35 Burst results for "Relapse"
Study identifies first potential treatment for meth addiction
"Has come roaring back, and during the pandemic, it has grown even worse. Deaths from meth overdoses surged by roughly a third last year, but there is some good news for the first time, Researchers say they have found a medical treatment that helps some people trying to recover from meth addiction. The study was published today in the New England Journal of Medicine. NPR addiction correspondent Brian Mann reports Jessica Martinez started using meth when she earned money as a sex worker paying her way through college. Her life quickly unraveled. Oh, I was shooting up every day. Sometimes 2 to 3 times a day mess is incredibly toxic and incredibly addictive. Martinez, who works now helping others with meth addiction, says when she started her recovery two years ago, it was brutally hard, in part because there was no medical treatments to help with cravings and withdrawal for heroin users. There's nothing down there, Suboxone I just wonder why we haven't researched this drug yet, but research has been happening at clinics around the country. Doctors working with the National Institute of Drug Abuse found a combination of two drugs now tracks own and bupropion helped many of their patients avoid relapse. Peace progress on it's quite significant. Dr Nora Volkow Biz, the institute's director. She says the clinical trial found roughly one in nine patients who used these two drugs in combination saw significant improvement. That may not sound like a home run. But she says, for medications, treating mental health or addiction, that's a strong result. Well, cops says it appears the drugs work together to ease depression and cravings. I mean, we have started to help them that way. This is done. We'll leave them to achieve recovery again. Many patients weren't helped by this treatment, but because these two drugs are widely available for treating other medical conditions, Volkov expects doctors to begin trying the method even before it wins approval from the Food and Drug Administration. Right now, I'm in the moment that the paper is published. Doctors are going to be reading about it than may prescribed the medications off label to their patients. Dr. Laura Raise a psychologist researching medical treatments for meth addiction at U. C. L. A She says. Today's study, published in the New England Journal of Medicine, changes the landscape of meth treatment. So far, we have come up empty. So I believe that this finding this clinical trial really is a breakthrough in many ways, because there have been many, many failed trials. This new treatment arrives at a moment when meth overdoses are killing four times more Americans every year. Compared with the decade ago. Matthew Donahue with the Drug Enforcement Administration says the trend is fueled by a pipeline of cheap meth smuggled from Mexico. It's almost like methamphetamines form the sky right now. With the amount that's coming through the borders through boats on planes, Donahue says methods everywhere from the deep south to the Pacific Northwest. He thinks the lack of medical therapies has complicated efforts to curb demand. There's one more reason new treatment approaches to help people quit meth are desperately needed more methods being laced with another deadly drug, the synthetic opioid fentanyl. Last year in the U. S. Meth and Fentanyl together pushed overdose deaths to roughly 82,000 grim new record. Brian Mann NPR news
TG Therapeutics announces positive results for Multiple Sclerosis drug Ublituximab
"The next company. I wanna to talk about is t g therapeutics ticker symbol. Tgt ex and they're now trading in a market cap of five point five billion dollars and we heard some news at ashley and then we heard a huge readout. Come out on thursday or friday. I believe of this past week on their. Ms data so very exciting stuff and what. They showed us at ashes. That umbrella said plus tax which is their molecule combination. Which they call you to. They showed that. It's superior to open new tuesday mab. Plus chlorine useful in patients with treatment naive and relapsed and refractory chronic lymphocytic leukemia and they presented their full data set from the face three unity. Cll study and this is a follow onto the top line data that they showed in q. Two twenty twenty. So i'm just gonna blow up the data here and the the data they saw and i'm just took the most important headline that i thought. Is that the hazard gratiot from patients that receive youtube versus. Oh plus h l was zero point five four six so what that means is that they have the risk of not maintaining progression free survival in patients that took you to which is a huge improvement in response from the standard of care. So this is great news for the company. it's really the the best kind of outcome you could expect from a follow on data released to the top line data so i think this is absolutely going to allow them to get approval. Nc l. l. And if we go back to our non-hodgkin's lymphoma list here. This is an indolent non hodgkin's lymphoma and they or they're planning to submit the be. La for this molecule and to the fda soon
Progress Toward A Safer Psychedelic Drug To Treat Depression And Addiction
"There's growing evidence that psychedelic drugs can help people with mental health problems like addiction and depression. But these drugs also cause hallucinations and other dangerous side effects. So as NPR's Jon Hamilton reports, scientists are working to create safer alternatives. The drug ibogaine comes from the roots of a West African shrub. Small studies suggest it can reduce drug cravings and withdrawal symptoms. But David Olson of the University of California, Davis says using ibogaine is a treatment presents huge challenges. Ibogaine is like the Mount Everest of psychedelics. It causes hallucinations and potentially fatal heart problems. Also, it's really hard to make in large quantities. Olson in a team of researchers had a question. Can you take a really complex molecular structure like ibogaine and distill it down to its essential elements that give rise to the beneficial effects? Coulson's team started by giving the ibogaine molecules some nips and tucks be locked off the parts of the structure that gave rise to a lot of the deleterious effects and we left the part of the structure intact. It still was able to have anti addictive and anti depressant properties. The changes also left the substance that was easy to manufacture. The scientist named their creation tavern and tha Log or TV G, and they began testing it in rodents, including some binge drinking mice. Every single animal in the experiment. Reduce their consumption for alcohol, which was really, really surprising. TVG also helped rats that had been addicted to heroin, Olson says. Usually these rats relapse in response to light or sound cues they associate with the drug Tabernacle log is able to have this long lasting protective effect on heroin relapse. TVG also improved symptoms of depression in mice. All without producing any heart problems or behaviors associated with hallucination. Wilson, who has a financial stake in T B G, says drugs based on psychedelic substances have great potential because they work in a different way. They don't mask disease symptoms. Really designed to try to rewire the brain. The T B G results appear in the journal Nature, and it's still not clear whether they will hold up in people. But scientists not involved in the study say the approach has great potential. It's definitely promising it zah first step Gabriella Manzano is a researcher at well Cornell Medicine in New York and co author of a commentary on the T V G study. She says it suggest a way to make other psychedelic drugs safe enough to become mainstream options for treating psychiatric disorders. This provides a road map on how we could start tweaking these chemical compounds to make them very useful in the clinic. Keep the good parts get rid of the bad parts. It's still not known, though, whether getting rid of the bad parts will keep the drugs from being effective. Counter. Liston is an associate professor of neuroscience and psychiatry it while Cornell. One of the big questions in the field is is the hallucinogenic experience necessary for getting better. And there's some evidence both ways, Liston says. It's time to figure out what psychedelic drugs and they're triplets counterparts can really do for people with depression, addiction, PTSD and other disorders. Let's gather the data. Let's see what works. Let's make sure we understand the safety profile. But let's also be open to the possibility that these compounds could really help. A lot of people who need help. Listen, notes that one psychedelic ketamine has already been approved to treat depression. Jon Hamilton. NPR news
Covid 'raises new psychiatric disorders risk'
"Of a case of Cove ID is mental health problem. Oxford University's Paul Harrison found one in five covert survivors was diagnosed with a mental health disorder within three months. Communist catch anxiety disorders followed by depression. And then we also saw insomnia and adventure and some other rare conditions to it appears culvert triggered a relapse and those people with past mental health issues and triggered new problems in those patients with no psychiatric history.
