a lifestyle who wanted to put different types of candidates in as as as you feel fit like you'd get vitamins. Kanta Mondays from ingestion. And so just keep on mixing them together and never let your body become accustom To one particular thing of THC Beulah selected become accustomed to it but These cannabinoid are flavonoids or different substances. Just be as bouquet and you know the one CD if put it in your system. It's not gonNA work after a while in there and your system is just going to ignore this overpopulation. That's part of You know the way our molecular signaling. Networks are set up is if there's too much signaling going down then your body says. Oh and he did turn that volume down we need to pull some of those receptors. You must not need them get so much you've got so much and there's been some interesting Casual Studies and some formal research has shown. You know if you need to break your tolerance with cannabis go to something that is a different. Cultivar slightly different chemical profile. And you know and regardless of those those other compounds in the buzz right now is all about Turpin but just like we were saying that people are GonNa go from CD to CBGB's n. t the same thing's going to end up happening with these chemical classes. That people are going from Cavanaugh. And now they're all about her opinions and they're moving towards flavonoids now and they're gonNA keep rediscovering what we've already discovered about plants. Broadly you know that. Kimmel classes are in all sorts of plants. And they're very interesting but so from an extraction sense. Yeah exceptions going away from all these complexities say it was fun to have the. Turpin moment right usually. It's not just about shatter now. I have these liquid products but now they're trying to make them lighter and lighter in color note in that's going to be stripping now all the stuff that touches you tongue makes it ignite is the same stuff that you can strip away. That looks like a color and so what do our products are products in coloration or like beers more. Yup come from hops Cannabis and hops are pretty close. So if you look at your beers you have red. Orange Yellow and the porter is dark right but we like those red orange and yellow colors and you mean an people to see through them. But I could show you could bring out some samples because we're at our facility in the light coming through them his different. Yes Oh working with Dr Harrington out of Ohio nebulizer concept of spectral fingerprinting really simple and the plate reader you just signs the UV light. You know how used to analyze. Dna. Sue The you'd go through the spectrum and then it absorbs and let's pass through proteins. Carbohydrates all that so these substances should absorb or let light pass rate. And so you should get a fingerprint. So you should immediately know. Does this product wax or interfering molecules in it that will interfere with my experience and bioavailability and so maybe we can make a light that we can shine through And some sort of way to record. They have some of these devices marriages science and of course in science. You have all these devices and the worst. The conversion to chemistry cannabis is. Can we put my brand on this and sell it to people in cannabis as a novel concept but they all exist in science? I mean that's that's been the racket in canvas testing all these technologies. That are being proprietor. I don't have any proprietary stuff chemistry and may experience and we have coca-cola was I'm going to tell you the exact sequence but they're going to protect that flavor and taste and everything. So maybe that's the concept this texture and the taste and everything. We want to protect the ketchup. Heinz wants to protect the bottle and the look. They don't want anybody interfering with catch up as you want right but ours our own catch ketchups not proprietary. Yes so when they say a proprietary blend of solvent. What are you talking about? A twenty five fifty twenty-five that's our proprietary blend. It's a secret so it's quite funny but spectral fingerprinting could we do advice? Put THE PRODUCT. Shine a light through it. It tells you even like broadcast your phone APP. Is this product where Sixty Bucks Product Twenty Bucks is. Product would five bucks. And that's all I ask from this community produce any products you want. Just make sure. They're appropriately priced for the value that whoever's buying them as getting so there's GonNa be a bunch of dollar to five dollars products on our market and but there's going to be elegant places for Nice cakes and pastries and exactly. Yeah the whole spectrum is going to be there in that's technology that's that's really interesting. It's a that's a really cool. Quick qualitative measurement. Basically you know just looking. You don't have to get super quantitative about about any of the stuff that can you in front of the oven. There's like four bottles right up front. Lake Lava kicked GMO. And everything. Show you what? I'm talking about a little bit about light. So when we do our process how we quantify or quality things in science you pass through them you put them on shells you separate them. You run them through juicy columns and heat them up you bend them around magnetic things so we started looking at the light. That's coming through our products and nobody else could show us. You could have you know live resin. You can have a distillate jar. They could look in a peer depending upon their heat as our products but rain shine the light through our products and they have a unique spectrum. That comes out because they're effectively pure. Yeah they don't absorb these articles that absorb that way to explain that. Yeah Yeah and so We're going to try to hitch onto that and try to with all of our products show. How pure they are and then get into the game or co two dozen or raise other things. They still have wax. Yeah well yeah that would certainly be interesting if in the future at dispensaries or wherever folks into buying strikes in different states but if there were A tool like that in the same that for flower folks are looking through magnifying and smelling everything that with extracts they have some mounted light or something and can compare these spectra and then and then even some you know getting around to kind of What you're you're sort of pointing toward is a new Kind of qualitative standard. That you could actually come up with some ranking or A A spectrum of qualities that the imagined. No labs on it do that for me because there are no new company. Who can't meet that? Quality is going to say lab should do this tester. I should have this data so that we know. Yeah because it's not so that's not a common theme that's only a theme to us because we have that higher ability to reach that second tier so another thing is they have hand-held you put your nugget in you get the USB reader tells and those things they're not accurate the any of the same result every time so whatever thing we do it really has to be spot on and reliable and then that really puts your customers trust in in whatever it is so eventually we wanna make sure that everybody can come with product table. But there's gotta be some metric some qualitative measure of how well separated who the resin from this extraction. Can How cute it? Down the line. How bioavailable bioavailable isn't if you put a Nanno emotion and do all these Nanno Paiko things to it and shove it in your just shoving it in a water soluble. Yeah Yeah and then it's disassociating your body and then you're calling it now. I mean you know. That's not what we're talking about. We're talking about every molecule being unperturbed inaccessible under your administration regimen. And you don't necessarily want one hundred percent of can interpret all these other things to be by available I mean we've we've co evolved with the idea that you know a lot of can we ingest. Do just get excreted. And that's fine because it doesn't take much to you know get in your bloodstream. Read sites of actions and cause profound changes to the body And so it's something that I am that actually there are all sorts of things about the industry that makes me a little nervous is not that. I like necessarily think there's GonNa be a some sort of crisis or anything but I'm keeping an eye on it but Attempts to change by availability and things like that so we don't really know what some of those effects are going to be so the COO acetate. Yeah I said it was going to be the first thing that killed somebody in cannabis so people were making this molecule and it's one hundred times the efficacy of THC which. I don't know you're having a problem with the efficacy. Got Okay so what happens is it gets a stream. Somebody is the amount of product they use custom with. Teach see with this product. That's one hundred times more and they the crash themselves out. And then you have your first step in. Thc because everybody's T- cannabis is so safe. How could we do any wrong? And then you add the o Acetate to and now you're doing wrong so there is i. Keep anytime I see come up. Oh we're doing huge. Ceo Acetate. This is a new thing. I try to squash it immediately. Industry like you'RE GONNA kill people with synthetic canaveral. We've we've dealt with these ultra potent cavanaugh and seeing what they do make people pass out throw up. Immediately people crack their skulls. You know people that especially you know so. We mentioned earlier off camera that I'm from Mississippi. Something was really common less common now. But you know in Mississippi where prohibition is still so strict and no one wants to fail a drug test but people still want to use cannabis and there's not always necessarily a sophisticated understanding of how quote Unquote Legal. Bud K. Two or spice. How that's different than cannabis and so a lot of people are using these herbs with synthetic can avenue in Spain on them Comes up athletes. Yeah Yeah it's it's very common show up at the police station all act out. It's very common in high schools with athletes. That don't want to fail drug tests and stuff and Yeah we already know that their major problems with those things that Er visits. Are you know. That's something that doctors do have experience with particularly in southeastern states and in the Midwest and stuff Where that's exactly. Yeah and so absolutely. I'm I'm with you there that we've got to be really careful about introducing. There's nothing wrong with the non cannabinoid in cannabis. Let's just start getting them right. Up to increase of those minor cannabinoid breeding. We can get them. All back the cannabis plant is a treasure chest. Yeah if the Bio Pharma found this Amazon today it'd be the Elliott investigation of our entire lifetime. WE FOUND THIS MIRACLE. Drug Plant Bio chemical factories. It's amazing so they're all in there so we just gotTa start teasing them out. That's what my upset necessarily characterize to see in nineteen fifty and here. We are just starting to see a little bit of CBD and there's half a cent. Nobody wants to around half a century. Many.

cannabis Cannabis breast cancer Cavanaugh Dr. Oz Turpin Midwest coca-cola Kimmel Dr Harrington Heinz Nanno Paiko Lake Lava Mississippi Spain Ohio COO Bio Pharma Ceo Bud K.
Daniel Hayden of Extractioneering on Carbonated Extracts

The Curious About Cannabis Podcast

09:31 min | 5 months ago

Daniel Hayden of Extractioneering on Carbonated Extracts

"Am delighted today to be able to sit down with Dr Daniel. Hayden of extraction nearing or as most of you probably know extraction hearing here in Oregon Thanks so much for being willing to sit down with me and talk today for the podcast. Thank you yeah. I'm really excited to to see what's going on. It's it's funny. You may or may not be surprised how hard it is to find knowledgeable extraction chemists or scientists. That are doing extraction. That are willing to actually talk to me. There are a lot that seem very very protective of flu idea. Yes and there will be some protected parts of course and we wish we could be further along with the company and when we are further along we should be engaged about some of the more protected. Parts let's talk about the science. Yeah Yeah as you as you continue to grow and evolve definitely keeping in the loop and we can do drop INS and Educate folks more on on some of what you're doing Into GIVE people context. I know some people watching this and listening or probably somewhat familiar with extraction hearing already from pretty solid instagram following. And that sort of thing but for those. That aren't so familiar. Haven't seen any of your work. Can you briefly described a little bit about your academic and professional background and then a little bit about the work that you're trying to do here sure Bring it up into two parts of my background. Is I went to got my bachelor's degree for In biotechnology at Rochester Institute of Technology in upstate New York at the time in nineteen ninety. Four that was when flavor saver tomatoes came out in genetically modified organisms really came to space and I really felt I was interested in natural products but I really wanted to get into the technology. If there's somebody with a like minded who wants to go well I wanted to get in and understand. genetic modification so I started to pursue that for bat. My Bachelors I came in contact with cannabis at the time in the use. And what it meant to me in. So I married the concept biotechnology together with natural products like biodiesel biomass for cardboard for. Would I got into him in the late? Nineties and my thoughts about how I could contribute biotechnology and hemp and specifically oil seeds. But there wasn't many opportunities as a graduate student. You tell me your background in Mississippi. There's one other lab in Indiana Illinois but didn't really work with the plant itself and so I said well if I just worked with plants in genetic engineering and rare and unique plants It will help when it comes to canton. You'll be ready so I went to the University of Hawaii. Just forecast myself our way and work with these plants that are weird and these tissues that protect them from all these environments in the tropics but we need to investigate them and so you couldn't just work on these things that the kids they're giving for corn and for other sciences. You had to make new chemistry and extract nucleic acids and really my PhD is about extractions. So they explain to you what the meaning of a PhD was in. Its own piece of work to contribute to your field and I was like I got seventy pages on how to extract from this anthem rubbery plants. Yeah she's and I didn't understand it then the context of it but the you know I got my publication. I got each and then I went into biofuels. Oh interesting so at the time. They're really hot topic In really biodiesel but I got swallowed up also slow stick but that was tissue culture with we switch grass working with the USDA understanding how government operates and policies and procedures and health codes and environmental safety laws etc and so also working with it really expensive instrumentation rise again and hoping that comfortable with all those kinds of technologies and so the tissue culture is really born there and working with sequencing I got through that and thinks along verbose discussion but a into post doc for UC Davis in this was on sequencing of an oil see. So now we're getting closer to non polar this oil body of a seed and why is it acting so unique and what are the genes involved and so I did? Three years really investigating The millions and millions of genes that are expressed in developing oats seed. Because the colonel is oil in it. Yeah Yeah and You know understanding what about gene expression made produce more oil and it. The scientist wants to say it's easy concept right the enzyme that makes it well like the. Thc The makes the THC. You just boosted your mortgage say knock it down and get less. It's not like that. Secondary Metabolism worked Lignin all my life secondary metabolism. That's where this pathway cannabinoid. It's stations itself and so We find out that the cells that make the product of question. We're had better metabolism. And when they were designed in the developing oats when they were lead there was more of them. So there's more of them to do the job of converting all the nutrients into the oil. Yeah and that's why you have a better oilseed. Not because the that one last step in making the oil. There's just more of that enzyme moral. So you know that concept. All those concepts in my background drove to the point of cannabis as say I can. I can see how that would all Come together and start to translate into a lot of the interesting things to investigate in cannabis. Something I I. Talk a lot about Concerning Cannabis's there's there's a good bit of research in a certain context. It's been done but there's still a lot of low hanging fruit when it comes to cannabis research a lot of things to investigate that We don't currently understand as well as things with like oats or corn. Some of these heavily heavily researched agriculture commodities and. Yeah and. There's a ton of work done on cannabis in the forties and the fifties and sixties mentioning Molecules To your imagination can conceive having these molecules in a larger amount and being able to interact with them It whereas all the progress right so we celebrate a few scientists Israel for coming up with context of crystallization of CBA. Who Wears the workmen for the past? Seventy Years Greg. What else is you know? Characterize all these other rare molecules. So this kind of translates into what I wanted to discuss you. The people you interview are in the medical field. And they're struggling to understand how to create context and it's because cannabis is so complex and then you don't have the right starting materials. They're starting material. Was a cannabis flower. Smoked and then all their patients treated the same. Then I would. I would listen to what's happening with this study. But it's just preparations concentrated preparations and then pills or whatever ingestion and so who knows what bioavailability. Oh yeah yeah I mean yeah. There's the bioavailability issue. There's also one thing that drives me crazy in trying to decipher a lot of the clinical data. That exists is the uncontrolled variables. So like you're talking about there's If they if they do happen to find relatively high-quality starting materials which is relatively rare and a lot of clinical research. That's gone on it. Still uncontrolled and inconsistent patient. Patients are really. You're looking at individual case studies more than like a you know a data set that can be validated in. Actually start to decipher wisdom at large. That would affect a general population. Now we're getting into the weeds batch to batch variability prove something with one batch and then they asked you to go back again or somebody asked for the patch to run it in their own samples. And it's gone it doesn't exist. They don't know how to qualify it on a consumer level in this marketplace with district cartridges. So Gosh yes same thing. Oh Yeah so what we have is broad spectrum. Full spectrum we have. I'm going to give you some random. Cannabinoid Z- And you're the better for it right. Yeah you know so you can thank me later. You know I've created some wild cocktail and I- bestowed upon you heal yourself. Thank you can thank me later. So we're really focusing on here and we've done you know of course creating this marketplace you have to create products and everybody's mind for the TC's so he's just GonNa move through but we want to make sure that moving we make sure we know what those minor cannabinoid Sar and the engineer them reliably so the customer goes back and knows this is a little bit more. Cbc In it for me.

