35 Burst results for "Poss"

Most American men reach Wimbledon's 3rd round since 1995

AP News Radio

00:34 sec | 2 d ago

Most American men reach Wimbledon's 3rd round since 1995

"Ego shrink has continued her victory streak to reach the third round at Wimbledon The top ranked tech has won 37 consecutive matches The longest run since Martina Hingis also won 37 straight in 1997 Other winners on the women's side Thursday included fourth seed Paula badosa along with Petra kvitova Jesse pagola coco Goff and Simona Halep but 6 seed Karolina Pliskova was beaten by Katie boulter Men's second seed Rafael Nadal won his match in four sets Joining stephanos sisi poss and Taylor Fritz in the third round Number 12 Diego Schwartzman lost to Liam Brody in 5 sets I'm Dave

Paula Badosa Petra Kvitova Martina Hingis Jesse Pagola Coco Goff Simona Halep Karolina Pliskova Katie Boulter Tech Stephanos Sisi Poss Rafael Nadal Taylor Fritz Diego Schwartzman Liam Brody Dave
Vaccine passport protests in Europe draw thousands of people

AP News Radio

00:54 sec | 5 months ago

Vaccine passport protests in Europe draw thousands of people

"Thousands thousands thousands thousands of of of of people people people people have have have have gathered gathered gathered gathered in in in in European European European European capitals capitals capitals capitals to to to to protest protest protest protest recent recent recent recent coronavirus coronavirus coronavirus coronavirus restrictions restrictions restrictions restrictions including including including including faxing faxing faxing faxing possible possible possible possible sometimes sometimes sometimes sometimes by by by by some some some some governments governments governments governments throughout throughout throughout throughout the the the the consonants consonants consonants consonants demonstrations demonstrations demonstrations demonstrations took took took took place place place place in in in in Athens Athens Athens Athens Helsinki Helsinki Helsinki Helsinki London London London London Paris Paris Paris Paris and and and and stock stock stock stock home home home home marches marches marches marches in in in in Paris Paris Paris Paris to to to to hundreds hundreds hundreds hundreds of of of of demonstrators demonstrators demonstrators demonstrators protesting protesting protesting protesting the the the the introduction introduction introduction introduction of of of of a a a a new new new new cabinet cabinet cabinet cabinet nineteen nineteen nineteen nineteen poss poss poss poss in in in in Sweden Sweden Sweden Sweden where where where where proof proof proof proof of of of of vaccination vaccination vaccination vaccination is is is is needed needed needed needed to to to to attend attend attend attend such such such such events events events events some some some some three three three three thousand thousand thousand thousand demonstrators demonstrators demonstrators demonstrators marched marched marched marched through through through through central central central central stock stock stock stock home home home home in in in in London London London London protesters protesters protesters protesters chanted chanted chanted chanted freedom freedom freedom freedom as as as as they they they they marched marched marched marched against against against against regulations regulations regulations regulations requiring requiring requiring requiring mandatory mandatory mandatory mandatory Cabot Cabot Cabot Cabot nineteen nineteen nineteen nineteen Bucks Bucks Bucks Bucks a a a a nation nation nation nation for for for for British British British British medical medical medical medical workers workers workers workers Dr Dr Dr Dr medic medic medic medic Ricky Ricky Ricky Ricky Allen Allen Allen Allen says says says says the the the the British British British British government government government government is is is is putting putting putting putting its its its its people people people people but but but but I I I I picked picked picked picked the the the the wrong wrong wrong wrong people people people people the the the the N. N. N. N. I. I. I. I. K. K. K. K. the the the the police police police police picked picked picked picked a a a a fight fight fight fight it it it it cannot cannot cannot cannot wait wait wait wait this this this this is is is is the the the the end end end end of of of of the the the the vaccine vaccine vaccine vaccine is is is is going going going going to to to to implode implode implode implode now now now now the the the the medical medical medical medical stop stop stop stop they they they won't won't won't have have have it it it Karen Karen Karen Thomas Thomas Thomas London London London

Paris Helsinki London Athens Sweden Cabinet Cabinet Cabinet Cabine Cabot Cabot Bucks Bucks Bucks Bucks Dr Dr Dr Dr Medic Ricky Ricky Ricky Ricky Allen British British British Britis N. N. N. N. I. I. I. I. K. K. Medical Medical Medical Medica Karen Karen Karen Thomas Thoma
France's Macron sparks outrage as he vows to annoy the unvaccinated - CNBC

