31 Burst results for "Sern"

"sern" Discussed on Northwest Newsradio

Northwest Newsradio

01:42 min | 5 months ago

"sern" Discussed on Northwest Newsradio

"This city for more than ten years. And this is new. We never seen so many students and the crime this bad. Ever police officials, they didn't tell me they are working on trying to solve these cases and they're asking for anybody who might have been a witness to any of these shootings to come forward, reporting an effort, Paul Rivera. Seattle mayor Bruce harrell says he's trying to mend a strained relationship with the city council. I would describe it as extremely productive and collaborative. The issues I have with the council, I try to address the bad and the media or in public. However, there are still major policy differences on police funding, the homeless crisis, and parking enforcement. A legal challenge hopes to strike down an effort by the city of Seattle to make housing more affordable. Northwest news radio's Jeff pojo explains. The policy in question is Seattle's mandatory housing affordability program. In short, it requires builders to set aside a certain number of units to be rented at below market rates or pay additional fees to help the city build other affordable housing units. But Anita Adams says the program has added more than $77,000 in permitting fees just for her to build an auxiliary dwelling unit for her family on her property. Attorney sern John sen says that violates the constitution's takings clause. The city is using the permitting process as an opportunity to obtain the property that it wants. In this case, the $77,000 in permitting fees or additional affordable housing. The lawsuit was filed in federal court so far the city has not commented. Jeff pojo and northwest news radio. Northwest news time is 7 34. Let's get a check of our roadways on this Thursday evening. Natalie Melendez is in the dubin law group traffic center. Velveeta takula on top

Paul Rivera mayor Bruce harrell Seattle Jeff pojo Anita Adams city council Attorney sern John sen Natalie Melendez dubin law group traffic center
"sern" Discussed on Red Blonde Fox

Red Blonde Fox

09:48 min | 1 year ago

"sern" Discussed on Red Blonde Fox

"Day. The challenge route are teaching right now. Power in and we are a future now also through our right mean however knows actors cars and low four and aware so this also rats right now but we are grass in your area. Having or her is a is so he goes carolyn. Paris trial lasting are thing aurorae natural meaning. That other serves me my four out here live out. Not that attitude allan constantly. Here's trying find humor. In china. everyone cranky action. learn now here for lillian. Celebrate long celebrate the need this sumi enter the year. Your mind you. So we as adults have to in our current again him in sometime of your insecurity army given i have not. Thanks giving our fighters are you to her cursory. Hey missionary round. Shouldn't right doc in your federal company here are no matter what talking about conditions are heading the form ready under the free. They know that was really not only throw. Should you your living room freeman church in charge investors around her over ory you're the sern- for and that's what i'm not our heard. Closer relationship wins. You excellent about church. People you got relationship who shorts People and search prior raw ore. Here's your mesh. Hers was kinda racing everything to remain thankful tradition in invasion..

"sern" Discussed on The Larry Elder Show

The Larry Elder Show

05:43 min | 1 year ago

"sern" Discussed on The Larry Elder Show

"The larry elder show. I welcome back to the larry elder show just again a quick update on the larry elder race of just going through the news. Here this is an exclusive from exclusive from mike sern of it He said if we have a fair election larry elder takes it but have no fear like elder dot com elect dot com elect elder dot com. Mike serna vich author filmmaker said republican gubernatorial candidate and talk radio host. Larry elder would become governor of california if the recall election is above board If we have a fair election. Larry elder takes it Arnovitz remarked Even if it's not fair. I think that the margin of victory could be so strong and favor of the recall that there's not much that they're going to be able to do so. This is a huge important election. I think it's more important than any election up till twenty twenty two by far and honestly i encourage you guys to go out and just i mean just put the smackdown. Just put the smackdown you show up if you're concerned about balance. don't listen. don't get all hot and bothered show up show up and make sure that your vote is counted. I wasn't aware of until a week or so ago that you guys could vote in person so show up and make sure okay so today is the last day to you know what time with the cut off. Time in sean. Okay okay. so today's the last day to register to vote Out there so make sure you you you show up to make sure that your voice and your your boat your voices heard your boat is it is counted. And that's it and of course. I you you vote are recall. gavin newsom and. Then you vote to replace them with With larry elder and honestly the guys running strong. They're attacking him so viciously because they're afraid why do you think newsom is naming him of all the candidates initially initially. I think there were like over. Forty something candidates I mean it was outrageous. But gavin newsom goes after larry elder and that's because he's having the most impact so elect elder dot com elect elder dot com guys. You guys forty six or forty. Six candidates including larry and gavin newsom is naming him specifically. That's who they fear that means. That's the man that will do the best job for your state. I want to get to Election integrity before. I do that actually let me talk to you about food for the poor and then i'm going to take some calls. We're in our final forty eight hours of my food for the poor campaign to help. Children and families hit by the recent seven point. Two magnitude earthquake over the weekend. I thanks to my listeners. Like you We close in on over fifty five thousand dollars in donations as people went to larryelder dot com and click on the help haiti banner food for thank god for all of you guys out there that donated and i hope that you'll continue to do so. Boo for the poorest pod. Jacobs a assures us that every dollar donated is being rushed to haiti. Do context made over there. Thirty five years working on the island. Do we have more than a dozen. Boot centers run by community leaders across the country. That are helping for the poor. Get into a far-reaching areas. So that when you give right now. Clint that help haiti. Banner your guest is going into the hands in resourcing pastors local industries community partners. That have been vetted for thirty five years that are going to do the best work and have the most impact but remember my campaign ends tomorrow. So if you haven't had an opportunity to join our efforts and listen guys. I understand that life gets tough. But i want you to imagine the hurricanes if people are experiencing right now that that up pray for those people but also imagine the people in haiti that went through significant earthquake. And we're absolutely devastated. Just seems like they can't catch a break out there so please go today right now to larryelder dot com and click on the help haiti banner. Or you can phone in your generous gift to eight five five nine one. Eight four six seven three. That's eight five five nine one eight hope and thank you for sharing the love of christ through our friends at food for the poor Let's take a call real quick. We have mark in detroit michigan mark. You have the mike and you have many you make it happen. Yes sir. thanks carl for taking my call I just wanted to very quickly car. Search on this afghanistan the bockel up and pondering the last week And trying to come up with some kind of rational Idea why on earth this administration with fully are one of the most heinous terrorist organizations in the world who've been killing americans for the last twenty years collingwood hesitate to kill. You have given a chance. Why on earth would this administration fully arm. Give them some of the best weapon thinking by. We have just fully this. This terrorist organization have more sophisticated weapons than a lot of governments on earth. Does carl and i wanted a passable mark. Stay on the line. Stay on the line. I want you to finish your call. We'll be back after the break. Carlin for larry. Carl jackson will be back on. The larry elder show changed ninety. Five percent of americans live in what we call the fiber gap over nine and ten. People are deficient in fiber. Larry elder here you see fibers. One of the most well studied nutrients of all time..

Larry elder gavin newsom mike sern Mike serna vich Arnovitz haiti newsom earthquake sean california larry Jacobs Clint carl detroit michigan collingwood afghanistan Carl jackson
"sern" Discussed on The Dan Le Batard Show with Stugotz

The Dan Le Batard Show with Stugotz

03:43 min | 1 year ago

"sern" Discussed on The Dan Le Batard Show with Stugotz

"And then it goes to michael jordan and gets handed over it flourishes it becomes a global sport and then all of a sudden and it goes from being two black sport and a drug infested sport that couldn't reach white customers to being cleaned up everywhere. And then you arrive at this. I've got footage all over all day of what looks like a riot. In my sport. I got giant. Black dudes with corn rosen tattoos punching my highest paid tickets members through the front row punching them in the face. I have a public relations disaster on my hand. How do i fix this. I'm going to bury the players. I'm gonna bury them. I don't wanna hear their stories. I don't want to hear anything. I'm gonna bury the players so people can see. I'm a hard line commissioner. What did he do other than protect his business is business is not to protect the players. His businesses protect the owners. His business doesn't exist without players. That's naive like it's so naive. it's naive. But it's an argument that you've made on behalf of the players union. Another sport so guiliani aspect. That was not a partnership they didn't punish those players with the collective bargaining agreement through the union. They punish those players. They had a pr problem and they had to bury those players. That are stories. Didn't matter they were gonna get monster games as a suspension. That was gonna be unprecedented because all over televisions everywhere. It looked like the black players were out of control corn rows tattoos punching his customers right. But david sern as you mentioned you mentioned. The league had a very bad drug problem. Any the julianne on the aspect of it is that he helped clean up the league and so he was an extra disciplinary. It was just a reputation. Problem wasn't a drug problem. It's just they had a lot of black guys and they needed to sell it to the white customers and it had to be. It had to be a sport that was embraced by white people and it was because michael jordan and magic johnson were not what stephen jackson and run. Our test are like the entire image of the league was born with sneaker commercials and these black dudes who were there. Specific kind of role model hero black dude and germaine neal was that except for the packaging and he had to fight for ten years in court to get his name back jermaine. O'neal made the leap that the young guys can't make was not contaminated by making the leap from high school to know college. Who was the story. That amine was telling us about a guy who's afraid to leave. That didn't didn't want to miss the team function because he didn't understand dry cleaning and didn't understand laundry service and didn't have close to go to a team function because his closet was filled with dirty laundry and when when the team thought he was irresponsible but he was just having trouble with the transition. I'm forgiving kwami. That is the story. Thank you jemaine. O.'neil leapfrog all of that and was again right before all of that happened. I remember the prom photos. This dude took a stranger to prom just because he was a hero and that was what his reputation was. Here's the clean cut guy and now he's fighting to defend his teammates and a brawl gone sideways on the road. When he's got fifteen guys and he's got run our tests. Ticking on scorer's table. It's the subject matter so rich that i too would say what jessica's review of it is like. It's an above average documentary. It's an easy watch. And it's well done i just i wanted a little more from it. Gimme some laughter here. This was very serious. Give me some laugh. Some sui laughs. How long is this category. Just a couple minutes. can you give me some. Can you tease some of it. Let's.

michael jordan david sern guiliani germaine neal julianne stephen jackson magic johnson kwami jemaine jermaine neal neil jessica sui
"sern" Discussed on The Bobby Bones Show

The Bobby Bones Show

04:04 min | 1 year ago

"sern" Discussed on The Bobby Bones Show

"I don't feel like this is a top five songs from the decade but nothing makes me feel like that more than strawberry wine. Oh yeah i can see the video. I know exactly where i was and that to me is what essential ninety song means and then finally gotta put an early. Tim mcgraw song on there. And i picked. Don't take the girl. Jamie johns take tommy. Tom sern best friend. So if. I'm starting the list. Those three go on that list. Amy what is your nineties. Country song essential. Feel like there's some early ninety some late nineties. That are amazing. But i decided to go with on right in the middle and.

Jamie johns Tom sern Tim mcgraw tommy Amy
"sern" Discussed on This Week in Tech

This Week in Tech

03:12 min | 1 year ago

"sern" Discussed on This Week in Tech

"Couldn't stream it's one way it's it's one way only yeah And by the way the data packets are one hundred ninety two bytes up to one hundred ninety two per packet so it's really a very low bandwith but suitable for us. Yeah yeah various. Companies like bechtel things in their bridges. They put sensors in that when they're walking when they do the bridge walks they can walk over the bridge. Actually bechtel's big in the bay so they walk across the bridge they can tech if there's any cracks or any issues that you're having with the cabling or whatever so yeah. This'll be cool. Because i'm i was just looking at the picture here in and even with like you can tell if you're having some problem in the field you can just send a signal and then someone knows to get there right away and solve it. So yeah it's kind of cool or wrap things up with a happy birthday to the world. Wide web launched thirty years ago august. Sixth the very first website. Ever launched tim burners lee august sixth nineteen ninety one Was actually said. The worldwide web w. Three is a wide area. Hyper linked something or other pretty cool. It's hard to believe this thing. We take completely for granted is only thirty years old. That you know is it was invented before or after a lot of us were born and pretty cool so there is a project to restore that page was launched In two thousand thirteen. A wait a minute then. Pr says here it is you can go there. Let's do it info dot sern dot c. h. browse the first website. That's it it's pretty basic wide area. Hyper media information retrieval initiative aiming to give universal access to a large university documents. Would you have invested money in this. If you'd read that sentence thirty years ago think so stacey find out about swarm. We'll talk again on wednesday on this week in google. We missed you terribly last. Two weeks can't wait to get your back. Stacy's website stacey on. I o t dot com. Subscribe to free newsletter. Check out the events. And of course you gotta listen to the iot podcast. Stacey with kevin toefl waffles. In your future. While something snacky. Because i am hon. Something snacky coming up. It's great to see stacey. Thank you so much for spending your sunday with us. We really appreciate it. Thank thanks your family to for a given you up. I'm coming over for a karen's a. Only geary anytime you say. I'll be there doc. Rock youtube dot com. I'm sorry karen's mom bomb. Yeah this is karen. make it to No i see. She don't have to cook. She has me and her mom so yeah cooking vice love cooking could deal man. You're a catch youtube dot com slash doc rock. Of course he is.

bechtel tim burners lee stacey kevin toefl Stacy Stacey karen google geary youtube
"sern" Discussed on Science Salon

Science Salon

04:14 min | 1 year ago

"sern" Discussed on Science Salon

"He is the executive director of essentially a- foundation. His work has been leading the modern renaissance of metaphysical idealism the notion that reality is essentially mental. Here's a phd in philosophy in the subjects of anthology and philosophy of mine and another phd in computer engineering reconfiguring computing artificial intelligence as a scientist. Bernardo has worked for the european organization for nuclear research sern and the philips research laboratories where the casimir effect of quantum field theory was discovered formulated in detail. In many academic papers and books. His ideas have been featured on scientific american institute of arts and ideas the blog of the american philosophical association and big think among others bernardo's most recent work is. The idea of the world a multidisciplinary argument for the mental nature of reality. He's also the author of why materialism is baloney out true skeptics. No there is no death and fathom life and to life the universe and everything for more information freely downloadable papers and videos cetera please visit bernardo kastrup dot com. Okay well it sounds like a real jargon guinea kind of conversation we're going to have but it was. It was It was quite clear and lucid. you didn't you don't have to know anything about any of these philosophical topics to understand What he's talking about. And since i'm not a philosopher. It's easy to keep the conversation a practical so we deal with all the subjects. I just listed an and lots of very specific things like Altered states of consciousness and Hallucinogenic trips iowa lsd and so forth and The subject of near death experiences and out of body experiences in anomalous neurological experiences. We talk about e even alexander who had a trip that he went to heaven and In oliver saxes many works In this area of anomalous neurological experiences that people have the experiences very real. And so we talk about to what extent these opened the doors of perception to some other reality or not and then we Wrap up talking about free. Well and we're agency comes from and then suffering and the meaning and purpose of life at the very end so it was quite the conversation much much better than i thought it would be and and In super interesting so. I hope you enjoy the conversation our you where are you am in the south of the netherlands very close to the border with germany and belgium very closely jennifer's place close to cologne. Yeah that's right my wife's from cologne. Yes well we. We love that area. We haven't been there since the shutdown and it and it was probably a year before that we had visited so now it's been over two years. Now it's pretty crazy so Well as you know. I usually have guests with with a new book out you. Have you have several books to the latest. One on schopenhauer. I didn't get a chance to read. I did read through your Cheekily named materialism is baloney. How true skeptics. No there is no death and fathom answers to life the universe and everything okay with that bowl title. Why don't you give us a little bit of background. Who are you where you from where you go to school and i had to. Phd's very impressive So give us a little bit of background. How you got into this whole field of study originally buy education. I am a computer scientist engineer. Very early my professional life. My first job actually was at cerny switzerland. The big accelerator. In from dan on i worked latina ai. And of course when you're designing something that they suppose- supposed supposed to be intelligent. You ask yourself the question. Could it be conscious to any fears. What what would. I have to do to make it conscious in other words..

european organization for nucl philips research laboratories scientific american institute american philosophical associa bernardo kastrup Bernardo bernardo south of the netherlands cologne guinea iowa alexander belgium jennifer germany switzerland dan
"sern" Discussed on Stuff You Missed in History Class