Some coronavirus survivors develop depression, anxiety within months of diagnosis, study finds
"Who have recovered from the Corona virus may be left with lasting mental health issues. It's got the details on this CBS news correspondent Vicki Barker. Oxford University's Paul Harrison found one in five covert survivors was diagnosed with a mental health disorder. Within three months of this category, work anxiety disorders followed followed by by depression depression and and then then we we also also saw saw insomnia insomnia and and dementia dementia and and some some other other rare rare conditions conditions to to it it appears appears covet, covet, triggered triggered a a relapse relapse and and those those people people with with past past mental mental health health issues issues and triggered new problems in those patients with no psychiatric history. Vicky Parker, CBS News London Crash course
"relapse" Discussed on The Porn Reboot Podcast
"Reroute podcast. Where you get practical tips to gaining control over your porn or sex addiction. I'm your host. Jake ama's z. Certified sex and porn addiction recovery coach. Welcome to the episode today. We're going to speak briefly on relapse prevention planning. I'm sure that i've spoken about a couple of times. And the porn reboot podcast. But today i'm just going to give you the step by step on what to do when you realize that you are about to relapse so again. Just another reminder which i do throughout the podcast so you don't have to go searching for relapse prevention episode. They'll always be one coming up. You know maybe fifty episodes later so once you start experiencing the symptoms of relapse and again a gentle reminder brother that you're relapse the way reconsider it and we talk about it here is your relapse has already begun the moment that you start crossing boundaries and you let go of yourself care right that's the mindset that you want to have you don't want to wait for it to actually happen so always remember that but once you start experiencing different symptoms things like irritability a lot of tiredness lot of confusion and when you find that your judgement is a little cloudy early new reboot. You're not going to have the presence of mind to get control of yourself. And within two porn reboot system. We've created various things. Suggest make you realize that. Oh okay. I'm probably headed towards a relapse but the first thing you want to do regardless of what stage you find yourself in is you need to get control of yourself. You need to be able to clear a mind you need to be able to fix your judgments and this usually starts by literally sitting down and putting pen to paper it is not something you can do in your head Some of you try to do this. Try to gain control of yourself by sitting down. Maybe absorbing your breathing and trying to figure out what's happening but understand that you are clouded mentally. You have a lot of neuro chemicals which are affecting your emotions. I mean you might not really be able to identify what they are and sitting down and observing. Your thoughts is only sitting down and getting further caught up in all the things which are happening. So when you put pen to paper whatever excise or tool from our system which you choose to use what that does is that it pulls out one thing instead of leaving you in your head playing around with this soup of different emotions. Different thoughts i. Maybe you wanna do a basic rationally. Irrational thought excise like what all my irrational thoughts right now. You're rational thought. Might be just just one time won't hurt right or for some of you. Who might be listening to this in november and you'll following the culture you know the whole no fat on no not november. And you're like you know what it's november. Let me just slip and release this pressure. And i can just start from the beginning in november right or you deserve this. You've worked really hard. You stayed off pornography and masturbation for such a long time so you deserve to to do this or you're hit by a combo of things right. There's some issue in your relationship. You're a little bit sick. And you know your willpower. Is we this a few different things going on that. Bring up some irrational thoughts irrational beliefs while you have the opportunity to put pen to paper and write down. What all the different irrational thoughts and beliefs are. Sometimes you can just write out your feelings right. How do i feel other times. You can have a conversation pen to paper with that addict. Part of yourself right and so gaining control of yourself is the first thing you want to do. The next thing that you need to do is you need to actually assess yourself right so by assessing yourself means that once you've written out everything or some of the irrational things which are happening in your head. You want to find out where those thoughts are actually coming from and this might seem as you listen to my well. Jk that's that simple once. I do the holy rational rational thing or whatever else you said. Isn't that an assessment. Not really the purpose of that is to gain control of yourself by simply becoming aware or rather the more aware that you headed for relapse. The assessment itself is going to tell you how you actually got to this point the series of events that took place that got you to having an irrational thought or to feel a certain way. So what's going on in your life right. Maybe you have been. Let's mismanaging your time. Maybe you haven't been giving your relationship all the attention that it needs may be. You're having some financial issues. Whatever the case may be assess it and find out what's happening. Maybe your diet suddenly changed. Maybe moved to a new location. Maybe you got a hold of a new device which doesn't have a filter on it. Maybe you spent a lot of time focusing on the election and that's now affecting your emotions negatively so that's the next thing you want to do. You want to assess how you got to that point. The third thing to do is educate yourself. This means this is the perfect time to actually sit down and pull up something from your journal or from one of our courses all my videos or this podcast and educate yourself about what is actually happening to me for. The purpose of this is a win anna's but it is an awareness that has brought about from its external form of awareness. When you educate yourself on what is going on it calms you down. That's the reason why whenever you feel. You're having symptoms of some sort of health condition that you're not certain off. That's the reason why. I run to google and google like. Oh you know pain in my balls or or weird sore chest or whatever the case may be because we want something we want to educate ourselves on it so that we have a little bit more control and that is one of the reasons why education on this is very important in our groups. We have the men share to the group and let us know what's happening and they're going to get a combination of different things. You're going to get a brothers and group. Who are going to reach out and make sure that they're stabilized. We're going to have accountability partners while people remind them heyman. Have you spoken to your accountability partner. Have you called your ability partner. We have other guys who will help them. Assess you know in the comments section and then of course there are some that are going to also educate them but again all of this right now. If you're not in any of groups you can still do all these things on your on. Now at this point you've gained some measure of control over the relapse. But you're not done yet. The next thing you want to do. Is you want to identify what the warning signs are so that this doesn't happen in the future or so that you're aware it's about to happen in the future. Usually men will stop after they've assess themselves and after they've gained control over themselves and nothing else happens. But this is one of the reasons why you end up being caught in a cycle of relapse you keep relaxing for the same reasons over and over again and it gets very frustrating so going through the remaining things i'm talking about the remaining steps is how you actually plan to prevent relapses so back to identifying. What the warning signs were. What are the warning signs. It might be feeling unusually discombobulated. It might be not being able to focus on your work for heavy about half an hour. If you know it's like man. I can't focus and i took a break and i came back and i still can't focus. That could be a warning sign. Warning sign could be constantly distracting yourself. You're like man. I'm not really focusing on the task at hand. I keep searching for something. That's going to give me a little bit of dopamine right. I keep browsing through news. I keep hopping on instagram and different social media. Whatever the warning signs are for. You could be like. Oh i was alone you know. My wife left the house and she's gone for the weekend usually she's gone during the week or she's rally gone during the weekend and suddenly i feel like i need to do something. A warning sign could be being in a different environment. I like an environment where there were a lot of triggers. May be going to a bar going to party. Hang out with old friends and then you want to identify how you're going to actually manage those different warning signs. What are the things you're going to do in that situation. Okay my wife or my partner. I usually spend time with is away. And i have all this extra space that i don't know what to do with so next time this happens. I'm going to use this time to do this. Particular thing on this particular thing with this particular thing. That's an example. Or whenever i find myself with my friends and drinking. And i know that alcohol is a trigger. That leads to a relapse. Well i'm going to make sure that. I stick to a one or two drink minimum or set a timer on my watch us at a time and decide what i'm going to stop hanging out with them because they're all going to be a little bit drunk off to this point in time and the only option i have will be to drink to match level of an abbreviation. You guys know how it is after you've managed these warning signs. It is highly recommended that.
Working toward a new staging system for prostate cancer, and why it matters
"Doing some fascinating research. We have some new trials that we have ongoing and we're about to open some new ones. One that I'm very excited about for prostate cancer patients and those patients that have early stage prostate cancer that are considering our cyber knife program. Which we have ongoing that may need some hormonal therapy and instead of using the traditional hormones is a new hormonal agent. Now that we hope will spare men their potency in their erections in their testosterone level, and I'll be the lead investigator here for the GNU land going Enterprise. It will be open in the city as well as here on Long Island, and I hope to have that open in a few weeks. I'm very excited about that clinical trial. It's sponsored by the Dana Farber Cancer Institute. And I think will be the only center In the area That's going to be doing that, and we have some other trials as well. That will be talking about for those men with diagnosed with prostate cancer that have had a relapse of cancer using Very widely used medication called Met Foreman for diabetes, and our research has shown that There are certain receptors on the prostate cancer cells, thie insulin receptors. That, you know, has always been thought that maybe Sugar is involved in cancer growth. And if you can block the the sugar from entering into the cells, and it seems that made Foreman seems to do that. And prevent thes cancer cells from growing. This trial has been ongoing. It's up, it's up and running. And if you know of anyone that's already been treated for prostate cancer and Has had a relapse, meaning that there say is rising. Whether it be after surgery or after radiation than you can give us. Ah Ah call and be sure to Ah. You know, we have to evaluate the You know the individual, You know, it's a clinical trial. But
Kristen Bell opens up about husband Dax Shepard's relapse: 'I'll continue to stand by him'
"Her her husband, husband, Dax, Dax, Shepard's Shepard's battle battle with with addiction. addiction. I I will will continue continue to to stand stand by by him him because because he's he's very, very, very very worth worth Kristen Kristen Bell Bell standing standing by by her her man man speaking speaking to to Ellen Ellen de de generous generous about husband Dax, Shepard's recent confession that he had been using opioids. You're both so honest and Dax was recently honest about that he strayed from sobriety. Yes. How's he doing now? Is actually doing really great Shepherd, announcing that he'd relapse in his sobriety on his podcast late last month, saying he started to abuse painkillers following recent injuries for the last eight weeks. I'm on them all day in my addict, E brain. I'm doing all the dishes, and I'm being a dad And it's feeling very manageable Shepherd who's been sober for 16 years, confessing to the frozen star. Everybody's up against their own demons. Sometimes it's anxiety and depression. Sometimes it's substance abuse. And the thing I love most about Dax is a that he was able to tell me. And tell us and say We need a different plan right? Like we have a plan. If he gets it, if he has to take medication for any reason I have to administer it, But he was like, so we need a stronger plan. Belle telling Ellen that the two are now in therapy. One of the main reasons I love him is that he's also addicted to growth. He's addicted, Tio evolving and he was like I Don't want to risk this family and I did. So let's put you know new things in place to make sure it doesn't happen again, and we're going back to therapy. And I just I love that He's addicted to growth. And Kristen Bell, we're calling Dex tell her that he needed to do some of the emotional work to figure out what made him want to use again. Maybe sees Jenny Norman a 28 right now and it ABC
It's Time to Double Down on All That is Good!
