15 Burst results for "Robert Cedar"

"robert cedar" Discussed on The Naked Scientists

The Naked Scientists

06:29 min | 5 months ago

"robert cedar" Discussed on The Naked Scientists

"And immunisation outlined plans for an autumn booster program to top up the immunity of everyone over fifty against covert nineteen. But one thing that hasn't been clear so far is how much do we need in order to be protected where some people despite vaccination still able to catch corona virus infection but not become on. Well now we have a bit more clarity. Because as robert cedar explained to chris smith. He's done some catholic experiments on monkeys which developed covert nineteen infections in a similar way to humans. This has revealed the level of antibody. That's needed to protect both against severe lung disease and also against just catching and say potentially passing on the infection. The to turn out to be different and this means we now have a benchmark to aim for when or indeed if we embark on a programme of booster doses this autumn when you give the vaccine trying to measure the type of immune response in the blood that would tell you that you would be protected in the lungs or in the nose. You wanna protect people. I in the long so they don't get severe disease and you liked to protect people in the upper airway so it might prevent them from getting symptoms of a cold and then you would not be able to give it to somebody else. Was this not known already given that we have put billions of doses of vaccines into the world's population. So far there had been a couple of studies that showed that the higher levels of antibodies. You had in the blood measure of the immune. Response the better off. You were for protection. So our study in animals provided greater specificity to really define kind of exactly what the level of antibody response in the blood was to mediate protection in either the long or the nose. So this is sort of a way of standardizing when we give someone i vaccine of some type in particular. What's the threshold level of antibody. We probably need in the blood either to protect their lungs or to protect the upper airways and therefore protect them. Either from just getting ovid or from transmitting the infection. That's exactly right in the reason. Why if you have a precise measurement is it would allow you if people had their blood measured and you immuno-compromised or you were older or had a pre-existing illness if your antibodies were below that level it might indicate that you're at greater risk and it might indicate that you would need another shot of the vaccine to put you above that threshold so it can be very helpful. In guiding perhaps people at greater risk for over a long period of time whether immune response is waning and you need a boost. I'm it also helps you with Other vaccine approaches. Where if they haven't gone through the full process of a large Phase three study. But they're they're vaccine shows very high levels of those immune responses you might be able to use the metric data to suggest that that vaccine is very likely to work and possibly being able to facilitate approval of another type of vaccine based on achieving that certain metric. Does it shed any light on something. We're increasingly seeing. Perhaps in the light of having a very high fraction of the uk population now vaccinated is that we seem to be seeing lots more asymmetric infections and people are a bit surprised. Because i think we'll have been vaccinated. How catching this thing at all. Do your results give us some insights into how that's happening. Yes the key. I think one of the key findings of the study was that we showed that less. Antibodies or less immune response is required to protect you from severe disease in the lower airway. Then what is required in the upper airway. And i think that explains why all the vaccines are very good. It preventing severe disease and but the year now starting to see a differentiation of vaccines for protection against mild infection or eysenck dramatic infection in the upper airway in. I think it would just make sense that you just need more of an immune response in the upper airway to limit infections especially with something like the delta variant where there's a lot lot more virus in the nose and so the better vaccines that induce higher immune responses that translates into having higher responses in the upper airway. And so. that's why of axion could protect you from going to the hospital but might not protect you. From ou- infection or transmitting. It is wanting to predation of your findings then that actually if we drove everyone's immune response as hard as possible. We could get everyone to point where that have enough antibody where they just couldn't be infected and the moment just not doing that enough. That's a very good point and that is potentially rationale for giving people another vaccination are a boost is if you could boost antibodies higher it might sustain your continued very high level protection against severe disease member. All vaccines are basically ninety to one hundred percent protective and so if you boost you sustain that but if you had more antibodies perhaps in your upper airway might that serve to limit transmission and when you look at the delta variant which is existing it probably a hundred thousand fold more virus in the nose. Might that be the only way that you can accomplish. That is with another boost to get higher levels of antibodies. The alternative in the future might be for things like colbert and upper respiratory infections to have vaccines that might be given to induce immune responses directly in your upper airways. And might that be better. And i think that that will be an interesting area of research. Going forward robert c. To that he's based at the nih. Vaccine research center in washington dc and that study is just come out in science advances..

robert cedar chris smith lung disease mild infection eysenck dramatic infection cold severe disease uk colbert robert c Vaccine research center nih washington dc
"robert cedar" Discussed on The Naked Scientists

The Naked Scientists

01:59 min | 5 months ago

"robert cedar" Discussed on The Naked Scientists

"Takover i on recently the joint committee on vaccination and immunisation outlined plans for an autumn booster program to top up the immunity of everyone over fifty against covert nineteen. But one thing that hasn't been clear so far is how much do we need in order to be protected where some people despite vaccination still able to catch corona virus infection but not become on. Well now we have a bit more clarity. Because as robert cedar explained to chris smith. He's done some catholic experiments on monkeys which developed covert nineteen infections in a similar way to humans. This has revealed the level of antibody. That's needed to protect both against severe lung disease and also against just catching and say potentially passing on the infection. The to turn out to be different and this means we now have a benchmark to aim for when or indeed if we embark on a programme of booster doses this autumn when you give the vaccine trying to measure the type of immune response in the blood that would tell you that you would be protected in the lungs or in the nose. You wanna protect people. I in the long so they don't get severe disease and you liked to protect people in the upper airway so it might prevent them from getting symptoms of a cold and then you would not be able to give it to somebody else. Was this not known already given that we have put billions of doses of vaccines into the world's population. So far there had been a couple of studies that showed that the higher levels of antibodies. You had in the blood measure of the immune. Response the better off. You were for protection. So our study in animals provided greater specificity to really define kind of exactly what the level of antibody response in the blood was to mediate protection in either the long or the

robert cedar chris smith lung disease mild infection eysenck dramatic infection cold severe disease uk colbert robert c Vaccine research center nih washington dc
What Level of Antibody Is Needed for Protection Against COVID-19?