Stuff You Missed in History Class

07:29 min | 2 years ago

"sern" Discussed on Stuff You Missed in History Class

"So to move on. Researchers have been trying to figure out the age of the sern- giant which is a chalk figure on a hillside in dorset england. This chuck figure is very large. It's fifty five meters tall. It's also very distinctive. It depicts a naked male figure wielding a very large club. Very naked. Ever seen this thing. it's super nude. The first written documentation of the figure is an account if it being repaired in sixteen ninety four and there's no mention of the figure in a sixteen seventeen survey of the area. So there's you know some people who wondered if it was made in the seventeenth century but it just seemed like something much older than that right in appears as tracy said so much older and after finishing sediment analysis the national trust has announced that the deepest oldest chocolate or the figure date to between the year. Seven hundred eleven hundred. So it's possible that the figure was created during the medieval period but then forgotten about or neglected and allowed to grow over in grass before being rediscovered. There's no evidence that the grassing over was intentional. Though one thing that they found when they were examining these chalk layers though was microscopic stales which. I also love. these snails. Were introduced into britain in the medieval period. There are still cement answered questions like who made this and why and who is supposed to depict Here's an idea so in nine hundred. Eighty seven sern abbey was established to try to convert the local population to christianity. They had previously worshiped. God known as high or health so this may perhaps be meant to be a depiction of that god and speaking of nudity. A carved piece of soapstone has been unearthed at vince. Landa which is place that we've talked about a lot on. Unearth before this piece depicts a naked male figure in front of a horse or donkey holding a spear and this went on display at the vendor linda museum on july first after having been found it looks almost as though he has a pacifier in his mouth but that is most likely just how it has worn over time. Although how funny would it be. And that is where we are going to stop until next time all right as promised. Tracy unearth related email. Have unearthed related. Email this firm katie. And katie says dear tracy and holly greetings from cardiff wales. I hope you and your loved ones are all safe and well at this point in the pandemic and that things are looking up in massachusetts and georgia. I'll apologize in advance for the novel. I have written below. I'll pause and say. Do not apologize for the novels really good novel. I'm not gonna read a whole one hundred percent of it today. But i saved it for this because it is so specific so k. Talks about being a bio archaeologist and working on a phd and and then says not so. Recently i was lucky enough to work with my friend and colleague jess on her project. Which very recently made headlines for her master's thesis jess examined diet and mobility of eight crew members of the mary rose ship using isotope analysis. I then contributed further us. Geological analysis on three of them. I know the mary rose has appeared on the sixth impossible episodes about shipwrecks. So i won't rehab it here. Though i say as an archaeologist it was an honor to analyze these men and help tell their individual stories which are often swept up in the narrative of the ship and re popular tailings just discovered that three of the eight analyzed were not local to the british isles with possible origins in the mediterranean spain. Slash the iberian peninsula and or north africa. We also identified that three of the eight where people of color one of whom was local to the british isles. The peer reviewed publication. Attached of this work will come out later this month. And because of that it received some press on this side of the pond at least and then katie linked to the to the article all that interaction to say as an avid steffi misty. History class listener. I realized this may pop up on earth. And if it does. I was hoping y'all might take the opportunity of highlighting a few things that some of the media missed out on some of the public comments. We received through that media. Mostly i think some of the summaries in the news made it seem like the diverse origins were based on artifacts found near the remains alone and i wanted to highlight. This absolutely is not the case. This work is based on stable. Isotope analysis elements extracted directly from the remains that are reflective of the food. They ate and the environment where they grew up. The online comments were interesting to read and seems to be a contrasting mix of people saying they already knew all. This work was featured in a documentary in the updated museum exhibit twenty nineteen and people saying that we were forcing a quote woke agenda of diversity onto the past where it didn't belong my favorite comment being a simple tweet. The mary woke ha-. I can't believe i have to say it but there was no ulterior agenda in this research just felt passionately about this project because she grew up near portsmouth where the ship now resides and has had a lifelong interest in it and as the lead researcher of the study just was determined to make the article open access meaning that the methods results and interpretations are available for free to anyone interested. We're very transparent about all those steps in their and our emails are easily searchable. Then katie has a tip about how if there's ever a peer reviewed article that you really wanna read and it's behind a paywall a lot of the times. The researchers will email you that pdf because they're not really making any money off of the journal publication process or the fact that the journal is trying to charge you fifty dollars to read one article one time but also katie talks about The the methods that were used for ancestry estimation there are lots of different conversations about how to do these kinds of studies and whether there's methods are ethical and so katie says quote. I understand people have doubts or questions about them. In this case we decided that not sharing. The results of these methods would only feed white nationalist narratives that we have shown with the physical evidence is false and then katie goes on to say that was not the goal of quote forcing diversity into the past. They were not about to hide that diversity having actually found it so katie goes on with a bit more. That i'm not gonna read through olof because i want to kind of wrap up the episode at this point but this was a great email to receive. I don't think i had found this particular. Find when i got the email and when i looked at it i did have the exact same response that That katy mentions of sort of saying well. We already know that. A lot of nautical cruise were a lot more diverse. Because it was a there was a more opportunity a lot of times for people to be able to through the ranks on a ship. Then they might be able to do you in a comparable job on land but having gone through and looked the stable isotope analysis to really.

katie dorset england sern abbey linda museum Tracy unearth cardiff wales tracy jess Landa steffi misty chuck mary rose vince iberian peninsula britain holly north africa massachusetts
"sern" Discussed on The Moratorium

The Moratorium

03:16 min | 2 years ago

"sern" Discussed on The Moratorium

"I am more than okay with that. I started looking at another actor here by the name of peppy. Sern yes got a couple of tabs on him yet. So peppy cerna was actually. He played reno. Nevada in the adventures of buck grew banzai. Yeah i he's been around for quite some time once you see him. It's like oh yeah. He has a very memorable face He was in the jerk He was in scarface. He was in american me. A right with the edward. James olmos and and look at that. It's william forsythe edward. James almost peppy cerna and a japanese guy that he was in Seems kerry hero yuki tagawa. He was them showdown in little tokyo. He he's having sex with the prostitute and then cut her head off while he was having second I mean all right. Like i didn't make the movie i'm just reporting on it but it actually is a pretty good movie. And has it's very quotable brandon. Lee says he wants to eat sushi off of naked chicks There's a lot of talk about doll florins weiner and possibly to but of course yeah i mean. Obviously peppy. Cerna was in out of bounds. Do you remember out of bounds. I bride or anthony michael hall. I loved this movie. And i'm afraid to watch it again. The thing that not gonna hold up. Yeah he was a anthony. Michael hall's like i like kinda serious turn. i guess. Sure if he could do drama eighty six. He looks pretty young pretty young. I remember liking it. Probably because i just liked him. You know from weird science which was probably my favorite moving who peppy. Cerna was also He was in red dawn. He played aardvarks father and red. Don sure we all know aardvark. Yeah who are for fuck was that it says what it says. The fuck is aardvark. Hey was in silverado. He played squatty and silverado. Yes that that's the one that i i sure. Know him from recognizing Aardvark was doug toby. Okay oh my god which has a connection to another film. Don't look him up. I'm going to tweet damning looking at it all right. We'll go ahead and tease it. That yes i did. Watch summer camp nightmare. And i will be covering that next week. Hey great thank you for doing that. Forest us but Yeah doug toby he definitely is one of the disposable red dawn kid like i know all of these brad packers you guys better watch out because you're not long for this world in a red shirt. He was also an oh..

Sern cerna Cerna James olmos william forsythe edward peppy cerna yuki tagawa reno anthony michael hall Nevada kerry doug toby edward Michael hall weiner tokyo brandon James Lee Aardvark
"sern" Discussed on The Adventure Zone

The Adventure Zone

05:41 min | 2 years ago

"sern" Discussed on The Adventure Zone

"During a mission to find the vanguard. The cartographer phineas call was betrayed and killed in action. His departed spirit was somehow recovered by his scientific fellows. Called the deep thinkers and placed in a brian our body alongside five other spirits becoming the entity called hamper sand five. This resurrection was protested. Both by the parish and it's ultra orthodox offshoot the ordos spiritus shortly after phineas calls ill-fated mission. A disease called the sallow took hold of the community. Quick preventative action kept losses to a minimum but those who were afflicted began to grow subtle fish like features most common among them being catfish whiskers the council of four a ruling body with representatives from each of the four kingdoms was overthrown following the loss of the child of declan sern the representative from hominoid in the chaos that followed the bow. Your her formed a new system of government. The ballast where representatives from the community's various workforce's and factions would come together to make the decisions that would shape the community but the greatest hardship would come on the communities last day on the shore the capital of hama nine using impossible magic and guided by enormous flying. Wales was lifted into the sky and passed into the storm creating a tidal wave that forced the immediate and permanent evacuation of the shoreside community in their fleet of bathysphere houses. The people would leave the beach. They'd called home for the past year taking residence in their new under sea dwelling a city. They would come to call founders. Wake twenty five. Years have passed since that evacuation and in that time founders wake has expanded dramatically and enchanted tower that once connected the einar plateau to the world below called the crystal ascension sank to the bottom of the ether see during the construction effort it nestled against a sheer cliff face and now serves as the spine for founders wakes vertically stacked districts at the top of the crystal ascension sits the ballast the municipal hub and seat of government for the city. It was the first structure built below. The waves made from a repurpose arc gifted to the community from the southern archipelagos fleet immediately below. The ballasts sits the conservatory. The first expansion built by evacuees which houses the benevolent perish. And the curator's many museums parks and menagerie. He's the city's largest district sits immediately below that the forecast where rows of thousands of baths fear houses are arranged into ample residential quarters built into a towering hall resembling the bow of a great ship. The four castle surrounds and protects. Another district called the cradle named for a beloved shipyard constructed on the shore above within the safety of the cradle. The city's essential utilities and life support systems are maintained at the base of the four castle and unintended district. Took four within this deck. Less scrupulous operators could find cover from the ballasts watchful eye and when one thinks of unscrupulous operators one name came to mind and so this district earned the title of joshi's knuckle atop the cliff. A sprawling industrial complex called the gunnell was built to give fisheries farmers and salvagers the space. They needed to complete their vital work. Though that work takes place in the shadow of a cloud of debris remnants of the world above that have long since been sundered by the storm near the cliffs base the coral spire continues to thrive as the city's deep thinkers built a massive laboratory surrounding the structure in this lab far from the scrutiny of the parish in the ordos spiritus. The city's brightest minds continued development of new technologies while desolation continues the painstaking process of guiding the einar spirits into their new coral frames and at the base of the crystal ascension. The city's newest district called the gills hums with activity here. Ships of all shapes and sizes are built and maintained alongside a sprawling network of docs shipyards and modern commercial facilities. One such building belongs to a group called the blue span brokerage which facilitates the kind of undersea expeditions that might attract aspiring adventurers of a certain strike and it is here in the posh bustling headquarters of the blue span brokerage that our story begins..

phineas call declan sern phineas southern archipelagos hama Wales gunnell joshi
"sern" Discussed on The Phinsider

The Phinsider

05:08 min | 2 years ago

"sern" Discussed on The Phinsider

"Keep in mind the dolphins For some reason a full back on the roster for most of the season last year despite being mustache chandler cox despite being schalken team for most of the year. So you wonder is is carl talker. The the back for alabama is he going to take photos four spots and all of a sudden akkhmed brown and dokes fighting for two spots. I mean i. I don't know this is kind of going to be interesting topic to see the running back room developed. I mean everybody absolutely loved welcome. Perry he was going to be the next swiss army knife for the miami dolphins offense. He played forty percent of snaps in week. Fourteen but then he dropped ten snaps in week. Sixteen and ten snaps in week. Seventeen he was another guy who was phased. Out of the offense. It's going to be an uphill battle from. I think it can be practice squad guy. But i be. I just would like a little more consistency in the group. I mean i guess the best way to prove me wrong is is the saying of. You can find running backs everywhere anywhere. So of gaskin goes down for game. Two dokes in theory should be to step right in and be the guy because it's that simple fight running back. According to some according to some. Their diamond doesn't but another thing that stood out to me. Was you mentioned the fullback. And i believe too. I think asking made four. I don't remember how many touchdowns the untold. I remember of the touchdowns at the at the goal line. Christian wilkins was in at fullback as lead blocker so that was an interesting thing. And you know. I don't know that you would keep a carl tucker on the roster occupied roster space just like you might not chandler cox when you can just throw a christian wilkins gas in there. He's more than happy to take that role. Yeah and i think that is a very good point but again in his low concerning due to the fact they kept cox. Even though wilkins using a first-round pick on fullback is a little questionable but it seemed to work out for the miami dolphins taking christian. Wilkins there I think song i round he was in but he was basically a fullback. Good point i is christian next late non-binding say because that's going to get the article. V article licks. Let's do it. Oh man that would certainly be something else. But josh before we wrap up here i i do want to say i mean aren't to a show that that kind of blew up a little bit for us. Our most downloaded show. So i just wanted to say. Thank you for everyone who's listening. I mean it's the beginning of june. We're here talking about dolphins football. We understand it be silly. Sometimes but that's kind of what makes it fun right that we can enjoy the offseason not the panicking about our favorite team using every other week. If you would like to continue this ride with us hit with sky and that helps us. Not so much Whether on itunes whether on spotify you can find just about anywhere. I'm and then you know if you wanna give us a little confidence boost if you're really enjoying the show can't a couple of seconds to lever of you that stuff out and you know people who are looking at different shows read. That's up to so you're just helping others really discovered the show. I mentioned a couple times but be should apologize on twitter at ut. I can be found at j mendel ninety four on twitter and and josh. Do you have any other final words here before we wrap up. I have one final question. But if i don't wanna be the one to bring it up. I think you should be the one but being a professional journalist. I will ask the tough questions if you make me yet. You may as well just asked me the question because we know what what's on everyone's mind i just said it. There are two of show. What is our most listened to show and at about the twenty minute mark. Josh might of passed gas. Yeah just like that. So so that's kind of kind of fits our old where something a little goofy lakes that happens. Obviously we were talking about the receiving corps. Josh made that noise. Just kind of reacting to the stephen core giving some sort of analysis about the two thousand twenty miami dolphins and i thought it was pretty good analysis But it was also pretty real sounding to save the a lot of Listeners reach that does wondering what we think. He did in the middle of pod. So thank you. It was a good chuckle. And i hope he has enjoyed that to Those lovely have the aussies that we're going to have fun with this stuff. And we hope your to josh. Do you have anything to say for yourself. I cannot believe how many people like i know. Sern mentioned it in our group chat. And then i've had people literally reach out like they were concerned for my well being and you know my career moving forward but guys out was definitely that was definitely a mouse for and it came at the perfect time with other receiving core. But if you want to say. I farted charlotte. I don't care. i mean. I'll still be here one way or the other. That is all we have for today on federative to give you guys a little. Bit of a teaser. Mandatory minicamps are june fifteenth through seventeenth. I'm say recorded on june fourth. If you don't think we can squeeze everything we can edit this offseason prepare for next week where we give you twenty headlines to foul for the weekend. That is three days long. We're gonna do it josh. We're gonna squeeze all the content out of this thing as we can. We are in guys who that is a threat as one hundred percent threat. Jake guys thank you so much for listening to the inside radio. The jason josh. Oh i'm josh. How's that is the greatest in the world. jake mendel. We'll talk to you next time. Breath side radio.

jake mendel forty percent Perry twitter last year Sern carl talker Sixteen Fourteen june fourth core Wilkins ten snaps Josh two spots next week two three days spotify jason josh
"sern" Discussed on The Auideo Show

The Auideo Show

06:27 min | 2 years ago

"sern" Discussed on The Auideo Show

"The following month then taylor gonna play out. Thanks everybody for coming in. If you do leave we are streaming. This live on our. There's a qr code on all the tables. If you decide to leave you can listen to this whole thing until eight o'clock on your phone very nice. And we'll see you. Friday morning for all the idaho. Chauffeur's tweak right back thanks guys Sern scars on blue money. A struggle goals home with a show years ruled from the prison. A man you turned down then lifts certainly. Did you know A broke she held you here. She gave you two k. Steal I take the a to no So zoom skyser gray. His story god should soon took from your mother. Is you rams do and you you no sir. If you're wondering about today's schedule idea radio follow us on social media. It's armand every morning..