"He's solar has its Lynn. Gosh I'm so sorry I left. y'All hanging last week Yep I went a little. Am I A and I'm going to tell you why a little sweaty this morning because I'm nervous and no, I haven't relapsed. There's nothing like that. It's more about what's happening in the United States of America where I live I know I have a lot of people listening who don't live in the country that I live in. So I'd be surprised if y'all hadn't heard about what happened last night and that is our first presidential debate. As we? Go into the final weeks before we vote for the president of the United, states don't worry I'm not going to get all political here. What I want to talk about today is how it is affecting this stuff that's going on in two thousand and twenty all of it including the race relations and Covid nineteen and the economy and what seems to be a little bit of a problem with our democracy in the united. States how it's affecting me, and that's why I'm a little nervous because I want to share with you what I've been going through in the hopes that we can all get through this together. So going back to last week, I have not been sleeping well, I. Think I've mentioned this a couple of times on previous podcast in the later months of the summer, but it's really been a combination I think of what's been happening. You know with everybody in the United States in the world around Cova da and uncertainty, but it's really gotten to be a peak for me because. I am frustrated and I'm not sure what to do with all of this Energy Aka frustration as I explained before in previous episodes I, know a lot of it has come from or at least not a lot of it but some of it has come from where I live. So I know I have control over that I'm changing that up I'm really excited about the move that I'm making to this wonderful development and a new place to set as my home, my home base a that's not all of it. The conundrum, which by the way isn't that a great word. Gosh. Okay. As an aside, it was also one of my favorite wines that I used to drink long ago just to get that out there the conundrum that I'm dealing with right now is okay what's going on with me in terms of how I'm feeling about all of this sustained uncertainty and damn what can I do about it? Like many of you I'm tired of this really really tired of not knowing the right steps to take who look for for leadership who to believe you know what to do in my day to make it more effective for me to stay healthy it just seems. Like one big mess, I am truly tired of having conversations with people that end in dispute not because we don't like each other because we have different values and different ideals of the world. All of that is okay. I know how to make boundaries around that. But Damn it's been really difficult this year because we're getting slammed with. So much of it. It being choices that we have to make day in and day out without any real guidance exhausting it's fatigue it's overwhelm and we have to figure out how to get back up from this we really do and I don't mean to sound like. Old Nineteen eighties. Cheerleader Lynn at all, that's not who wanna be for this podcast. Really. Not who I want to be in life anymore when I'm looking at to help me is to dig deep. To figure out how am I gonNA lift myself out of this conundrum this tricky confusing and difficult problem that I find myself
First man cured of HIV has died of cancer
"The first person known to have been cured of HIV has died from cancer. CBS News correspondent Elaine Cob reports from Paris made history in 2007 as the Berlin patient when a unique type of bone marrow transplant cured him of HIV. Timothy Ray Brown's experimental treatment was risky and expensive. Thie American remained a staunch advocate for the search for a more accessible HIV cure. He also had acute myeloid leukemia. That's what prompted the transplant. Brown suffered a relapse of the leukemia this year. His partner today announced his death. He was 54. Elaine, called CBS News.
Rebecca Hart: new solo mother, small business owner
"So I own a yarn store in cary North Carolina our Surrey's Lip I've owned the store for a little over eight years now, and I have a seven month old girl Miriam. Who is now sleeping in the store in the little makeshift bedroom for her? Yeah how does how does that work? So you just bring her in with you and you do have pretty normal stores now or how how does that work not quite and were playing around with the hours right now. But obviously because of Covid we're doing appointment only we're about to shift that, but typically I'm here. Five or six days a week. At, least like ten till three sometimes I do work after the. War It really depends on what's going on store and her schedule Times. She wakes up earlier or later. So, I do have a little bit of flexibility to cove it. I don't know if that's good or bad but. But yeah it's it's been. It's been interesting. So she just comes in naps there are hangs out with you while you're. Here early enough. So she can be down for her I. NAP. Anywhere between nine and ten, usually she goes down at and that's where I usually am able to get a good chunk of work done for a couple of hours whether have customers in or I'm doing work on my computer. So yes, she is fantastic a taking early nap and I really take advantage of that. Afterwards it's really hit or miss whether she's able to play in her little play yard independently, which is not for log or I throw or on my back, which is a new thing I've been doing and we're her or. I have in my lap and I try to take with her relapse. So tell us about warm and fuzzy yarn like why where did the idea for this business come to be and I assume that you must have been the crafty sister growing up if this? Maybe, take take our listeners through the journey of like how you made the choice with your career. Take really big and kind of risky stuff and like kind of with that thought process was like. And just kind of the bravery while I mean it's hard to to your own horn, but it was a very brave stop so. Tau Tell a little bit about that yet. So I had been working at a corporate job before for eight years, and now it's hard to believe that have actually been at the store now longer than the CIA which is amazing. But I was doing business eggs of doing. So a spreadsheet work during a computer all day long. Part of me liked what I was doing another part like hated just corporate of aspect of edge and I was just I felt like I hit a wall and just was brainstorming things to do and I kept coming back to yarn because that was always something like after work I remember driving to a yarn store in picking up yard and it was it was the highlight of my day and join know what exactly when it came into my head. I took a couple business trips down to Arlington, and nearby in Alexandria is a wonderful store. Named Fiber Space and they had just tons and tons of hand yard and each time I went. I, couple of hundred dollars on yard, which is pretty easy to do and I remember just feeling that that type of really was not available in the area or very, very limited. So I thought about that in at some point, I just. Wondered about how feasible it would be so I took a business class at night after work and handed amazing adviser helped me write a business plan feasibility studies in talked a lot. My friends were niggers and shares actually I was more of a crocheter when I started I got obsessed into knitting, which is more popular. Now, most of my customers and little by little, it somehow didn't seem impossible I needed to get my elsie license I needed to get. The finest space in have fire check, and it was just one thing after another and about a year after I started researching was opening my doors. and. So you sell. Tell us mean for those of us who are not yarn connoisseurs the hand I'd yarn is like the high end of the market right for people who are very particular about their sort of knitting. Yeah I mean there's hand died and there's also just a small scale production so. Pretty much all of my suppliers they're either one or two percents show or it's one of my brands that I love everything is sourced in a us from the actual wool the sheep event, it's died and a spun everything is done in the Uso just a lot of very very small-scale partners and it just makes it special. That's kind of exciting that the sheep are American citizens to.
Dax Shepard reveals he relapsed after 16 years of sobriety
"And his 16 years of sobriety, And now he's opening up about a relapse on his armchair expert podcast. He revealed that he's been taking Vicodin for about two months. Motorcycle accident August led him to taking pills every day. Says as a Friday he's 11 days sober, thanks to help from his wife, Kristen Bell and podcast co host Monica Badman. Jason Nathan's an ABC News Hollywood. Common is learning that Kobe Bryant's widow has filed a lawsuit against the Los
Dax Shepard reveals he relapsed after 16 years of sobriety
"Of Hollywood's more powerful couples having some challenges. Here's Jason, actor, director and podcast toast. Dax, Shepard has been very honest about his battles with addiction and his 16 years of sobriety, and now he's opening up about a relapse on his armchair expert podcast. He revealed that he's been taking Vicodin for about two months. Motorcycle accident August led him to taking pills every day. Says as a Friday he's 11 days sober, thanks to help from his wife, Kristen Bell and podcast co host Monica Badman.