The Naked Scientists

01:59 min | 5 months ago

What Level of Antibody Is Needed for Protection Against COVID-19?

"Takover i on recently the joint committee on vaccination and immunisation outlined plans for an autumn booster program to top up the immunity of everyone over fifty against covert nineteen. But one thing that hasn't been clear so far is how much do we need in order to be protected where some people despite vaccination still able to catch corona virus infection but not become on. Well now we have a bit more clarity. Because as robert cedar explained to chris smith. He's done some catholic experiments on monkeys which developed covert nineteen infections in a similar way to humans. This has revealed the level of antibody. That's needed to protect both against severe lung disease and also against just catching and say potentially passing on the infection. The to turn out to be different and this means we now have a benchmark to aim for when or indeed if we embark on a programme of booster doses this autumn when you give the vaccine trying to measure the type of immune response in the blood that would tell you that you would be protected in the lungs or in the nose. You wanna protect people. I in the long so they don't get severe disease and you liked to protect people in the upper airway so it might prevent them from getting symptoms of a cold and then you would not be able to give it to somebody else. Was this not known already given that we have put billions of doses of vaccines into the world's population. So far there had been a couple of studies that showed that the higher levels of antibodies. You had in the blood measure of the immune. Response the better off. You were for protection. So our study in animals provided greater specificity to really define kind of exactly what the level of antibody response in the blood was to mediate protection in either the long or the

Joint Committee On Vaccination Robert Cedar Chris Smith Lung Disease Cold
"robert cedar" Discussed on KCRW

KCRW

06:28 min | 2 years ago

"robert cedar" Discussed on KCRW

"It's morning edition from NPR news I'm Steve Inskeep and I'm a well can good morning the U. N.'s world food program says eight million people in Zimbabwe don't have enough food to meet their basic daily needs that is half the country's population and the W. F. P. says it's a profound crisis Jerry Burke is a spokesman for the world food program he was in Zimbabwe last week and he told me what he saw there well it's a very very grim situation infected it's a national catastrophe nothing short of that eight million people half the population on the brink of starvation literally not knowing where the next meal is coming from so many families desperate hurting struggling they're skipping meals they're taking their kids out of school they're selling off what little they have by way of precious belongings family assets malnutrition rates are rising so it's an absolute disaster what what is behind this disaster well there are two principal contributing factors one is climate change Zimbabwe like much of the rest of southern Africa has had one normal rainy season in the last five years the other is an economy in free fall absolute economic meltdown hyper inflation is a huge problem so it Jim Bob wins are hurting in so many ways I understand that for a few years now W. F. P. has been giving cash transfers to organizations and people in Zimbabwe meaning giving them money as opposed to sending in big sacks of food which I think we remember from the eighties and nineties but for the moment you are now shifting back in Zimbabwe to the big sacks of food rather than the cash can you tell me why the shift in strategy well there is very limited local currency available so that is in bad winds who we support are telling us please give us food please don't give us cash because cash becomes devalued so quickly I would imagine that one of the logistical benefits to cash transfers to just giving people money to buy food is that it's easier can you talk about the logistical complications of getting food into Zimbabwe and get than getting it distributed to those millions of people for sure because much of the rest of southern Africa has been hit hard by drugs and flooding this year and there is relatively limited amounts of food that we can procure in the region and on the continent so we are having to go to Latin America to Europe and Asia to procure the food commodities and that we need for Zimbabwe so it can take weeks or months to ship the man Zimbabwe is a landlocked country and so that food has to be shipped into courts in South Africa and Mozambique and then trucked into Zimbabwe given the factors that are at play here drought climate change hyper inflation how long do you imagine this crisis continuing and it looks like it will go on indefinitely the emergency operation and that we are undertaking it's a bandaid it's it's it's a short term fix what really needs to happen is that the vulnerable communities in Zimbabwe ARE helped to be able to withstand the impacts of climate change Mr Burke thank you so much for your time thank you very much Jerry Burke is a southern Africa spokesman for the world food program tuberculosis kills more people around the world than any other infectious disease there is a vaccine for it but it's not been entirely clear how effective the vaccine is researchers have now made a discovery it involves using the same vaccine but administering it in a different way NPR's peen Quang spoke to the scientists who made the break through the tuberculosis vaccine that exists now has been around for almost a hundred years it uses what's basically a form of how to Regulus is called BCG and Robert cedar a researcher at the national institutes of health so that really doesn't work very well it turns out that getting BGG hairs efficacy against pulmonary tuberculosis we we between say zero and eighty percent what do you do with that information it's currently limited use mostly given as a vaccine the babies and places where tuberculosis is common cedar wasn't satisfied with those numbers he thought it could work better so he and Joanne Flynn an immunologist at the university of Pittsburgh ran a study where they gave rhesus monkeys super high doses of the same old vaccine as an injection into the bloodstream six months later they expose the monkey see clouds of tuberculosis bacteria Flynn says when they saw the results we were stunned we were stunned and surprised they checked it again to make sure it was right it turns out that is true after three months nine out of ten monkeys are vaccinated in this new way were protected against the disease many showed no signs of the bacteria in their systems at all the results are published in the journal nature bill Jacobs a TV vaccine researcher at Albert Einstein college of medicine not affiliated with the study says the results are impressive I've been working on it for thirty years the entire field has never really seen sterilizing immunity before like what was seen in this animal study he says the study shows that it's possible to consistently prime it means systems to prevent a regular system factions the researchers are trying to figure out why it works so well friends is the best guess is that by loading the bloodstream with lots of bacteria they got key parts of the immune system to recognize it and then you have enough T. cells that are in the right place there in the lungs in order to fight off the infection to regulate this vaccine that's ninety percent effective would be a game changer every year at ten million people catch the disease and one point seven million people die from it so Jacobs says this is a ways off from being used in humans what they gave the Monkees was a high dose of live bacteria a hundred times more than the typical does right into the bloodstream it might not be safe for people especially those whose immune systems are compromised a lot more research will going to figuring out how it works Sir can some day.