Cannabis Scientist Dr Daniel Hayden Rochester Institute Of Technol Mississippi University Of Hawaii Oregon Usda New York Graduate Student Indiana Illinois Engineer Canton Uc Davis Greg Israel
Second Generation Genetics

Oregon Rooted: The Dirt Show

08:10 min | 5 months ago

Second Generation Genetics

"All right well we earn spur. Well I know I guess it's not spring yet but it seems like it's trying to be spring here it's trying. It's making me anxious. I WanNa plant some stuff. I know. Well that's everybody's implant fever. There's a lot of people out there right now. That are you know getting ahead of the game. I you know like J. B. E. popped in late February He's already like two or three weeks deep on his stuff so people are out there. Doing we don't usually do it to like March because they get paid like we. We don't need nine foot plans exactly so so. There's no really reason for us to go until about now but we are going to pop seeds now ready. I think that basically where we pop in our crosses from last year for sure because we gotta work those and I guess will pop you know whatever we decide on the ripcord jd short yep and then of course the rip cord and then yes. Of course the ripcord have to because I mean we've been waiting for that one mix monsters. Yes things are ugly. So we're GONNA Maybe considered crossing those two since since we have them. Why not why not? It's supposedly very very gassy. Now I told you about it. Got Me really high in studio when he brought it in for the Accu. I don't got to try it quite yet. You Jealous loop a little bit all right. So let's get right into the news just a few things here. The Bureau of Alcohol Tobacco Firearms and explosives issued a memo requiring gun dealers in Michigan to use federal background checks because current policy is allowed to many habitual marijuana users to illegally obtain firearms. Are Dirty. A bitch will marijuana use. Our SAMPHA CAN POT SMOKERS. Dammit figure shot a whisking come down. We'll sell your gun all day long you I. It's terrible. It's terrible I take that back. I mean it's just terrible that they're being so focused on a bitch you'll marijuana users as they put it. Yes exactly food and Drug Administration finally sent Congress Overdue Update on its efforts to formulate policy on enforcement discretion for CD products. Basically what this was you know? They've been getting dinged to come up with some guidelines for marketing. Yeah because people can make these crazy claims and they kind of have been. Yes I mean and if it's not crazy claimed CBD bedsheets in like. I'm surprised they haven't come up with. Cd TAMPONS AND CBD. I think they have some but they the CD pillow. Have you seen that one? You'll see okay. The pillow and I was the reason. I- pauses because of thinking about that. Yeah the CBD. Tampons probably not for a while. I could see that being well. It's they've offered you know they I was. I remember when we first went into top shelf and we were told by one of the guys in there about using I think it was empower on a Tampon and that his girlfriend did it. And so it helped with it helps with internal use of keeping cramps. Os sure will mean empower. That shits the bomb so. I expect their products to work. But I had a lapse or I'm like wait a second. That doesn't sound too crazy. But yes CBD pillow. I mean with snap crazy I mean. Do they surprised? They don't have like CD car seat covers and Shit Cagno. Ashdown way you drive in which I could see this commercial now. Do you have road rage order now? Our new. Cbd Car seat covers in road rage and your road rage now. Only twenty nine ninety five organ activists announced that they've collected more than the required number of raw signatures to put a drug decriminalization treatment. Expansion measure on the November ballot. This is what we've been talking about. We've had a couple of interviews. One was decriminalised and also we talked with a Delic and we referred number numerous times even read the news articles about how organs pushing for decriminalized drugs all of them really but You know Suicide in An and the genes is part of that to the signatures haven't been validated yet. Though so the campaign will keep collecting for more absolutely so basically. They announced Thursday that they had gathered. One hundred twenty. Five thousand signatures was huge I guess invalidated so that means. Probably no one's not. What responded back we know what that means is they gotta validate that the all those signatures are legit. So basically they WANNA make sure that they're not like duplicates or you know if they're forging signatures. I don't know exactly how they do that. Basically your son's nephew. Yeah well. It wasn't there but yeah just make sure that they're legit signatures. So their efforts is to go over. There already. Claimed ten thousand over. But they're going to continue going just to have some sort of safety They've had really good response though and not really surprised. I mean organ. I think is one of the places. It's going to be pioneering theologians. You know we didn't so much with cannabis but it seems like we're really pushing for pretty quick with the with people wanting to do this. Yeah this initiative is backed by the National Organization Drug Policy Action It's GONNA make it. Basically a civil infraction punishable by a maximum. One hundred dollar fine no jail. Time Nice and this is the problem. I just have to mention this. This is only thing that really bugs me about this and we did mention this previous. I think it was indicriminate. But the measures going to take funds not all of them but takes some marijuana tax revenue from schools education and redirect that to substance abuse programs. I get it. It's just education you know that was a great thing that we were getting from the cannabis taxes and we still will get that. I just don't know how much is GONNA be diverted. I hope it's not enough to affect education because right now everything's going well but as you know even with this money they still have short days at school They still don't. It's not like before where was five days of the same schedule. So anyway you could guarantee school. Most of the year is right right right and there wasn't extra days taken offer. It's really strange now. So even though with all this money they still do have some somewhat of a budget. I guess that limits their time at school A study indicated that THC might be present continuously even in non daily smokers at low levels even if the smoking occasions are separated by a week. Yeah I think there's so many variables like if you have a high metabolism that you know might be. You might be able to get away but we all know thirty days. I mean if you're smoking but I don't think that this study probably took an account. Niacin CRANBERRY JUICE. Lots and lots and lots and lots and lots of water. Yes yes you'd have to do that but yes. This isn't too surprising. The National Institute on Drug Abuse Released a solicitation for grant applications to fund studies investigating quote the effects of cannabis and cannabinoid exposure on the developing brain from pre and post natal development through young adulthood in humans and using animal models. Yes it has tested on animals as we should there is not a lot of. There's not a lot of solid evidence or studies on especially on developing prenatal babies. And we've talked a few times about our situation when we had our two year old so I think that stuff like this needs to be done and I'm glad to see this. I had to mention that as well too.

Marijuana Cannabis Wanna Accu National Institute On Drug Abu Bureau Of Alcohol Tobacco Fire J. B. E. Drug Administration Niacin Ashdown Michigan Solicitation National Organization Congress
There is so much we don't know about cannabis

Second Opinion

03:32 min | 6 months ago

There is so much we don't know about cannabis

"As best. We know one in. Eight of Californians smokes cannabis that puts California at position number ten in nine other states. People consume more of the drug. Alaska has the largest number of cannabis users followed by Vermont and then Colorado in the US. The number of marijuana users is nearly as large as current cigarette smokers. And as we've all heard cannabis in California is big business three billion dollars and that's just licensed sales given the huge us we know shockingly little about the real benefits of cannabis or about long-term harms most of what we heard growing up as teens turns out to be false. But that doesn't mean that there's not a lot more. We don't know old as any fifteen year old can tell you. Cannabis contains at least two active ingredients. Thc that's responsible for the high from marijuana and CBD Kenna by dial which may be an inflammatory and pain reliever both THC NCD can be smoked. Vaporized ingested applied as oils creams or patch is the route of administration is a key factor in determining how much of the drug is absorbed as doctor. I am not sure what conditions these drugs help. My patients claim. The drugs provide huge benefit for variety of conditions. Anxiety Insomnia blood pressure epilepsy addiction and more studies. Show that people with anxiety mood disorders and depression often self treat with cannabis to effectively manage symptoms with some opting for cannabis rather than antidepressants or mood. Stabilisers what we do know. Is that many of the drugs that doctors prescribe and some that are sold over. The counter have far greater dangers than cannabis products. What is urgently needed are studies that compare THC or CD in known doses to a placebo or other effective pills. Why because we know that about twenty? Five percent of people will claim benefit from a placebo drug. So the question becomes. Does the cannabis perform better than a placebo? We do know that. Heavy marijuana use can cause dependency which is very different from addiction. We also know that marijuana can impair judgement. Fine Motor skills pregnancy and certainly driving. But the dangers of cannabis are poorly understood. Cannabis is known to produce smoke with toxic gases which are then inhaled one. Very recent study published in Jama reviewed twenty-five moderately well conducted studies examining links between marijuana use and developing cancers in general. There were no or very weak associations with the development of cancer. It turned out that few people smoke only marijuana. Many also smoke. Cigarettes and the level of marijuana exposure is difficult to measure and reports from research subjects were biased because of their memory and recall but we really need to know more meaning. We need more research meaning. We need more federal funding to look at the risks and the benefits.

Cannabis Marijuana California Kenna Alaska United States Jama Vermont Colorado
NFL’s proposal for players includes 17-game season, limited THC testing

Afternoon News with Tom Glasgow and Elisa Jaffe

00:28 sec | 6 months ago

NFL’s proposal for players includes 17-game season, limited THC testing

"Changes coming to the NFL part of a proposed collective bargaining agreement between the owners and players association they would have a shorter preseason seventeen football games in the regular season seven teams from each conference would make the playoffs and we're told there could be reduced penalties for players who test positive for we'd really yeah well more and more states are gone in that direction so the NFL's saying T. H. C. I guess it's

NFL T. H. C.
Pot Making The Kettle Sicker

You Did What Now?

09:19 min | 6 months ago

Pot Making The Kettle Sicker

"Welcome to you did what now. A podcast where we discuss stories and science and tech the because ask exactly that everyone. Thanks for listening. I'm your host Stephanie. Educator and science aficionado Michael Programmer took A. How's your week Michael of the week? I'm having trouble this week. I need a drink is what I need to. Whiskey POD whiskey pod. I need a world coldest Martini rounds. Call this where do you get? The world's coldest Martini is a couple of his bar. Brooklyn a couple places. Is this a product called to this converge? I GUESS? From Jab from Japan as Super Cooling Magic it basically keeps water at like negative five degree Celsius water a negative five hundred Celsius so free is zero and this is negative five not frozen just has to do with the way the. I don't know I don't really understand. Visit science science soup. They add something to it or maybe alcohol has maybe aware freezing rate. I'm not sure no it's not The the the so this is just water. It's not actually the alcohols not actually yet cocktail with it. So the part of it. I don't have to dive into the crazy physics of it Look it up if you want. I'm sure it's out there. So it's a it's a frigid holds eighty like little vials of liquid. Which you're they're they're basically naked degree so they're already. They should be frozen but they're not for whatever reason the technology and the whatever they do so but when you pour it over your Martini or like on your drink or whatever you want to drink it basically instantly freezes so you get this little like stalactites owning my thing grow as of his little like crystal pile out of the water as it pours is like a little. It's obviously just water. But then you mix it with a Martini. And it's just like a cool little like instagram. -Able showmanship type stuff of point during our fancy over their new Yankees. Yeah I'm sure it's expensive too so but Everything Interesting Job. Yeah. Let's talk about. Do you know found this. I found a fact that I found very surprising to me. that over supposedly according to this one source over eighty percent of people will contract. Hp At some point in their life you heard of this vaguely. I people throw numbers around and help. And whatever the we've vaccine for that now though right. We do have a vaccine. Are you vaccinated? No okay well I mean vaccinated not for that and are you under forty five so far so far. I'm working on it then. You're still at risk of of being one of the eighty percent of people that apparently has Hp in the nation and so on then so in addition to that you know all these people are developing these STD's apparently but you know it doesn't doesn't always lead to that's the big thing with HIV is that it could cause some sort of some sort of cancer related disease in the body But it doesn't always lead to cancer growth by its of these eighty percent of the people that are contracting HIV. How what percentage of those people do you think are smoking pot? I probably the same percentage of the people that are smoking pot seventy-nine nine percent of the people. Hpv are also smoking marijuana. That's that's yeah no but This is this may be a problem because they've just found a study that does it. Cannabis accelerates growth of common tumor such as those caused by HP seller. It's the rural town. Okay I that's interesting for the most part people have said that there's really no side effects to pod and no danger so this is maybe that maybe it's not as natural inorganic as as people might otherwise suggest what can be organic. But that doesn't Sharia the growth of the ground and it's an opium can be organic natural. But that doesn't mean that it doesn't have any doesn't have any drawbacks to it. But it can affect affect your body negative ways so yeah you know and. I think it's interesting. There's a there's a big push right now at least here in Austin Texas to maybe not decriminalize but definitely lesser. The effects of people that are caught with small amounts of marijuana drug either on their body or in their car. And I don't know if at some point it will become legal here in Texas and other states. I don't know what's the status in New York is it is illegal in New York. Don't say legalize it just legalize I. I can't keep track. I don't know pot or not yet anyway. New Jersey. It's it's still medically legal in New York and New Jersey and supposedly and this is it's them for two or three years now. I remember when the last when we ousted Christie but everybody was saying that once we once Chris Christie and the next governor would pretty much Make legal like all around but so far that hasn't been the case. They haven't expanded that the legalization New Jersey for whatever for mostly. I'm sure political and economical reasons. They're just waiting to find me. The people that are GONNA MAKE. The money are waiting to find the right way to make money. Yeah well that's stuff. Well I I would predict that within the next five to ten years. It's just going to be nationally legal because it's you know it's already becoming legal and all these different states and I feel like one states. Make a certain legal. It doesn't take very long for it to become legal everywhere in the United States for the most bird. Yeah Yeah but you know. A lot of people argue that it's you know it has maybe health benefits to it. I know One person a friend of a friend who claims that it. It cured her cancer. She's decided not to do Chemo For whatever cancer she had and instead just you know. Smoke her whatever. Yeah I know it can in certain cancer patients it can. It can definitely help. Treat the nausea and other side effects saying they might have from but yes no. She actually claims it. It cured her cancer But that is unfounded unfounded unproven claim. Yes this there's some of those out there for sure but Nobody thought this article is interesting because it was it was. They found a direct link between the between the cell lines in they. Will they tested both both? The actual cancer cells the human cancer cells that that had a this cancer cancerous growth and then they tested the mice that they that they gave an HP virus to and then they monitored the growth of the cancer cells in those mice that were injected with THC. Those another question I had is like how do you? How do you have my smoke pot all day birthday? Give him little tiny tiny cigarettes to smoke gas. Just throw some teams like going to a party in the village yeah. That's an interesting job if your job is to get mys- holiday but no they they just They do the scientific way and inject them straight with teach C- So yeah so. They found that it actually interferes with cellular pathway. That stops the growth of the cancer Okay that's interesting. I guess it's still. There's a it's basically blocking your immune system from fighting the cancer. Yeah I mean it's it's not your immune system necessarily yourself have systems that will will shut down cell growth and that's how it should happen in cells the at some point the cells need to stop dividing right. So if you're if you have a cut on your arm and the cells around the cut need to need to grow go. They need to divine so that it can steal the wound. Right will wendo cells touch each other when a cell is surrounded by cells on every side of it there are certain triggers in their certain pathways. That will turn off the dividing mechanisms. So and what they found was that the thc in these cancer cells actually disrupts those mechanisms at turn off the cell growth and so yeah the mice that were The mice that were delivered. Thc had faster cellular growth of the cancer but this is the HP specific prompted. A prompt is not the right word. But the cancers caused by HP v S early all cancer not necessarily all cancer yet. They I don't know that they have studied other types of cancer. I think they were sitting specifically. Hpv related head and neck cancer. Because it is one of the fastest growing