"sern" Discussed on Pond's Feed

Pond's Feed

05:08 min | 2 years ago

"sern" Discussed on Pond's Feed

"Talking adds some piano or mr jonathan rohan who so happens to be leading a sern products. Could you tell me about that. Yes Current project that i'm working on children of night chosen of night is a horror short. That is about a house sitter on the name. Days clark's goes in need of money for upcoming caused semester. So she takes a housesitting. Gigs from the mysterious and clear and This is a wealthy young power couple. Who are mysteriously also vampires and looking to recruit deja into their undefeated family beyond just House sitting on her. So this really fun. Horror thriller that Currently i'm gearing up to go into production supple mon- some running crowd funding campaign on on any dogo right now. So yeah. that's what i got going on right now. that is interesting. I saw the crowd funding campaign. Why do you need that. Adds in order to make this project or work our or is there alternative in case well. This project has been in development since two thousand nineteen originally. This products started out as a school project and do to us going into production and twenty twenty. Everything stopped La county was on lockdown There were no more resources from school and allow things froze and me and my team were very determined to still produce this project and brings us to light in spite of what was going on around us and not having financial means to really produce the project way would have been produced to film school so therefore we want to go ahead and do this power through trump through there so we need people's up wants to be involved in helping finish our go producing this phone. So that's where it across funding. Sorry about that. I m members For my little pup in the room sides a gal she by why to play catch river or chase around the room. So i had to get in case she has to use. The bathroom should won't have to do it in here. So slow things now. i wake background. You have by the way three. Zoom are with your as in green screen the poster and like what what served like ways. Have you been marketing. Besides like you said with an indigo goes away to crowd fund..

trump twenty twenty jonathan rohan La county three dogo two thousand nineteen indigo couple clark
Artists on the loose at the Large Hadron Collider

Science Friction

02:06 min | 2 years ago

Artists on the loose at the Large Hadron Collider

"At the beginning of the universe minutes after the big bang as temperature cooled the most fundamental particles of matter came into existence so neutrons protons photons electrons and others the basic building blocks of everything we know and see and much way died and to study these teeny tiny particles tucked inside every atom in the universe. invisibly are physicists. Nate this vast instrument one that occupies an entire vast landscape two hundred hectares of farmland. The contrast between big and small here cyber czar. We're about eighty eight meters underground. That the moment kilda. I'm jacob new-zealand. It's great we have people from all walks of life and all over provision who got physicists engineers computer scientists edmund people like me and they're all from different parts of the world i think from the star of the these filled like a mini country so i'm asking schroeder and i'm a experimental particle physicists. In i don't know somehow. When i leave sern i realized that i'm still honing in the normal world. I don't know some kind of refuge from everything else that is going on outside in the world and here science is what really matters. I feel like Since great that it's a kind of a political place you know. The relationship with russia never changed during the cold war with. We're about science purely about saying well not just science. I'm here for art to people as you'll hear science friction with natasha mitchell. Many meters underground this week and easter special from our archive inside the heart of soon. Just outside of geneva in switzerland home to the world's largest most powerful particle accelerator. The large hadron collider the hcc. Now this of course is the place where the elusive higgs. Boson particle was discovered. And where last week scientists hinted they just might have discovered a brand new force of nature or put it another way a violation in the standard model of

Kilda Nate Edmund Schroeder Natasha Mitchell Zealand Russia Geneva Switzerland Boson
"sern" Discussed on Feast of Fun

Feast of Fun

01:34 min | 2 years ago

"sern" Discussed on Feast of Fun

"The tv writer russell t davies best known for his pioneering queer as folk. And the doctor who reboot says. He's seen just about every televised drama about game man and as and now his new series. It's a sin which chronicles the lives of six friends. Living in london at the start of the aids crisis has become the most watched drama ever on britain's channel four the show is celebrated for capturing youthful joy of being gay in an urban environment loss showing the painful moments of the aids crisis. But it's a sin is also fraught with sensationalism and harmful portrayals of hiv and aids tropes as dr franken. Furhter would say how sentimental. We'll watch you mysterious faust. I was struck with how much the central character of joe baxter. Who is overwhelmed helping. Her gay friends manage the aids crisis. Reminded us of victoria. Knowing who came piece fun to talk about her book bags divas and moths the legacy of straight women in the aids. Community today victoria. No he joins us to take a look at russell. T davies mini series. It's a sern and what it was like for her. And her close friends living through the aids crisis i am fausto furnace i mark billion and this is feast of fun. It's not easy having a good time. These fun is made possible..

russell t davies london joe baxter six friends dr franken today victoria divas britain T davies four
"sern" Discussed on Scientific Sense

Scientific Sense

04:11 min | 2 years ago

"sern" Discussed on Scientific Sense

"Here's what is the process made off right. That's that's an excellent question. Actually well depends on the system. You study there are many different types of car applause must or approximately caro blossoms even if you take just Electromagnetic bosma made of electron electrons and positron so essentially when you Heat up Electromagnetic system System made electrons than extremely high temperatures that could potentially exist for example in Extreme environments nia complex stars near black holes or if you create plasmas made of works that could be sitting at the very core of super dance complex stars. Those will be the conditions on the which you approximately each the regime of the karo bosma. And that's where you might start looking for those conditions for those consequences. One other system would be the bras mma produced in xinjiang collisions such as it sern and brookhaven where they rely heavy ions at extremely high energies. And one this violent collision happens. You create super energetic lesion in space with gorgon's plasma that exists for a brief period of time but curious some information into the detector and we could analyze that those signals. Okay and you finish massless. Approximately massless approximately massless The thing is that neither walks. Snowy black trans. Naw most of the things that people are studying and calling them. Car clause must truly massless. So you might say that. I'm contradicting myself. Saying that there is that even though they're massive and massive the kerala can flip from one side to the other while the reason people are calling them. Approximate karaoke clause must that they have extremely high temperatures so using this famous einstein. Relation e. equals mc squared if the mass is small in terms of the relative to the corresponding temperature so in energy units if you express the temperature as suck mass time c squared so if that temperature will be much larger than the corresponding einstein energy equal. Squared mc squared than. You will see the this cozma becomes approximately carl. Because all of this car rally flip houses will be strongly suppressed by stanford. And that's when you could start thinking about possible implications of plasma and so So the kite magnetically Talk about the paper. nah bit about You save the propagation of those magnetically leaves The pasta could support that by while In fact we were queen of in this paper that you mentioned we are. We claiming Mike collaborators that in fact the laws not is actually not propagating. So when i say it's over them. It means that essentially a susan soon as i'm trying to create it it doesn't want to propagate it's like creating away in a honey it dumps very quickly and the thousand propogate now that is actually a relatively recent finding in your revision of some Suckled detail how it happens but For maybe like Years it was expected that they shoot exist. Very well pronounced. Carl magnetic waves and those paramedic are kind of very simple so imagine any way that you would typically find..

Mike kerala brookhaven stanford One other system one side one carl approximately each einstein sern thousand
"sern" Discussed on Beach Talk Radio

Beach Talk Radio

04:24 min | 2 years ago

"sern" Discussed on Beach Talk Radio

"Then iran police department and that's lee county ambulance. Hopefully nobody fell off their bike without a helmet on. So we're getting all the action today. Different here you have your own fire department and your own police department. No no the fire department is is the santa bella cap. Tv it. that's a county that has not that is not part of the city of santa bell. Okay at our police department. Yes we do have a police. Department services. Both areas correct and and i was remiss because when i said maybe i forgot someone chief dalton. He has been here for for decades and he is now. He's our current chief and put it in a good word for us. And maybe he'll come on the show. And i don't know but i can't. You know very lucky to have the leadership that we do on safety on this island. We're small island. So safety of our of our citizens of our guest is our sern. I guarantee you when you made a comment about somebody on this bike path. I guarantee you somebody on this. So you're you're saying how long you've been on the council So i was appointed for a four-month term. And then jim jennings moved off island. And i i finished his one year and then i am an to two years of my first four years. Okay so the other person that will be left after the election is on how long richard johnson johnson John says you know. Has you know his family. As of the bailey family. So bailey's grocery store. He he came on with me in this first in the first four year term He was on planning commission as well off. Their roots are usual. Basically the same amount of time on the board. And then you're gonna have to kind of well. You might have new members. You might have to new members and jason. Who's on before jason monitor's on before and do you recall how long jason was on before he had to resign to run for. He ran against Vote-on i think right. He was actually elected. I think there were four people running for three position so he was actually.

jim jennings jason two years richard johnson johnson first four years one year santa bell dalton four people four-month term today Both areas three position first first four year term santa bella cap John iran police department decades bailey
"sern" Discussed on Water and The Spirit Podcast

Water and The Spirit Podcast

03:58 min | 2 years ago

"sern" Discussed on Water and The Spirit Podcast

"Those who have accepted this truth as the light of salvation. God has made it possible for all souls to attain their true salvation answer preach it throughout the whole world. That's all of us can now become god's children that's everyone can now become. God's child is because god has completed the gospel of the water on the spirit for us just as god made this universe the domain that we see with our eyes on the heavens and the earth caught himself has also accomplish the salvation given to through the gospel of the water on the spirits. What a wonderful news is this. How could we ever thank god enough that we were able to become the light of the world when we really think about how we were born on this earth and yet could become heavens people. It is so amazing. And so thankful our salvation from sin did not spring forth naturally puts. It was made possible. Because god made us be born again on. Sern does into his own people. This truth of salvation. The gospel of the water and the spirit is such a great a marvelous truth. Nothing can this world can be more marvelous than this gospel. How could you have become. The people of heaven. got planned. mankind's future a made them become his people. We are only amazed and thankful for this if human beings were to plan the creation of the universe. Could they have achieved it. It is simply impossible. Furloughs humans to achieve this but from the very moment that god created the universe even before any human being was born on this earth he made everything for the purpose of making mankind. Be born again from san. What's wonderful plan. Is this as for myself. I can only found the lord for allowing me to spread the gospel and to serve him. There really is nothing new on this and to live for anything else but this gospel is only tiring itself however when we think about what is truly khotan said it is the fact that our court has made also his people. This is the most refreshing news that we are hot pizza here every day. That blesses those every time we think about and that remains perfect even as we think about it every day waltz is the most precious gift that god has given us. There is no other news better than the gospel of the water and the spirit that god has given us just this afternoon. I went out to evangelize with our brothers. What's better news is there for sinners than to spread the gospel of the water and the spirit to them. What greater and better gift is their facilities bum. Vicky about god has saved them from saint. What giving a box of fruit juice to the patients in hospital compared to the gospel word of the water and the spirit that we are preaching. Is there anything. That's his greater. Than the fact that god has saved us from the sins of the world there is nothing home they thought is great furrows mankind then the gospel of the water and the spirit god created us on the heavens and the earth from the very beginning. Got mehta's be born again on. They said to turn us into his own people in heaven and jesus christ gables the gospel of the water. The spirit's may does believe in it and be born again and indeed turns us into gods people..

Sern khotan san Vicky mehta
Dr. Mark Hoffman, Research Associate Professor at the University of Missouri, Kansas City - burst 01

Scientific Sense

44:57 min | 2 years ago

Dr. Mark Hoffman, Research Associate Professor at the University of Missouri, Kansas City - burst 01