Steve Inskeep U. N. NPR
"robert cedar" Discussed on KCRW

KCRW

07:34 min | 2 years ago

"robert cedar" Discussed on KCRW

"Creative people in affected institutions committed to building a more Joss verdant and peaceful world more information is that mac found dawdle it's six twenty two it's morning edition from NPR news I'm Steve Inskeep and I'm a well can good morning the U. N.'s world food program says eight million people in Zimbabwe don't have enough food to meet their basic daily needs that is half the country's population and the W. F. P. says it's a profound crisis Jerry Burke is a spokesman for the world food program he was in Zimbabwe last week and he told me what he saw there well it's a very very grim situation infected it's a national catastrophe nothing short of that eight million people half the population on the brink of starvation literally not knowing where the next meal is coming from so many families desperate hurting struggling they're skipping meals they're taking their kids out of school they're selling off what little they have by way of precious belongings family assets malnutrition rates are rising so it's an absolute disaster what what is behind this disaster well there are two principal contributing factors one is climate change Zimbabwe like much of the rest of southern Africa has had one normal rainy season in the last five years the other is an economy in free fall absolute economic meltdown hyper inflation is a huge problem so it Jim Bob wins are hurting in so many ways I understand that for a few years now WFP has been giving cash transfers to organizations and people in Zimbabwe meaning giving them money as opposed to sending in big sacks of food which I think we remember from the eighties and nineties but for the moment you are now shifting back in Zimbabwe to the big sacks of food rather than the cash can you tell me why the shift in strategy well there is very limited local currency available so that is in bad wins who we support are telling us please give us food please don't give us cash because cash becomes devalued so quickly I would imagine that one of the logistical benefits to cash transfers to just giving people money to buy food is that it's easier can you talk about the logistical complications of getting food into Zimbabwe and get than getting it distributed to those millions of people for sure because much of the rest of southern Africa has been hit hard by drought and flooding this year and there is relatively limited amounts of food that we can procure in the region and on the continent so we are having to go to Latin America to Europe and Asia to procure the food commodities and that we need for Zimbabwe so it can take weeks or months to ship the man Zimbabwe is a landlocked country and so that food has to be shipped into courts in South Africa and Mozambique and then trucked into Zimbabwe given the factors that are at play here drought climate change hyper inflation how long do you imagine this crisis continuing and it looks like it will go on indefinitely the emergency operation and that we are undertaking it's a bandaid it's it's it's a short term fix what really needs to happen is that the vulnerable communities in Zimbabwe ARE helped to be able to withstand the impacts of climate change Mr Burke thank you so much for your time thank you very much Jerry Burke is a southern Africa spokesman for the world food program tuberculosis kills more people around the world than any other infectious disease there is a vaccine for it but it's not been entirely clear how effective the vaccine is researchers have now made a discovery it involves using the same vaccine but administering it in a different way NPR's peen Quang spoke to the scientists who made the break through the tuberculosis vaccine that exists now has been around for almost a hundred years it uses what's basically a form of how to ridiculous is called BCG and Robert cedar a researcher at the national institutes of health so that really doesn't work very well it turns out that getting BCG has efficacy against pulmonary tuberculosis we we between say zero and eighty percent what do you do with that information it's currently limited use mostly given as a vaccine to babies and places where tuberculosis is common cedar wasn't satisfied with those numbers he thought it could work better so he and Joanne Flynn an immunologist at the university of Pittsburgh ran a study where they gave rhesus monkeys super high doses of the same old vaccine as an injection into the bloodstream six months later they expose the monkey see clouds of tuberculosis bacteria Flynn says when they saw the results we were stunned we were stunned and surprised they checked it again to make sure it was right it turns out that is true after three months nine out of ten monkeys are vaccinated in this new way were protected against the disease many showed no signs of the bacteria in their systems at all the results are published in the journal nature bill Jacobs a TV vaccine researcher at Albert Einstein college of medicine not affiliated with the study says the results are impressive I've been working on it for thirty years the entire field has never really seen sterilizing immunity before like what was seen in this animal study he says the study shows that it's possible to consistently prime it means systems to prevent a regular system factions the researchers are trying to figure out why it works so well friends is the best guess is that by loading the bloodstream with lots of bacteria they got key parts of the immune system to recognize it and then you have enough T. cells that are in the right place they're in the lungs in order to fight off the infection to regulate this vaccine that's ninety percent effective would be a game changer every year it's ten million people catch the disease and one point seven million people die from it still it Jacob says this is a ways off from being used in humans what they gave the Monkees was a high dose of live bacteria a hundred times more than the typical does right into the bloodstream it might not be safe for people especially those whose immune systems are compromised a lot more research will going to figuring out how it works Sir can some day lead to a safe vaccine for many humans ping Wong NPR news this is NPR news and you are listening to KCRW breaking news out this morning another Democrat is dropping out of the U. S. presidential race will have more coming up from NPR.