Cancer HP New York Marijuana New Jersey Michael Programmer Yankees Stephanie Brooklyn HIV Chris Christie Austin Texas Texas United States Japan Opium Cannabis Nausea
Fatal crashes involving marijuana have doubled in Washington

Charlie Brennan

01:02 min | 6 months ago

Fatal crashes involving marijuana have doubled in Washington

"Loosely Hey what's going on in Washington state as we know marijuana is legal there yeah so because it according to Washington newspaper a concerning number of Washington state drivers involved in fatal crashes are testing positive for THC a recent use of marijuana according to new research from the triple A. foundation for traffic safety the share of drivers who after a fatal crash tested positive for active T. H. C. which is marijuana's active psychoactive ingredient that more than doubled since marijuana has been legalized in the period between two thousand eighteen and two thousand twelve the five year period before the drug drug was legal eight point eight percent of Washington drivers involved in fatal crashes were positive for THC that rose to eighteen percent so it more than doubled in the five years since it was legalized two thousand thirteen to two thousand

Marijuana Triple A. Foundation T. H. C. Washington
Inside the $148,000 Oscars Gift Bag: From a Luxurious European Cruise to Decadent THC Chocolates

Toby and Chilli

00:30 sec | 6 months ago

Inside the $148,000 Oscars Gift Bag: From a Luxurious European Cruise to Decadent THC Chocolates

"So the Oscars are on Sunday and you know all of them stars whatever get the goodie bags at twenty four carat gold vape pen is just one of the many luxuries items in the Oscar gift bags there is also a cannabis infused chocolate tasting for a group of twenty five thousand dollars worth of cosmetic procedures twelve days on a yacht to spas trips custom designed bulletproof doors that can get a year of matchmaking services all these nominees are getting a swag bag worth nearly hundred fifty

Cannabis Oscar
Inside the $148,000 Oscars Gift Bag: From a Luxurious European Cruise to Decadent THC Chocolates

WBZ Morning News

00:28 sec | 6 months ago

Inside the $148,000 Oscars Gift Bag: From a Luxurious European Cruise to Decadent THC Chocolates

"A twenty four karat gold vape pen just to one of the many items in the Oscars gift bag this year the list includes a cannabis infused group chocolate tasting twenty five thousand Bucks worth of cosmetic procedures twelve days on a yacht to spot trips custom designed a bulletproof doors and a year of matchmaking services all nominees receive a swag bag which is worth nearly one hundred and fifty thousand dollars the ninety second annual Academy Awards is Sunday

Cannabis Academy Awards
China's Bright CBD Future

WSJ The Future of Everything

09:13 min | 6 months ago

China's Bright CBD Future

"My name is Stephanie Yang. I'm a reporter based in our Beijing Bureau for the Wall Street Journal and I write about natural resources. How did you come to be interested in an CBD in China? Yes so actually. I moved to Beijing last summer and before I left I had a friend in the US who had mentioned you know. Oh Oh did you know that. China's one of the world's largest producers of cannabis and I had not known that I think a lot of people. Don't actually know that you. Can you just explain the difference between CBD THC Cannabis Ham. All these different words. Sure it's a little bit confusing. And I had a time figuring out myself when I first started reporting this but basically cannabis is the overarching name for the plant. And then underneath if the cannabis umbrella you have industrial cannabis or hemp which does not have high levels of the modules. I would actually get you high uh-huh and that's used more for textiles for rogue and for things like that and then you also have the drug component you know that you have the THC extract which is the psychoactive ingredient in marijuana. And then you also have this emerging trend of CBD which you know if you've walked around is New York or Brooklyn or lots of other areas they have these stores or even looked online. You can find basically anything with now. And what is is. It's the. It's it's another extract from the cannabis plant that provides supposedly a pain relief anxiety. Relief helps you sleep. And so it's more of like the relaxant accent part of marijuana that they're now marketing and extracting separately. So you followed up on that tip from your friend and not long ago. Oh you took a trip into two different areas in China that grow ham and they seem to be very different even though they grow the same crops so the two places that we went to were the long province which is northern China closer to Russia border and the other place was much much milder climate and it south south closer to the Himalayas. I wanted to get a sense of what people are doing differently from different locations since it really is only legal to be a growing industrial cannabis in these two provinces. Right now and Hailing Jong is the most recent one to adopt this basically saw. You know what they were doing down in and thought you know this. This seems really interesting and it seems like it's hurting them. A lot of money and I think Chinese farmers always looking for ways to reinvigorate aide and transform the agricultural industry and so the pick this up and they've been growing for the past couple of years and you were there at the very tail end of the harvest. Rest which happens by hand. So what's going on here. This looks very different than the cannabis plants. Over there that haven't been harvested yet. Tour's seventeen so one of the main differences between Chinese hemp. And you ask. Is that the grow it much taller here because while while the. US is focused more right now on developing CBD IN THC and high concentrations of those implants. China has a long history of using hemp for cloth textiles and so they need to grow the stocks. Really Long I mean that makes it harder for them to harvest by machine so a lot of this. This has to be done by hand with these large sites so Pharma's go in to the fields and the cut down each stock and then bundle them up. Does it smell the same way that we would kind of expect it to smell. It smells stronger here. Why is that so I think if I was walking past this field? I wouldn't wouldn't know that. They were growing cannabis. Because it doesn't smell the way you would think you smell marijuana or you know you walk into one of these shops. You one shot okay. Oh Wow yeah I really got that smell from it with a fresh fragrance kind of sweetened fruit in a way. That's very interesting and it also has very different smells at each stage of the production process. So you know when it's growing. It smells very fresh. Fresh and fruity and herbal. While it's being planted and growing and hasn't yet been harvested after the cut it down and the bundle it up when they leave it in the field to dry it starts smell a little bit different. I think Aleve Yeah. It's really strong. And then when you have it in the powder form in the fully dried form in the factory muscular China's been the wild wild out west for a long time. Jonathan Bench is an international business. Attorney at Harris Breckon. I've recently style myself. As the as the firm's international channel cannabis lawyer with a focus on China. Because I have the Chinese and I have the cannabis background as well. He says it hasn't been easy for farmers to make the switch using using cannabis in China is illegal and even growing hemp had been restricted until very recently the government officials have been okay looking the other way because Eventually see that that goes into products that get exported deformed dollars come back to China and China's economy can continue to grow so China has gone back and forth about how smart of a policy that is to permit local growth and export to export economy to grow at the expense of what is technically illegal in the country. Three so China has very strict drug laws because of their history with opium Chinese Communist Party. And I'll probably use the acronym see more than I'll use the whole name to the C.. PCP in China is is everywhere the CCP is always going to dictate how much social stigma applies to have growing to deriving MM CBD and other cannabinoid from him and whether or not they can grow marijuana which is hemp that is above zero point three percent THC threshold and then kind of generally how CD and other can have annoyed and cannabis generally will be seen in the Chinese culture so it's a very much of a top down planning planning in the government from economic to to social issues like hemp and marijuana China's narcotics commission last of last April said that you know in response. We're actually we're going to get stricter we're gonNA make sure that everyone who's producing cannabis within the country is following the rules so China's very unique in that right now all the that it's producing is actually for export so we we went to one of the extraction factories. Actor is of one of these companies that grows cannabis going on here the ship over to the factory. Once it's dry and the ground into a powder the mix it with alcohol and some other components and turn it into this paste and taken into the secret room that the actually wouldn't let us go into into what about over there and the end product. Is this tiny little vial of white powder or yellow powder or a mix between powder and oil and they all have different levels of CD content within them. You had to like wear these special clothing and there was. It seemed like there was a lot of to do due at this factory. More than you would kind of expect of a similar factory in the United States right. Yeah it was. It was a little bit of a process. I had to put on all of this protective gear. They wouldn't let me in without wearing my helmet and the lab coat and the covers over my sneakers and then when you get in there there are some in rooms where it's it's really noisy and there are security cameras everywhere so when you walk in in all the rooms the all feed into a central monitoring area that's also within the building. Why are the cameras everywhere? So that's another another part of You know the security measures put in place on this industry and so it's it's basically you know all these cameras feed in and so you can see every step of the process to to make sure that you know the THC is burned. You know all the plants in CBD is accounted for and actually the one of the managers there told us that the local. Aw Police Station said that they would conduct drug tests urine tests on the On the workers periodically. And so far. It's the hadn't done that yet because were were secure. And you know what they were seeing the cameras and the footage. But it's just because you know it's it's a very it's a very security intensive Business us to be in. Is that normal for China. I mean I think people might ask the question of what a Chinese factory looks like or is this really specific to two to CD and HAM products. This is pretty specific to CBD. I haven't I haven't checked out a lot of factories other factories in China yet but you know there was a lot. There was a lot of emphasis on security and cameras when we went to go visit

Cannabis China Marijuana United States Beijing Wall Street Journal Stephanie Yang Reporter Chinese Communist Party Himalayas New York Jong Police Station Jonathan Bench Government Attorney Harris Breckon Brooklyn Opium Russia
California tests find illegal vapes tainted with additives

First Light

00:28 sec | 6 months ago

California tests find illegal vapes tainted with additives

"Light buzzkill from California where medical officials announced that marijuana fade cartridges season illegal shops in Los Angeles contain potentially dangerous additives including a thickening agent blame for national outbreak of deadly long illness is tied to vaping but they also found that the illegal vapes confiscated in these rates typically we're not as potent as advertised sometimes containing just a fraction of the THC claims on the labels according to state testing results PAC of course the chemical and pop that makes the users