"Welcome to the site of accents podcast. Where we explore emerging ideas from signs, policy economics, and technology. My name is Gill eappen. We talk with woods leading academics and experts about the recent research or generally of topical interest. Scientific senses at unstructured conversation with no agenda or preparation. Be Color a wide variety of domains red new discoveries are made. and New Technologies are developed on a daily basis. The most interested in how new Ideas Affect Society? And, help educate the world how to pursue rewarding and enjoyable life rooted in signs logic at inflammation. V seek knowledge without boundaries or constraints and provide unaided content of conversations bit researchers and leaders who low what they do. A companion blog to this podcast can be found at scientific sense dot com. And displayed guest is available on over a dozen platforms and directly at scientific sense. Dot? Net. If you have suggestions for topics, guests at other ideas. Please send up to info at scientific sense dot com. And I can be reached at Gil at eappen Dot Info. Mike yesterday's Dr Mark Hoffman, who is a research associate professor in the University of Minnesota Against City. He is also chief research inflammation officer in the children's Mussa hospital in Kansas City. Kiss research interests include health data delayed indication sharing initialisation Boca Mark. Thank you for inviting me. Absolutely. So I start with one of your papers Kato you need the use by our system implementation in defy date data resource from hundred known athlete off my seasons. So Michio inflicted. Data aggregated for marketable sources provide an important resource for my medical research including digital feel typing. On. Like. Todd beat to from a single organization. Guitar data introduces a number of analysis challengers. So. So you've worked with some augmentation log and in almost all cases be used. Data coming from that single macy's listen primary care behavioral. Or specialty hospitals and I always wondered you know wouldn't be nice. Get a data set. That sort of abrogates data from the radio on-ice. Asians but a lot of different challenges around that. So you wanted to talk a bit about that. I'd be happy to the resource that we've worked with. Is primarily a called health fax data resource. It's been in operation for almost twenty years. And the the the model is that organizations who are. Using these Turner Electronic. Health. Record. Enter into an agreement was turner they agreed to provide data rights to sern are. The identifies the date of affords aggregated into this resource. And certner provides data mapping, which is really critical to this type of work. It also the aggregate the data. And for the past probably six years. Then, they provide the full data set to especially academic contributors who want to do research with that resource. And I've been on both sides of that equation Lead that group during my career there, and then now I have the opportunity to really focus research on that type of data. So before we get into the details smog so e Itar Systems. So this is. Essentially patient records. So he gets dated like demographics out family history, surgical history hats, medications, lab solves it could have physician nodes no snow. So it's it's a combination of a variety of different types of data, right? A couple of things on the examples you gave it includes demographics. Discreet Laboratory results Medication orders. Many vitals so If access the blood pressure and pulse data. It does not include text notes because those can't be. Automatically identified consistently. So. We don't have access currently to TEX notes. Out of an abundance of caution. That his Hobby Stephen, physician writes something down they could use names they could use inflammation that could then point back to their. Patients Makita Perspective been the data's aggregated, the primary issue shoe that date has completely the identified, right? Correct. So. So yeah. So the data that we receive there's eighteen identifiers. Hip requires be removed from data. And those include obvious things like name address email addresses are another example One of the. Things. That is also part of the benefit of working with this particular resource. The. Dates of clinical service are not allowed to be provided under hip. White is done with this resource that allows us to still have a longitudinal view is. For any given patient in the data set the dates are shifted by A. Consistent. Pattern that for any given patient it can be. One two three four five weeks forward or one, two, three, four or five weeks backward. But that preserves things like day of the week effect. So for example, you see -nificant increase in emergency department encounters over weekends and you don't WanNa lose. Visibility to that. but it also allows us to receive. Very, granular early time stamped events in so. We can gain visibility into the time that a blood specimen was collected, and then the time that the result was reported back. And so we're able to do very detailed analyses with this type of resource. Right right and I don't know the audience our market is fragmented. Tau himself e Amorebieta providers out there. and so two issues. One is sort of. Standardization as to how these databases are designed and structured and others even that standardization that the actual collection of the data. In itself is not standardized played. So vk CAV vk potentially lot inability coming from different systems. Correct and that's part of what the paper that you mentioned Evaluates so. Often, night you out in the field in conferences you hear. Comparisons kind of lumping all organizations using one. Vendor lumping all using another together but as you get closer to it, you quickly learn that. It's not even clear. It's within those. Vendor markets. There's variation from organization to organization in how they use the e Hr and so. Because the identities of the. Contributing organizations are blinded to those of us who work with the data. We have to be creative about how we. Infer those implementation details, and so with this paper, we describe a couple of methods that We think move things forward towards that goal. Yes. So I'm not really familiar with that. So you mentioned a couple of things here. One is the the merge network. So this initiative including electric medical records and genomics network and pc off net the national patient, centered clinical research network support. Decentralized analyses that goes disparate systems by distributing standardized quotas to site. So this is a situation where you have multiple systems sort of. Communicating with each other and this net folks at allowing to sort of quickly them In some standardized fashion. So In this type of technology, there's janitorial core models. One is the. Federated or distributed model, the other is a centralized data aggregation. So there are examples including those that are mentioned in the paper where. Queries are pushed to the organization and. They need to do significant work upfront to ensure that there are standardizing their terminologies the same way. And once they do that upfront work than they're able to perform the types of queries that are distributed through those. Federated Networks. With. Okay. So that just one click on so that the police have standardized. So all on the at Josh site, then they have like some sort of a plan slater from from Stan Day squatty do all the data structure. And in many cases, they work through an intermediate technology. that would be. In general, consider it like a data warehouse. And so the queries are running against the production electric. Health record. That has all kinds of implications on patient care where you don't want to slow down performance. By using these intermediaries They can receive queries and then Follow that mapping has occurred. Than, they're able to to run those distributed queries. Okay. And the other model is You know. You say the g through the medical quality, improvement consortium and sooner to the health facts initiative. So this says in Sodas case, for example, in swags. This is essentially picking up data from the right deals, clients and Dan standardizing and centralizing data in a single database is that that is correct. One benefit of that model is that Organizations who for example, may not be academic and don't have the. Resources to do that data mapping themselves by handing out over that task over to the vendor you get a broader diversity of the types of organizations so you can have. A safety net hospitals you can have. Critical access rural hospitals, and other venues of care that are probably under represented in some of those. More academically driven models. And clearly the focus on healthcare about I would imagine applications in pharmaceutical out indeed to right I. Don't know if it s use and bad direction there has been some were performed with these data resources to. Characterize different aspects of medications, and so it does have utility in value. In a variety of. Analytical contexts. I was thinking about you know a lot of randomized clinical trials going on into Kuwait context and One of the issues of dispatch seem development toils that are going on that one could argue the population there are not really well to percents. it may be number by Auditees, men, people that deputy existing conditions. and. So he will serve at my come out of facedly trial. granted might work for the population. Tried it minority have sufficient? more largely. So I wanted this type of well I guess we don't really have an ID there right. So clearly, you don't know who these people are but they could be some clustering type analysis that might be interesting weight from It's very useful for Health Services Research and for outcomes research for you know what I characterize digital phenotype being. they can then guide. More, more formal research. you know you can use this type of resource to. Make sure. You're asking a useful question and make sure that there's likely to be. Enough patients who qualify for given study. Maybe you're working on a clinical trial in your casting your net to narrow you can. Determine that with this type of data resource. And is the eight tiff date who has access to it typically. So for this data resource on, it's through the vendor so. You need to have some level of footprint with them. which is the case with our organization. They're definitely a broadening their strategies. So they're. Gaining access into health systems that aren't exclusively using their electronic health records so. It's exciting to be a part of that that process. and to again work with them to. Analyze the data. I think. To the example you gave a formal randomized trials. In key part of what were growing our research to focus on is because this is real world data. You learn what's happening in practice whether or not it's well aligned with guidelines or formal protocols. And doing that there's many opportunities for near-term interventions that can improve health outcomes simply by. Identifying where providers may be deviating more from. Best Practices in than taking steps through training and education to kind of get them back towards those best practices. This data is a fresh on a daily basis. It's not. It's because it's so large and bulky? Typically we've received it on a quarterly basis in since it's retrospective analysis that's not been a major barrier. But. mechanistically, on onto soon aside is data getting sort of picked up from this system that it's harvested every day and then it's aggregated bundled and distributed on A. On a different timescale. Okay okay. So. From again, going to the, it's our system designed issue and implementation You say many HR systems comprised of more news at specific clinical processes or unit such as Pharmacy Laboratory or surgery talked about that. But then then people implement them this of fashion right they they implement modules by that can be a factor or sometimes they may want. One vendor for their primary electronic health record, but another vendor for their laboratory system. and so that's where you don't see a hundred percent usage of every module and every organization. And detailed number of different you know sort of noise creating issues in data one. This is icy speech over from ICT denied ten. and I don't know history of this but this was supposed to be speech with sometime in twenty fifteen. That's correct. So there is A. You know. There's a date in October of Twenty fifteen where most organizations were expected to have completed that transition. When I see with researchers who aren't as familiar with the you know the whole policy landscape around `electronic health records that? you can imagine researchers who assumed that all data before that date in October is is nine and all data after that date would be icy the ten. While we demonstrate in this paper, is that that transition was not Nearly, that clean and it was a much more, you know there are some organizations who just It the bullet and completed in twenty fourteen, and there are other organizations that were still lagging. In. Two Thousand Sixteen. Potentially because they weren't as exposed to those incentives in other things that you know stipulated the transition so. Part of why were demonstrating with that particular part of that work was that. you know these transitions aren't always abrupt. Yeah and and and so that is one issue and then you know a lot of consistency inconsistency issues fade. So we see that in in single systems and one of the items note here as you know if you think about the disposition code for death. you could have a right your race supercenter, right? It's a death expire expedite at home hospice, and so on. if this is a problem for a single system, but then many think about aggregating data from multiple sources this this problem sort of increased exponentially. Absolutely. So one of the challenges with documenting and and finding where you know if a patient has A deceased that. There's just multiple places to put that documentation in the clinical record. The Location in the record that. We have found to be the most consistent is what's called discharge disposition. By as we show in that analysis, that field is not always used document that and so if you're doing outcomes research and one of your key. Outcome metrics is death. And there are organizations that. Aren't documenting death in a place that successful. You should filter those out of your analysis before moving forward. And so part of what we wanted to promote is the realization that. That's the type of consideration that needs to be made The four. Publishing. Your data about an outcome metrics like death that. You're not. If you're never gonNA see that outcome it doesn't mean that people are. Dying in that particular facility, it just means it's not documented in the place that successful. Right. Yeah. So you know you on your expedience. Unique Position Mark because you you look at it from the from the vendor's perspective you're in an academic setting you're also in practice in a hospital. What's your sense of these things improving the on a track of getting getting this more standardize or it's camping in the other direction I think in general there is improvement I think The. Over the past eleven years through various federal mandates, including meaningful use and so forth. Those of all incentive organizations to utilize. Standard terminologies more consistently than was the case beforehand. I think there's still plenty of room for improvement and You know it's it's a journey, not a destination, but I think things have improved substantially. I was wondering there could be some applications of artificial intelligence here to In a clearly TATECO systems and you'd like the most them pity human resource intensive Yvonne to get it completely right. So one question would be you know, could be actually used a Dick needs to get it maybe ninety nine percent white. And that the human deal with exceptions I definitely think that that's an exciting direction that You want those a algorithms to be trained with good data, and that's a big part of what's motivated us to. Put this focus on data quality and Understanding these strange nuances that are underpinning that date has so that. As we move towards a in machine learning and so forth. We have a high level of confidence in the data that's training those algorithms. Right. Yeah. I think that a huge opportunity here because it's not quite as broad as NFL, not natural language processing it is somewhat constrained. that is a good part of it. The back part of it is that is highly technical. and so. you know some of the techniques you know you can have a fault tolerance in certain dimensions such as you know, misspellings lack of gambling and things like that. But as you have Heidi technical data, you cannot apply those principles because he could have misspelling the system may not be able to. Get, sometimes, and that's where you know I think. It's totally feasible to use. Resources to you know when you're dealing with. Tens of millions of patients and billions of detailed records. Using a I'd even identify those patterns of either. Inconsistent data or missing data it's also very powerful just to. kind of flag in identified. Areas that need to be focused on to lead to a better analysis. Greg Wait Be Hefty. Use that information somehow did is a belt of information that you know and so it just filtering into decision processes that the are really losing it. So hopefully getting improving in that dimension I've jumping to another paper bittersweet interesting. So it's entitled rates and predictors of using opioids in the Emergency Department Katrina Treat Mike Dean in Young Otto's and so so this is sort of a machine learning exercise you have gone through to locate you know coup is getting prescribed. OPIOIDS water the conditions for the Democrat not Nestle demographics but different different maybe age and things like that gender. and and then ask the question desert has some effect on addiction. In the long term rights. So that project To great example of team science though. We. Assembled a team of subject matter experts in neurology pain management. And Data Science and. The neurologist and pain management experts. Identified an intriguing question that we decided to pursue with data. In their question was. Based on anecdotal observation and so we thought it'd be interesting to see how well the data supported that. Observation is that. for youth and young adults Treated or admitted into the emergency. Department. With a migraine headache that. All too often they were treated with an opioid. And so we Use the same day to resource that we were discussing earlier. To explore that. Question. And using data from a hundred and eighty distinct emergency departments. We found that on average twenty, three percent of those youth and young adults were treated with. An opioid medication while they were in the emergency department. In general, it should be almost zero percent in general. There's really Better medications to us, four people presenting with a migraine. and. So this fits into obviously the OPIOID crisis it. it demonstrates the. Scenario describing that. You know using real world data. You can identify patterns of clinical behavior that. Don't match guideline. And the good news is that the? correctable and so through. Training and communication there's great opportunity to. To, manage this. Really. Striking. So fifteen thousand or so inevitably the encounters. And nearly a quarter of this encounters you say involved inoculate. and these are not just Misha and Congress right. It is not filtered down to migraine encounters. Okay. Okay. So these fifteen thousand just might in encounters might vein being repeating disease So once you. If you make a statement and. This or not Easter conditioning issue here. So you get your pain, you go to an emergency department and you get treated with an opioid you get quick tactical relief. From pain. auditing condition expect that in the next episode. So you can say we didn't pursue that particular question, but that is Definitely key part of. Managing the OPIOID crisis is that drug seeking behavior and so Part of our goal was to quantify that and use this as an opportunity to educate providers that. You really shouldn't be treating migraines with an opioid in there are better alternatives and. So we we felt that this was an important contribution to that national dialogue, but we didn't specifically pursue the question of whether the patients we analyzed. Within. Encounter show up Subsequently. With the same symptoms. Right right. Yeah you it develop into period when problematic patterns of drug use comedy. FEST MERGE THE PREVALENCE RATE OF OPIOID misuse estimated to be two to four percent and debts in each goofy just young adult drew from overdoses are rising. and. You say that literally prescribe IOS has been slumping loose future opioid misuse by thirty three percent. Betas Mehta say really huge number. I think just validates the importance of this of this work. Interesting mark. I don't know you exploded on data. Last the question if you look at the aggregate data, it'd be flying opioid. Misuse. what percentage of the total number. Actually started from. You know some sort of medical encounter has mike or some sort of. related encounter that could be completed otherwise was three a bit opioid. in that encounter documented resulted in that misuse. So what so If you look at the active misuse problem that we have today. do you have a sense of what percentage of that goal is actually started I? Think the exciting thing about this type of research is for everyone questioned that you pursue you have. You have ten new that you can pursue. We haven't. Delved into that specific area, but it's It's very ripe for further analysis and A considerable part of where I end my colleagues and our time as. We do this type of work to get an initial analysis published. And then You know in my leadership role I just WANNA. support people like my colleagues on this paper Mark Connelly Jennifer Bickel. in in using data to. Support their research into identify those follow. I mean, he tests policy implications. So it's sweet important work. and. If you find it direct relationship here than you have to ask you know from from a medical perspective what is right intervention? maybe is not just added of care just best practice but clearly should be the bay You know things should be looked at you say you're American Academy of Neurology has included avoidance of using opioid to treat gain one of stop top flight choosing wisely recommendations. For high-value duck in this gives Really evidence to to support that. The other thing that's really intriguing is this level of variation from site to site in. Some Sun facilities are very much aligned with the guidelines. Others are at the you know well, above twenty three percent. And that gives an opportunity for a really precision. conversations about you know, where does our organization stand on that spectrum? Yeah that's a that's an interesting avenue to right. So you know one could ask he says some sort of push sliced Intervention if we can fly goal of patients who who had gone an opioid sexually don't have an addiction problem. that as you know Anna, the kofoed does. if you can fly those type of patterns than you can think about. A customized within electronic health record systems. There's. The ability to provide decisions poor. There's certainly phenomena called pop up fatigue were physicians. You know they don't like having so many pop up windows but at the same time. It's Within the capability of an e e Hr to do that if then logic if patient has. migraine medication order equals opioid. encourage the provider to pause and reconsider that. Right, right and so this is supervised machine learning type analysis where so you have. you have number features that comes directly from each else. So each sex race ethnicity. insurance type. Encounter prostate suggest duration. time of the year and so on. and you have labeled data in this case I guess you have able tater because you would know if op- inscribed on trade. Okay and so are the two questions here. One is to ask the question given a new patient and those features. you could assign a probability that that patient will be prescribed will. Definitely. Impress the data from that predictive Minds. Right and then can you so that data definitely tell you if the patient is going to progress into some sort of an addiction issue. So. Earn Predicting Substance Abuse. So. Yeah. Yeah. Yeah. There's additional diagnosis codes that document. whether a patient has a history of substance abuse disorder. and. So it would be feasible to. Identify the with those diagnosis codes in than really look at their prior history. Of What other conditions were they treated for? What medications were they give in? to develop that model. One of the things in this case that helped with this study is that just in general, it's not advised get. So there are other things that are much more of a gray area. Or whether opioid is as useful, but in this case. The really not. Considered. To be helpful for migraines compared to other options and so that help us have a fairly clear cut scenario to do this work. Yeah. This this won't be the data like you say once you do something like this, you have been other things you could. You could stop asking. So unquestioned that that been to my mind as you know, how did they hugged the actually prescribing opioids? Is it the patient asking for it all so? Off that was another scoping thing with this project is focused on what happens within the emergency. Room. So it's it's. Really, medication order in administration that happens. In that emergency room setting. Whether or not the patient. was. Requesting that you know if they came in and said, this has worked for me before. Can I have it again? we don't have visibility to that. Right. Right. And so from a practical perspective So the the analysis that you did slightly ended up with the Family Clyde power we think it is. Compelling. Pretty compelling. So as as a new patient gets into e D either high. and what I mean by that probably is if there is a history of substance abuse property. the physician has really think twice about. The use of may be the well, and in this case, even without that history. Just because it's not considered to be an effective treatment. You know encouraging them to pause in that decision making. In this particular case is as effective as wall. Right. So looking forward. In if you think about both of these issues, one is the data quality data aggregation data standardized recent problem in the the right of Utah Systems have did that the talked about? And then if we can get to a level that we can look at cross a large data set. Beacon, ask. More. US specific questions, treatment. Optimum treatment type questions. subpoenaed. US The mark big think B be hunting. Certainly, the volume and variety of data that we're able to work with will be even greater I, think the. Opportunity To. Look, holistically at how upstream data capture. Effects Downstream data. Analysis. example I frequently give is if we have a Aggregate Data said we identify. Ten patients whose way in that data such shows up as being. Something that's completely infeasible. let's say they're documented is being. Fifty year old person who weighs two pounds. Clearly air. What's important is? Creating the process to communicate that back upstream. Because that clinical decision. Support. Many drug dosing things are evaluated using weight based logic and so. That same logic that's Evaluating the appropriateness of dosage. It's going to be running against an incorrect value in that may or may not always be visible. So I really am intrigued with that holistic opportunity. In it I am I remain just we have three or four additional papers coming out. About other examples where Provider behaviors not aligned with Best Practices and I'm just excited about you know when you compare that to how long it takes to develop a new drug or how long it takes to. To a really long term research. This research has the opportunity for a pretty quick turnaround on an effective intervention. A really that. Other so much that right. Providers. been taught in a no, but they're. Not always using that in practice and so to help them. Identify, those topics in just modifying behaviors is. In the scheme of things, it's a very straightforward way to improve. So. You know the entire spectrum from essentially getting the data. Right or cleaner like you know Missa mischaracterized or miss input data like wait or something like that. To to get. Better diagnosis better treatment modalities. policies there and from a femme perspective clearly inflammation therefore clinical trials. I was even thinking about drug interaction type. Inflammation. I haven't been involved in the former de for awhile but. Typically, this type of data doesn't get back into automatic processes that fast but I think that is all I know there's strong interest in Pharma in. Working with this type of data there a again looking at real world behavior. This is an excellent resource for off label medication use at. you know where Pharma's Always interested in repurposing existing medications the. Regulatory Processes, much more straightforward for that because the safety is already been. Evaluated and so. The. Significant Opportunity With this, there's also just exciting. Patterns of you know. What are those unrecognised correlations? That's where the machine learning opportunities are really exciting where. You know we're not always asking the right question. And the data can show us what we should be. Yeah exactly. So if the machine a sort of red flags something or create hypotheses. that Cubans have missed sometimes, those types of things are extremely powerful. because maybe that sometimes it's countering tutor. and so we all look at data with an Incan bias. The beauty of machines that at least on the surface began deploy Michigan. This volume of data. Techniques like machine deep learning can recognize those subtle but consistent associations. Wait quite. Excellent. Idea this has been great mark Thanks so much time with me. I enjoyed it very much. Thank you. But

Policy Technology Economics Science Gill Eappen Mike Yesterday Dr Mark Hoffman Children's Mussa Hospital Turner Electronic Certner Migraine Inflammation Federated Networks Stan Day Squatty Michio Kato University Of Minnesota Makita GIL Federated Kansas City
Dr. Mark Hoffman, Research Associate Professor at the University of Missouri, Kansas City - burst 01

Scientific Sense

44:57 min | 2 years ago

Dr. Mark Hoffman, Research Associate Professor at the University of Missouri, Kansas City - burst 01