Joss verdant mac
"robert cedar" Discussed on WNYC 93.9 FM

WNYC 93.9 FM

03:23 min | 2 years ago

"robert cedar" Discussed on WNYC 93.9 FM

"Kills more people around the world than any other infectious disease there is a vaccine for it but it's not been entirely clear how effective the vaccine is researchers have now made a discovery it involves using the same vaccine but administering it in a different way NPR's peen Quang spoke to the scientists who made the break through the tuberculosis vaccine that exists now has been around for almost a hundred years it uses what's basically a form of how to Regulus is called BCG and Robert cedar a researcher at the national institutes of health so that really doesn't work very well it turns out that getting BCG has efficacy against pulmonary tuberculosis we we between say zero and eighty percent what do you do with that information it's currently limited use mostly given as a vaccine the babies and places where tuberculosis is common cedar wasn't satisfied with those numbers he thought it could work better so he and Joanne Flynn and immunologist at the university of Pittsburgh ran a study where they gave rhesus monkeys super high doses of the same old vaccine as an injection into the bloodstream six months later they expose the monkey see clouds of tuberculosis bacteria Flynn says when they saw the results we were stunned we were stunned and surprised the checked it again to make sure it was right it turns out that is true after three months nine out of ten monkeys are vaccinated in this new way were protected against the disease many showed no signs of the bacteria in their systems at all the results are published in the journal nature bill Jacobs a TV vaccine researcher at Albert Einstein college of medicine not affiliated with the study says the results are impressive I've been working on it for thirty years the entire field has never really seen sterilizing immunity before like what was seen in the sand will study she says the study shows that it's possible to consistently prime it means systems to prevent a regular system factions the researchers are trying to figure out why it works so well Flynn says the best guess is that by looting the bloodstream with lots of bacteria they got key parts of the immune system to recognize it and then you have enough T. cells that are in the right place there in the lungs in order to fight off the infection to regulate this vaccine that's ninety percent effective would be a game changer every year it's ten million people catch the disease and one point seven million people die from it so Jacobs says this is a ways off from being used in humans what they gave the Monkees was a high dose of live bacteria a hundred times more than the typical does right into the bloodstream it might not be safe for people especially those whose immune systems are compromised a lot more research will going to figuring out how it works Sir can some day lead to a safe vaccine for many humans along NPR news this is NPR.

"robert cedar" Discussed on KCRW

KCRW

03:23 min | 2 years ago

"robert cedar" Discussed on KCRW

"Kills more people around the world than any other infectious disease there is a vaccine for it but it's not been entirely clear how effective the vaccine is researchers have now made a discovery it involves using the same vaccine but administering it in a different way NPR's peen Quang spoke to the scientists who made the break through the tuberculosis vaccine that exists now has been around for almost a hundred years it uses what's basically a form of how to Regulus is called BCG and Robert cedar a researcher at the national institutes of health so that really doesn't work very well it turns out that getting BGG efficacy against pulmonary tuberculosis we we between say zero and eighty percent what do you do with that information it's currently limited use mostly given as a vaccine the babies and places where tuberculosis is common cedar wasn't satisfied with those numbers he thought it could work better so he and Joanne Flynn an immunologist at the university of Pittsburgh ran a study where they gave rhesus monkeys super high doses of the same old vaccine as an injection into the bloodstream six months later they expose the monkey see clouds of tuberculosis bacteria Flynn says when they saw the results we were stunned we were stunned and surprised they checked it again to make sure it was right it turns out that is true after three months nine out of ten monkeys are vaccinated in this new way were protected against the disease many showed no signs of the bacteria in their systems at all the results are published in the journal nature bill Jacobs a TV vaccine researcher at Albert Einstein college of medicine not affiliated with the study says the results are impressive I've been working on it for thirty years the entire field has never really seen sterilizing immunity before like what was seen in this animal study he says the study shows that it's possible to consistently prime it means systems to prevent a regular system factions the researchers are trying to figure out why it works so well Flynn says the best guess is that by loading the bloodstream with lots of bacteria they got key parts of the immune system to recognize it and then you have enough T. cells that are in the right place there in the lungs in order to fight off the infection to regulate this vaccine that's ninety percent effective would be a game changer every year it ten million people catch the disease and one point seven million people die from it so Jacobs says this is a ways off from being used in humans what they gave the Monkees was a high dose of live bacteria a hundred times more than the typical does right into the blood stream it might not be safe for people especially those whose immune systems are compromised a lot more research will going to figuring out how it works so can someday lead to a safe vaccine for many humans ping Wong NPR news this is NPR.