Dax Shepard reveals he relapsed after 16 years of sobriety
"With addiction, actor director and podcast toast Dax, Shepard has been very honest about his battles with addiction and his 16 years of sobriety, and now he's opening up the butter relapse on his armchair expert podcast. He revealed that he's been taking Vicodin for about two months. Motorcycle accident August led him to taking pills every day, he says as a Friday 11 days sober, thanks to help from his wife, Kristen Bell and Podcast co host Monica Badman, Jason Nathan's an ABC News Hollywood and some good
Speeding the Delivery of CAR-T Therapies While Cutting the Cost
"Greg. Thanks for joining US getting so much standing. My pleasure. We're GONNA talk about Cartesian therapies, exuma biotech, and your efforts to develop rapid point of care delivery of these therapies. Let's start with Cartesian therapies themselves out of these therapies work today. Well you know if we were to look at this technology today. And put it in the context of what we do in science and medicine even fifteen years ago. The the thought that we could truly have living medicine with genetically modified. LYMPHOCYTES in the body would have been unheard of it. And really I think the basic process of taking one cells from the body. In reprogramming genetically lymphocytes in returning them back into a patient to retrain those cells to see cancer antigens much in the same way we've done with monoclonal antibodies in the past, but wiring all that into itself is what is made Carta. Medicine which has been both exciting in is of course had. Equally that the number of challenges in in many different areas. Well. How are these therapies typically prepared and administered? Well it's a complicated process that has. A tremendous amount of technical skill required as well as logistics so typically. When a subject is entering into a trial or on therapy for approved medicines, their blood is drawn and separated into white blood cells and then shipped usually on a plane to a central manufacturing facility where those cells then are taken into a cleanroom, they are activated their genetically modified they're grown for about. Fifteen days, and then they are prepared just like you would with drug. And then ship back to the site. So there's a tremendous amount of time that can be lost for patients during this period and then once those cells. Are received. Back The patient receives Olympic depleting chemotherapy regimen to kind of make space. And then the cells are infused and at that point they take off and they're on their own. These cell therapies have been more successful in hematological answers than in solid tumors. What why is that? Well I. Think if you look at the history of the Field Dang, what you will find is that. One of the principal challenges in building cellular therapies has been it. They can be incredibly potent. So in the case of something, we know very well like CD nineteen, this isn't a liquid tumor setting those cells with CD nineteen will eliminate. All targets in the body that express CD nineteen, and this is found in many lymphomas. leukaemias. But the problem is in the case of CD nineteen, you're eliminating all of the normal cells make CD nineteen, which are called E. Cells, and this is tolerable in the case of liquid tumors. But when you think about the antigens targets that we go after in solid tumors, those are often expressed in tissues that. Not Be safe if the immune system were to attack it. So we've been forced to really take steps back on how well we can make a car for solid tumors to try and make them smarter to help recognize friend from foe. So the great efficacy I think that you've seen in relapse refractory ael l.. As well as in diffuse large B. Cell Lymphoma, and now also I think exciting we in places like multiple myeloma getting that stain level of efficacy in solid tumors has required that people really think about the precision inside of the problem to make sure can get a potent car but also one that is safe.
Amelia Gray Hamlin says doctor warned she would be dead in 4 months from eating disorder
"Amelia Grey, Hamlin says her battle with anorexia almost took her life. Lisa Rinna errors and Rina's Excuse me, at least that rendition A 19 year old daughter first told fans that she was recovering from an eating disorder two years ago and said yesterday that the doctor overseeing her recovery only gave her months to live because of how bad her health wass Pamela has previously said that she believes she would've relapse that she not gone public with her battle.
Happy Soberversary! Lessons from 10 Years Sober & 12 Years in Recovery
"Hi sober souls. It's Lynn from Georgia and I'm really excited for today's episode because. I'm about to turn ten years summer. By the time you'll be listening to this. It will be July twenty seven. Which is my sober bursary? It is the day that I entered Hazelton Betty Ford in center city Minnesota, screaming. Yeah literally screaming for help. I was intoxicated so sometimes. I actually tell folks like I'm going to tell you that. My actual date of not being intoxicated was probably closer to the twenty eight, but I went in pretty early on the twenty seven. So it's just easier for me to remember. However I did spend twenty four hours in detox, which was super. Fun For those of you who have been? been through detox, it was my third detox and Yeah, that one stuck for those of you. Who May Not Know My story? I attempted to get sober like so many of us long before. I actually attained sobriety, so I say that I have been in recovery. 'cause, that's what I fully believe as opposed to one hundred percent sober for two years prior to actually finding sobriety. And they'll talk a little bit more about that once I. Get into what I'm going to share with. And that is my lessons from ten years of Sobriety in twelve years in recovery I've worked really hard to kind of home down to ten lessons. Only because it's fun to do it that way, Ten and ten you know, but there are so many more than ten lessons. Many of which I often talk about here on the PODCAST, so getting back to my story I was really bad off before I went into -ment and by bad off. I mean yeah, in the two years prior I had seven months of sobriety or I guess I would actually call it. Since I was still taking prescription drugs and counter drugs, not as prescribed, but leading up to my final days as an active drinker, I experienced loss, and what we often call in the Biz a precipitating event, which set my final days of drinking into high gear for approximately the final three months for me, and that event was my father died I was estranged from my father at the time. I actually felt like while he was dying, he was somewhat haunting me. And I would go between him haunting me about actually coming to see him before he died, my parents were living in Arizona at the time, and also just the culmination of his mental illness, which was lifelong for me in how that manifested in my waking and sleeping hours as negative self talk, and also I really did feel like he was in my consciousness. So hopefully that is okay for some of you out there indefinitely I know it's okay for those of us like myself. Who are into the Woohoo? So in any case he did pass away and for the next several weeks I was off and on drinking, and then well into the month of June where I had. Had really relapsed. If you will in a hard core way I just gave up, and I just started drinking twenty four seven, I would have days where I would push myself to recover, which meant for me sitting on my sofa until the nausea went away until I had stopped throwing up, and I would push myself into overdrive an exercise I would try and exercise and Excise the alcohol out of me, and it was so painful, and then of course after a day or so of doing this, I would talk myself into drinking again as if I could have some modicum of control, these were the days that I would wake up after only buying one bottle it was. At the time, which was so horrific to me that that's what I was buying, but that's what I was buying and I would go four blocks drive for blocks to the gas station to get it every morning. There were mornings that I was up at you. Know seven, because, of course you don't sleep well and rain for eight o'clock living in Wisconsin at the time for the store to open, so I could get my drug. It was excruciating. I was of course in a deep depression I wasn't thinking straight. I was isolating and there was literally nothing. Nothing, that anyone could do I at one point scheduled. What I know now is my second or third intervention. Call my family to come. Help me somehow, and they did not have any idea what to do. They were not well-versed in addiction at all. All they knew to do is to take me to the hospital. Where they gave me comfort drugs including Atta van and sent me home with Clemson
The danger of herd immunity in solving the COVID-19 problem
"Herd immunity, and it's a concept some leaders and scientists have considered when it comes to responding to this pandemic. NPR's Jeff Broomfield reports on what exactly this idea is and why it presents troubles. The thinking goes like this. Sooner or later, the pandemic cast stand and Debbie shredder gets it like everyone wants a way out psychologically right, because no one's ever coped with something of this scale, and it's not like a crisis like a hurricane or 9 11 where it's like, time bound or geographically bound. This is like everyone everywhere for indefinitely right now appeals to people, right? Treaters of researcher at the University of Edinburgh Medical School in the UK, and it turns out there is a theoretical way it could end. If enough people get sick and recover and they become immune to the corona virus. Then the pandemic fizzles. Those who haven't gotten it yet are safe. The technical name for this is herd immunity in its purest form. It's like Darwinian self selection, right? We let the virus go. Whoever is going to die, I will die. That's life and then whoever makes it we'll have hopefully some form of immunity. Several governments tried with the idea of the beginning of the pandemic, including the U. K, But in the end, most decided it would cost too many lives. There was one exception Sweden. They kept businesses open and let people make their own choices. At one point, Swedish officials said Stockholm would returned immunity by the end of May, but they have not reached it by the end of May. They just lost a lot of lives and also took an economic it shredder says. Herd immunity works as a math problem, but at an individual level Swedes stayed home. People don't want to catch Cove it nobody wants to be part of the herd to stay that way. But could nations eventually reach herd immunity more slowly? Probably not, says Jeffrey Shaymen of Columbia University. So example, I like to think about it. South Korea. They're getting 50 cases a day right now. They will hold on for another 1000 days, which is almost three years that have 50,000 cases, which is 30.1% of their population. Most experts think herd immunity take somewhere between 50 to 80% of the population, even in the U. S. Even it's 60,000 cases a day. It'll take at least into 2021 possibly years more to reach those levels. And there's another looming problem. People may be able to get the Corona virus more than once, shame and has studied other Corona viruses that cause common colds, and he found people could be re infected. Some of them were 48 weeks separated from the previous infection, which is rapid and that might have been a relapse. But others we clearly know are different. They were 8 to 11 months apart. Greta Bauer is an epidemiologist at Western University in Ontario, she says this fall and winter maybe the time we find out about re infections, and if Covitz survivors get even mildly sick, the second time around Corona virus will keep circulating. If that were the situation, then there's no potential to develop a level of herd immunity sufficient to stop the infection. I corresponded with 16 different scientists, and almost all believed that achieving herd immunity as a practical matter was virtually impossible. Without a vaccine with the vaccine. It will be a lot easier to control the virus, but it will likely still exist in pockets around the world. So what's going to happen again? Researcher devilish reader I think it's going to be with us play forever. At this point, I think I mean at a global scale, it's going to be with us, and it's how we decide to live with it. There are ways to live with it. Test the sick, isolate them until they're better and everybody where a mask and keep their distance.