AP News Radio

00:53 sec | 6 months ago

France's Macron sparks outrage as he vows to annoy the unvaccinated - CNBC

"French French president president Emmanuel Emmanuel mackerel mackerel has has provoked provoked outcries outcries in in parliament parliament and and protests protests from from election election rivals rivals by by using using a a vulgarity vulgarity to to describe describe his his strategy strategy for for pressuring pressuring vaccine vaccine refusals refusals in in an an interview interview published published by by French French newspaper newspaper le le parisien parisien McCall McCall used used a a French French word word meaning meaning to to rile rile or or to to bug bug when when referring referring to to France's France's unvaccinated unvaccinated people people I I think think we we will will continue continue to to rile rile to to the the end end the the president president made made the the explosive explosive from from mark mark as as lawmakers lawmakers all all heatedly heatedly debating debating new new measures measures that that would would allow allow only only the the vaccinated vaccinated to to enjoy enjoy leisure leisure activities activities such such as as eating eating out out his his use use of of the the language language more more commonly commonly heard heard at at the the countess countess of of French French cafes cafes further further complicates complicates the the already already difficult difficult passage passage in in parliament parliament of of the the government's government's planned planned new new vaccine vaccine poss poss I'm I'm Charles Charles de de Ledesma Ledesma French French president president Emmanuel Emmanuel mackerel mackerel has has provoked provoked outcries outcries in in parliament parliament and and protests protests from from election election rivals rivals by by using using a a vulgarity vulgarity to to describe describe his his strategy strategy for for pressuring pressuring vaccine vaccine refusals refusals in in

Parliament Parliament Emmanuel Emmanuel Mackerel Mac Le Le Parisien Mccall Mccall Mark Mark France Charles Charles De De Ledesma Government
"poss" Discussed on OnEducation