"robert cedar" Discussed on KQED Radio

KQED Radio

07:15 min | 2 years ago

"robert cedar" Discussed on KQED Radio

"Dot org it's morning edition from NPR news I'm Steve Inskeep and I'm a well can good morning the U. N.'s world food program says eight million people in Zimbabwe don't have enough food to meet their basic daily needs that is half the country's population and the W. F. P. says it's a profound crisis Jerry Burke is a spokesman for the world food program he was in Zimbabwe last week and he told me what he saw there well it's a very very grim situation infected it's a national catastrophe nothing short of that eight million people half the population on the brink of starvation literally not knowing where the next meal is coming from so many families desperate hurting struggling they're skipping meals they're taking their kids out of school they're selling off what little they have by way of precious belongings family assets malnutrition and rates are rising so it's an absolute disaster what what is behind this disaster well there are two principal contributing factors one is climate change Zimbabwe like much of the rest of southern Africa has had one normal rainy season in the last five years the other is an economy in free fall absolute economic meltdown hyper inflation is a huge problem so it Jim Bob wins are hurting in so many ways I understand that for a few years now W. F. P. has been giving cash transfers to organizations and people in Zimbabwe meaning giving them money as opposed to sending in big sacks of food which I think we remember from the eighties and nineties but for the moment you are now shifting back in Zimbabwe to the big sacks of food rather than the cash can you tell me why the shift in strategy well there is very limited local currency available so as in bad wins who we support telling us please give us food please don't give us cash because cash becomes devalued so quickly I would imagine that one of the logistical benefits to cash transfers to just giving people money to buy food is that it's easier can you talk about the logistical complications of getting food into Zimbabwe and get than getting it distributed to those millions of people for sure because much of the rest of southern Africa has been hit hard by drugs and flooding this year and there is relatively limited amounts of food that we can procure in the region and on the continent so we are having to go to Latin America to Europe and Asia to procure the food commodities and that we need for Zimbabwe so it can take weeks or months to ship the men Zimbabwe is a landlocked country and so that food has to be shipped into courts in South Africa and Mozambique and then trucked into Zimbabwe given the factors that are at play here drought climate change hyper inflation how long do you imagine this crisis continuing and it looks like it will go on indefinitely the emergency operation and that we are undertaking it's a bandaid it's it's it's a short term fix what really needs to happen is that the vulnerable communities in Zimbabwe ARE helped to be able to withstand the impacts of climate change Mr work thank you so much for your time thank you very much Jerry Burke is a southern Africa spokesman for the world food program and tuberculosis kills more people around the world than any other infectious disease there is a vaccine for it but it's not been entirely clear how effective the vaccine is researchers have now made a discovery it involves using the same vaccine but administering it in a different way NPR's peen Quang spoke to the scientists who made the break through the tuberculosis vaccine that exists now has been around for almost a hundred years it uses what's basically a form of cow tuberculous is called BCG and Robert cedar a researcher at the national institutes of health so that really doesn't work very well it turns out that getting BGG efficacy against pulmonary tuberculosis we we between say zero and eighty percent what do you do with that information it's currently limited use mostly given as a vaccine the babies and places where tuberculosis is common cedar wasn't satisfied with those numbers he thought it could work better so he and Joanne flan an immunologist at the university of Pittsburgh ran a study where they gave rhesus monkeys super high doses of the same old vaccine as an injection into the bloodstream six months later they expose the monkey see clouds of tuberculosis bacteria Flynn says when they saw the results we were stunned we were stunned and surprised they checked it again to make sure it was right it turns out that was true after three months nine out of ten monkeys are vaccinated in this new way were protected against the disease many showed no signs of the bacteria in their systems at all the results are published in the journal nature bill Jacobs a TV vaccine researcher at Albert Einstein college of medicine not affiliated with the study says the results are impressive I've been working on it for thirty years the entire field has never really seen sterilizing immunity before like what was seen in the sand will study she says the study shows that it's possible to consistently prime it means systems to prevent a regular system factions the researchers are trying to figure out why it works so well France is the best guess is that by loading the bloodstream with lots of bacteria they got key parts of the immune system to recognize that and then you have enough T. cells that are in the right place they're in the lungs in order to fight off the infection to regulate this vaccine that's ninety percent effective would be a game changer every year at ten million people catch the disease and one point seven million people die from it so Jacobs says this is a ways off from being used in humans what they gave the Monkees was a high dose of live bacteria a hundred times more than the typical does right into the bloodstream it might not be safe for people especially those whose immune systems are compromised a lot more research will going to figuring out how it works so we can someday lead to a safe vaccine for many humans ping Wong NPR news this is NPR news as inter Yang.