These 3 Things Will Change Your Recovery
"Okay, we made it. That's it. Thank you for being patient to all the announcements I know it can get annoying especially when I'm talking about stuff. You are interested in, but remember other people are interested and we want serve everywhere, and you make sure there's something for everyone. Now, let's jump into this relapse roller coaster. My top three reasons people get stuck on the roller coaster. One expectations. You think it's going to be quick and easy to lack of direction you don't plan or create a toolbox or have support or three escape. You think you're craving drink, but really you're craving escape. That's a big one. So. Let's start with number one expectations. One of my favorite sayings is expectations are premeditated resentments. In the more you think about this phrase in different situations, the more you realize how accurate it is. It can be as simple as I walk into my regular AA meeting and I see someone there, and immediately in my head I create this expectation of how they're going to greet me. This is a split second thing that happens in my head. It flashes this picture of my friend being super happy to see me coming across the room to say hello or give me a hug and it's going to be all happy. But what happens is my friend is in the middle of a conversation with someone else. It just gives me a slight wave from across the room. We're all of a sudden. The committee kicks in and starts talking trash right. Do they not like me? Anymore I thought they'd come over and be happy to see me, did I do something wrong, did I do something to make the mad and I'll start going over in my head all the conversations we've had to see if there's some reason they don't like me anymore. Like, legit do this. The truth is the situation. Is there just in the middle of a conversation and didn't have time to come over before the meeting started. This can also get much more complicated, and it can completely derail your best intentions for example. You have an expectation that as soon as you quit drinking, your life is going to get easy in your problems. We'll start to disappear. When you have this expectation, you stop drinking and you get irritated when it doesn't feel easy because you thought alcohol was the problem. Here's a truth bomb. Alcohol and drugs are a symptom of the problem. The problem is we don't understand or cope with feelings well, so we use substances to numb the feelings, so we don't have to feel them. The reality is you drink to manipulate feelings. Dodge responsibility so when you quit drinking. All those habits don't magically disappear. Then you get mad because you thought putting down. The drink was going to solve your problems, but in truth it's just the tip of the iceberg. I'll give you another example for myself and how I get caught in the same trap. Many of you know about five years ago. I gained some weight in my eating. Habits got way out of control so for the past five years. I have been on the roller coaster with weight and food. And I've always fluctuated. Wait a little bit like five or seven pounds in as a younger person, I drop those few extra pounds super easy with little effort, but this time I gained twenty pounds, and now I'm forty eight. The weight doesn't just fall off like it did when I was twenty five, so I would get serious about losing the weight and changing my habits to eat healthier and start going to the gym, and when I didn't have big results in a week. I would get mad and depressed and say F. it. Because I had this expectation that I was going to work hard for five minutes and get results, but it doesn't work that way. It took me about a year to put on those twenty pounds so now I look at it as a long term, healing process that it should take me a year to heal change my lifestyle change my mindset to support the healthier lifestyle I want. That's how I want you to look at your recovery. This is a long game, not quick or instant results you are healing. You are changing lifestyle habits in retraining your brain to have a positive and healthy mindset. You know the person you want to be in the life you. WanNa have in. That isn't going to magically appear just because you put down your bottle of wine. It takes work it takes time. Now that. I've
"relapse" Discussed on Addiction Unlimited Podcast | Alcoholism | 12 Steps | Living Sober | Addiction Treatment
"List of actions on Your Action Plan in twenty percent of those are going to take you the next level. Figure out what you're twenty percent is right now. Where does your focus needs to be right now? What part of your recovery? Do, you need to focus on building your tribe. Then put your energy into that. Maybe you need to get your head right. Get rid of negativity, so put your focus into that. Just know that your. List needs a lot of tools on it, and those tools will play together in different. Ones will be more important at different times, but the point is not to do all of them every single day. Okay I. Hear this a lot. People will tell me like their morning routine or their workout plan, and it's this extensive thing that would be overwhelming for the most disciplined person on the planet. It's definitely too much for an undisciplined alcoholic right I have a long list of actions and prioritize which things are most important to you right now. In this moment and focus their. Don't try to have a morning routine that takes two hours with fifteen actions. It's not sustainable. You could do it for a while, but remember we're going for consistency, and that's next consistency. You Change Your whole life in ten to fifteen minutes a day, not because you're doing twenty things and doing them perfectly, but because you've made a commitment to show up for yourself every single day for ten to fifteen minutes at a time. And that's going to get you way farther than the hit and miss making plan and only showing up once a week or once a month, or you know doing your plan. You do it great for ten days, and then you fall often. Don't do it at all, right. Consistency! Commit consistently and show up. Last protect yourself. One of my greatest keys to success is understanding. My limitations are have to know how to work around that things that I'm not great at I. Have To hire people to do that stuff for I've I've to figure out a life hack to make things simple in achievable I have to ask for help when I need it. I have to love me and protect me because nobody else will do it as well as me. I am not anyone else's responsibility. I'm mine. So i. have to have boundaries. I have to be willing to walk away from some activities. I have to make sure I don't put myself in situations. I don't want to be in. Okay. How's that? How do we do? That's a lot of good information to make sure you're doing the right things moving the right direction to feed your recovery instead of Feeding Your Addiction You don't have to relapse. It doesn't have to be part of your story. It doesn't have to be part of your story anymore..
"relapse" Discussed on SOBER Swagg LIFE
"She moved in with me and she stayed with me and that meant that was meant a lot but she she is my my motherly figure and my mom told me yesterday maybe two days ago now that they were looking for earnings for and casket and I couldn't even stop by and give her a hug excuse my language, but that kind of Pisses me off because I absolutely want to go give that lady a hug. I'm living outside right now and I got two days sober now two days. I'm back to two days. I'm I'm going through the shakes. I'm doing the withdrawal I thing outside in a not healthy environment with but hey, it is what it is. I I wrote it myself and I'll continue to be a hundred percent honest with you guys because I Honestly, I don't care if anybody listens, but if people do listen then maybe somebody would realise that way. The struggle is real. You're not the only one going through it. like this struggle is it's real and it's I don't want to go detox get on might have to. Because I'm going to the shapes and because I'm going to the withdrawals, but I don't want to the the thirty-nine-year-old gentleman said he was sober he said after I walked there for a week, then he'll come pick me up and give me a ride that's incentive. That one's me just prove that I can do it. Not not just to him but to myself because we we all sort of delicious roll with everybody has some type of addiction or some type of something that holds you back. Yeah, I I can have a pity party and say I lost my job. I was the number one salesperson in their company history. I got the email that said I broke the record their best week ever was twenty-three leads. I put my first full week. I worked put up 26 in my second full week. I put a 31 so I I did do that..
"relapse" Discussed on SOBER Swagg LIFE
"Because I'm an alcoholic. I don't know if it's just me in particular or other alcoholics as well. But it seems like the common thing is is when I set my mind to doing something I can do it whether it's positive or whether it's negative and it's it seems to be a common theme. I hear in meetings in the rooms. I hear when associating with other alcoholics outside of the meetings just in general seems like addicts have more drive or more focus on something when they do it. Now that definitely hinder home and my drinking career because I was going to be the best alcoholic that I could be. I was going to be the one that drank the most I was going to be the last song To go to bed. I was just Making sure that whatever I did referring to alcohol I did it the best of my level. So today I'm telling you about how relapse and and how it has affected. I I saw a study earlier today over 40% of people that have less than a year of recovery relapsed. What? Yes, I I relapsed. And I hear recently. I've been to detox four times in the last three weeks two and a half weeks and I thought this coronavirus it it's not a joke. Like it it took it took my job away from me. It took my gym away from me. It took my meetings away from me it it took all my coping skills that I had compiled together. And now hey, I'm sleeping out here underneath the piece of wood and a tarp and some slugs like That's a struggle. That's a struggle right there. But you know what? The one thing I will never lose is my faith in a one thing. I always have with me is that nine and a half months that I had sober that's staying with me. I may I may have lost my sobriety date but I didn't lose those nine and half months and effort and everything that I learned in that process now, it's a month to process to try to get that back again. And right now what I'm struggling with is.