"Welcome to the site of accents podcast. Where we explore emerging ideas from signs, policy economics, and technology. My name is Gill eappen. We talk with woods leading academics and experts about the recent research or generally of topical interest. Scientific senses at unstructured conversation with no agenda or preparation. Be Color a wide variety of domains red new discoveries are made. and New Technologies are developed on a daily basis. The most interested in how new Ideas Affect Society? And, help educate the world how to pursue rewarding and enjoyable life rooted in signs logic at inflammation. V seek knowledge without boundaries or constraints and provide unaided content of conversations bit researchers and leaders who low what they do. A companion blog to this podcast can be found at scientific sense dot com. And displayed guest is available on over a dozen platforms and directly at scientific sense. Dot? Net. If you have suggestions for topics, guests at other ideas. Please send up to info at scientific sense dot com. And I can be reached at Gil at eappen Dot Info. Mike yesterday's Dr Mark Hoffman, who is a research associate professor in the University of Minnesota Against City. He is also chief research inflammation officer in the children's Mussa hospital in Kansas City. Kiss research interests include health data delayed indication sharing initialisation Boca Mark. Thank you for inviting me. Absolutely. So I start with one of your papers Kato you need the use by our system implementation in defy date data resource from hundred known athlete off my seasons. So Michio inflicted. Data aggregated for marketable sources provide an important resource for my medical research including digital feel typing. On. Like. Todd beat to from a single organization. Guitar data introduces a number of analysis challengers. So. So you've worked with some augmentation log and in almost all cases be used. Data coming from that single macy's listen primary care behavioral. Or specialty hospitals and I always wondered you know wouldn't be nice. Get a data set. That sort of abrogates data from the radio on-ice. Asians but a lot of different challenges around that. So you wanted to talk a bit about that. I'd be happy to the resource that we've worked with. Is primarily a called health fax data resource. It's been in operation for almost twenty years. And the the the model is that organizations who are. Using these Turner Electronic. Health. Record. Enter into an agreement was turner they agreed to provide data rights to sern are. The identifies the date of affords aggregated into this resource. And certner provides data mapping, which is really critical to this type of work. It also the aggregate the data. And for the past probably six years. Then, they provide the full data set to especially academic contributors who want to do research with that resource. And I've been on both sides of that equation Lead that group during my career there, and then now I have the opportunity to really focus research on that type of data. So before we get into the details smog so e Itar Systems. So this is. Essentially patient records. So he gets dated like demographics out family history, surgical history hats, medications, lab solves it could have physician nodes no snow. So it's it's a combination of a variety of different types of data, right? A couple of things on the examples you gave it includes demographics. Discreet Laboratory results Medication orders. Many vitals so If access the blood pressure and pulse data. It does not include text notes because those can't be. Automatically identified consistently. So. We don't have access currently to TEX notes. Out of an abundance of caution. That his Hobby Stephen, physician writes something down they could use names they could use inflammation that could then point back to their. Patients Makita Perspective been the data's aggregated, the primary issue shoe that date has completely the identified, right? Correct. So. So yeah. So the data that we receive there's eighteen identifiers. Hip requires be removed from data. And those include obvious things like name address email addresses are another example One of the. Things. That is also part of the benefit of working with this particular resource. The. Dates of clinical service are not allowed to be provided under hip. White is done with this resource that allows us to still have a longitudinal view is. For any given patient in the data set the dates are shifted by A. Consistent. Pattern that for any given patient it can be. One two three four five weeks forward or one, two, three, four or five weeks backward. But that preserves things like day of the week effect. So for example, you see -nificant increase in emergency department encounters over weekends and you don't WanNa lose. Visibility to that. but it also allows us to receive. Very, granular early time stamped events in so. We can gain visibility into the time that a blood specimen was collected, and then the time that the result was reported back. And so we're able to do very detailed analyses with this type of resource. Right right and I don't know the audience our market is fragmented. Tau himself e Amorebieta providers out there. and so two issues. One is sort of. Standardization as to how these databases are designed and structured and others even that standardization that the actual collection of the data. In itself is not standardized played. So vk CAV vk potentially lot inability coming from different systems. Correct and that's part of what the paper that you mentioned Evaluates so. Often, night you out in the field in conferences you hear. Comparisons kind of lumping all organizations using one. Vendor lumping all using another together but as you get closer to it, you quickly learn that. It's not even clear. It's within those. Vendor markets. There's variation from organization to organization in how they use the e Hr and so. Because the identities of the. Contributing organizations are blinded to those of us who work with the data. We have to be creative about how we. Infer those implementation details, and so with this paper, we describe a couple of methods that We think move things forward towards that goal. Yes. So I'm not really familiar with that. So you mentioned a couple of things here. One is the the merge network. So this initiative including electric medical records and genomics network and pc off net the national patient, centered clinical research network support. Decentralized analyses that goes disparate systems by distributing standardized quotas to site. So this is a situation where you have multiple systems sort of. Communicating with each other and this net folks at allowing to sort of quickly them In some standardized fashion. So In this type of technology, there's janitorial core models. One is the. Federated or distributed model, the other is a centralized data aggregation. So there are examples including those that are mentioned in the paper where. Queries are pushed to the organization and. They need to do significant work upfront to ensure that there are standardizing their terminologies the same way. And once they do that upfront work than they're able to perform the types of queries that are distributed through those. Federated Networks. With. Okay. So that just one click on so that the police have standardized. So all on the at Josh site, then they have like some sort of a plan slater from from Stan Day squatty do all the data structure. And in many cases, they work through an intermediate technology. that would be. In general, consider it like a data warehouse. And so the queries are running against the production electric. Health record. That has all kinds of implications on patient care where you don't want to slow down performance. By using these intermediaries They can receive queries and then Follow that mapping has occurred. Than, they're able to to run those distributed queries. Okay. And the other model is You know. You say the g through the medical quality, improvement consortium and sooner to the health facts initiative. So this says in Sodas case, for example, in swags. This is essentially picking up data from the right deals, clients and Dan standardizing and centralizing data in a single database is that that is correct. One benefit of that model is that Organizations who for example, may not be academic and don't have the. Resources to do that data mapping themselves by handing out over that task over to the vendor you get a broader diversity of the types of organizations so you can have. A safety net hospitals you can have. Critical access rural hospitals, and other venues of care that are probably under represented in some of those. More academically driven models. And clearly the focus on healthcare about I would imagine applications in pharmaceutical out indeed to right I. Don't know if it s use and bad direction there has been some were performed with these data resources to. Characterize different aspects of medications, and so it does have utility in value. In a variety of. Analytical contexts. I was thinking about you know a lot of randomized clinical trials going on into Kuwait context and One of the issues of dispatch seem development toils that are going on that one could argue the population there are not really well to percents. it may be number by Auditees, men, people that deputy existing conditions. and. So he will serve at my come out of facedly trial. granted might work for the population. Tried it minority have sufficient? more largely. So I wanted this type of well I guess we don't really have an ID there right. So clearly, you don't know who these people are but they could be some clustering type analysis that might be interesting weight from It's very useful for Health Services Research and for outcomes research for you know what I characterize digital phenotype being. they can then guide. More, more formal research. you know you can use this type of resource to. Make sure. You're asking a useful question and make sure that there's likely to be. Enough patients who qualify for given study. Maybe you're working on a clinical trial in your casting your net to narrow you can. Determine that with this type of data resource. And is the eight tiff date who has access to it typically. So for this data resource on, it's through the vendor so. You need to have some level of footprint with them. which is the case with our organization. They're definitely a broadening their strategies. So they're. Gaining access into health systems that aren't exclusively using their electronic health records so. It's exciting to be a part of that that process. and to again work with them to. Analyze the data. I think. To the example you gave a formal randomized trials. In key part of what were growing our research to focus on is because this is real world data. You learn what's happening in practice whether or not it's well aligned with guidelines or formal protocols. And doing that there's many opportunities for near-term interventions that can improve health outcomes simply by. Identifying where providers may be deviating more from. Best Practices in than taking steps through training and education to kind of get them back towards those best practices. This data is a fresh on a daily basis. It's not. It's because it's so large and bulky? Typically we've received it on a quarterly basis in since it's retrospective analysis that's not been a major barrier. But. mechanistically, on onto soon aside is data getting sort of picked up from this system that it's harvested every day and then it's aggregated bundled and distributed on A. On a different timescale. Okay okay. So. From again, going to the, it's our system designed issue and implementation You say many HR systems comprised of more news at specific clinical processes or unit such as Pharmacy Laboratory or surgery talked about that. But then then people implement them this of fashion right they they implement modules by that can be a factor or sometimes they may want. One vendor for their primary electronic health record, but another vendor for their laboratory system. and so that's where you don't see a hundred percent usage of every module and every organization. And detailed number of different you know sort of noise creating issues in data one. This is icy speech over from ICT denied ten. and I don't know history of this but this was supposed to be speech with sometime in twenty fifteen. That's correct. So there is A. You know. There's a date in October of Twenty fifteen where most organizations were expected to have completed that transition. When I see with researchers who aren't as familiar with the you know the whole policy landscape around `electronic health records that? you can imagine researchers who assumed that all data before that date in October is is nine and all data after that date would be icy the ten. While we demonstrate in this paper, is that that transition was not Nearly, that clean and it was a much more, you know there are some organizations who just It the bullet and completed in twenty fourteen, and there are other organizations that were still lagging. In. Two Thousand Sixteen. Potentially because they weren't as exposed to those incentives in other things that you know stipulated the transition so. Part of why were demonstrating with that particular part of that work was that. you know these transitions aren't always abrupt. Yeah and and and so that is one issue and then you know a lot of consistency inconsistency issues fade. So we see that in in single systems and one of the items note here as you know if you think about the disposition code for death. you could have a right your race supercenter, right? It's a death expire expedite at home hospice, and so on. if this is a problem for a single system, but then many think about aggregating data from multiple sources this this problem sort of increased exponentially. Absolutely. So one of the challenges with documenting and and finding where you know if a patient has A deceased that. There's just multiple places to put that documentation in the clinical record. The Location in the record that. We have found to be the most consistent is what's called discharge disposition. By as we show in that analysis, that field is not always used document that and so if you're doing outcomes research and one of your key. Outcome metrics is death. And there are organizations that. Aren't documenting death in a place that successful. You should filter those out of your analysis before moving forward. And so part of what we wanted to promote is the realization that. That's the type of consideration that needs to be made The four. Publishing. Your data about an outcome metrics like death that. You're not. If you're never gonNA see that outcome it doesn't mean that people are. Dying in that particular facility, it just means it's not documented in the place that successful. Right. Yeah. So you know you on your expedience. Unique Position Mark because you you look at it from the from the vendor's perspective you're in an academic setting you're also in practice in a hospital. What's your sense of these things improving the on a track of getting getting this more standardize or it's camping in the other direction I think in general there is improvement I think The. Over the past eleven years through various federal mandates, including meaningful use and so forth. Those of all incentive organizations to utilize. Standard terminologies more consistently than was the case beforehand. I think there's still plenty of room for improvement and You know it's it's a journey, not a destination, but I think things have improved substantially. I was wondering there could be some applications of artificial intelligence here to In a clearly TATECO systems and you'd like the most them pity human resource intensive Yvonne to get it completely right. So one question would be you know, could be actually used a Dick needs to get it maybe ninety nine percent white. And that the human deal with exceptions I definitely think that that's an exciting direction that You want those a algorithms to be trained with good data, and that's a big part of what's motivated us to. Put this focus on data quality and Understanding these strange nuances that are underpinning that date has so that. As we move towards a in machine learning and so forth. We have a high level of confidence in the data that's training those algorithms. Right. Yeah. I think that a huge opportunity here because it's not quite as broad as NFL, not natural language processing it is somewhat constrained. that is a good part of it. The back part of it is that is highly technical. and so. you know some of the techniques you know you can have a fault tolerance in certain dimensions such as you know, misspellings lack of gambling and things like that. But as you have Heidi technical data, you cannot apply those principles because he could have misspelling the system may not be able to. Get, sometimes, and that's where you know I think. It's totally feasible to use. Resources to you know when you're dealing with. Tens of millions of patients and billions of detailed records. Using a I'd even identify those patterns of either. Inconsistent data or missing data it's also very powerful just to. kind of flag in identified. Areas that need to be focused on to lead to a better analysis. Greg Wait Be Hefty. Use that information somehow did is a belt of information that you know and so it just filtering into decision processes that the are really losing it. So hopefully getting improving in that dimension I've jumping to another paper bittersweet interesting. So it's entitled rates and predictors of using opioids in the Emergency Department Katrina Treat Mike Dean in Young Otto's and so so this is sort of a machine learning exercise you have gone through to locate you know coup is getting prescribed. OPIOIDS water the conditions for the Democrat not Nestle demographics but different different maybe age and things like that gender. and and then ask the question desert has some effect on addiction. In the long term rights. So that project To great example of team science though. We. Assembled a team of subject matter experts in neurology pain management. And Data Science and. The neurologist and pain management experts. Identified an intriguing question that we decided to pursue with data. In their question was. Based on anecdotal observation and so we thought it'd be interesting to see how well the data supported that. Observation is that. for youth and young adults Treated or admitted into the emergency. Department. With a migraine headache that. All too often they were treated with an opioid. And so we Use the same day to resource that we were discussing earlier. To explore that. Question. And using data from a hundred and eighty distinct emergency departments. We found that on average twenty, three percent of those youth and young adults were treated with. An opioid medication while they were in the emergency department. In general, it should be almost zero percent in general. There's really Better medications to us, four people presenting with a migraine. and. So this fits into obviously the OPIOID crisis it. it demonstrates the. Scenario describing that. You know using real world data. You can identify patterns of clinical behavior that. Don't match guideline. And the good news is that the? correctable and so through. Training and communication there's great opportunity to. To, manage this. Really. Striking. So fifteen thousand or so inevitably the encounters. And nearly a quarter of this encounters you say involved inoculate. and these are not just Misha and Congress right. It is not filtered down to migraine encounters. Okay. Okay. So these fifteen thousand just might in encounters might vein being repeating disease So once you. If you make a statement and. This or not Easter conditioning issue here. So you get your pain, you go to an emergency department and you get treated with an opioid you get quick tactical relief. From pain. auditing condition expect that in the next episode. So you can say we didn't pursue that particular question, but that is Definitely key part of. Managing the OPIOID crisis is that drug seeking behavior and so Part of our goal was to quantify that and use this as an opportunity to educate providers that. You really shouldn't be treating migraines with an opioid in there are better alternatives and. So we we felt that this was an important contribution to that national dialogue, but we didn't specifically pursue the question of whether the patients we analyzed. Within. Encounter show up Subsequently. With the same symptoms. Right right. Yeah you it develop into period when problematic patterns of drug use comedy. FEST MERGE THE PREVALENCE RATE OF OPIOID misuse estimated to be two to four percent and debts in each goofy just young adult drew from overdoses are rising. and. You say that literally prescribe IOS has been slumping loose future opioid misuse by thirty three percent. Betas Mehta say really huge number. I think just validates the importance of this of this work. Interesting mark. I don't know you exploded on data. Last the question if you look at the aggregate data, it'd be flying opioid. Misuse. what percentage of the total number. Actually started from. You know some sort of medical encounter has mike or some sort of. related encounter that could be completed otherwise was three a bit opioid. in that encounter documented resulted in that misuse. So what so If you look at the active misuse problem that we have today. do you have a sense of what percentage of that goal is actually started I? Think the exciting thing about this type of research is for everyone questioned that you pursue you have. You have ten new that you can pursue. We haven't. Delved into that specific area, but it's It's very ripe for further analysis and A considerable part of where I end my colleagues and our time as. We do this type of work to get an initial analysis published. And then You know in my leadership role I just WANNA. support people like my colleagues on this paper Mark Connelly Jennifer Bickel. in in using data to. Support their research into identify those follow. I mean, he tests policy implications. So it's sweet important work. and. If you find it direct relationship here than you have to ask you know from from a medical perspective what is right intervention? maybe is not just added of care just best practice but clearly should be the bay You know things should be looked at you say you're American Academy of Neurology has included avoidance of using opioid to treat gain one of stop top flight choosing wisely recommendations. For high-value duck in this gives Really evidence to to support that. The other thing that's really intriguing is this level of variation from site to site in. Some Sun facilities are very much aligned with the guidelines. Others are at the you know well, above twenty three percent. And that gives an opportunity for a really precision. conversations about you know, where does our organization stand on that spectrum? Yeah that's a that's an interesting avenue to right. So you know one could ask he says some sort of push sliced Intervention if we can fly goal of patients who who had gone an opioid sexually don't have an addiction problem. that as you know Anna, the kofoed does. if you can fly those type of patterns than you can think about. A customized within electronic health record systems. There's. The ability to provide decisions poor. There's certainly phenomena called pop up fatigue were physicians. You know they don't like having so many pop up windows but at the same time. It's Within the capability of an e e Hr to do that if then logic if patient has. migraine medication order equals opioid. encourage the provider to pause and reconsider that. Right, right and so this is supervised machine learning type analysis where so you have. you have number features that comes directly from each else. So each sex race ethnicity. insurance type. Encounter prostate suggest duration. time of the year and so on. and you have labeled data in this case I guess you have able tater because you would know if op- inscribed on trade. Okay and so are the two questions here. One is to ask the question given a new patient and those features. you could assign a probability that that patient will be prescribed will. Definitely. Impress the data from that predictive Minds. Right and then can you so that data definitely tell you if the patient is going to progress into some sort of an addiction issue. So. Earn Predicting Substance Abuse. So. Yeah. Yeah. Yeah. There's additional diagnosis codes that document. whether a patient has a history of substance abuse disorder. and. So it would be feasible to. Identify the with those diagnosis codes in than really look at their prior history. Of What other conditions were they treated for? What medications were they give in? to develop that model. One of the things in this case that helped with this study is that just in general, it's not advised get. So there are other things that are much more of a gray area. Or whether opioid is as useful, but in this case. The really not. Considered. To be helpful for migraines compared to other options and so that help us have a fairly clear cut scenario to do this work. Yeah. This this won't be the data like you say once you do something like this, you have been other things you could. You could stop asking. So unquestioned that that been to my mind as you know, how did they hugged the actually prescribing opioids? Is it the patient asking for it all so? Off that was another scoping thing with this project is focused on what happens within the emergency. Room. So it's it's. Really, medication order in administration that happens. In that emergency room setting. Whether or not the patient. was. Requesting that you know if they came in and said, this has worked for me before. Can I have it again? we don't have visibility to that. Right. Right. And so from a practical perspective So the the analysis that you did slightly ended up with the Family Clyde power we think it is. Compelling. Pretty compelling. So as as a new patient gets into e D either high. and what I mean by that probably is if there is a history of substance abuse property. the physician has really think twice about. The use of may be the well, and in this case, even without that history. Just because it's not considered to be an effective treatment. You know encouraging them to pause in that decision making. In this particular case is as effective as wall. Right. So looking forward. In if you think about both of these issues, one is the data quality data aggregation data standardized recent problem in the the right of Utah Systems have did that the talked about? And then if we can get to a level that we can look at cross a large data set. Beacon, ask. More. US specific questions, treatment. Optimum treatment type questions. subpoenaed. US The mark big think B be hunting. Certainly, the volume and variety of data that we're able to work with will be even greater I, think the. Opportunity To. Look, holistically at how upstream data capture. Effects Downstream data. Analysis. example I frequently give is if we have a Aggregate Data said we identify. Ten patients whose way in that data such shows up as being. Something that's completely infeasible. let's say they're documented is being. Fifty year old person who weighs two pounds. Clearly air. What's important is? Creating the process to communicate that back upstream. Because that clinical decision. Support. Many drug dosing things are evaluated using weight based logic and so. That same logic that's Evaluating the appropriateness of dosage. It's going to be running against an incorrect value in that may or may not always be visible. So I really am intrigued with that holistic opportunity. In it I am I remain just we have three or four additional papers coming out. About other examples where Provider behaviors not aligned with Best Practices and I'm just excited about you know when you compare that to how long it takes to develop a new drug or how long it takes to. To a really long term research. This research has the opportunity for a pretty quick turnaround on an effective intervention. A really that. Other so much that right. Providers. been taught in a no, but they're. Not always using that in practice and so to help them. Identify, those topics in just modifying behaviors is. In the scheme of things, it's a very straightforward way to improve. So. You know the entire spectrum from essentially getting the data. Right or cleaner like you know Missa mischaracterized or miss input data like wait or something like that. To to get. Better diagnosis better treatment modalities. policies there and from a femme perspective clearly inflammation therefore clinical trials. I was even thinking about drug interaction type. Inflammation. I haven't been involved in the former de for awhile but. Typically, this type of data doesn't get back into automatic processes that fast but I think that is all I know there's strong interest in Pharma in. Working with this type of data there a again looking at real world behavior. This is an excellent resource for off label medication use at. you know where Pharma's Always interested in repurposing existing medications the. Regulatory Processes, much more straightforward for that because the safety is already been. Evaluated and so. The. Significant Opportunity With this, there's also just exciting. Patterns of you know. What are those unrecognised correlations? That's where the machine learning opportunities are really exciting where. You know we're not always asking the right question. And the data can show us what we should be. Yeah exactly. So if the machine a sort of red flags something or create hypotheses. that Cubans have missed sometimes, those types of things are extremely powerful. because maybe that sometimes it's countering tutor. and so we all look at data with an Incan bias. The beauty of machines that at least on the surface began deploy Michigan. This volume of data. Techniques like machine deep learning can recognize those subtle but consistent associations. Wait quite. Excellent. Idea this has been great mark Thanks so much time with me. I enjoyed it very much. Thank you. But