Steve Inskeep U. N. Dot NPR
"robert cedar" Discussed on WNYC 93.9 FM

WNYC 93.9 FM

07:08 min | 2 years ago

"robert cedar" Discussed on WNYC 93.9 FM

"N.'s world food program had been giving cash to eight million people in Zimbabwe who don't have enough food to meet their basic needs the WFP is taking an unusual step though and they're moving to food assistance instead drought climate change in inflation of cost a crisis in which half of the country's population is going hungry Jerry Burke is a spokesperson for the world food program he was in Zimbabwe last week and he told me what he saw there well it's a very very grim situation infected it's a national catastrophe nothing short of that eight million people half the population on the brink of starvation literally not knowing where the next meal is coming from so many families desperate hurting struggling they're skipping meals they're taking their kids out of school they're selling off what little they have by way of precious belongings family assets malnutrition rates are rising so it's an absolute disaster what what is behind this disaster well there are two principal contributing factors one is climate change Zimbabwe like much of the rest of southern Africa has had one normal rainy season in the last five years the other is an economy in free fall absolute economic meltdown hyper inflation is a huge problem so it Jim Babb wins are hurting in so many ways I understand that for a few years now WFP has been giving cash transfers to organizations and people in Zimbabwe meaning giving them money as opposed to sending in big sacks of food which I think we remember from the eighties and nineties but for the moment you are now shifting back in Zimbabwe to the big sacks of food rather than the cash can you tell me why this often strategy well there is very limited local currency available so es in Babb wins who we support are telling us please give us food please don't give us cash because cash becomes devalued so quickly I would imagine that one of the logistical benefits to cash transfers to just giving people money to buy food is that it's easier can you talk about the logistical complications of getting food into Zimbabwe and get than getting it distributed to those millions of people for sure because much of the rest of southern Africa has been hit hard by drugs and flooding this year and there is relatively limited amounts of food that we can procure in the region and on the continent so we are having to go to Latin America to Europe and Asia to procure the food commodities and that we need for Zimbabwe so it can take weeks or months to ship the man Zimbabwe is a landlocked country and so that food has to be shipped into courts in South Africa and Mozambique and then trucked into Zimbabwe given the factors that are at play here drought climate change hyper inflation how long do you imagine this crisis continuing and it looks like it will go on indefinitely the emergency operation and that we are undertaking it's a bandaid it's it's it's a short term fix what really needs to happen is that the vulnerable communities in Zimbabwe ARE helped to be able to withstand the impacts of climate change Mr Burke thank you so much for your time thank you very much Jerry Burke is the southern Africa spokesman for the world food program tuberculosis kills more people around the world than any other infectious disease there is a vaccine for it but it's not an entirely clear how effective it is researchers have now made a discovery that may be significant in involves using the same vaccine but administering it in a different way NPR's peen won't talk to the scientists who made brick who made the break through the tuberculosis vaccine that exists now has been around for almost a hundred years it uses what's basically a form of how to Regulus is called BCG and Robert cedar a researcher at the national institutes of health so that really doesn't work very well it turns out that getting BCG hard efficacy against pulmonary tuberculosis we we between zero and eighty percent what do you do with that information it's currently in limited use mostly given as a vaccine the babies and places where tuberculosis is common theater wasn't satisfied with those numbers he thought it could work better so he and Joanne Flynn an immunologist at the university of Pittsburgh ran a study where they gave rhesus monkeys super high doses of the same old vaccine as an injection into the bloodstream six months later they expose the monkey see clouds of tuberculosis bacteria Flynn says when they saw the results we were stunned we were stunned and surprised they checked it again to make sure it was right it turns out that is true after three months nine out of ten monkeys are vaccinated in this new way were protected against the disease many showed no signs of the bacteria in their systems at all the results are published in the journal nature bill Jacobs a TV vaccine researcher at Albert Einstein college of medicine not affiliated with the study says the results are impressive I've been working on it for thirty years the entire field has never really seen sterilizing immunity before like what was seen in the sand will study she says the study shows that it's possible to consistently prime it means systems to prevent a regular system factions the researchers are trying to figure out why it works so well friends is the best guess is that by looting the bloodstream with lots of bacteria they got key parts of the immune system to recognize it and then you have enough T. cells that are in the right place there in the lungs in order to fight off the infection to regulate this vaccine that's ninety percent effective would be a game changer every year it's ten million people catch the disease and one point seven million people die from it so Jacobs says this is a ways off from being used in humans what they gave the Monkees was a high dose of live bacteria a hundred times more than the typical does right into the blood stream it might not be safe for people especially those whose immune systems are compromised a lot more research will going to figuring out how it works Sir can some day lead to a safe vaccine for many humans ping Wong NPR news this is NPR news and you're listening to morning edition on W. M. my CD's headlines are just ahead.