California Los Angeles Marijuana
The Potential Health Benefits of CBD

20 Minute Fitness

04:54 min | 6 months ago

The Potential Health Benefits of CBD

"So what is CB day CBD's otherwise known as dial on it say product derived from cannabis. It's a type of kind of aid. which are the chemicals that are naturally found marijuana plants but it doesn't create the high effect which is caused by the psychoactive psychoactive agent? THC which is another kind of annoying. So we've seen explosion in the number of CD products on the market as this growing awareness around the potential health benefits associated with CD lot of the perpetrators of benefits of CBD comes with anecdotal evidence. However there is some scientific backing as well to you back these claims up sir? CD products typically sold as oils or an edible forms such as via gummy sweets. Or a bomb you rub on your body and the health. The benefits that promotes by brands include aiding anxiety and depression procedurally from these and this is potentially due. To the way that they could change our brain receptors his response to serotonin which is a chemical linked to mental health so sorry to impacts of range of functions in the body includes a person's emotional state and feelings of wellbeing happiness answer keeping Serotonin levels balanced is often a key therapy for people with depression. Studies conducted that looked at the antidepressant like antibiotic end antibiotic like effects of caliber. Dial in which they reviewed several studies used animal models to see the impact of CBD on it being as I've is really really for us an antidepressant compounds and including lots of different variety experiments involving rodents to see its impact on the result suggested that did exhibit and Anti Anxiety Zayed's in antidepressant effect in the animal models discuss potentially this would also translates across into hearings as well and the author 2018 study. Found that it could also alleviate stress in rodents were the authors of that twenty eighteenth study also finding that the compound words without activating the brain's Endo cannabinoid receptors directly likely which may indicate that there's less risk of CBD becoming habit forming or addictive to people. Dr Perry Solomon who is the previous chief medical officer on founding member of Hello. MD also found that if you think about broadly can decrease inflammation when it's rubble muscles or if it's taken orally according according to a two thousand eighteen review one hundred thirty. Two original studies published in from taste. Neurology CD can indeed produce information the body and help improve improved pain on the ability in patients with multiple sclerosis. It is anti inflammatory was also interesting is a men's health at attack will bret. Williams investigated the the impact of three different CD products own recovery so he looks at an oil version a role on steak and a topical creed before diving in. He consulted Dr Tattoos Lose Pavlova. Who is an interventional sports and spine specialists who often treats patients using alternative pain management techniques? And he often uses. CBD as is a great way to help muscles recover his experience. He has observed a wide range of benefits including as we said before reduced inflammation stimulated appetite relaxing Lexington soothing muscles and improving see. He does however indicate they're still owns the scientific research to be conducted properly. Validate these claims. So what Bret Williams final now. She started this experiment. Loss of Ma fighting and training so recovery is of importance for him so he found the liquid form of CBD. The the oil didn't necessarily eighties recovery quickly or any more so than any other means. Recovery was all for a few days time. He did feel less groggy in the mornings. which could support the claims of an hard sleep? Obviously thanks to the rolling stick. He found to soothe his muscles. More mmediately than the oil said again. Potentially supporting the claims claims of aiding your recovery topical cream he actually just found to be overly messy so he brought a stick to the stick however this unidentified information shows is that they does show Oh some promise for CBD products actually back up their claims. We're hearing amounted multiple benefits but they're all potentially some side effects and again. Obviously this depends ends on the person it's biological individuality the Horse Studies which reviewed the clinical data an animal studies associate from CD and it safety. And although they found that it's Austin GonNa favorable safety profiles humans that can be side effects with todd style changes appetite or weight on again it really does differ depending depending on the person and it might not affect you but it could so I would say don't try. CB Dave for whatever objective you have to release muscles will help alleviate teens it without consulting your doctor and find out whether it could be right for you but very interesting to see the space develop and see if there's more scientific evidence release to actually show that it is a natural actual method to to eight with depression. Anxiety or soothing muscles are actually aiding asleep as it could be a very useful recovery tool in the

CBD Bret Williams Marijuana Cannabis Dr Perry Solomon MD Dave MA Austin Lexington Todd Medical Officer Founding Member
Dr. James Taylor on Chronic Pain and How CBD Inspired a Transformation in The Waiting Room

The Curious About Cannabis Podcast

10:55 min | 7 months ago

Dr. James Taylor on Chronic Pain and How CBD Inspired a Transformation in The Waiting Room

"Today I'm really excited because I'm joined by doctor. James Taylor from North Carolina in some of my home stomping grounds in the southeast James. Thanks so much for being willing to take the time and speak with me today or Jason. It's modern thank you. Yeah totally okay so just to prime our listeners a bit. Do you mind speaking a little bit about the work that you do. And how it connects to to Hampton CD and all that so are merely a pain physician we have seven pink clinics in North Carolina it was the opioid crisis. Prices that got me involved. Oh in the CBD space About two years ago as premiers coming from medical boards and hospital administrators straighter on We've got to change the way we manage pain CBD came up and opportune time for our medical practice to look figure out what is what do or what is it not do. Offer patients in pain It was very taboo back then in North Carolina to Even even think about this bring it into our a practice So initially when we did that we had a symposium and we brought a lot of people to the symposium we brought the police sheriffs departments attorneys board and members You know anybody we could think of that. Might want to object and so we gave him the opportunity to object if we were going to bring. CD into the State of North Carolina and start using it with the patients No one objected They all agreed were in the middle of an opioid crisis. And we gotta pull out every tool we possibly can use in order to positively affect that So our journey only began their our. We studied some patients and felt good about continuing to recommend this to our patients. And we've just continued to try to understand this this even better of of what it's doing for these folks and how we can positively impact. Their lives in that journey has been a very up and down journey journey. A- and so being new into the cannabis space You just don't realize all the variables that you're going to have to deal with but it seems like we take two steps forward one step back. Three three steps forward four steps back in so that kind of roller coaster. I'm understanding what folks in the canvas world have been up against so the last number of years. Yeah and I've got to say I'm a little surprised that there wasn't much resistance in those early conversations. But that's that's great to hear as well just that there's A desire to try to bring in any safe tools that can be brought in to try to alleviate some of those opioid problems that we're that we're dealing with now and what it What forms of? CBD are being administered in North Carolina. Because I have to admit I'm not super familiar with what's Osman going on there. Recently are people using Like tinctures or edibles different. What types of products are they engaging will primarily tincture In our medical practice we stuck with tincture. We wanted to keep it simple. Yeah you know. Our patients aren't the the most educated and we typically serve the poor and the elderly orderly So we didn't want to bring a large variety of different things so the tincture. We kept it simple. But in the state of North Carolina of of him stores are opening up all over the place that have Food products the smokable him The tinctures bay products The whole Gamut You know the North Carolina and FDA. They have come out a pretty strongly to say. Hey we don't want this food products right but they still sell them. And nobody's out a monitoring regulating them in. Uh we'll see where all that end. Yeah it's it was interesting to me to see Saw Picture very recently of a store in Tennessee that was a CD slash him dispensary and it was set up very similarly to all the cannabis dispensaries. You see you out here on the West Coast or in states that have legalized. But it's all hemp products. That's fascinating to me. That that's spreading across the country and giving people access to canvas products even if it's in that limited CD sense that they wouldn't have access to otherwise. Have there been to your knowledge. Any issues regarding Product safety contaminations or MHM product consistency in that realm. Oil is for the public standpoint. I don't think the public of of see's much of that. I think there's a couple of news articles where some product came in how they came from out West that probably contained. THC mother was not a hemp to rob product worked but there has not been a lot of media attention on Tainted are bad product of now we have a laboratory and we do testing So half my patients take a product that we kind of oversee from growth to extraction the other half of my patients take products they get online So that's very good for me. I'm able to see what these other products are In the new all take sometimes these products from the patient and test them and see what's in them in so we're discovering quite a bit Eh. What's on the label is not necessarily what's in the bottle? Yeah you know tattle on anybody But I think it's a bigger problem than we all realize. Yeah I completely agree just for my own analytical work that I've seen there's Quite a lot of inconsistency batch to batch When manufacturers are making products and then sometimes the differences in product compared to label sometimes that's genuine just product manufacturing variability and sometimes it's militias sometimes? It's just outright companies lying in order to get product somewhere where they it can be sold. Can you speak a little bit to how you know. So you specialize in pain in trying to to help people deal with particularly Egli chronic pain How do patients seem to be reacting and under what kind of dosages yet great question so when we initially brought it into our practice We took one hundred patients in. We studied them at that point. We didn't know that there were different. CANNABINOID profiles we didn't didn't know how to dose it We just did not know a lot. We just put this bottle of CBD in front of a hundred patients And said take a half a dropper twice a day and that should last in thirty days and now come back and tell us what happens and we follow them over about a three month period of time so with not even much knowledge we Able to gain so much insight. Now's a pain physician. We were looking for a pain reduction and of them. Not Needing their opioids And what we found on our initial survey is there. Pain did not affect their pain whatsoever. but what we found or was number one. They slept so much better interesting. He came back other sleep. Went from about four four and a half hours to six hours a night and they started reporting that they were dreaming though so we set. Gosh this is good. You're sleeping better. You're dreaming you're getting more restful sleep deep someone who's got a chronic medical condition. This is very valuable to give you that a rejuvenation of that you need in order to face the next day With your continued chronic condition. The second thing they came to us and told us is that they're anxiety level was less that they were less anxious in. They found that when they were having an anxiety flare instead of reaching for alcohol or Benzodiazepine which we know those plus narcotic will equals death? They were reaching the battle hymn the very quickly they realized if they took other tincture within twenty thirty minutes their prices was starting to dissipate. And so we saw this as risk reduction. Yeah Yeah Yeah exactly. So we can protect our patients out. This is a wonderful reason to continue to pursue those. Yeah and that actually echoes a lot of what I've heard from other physicians and nurses. That have talked to that. Sometimes the therapeutic response you get from canvas product isn't necessarily a direct reduction of the symptoms that you're necessarily targeting but Hits other symptoms that accompany that problem that over time are likely to have a positive effect on the core issue that you're trying to treat as well is it's interesting to hear about People people starting to dream again so that indicates that REMM cycles must be being established for anybody. That's sort of unaware have chronic pain. Wake you up constantly throughout the night and so it's hard for your body. Hit actually sink into the. You know that that depressed and to these rim cycles where you'd really Be Having having you know more lucid dreaming and that sort of more intense dreams And so that super fascinating and there's a lot of debate out there right now about how. CBD Canvas Broadly Affect Sleep is there are mixed voices about that and especially when THC's involves so it's interesting to hear from your perspective and a place that is not dealing with thc that you're seeing positive outcomes with sleep 'cause in areas where they are working with thc it's not what has straightforward. Is that because T- can actually interrupt rim cycles and end. It depends person a person of course to we also so saw that initial observational study. The patients came back instead. They were hopeful and for it. I is perplexed us You know we did. It's a literature. Search found that yes. D- Aachen affects. Serotonin Osso we thought. This was a mild anti depressant effect But over the course of of these last years we realized it's more than that it's neurogenesis it's neuro plasticity. These patients brains. Were starting to grow into win. Your brain starts to develop new luke pathways you all of a sudden have hope you don't patients who are in pain. Chronic pain I think have a form of PTSD you know and they just can't. There's just stock. They don't know life is going to be like this the rest of their life. It's never going to get better kinda stuck in this. RUT IN CD allowed them to have hope in that hope of translated into a lot of positive things in our clinic before our waiting room was it was awful as miserable place to be ENSO's very depressing But all of a sudden replaying reggae music people are talking to each other and sharing. Their experiences really changed our atmosphere of our clinics.

Pain North Carolina CBD Cannabis Hampton Cd James Taylor Jason MHM Ptsd Tennessee West Coast Osman FDA Benzodiazepine
All About Endorphins

20 Minute Fitness

03:47 min | 7 months ago

All About Endorphins

"People have been told in the past. That exercise been said to be an aid. Finale everything from depression. Obesity helps reduce stress helps reduce the risk of cardiovascular diseases. And so on. But what is really going on in our bodies that gives us this empowering feeling so of course helps that it could be due to the fight that we've gone out and progress towards health and fitness goal. Is that sense of pride against all odds more so than that is due to the release of endorphins so in Dolphins on Anura Chemicals. which get their name from? The word indulgence. Which you've heard before which means coming from within the body and morphine? Which is an opiate pain reliever On Dolphins got the name because they are not true pain relievers. They Act has John. Jesus like pain relievers. So dolphins consists of a large group of peptides the produced by the central nervous system and the pressure tree land so since dolphins act on the opiate receptors. Not Brains they reduce pain and boost pleasure. which results in a feeling of well big saw she happens is the endorphins are released. In response to brain chemicals Kohl's neurotransmitters is and the neuron receptors that dolphins bind to are the same ones certain kinds of medicines by two as well and dolphins. Aw as I said the painkillers produced in response to physical discomfort. The improved self esteem that we do feel otherwise known. As runner's high is a result Zolt of these endorphins being released so it wasn't actually until two thousand eight that measuring endorphins in humans was actually possible because we ain't got some new imaging technology becoming available so researchers used positron emission tomography or pet scans to view at brain in both before and after exercise. And after doing this they found the increase in the release of endorphins after exercise. And that's why it's medical medical professionals prescribe regular exercise as a treatment for mild to moderate depression and anxiety because exercise boosts your mood a Walston endorphins. Get all the attention. You'll body also pumps out and the kind of annoyed switch. All a naturally synthesized version of THC. which is the chemical responsible for the feeling that marijuana produces and the most examine that new? Talamante produced in the body is known as Anandamide and this is believed to it. Creates a feeling of calmness. Jim Research is actually found. That's the end of cannabinoid system could be involved in the runner's high because they observed that's endorphins com pass rooted the blood brain barrier whilst the lipid soluble end cannabinoid found at high levels in people's blood off the running so they can travel from the blood into the brain where it can trigger a high. And what's interesting is that Celia Hillard who has HD director of the Neuroscience Research Center. The Medical College of Wisconsin has found that people need eight hours of sleep for optimal ended kind of annoyed production. So this gesture. Although there's no scientific proof a morning homerun is more likely to produce a runner's high than an evening or after noon runs I didn't want endorphins to get all the glory about why we feel so great author director cise. This is of course after we recovered breath back from whatever exercise. It may be a new kind of annoyed. Also have a part in this as well. They're still trying to evaluate wait now which has more of an impact. But hopefully that's given you some science behind wiig sizing can make you feel great. Not only my feeling of pride you've got you've gone out and Don some workouts despite your busy schedule but also because of the neurochemical was ended kind of annoys that are being released as

Director Obesity Anura Chemicals. Depression Medical College Of Wisconsin Morphine Painkillers Celia Hillard Wiig Marijuana DON Jim Research Talamante Anandamide Neuroscience Research Center
Austin to consider stopping arrests, tickets in low-level marijuana cases after hemp law