OnEducation

08:44 min | 10 months ago

"poss" Discussed on OnEducation

"I watched all the batmans of watched all of the marvel movies multiple times You know i like you know. I'm florida Like like i like. I like good fiction. You know movies and content. I've never gotten into spider man. I have to be forced to watch by man. i just. It's just one of those things that have never been to tell me how i am just a i'm just a classic straight up. Spider-man fan i i love spiderman. I've always spiderman as a character. I think that the story of peter parker this common kid. Who's common nerdy kid who manages get superpowers. I think just speaks to a lot of people for a lot of different reasons but the tom holland stuff has been good the newest spiderman now that he's in the ncaa has been great. And what is the teaser for. This makes it clear that so many awesome. Things are going to happen in this movie. that we we're getting a full on multidimensional spiderman movie with they're going to be pulling tobey. Maguire villains david and yet the villains and the other spider men are both in this movie and it looks like we might even be getting like a multi sinister six which is awesome and amazing. And i cannot even tell you. I've watched this trailer like seventeen times at this point and it's caused my wife and my son and i to start a straight rewatch of all like eight movies. That would lead up. So we're going all the way back to two thousand two tobey maguire where we're watching the two thousand two tobey maguire spiderman than we We're almost at the first one. And then we got second and third. Then we'll do the to andrew garfield i'm also making my son watch the Ninety seven the late ninety s Spiderman cartoon that was awesome on fox kids back in the day so it's all spiderman in my house right now. Getting ready i might have. You might have been able to get me if they had done what i thought they were gonna do at one point which was cast. Donald glover as miles morales But they didn't. Yeah so they didn't want me so he's actually. I was kinda here for that. So it actually. He is he's miles morales. Says uncle technically oh is he in the is ian novas his appearance the way they the way they credited him in his appearance in the The the first spiderman tom holland it implies pretty heavily that he would be milder analysis. Uncle but interesting there we go so maybe there is a maybe. Maybe we'll see childish. Gambino we make we make you never mp down. I might be down for that I it's it's funny so i've been thinking about this a little bit kinda. It's it's funny that the last episode we talked about this streamer who is Who was simulating his his stream as if he was a sim character in letting people And you know. I've been going through some meanings at work vetting basically online community platforms You know for for use at at at paper. Add one of the things that is striking me as as obvious these days is the gaming in game affiliation You know has has has so become universal in its adoption and usage and is is a common passion of so many people And that's what. I've been thinking about this week when i've been in these meetings but also What's really funny is You know paper uses slack and Someone had had started a video games slack channel in our in our slack companies slack and then wrote in the general slack. Know if you're down with video games join join the video games channel and it was instantly full like we have about two hundred full time employees at paper and there was there was instantly like fifty people up in their having great conversations of video games and it was so funny and revealing It shouldn't surprise anyone that a technology company there would be people in video games obviously but It just you know between these meetings and that that that funny slack experience just reminded me how important it is that that that teachers like. I can pivot this education super easy unless the educators need to remember that like like game of the -cation has become universal in its application and it is. It is a language that almost every single human understands in some way shape or form. And if that's not what we're trying to do in education that i don't know what the hell we're trying to do because what we actually need to be trying to do right is is finding those universal ways that we can all connect with each other and learn together and it's becoming so obvious they gamification is one of those ways. Yeah at They're still hold outs right. Like there's still people. And i think that i. I know we've talked about this. But i i to me. It's that it's that miss of like the misconception by so small number of people who don't understand like games can be a wider conversation than just saying like. Oh it's a bunch of middle schoolers on fortnight cursing at each other in being derogatory to women like that but also like that. That happens every other job like that. It just happens at work like if you ever worked in a restaurant. Yeah that happens there to like. Have you ever been in to watch a football game at a bar happens there to like say that that happens and therefore means all of those things are bad. I don't agree with ray end. So yes there are parts of it that people can point to and have problems with gaming in general hundred percent. Don't get me wrong. Twitch just went dark this week because of problems in that community in that space hundred percent understand. Yeah but that doesn't mean that it's all bad right. And i think that when we talk about games as a universal language going beyond just video games in general is also a really powerful thing because the the the the psychology of why games work as a learning tool is true beyond just video games. It's just in my opinion. Modern kids these days are more interested in video games because they're more dynamic engaging than playing a game of scrabble. Not that i don't like scrabble. Scrabble is fine. But like you know. There's a difference between video games and board games and card games but the psychology. The game mechanics the things. We can integrate into classrooms and used to teach are still there but also that community piece. I mean i. I know you support this but just having a board game night with your family or friends. That's the best right like just hanging out chatting laughing making fun of each other for bad decisions. Those are all true across the board. And they they do 'cause communication 'cause interaction 'cause human connections and so two to get sidetracked and stuck on the little pieces. That are not that i you know. I don't support and i think we absolutely need more inclusion of it and acceptance of it in the education space and we're getting there we've moved that needle wave farther than we have in a long time for sure for sure so just something to think about for all you there and you know if you ever have any questions about like gamification you know there are tons of people that are super willing on twitter to talk about this and even guide you through it including myself and i won't be rapper. Probably brad to probably bread. He's got tons of free tons of free time so so there's lots of people that you can reach out to so if you're still on the fence i imagine if you're listening to this podcast you're probably not on the fence our kind of preaching to the choir here but hopefully you can share this with someone you know they might be on the fence is there might be people listening that agree with it but haven't actually taken the steps in their classroom right. I think that's a definite possibility. There you go take those steps. Take those steps. There's the takeaway. Hey we have a really good interview. It's long and and an excellent and so we want to get to it Right away so when we come back we'll be talking to the four authors of inclusive. Learning three six five so stay with.

tom holland tobey maguire morales ian novas peter parker Donald glover andrew garfield tobey Maguire Gambino ncaa florida fox david ray football brad twitter
"poss" Discussed on InnovaBuzz