N. Zimbabwe WFP
"robert cedar" Discussed on KNST AM 790

KNST AM 790

02:22 min | 2 years ago

"robert cedar" Discussed on KNST AM 790

"First I think we need to clear the air what do you mean I mean clear the air between me and you I think saying he likes me better than she likes you I stand corrected get guard dog protection for your air conditioner for just fourteen ninety five a month get a G. O. E. T. T. L. E. things quickly and we do things well brush fires consuming Australia's east coast showed no sign of slowing down Sidney mayor clover Moore was starting twenty twenty in a very somebody moved laws have been lost how's it been lost and crews discovered three more bodies Wednesday bringing the number killed the seventeen hundreds of animals of also died in the fire which destroyed more than one thousand homes and businesses Israeli prime minister Benjamin Netanyahu seeking immunity from prosecution in corruption cases at Yahoo will ask parliament to grant him immunity from corruption charges that could delay his trial until after elections in March Netanyahu is hoping to win a majority coalition that will shield him from prosecution essentially turning his election campaign into a referendum on whether he should remain in office or step down to stand trial boxes I should house name a new way to administer an old vaccine may be the key to a disease that has a scorching the third world instead of a needle in the upper arm what about a needle in a vain Dr Robert cedar of the national institutes of health came up with the idea of injecting the tuberculosis vaccine directly into the bloodstream intravenously the method is only been tested in monkeys thus far but it dramatically improved its effectiveness over the traditional skin deep shot scientists believe the T. cells used to fight off a TB infection to reach the logs quicker when the vaccine is carried through the bloodstream the potential issue was the relative difficulty of giving a vaccine intravenously compared with other methods charmer gaudy fox news and a Colorado town is conned out of one million dollars in a bridge construction scanned the Denver post reports that the town of eerie fell for the scam and sent the money meant for bridge construction to a fake account I'm Carmen Robertson this fox news our twenty twenty I heart radio podcast.

Australia prime minister Benjamin Netanyahu Yahoo Dr Robert cedar Carmen Robertson G. O. E. T. T. L. E. Sidney clover Moore tuberculosis Colorado Denver post
"robert cedar" Discussed on KTOK

KTOK

02:09 min | 2 years ago

"robert cedar" Discussed on KTOK

"Twenty America is watching brush fires consuming Australia's east coast showed no sign of slowing down Sidney mayor clover Moore was starting twenty twenty in a very somebody moved laws have been lost how's it been lost and crews discovered three more bodies Wednesday bringing the number killed the seventeen hundreds of animals of also died in the fire which destroyed more than one thousand homes and businesses Israeli prime minister Benjamin Netanyahu seeking immunity from prosecution in corruption cases at Yahoo will ask parliament to grant him immunity from corruption charges that could delay his trial until after elections in March Netanyahu is hoping to win a majority coalition that will shield him from prosecution a sensually turning his election campaign into a referendum on whether he should remain in office or step down to stand trial boxes I should because name a new way to administer an old vaccine may be the key to a disease that has a scorching the third world instead of a needle in the upper arm what about a needle in a vain Dr Robert cedar of the national institutes of health came up with the idea of injecting the tuberculosis vaccine directly into the bloodstream intravenously the method is only been tested in monkeys thus far but it dramatically improved its effectiveness over the traditional skin deep shot scientists believe the T. cells used to fight off a TB infection to reach the logs quicker when the vaccine is carried through the bloodstream the potential issue is the relative difficulty of giving a vaccine intravenously compared with other methods timer gaudy fox news and a Colorado town is conned out of one million dollars in a bridge construction scanned the Denver post reports that the town of eerie fell for the scam and sent the money meant for bridge construction to a fake account I'm Carmen Robertson this fox news by Travis Watkins tax IRS problems.

America Australia prime minister Benjamin Netanyahu Yahoo Dr Robert cedar Carmen Robertson Sidney clover Moore tuberculosis Colorado Denver post Travis Watkins IRS
"robert cedar" Discussed on AM 1350 WEZS

AM 1350 WEZS

02:18 min | 2 years ago

"robert cedar" Discussed on AM 1350 WEZS

"Twenty twenty six in your hands America is watching brush fires consuming Australia's east coast showed no sign of slowing down Sidney mayor clover Moore was starting twenty twenty in a very somber moved laws have been lost how's it been lost and crews discovered three more bodies Wednesday bringing the number killed the seventeen hundreds of animals of also died in the fire which destroyed more than one thousand homes and businesses Israeli prime minister Benjamin Netanyahu seeking immunity from prosecution in corruption cases Yahoo will ask parliament to grant him immunity from corruption charges that could delay his trial until after elections in March Netanyahu is hoping to win a majority coalition that will shield him from prosecution essentially turning his election campaign into a referendum on whether he should remain in office or step down to stand trial boxes on your house name a new way to administer an old vaccine may be the key to a disease that has a scorching the third world instead of a needle in the upper arm what about a needle in a vain Dr Robert cedar of the national institutes of health came up with the idea of injecting the tuberculosis vaccine directly into the bloodstream intravenously the method has only been tested in monkeys thus far but it dramatically improved its effectiveness over the traditional skin deep shot scientists believe the T. cells used to fight off a TB infection to reach the logs quicker when the vaccine is carried through the bloodstream the potential issue is the relative difficulty of giving a vaccine intravenously compared with other methods charmer gaudy fox news and a Colorado town is conned out of one million dollars in a bridge construction scanned the Denver post reports that the town of eerie fell for the scam and sent the money meant for bridge construction to a fake account I'm Carmen Robertson this fox news Hey y'all Jeff Foxworthy here now if you ever found yourself repeating the same thing over and over for seventy five years you might be Smokey.