Todd and Don

01:14 min | 7 months ago

Austin to consider stopping arrests, tickets in low-level marijuana cases after hemp law

"Now also when the law enforcement front well one ordinance authored by city council member Greg Kosor could basically decriminalize low levels of pot possession we have a close up report on that story has written the proposed ordinance aims to ban a P. D. from making arrests of people caught with low levels of marijuana he tweets quote the war on drugs has been a war on every day people and communities of color it's time we change that heather Fazil with Texans were responsible marijuana policy says this comes as public perception of marijuana use grows more positive on both sides of the aisle we've seen millions of people's lives de railed we think people that could benefit from cannabis being deprived access to this medicine it is really wonderful to finally see people having a meaningful conversation about marijuana policy the ordinance also wants to make sure the city doesn't fund or use staffers to develop THC testing protocols or have access to such testing for marijuana possession cases unless it involves the intent to sell distribute or deliver the ordinance has the support of council members Jimmy Flanagan Natasha her medicine mayor pro tem Delia Garza your need to set for debate January twenty third John cooling newsradio

"thc" Discussed on Mental Illness Happy Hour

Mental Illness Happy Hour

01:57 min | 7 months ago

"thc" Discussed on Mental Illness Happy Hour

"And you also don't have to do your sessions via video. You can do them via email. Live text chat phone and then this is where I would normally insert hurt nine other jokes about old timey ways of communicating. We also have a new sponsor for this week and I am excited to introduce their stuff to you guys because I am a fan I'm sure you've heard all about CD and stuff like that when they approach usually about potentially advertising on the shell I said I know that there are CBD products that have thc in their those that don't have any THC and I would only be uncomfortable advertising those that don't have thc in them. Ones used for medicinal purposes. You know be it. Struggles roles with sleep or pain anxiety and I've tried a couple of different brands previously With very it kind of mixed results and they said well. Why don't you try some of our our products before we talk more about this and I decided to try their nighttime Gumy's and I've been using them now for I don't know maybe three weeks or more and they work fucking great? It is so nice having something that I know is going to put me to sleep and not having that anxiety of am I gonNa Fall Asleep at my not gonNa Fall Asleep. So if you're considering checking out CDs stuff Go to early bird. CBD Dot Com it's completely transparent online cbd marketplace and they can help you find the right product what you can check out different products that they have on the website or if.

THC Gumy
"thc" Discussed on The Peter Attia Drive

The Peter Attia Drive

15:42 min | 9 months ago

"thc" Discussed on The Peter Attia Drive

"We have over over four hundred thousand people with medical marijuana cards and of people who were going into cannabis dispensaries two-thirds of them were really there for for medical reasons not to get stone they had learned over the course of their lives that they could reduce their pain often and chronic pain from very serious accidents or operations they could reduce their anxiety and they had learned learned that they could find strains of marijuana and they were using them and smoking them because it was all that they had available to them so so these are people generally who were just looking to live happy normal lives like all the rest of us and that they have found that this is a relatively inexpensive and pretty harmless way to manage what are otherwise very very severe symptoms so that if going back back to your question about utilizing alcohol at the same time there are some people who utilize alcohol regularly in order a two frankly numb the pain even without listening to any Frank Sinatra songs about the heartache and why we're all still in a bar at three o'clock in the morning it's for pain relief for its psychological and sometimes straightforward physical pain relief once people discover that they can achieve that by using a small relatively easy titrate action form people who utilize lines cannabis smoking or vaping are readily able to titrate themselves. which is just remarkable to be able to do that? Certainly certainly I did. When I was smoking cigarettes I could learn how to accelerate my heart rate or relax by just puffing in a different way I gave up that addiction myself interesting? I don't think I appreciated that. You could have that distinction from presumably from the nicotine depending on Yossi either. Are there speed at which you take on that nicotine I could either excite myself to be able to get up for something or you could use it to calm calm down and relax by just simply dosing in a different manner you think there are certain medical conditions that are contra indicated from the use of Thc h see for example the making this. I have no idea that was on with schizophrenia. Or someone with a severe psychiatric illness. Can it be exacerbated by. THC The short answer answer is yes. But that doesn't mean that they should not be available to cannabinoid because again there's over a hundred different cannabinoid specific acidic to the cannabis plant. That could be an has shown to be incredibly useful so yes high dose. THC alone could stimulate somebody. Who has schizophrenia to have an exacerbating of of those things but CB day and maybe even a low level of THC along with it could actually be hugely beneficial back to your question about thc and other drugs teach C.? Plus opiates has shown that a reduction in opiates with a a greater pain relieving efficacy. Without that tacky full access tolerance that we know to be true for opioid use. How much time do you still spend in a hospital setting or an inpatient setting? Do you have any you spend any time there zero anymore. Do you have any sense of how long it will be before. THC END OR CBD make their way into the for example post op surgical patient world which is a synthetic THC has been on the market since the nineteen eighties and we as doctors are allowed to write prescriptions for it across the country impatient can travel with it. That's available now and it's being used I for chemotherapy induced nausea and vomiting in some settings. Not very well because straight up. THC's really uncomfortable does increase. Your heart rate does make your mouth dry does make you feel agitated and uncomfortable. I mean the rest of the constituents within the plant sort of modulate all of that. I'm glad you brought this up because I was going to ask you about the synthetics six. The synthetics have a pretty bad rap. There's sort of the teleological argument of nature always packs the right amount of this antidote versus at Antidote. I mean what what is your take on synthetics through that lens in particular. That's a complicated answer amine. I think what I'm really wanting. Top focus more about is a single molecule doc. You'll as opposed to looking. At many of the molecules within the cannabis plant and try to find utilization no so a single molecule like C.. She Be Day from EPA dialects from GW. Forma came from plant but is isolated and purified to ninety nine point nine nine percent and it required acquired a tremendous amount to get the effect that GW former wanted to get on two types of seizures. We formulate using isolated leded cannabinoid but we join them together along with other constituents so we use less than we capitalize on the synergistic effects of a lot of the molecules. No no differently than what we do in medicine is an anesthesiologist. We just don't push one medication. We push a lot of different medications to lower the the bad effects of of one one particular medicine in capitalize on the good effects of all of them say more about the GW CBD for epilepsy. What is the purity of it? You said it's ninety nine Anna. It's pretty high. It's greater than ninety percent. Tell me about the the success and utilization of that so it's plant arrived but it's isolated so it's purified and they have it for who particular types of seizures. Those kids with these rare sees reforms that are refractory to multiple other traditional form suited goals. I I think they have like a a thirty percent reduction in their seizures but there's side effects I mean there's GI effects. There's liver issues. I mean their side side effects in high high doses of of EPA dialects. What do you think is the potential for CD and sleep? Something that gets talked about a lot. What what is your take on the efficacy of CD oils? Let's start with the oils which are very commercially. Abundant will let me. I mentioned my bias. I took it this morning. Get one o'clock in the morning because as usual. I'm up for an hour trying to do something and it's a little noisy in this city. I needed to go back to sleep so it is in our hands and our experience it works it simply works that is people are are able to take. CBD We think that taking it as an oil is less effective than taking it in a water soluble form but it is certainly effective. We have pharmacovigilance data on several hundred thousand people. The demonstrates straights that they generally go to sleep pretty quickly. Have a great night's sleep and wake up refreshed with no feeling of what other sleep. He bathes. Give of groggy. NECE or anything like that. Most people think it is just fabulous. Do you have any insight into what the mechanism chasm of action is to member multimodal mechanisms of action so anti inflammatory. It also activates. The GABBA receptor decreases his anxiety and a lot of people have that three rolled running around in their head at night and prevents them from going to sleep. So we think it is central activation of Gaba that is would be one of the mediated. There's a a molecule at they're called Fenerbahce which is an oral form of Gabba that crosses the blood brain barrier now. The FDA has not designated at grass so therefore it's no longer available easily but for something that was for so long over the counter. Her it was a kind of a remarkable sleep aid. So one shouldn't underestimate the potency of CNS gabba activation is there any sort of polly. Holly SOM- data that talks about staging of sleep with CBD in other words it's one thing to say great. You know a person can sleep for this many hours uninterrupted. Did you have any sense of the impact of CBD on sleep architecture. I haven't seen any data like that in your questions are remarkably remarkably doubly perceptive have to realize that at this current time because of the still illegality of THC and the confused legality about all of the others that pretty much every university specially medical universities do not allow research to be done on the facility unless someone has a DA license and even then getting the DA licenses all long drawn out process so that very little work is able to be done and there are thousands of medical researchers. Who would love to work on these problems albums? But they can't just like they haven't been able to for fifty years but is CBD not permitted for research if the THC level is low enough. That's that's only come about in the last few months so it certainly takes a lot longer for research protocols to be Developed to move through. Nih to move through whatever funding opportunity. There is and I expect that in the next year ear or two or three that they'll be much more research done on that. It's still a highly restricted highly restrained. And frankly frankly the university administration in almost all of these schools and universities are very very worried about jeopardizing their federal will funding for billions of dollars of other projects. In other words. It's not that there's a dearth of funding if a philanthropist came along and said to somebody at the University Yeah Michigan in Ann Arbor. Hey here's five million dollars I want you to study the effect of CBD on sleep duration and architecture. The university city would say well thank you for that but I don't want to jeopardize the billion dollars of NIH funding. I have is that. Am I understanding you correctly. Yeah well I wouldn't pick on U. OF M. because my wife works in pathology apology there. So but it's a great school terrific school. Football's coming back folks that any university in these stages will move move much more carefully to consider what the research is. And who is the researcher simply because of fifty sixty fifty years of illegality as just so surprising to see how far behind. THC NCB DR when you have a beautiful roadmap from organizations nations that have been funding so much psychedelic research when you look at maps. The Multidisciplinary Association for Psychedelic Studies started by Rick. Dobelin I mean started this organization. Nineteen eighty six thirty three years later they are now in phase three studies using MD AMA which is as you know obviously schedule one. I'm kind of amazed. Is there not a comparable group that is advocating for the judicious study of THC in CBD. We Dr we run clinical trials regularly. Dr Kim Lewis here is running clinical trials right now and there are others but they're from. Let's call it private sources. So is that the business model of your company is that you have a product that you sell and the proceeds of that help fund the research. The yeah that's pretty much it. We came up with formulations that we felt would work and then we ran pilot clinical trials to see see how they would do in a small patient population and once we saw that that was getting very good response among people then when we were able to distribute the products within the state because we are state licensed to be able to do that and now we are taking the funds from essentially from. I'm back cash flow and scaling up to be able to do studies under FDA office auspices which are frankly much more expensive to do because because of all the controls that go along with it. Talk to me about this idea that we alluded to twice already. which is the water? Soluble Ization of something. That I didn't assume could be water. Soluble is D- we have a number of patents on it and a number of them were moving through so you'll have to forgive me force speaking generically generically about that. We have one issued patent out of the seven that we filed for and that was to figure out we figured I had a freeze dried right cannabis and that's an industrial process and it helps so. That's an awarded patent and anyone can look that one up. THC AND CBD and all of the molecules that are in cannabis that appear to be useful and viable or all oil soluble people. They are not. They are not water soluble. So that if you put him in a glass of water and start you'll have little oil globules on it so we you figured out how to be able to convert that instantly into a water soluble molecule. So that when a person puts a drop of this or a powder this on their tongue. It doesn't taste oily. It doesn't didn't feel oily in it doesn't act like an oil and is everyone knows. Yeah you can have some oil and vinegar may be on your salad. But the body doesn't doesn't really like to have a lot of oil in it on a regular basis whereas everybody can drink pints and pints of water gallons of water perhaps a day so these molecules are rendered to be water soluble and because they're put into very very fast rapid dissolving tablets that disintegrate in about fifteen seconds or so do they disintegrate under the tongue and therefore escape the first pass effect of the liver or are exactly right under Tong on top of the tongue wished around the tongue that they're not to be swallowed they're not to be swallowed they're called sub lingual because it's under the tongue but what happens is is as the tablet disintegrates literally in the mouth the molecules move towards the tissues of the mouth tongue gene or throughout the oral cavity. What we see is in about a minute? The molecules have moved into ooh the bloodstream. And for those who are sensitive enough they can actually feel their toes tingle in two minutes which teaches us that we have full foale systemic absorption the frankly the molecules of reached persons tolls and. Then we find following that that people are able oh to experience whatever affect medical effect that we are looking for in about eight to ten minutes. So that's the onset of sleep for sleep formulations the.

cannabis schizophrenia THC EPA Nih nicotine FDA marijuana Frank Sinatra Yossi Multidisciplinary Association Dr Kim Lewis DA Ann Arbor University Yeah Michigan liver Tong Holly SOM
"thc" Discussed on The Peter Attia Drive