InnovaBuzz

04:48 min | 10 months ago

"poss" Discussed on InnovaBuzz

"My business takes a lot of that crash off as well absolutely. And i think that one of the things that i really love about. How businesses are represented now more. So is that a lot of ceo's business owners are talking about the teams they with or the support that they have in order to run their business as well as they do I know that you have a team that you work with. I have a team that i work with. And i wouldn't be able to do nearly as many as the things if i didn't have that team and talking about that team is really powerful. Because it shows other ceo's and business owners that having support in acknowledging that support is is okay and it's not only. Oh hey it's something to really celebrate when we're able to build a really well rounded secure excited team that's powerful that's a very powerful part of business and it's a skill that takes some time. Yeah yeah that's that's a really good point. The it occurred to me as you. Insane that because One of the things that i often do. And i think you know i'm i'm elevating my team member because i've sent somebody says hi. This has been really fabulous. And i will say well. That was my team member. I didn't do any of that up at this team member. That's really great at that. She does a wonderful job She's put this together. And so i'll pass on your feedback to make sure that she knows that you know this. This was really appreciated and in some ways. That's almost a little devaluing on on self again. Isn't it because we kind of deflect prize and yes that's correct person that that really did. What my compensation partner is giving me gripe feedback on but as you say. It's i was the one that trying them. I was the one that growth into the company and hide them. I'm the one that notice. The might sure they happy. And i haven't environment that that can achieve what they're achieving. Absolutely and i think that that's really common and it's more common than even even that example so one really common example. When says oh you have a beautiful blue sweater on today. And it's so to say. Oh while they were selling them at target or i got this editors door or my friend gave it to me instead of just saying thank you. You know that happiness just seeing thank you is almost foreign to us and when we are able to just say thank you. There's a sense of wellbeing. That really comes through us that we don't feel when we you know. Move the praise way. Like you're talking about and so i would invite the listeners. The next time that you receive a compliment try not to explain it away in any way any compliment but just say thank you and if it is information. That's really supportive of the team that you have share that information with your team and invite your team to able to say thank you to think that signals going to add that second pop but you did it for me so thanks. I think there's the two things so thank you behalf of the team and received the feedback on. I like dining blinded away and then haas poss on that feedback so if my sweater my friend had gifted me the sweater and you said hey that looks great on you. I can say well thank you. That's very kind of you decide that..

haas poss
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

02:12 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"Less <Silence> <Speech_Male> <SpeakerChange> <Speech_Telephony_Male> tied <Speech_Male> to <Silence> ames <Speech_Male> and <Silence> hypotheses <Speech_Male> by maybe <Speech_Male> based <SpeakerChange> on their <Speech_Male> record <Speech_Male> and based <Silence> on <Speech_Male> the <Speech_Male> systems. <SpeakerChange> They <Speech_Male> use the excitement <Speech_Male> of the of the top <Silence> just ability <Speech_Male> to <Speech_Male> find new ways <Speech_Male> to explore <Speech_Male> biology. <Speech_Male> The find <Speech_Male> new questions <Speech_Male> or <Speech_Male> the <Speech_Male> field in in your <Silence> come. <Speech_Male> <SpeakerChange> I think you're <Speech_Male> in good company. They're <Speech_Male> one of the favourite <Speech_Male> sentiments <Speech_Male> of <Speech_Male> previous <Speech_Male> guests. We had was hans clever. <Speech_Male> Who said very <Speech_Male> similar thing <Speech_Male> is that everyone <Speech_Male> always focused <Speech_Male> on hypothesis <Speech_Male> driven science. Sometimes <Speech_Male> you just gotta look <Speech_Male> at thing and try and <Speech_Male> figure it out. And <Speech_Male> i <Speech_Male> i really <Speech_Male> i appreciate <Speech_Male> that. 'cause i always feel <Speech_Male> so guilty when <Speech_Male> i'm talking to my trainees <Speech_Male> and you know <Speech_Male> there's this overarching <Speech_Male> question. Is <Speech_Male> this just a scripted visit. <Speech_Male> Where's the <SpeakerChange> <Speech_Male> Mechanism <Speech_Male> you know. It's nice <Speech_Male> to hear a <Speech_Male> season in <Speech_Male> in you know <Speech_Male> high achieving <Speech_Male> <Speech_Male> scientists like yourself <Speech_Male> getting back to square <Speech_Male> one for all of <Speech_Male> us really which is <Speech_Male> just like look at the thing. <Speech_Male> Isn't that cool. <Speech_Male> Let's figure it out. So <Speech_Male> i love that <Silence> extra sharing <Speech_Male> and thanks <SpeakerChange> for <Speech_Male> all your sentiments <Speech_Male> insights <Speech_Male> in this interview. This <Speech_Male> has been a really fun <Speech_Male> chat for us. <Speech_Male> We're gotta <Speech_Male> come down duke <Speech_Male> in and catch a game. <Speech_Male> My man <Speech_Male> Put us on on <Speech_Male> the on the business english <Speech_Male> please. <SpeakerChange> <Speech_Male> Yeah <Speech_Male> i don't know what kind <Speech_Male> of pull i have there. But <Speech_Male> <Speech_Male> <Speech_Male> i'll try if you want <Speech_Male> me to. <Speech_Male> Well we'd be happy <Speech_Male> just to visit the lab <Speech_Male> can <Speech_Telephony_Male> but again <Speech_Telephony_Male> we. We really <Speech_Male> genuinely appreciate <Speech_Male> your time here <Speech_Male> and sharing <SpeakerChange> <Speech_Male> with our listeners. <Silence> Thanks again <Speech_Male> <Speech_Male> thank. You really <Speech_Male> appreciate that. <Silence> <Silence> Thank you <SpeakerChange> <Speech_Male> all right. <Speech_Male> Guys that brings us to <Speech_Male> the end of this episode. <Speech_Male> It was a great <Speech_Male> one. The last one before <Speech_Male> number <Speech_Male> two hundred <Speech_Male> tune in for that <Speech_Male>