America Australia prime minister Benjamin Netanyahu Yahoo Dr Robert cedar Carmen Robertson Jeff Foxworthy Sidney clover Moore tuberculosis Colorado Denver post
"robert cedar" Discussed on News Radio 920 AM

News Radio 920 AM

02:15 min | 2 years ago

"robert cedar" Discussed on News Radio 920 AM

"For what we believe we have the power to change the course of our every four years choice we do something most people across the globe three receive twenty twenty and is watching brush fires consuming Australia's east coast showed no sign of slowing down Sidney mayor clover Moore was starting twenty twenty in a very somber mood laws of being lost houses are being lost and cruise discover three more bodies Wednesday bringing the number killed the seventeen hundreds of animals of also died in the fire which destroyed more than one thousand homes and businesses Israeli prime minister Benjamin Netanyahu seeking immunity from prosecution in corruption cases at Yahoo will ask parliament to grant him immunity from corruption charges that could delay his trial until after elections in March Netanyahu is hoping to win a majority coalition that will shield him from prosecution essentially turning his election campaign into a referendum on whether he should remain in office or step down to stand trial boxes I suppose name a new way to administer an old vaccine may be the key to a disease that has a scorching the third world instead of a needle in the upper arm what about a needle in a vain Dr Robert cedar of the national institutes of health came up with the idea of injecting the tuberculosis vaccine directly into the bloodstream intravenously the method is only been tested in monkeys thus far but it dramatically improved its effectiveness over the traditional skin deep shot scientists believe the T. cells used to fight off a TB infection to reach the logs quicker when the vaccine is carried through the bloodstream the potential issue is the relative difficulty of giving a vaccine intravenously compared with other methods timer gaudy fox news and a Colorado town is conned out of one million dollars in a bridge construction scanned the Denver post reports that the town of eerie fell for the scam and sent the money meant for bridge construction to a fake account I'm Carmen Roberts.

Australia prime minister Benjamin Netanyahu Yahoo Dr Robert cedar Carmen Roberts Sidney clover Moore tuberculosis Colorado Denver post
"robert cedar" Discussed on WHAS 840 AM

WHAS 840 AM

02:11 min | 2 years ago

"robert cedar" Discussed on WHAS 840 AM

"Yes Sir staying and I mean I got like a commercial or anything but I thought he kind understated yes product my ten years ago I've got the cedar trail the house steel siding is Joe Roberts cedar tram and I've got you know a roster number dealers on it and the jacks are that explores but the the deck railings are are trying and she's got the product so that I use and they are one is a pain color and one is a cedar color even talk to the and that stuff goes on like water I mean it just goes on so fast and I get five years I get a good five years out of it and now I don't wait for this stuff the startling during you know gray or whether it be for ivory trade it I mean it just barely started is that right in ten years and the last time was about three years ago and it still looks like I just did it and we get your either at the foot of the marriages mountains we get we get characters from thirty below eighty five degrees and and the sign where it just be five hundred three the sun is very and chat and I'm just amazed that that product line is what well it's it's always a little tricky and I will I will say this it's always a little tricky to put a time stamp on how long these last it really is it has so much to do though I have to admit your conditions are brutal because it's in it's really is all about the sun and you got powerful son in Montana you know and yeah that plus the air can wow so that's that's tremendous but yeah day a humble guy I just stumbled on it I don't I.

Montana Joe Roberts five years ten years eighty five degrees three years
"robert cedar" Discussed on KLBJ 590AM

KLBJ 590AM

03:32 min | 2 years ago

"robert cedar" Discussed on KLBJ 590AM

"The next door neighbor's Pitbull disposal had under the fence and obviously that might optimal started putting its arms to the fence and Klein digging in pushing as hard as I could and it just popped right on through the through the fence and the little gap out there and went straight from my dog the saga of my dog it could turn into no and I got her and I went inside good move yeah the right move yeah here's will call animal control officer genet pada Guida speaking with KV twenty four news log giving us the authority to remove the dogs for a dog attacking and killing another and so the pit bull remains on the property the owners have had no comment to cave you twenty four but they did write an apology letter to their neighbor and in that letter I it simply said their dog just isn't animal friendly as I guess a reasoning as to why that happened sorry my dog doesn't like other dogs bad all right Robert cedar park ten twenty three welcome good morning how you doing Robert just fun thank you all yeah and the incident I was gardening and one day and heard of a woman about fifteen twenty yards away from the screen Joe stroller she had a dark too but was her legs had been wrapped around by the the rope because it was trying to get away from a pit bull it was a large pit bull on all my god I'm winning over there the the dog cat already at the woman she was holding the baby need already got nailed the stroller should know what to say that all over the store owner gave up on the dollar it happened very quickly yes by the time I got there I don't believe it's coming at me and what and I'm not exactly small ball not exactly large the time for gun into in instances like this I'm going do I have to you know I'm I'm bout to let my fist down the dog's throat no when I will get a profusely but at least talking suffocated while hold on its neck and it's going left and right trying to get my arms I'm going home yeah how did it end what did you do a number of the owner of course to a full block away change screen running out in order to whatever she felt the don't you have a cold in the malls you know drilling was June and and I'm just going to how do you think how did this I will get out what now twice before lunch is enormous Maryland almost into his body all chill wills foreman or they're called I don't know these things a lot that got you where you located to the the green all right Robert I gotcha I think a lot of people agree with you too that they they need to do more all right here the numbers five one two eight three six zero five nine two you can call us you can text as we've got the very latest news headlines coming up just ahead at ten thirty market Melinda newsradio K. L..

fifteen twenty yards one day