Policy Technology Economics Science Gill Eappen Mike Yesterday Dr Mark Hoffman Children's Mussa Hospital Turner Electronic Certner Migraine Inflammation Federated Networks Stan Day Squatty Michio Kato University Of Minnesota Makita GIL Federated Kansas City
How to End Negative Self-Talk

The Chalene Show

07:04 min | 3 years ago

How to End Negative Self-Talk

"I'm going to give you five very very realistic things that you can do to literally change the cycle of negative thinking. I know you've heard podcasts on this before. And you've maybe read read articles or you've heard some expert talk about you know how to change negative self talk in some of the tips and suggestions that people give you are so corny and they sound great but like freaking. No one does this so I spent some time talking to people who by their own. Admission were once very negative like really spoke negatively in their head to themselves like they trash talked themselves and I spent some time asking like okay. So where did you do like. How did you change this and do any of these other tips that we've heard like make a list of all the positive qualities and tracy you have do those things work and while most people? I talked doc you said Yeah they work. I just don't really think I did those things and I said all right. Well let me take inventory of what you did do. That's realistic. Listrik our help people with this number four. I go much further. The first thing I should do for you is help you figure out if in fact this is good episode for you to listen to. I don't want to waste your time so if you're dealing with this and you're even just slightly aware that you do sometimes and you want to change it will then you should listen but even more motivating than that I think is the results of five. Psychological studies recently conducted the demonstrated. Get at this that those people who have a consistent pattern of negative self-talk have a direct negative correlation with gold mastery in other words. The Higher People reported that they are the more highly people think of themselves a more highly people speak to themselves in their head head. The more likely those people are to actually accomplish things they set out to do. And you've a lot of things you WANNA do your life to look a sern way. I know you do so if that's important. You can't figure out like okay. Why isn't it happening? It's not that the world's conspiring against you in May have a lot to do with this negative criticism at self criticism that we all can get into the habit of in it's sometimes lies dormant. You don't even realize you're doing it because you know you're a positive person see. Here's the thing positive people right people who are like always in a good mood they always you know. Say Nice things Dave and see the good in other people. They're not doom. They're just like really positive people. If that's that's you you don't often admit they you're mean or negative or really hard on yourself because you look positive person so today today. That's one of the first things I'm GonNa ask you to do. In fact that step one. Let's get right to this step one. Is You gotta catch yourself. You can't fix something dumping the you don't know is broke like one of the scariest traits to me is when someone doesn't know they have a problem. That's a problem. We don't know you have a problem. That's that's the problem. I think I talked about this in another episode where I think one of the most enduring positive traits and qualities that people have is when they own their shortcomings and that doesn't mean he beat yourself up over. It means that you realize you know what I missed the mark there or you know what. That's my bad. You know what this is something I I have to work on with me and so that's really important. If you say that you are a person who's into growth if you truly are into growth you have to realize you have to identify by the areas where you need to grow. He got to catch yourself in this. So that's step one he's got to catch yourself and the reason why we do this why we can trash talk ourselves or even just have quick negative thought you know. Sometimes it's fleeting like you mess up or you miss a turn. He make a mistake which we all do. And you just go dang it or you can just say in your head. Why are you so stupid? Why are you paying attention on my? You're such a loser always late. These little tiny quick voices that we don't even realize sometimes because it's not actually a voice. I mean sometimes I'm just saying these things out loud that's like a whole `nother level but I think the majority of us is just a quick thought. So we dismiss it not as being negative self-talk because we're like. Oh I just had this thought but that thought is in fact you trash talking you and the only way we ever change only way we ever get better is when we feel good. Now you let me know the last time you felt good when someone was name calling you trash-talking you saying mean or cruel things or criticizing you and that never makes you feel good ever ever never ever. So what makes us think that it serves us right like you want to change you. Want to be a better person person so going about it by criticizing yourself is as foolish as it would be to criticize your child and think that they're going to turn out better because of it although speaking of children in childhoods I think that's where some of this comes from especially those of us who really struggle with it. Like if that's something that you are always always hard on yourself. It's often because that self criticism was or that criticism. I should say as something you experience as a child like a parent who is thought that they were being helpful by pointing out the things that you were doing wrong. Thought that their feedback would allow you to correct course and be more perfect individual Wohl which is often just from their own feelings of inadequacy but it just keeps getting passed down and passed down and pass down. And you know you didn't love it and you know it didn't make you. I feel very loved or lovable but yet it became a habit you kept hearing it and not that voice gets stuck in your head and it makes a little like a groove in your brain brain and you just keep playing it on loop now. You don't even realize it's not even the tape of your voice. It's playing in your head. It's like a recording of someone else's voice something someone else said and it's just repeating in your head so most of the time when we start thinking these thoughts in our own head. It's because somehow we believe leave that if we think these thoughts it's going to foster self-improvement we believe in some way in some manner that if we think these thoughts that we will correct ourselves and we'll want to obey these thoughts but honestly the opposite is true. It's only when we're kind and loving to ourselves. It's only when we give ourselves grace and see the best ourselves and believe the best inner selves that we truly truly have the ability to be

Dave Wohl
Getting bisphenol A out of food containers

Science Magazine Podcast

12:56 min | 3 years ago

Getting bisphenol A out of food containers

"I up in our Green Chemistry special edition of the podcast. We have contributing correspondent. Warren Cornwall here with the story about finding a replacement for the common can lining chemical this funeral a or commonly known as EPA these days high. Warren you start with this fulcrum this point where the tab of a can of soda attached to the body of the Cana Soda. Why is that a good place to start the story? I never knew how amazing the science and engineering around making I can was started reporting this story in this particular case. Ace this point where the pull tab is. Attached to the top of an aluminum drink can is subject to these huge stresses. You have to imagine that the inside of this whole can is covered in this. Thin layer of plastic can't break in order to attach this poll tab to the top of the can Dan basically after pound with a machine on the can top to create this little bump and then the pull tab sits on the bump and then you mash that bump flat because the what is saying. It's the most difficult fabrication in the whole universe. But I think he says in their whole universe okay that makes you and the whole universe the people at Sern would appreciate that but in the universe can fabrication for linings. That's their crux. We're GONNA talk about the lighting's the special liner inside of these cans usually contains. BPA OR A. What exactly is the purpose can't ends contained all kinds of material that can potentially be corrosive all kinds of acidic drinks? I don't know if you remember from elementary school. Well experiment where one of your teachers would put a nail inside of a jar with coq a few days later. It'll be gone so yeah stuff is corrosive And apparently the kinds of stuff that we're putting into cans now is even more corrosive than it used to be. All of these kinds of fancy craft beverages energy. He drinks so they don't want to eat holes in the cans and then the flip side of that. Is that if you've ever put a piece of aluminum in your mouth. It tastes weird and you don't I don't want that flavor to go into the food or drinks so the properties a can lining material have our resists corrosion. Obviously obviously what other things are important. Doesn't create any weird flavors of its own. Ideally it's inert so it doesn't react with anything It's inside the can in a perfect doc world. It's not at all toxic. It's still a benign. It has to be as cheap as possible and it has to go on the cans really easily really quickly quickly because they're cranking out cans at a rate of two thousand a minute so BPA. Which I think most people have heard of at this point because of concerns about its effect on health? Health checks these boxes except for the health one. What are the health concerns when it comes to? BPA well the main concern is that it can mimic estrogen when the body encounters BPA it can bind with estrogen receptors. Enough that the body. Can I think that it's binding with estrogen. There's a lot of debate going on about how much of a health risk is really posed by. EPA in the levels that it's founded pardon people's bodies the FDA still allows it to be used in most food related containers with the exception of baby bottles and sippy cups so the is said that the science suggests that it's not really a problem in other settings said the chemical industry and other industry groups have taken that got same message but you have consumer groups environmental groups and some university researchers that have done work suggesting that it can be problematic one of the stats. You mentioned in your story. About how more than ninety percent of people who live in the US have EPA in their urine. We pretty much that'd be a and US And some governments non. US governments have also decided to ban PBA right. You know the only one that I know of its flea abandoned his France right and you know one of the thing. I should know just going back to a comment that you made earlier about. BPA and cans. I've been told that for food cans in the United States about ninety percent of it is non. BPA At this point so food cans like peas and corn drink cans to or know for aluminum. EMINEM drink cans. It's about fifty fifty. Okay they've cut way down on this but about how much. BPA is still out there. Do you know how many cans with US liner are made. Every year they are every month. Yeah estimates are worldwide that we crank out about four hundred fifty billion with a B. Tans every year yeah three hundred hundred and fifty billion of those are aluminum drink cans the other one. Hundred billion are food cans some not small percentage are lied with. That's right you talked to. Scientists at a company called Thou spar that came up with a a new alternative a few years ago and a very unusual way. How did they get involved? Vow Spar in two thousand seventeen was purchased by Sherwin Williams. Okay this company had a business. Making chemical can linings and and one of the significant parts of that business for them was making BP based linings but they and other manufacturers were seeing the pushback from consumers and some governments guest EPA and so they were looking for alternatives. What they were finding is that? The alternatives had drawbacks right. Some of them were for more expensive or didn't hold up as well or did perform in some way that Kanye manufacturers wanted or for if they were trying to find a replacement in the same family of chemicals as BPA that family abyss females. There was concern sern that those chemicals were going to have some of the same health related concerns that beep at everybody was pushing to find a replacement because the biggest fear fear is that governments are going to step in and say no more. BPA Right. I mean the thing that's interesting to me is that they decided to go for it. Because you can imagine a company saying Oh man that could be a really expensive yet and there's a guy in the story who kind of figures in the Tom Tom Mallon and he's interesting because he's very much industry insider he's worked at. This company is whole life but he from the outset said look. We're going to have to go about this a different way. We're GONNA have to reach out to people outside the industry people outside. The industry don't necessarily trust US anymore when it comes to things like BPA safety so we're going to have to think about this a different way. People tell me that this is really unusual. This is a real culture shift. So what did they do to narrow the pool of chemicals out there to replace. VP aligning so they bring in a chemist from the outside who has experience in the pharmaceutical industry and the pesticide industry. So basically he had this long list of bisque dolls. That might work as can liners and the first green that he did was running them through a computer program that would see whether they were likely to fit in the estrogen receptor or not and then the ones that came out as potentially a non estrogens they then sent off for a series of slab screenings. The basic one was a yeast screening where these yeast cells have been engineered to glow when they're exposed to estrogen compound. At that point they have to do more tests to find out if these chemicals are also going to work well as a can liner they finally narrow it down to one candidate. Wow it's called Tetra. Methyl BIS Funeral F or T. Mbps they narrowed it down to this one mechanical and it had passed them basic tests when it came to its ability to affect estrogen receptors. And it was able to stand up to The harsh environment of inside a can. This is where they turn to. Basically they turned to their critics and said you tell us that this isn't safe to wasn't said they were challenging them the way they described it to me as they were coming to scientists and saying we want to build a better molecule for this. What should we do to make sure that it's actually going to be safer? Yeah they posed this question to environmental and public health advocacy groups and they impose that same question to researchers who have done a lot of science studying BPA and they actually took the chemical to their labs and tested faceted out and a bunch of different ways. That's right they set up the payment in a way that the scientists said they kept their independence so so the best example is a endocrinologist at Tufts. Anna Soto has done a lot of work on. EPA and its effect on in breast tissue the company made a contribution to tufts with no strings attached so it was not hurt to her lab specifically and then she came to tufts and said give me money for my research search and she found that there weren't Astra genetic effects from this alternative to be. Yes right she didn't find any evidence that was stragetic And then the secondary element that that was interesting is that she didn't find evidence that the can lining was leaching any of its T. M. B. PF contents into into the liquids. This letting him ICAL has been approved by the FDA for use in food product container. So it's already on the market. It's already something that people have probably encountered in their day to day life. The company has their chemical has been used to line twenty two billion cans since twenty seventeen nine. Wow so a lot of cans but a small fraction of the overall universal cans right going back to the safety testing that we talked about. I think it sounds is wise to approach people who have built up the skills to test for Indian disruption in their labs but is there ever a way to know if something is safe. It's kind of like the bigger question if the FDA's testing aren't necessarily rigorous enough. What should be happening to show that a chemical a safe to go sit next to food that might absorb it? That's an open question. Part of what was interesting to me about. This story. Is that when val spar went looking for an alternative Bernard route for testing their product. There was no road map for them to follow And that's still the case. They can't point to a battery battery of tests and say look. We have jumped through these hoops that everybody has agreed are the hoops that we should jump through did it successfully and therefore we can declare our chemical to be a gold star. Green label chemical. Is there a movement to codify. Something is an endocrine disruptor if it does this and if it doesn't do these things these five things or these ten things and it's not an endocrine disruptor. There are various efforts to come up with better more more rigorous more detailed ways of screening chemicals for possible construction. Regulators would argue that they currently have tools for declaring declaring whether a chemical is an endocrine disruptor or not and they're working on improving them so it's not like they're saying that their ways the the only way and there's no improvement to be done right our other companies going to follow this model of looking for chemicals to replace something that people have a lot of questions sweat and then turning to people outside industry to test it for health concerns. I don't know I mean I've talked to some people who've said that they think it it's a promising model. They think that the experience of Alice bars had suggested a company can do it successfully. But you know I've talked to other people who've said that there are companies who are working to develop greener safer chemicals but have really chosen to do it internally and keep it to themselves salves partly because there is a concern that if you say that you're trying to replace one of your chemicals with something safer you're bringing attention into concerns about safety of the clear curly us. Well thank you so much more and I sure thank you Sarah. Warren Cornwall is a contributing correspondent piece in Washington State. You can find a link to his article and the rest of the special section on chemicals. Tomorrow's Earth at science mag dot org slash podcast

EPA United States Warren Cornwall FDA BPA Green Chemistry Tufts Cana Soda Sern DAN France Vow Spar PBA Tom Tom Mallon Eminem B. Tans VP Kanye
Could There Be a Fifth Fundamental Force?