"relapse" Discussed on The Porn Reboot Podcast
"Many many many men focused on. How much worn a how many times they masturbated during the slip right on? It was so bad bro. I went right right back to the stuff that I didn't watch for four months. A cat believe it. I thought my brain was supposed to rewire. How could I go back to that nasty? Asked he stuff. It's like nothing changed in. Oh my God dude. I jerked off like seven times today and I woke up in the morning and I did it some more when you think this way this takes away from the impact of the moments. You crossed your boundary that first time you edge that first time you you basically touched yourself without ejaculated in the shower or in bed when you could sleep that first porn see that you watch for a few seconds then turned handed off now. That brothers was the moment that changed everything that was the catalyst for your mental relapse. Now your thoughts were. I'm not obsessive until you decided to take specific action. Such as looking at something explicit or edgy and the biggest mistake your logical mind base. Your Watch mine is yours your biggest enemy this entire thing. You that the biggest mistake it makes while trying to prevent a relapse is thinking that preventing a relapse is as simple as saying no right before. You're about masturbate ejaculate or watching basically your logical mind somehow convinces you over and over again. year-in-year-out ear out than last minutes. You can stop yourself. I can view some form. But I'll see no right before I decide to masturbate S- I can view some porn and I can edge but I'll say no right before I orgasm right. You're always wrong and so good convincing you. Otherwise Ray you could be right in every aspect of your life. Your logical mind keeps lying's you right and unfortunately those those moments right the moment right before you abouts masturbate before you Jackie late when you're edging those are the most difficult times to stop so true. Relapse prevention involves preventing yourself from ever getting to the point of emotional mental physical relapse brothers and that is where a system comes in and one of the most common statements which is made by my clients. Wendy in the first reach outs me as they say something along the lines of Jake. Hey listen man like I can't connect with my kids. My wife loves me and there is so much guilt because because she does not know who I am they don't have the hardest share it with her dude. I am depressed. I am dealing with all sorts of stress in my life always always takes me back to the novelty and I'm afraid that I've crossed the line among afraid that I can. I can never control this behavior right so men say think I never want to even think about viewing pornography ever again. I never want to think thank you doing porn ever again now. You feel that by thinking about pornography you are not truly rebooting and this is not true thinking about novelty and masturbating is a normal part of your reboots you cannot in raise your memories of pornography by raising and Yukon magically erased them or do some hypnosis thing any race them with the right tools and systems you can control kroll these thoughts until your brain rewires and you no longer crave the experience when you stop craving craving and experience a lot of the memories associated with that just kind of fade into the background. Because it's no longer something something that you're craving so that's it my brothers the three stages of relapse a little piece of one of the tools in the porn reboot SISTA STA called the relapse prevention amplifier. To so I hope you found this helpful. I'm Jay Jay your brother the struggle. Thank you so much much for taking the time to listen to this. Episode of the Porn Reboot podcasts. Now whenever you're ready brothers they are three ways that I can help you and your oh compulsive behavior with porn sex or masturbation the first is you haven't grabbed free copy of my book. Please do so it's the roadmap up to ending your behavior porn and masturbation addiction. There is a.
"relapse" Discussed on The Porn Reboot Podcast
"Control over your or sex addiction. I'm your host. JK UK Maisey Certified Sex and porn addiction recovery coach. Welcome to the episode. Now one of the reasons of that you listen to this podcast cast is because you want to stop relapsing well to stop relapse they it's very important to understand how relapses occur. And no it's not as simple as you know I. I felt an overwhelming urge and suddenly relapsed elapsed. Now when I work with clients one on one I use it's who called relapse. Prevention amplifier to help them identify the twelve phases of relapse. However today we don't need to get into twelve phases I'll just be sharing and introductory part into the three basic stages of relapse? It's actionable practical information which you can take advantage job right now as with most of the contents of this podcast. So let's jump right into the first stage. The first stage is emotional relapse ops now brothers during the stage you have literally zero desire to view Offi your last slip. It wasn't into long ago. And the memory of your pay is quite recent so logically it doesn't make any sense to view pornography at this point points. However your emotions inhabits? They don't care about illogical decision because your emotions inhabits are are already hardwired into your brain now moving forward they are for signs of emotional relapse the versus when you find yourself. Isolating yourself shelf right so when you find yourself wanting to be alot stay away from your wife and kids stay in the office a little bit longer. Little do things like that. The next is not staying out -able now if you already going through some sort of recovery program and you realize that you're starting to avoid Loyd your accountability partners not keep in touch with them if you're in some sort of online Grupo Forum or somebody that you communicating communicating with a maybe some sort of sponsor or mentor or coach sort of therapists. And find that you just not letting them know what's what's happening in your life. That is a sign of emotional relapse. The next is lack of self care. So you're not getting enough sleep. You Begin to slack on your your Diet. You're no longer excising. For whatever reason that's a sign of emotional relapse and finally when you're no longer stain. An educated on the reboot process. Now again I wanNA make it clear that this is part of to call the relapse. Prevention Amplifier Apple. Fire within the porn reboot system and within our system during your reboot. It's very to understand what what's happening with you. So education about your reboots missile continuous process as you go through the system and one of the things. You've noticed that men who are going through any emotional emotional relapsed near no longer ensued with their reboots. They are not studying. They're not learning more about the triggered. Did Not trying to understand their biochemistry anymore. For one reason on the other you're done with understanding it you just don't want to be a part of of rebooting. You don't want who identify if I as an addict or with recovery that is a sign and the biggest problem with emotional relapse that you become so reliant on your quote unquote strong logical decisions quits that you deny the fact that you still need to take care of yourself. You still need to stay vigilant. You still need to set boundaries not isolate than to stay out. -able seen logic cannot do any of these things for you eventually. Truly a lack of self care catches up with you and you start feeli. Rationally agitated about your life next thing you know you've arrived the next stage of relapse which is known asked mental relapse and that's the second stage now during a mental relapse. Now you know quite clearly that you wanNA watch dog raphy. But you're logical decision tells you that you should geological logical part of your brain and this is. Where are your willpower exit? Does this constant battle for surpremacy which ensues between the logical decision you made and your emotions and your emotions always way for two simple reasons. The first is that any logical decision that you make depends is on will power and emotions are made up of neuro chemicals so your willpower is eventually going to exhaust you. especially if you've been isolating yourself especially if you've not been staying accountable and especially if you've not been applying self care to your life because these are the things eggs which support your will power said before willpower is finite and your brain can just keep releasing these neuro zero chemicals over and over again and a police that will speak a little bit about biochemistry right now. The second reason why your emotions always win over logic can willpower is because continuously using your willpower at fighting his battle distracts you from other important aspects of your life. Sure you might be a highly successful individual an individual who has developed his willpower to a very high level. But unless you're a mall core a reclusive some sort with no responsibilities. You're eventually going to seek a brief excape and take a break from the battle in Auburn to focus on and other responsibilities right. You've got kids you've got a family you've got a business to run. There's so many things which are happening on your life. Are you able suit on a daily basis you know week after week focus on staving off a mental relapse that is very challenging. Understand that you are under siege and anyone. WHO's under siege any any fortress? That's undeserved has supplies. But those lies are not gonNa last forever and you'll under siege multiple times a year. That doesn't make sense. Once a year is cool right mentioned being this kingdom. That's under siege. Like you know seventy times a year. It's GonNa fall right so therefore signs of mental relapse the versus when you start minimizing begged impact of past relapse. This very clear side. You know it's not that bad. It wasn't that big a deal. You know it's I got back on a horse real quick minimizing the next is bargaining which yourself and brothers. You guys know exactly what I'm talking about right but you start telling you sell component is the you've been doing so well only once this month. Okay you know what we're GONNA do man which is going to do this once a month and that's it. That is twelve delved times this year. That's not an addiction right. You bargain with.
"relapse" Discussed on KMOX News Radio 1120
"Here and say I'm don't even think about it because I do like some like that you know just stop thinking about it's like going on a diet you don't stop thinking about KQ does you know what I mean but it is pops my mind at least twice a day like when I wake up when I go to sleep because that's when you want to get high as soon as you wake up for you to sleep you know but I just like think of pros and cons like and I think about my brother like I know he's watching me so I would I would feel so much guilt if I went out and got high you know and I have said everything I do is for my brother and that still applies so if I go choose to get high hi from my brother and that's not okay and so what can you tell a kid trying to fill a void maybe they go on an airline thinking about it my friends are doing it how can you stop them from trying it what can you say to them the sources reach out to someone if you get a feeling thank you for it with anything like if you feel like you want to die if you feel like you want to try a certain Dr tell someone because I promise if you tell the right person like a positive person then they're not just going to sit back and be like go do it did they're going to be like okay why do you feel that way you got to talk to people because there's reasons you feel like doing stuff like that so definitely like but we did and we have before we left we had to make like a relapse prevention and I think this would be good for people before they even start using drugs like if they feel like they need to write a list of positive people and write a list of negative people.