The Peter Attia Drive

14:56 min | 9 months ago

"thc" Discussed on The Peter Attia Drive

"I'm glad you brought that. Add Up. Tell us a little bit more about the difference between hemp and cannabis specifically and again using the CD THC delineation so the legal definition is for hemp CULTIVAR is to have less than zero point three percent by weight of the actually compared to the rest of the biomass your mass or the rest of the molecules in in the plant. Technically that would make anything hemp. That doesn't have. THC In it right exactly. So people use cannabis plants. It's in just cross-breed so that teach see is less than point three percent so that they can grow it but you know the term of industrial hemp emp back in the day when our Constitution was written and sales. Were you know being made out of hemp. It's totally different plant as it is today just because of of crossbreeding in and forming the way. WE'RE DOING IT Steve. The farm bill brought this to the forefront recently. Tell us about the farm bill and why that's relevant. I WANNA come back to this but just well. We're on the topic of hemp. It's important I think for people to understand this distinction. The congress decided pushed forward by several legislators who had large numbers of farmers that this would be a really good cash crop for them. When you think of these products are selling Ling for thousands of dollars pound compared to fifty cents or a dollar a pound for lettuce or tomatoes? So if you're a former you'd much rather grow something something that you can get. Thousands of dollars for the idea was put forward that this should be something that's allowed now. We can see across across America. That people really are interested in it. That medicine can be developed from it so it was with this idea that a number of legislators laters particularly Senator McConnell had a number of farmers in his jurisdiction wanted to be able to help them in their businesses and in their in their personal lives to be able to develop this otherwise. These products are imported from overseas. And we'd we'd like the American population to be able to have a good well regulated source of product here. I think that was the entire idea behind. It was that we would bring the the. US Department of Agriculture as well as other scientific bodies like FDA to be able to begin to study these products. And help the growers. All of the growers that have worked on cannabis hemp products have had to do this for generations without having someone like the. USDA custody a around to tell them what pesticides were appropriate to use headed. Grow at how to have good growing conditions for it so this has really helped. Don't think to be able to advance. It bill basically just an economic package that made it more attractive or was there some legalization allegation that was previously. Not there. The farm bill really provided legal cover for farmers to be able to grow the him and then to be able for processors than to be able to process it into oil and be able to turn it on into two other products so it started out as something to just eight farmers but now it is moving through the economic distribution chain. And that's why we can see it now in nearly every drug store or big box store as finished goods on the shelf. What are some of the products that come from the implant there are vape cartridges? Certainly although there at the moment not all that perhaps professionally Stanley done except by those who are licensed to be able to do it. There's a very large grey or black market in it but there are lotions creams ointments joint moments. You can find. CBD products in Ice Cream and tea. Soon it'll be in coffee. The and nearly every other consumer product that's available is the idea that there are certain hemp products that do not contain. CBD In certain hemp products that do or is the implication that all Products are containing CD. So I think what you're asking is about industrial uses of hemp beyond the collaborate. And so you can with that flower into seed and make hemp seeds from it which has a wonderful profile of mega mega six. Probably better than anything and wonderful source SUV. Protein is well the fiber that it comes from him. Fire has it tensile strength of steel or greater than steel where you see plastic goods. You can actually substitute for him. It just really expensive machinery for now until vigors out in displaces the petroleum in plastic. Or what is it displacing yes it displaces. Patrolling the plastic. So you can make a credit card. At of hemp fiber you can make hemp Crete so instead of concrete you can actually use it make it eight to make concrete you can their. BMW's right now that are using parts of their their door panels and dashboards using hemp. You can make cloth off. You can make clothing. You could make sailor's sailor has a sense of you. Take all of the biomass. That's being produced in the United States from hemp crop. Today how much of it it is being used for all of these industrial uses and how much is being used just for CBD. I assume the latter is a tiny fraction of it. I think I think. CBD He is the Lion Share of it. Because that's where the money is right now. You know the De cort occasion machine. The machine that is required to break down the stock which is incredibly fibers. Burson tough is very expensive right now. But and I think that you know there's such a huge interest at least in the united everywhere especially in the United States for CBD as a potential medicine or tonic. That's where the money is. So it's a lot easier to extract and make derivative products than it is to create a lot of these other iterations that I just described as an industrial use. But let me just interject. Some of these other uses are just remarkable and have been around for a long time Henry. Ford personally was very proud of having developed a hint mobile and he actually built had built a car that ran and it's fuel was fueled by simple so the entire car in the nineteen thirties. These could have been put out on the road and they had to shelve that project because suddenly hemp illegal because it was came from the marijuana sought marijuana plants when did CBD become federally legal. Assume it is federally legal today or is it still state regulated. Well it certainly is. State regulated in each state has its own regulations. The federal regulation of it is continuing doing to unfold. The farm bill has legalized Hem itself. It has not directly Said said that. CBD IS OKAY to put into products rather there's been an intense push on the food and Drug Administration whose responsibility it is to regulate those kind of consumer products that they should move expeditiously and actually deb testified before FDA about five months or so ago on the safety and effectiveness of CBD. He d to help them in their data gathering to win you spoke to the FDA. deb What were the main points you tried to get across in named points that we discussed was was about a clinical trial that we ran using water soluble iteration of CBD. For mild to moderate pain in a sixteen patient patient cohort and the result of it and I wanted to share that with safety efficacy in our results. Let's talk a little bit about that. Sixteen patients that had mild to moderate pain. Meaning what What was the ideology of their pain? So multifactorial I didn't just stratified to one condition. 'CAUSE 'cause I just wanted to see was a proof of concept trial and I actually didn't think it was going to work. Steve was kind enough to let me formulate an ultra low dose five milligrams of CBD abd with some curiosity turbines. In order sizable tablet. I gave it to sixteen patients who were had mild to moderate pain for which they were treating their opean with an over the counter medication and we ran this trial for two weeks and we had statistically significant can't decrease in pain across all sixteen patients. How do you control for the placebo effect? There was there a control in that study. There was nine I again. It was a proof of concept. Study to see if this ultra low dose of CBD would even work and it did. There's no control for Placebo for for really for or anything I mean I know lots of patients. Sure you do as well that seemed to really respond to a whole host of medicines whether it comes from a double blind randomized trial or not how does CBD in your mind differ from THC. We know obviously how it does intoxication standpoint. How do you think it differs is in the remainder of the profile works in different mechanisms of action? You know so for example CD doesn't sit on a CB one interceptor but would he does. Is it interacts with the breakdown. Product of are naturally occurring Indo collaborates which does sit on a C.. VP winners after so by enhancing. That that's one pain relieving mechanism of action in O would interfere in interacts with dopamine gene. Norepinephrine epinephrine type receptors and enhances those chemicals as well so it works in a multi modal way just like all of our are the medications. I'm trying to in my mind. Wrap this idea around ven diagram. THC IN CBD. Where does that make sense where you have certain things is that they both do and then things that are unique to each of them? Does that make sense to think of it that way it. It doesn't it doesn't so I understand as allopathic physician position that that's how we like to look at things that's a very reductionist view of it and I think it is really botanical medicine. We really we have a lot of different constituents within it. There's over a hundred different cabinets over eighty plus turbines flavonoids and probably constituents were not not smart enough yet to even have figured out. What are the terrapins? Do turpin occur in nature in all kinds of plants and foods that are you're giving the taste and the sent to all kinds of things and they're anti-inflammatory they're actually secondary metabolites like the canal as well and it's used for the plant not for our benefit for for its benefit as in natural pesticide. A antioxidant and it works that way in our our bodies as well I WANNA come back to sort of the. THC side of the equation. Let's start talking about some of the health risks and benefits and let's start start with the risks. What do you think are the most important risks to understand from? THC Use so think everybody is different. We're all an N.. And one and we all respond differently to the same type of thing so if I give one person that aspirin their headache go away. Somebody else may die of You you know an allergic reaction to it in some people who are very sensitive to teach see. They may not just feel intoxicated but they may feel so so much anxiety and panic that they are incredibly uncomfortable and some is dose dependent with some experienced that even with a small amount some people people experience a feeling of well-being with a little bit of the some people have a rapid heartbeat and their blood pressure shoots up and have an uncomfortable experience. That's how much of that do. We think is setting dependent so if you took the same person administered the exact same does by the same route but under different settings things either the actual physical setting in or the emotional state there in. How much can that impact the response? I think anytime you're dealing with something that plays around with narrow chemistry set and setting is always a huge important thing. Same thing with alcohol. I think there's one part of this while we're talking about this safety or potential adverse events from this that we should also address in my experience. This has the lowest toxicity potential chill of any pharmaceutic nearly of almost any product. I've ever seen that is in the course of history. We really do not have any any deaths or truly serious events that are attributed to THC or CBD at all all it is so less toxic than what are common over the Counter Drugs Aspirin tylenol etc and certainly certainly foreign away compared to alcohol which is truly toxic. What is the reported L. D. Fifty of THC? So there really league isn't an you cannot may those lane to people what L E v L D fifty is the lethal doth that it takes in order to kill off fifty percent of a population usually in mice or rats with THC and CBD and all of these cannabinoid. It has never been possible to dose them with enough to be able to do it so that there is just as a simple cut off. Generally that it's something more than five grams per kilogram. So that's a tremendous tremendous absolutely tremendous amount of cannabis to be able to take on in the seventies an attorney for the. Da Actually was writing in support of de Scheduling Cannabis. said that the lethal dose fifty would take seventy five kilogram man to smoke fifteen fifteen hundred pounds of cannabis flower in fifteen.

CBD cannabis US Department of Agriculture United States Steve FDA Aspirin BMW America Senator McConnell Ling congress food and Drug Administration Stanley Burson mechanism of action Ford Henry epinephrine
"thc" Discussed on The Peter Attia Drive