BrainStuff

06:38 min | 3 years ago

Could There Be a Fifth Fundamental Force?

"The four fundamental forces are the most important quartet in science so far is anyone's been able to prove the universe is governed by these forces forces gravity electromagnetism the strong force and the weak force. But maybe this foursome isn't alone in two thousand fifteen. A Hungarian and team led by physicist Attila. Credit Hawkeye reportedly discovered new evidence for a fifth fundamental force. Something previously unknown to science. The the group uploaded another paper about the subject to archive a research database in October of two thousand nineteen while many scientists are skeptical about these findings. The research search does give us an occasion to talk about the major forces that we all take for granted the Fab four fundamental forces are irreducible meaning. They can't be broken down into other more basic forces. These are the core phenomena behind every other known type of physical interaction. For example friction tension and elasticity busy are all derived from electromagnetism. And what's that you ask. ELECTROMAGNETISM is a force that affects all positively and negatively charged particles articles those with opposite charges attract while ones carrying like charges. Repel each other. Not only does this principle. Keep magnets on your fridge. But it's also the reason why solid solid objects are able to retain their shapes compared with electromagnetism. Gravity is rather weak surprisingly enough. It's actually the weakest of the four fundamentals including including the so-called weak force. We'll get to that one in a bit. A gravity is the attraction of any two objects in the universe to another moons. Dust motes coyotes. Whatever ever everything exerts gravity on every other thing but at least one of the things in question has to be pretty massive in order for it to make much of a difference? That's why we you don't have dust mites orbiting our heads like asteroids and why we don't fall into orbit of coyotes when we encounter them but let's turn to the appropriately named strong force course. This is what hold Tomic nucleus together. Even in spite of their charged protons which are constantly trying to escape and last but not least. There's the Weak Force Aka. The weak interaction. This one is the hardest to explain and honestly I'm not an expert here but it's the force by which which subatomic particles can transform by decaying into different particles by losing boasts on which disintegrates into positron and or neutrinos this week force force fuel certain kinds of radioactive decay which means it's responsible for everything from medical imaging to the radiometric dating that researchers use to determine the ages of fossils thousand artifacts to the nuclear fission that occurs in the sun. So kind of a big deal. Scientists have a theory that nicely describes three of those forces known these standard model of physics. It's made up of various measurements and mathematical formulas. It also breaks down. Elementary particles into categories is an subcategories. We spoke by email with mit physicist. Richard Milner he explained. The Standard Model of physics is the present framework for describing describing the subatomic world at all energies. It was developed post World War to end. I count at Least Eighteen Nobel prizes in physics since nineteen fifty that have been awarded for contributions tribulations to its development alike all good theories. The Standard Model has accurately predicted numerous scientific breakthroughs including the discovery of the elusive higgs. Boson particle back in two thousand twelve yet. It doesn't answer every question. The Standard Model offers no explanation for gravity and it hasn't brought scientists any closer to understanding dark matter a mysterious ingredient that makes up about twenty seven percent of our universe. Here's where crossing a Hawkeye and company. Come in during a twenty fifteen experiment at the Hungarian Academy of Sciences Institute for Nuclear Research They watched excited brilliant eight atoms decay inside a particle Michael Accelerator normally this process releases light which is later converted into electrons and positron are a type of Subatomic particle with a positive charge. And sure enough. That's what happened but then things got interesting. Normally brilliant eight decays predictable fashion yet. A weirdly Lee high number of these electrons and positron repelled each other at a one hundred and forty degree angle to explain the surplus crasner. Hawkeye's team argued that a never before seen particle had been formed as the atoms decayed by their calculations this theoretical subatomic body would have a massive around seventeen million electron-volts on volts. They went ahead and named the x seventeen particle and now ex seventeen is again making the news. Recently the same Hungarian Carrion scientists detected an anomaly indicates samples of helium four according to their archive paper. An unforeseen surplus of positron and electrons were released. Possibly because another seventeen particle was created. If this mystery particle exists. It might be something very special. Maybe just maybe it's a newfound carrier boasts on both sides are spinning particles that probably lack internal structure their known to carry forces making them an integral part of the standard model under the standard model. Milner Explains Forces take place by exchange of the carrier Bussan's between other subatomic particles articles. It's said each of the four fundamental forces has its own corresponding boasts on the one that transports gravity hasn't been found yet but the carrier bones associated it was strong force. Weak force electromagnetism are well documented. Presumably at seventeen would be the Kargbo sound for a fifth fundamental force that we never knew existed listed and perhaps said force is somehow related to dark matter but or getting ahead of ourselves. There's no hard proof that x seventeen exists. It's in the first place. The European Organization for Nuclear Research better known as sern has yet to find any trace of the particle and the new archive paper is still awaiting peer review and replication from other scientists milner and his colleagues have devised a proposal to try to generate seventeen particles in a scattering experiment at the Thomas. Thomas Jefferson National Accelerator Facility in Newport News Virginia at present the standard model does account for any new fundamental forces. So if the x seventeen and the fifth force that allegedly carries a real we'll have to modify the good old standard model at any rate. It's clear the Potomac world is still rife with

Richard Milner Hawkeye Physicist Hungarian Academy Of Sciences Thomas Jefferson National Acce European Organization For Nucl MIT Tomic Newport News Virginia Sern Thomas
Could There Be a Fifth Fundamental Force?

BrainStuff

06:38 min | 3 years ago

Could There Be a Fifth Fundamental Force?

"The four fundamental forces are the most important quartet in science so far is anyone's been able to prove the universe is governed by these forces forces gravity electromagnetism the strong force and the weak force. But maybe this foursome isn't alone in two thousand fifteen. A Hungarian and team led by physicist Attila. Credit Hawkeye reportedly discovered new evidence for a fifth fundamental force. Something previously unknown to science. The the group uploaded another paper about the subject to archive a research database in October of two thousand nineteen while many scientists are skeptical about these findings. The research search does give us an occasion to talk about the major forces that we all take for granted the Fab four fundamental forces are irreducible meaning. They can't be broken down into other more basic forces. These are the core phenomena behind every other known type of physical interaction. For example friction tension and elasticity busy are all derived from electromagnetism. And what's that you ask. ELECTROMAGNETISM is a force that affects all positively and negatively charged particles articles those with opposite charges attract while ones carrying like charges. Repel each other. Not only does this principle. Keep magnets on your fridge. But it's also the reason why solid solid objects are able to retain their shapes compared with electromagnetism. Gravity is rather weak surprisingly enough. It's actually the weakest of the four fundamentals including including the so-called weak force. We'll get to that one in a bit. A gravity is the attraction of any two objects in the universe to another moons. Dust motes coyotes. Whatever ever everything exerts gravity on every other thing but at least one of the things in question has to be pretty massive in order for it to make much of a difference? That's why we you don't have dust mites orbiting our heads like asteroids and why we don't fall into orbit of coyotes when we encounter them but let's turn to the appropriately named strong force course. This is what hold Tomic nucleus together. Even in spite of their charged protons which are constantly trying to escape and last but not least. There's the Weak Force Aka. The weak interaction. This one is the hardest to explain and honestly I'm not an expert here but it's the force by which which subatomic particles can transform by decaying into different particles by losing boasts on which disintegrates into positron and or neutrinos this week force force fuel certain kinds of radioactive decay which means it's responsible for everything from medical imaging to the radiometric dating that researchers use to determine the ages of fossils thousand artifacts to the nuclear fission that occurs in the sun. So kind of a big deal. Scientists have a theory that nicely describes three of those forces known these standard model of physics. It's made up of various measurements and mathematical formulas. It also breaks down. Elementary particles into categories is an subcategories. We spoke by email with mit physicist. Richard Milner he explained. The Standard Model of physics is the present framework for describing describing the subatomic world at all energies. It was developed post World War to end. I count at Least Eighteen Nobel prizes in physics since nineteen fifty that have been awarded for contributions tribulations to its development alike all good theories. The Standard Model has accurately predicted numerous scientific breakthroughs including the discovery of the elusive higgs. Boson particle back in two thousand twelve yet. It doesn't answer every question. The Standard Model offers no explanation for gravity and it hasn't brought scientists any closer to understanding dark matter a mysterious ingredient that makes up about twenty seven percent of our universe. Here's where crossing a Hawkeye and company. Come in during a twenty fifteen experiment at the Hungarian Academy of Sciences Institute for Nuclear Research They watched excited brilliant eight atoms decay inside a particle Michael Accelerator normally this process releases light which is later converted into electrons and positron are a type of Subatomic particle with a positive charge. And sure enough. That's what happened but then things got interesting. Normally brilliant eight decays predictable fashion yet. A weirdly Lee high number of these electrons and positron repelled each other at a one hundred and forty degree angle to explain the surplus crasner. Hawkeye's team argued that a never before seen particle had been formed as the atoms decayed by their calculations this theoretical subatomic body would have a massive around seventeen million electron-volts on volts. They went ahead and named the x seventeen particle and now ex seventeen is again making the news. Recently the same Hungarian Carrion scientists detected an anomaly indicates samples of helium four according to their archive paper. An unforeseen surplus of positron and electrons were released. Possibly because another seventeen particle was created. If this mystery particle exists. It might be something very special. Maybe just maybe it's a newfound carrier boasts on both sides are spinning particles that probably lack internal structure their known to carry forces making them an integral part of the standard model under the standard model. Milner Explains Forces take place by exchange of the carrier Bussan's between other subatomic particles articles. It's said each of the four fundamental forces has its own corresponding boasts on the one that transports gravity hasn't been found yet but the carrier bones associated it was strong force. Weak force electromagnetism are well documented. Presumably at seventeen would be the Kargbo sound for a fifth fundamental force that we never knew existed listed and perhaps said force is somehow related to dark matter but or getting ahead of ourselves. There's no hard proof that x seventeen exists. It's in the first place. The European Organization for Nuclear Research better known as sern has yet to find any trace of the particle and the new archive paper is still awaiting peer review and replication from other scientists milner and his colleagues have devised a proposal to try to generate seventeen particles in a scattering experiment at the Thomas. Thomas Jefferson National Accelerator Facility in Newport News Virginia at present the standard model does account for any new fundamental forces. So if the x seventeen and the fifth force that allegedly carries a real we'll have to modify the good old standard model at any rate. It's clear the Potomac world is still rife with

Are we talking about GE or GM?

MarketFoolery

13:48 min | 4 years ago

Are we talking about GE or GM?

"That Tuesday, April nights. Welcome to Mark Tillery. I'm Chris joining me in studio today from fam- fund, a proud graduate of the university of Virginia law school Bill Barker. Congratulations to your Cavaliers. Thank you. Thank you very much. It was good run heck of a run and we've got condolences to our colleague, Mike Robinson whose Texas Tech grad who's at the basketball game last night. But congrats to. Metropolitan our colleague, and the many UVA graduates who worked here at headquarters. Lot of lot of orange and blue around the office today a lot of people fly in the colors. Why not they should? Yeah. Yeah. I mean, we're is a Virginia company. That's true. That's true. People don't know that. And let's face it. When it comes to major college sports, you're probably going to have a better shot at winning national title with your law school than your undergraduate alma mater, time will tell I guess, I guess we'll say we're going to dip into the full mailbag. We've got news from the healthcare industry the packaged foods industry. Let's start with this get the popcorn ready because on Wednesday. The CEO of the biggest banks in America are heading to Capitol Hill to testify before the House Financial Services committee. The rundown is Jamie diamond from J P Morgan Michael bat from city, David Solomon from Goldman Sachs, Jim Gorman from Morgan Stanley, Brian moynahan from Bank of America will get to Wells Fargo in a second coincidentally or maybe not coincidentally Bank of America announcing today that the company is raising the minimum wage at its company to twenty dollars an hour. And if nothing else the timing of that announcement makes Wednesday probably a little less painful for Brian moynahan hand testifying on Capitol Hill. Yeah, I think so I don't think there's much coincidence about it. I think it's. We'll see it seems like a smart political play at the moment getting the headlines that that they want and positioning, and they'll know expound on that a bit in front of the cameras. So I think that it takes some of the wind out of the sales of of those that are going to attack at least Bank of American. I, you know, I think every everybody is going to be under pressure to to respond. So in terms of Wells Fargo. At the moment. If someone from Wells Fargo is on the list to testify I haven't seen it yet. Doesn't mean. It's not going to happen. We've still got time before the hearing. But I'm reminded of a conversation. I had couple years back with Paul liner. Who's covered the automotive industry for thirty plus years, and we have him on motley. Fool money pretty much every year around the North American International auto show in January and talking to Paul about how. About the ripple effect of. Automaker X having some sort of large failure. And failure to disclose. The failure of whatever the technology is whether you know, it's Volkswagen in the emission standard and just sort of the ripple effect. Like, if you're if you're any of the other automakers you like 'cause they they all pay for it in some small way. And by the same token Wells Fargo just continuing to screw up in terms of their own culture the fake account scandal. Tim Sloan who was there when the scandal? Happing happened not being the right person to try and clean up the mess. And then you know, he is shown the door. If you're any of these other CEO's, I have to believe in the back of their mind at some point tomorrow. They want to say, hey, at least, we're not Wells Fargo. I mean, it just it. It's one of those things where yes, it's a Wells Fargo problem. But it really does spread to the other. Banks. Yeah. I I think that they'll probably to the extent they can sort of redirect the questioning toward. Oh, well, Wells Fargo. You probably would've enjoyed having them here to kick around. And I was I was looking up some of the data on what's been paid. So far post. Oh, eight oh nine and there have been about a about a quarter of a trillion dollars in fines against the banks and not all that cash. Some of that is as been settled in by loan forgiveness, and and some other credits, but it's a, you know, in terms of there was a bail out of the banks true enough, and they paid back the money that they were in some cases forced to borrow from from the federal government. But but that was paid back and they have paid fines. And I don't know that that it is a strong thing to say, hey, look, we've already paid a quarter of a trillion, you know, combined in fine. So don't act like we. Haven't you know, already been punished? That's that's not going to get them anywhere. But you know, they can talk bleakly I guess about having made amends at times, well and one difference between now and five years ago eight years ago that sort of thing is you can make a pretty strong case that big banks are no longer number one on capitol Hill's enemy list in terms of the business world. I think the big tech has probably supplanted them. So for any CEO who wants to try out there? Well, hey, at least we're not Wells Fargo. They could just as easily and by the way, we're also not Facebook. Yeah. Well, and I don't know if that's going to go anywhere either. As I so they've got to create the accentuate the positive part of the story in this twenty dollar minimum pay which Monahan is said, look anybody who works here is going to be making at least forty one thousand dollars. A year. That sounds pretty good as if you're thinking in terms of a minimum wage job of which there are essentially none INA back, right? You've got Bank tellers to the degree that that's a major part of the employment. Banks. I don't know how much that's the case. But you don't have a lot of employees who are probably, you know, competing with at any of these banks who are thinking, what are the other minimum wage jobs that I would be comparing this against, but I think it is a positive, and they're pointing to it in part as something that they are doing their they're connecting the dots between the tax cut and making this sort of passing on some of the profits that they have they're sitting on from from the massive tax cut. So you know, that will get them some of the way with maybe about. You know, one half of the aisle one side of the aisle will will allow them to talk about that and the other half, probably less. So. Like, I said get the popcorn ready. Let's move onto Cerna Corp, which is healthcare. Technology firm, sir has reached an agreement with starboard value. Well, known activist investors to add four members to the board of directors Cerna is also buying back. One point two billion dollars worth of stock. Which of these two things is pushing shares of sir up ten percent today. Because my assumption is just based on the fact that shares of Sern are have sort of treaded water over the last five years or so I'm assuming it's the board seats, I think, yes. Wing along in the the line that starboard is is recommending it's remarkable starved really doesn't have that much of Cerna. I think a red by one percent of Cerna stock, but there's whole laundry list of changes that are going to be made including the strategic business unit being eliminated. I think that. Dividend was just recently, the started by sir. And it looks like they are going to be forced to change some of their capital allocation, including at least authorization to buy back up to one point two billion whether that gets follow through or not we'll see. But I think the board search is, you know, that's that's all part of the equation. I don't know how you can separate a twelve percent move when it opened now it's maybe eight or nine percent. And you know, what part of that is scribe to what part of this whole package. I'm not looking knock starboard value. But I am curious about something that you just said, which is that start value only has a one percent of Cerna Stott. How are they getting four seats on the board? If they only have one percent of the stock. The seems like something you get when you have at least five percent of the stock and really closer. To ten percent of the stock. I agree. I was surprised when when I read that. And so I want to admit that I need to make sure that that's the case before going too far. But if it is the case, you can you can guess that they have some other shares that they are in communication with that are on their side because. Yeah, one percent is one percent. If that's all that. It means is hey, sell your one percent if you know that unhappy. I mean, we we don't you don't have as much power as you think. But if they have plenty of people on their Rolodex, and you know, nowhere to push the buttons and organize the the votes that proxy time than that. That's a different story. Yeah. I was gonna say if in fact, it's only one percent then that opens up a whole world of opportunity for activist investors, potentially. Our Email address is market fully at full dot com. Questioned from dang who's writing from China, dang rights. I've been listening to market fuller since I started investing in stocks and twenty fourteen lately, I've been looking at some large cap stocks, which may not grow that fast and cites as examples Kroger General Motors and some airlines docks. Goes on to I'm considering their p values which are below ten making them cheaper than the market average. Are they bargain or are they potential traps? The age old question dang value play or value trap. Because that is always the thing that sucks in. I was gonna say value investors. But really a lot of investors just, you know, their growth investors who just see a stock. Get knocked down twenty percent in one day and immediately start thinking. Well, look, it's it's on sale twenty percent. So you know, maybe I should be jumping in here. How do you help people think about solving this question because we're talking about more than one stock here, and we're not gonna go through like Kroger. General, you know, we're not gonna go through all of them. But what do you sort of look for once once you've made that initial calculation of? Okay. Here's a large cap, it's not going away. And sometimes we're looking at large companies that are paying dividend. So there's some reason to buy them, maybe the businesses and setting the world on fire, but you've done the math. And you say we'll look from peace stamp this significantly cheaper than the overall market. Why should I buy a few shares? Yeah. Is a good question. And to take the p so it's I'm looking at data that right now in comparison to its forward earnings GE for instances at five point eight times forward earnings. And boy that sounds street at is cheap over the last five years. The average is six point two. So usually for the market for the last five years for GE over g so g is not it's maybe, you know, five percent cheaper than its five-year average in comparison to the forward earnings expectations. And why is it so cheap one the Ford earnings tend to be overly optimistic not only for GE, but for everybody at this time of the year, you're still going out one quarter ninth and yet reported, and so there is the typical enthusiasm about the year ahead, and as the year goes down and companies report, and they say, you know, we're gonna we're not gonna Aaron quite as much as we may be thought we did. Or as you thought we did. Additionally, just it's a highly cyclical industry autos and auto sales of begun to level in decline, and