"relapse" Discussed on The Porn Reboot Podcast
"Have you ever found yourself worrying about finally finally gaining control of your behavior with porn and masturbation only to relapse within a year or have you given yourself excuse that had you know what has no points in trying to reboot because i'm probably gonna relapse anyway well over the past few years. I've had a handful of clients. It's who relapsed within the first year of rebooting and this was actually after gaining control of the urges gaining control title of the obsessive sexual thoughts and overcoming their fear of slipping and yes. I have clients relapsed. I am the best that what i do but i'm no magician. You are the best expert on yourself. My job is simply to guide you toward self mastery awesome awesome man get on coaching calls with man they ask jay. What's the guarantee that i'll never watch porn again and and my response is the only guarantee is that you stick to the system and you don't do any of the five things i'm about to share with you. That's the only way you're guaranteed recovery so let's get into it the five reasons why men in relapse in their first year of rebooting the first reason is you experience a very strong desire hire to put it behind you basically you don't wanna spend two years or even a couple of months building up new habits changing in your lifestyle and rewiring your brain you just wanna get it over with and have a normal life. Never mind the fact that your addiction lasted years..
"relapse" Discussed on The Porn Reboot Podcast
"Filters. I'll talk to see if it works on not all of those assigns of mental relapse and at this stage it is only a matter of being in a high ariss situation that can push you over the edge so a particularly stressful day going on vacation argument which a wife an explicit lissette scene in a movie something explicit on social media. That's all it takes to take you to the next stage. Which is the physical relapse laps now. This is the one that most of us familiar with and what we usually refer to when we talk about relapse you've relapsed but here's the interesting thing about relapsing thing in watching porn or masturbating now during a slip right many men focus on how much porn or <unk> own how many times that they masturbated during that specific slip and this takes away from the impact of the moment that you actually crossed boundary so the first time you edged means touched yourself without getting to orgasm that first time you in the shower or in bed that first points in you watched for a few seconds and turned it off now. That was the moment that changed everything. That was the catalyst for your mental relapse so your thoughts were not obsessive until you decided to take a specific action such as looking at something explicit or edging and the biggest mistake bake your logical mind makes while trying to prevent a relapse thinking that preventing a relapse is as simple as just saying no right before you're about to masturbate masturbate or ejaculate awards point. That's the big mistake. That's the fallacy. You'll logical mind. Just tells you like oh. You got to do to stop it at the last moment unfortunately that what is the most difficult time to stop so true relapse prevention involves preventing yourself from ever getting to the point of emotional mental physical relapse and that is where a system comes in now one of the most common statements made by my clients when they first reach out to me is this they'll say j._k. I i never wants to even think about viewing porn ever again. That's my goal and you feel that by thinking about porn. You're not truly rebooting. This is not true thinking about porn masturbating. It's actually a normal part of your boot. You can't erase the memories of pornography biography but with the right tools and systems you can control these thoughts until your brain rewires so that means you can control this until your brain casted acid appoint that it's rebooted and you no longer crave the experience and that's it brothers so those are the three stages of relapse from the the relapse prevention amplifier tool into porn reboot system. I hope you guys found it helpful all right. That is my message for you today. I really appreciate your taking the time to listen to this and whenever you're ready they are three ways that i can help you end your compulsive behavior would
"relapse" Discussed on The Porn Reboot Podcast
"Do any of these things for you so eventually what happens is that your lack of self care catches up with you. When you start to feel just irrationally agitated wash your life and next thing you know you've arrived the next stage of your relapse. Which is the second stage will relapse now at this point you know oh you wanna watch porn okay but you'll logical decision tells you that you shouldn't and this is where your willpower kicks in. You know it's a constant on battle for supremacy and this ensues between you'll logical decision and your emotions now. We both know that your emotions always wins but here's why wins a winslet's who simple reasons first reason is that logical decisions all depend on willpower to keep that logical decision going you need to considerable amount of willpower and emotions on the other hand. I'm made up of neuro chemicals so your willpower will eventually get exhausted especially if you've been isolating if you've not been staying accountable and if you've not been taking care of yourself secondly continuously using your willpower our fighting this battle distracts you from other aspects of your life so it's not as if willpower does not work okay and in some rare cases willpower can pull you through but unless you're among or euro recluse with absolutely no other responsibilities. Most of us live in real world so while we are battling with this part afa life eventually get exhausted. You eventually wants to seek some sort of escape escape to take a break from this battle in order to focus on your other responsibilities right. You've got issues in your career. You've got things to focus on in business. You've got relationship relationship to maintain. You've got kids. Take care off right now. They are a few signs to be aware of an impending mental relapse and the first one is when you i notice that you've started to minimize the negative impact of your pass relapses like you're not even thinking of how you last relapse affected you the second and if you catch yourself bargaining which yourself so let's say you find yourself saying things like you know what else teaches once a month right. That's that's not bad once a month or when you say just this one time this is the only time because it's an unusually strong urge you bargain with yourself by saying you know what only masturbation no part art. That's what it is right when you catch yourself doing that that is a sign of a mental relapse. The third is when you experience increase surges for no reason boom the on another level and finally when you find yourself searching for ways to slip so you start looking at triggering material on social media looking at sexually stimulating images you know getting on twitter or snapchat or you find yourself quote unquote testing your phones filters..
"relapse" Discussed on The Porn Reboot Podcast
"Now one of the reasons why you listened to porn reboot podcast is probably early because you want to stop control your relapsing well to stop relapsing. It's first important to understand how relapses occur and no it's not as simple as oh. I felt an overwhelming urge and suddenly relapsed. I gave into its now when i work with clients one on one i use a it's who called the relapse prevention amplifier to help you identify the twelve different phases of a relapse but we're not going to be getting that indepth into its today today. I'll just be sharing the introductory part of that too which are the three basic stages of relapse and it's actionable actionable information as always which you can take advantage off right now so let's hop into the first stage. The first stage of your relapse to pornography vienne masturbation is what i call emotional relapse and during this stage you have zero desire to view pornography right so your last slip usually really wasn't too long ago so the memory of the pain is really recent and logically it does not make sense view inaugural however your promotions and habits they don't care about illogical decision because these things are hardwired into your brain so they are a few signs to look <unk> out for for an emotional relapse and i when you start isolating yourself right you start moving away from your loved ones and spending quite a bit of time on your own and secondly is not staying accountable. You drop accountability for whatever reason the third is lack of self care in not getting enough sleep. Your diet is slipping. You're not exercising and finally is not staying educated on rebooting so you feel that you know everything. You need to know about this process so you don't studied anymore anymore. You're just like you know what i'm in control. I don't need to listen to the podcast anymore. I don't need to be part of the group at o. Needs to read any more books now the biggest problem with emotional relapses assist that you've become so reliant on your quote unquote strong logical decision to quit that you denied a fact that you still need to take care sheriff your stuff. You still need to stay vigilant. You still need to set boundaries. You still need to stop isolating and you still need to stay accountable so logic khandu..
"relapse" Discussed on The Q&A with Jeff Goldsmith
"And then when ninety percent of the people relapse, it it just kind of ballooned and so everybody from the midwest and east coast were sending their kids down here. They would they'd go to these treatment centers that were just profiting off them, and they would relapse and the cycle would just keep going back and forth and into now known as the relapse capitals. They pointed on the film, and it was the perfect place to. Tell the story with I think, you know, to do people understand it more than anyone one of the things the documentary really gets into well is the kind of follow the money concept of the business of you know, relapse centers. Sorry, the rehab centers that turned into relapse, and you know, having urine tests for three to five thousand dollars protests, sometimes people being tested three times a week. You you could see the cycle of the referrals and wanting more clients and just the insurance companies being built until there's nothing left really for the client. Who's probably dropped the first chance that they can be dropped by the insurance company. So for the follow the money aspect one thing I was curious to the documentary didn't get into as much was how does funding work for Allie and Frank because they they were taking it on as a fulltime job. They definitely are altruistic and taking it personal because they are former addicts themselves, but are do they? Seve or does the foundation received some sort of a payment when they turn a client over to one of the centers that they have determined is actually in the client's interest in is not like a sham. It's a good question. I mean into little confusing convoluted, but Allie is by definition, a marketer. And so she's employed by daylight detox, very reputable, great organization, and so she gets paid a fee a flat fee to market. Now. The issue for patient brokering is when you start to get paid per person hurt when we get paid per person. And so those laws really start to shape and take place about four or five years ago. Three or four years ago. Frankie the same thing. Franken his mom have an organization called the fucking on organization foundation, and they work with people and they become marketers for them. But not by individual people because that'd be patient brokering in in in some ways, they kind of do the same thing. But and I think Ellie says it, you know, the best way is like, you know, her first question, isn't, you know, what kind of insurance? Do you have? It's, you know, do you need help you want help, you know, are you in a safe place? I mean, we were down yet in our UNICEF place. And when we were down there, I was approached on the street and asking if I if I needed treatment, and if you know, if if I needed a place to go, they would help me out what kind of insurance did I have. And you know, maybe they thought they had good insurance. So I mean, it it's it's it's out there. I mean, it's it's ugly. When you guys sit out to make your documentary, just talking logistics. You had the. Time of the weekend that you're gonna follow them around the seventy two hours what kind of equipment what kind of crew. Did you go down there with what how many cameras reusing we had about? I think in eight person crew to camera guys the DP, Michael Goodman, and then the camera. Greg Taylor, we had to a seven SS that we did all the car mount stuff with or if we had to go like really light footprint into, you know, film this guy shooting heroin over here or something, and then we had Sony fifty five's. And then when we shot the interviews we shut that on the Alexa Mira. Okay..