The Peter Attia Drive

16:20 min | 9 months ago

"thc" Discussed on The Peter Attia Drive

"And Deborah Qimlas Deborah Steve Thank you so much for making time to come in to talk about this stuff today. This is kind of an unusual podcast in that. We aren't introduced through anybody. I sort of organically reached out to you guys on the basis of so much demand in so many questions about this topic. which is something you know as I've alluded to I'm completely ignorant of so? This is a topic I've been really looking forward to learning about because patients asked me about it constantly gently I think the implications are only becoming more significant as we watched the evolution of legal environment. So having a physician and a lawyer talk about this is perfect deb. Can you give me a bit of background on your interest in this. You're an anesthesiologist. And now you specialize in pain. Tell me what drew you to this specifically so what drew me this to this is that my mom was dying from a complication from former student goal drug and because of that I started really thinking talking about what we learned in medical school however trained and what else could there have been from my mom as an option of pharmaceutical and the as she lay dying my significant others in Israeli said you know their study medical cannabis in Israel and unfortunately my mom didn't have an opportunity Fortuna try medical cannabis as a pain reliever because she died but I spent really since two thousand thirteen until now studying and investigating veracity. The city of whether or not cannabis truly is a medicinal molecules. Steve How did you guys meet and how did you get involved in this well. I've been involved in pharmaceutical formulations as a scientist for almost fifty years now as a forensic toxicologist at New York medical examiner I worked on eighteen thousand autopsies so I developed and formulated the drug Liquid Drug Methadone about forty seven years ago because friends zip mind coming back from the Vietnam War. So that worked out pretty well develop that formulation. Methadone is done very well of helping people around the world and I went onto become FDA attorney working in the pharmaceutical industry but always working in this arena. I became interested in cannabis as a medicine almost forty five years ago. A friend of mine came back from Vietnam War with PTSD and he asked me to develop a drug that would help cure him of that and I noticed that when he smoked marijuana he felt much better when he drank rancor got pills from the. Va did not. And so I realized cannabis could be a medicine but it just wasn't legal at the time and I wasn't that right kind lawyer to get. That legalized now. I have that opportunity to be able to do it. That's what brought me into it. He also mind buddy who's passed away of cirrhosis psoriasis. Of the liver about seven years ago made me vow to do this. So developing Methadone at the beginning of my career was a first this book and and now developing all these formulations to help people with cannabis is the second book and on my career. And how did the two of you me a I lecture around the country and around the world and I present studies that I have done on my own. These case studies I treat over four hundred. The patients free of charge a bad business model. But what I've learned from these patients is tremendous using diet changing cabinet medicines and I share them with colleagues colleagues so that they can understand. Cannabis's medicine and Steven. I met two years ago at in Cologne Germany. I think it was at ICM. The M where I was presenting a poster in he tracked me down and we had our first conversation there and together you guys are part of a company will probably hear a little a bit about that company today but the the aim of this company I assume as to create sort of what you perceive to be the safest most efficacious form of delivery of cannabis is that a fair assessment. Yes that's exactly. I think to understand why you guys do what you do. We have to understand a whole bunch of the things that I don't understand right now. So let's just start with some history. How long his cannabis been consumed by humans to the best of our knowledge? Historically it's been used as a medicine over five thousand years I mean this is crazy. It's new for us now. But it's not a new medication in Asia. The the king fancied himself a pharmacist was treating people for all sorts of disorders from gout. Too Absent Memory. Believe it or not even though people or like dude. Where's My car here? He was helping people with memory loss with no the ancient Greeks used it topically on their horses. Which is why I I do know that? The acid forms of the cannabis medicine actually work because they love their warhorses. They applied the cannabis cannabis leaves to the worst bodies to reduce the swelling inflammation and infection after a war or battle historically wended ended it sort of fall out of favour back in favor of sediment for most people when they think about marijuana they sort of think of the sixties and seventies as this era in which h the public sort of got to know it and it became then sort of demonize. When was actually scheduled? Steve I think that was the beginning of around nineteen thirty you were so that is there. Were a number of individuals who thought that this was just completely inappropriate. Drug drug to be allowed out of recreational drug and there was a lot of movement towards controlling people's appetites in many ways including including drinking alcohol that have floated in and out through America and across the world so it began then with an idea of prohibition and it was really given much more emphatic push under the Nixon administration for. It's often often said for their own political purposes of being able to disenfranchise people who would utilize marijuana young people or the people of Color and that became essentially the war on drugs policy. That was promulgated through the United Nations around the world because the United States often was the funder of those activities. That's continued for quite some time but is now as everyone knows dramatically addict dramatically changing now unlike the sort of psychedelics which were actually scheduled only about fifty years ago. You're saying marijuana was scheduled in the thirties. Ladies I mean this is before the FDA well FDA has been around for at least that long and the originally scheduling of this was under D. EA as a narcotic drug and therefore it would not be allowed and da really had much more of a law enforcement orientation mutation while FDA does have a staff of essentially policeman working with them. They're not organized in that manner. So they're much more organized towards what what is a medicine. What's a food and how to be able to keep our American health policies? The best possible for people you talked a moment ago deb about topically applying this. How did people do that? was that an oil. And what was it. I mean not that you were there at the time we could go back and figure it out to the best of our understanding. What what is it that was being applied to for example a horse or how was it being used medicinally five thousand years ago it varied depending upon the indication and what they wanted to do but the worst example hampel was they were actually applying leaves to these horses? The actual you know families irregular leaves there are small amounts of tricalm's tricalm's on those leaves with Cavanaugh in them so it of course it would work which really interesting in India they would mix it with heat and milk and make something called hung b. h. a. n. g. and they would drink it as an anesthetic for people so oh it really did very it was very interesting that people apply these things in different ways so today when people think about marijuana the thing thing they probably have in the back of their mind is more related to the properties of THC. Is that correct. Yeah I think that most people when they think of cannabis think about it as THC H C intoxication and smoking. So let's talk a little bit about that so you use the funny reference to dude. Where's my car? So Jeff Speeco League falling out of the van big plume of smoke coming out after him. He is taking a leaf. He is smoking that leaf. MORALIZE charlize with broken pieces of it rolled up into a joint and being smoked right so cannabis is a plant is very interesting right. So when he grows in nature it grows as a flower the leaf life does have some cannabinoid in it or some of those medicines in it but really the the most bang for your buck. It comes from the flower where that's what it is. So spur call he. He's probably buying off the street and maybe getting some leaf but he's hoping for some flour because that's where the majority of the medicine is and you know drying it out and rolling it up and combusting it. The interesting thing is you can eat the cannabis plant all day long. You may get a belly ache from all the the fiber but you won't get that intoxicating doc skating feeling because it's chemical constituents are not in a way that can get you intoxicated. I see okay. So let's talk about how that intoxication oxidation works. What is THC stand for tetrahydrocannabinol? And what does it do. In the brain. So our brains have these sort of docking stations nations called receptors and chemicals act on different docking stations or receptors. In order to effect a change so teach see works works on these docking stations in our brain in our peripheral nervous system known as CB one receptor can advocate. One receptor wasn't very interesting name for it. But that's what they call it and they're also canaveral to receptors or C. B. Two receptors were frowned powerfully predominantly on immune cells but also in other tissues. Well and in other organs and and to teach see has this really unique ability to activate or sit on these CB ONE NCB to receptors in. Did you say both to be one and two are peripheral they can be. CB Two predominantly prefer all CB one is predominantly Anna brain other nerve so the peripheral nervous system and what is the next chain of events so once thc binds to these receptors. What happens inside the cells? Oh Gosh so. Depending upon wearing in those receptors are located will determine what happens so for example. If it's in the hippocampus it may stimulate aries the reason that area that will help you extinguish memory so for people with PTSD who cannot stop thinking about certain things that area area of the brain extinguishes memory and help somebody with PTSD maybe to get some sleep. How do you think it acts with respect to pain? It's a multi multi-modal different way of doing it so centrally it does interfere with Perria. Aqueduct Grey areas these areas of of the brain that conduct pain signalling signaling where a brain actually understands also works for fully on immune cells to decrease inflammation and reduce side a kind expression so it works in a whole host of different ways. We're used to thinking in medicine actually as now a path of a single molecule single target. But what you really learn is that that's a great way of understanding how a drug could work. But that's not how it works in in a biologic system known as a person or so contrasting this with what you talked about with respect to your mom's care for example she was probably being prescribed. Opiates I'm assuming sue my mom actually died. From fracturing into death from pharmaceutical known as phosphate from Fosamax. The weird thing about my mom said she was one of the twenty to thirty percent of people who when they took opiates Viet had an enhanced response to pay not a decreased response to pain so basically she was using Sienna thin non steroidal to try to reduce their pain which when she spontaneously blew out her pelvis. You know didn't really help that much. So we were just hoping that since medical medical cannabis works in different methods for pain relief. It could have been an option for her with curator but helped her now. One of the other effects of inhaling marijuana for many people seems to be an increase in appetite. Do we have a sense of why that's the case. And that's I remember certainly in medical school. That was even something we talked about. A lot was patients that had wasting syndromes either with cancer or AIDS. This would be a great way to help them eat exactly so there are areas of the brain that control appetite tight and nausea and vomiting as well in the area in the middle in those areas is replete with CB one receptors so when those areas were stimulated. Did your appetite is stimulated and you actually have a desire to eat which you're right is life saving for somebody who has wasting syndrome or or who has chemotherapy. Induced nausea and vomiting. There's this other thing that now people talk about a lot called CBD. I probably hadn't even heard of until maybe four or five five years ago. I mean Steve. How long has cbd been understood as a distinct part of this equation so this is a truly revolutionary Inari new molecule to come out into the public consciousness so quickly it's always been in the plant and and available to us but it's because people were so entranced with the idea of let's get stoned or then let's do some science science on this stoning aspect of THC that that drew most of the attention? It's just really in. The last is two or three years that C B because of its non hallucinogenic effects has become interesting to people because it appears to have it does have so many medicinal applications and at the same time doesn't get a person stone. How is that possible? What is it doing chemically to create that distinction so different than THC CBD does not sit directly on CB one receptors or C. B. Two receptors but works either indirectly activating the endo collaborate system or it works on completely different receptors? And so together it has a synergistic effect with THC. The other molecules leaving the cannabis plant or by itself is pretty effective as a medicine now in nature. Do they come lockstep one and one for every molecule of THC is one CD coming with it. Or how does that work so in nature it doesn't existed all right isn't until you apply time and temperature and get rid of that acid form that Corban Group on either. THC OR CBD or any of the other cannabinoid so that's kind of interesting there's a baseline anyway but cbd there are cultivars or plant strains is known in the street King Engro in higher concentrations in certain cultivars it can occur as a one to one one molecule to molecule. It depends upon the strain that you're growing phil legal legal definition of hemp is something that's hiring. CBD A and less than point three percent TJ..

cannabis marijuana medical cannabis Deborah Steve FDA Methadone PTSD THC Va Israel cirrhosis Deborah Qimlas Germany CBD United Nations nausea
"thc" Discussed on Stuff To Blow Your Mind

Stuff To Blow Your Mind

03:50 min | 1 year ago

"thc" Discussed on Stuff To Blow Your Mind

"That of the roster far, I movement, certainly, you know. Jamaican music the dub reggae. They're huge huge influence of cannabis. Yeah. It was art for and I think like through most of present day western pop culture that is like a stereotype. Yeah. Yeah. But but certainly the rest affair movement is real. It's a Jamaican Abrahamic faith that rose in the nineteen thirties following be coronation of highly Selassie, the first is emperor of Ethiopia. And they they thrive to this day. They recognize the Salafi as the messiah, and they regard cannabis is a spiritual act and metaphor for the burning Bush of the old Old Testament. And in by the way, cannabis would have spread to the Caribbean during the nineteenth century of via Indian laborers brought in by the British. Okay. Okay. So, but this is an interesting modern example, where we see cannabis as a as part of a religion as a religious. Right here in the states. You have you also have various movements of I think varying levels of seriousness. Yes. Such as the Christian THC minute ministry, the cannabis assembly that church of cognitive therapy, of course, temple for twenty. The list goes goes on and on. But but throughout human history, you do see cannabis playing a role to varying degrees. You know, maybe not as extreme as Ross defy. But you see it playing varying degrees in religious, right? Yeah. That certainly makes sense given it's a biochemical properties in this thoroughly connects right back to two of our more recent episodes, the cargo cults episode and the, hyper real religions episode. Oh, yeah. Yeah. Totally. And again, we could we could spend a whole series of episodes just all the various different cultural examples now when we get to the United States in our modern times, we pretty much have to mention Reefer madness. Because this was a if you're not familiar with. This was this game on the nineteen thirties. And it was an exploitation propaganda film about how marijuana turns young people into just raving maniacs. Like joker faced maniacal crazy. People or just like complete, you know, gutter crawling junkies. Yeah. And it's funny. I mean, like the thirties twenty years before the nineteen fifties. When the same thing was going on with comic books. Right. It's. Real tradition in the last century of American life of finding a thing and blaming it for juvenile delinquents or hyperactivity or behaviors that we don't find that fits to the conformity of of quote, unquote, traditional America. Right. Right. And in this case to helping to bring about moral panic. Yeah. Surrounding the thing, which of course, ties back into our episode on satanic panicking. But essentially you had US laws against marijuana and other drugs drugs popping up in the nineteen twenties though, marijuana laws at the time. They didn't differentiate between hip and psychoactive cannabis. Right. And this is apparently due in large part to the influence of the cotton industry because they didn't want the. The district to come in and take away the biz. Yeah. Because it's like significantly cheaper, isn't it? Yeah. That's my understanding out. And then so so you have the Federal Bureau of narcotic narcotics under Harry, j and Slinger and he waged war on marijuana just throughout the thirties. He rejected clinical analysis that even at the time concluded marijuana did not induce violent behavior or lead to the use of more heavily addictive drugs. Instead, he waged this campaign of yellow journalism and propaganda tied in the evils of jazz..

cannabis marijuana Harry Caribbean Ethiopia United States Selassie Ross Federal Bureau of America Bush Slinger twenty years
"thc" Discussed on KTTH 770AM

KTTH 770AM

01:57 min | 1 year ago

"thc" Discussed on KTTH 770AM

"THC brought to you by leafless in Seattle, rain gutter guards. Release of the mullahs report coming soon, I'm Carmen Roberts. Fox News attorney general William bar gives lawmakers a timeline for when he will turn over the special counsel report on the Russia investigation bars appearance at a house appropriations subcommittee was scheduled to be about his budget requests. But it was hard to avoid is one democrat called it. The elephant in the room. Let me tell you what I'm getting at that. I find quite extraordinary New York Democrat Nita Lowy press bar and how he was able to so quickly issue special counsel Robert Muller's conclusions. Farces his office was updated throughout the investigation in that context. There had been discussion. So there was some inkling as to some of the thinking of the special counsel bar expects to make red acted version of the Muller report public within a week Jared Halpern on Capitol Hill this as bar has assembled a team to look into the origins of the FBI's counterintelligence investigation into the Trump campaign. Pain. An administration official tells Fox News. There's also a separate ongoing investigation. By the department of Justice inspector general into the process used to obtain FIS awards to eavesdrop on certain people associated with the Trump campaign hostility on Capitol Hill is Treasury Secretary. Steve Mnuchin testifies before the House Financial Services committee and chairwoman Maxine Waters. I've told you as I thought it was respectful that you'd let me leave at five fifteen. Any time. You make all ties you want. Please dismiss everybody. I believe you're supposed to take the gravel and bang it. That's least not instruct me as to how to conduct this committee. Democrats wanted to know of treasury would release the president's tax returns Mnuchin said the treasury's legal department had informal conversations about it prior to the congressional request. But he was not involved, and therefore he could not.

special counsel William bar Steve Mnuchin Robert Muller treasury Maxine Waters Carmen Roberts Fox News Seattle department of Justice Nita Lowy Jared Halpern Russia New York FBI attorney
"thc" Discussed on Fresh Air

Fresh Air

02:16 min | 1 year ago

"thc" Discussed on Fresh Air

"So when we smoke marijuana, the whole brain is flooded with THC, and that causes the cell to cell to communication in cells throughout the brain to be enhanced or to be exaggerated, and that's really fun because it seems like while everything is so interesting. Everything is beautiful the music is so rich the colors are so wonderful. The food is delicious everything at once is turned on. That's not how the natural system would work would work sort of with discretion. But anyway, so all over the brain it's enhanced, and that makes everything seem richer and more interesting. What's unfortunate is the brain does adapt to that and adapts by decreasing the number of sites that THC can have an effect. So those sites down regulate meaning they go away over time. And it doesn't take long but regular. Her use the more you use the more often you use the less of those receptors. There will be or those sites for THC to act there will be and that means that when you have THC things aren't quite that great. They used to be wonderful. And now, they're just pretty good. But when you take away the drug, then things seem sort of lifeless and gray, and maybe less interesting. Oh, you are you describing the form of addiction. I think so. So there is addiction to THC in. We know that it stimulates dopamine in the in that pleasure or news pathway, and that's really the definition of whether or not a drug is addictive. It does so more in some people than another. But of course, those are the ones that are at risk for addiction. It also causes tolerance. Like, I'm describing. So if you smoke regularly, then there are fewer sites for the THC to act, and therefore you need more to try to produce the same effect, which eventually he won't be able to do. So you're dependent also because when you take the drug away things are not as good as normal. My guest is Judith griselle neuroscientist and author of the new book never enough the neuroscience and experience addiction after we take a short break..