Wells Fargo Bank CEO Virginia UVA Cavaliers Mike Robinson Brian Moynahan Basketball Bank Of America Mark Tillery Bill Barker Paul Liner GE Chris Volkswagen
Marking 30 years of the web, creator Tim Berners-Lee looks back

Latest In Tech News

00:58 sec | 4 years ago

Marking 30 years of the web, creator Tim Berners-Lee looks back

"On this date in nineteen eighty nine. Tim burners Lee submits a proposal. Sern for developing a new way of linking and sharing information over the internet. It was the first time he proposed such a system that would ultimately become the worldwide web. However, this proposal was a relatively vague request to research details and feasability of such a system. He would later submit. A proposal November twelfth nineteen ninety that would much more directly detail to actual implementation of the worldwide web today. So while some people consider today the birthday of the worldwide web, I put forth November twelve nineteen ninety as a more accurate date. But be that as it may still had the idea granted, he probably had to do a little bit more thinking about it. But interestingly enough, Tim burners Lee, I believe he was just interviewed on some news outlet talking about the future of the internet thirty years later in his visions than ideas and well happy thirtieth. To the World Wide

Tim Burners Lee Thirty Years
Protesters march through Paris amid fears of new violence

BBC World Service

00:44 sec | 4 years ago

Protesters march through Paris amid fears of new violence

"That caused people to panic inside. Try and flee trampling over each other. According to officials and that caused a number to be crushed. We're hearing around one hundred have been injured about ten of them seriously. Now, they've been taken we understand to two nearby hospitals where the being treated. According to the United States is too far ripe protester guilty of murdering of women when he drove his car into a crowd of counter demonstrators to white supremacists. Rally in Charlottesville Virginia last year. A jury took less than a d- to convict James fields and all ten charges. He faced. You're listening to the world news from the BBC. The Japanese parliament is given its final approval to a controversial new law. Allowing hundreds of thousands of foreigners into the country to ease chronic labour shortages from April next year, they'll be allowed to take up jobs in various sectors, including construction a nursing Japan has traditionally been wary of immigration, but the government argues that bringing in more foreigners unavoidable because of the country's aging population opposition parties, see the new law has been. He's totally drafted. The Brazilian president Michel Temer says he is asked the governor of the state of rhymer to handover administrative power until the end of the year with the details. Here's candy. Mr Thomas said the federal intervention was needed to regain control after a series of protests and strikes by prison guards and police over pay ROY Raymond has seen violent prison riots this year, and the government is worried he could destabilize the state that borders Venezuela, but there's another problem to last month, the central government had to partially intervene in ROY Rama to deal with tens of thousands of Venezuelan migrants. The state authorities said they didn't have the resources to deal with them alone. The Jamaican reggae star. Buju Banton has returned to the island after being released from prison in the United States. He served seven years in jail in Georgia after being convicted of intent to supply kookiness, dozens of fans gathered at the airport in Kingston to welcome home. Would you Benton was Jamaica's biggest reggae star since elite Bob Marley? Australian schoolchildren have led protests by thousands of people against the plant coal mine in the state of Queensland the children invited adults to rallies in major cities demanding that the Indian company Adani abandoned, the project sponsor, Danny vowed to press ahead with the mine little be considerably smaller than original BBC news. Hello again. You're listening to weekend with me Pasqua Harsha and coming up in this hour. We'll be discussing a new trend co-parenting that's springing up a child by parents who are not and never have been romantically involved. His father will Kamei putting to bed. Read them and not nighttime story anything a normal. Father would you and it really works and YouTube called split up because you've never been together. Yeah. Exactly. And we are they are sleep best friends. Find out what our panel. Thank of that veracity Pillay in Johannesburg and Jonathan Steele here in London studio with me, but before we get into that Jonathan you've come to us fresh from a conference on Syria in London this week. This is a very interesting conference at the London School of economics, mainly with Syrians taking part. Basically the exiles. So they're not program in any way. But they were quite depressed about what was happening because who knows wars winding down, and that means that there's less killing going on the government is determined to sort of beaver said one of the academic said to be fortification mode. They want to make sure that this new resurgence of violence and song. And it even goes the question, whether the government wants refugees to come back because as one of them, again, another one put it the government doesn't have the resources not only not to feed people coming back to police them because the sources fear that there could be a new uprising us there wasn't twenty eleven and even talking about people coming back does that mean that there is a sense that the conflict is winding down. I think there's a definite sense. I think everybody agrees including opposition people. Hold up mainly in. Live in northwest, Syria. The rest of the country's back onto government control, the whole of Damascus big cities, Hampson Hammond. And. Leper so fighting house really calm down and the government claims they control what they call can the terrible phrase useful, Syria. The area. They consider doesn't matter in the northwest doesn't matter, but the big cities in the spine of the country, which runs no south from leopard entre Moscos's back from and government is very very interesting to hear the you say there's consensus that the conflict is winding down and get one of our contributors recently was talking about standing on the balcony of her home in Damascus and seeing the bombs falling on another part of the city will I think that's a little bit out of date. Now that used to be the case when I lost about a year ago. You could hear the poems and see the plain song. After the fall of Houston Huta in the spring of this year, pretty much, Damascus suburbs and back government control back under military control. But as hinting from this conference is the whole question of political Israel and government is not going to make any concessions, those can be no compromise or to alter the in fact, the Geneva talks dead dead sing because the government is determined to consolidate its victory, forty five country grounded Sern regime and not make any concessions tool, and as our other guest on the line from Johannesburg knows very well one thing is is the struggle. And another thing is the peace afterwards and Borussia Pillay on the line from Johannesburg. You've been looking into something else. We talk about South Africa we used to as the rainbow nation, but you have been looking at an undecided of racism within. Would you say? Within the black community. Absolutely. The skull within the black community and within the Asian community. And in fact, many communities I myself am of south Indian descent, so I really had from both sides being sort of sixth seventh generation growing considering by South African as well as of Indian descent and seeing just how these tropes play out. And because it's so much of a black lives have been discussed in relation to to whiteness and colonialism. It's only now that we started to have this conversations within black communities, which I think is really important that we start talking about how have we internalized notions of self hatred, and so on and a one of the one of the obvious things is the skin lightening creams, which understand you're searching. Yes, I'm actually writing a book on the topic of color rhythm and cutter ISM. You know? It's it's got so many. Sort of impacts in our society. One of them is of course, you know, the most obvious one is the very damaging nature of skin lightening creams in South Africa. We were fortunate enough to had those band very early on in in in our in, you know, in the sixteenth s the damage became apparent and people still use them they're widely available in black markets. And and you know, it's not just about the health risk. There's so many studies that show that lighter skinned people are lacking black people get much more in all kinds of opportunities job opportunities. You only have to look at Hollywood to see this. The light skinned the lighter skinned black woman is is usually cost darling. And the darker skinned black woman is cast as the villain and just how it is becoming in growing and growing conversation with these kind of things are being unpacked, and it really reaches across the world. And when I visited India for the first time, I was considered extremely dark, and and it's very interesting to me because I grew up under. The influence of black consciousness of Steve Biko where you taught to love yourself, and that influenced my understanding of my own skin color, and in India, it really was seen as a huge, Mark. I could not find makeup in my skin color. And I'm I could not find any creams that did not have skin lightening in them. And as you say this is prevalent across the rest of Africa, the Congo, Nigeria and so on. Coming. You mentioned black consciousness. I was just wondering right now, the ANC is. Emphasizing blackness much more. In fact, I think Tabor Mbeki recently said the ANC is becoming a black party. He was saying that was a criticism and you've got the economic freedom fighters. Rules, pushing sort of black power entering into this debate on on this sort of saying to toback people you shouldn't fool for this nonsense about calories and trying to look whiter than white. So absolutely. This is a very much a debate that I think is raging amongst the diaspora and blackmail across the world, whereas in South Africa because of the fierce black pride and a big movements towards owning your blackness. It would be considered very unfashionable to to avert. We say these things so it's really subtle. It's really a subtle thing. You know, they'll be adobe slang terms. Coined Appalachia skinned woman, yellow bone, and there'll be a preference towards them in music videos, and in also liberty culture. They'll be gradual lightning of our liberties getting lighter and lighter because they're using something called glutathione. Injections, which is not tested at all in terms of health implications, and literally lightens your skin. So there is this professing publicly of being proudly black while I'm working really hard to conform to a standard of beauty in terms of intensive one skin color and other aspects of how presents themselves. Hey up of fat. So while the ANC are very pro black. You know, there's so many issues for them to tackle. They haven't quite got onto this one yet. Well, let's hear more about that issue later in the program rationally Pillay on the line from Johannesburg and Jonathan steel here in London. But right now, let's go to France where the capital is waking up amid fears of another weekend of violence and new nationwide protest of the zone. All the yellow vests is due to take place in the coming hours, the government as well as major unions have called for calm asking protesters to stay away from places where many of last week's more violent incidents took place in the capital, but also in the rest of the country to in Paris, major attractions such as the Eiffel tower will remain closed today. But all of this is despite concessions from president Emmanuel Macron earlier this week, including abandoning a planned increase on fuel tax. And yet that hasn't appeased everyone tensions remain, very high as Hugh Scofield reports from Paris. It's

Government Johannesburg Borussia Pillay Damascus ANC United States BBC London South Africa Syria President Trump Virginia Buju Banton James Fields London School Of Economics Charlottesville Youtube Michel Temer Pasqua Harsha Paris
A Beginners Guide To CERN

A Moment of Science

02:00 min | 4 years ago

A Beginners Guide To CERN

"You might have heard of Sern also known as the European organization for nuclear research, located just outside of Geneva, Switzerland, they're interested in what matters made of and how it all works together to put it another way these physicists research particles such as electrons, quirks, glue, on's and more and the forces that act upon them to do this Sern uses particle accelerators, which exceleron particles in beams and then collide those beams with each other or certain targets. These beams are exceleron by electric fields and steered by magnetic fields. The accelerators are either circular where the beans race round and round or straight where they shoot one into another the resulting collisions caused new particles to form and specialized detectors track their speed, energy and charge. The biggest exceleron and the biggest machine. Gene. In the world is the famous large Hadron collider or l h c at seventeen miles in circumference this accelerator forces to beams to travel at near the speed of light before smashing them together. The l h c is used for some of surnames most important experiments such as its exploration of the Higgs bows on a particle. That would explain why mass exists at all. What else does Sern do it researches basic aspects of the universe such as light the big bang, antimatter black holes, gravity and much more? And it created the worldwide web in one thousand nine hundred nine scientists at universities around the world, including Indiana, Purdue and Notre Dame are active participants in Sern research unlocking the secrets of matter. It seems that some big ideas can come from tiny particles. This moment of science comes from Indiana University. I'm Yahoo Cassandra.

Sern Indiana University Switzerland Geneva Indiana Higgs Yahoo Purdue
'Jersey Shore' star Mike 'the Situation' Sorrentino vows to 'come back stronger' after being sentenced to 8 months in prison

WBZ Morning News

00:29 sec | 5 years ago

'Jersey Shore' star Mike 'the Situation' Sorrentino vows to 'come back stronger' after being sentenced to 8 months in prison

"Five twenty one reality TV star, Michael the situation, Sern, Tino and his brother. Mark are sentenced to federal prison on tax evasion charges. The thirty seven year old are Tino is sentenced to eight months in prison Friday in Newark, New Jersey court his brother was sentenced to twenty four months in prison. They allegedly concealed their cash income. Michael gained fame on the show. The jersey shore he and his brother created businesses such as NPS entertainment

Tino Michael New Jersey NPS Newark Mark Sern Twenty Four Months Thirty Seven Year Eight Months
John McCain, Dr. Henry Kissinger and America discussed on The Daily Article

The Daily Article

00:39 sec | 5 years ago

John McCain, Dr. Henry Kissinger and America discussed on The Daily Article

"Filled with paradoxes. Begin with a name. We honor America's one hundred sixty million laborers by giving them a day free from labor. Then we call their holiday Labor Day. However, the name is unfortunately appropriate for our largest labor group retail employee's. They'll have one of their longest workdays today as Americans flood into stores for Labor Day sales Labor Day could have led to a four day weekend, but congress intervened the first labour day was on a Tuesday in eighteen eighty two. In eighteen ninety four. Congress moved the holiday to the first Monday in September. So when you go back to work tomorrow, blame them, the good news is that the

John Mccain Dr. Henry Kissinger America Jim Denison Congress Washington National Cathedral Charles Spurgeon Sern Writer KAT Ohio Nishit Lord Ninety Four Year Four Day
Researchers interpret new experimental data aimed at showing dark matter interacts with ordinary matter

This Is Only A Test

01:22 min | 5 years ago

Researchers interpret new experimental data aimed at showing dark matter interacts with ordinary matter

"You remember going to Sern couple years ago now and when they were talking about the the discovery of the Higgs bows on the confirmation when the key elements in that discussion wasn't that they, they didn't observe the Higgs bows on directly. They saw the decay products inference. Yeah, and so they are used MU on decay to sort of track back that the Higgs boson occurred. And this week Sern announced that they doubly confirmed in a different decay pattern because Higgs bows on supposedly has more than one decay pattern that what we saw. So what they tracked was actually a bottom antibody court. Decay pattern. Yeah, but naming pattern in in court. Pretty great. We haven't talked about charm corks very much here on on the podcast, but. The standard model predicts something like fifty to sixty percent of Higgs boson decays I think it's fifty. Seven percent would decay in this bottom antibody quirk. Pattern and they finally saw it. So this does just confirm more aspects of the standard model. And if you remember most of that trip, they were like looking for ways to break the standard model of physics. This adds the confirmation, but they're hoping that it's just another point along the way to breaking it.

Higgs Jeremy Sern Wasser Wass San Francisco Hugh Paris LA ZIA RAY Forty Million Years Seven Percent Sixty Percent