"relapse" Discussed on Gettin' Grown
"And don't trust anybody out there. That tells you arrived like don't don't I'm wary of women that try to describe their processes finite. It's done. I've reached the summit and I am perfect. I am on this journey, but I busted my s to get to this place. So I'm not I'm not interested in going back. Now, it's not going to serve me. It's not going to serve. My child is not going to serve the community. I'm not here for that. I am modeling what it looks like to feel the fear and do it any way to move through one step at a time. And I will say that black and white thinking of I mess up today. So it was all over that is very characteristic and typical of perfectionists and overachievers and women that are customer excellence. Feel like I'm either excellent Oruma failure. And I feel that it is safest and most productive forest to say I have made a mistake. But I am not a mistake. And so I can move through this together. I can move through. It's just like if if you said you were on a diet this dis make me a little nervous. But if you say, you're on a diet, and you've been eating, you know, whatever the fuck people on diets eat, I don't know. Like salad and cucumbers and shit. And then you eat a slice of cake. The inner critic want you to say because you ate the size of cake. You will never lose weight again, and you might as well, just groaning trash, but. That weight release that you are calling for is going to rely on you not getting stuck in that one mistake, you made giving yourself permission and make that mistake and go back to doing what you knew was. Right. And it's the same thing with choosing your thoughts. You are going to revert and relapse that is inevitable. It is guaranteed because you've gotten so used to thinking these thoughts, but is on you to say, you know, what I had a relapse. But I'm not staying there. I'm choosing to move forward. And do something better choosing give myself that same compassion that give my best friend of she fucked up. Right. It's it's on us to give that same compassion that we are so used to giving to everybody else. Word always say here. I know. If you hear somebody talking about me like I talk about me. So green. She better give me see you getting me together. Honestly, you're truly getting together this real. Yeah. It's not it's not a one and done thing. This is something that I do every. And that's why I say being a free spirit requires great discipline. Don't get to this point of freedom, and self expression and self possession without putting structures in place..
"relapse" Discussed on NEJM This Week - Audio Summaries
"The investigators performed a comprehensive analysis of samples from patients who had a relapse of acute myeloid leukemia AM L after he a poetic stem cell transplantation to define the genetic. And epi genetic alterations that allow leukemia cells to escape the graft versus leukemia effect and to determine whether the dysregulation of known immune related genes is a common feature of relapse after transplantation on Exon sequencing the spectrum of gained and lost mutations. Observed with relapse after transplantation was similar to the spectrum observed with relapse after chemotherapy, specifically relapse after transplantation was not associated with the acquisition of previously unknown AML specific mutations or structural variations in immune related, gene. Enes. In contrast, RNA sequencing of samples obtained at relapse after transplantation reveal dysregulation of pathways involved in adaptive and innate, immunity, including down regulation of major histocompatibility complex m h c class to genes to levels that were three to twelve times lower than the level seen impaired samples obtained at presentation flow Saitama tree and immuno history. Chemical analysis confirmed decreased expression of m h c class to at relapse in seventeen of thirty four patients who had relapsed after transplantation evidence suggested that interferon gamma treatment could rapidly reverse this pheno type enamel blasts in vitro. Overall survival with value MAB after chemo radiotherapy in stage..
"relapse" Discussed on The Virtual Couch
"Riling lists stock here. Where's the inlets guards a little bit now? Yes, that definitely all unfolds in the room. I think exactly end I really work with the clients on what do you want like, you know, I asked myself that sometimes with through I want. And so it's just a goal oriented approach posits a positive approach to what's going to be happening next for for for a client in for therapeutic relationship for trust for ninety percent of people relax according to the third fence. Like I think it's part of the work. I don't. I, you know, I tied she, it's. Don't get. Find it. I'm not like I'm not, you know, finding a relapse. I'm just assuming that for some of my client majority of the clients as chance that a relapse could happen. So we talk about it beforehand. I can liken see a client Bank pre laps. I said, you know, it's looks like you're in relapse even though they haven't had a drink or you end up on the behavior yet. I can feel it. I'm sure they can feel it to about it before it happens and yet exactly the one. I like I like how you're just grateful that you put out. This statistic is I do even I'm noticing in my own brain that struggle of winnow client is saying. If I don't wanna ever relapse again, not wanting to kinda just say, hey, look, you're probably gonna, you know, but I know we go with that struggle of where we don't wanna be handing them this license, right? But then also wanting them to know that I love what you said. That's just I'm still here. That's part of the process. I'm gonna. We're gonna work with it sometimes all say they'll say, I'm sure you're disappointed. And I say, no, I'm glad that we can work on this together. Right? Yeah. Yeah. I like lake, Rebecca. When you're saying I haven't really thought of that the the like they are relaxing yet. They're not because you're right. I, we noticed and I feel like when we were talking earlier about it's hard to get people to do the work when the waters are calm that. Right. So when you start to see him say, I think I'm good. You know, I don't think I need the mindfulness practice every day, or, you know, I've been too busy to exercise or whatever it is that kind of what you're talking about. You start to see. I should have been a lot of ways. I'm sure you've heard this, but they say that relapse his process, not in a vent, right? Eleven laps. It's the process of relapse. I'm so I think yet shows up in a lot ways. It shows up in not going to meetings or not connecting with other super people or or not exercising, not meditating, whatever it is for them on. And then you noticed these little choices choices points, right? Where it used to be. We come to crossroads when we're really committed to recovery, it's the recovery choice like, okay, I'm gonna decide to call my sponsor, decide if that event because I feel a little weird and deadly. It's I talked to my ex-boyfriend we use, but I don't think he's using anywhere. You know, we just your gut goes, you know. Maybe that's a good way to jump into this really quick right out of the beginning. You start out talking about the noise in your head and I loved it. We normalized that a lot of people feel like that's unique to them or all the feelings that accompany recovery, and then I would want to know. I'm really curious when you Claburn on a book who who's quotes is just like a garden that needs to have sunshine food and water on a regular basis, you recovery will need to grow a will grow and thrive. When you begin to nourish it with a steady supply of mindfulness, whose quote..
"relapse" Discussed on KBNP AM 1410
"Is no resistance and you can't get them to admit it outright but they're basically saying there is resistance with out saying there is resistance and part of the reason for resistance is people not applying the products every month flight they're supposed to so it's like antibiotics yeah a lot of people they get sick they go to the doctor they get antibiotics they take the antibiotics until they feel better don't finish the course and then sometimes they get a relapse and get worse than what they were sometimes they do get better but that's how we get back to real resistance that's what how the developed is people not taking the antibiotics and finishing a course of antibiotics like they should see you end up with bugs when it comes he antibiotics bacteria that are resistant and can multiply and spread that resistance in that's also how it works with fleeing tick products as while boat with antibiotics the actually sage sometimes because i was recently antibiotics and on basically they said that i had a yogurt because he antibiotics from not only killed a bad bacteria but will also kill the good the bad dietary two and and rocard is a replenishment can you give your pets if they're on an antibiotic will they can you give your letter absolutely you can yep okay and i have certain brands that i recommend so a in cases like that but also if i knew a pet is prone to gia upset from any antibiotic you know i'll put him on probiotics than i have some patients that are on probiotics all the.
"relapse" Discussed on Monocle 24: Meet the Writers
"So he came in at each when he was quite young and then had many many trips in and out of various we have so many relapses and he then eventually ended up in this one me have where he had a full recovery if he can call it that and way he met either his wife to be and at that point they were very happy you know they've they were happy they got engaged as married she was a american she was american though born in hong kong as she had grown up in london meeting they had four children they were very active in the in the world the recovery they were very active philanthropic lay we saw each other loft they had wonderful life until one new year where they had a a glass of champagne as as people do yeah and us recovering addicts no not to do 'em what happened then and that was really the beginning of the relapse and i do mean by that that they meet this started taking also drugs because i think a relapse is his state of mind this much as anything else and he was very gradual process but they eventually will take him may serious amounts of drugs and we were increasingly worried about them at times frantic about them trying to plead with them trying to intervene you knew this concept of interventions we good together as a family and speak today addict to try and in a bring about change we had normally.