"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

05:52 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"Compare them understand what's similar and what's different and form collaborations and new networks and so That's that's why we did this. It's really too again at formalize the formalize this community to bring attention to To to recognize the people who are who are making the big findings and who who've had such wonderful service over the years and write something for the training so This this there are. We're finding out you know. There's there's a enormous community interested in how tissues regenerate but We haven't had that that that recognition form of society where we can have targeted events in so that. That's what this is for and will will meet regularly will We're establishing sama award. Some career development mechanisms some webinars. And i am excited that this is happening in real happy to be the first president of the of the society. Yeah everybody can look forward to the. I think the first in person meetings plan for twenty twenty. Three's i right yes. Yeah we're we're at the point. Now of of from of receiving proposals for for sites and for local organizers. So hopefully we'll we'll know more in in a couple of months. I would say where where that would be. Presumably a it will be a distant memory will be in the clear. We can all get back together in person. I hope i won't take that long for us to get a chance to chat with you again dr pause but we're going to close up the formal scientific part of this interview and gets a couple of peripheral questions if that's alright to finish I what is the best piece of advice that you've ever been given either. Professional are not well. I think. I think if we stick to professional i really liked what might graduate advisor told me As a graduate student sutan slab and tighten it was discovered the the basis of antibody diversity Always been really good at finding in answering the big questions..

sama award sutan slab
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

05:24 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"So you know the questions left biology. It becomes so deep in specialized and as i said this careers worth of work in increase. There's not much left. You gotta really go deep. How do you maintain such a diversity of interests focus in the lab and produce like what's the formula. What's your secret can well i. I think it's pretty easy. We studied whatever the the post doc students want to study. And so i. I'm not married to any particular tissue in certainly as my colleague snow not to any signaling factor gene or or or or You know molecule so I think that you know the best way to train has stocks particularly if they want to run their own lab for savalas to support what they want to do and often people want some space and they want to start something new so i support this so they they can essentially generate a program of around that they can take the nc ten years of discoveries from so so it sometimes. It's says easy. As just saying i don't want to decide what we work on. Let's what do you wanna work. Let's talk about it. let's talk about. Who else is doing that. Where where the openings are. And i'm like i was saying before for for heart regeneration this topic that where there's many many many lab studying eh. It's moving into the applied space and there's not as many open questions in the discovery space as you said you have to go deeper by for other tissues. There's there's much. I think there's much more room for spinal cord regeneration zebra fish. There's really only a handful of labs worldwide work on this. I'm amazed by this. Because it's it's one of the more spectacular events in nature when you can fully transcend the a spinal-cord cut right through it. Paralyze animal six weeks later Swimming around like nothing happened and so there needs to be more people working on this. We know very little about it at the basic mechanistic level. And it's that's a great place. Ripe for a for a trade. Come in ask questions and start around pregnant they can. They can take out so you kind of look at I kind of look at it. As a portfolio. The these tissues are a different different levels in the discovery in the applied space and in in the number of labs who are looking at them worldwide. And i think you always wanna have something that are kind of out there that no one else wants to work at them and maybe we try to change that situation by finding something interesting spun cord heart all these different tissue types. You're busy guy dr price. He's got a lot of different things on your plate. You're of course..

Swimming dr price
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

05:42 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"Why don't you tell us why do is a tremendous place for stem cell biology and regenerative in general medicine. And what you're actually hoping to accomplish as the new head of the duke regeneration center. Yeah well it is a place in. Durham is A really great place to live with a booming technology sector in the aloke low cost of living compared to other places. So i've been eighteen. years is really impressive. See what's going on. With with durham and You know the folks coming here just to live here and and to work at great places like like duke like even see chapel hill but that the parts of i always been At duke The faculty here and the students here Yeah they're impressive It's been it's been my privilege to to work here I i would say that May maybe ten years ago We were We we we have A great set of traditional departments biochemistry cell biology pharmacology and cancer biology. But we've we've. We've never had some formal entity that could acknowledge formerly again the the importance of stem cell and regenerative biology. I think We had The people here and developmental biologist People using worms flies and my sincere chickens and fish and mice so Understand petitioned form and how embryos are padding but then we have a great by medical engineering department in school of engineering. Gets on one nice campus and then you mentioned that the the clinical engine but So the goal of regeneration next was just to get get these people together and talking more about the science and Initially science now what what. What are the questions in in regeneration that we should be thinking about. And we framed it as tissue regeneration and not so much stem cells. Though we all up stem cells recognize their their place but we also see regeneration as kind of the ultimate goal and And where we could have a particular angle. Because again i think because the base of a developmental biologist there interested in understanding how tissue forums whether whether or or or not saying the case of regeneration it would involve stem cells or or some.