marijuana Judith griselle dopamine
"thc" Discussed on This Unmillennial Life

This Unmillennial Life

04:39 min | 1 year ago

"thc" Discussed on This Unmillennial Life

"And I think that that's a really important point to underscore for people as they're listening to this, especially if you're listening to this and you have preconceived notions about medical marijuana in preconceived notions about well, whatever treatment if it brings along with it this high that's not for me. It's not for my aging. Parents it's not something interested in. That's a real distinction that I don't want people to lose sight of. Absolutely. And that's something that I learned in this process of my training. I did training at the holistic cannabis academy. And it's an online school with over thirty modules by speakers from around the world who are experts in this field. And that was one very first takeaway that I got from this training. I said, wow, you know, the CBD and all these herpes and all these other things now in saying that there are some medical marijuana patients who need a little bit of THC G H. Is better for some things. For example. I have a client with Cleo blast Oma the receptors for THC or found in the brain. So she needs a little bit of THE because that's where she wants the effect in her brain to quell to keep those tumors at bay. So there are some people in THC is all bad. And here's the good news. If you have a condition that requires some THC, for example, with some chemotherapy side effects, the decrease in appetite teach a little bit better than CBD in increasing someone's appetite, but if you give someone THC, and you also give them CBD it tamped down the psycho activity. You do to parts of CBD to one part of THC gets a whole different ballgame. You don't get that high. That is so amazing. And that's exactly the information that Janice shared with me when I. When I first started hearing about this. I thought this is the part of the story that's really lost. I mean, we're not going to dive deep in this episode into the politics behind medical marijuana or recreational marijuana. But I do think that you know, it's a story that's talked about a lot right now. But not this part of it in. That's the part. That's so fascinating to me. Now, you mentioned, you know, a a client patient that you have right now on a particular condition that she has. But can you talk about some other conditions that cannabis in CBD, and maybe even some teach see are used to treat some of the clients that I've seen have come to me with insomnia. That's a problem. Fifty to seventy percent of people report that they have some issues with insomnia in a lot of women that I speak with really severe issues with insomnia. So that's one thing that's cannabis can help with one condition and Sidoti. For sure I have a client that came to me and said, you know, I'd rather not go on anti anxiety. Medication? So I'd like to try CBD to see if I can keep it at bay and get through this period of my life and not go on pharmaceuticals pains is a big one but fibromyalgia rheumatoid arthritis because of the anti inflammatory properties. I have a brother-in-law who's got pretty bad arthritis in his hand. And I gave him a solve. So I sourced some CBD's hemp derived CBD products that are organically grown and their high in all the terp Peens and CBD with zero THC. So I gave him some of this up to rump rub on his hand. And he said, it's amazing that the pain and the inflammation. He's able to move his hands better. So that's one way that you can use the people, I think. I tend to think oh you have to smoke if you right, right? And correct. Not really none of my patients are smoking joints. They're using soph-. There are tinctures I have a tank shirts. Peppermint, tincture you put half a dropper full under your tongue and keep it in there for sixty seconds. And it's absorbed through your membranes and your mouth, and that provides relief there gel caps that have CBD. It's highly bioavailable and all the myriad of Turpin other cannabinoid, so smoking some people might want to vape, which is a lot less harmful for you than smoking..

CBD marijuana insomnia cannabis holistic cannabis academy Turpin Janice Sidoti seventy percent sixty seconds
"thc" Discussed on Biz Talk Radio

Biz Talk Radio

04:36 min | 1 year ago

"thc" Discussed on Biz Talk Radio

"So from without the CD, and when somebody's nervous system is constantly firing. It's like their body is making rust all day long. And when you put the CD, and it just like takes that out of the factor. It takes out of the mix, and we always have to say, yes, it makes tremendous sense. And we always have to share with people that that means that you don't get high. There's no THC, and that's our biggest. Educational piece on this program is is to distinguish but there are so many benefits. And so if you can talk a little bit about. Why you love the CBD, and the fact that you will never get high. So we could we could both write consume gallons and gallons of oil. Hemp oil full spectrum CBD oil and never ever get high. Right. There's no there's no psychedelic type of effects like that TVD the way I describe it to my patients to my friends, and is you might feel in a way as if you had a glass of wine or a few just finished a yoga class. You just have that like. And your body, but your brain is more, sharp and focused and clear, then you can imagine without because when you take that stress and all that monkey mind or mind chatter out of the way are all your to do list all day long. You just clear, and that's really how cvt makes you feel and the CBD that I use is more of a super food, and it's considered a vitamin sold like a vitamin and the regulations with that do not allow for THC to be in there. I can't speak to what maybe at some of the dispensaries around the country, and that are growing and popping up. They don't believe they have the same regulations. But when you purchase the as a vitamin at a SuperFood. You are definitely not getting THC in there. There are compound. There are products that do specifically say there. And CBD. But those are usually really labeled clearly, and there are some people that like the benefits of having both. But for the average person weekend warrior mom's kids, you know, it's really my recommendation is to go with CBD straight up at CBD. And that way, you're getting benefits like reduced pain and inflammation, reduced anxiety and other chronic conditions and CBD just allows a person to feel relaxed. Eight. Go ahead. I'm sorry. Go ahead. Well, it'll leave it's not it's not addictive. It's not toxic. There's no side effects, and it's fairly inexpensive. And THC cannot say that statement it has the exact opposite. I want you to go back said something, that's really really important. He said that. CBD is a SuperFood or can be like a SuperFood like vitamin. So is it a vitamin is it a drug is it a a medicine? That's a great question. And I think that all of the regulations are still being worked out, but I consider it. It is sold like a vitamin, and I consider it to the SuperFood at SuperFood to me is something that you can eat, and you can take in high doses and continue to get all kinds of nutritional digestive mental. There are logical and endocrine benefits from so the entire body benefits from a SuperFood. So think people think of go g berries or spirulina superfoods, and I'm really recommending that people think of CBD as a SuperFood. It's anti-aging. It really helps modulate all of your hormone. It said to think of DVD as like the dial on your radio like if you're trying to really find static. And so, you know, CBD cottages gets you to that place where they like. Oh, I could hear this perfectly clear. You know? That's exactly.

THC cvt
"thc" Discussed on Biz Talk Radio

Biz Talk Radio

04:34 min | 1 year ago

"thc" Discussed on Biz Talk Radio

"So from without the CD, and when somebody's nervous system is constantly firing. It's like their body is making rust all day long. And when you put the CD, and it just like takes that out of the factor. It takes it out of the Knicks. And we always have to say, yes, it makes tremendous sense. And we always have to share with people that that means that you don't get high. There's no THC, and that's our biggest. Educational piece on this program is is to distinguish but there are so many benefits. And so if you can talk a little bit about. Why you love the CBD, and the fact that you will never get high. So we could we could both write consume gallons and gallons of CBD oil. Hemp oil full spectrum CBD oil and never ever get high. Right. There's no there's no psychedelic type of effects like that CBD the way I describe it to my patients to my friend is you might feel in a way as if you had a glass of wine or a few just finished a yoga class. You just have that like. And your body, but your brain is more, sharp and focused and clear, then you can imagine without because when you take that stress and all that monkey mind or mind chatter out of the way are all your to do list all day long. You just clear, and that's really how TVD makes you feel and the that I use is more of a super food, and it's considered a vitamin sold like a vitamin and the regulations with that do not allow for THC to be in there. I can't speak to what maybe at some of the dispensaries around the country and that are growing popping up. They don't believe they have the same regulations. But when you purchase the CBD as a vitamin at a SuperFood. You are definitely not getting THC in there. I there are compound. There are products that do specifically say, they're THC and CBD. But those are usually really labeled clearly, and there are some people that like the benefits of having both, but for the average person weekend warrior mom's kids, you know, it's really my recommendation is to go with CBD straight up a CBD, and that way, you're getting benefits like reduced pain and inflammation, reduced anxiety and other chronic conditions and CBD just allowed a person to feel relaxed. Eight. Go ahead. I'm sorry. Go ahead. Well, italy. It's not it's not addictive. It's not toxic. There's no side effects, and it's fairly inexpensive. And THC cannot say that statement it has the exact opposite. I want you to go back. You said something that's really really important. He said that. CBD is a SuperFood or can be like a SuperFood like a vitamin. So is it a vitamin is it a drug is it a a medicine? That's a great question. And I think that all of the regulations are still being worked out, but I consider it. It is sold like a vitamin, and I consider it to be a SuperFood of superfoods to me is something that you can eat, and you can take in high doses and continue to get all kinds of nutritional digestive, mental and neurological and endocrine benefits from so the entire body benefits from a SuperFood. So think people think of Goldie berries or spirulina superfoods, and I'm really recommending that people think of CBD as a SuperFood. It's anti-aging. It really helps modulate all of your hormone. It said to think of DVD as like the dial on your radio like if you're trying to really find tune the static. And so, you know, CBD cottages gets you to that place where we like. Oh, I could hear this perfectly clear. You know?.

THC CBD Knicks TVD Goldie italy
"thc" Discussed on Biz Talk Radio

Biz Talk Radio

03:19 min | 1 year ago

"thc" Discussed on Biz Talk Radio

"So from without the CD, and when somebody's nervous system is constantly firing. It's like their body is making rust all day long. And when you put the CD, and it just like takes that out of the factor. It takes out of Knicks. And we always have to say, yes, it makes tremendous sense. And we always have to share with people that that means that you don't get high. There's no THC in. That's our biggest. Educational piece on this program is is to distinguish but there are so many benefits. And so if you can talk a little bit about. Why you love the CBD, and the fact that you will never get high. So we could we could both write consume gallons and gallons of CBD oil. Hemp oil full spectrum CBD oil and never ever get high. Right. There's no there's no psychedelic type of effects like that CBD the way I describe it to my patients to my friends is you might feel in a way as if you had a glass of wine or if you just finished a yoga class. You just have that like. In your body. But your brain is more, sharp and focused and clear, then you can imagine without because when you take that stress and all that monkey mind or mind chatter out of the way are all your to do list all day long. You just clear, and that's really how CBD makes you feel the CD that I use and more of a SuperFood, and it's considered a vitamin sold like a vitamin and the regulations with that do not allow for THC to be in there. I can't speak to what maybe at some of the dispensaries around the country, and that are growing and popping up. They don't believe they have the same regulation. But when you purchase the CBD as a vitamin at a SuperFood. You are definitely not getting THC in there. There are compound there are products that do specifically say, they're THC and CBD. But those are usually really labeled clearly, and there are some people that like the benefits of having both, but for the average person weekend warrior mom's kids, you know, it's really my recommendation is to go with CBD straight up a CD, and that way, you're getting benefits like reduced pain and inflammation, reduced anxiety and other chronic conditions and CBD just allows a person to feel relaxed. Wonder he eight go ahead. I'm sorry. Go ahead. Well, it'll leave it's not it's not addictive. It's not toxic. There's no side effects, and it's fairly inexpensive and THC. It's cannot say that statement it has the exact opposite. I want you to go back. You said something that's really really important. He said that. CBD.

THC CBD Knicks
"thc" Discussed on WBZ NewsRadio 1030

WBZ NewsRadio 1030

04:27 min | 2 years ago

"thc" Discussed on WBZ NewsRadio 1030

"Fifty three hundred and six hundred milligrams and I was it was recommended. That I get the six hundred milligram I take one drop of that under the tongue in the morning. And it seems to work pretty, well so those mean, different? Milligrams sizes those different sized bottles right No I think I think, it's concentrate 'cause I make the mistake a lot of they will label. A a large neuron milligrams on outside of the bottle and it looks like each dose is that but. It's not it's really like if, you get a jar, of One hundred twenty milligram, pills they're going to say two thousand milligrams think wow that's a lot, what's really, each dose so be careful about that. Right there's also Joe there's also sorry Matt there's also, the difference between whether or not the. CBD is. An isolate or whether, it is coming. Whether it's full spectrum and. And coming, from the full plant CBD is you know requires cannabis to be sent the sized some people are able to. Take it as a nice let, and have have a good effect others aren't? So, you know you you want to. You can experiment with that. At NATO we offer affordable one CBD ratio CD THC and a one to one also, exclusively CBD and also exclusively THC so you, really can you. Know experiment figure out what works best for you Excellent thanks Matt freesheet it pleasure, tiny Bo thank you thanks for your call Yeah that's Go to the menu let before we go to. The menu see if I have any. Other question. Oh yes I asked this before the show again when you talk about, the flower. Meaning, the The plant itself not an edible, not an not an oil not concentrate you you. Get to talk about all kinds? Of very specific strains super-duper specific strains with very specific percentages of stuff when you get to the edibles concentrates you don't get to have that choice in specificity can you explain why that is the edibles are. Are what is a small small piece of, a larger group of marijuana infused products or mips so, you you get mips by taking cannabis and the stilling it into, a super find pure oil so it. Doesn't matter where it's coming from where it's originating from which plant or. Strain. That is you certainly. Can take a specific. Strain and make something with it but. Boy down and getting the outright and. So the. The ratios that occurred in the flower, don't exist anymore correct and that's, why right Super pure oil you can. Add back in those turbines for flavor in effect really and you'd have. People. In the lab doing Oh yeah He's a. Great guy what what kind of school did they go to learn how to do that. Varying schools, I mean, you know cannabis is certainly as possible for people to go to school to learn the science of. Infusion this this is not a new process just applying. Its cannabis, they're? Chemists right but there are also people who did learn, this through, you know at their house growing cannabis on. Their own, I mean, you know we've merged into the regulated. Market now so by, the way what are the qualifications for the personal service these systems to tell? You, what The service What kind of background do you have to have to do that? Job, we well we like people obviously who have an enthusiasm and understanding. For cannabis we really like people who come. From healthcare you certainly don't. Have to we want the people who are the most qualified to do the job and her going to do the job best patient service is what it. Sounds like, you know. You're there you've got to make assessments and you have to listen. To people so obviously, listening skills, people skills Well I mean you need to exude. Confidence but, but really. It's understanding you need to be able to listen to what a. Patient is saying and, help them Yeah there's a. Lot of people coming in you know Susan might, come in one day and she's afraid of cannabis she needs that someone, who is, very sick might come in it might be. An. Adult, with her, small child a wide range, of, people that are gonna come in and need service and we're we train our folks intensely to handle that okay Now you might want you folks might want. To if you have a computer play.

cannabis Matt THC NATO Susan Joe marijuana Bo one day