duke regeneration center Durham chapel hill durham cancer
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

03:37 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"It could be it you know can come her heart regeneration come from it. Many ways there are some incredible groups Working at ways to to create Hundreds of millions billions of cardi myocytes in culture get them more mature improve integration and Improved ability of of those selves to electric lameck mechanically couple and to be to be taken by the recipient. And that's a that's a that's a It's a lot of challenges there but I mean it's it's it's been progressing and it's a great way to go at it. I think versus putting in stem cells and asking them to to do quite a bit And of course. There's been a lot of controversy there. there are reprogramming approaches shooting in shooting in viruses or cocktails of some sort including drugs to try to change the identity of cells that turn them into muscle cells incident exciting idea of turning turning fiberglass blasts into into cardi my site like cells. I'm just a really exciting idea. The big challenges there in efficiency and then we have our again the Like the mouse keys to try to make some population muscle cells divide by By giving them the right signals so they have their big challenges there. Of course you you wanted to give the right signals in the right doses at the right times certainly don't want too much of a response and so all of these have challenges you mention artificial hearts and engineered devices I think everyone is acknowledges excited excited about those those advances. it's possible they'll come together There's exciting idea that if you take the load off the heart and you provide some type of genitive stimulus may be you. Can you can have the best of both worlds and So as you said everyone everyone wants this to happen and I don't see the says competing ideas. I see these as you're taking many different approaches to try to get you try. I mean first of all do of course understand science but also to get Have less people. After transplant list. Less baseball experience occurred failure to really exciting time. For the field and ducas in many ways the at the forefront of a lot of this work the basic science where it can force. Also the translational work like we talked about. It's no secret that we're fans of do here on the show. Of course dalen. And i both went to duke for undergrads and duke. Medical center actually has always been a tremendous powerhouse. And in some ways as you know dr posits kinda tale that wags the dog at duke right. it's a world class medical institutions. So you've been at duke for almost two decades and you've seen its evolution to be like a great place for regenerative medicine particular i through the regeneration next initiative that actually evolved into the duke regeneration center. So you don't necessarily have to convince me. Dale on about why duke is so awesome but for the rest of our stem cell centric audience..

lameck ducas dalen dr posits baseball Medical center duke regeneration center Dale duke
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

03:23 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"Target cells and essentially to try to get them to divide and divide better than than what they do produce muscle that could make a clinically relevant difference after after a heart attack or or either. Are there soon after it or or long. After our are we at the stage of Taking information from what we know about heart regeneration trying to translate it yet. Definitely and i. You know harvey generation versus maybe other types of regeneration like limb regeneration which is a real challenge harvard generation. I think i think. I think we are there. And i think that while there's a lot to find in zebra fish still discovery biology. How did they do it. And why do they do it. And especially when you get down to the level of gene expression. Thousands of genes changing to enact regeneration programmes levels. Going up and down and house at all orchestrated. I mean there's a ton of stuff to do but do do we know enough now to try hard to trigger heart regeneration of mammals and i i would say yes so. It's an interesting time where you have a discovery really active discovery community but but even the in a really hardcore basic scientist like myself agree. That i think i think we know to to be to be banging away in an informed way to to try to improve heart regeneration and so know. I think it's an interesting time but the field where you have the basic scientists vulnerable. Just we have engineers you have more a clinic clinically oriented people coming in and and using the science in Informed way to to try to change things. And i don't know. I think i think in ten years You know we we can see Something happening from that. This that now we will. We will probably see Real real changes implemented you know Improve tissue repair based on the whole of this field. God knows we need it. Heart regeneration huge unmet need. We've talked about on the million times. Everybody knows it by now. It's been one of the top. Three clinical targets for cell based either dodge insists are stem cell all cell based regenerate medicine. It's it's been about the heart I would say foremost So you know i. It's been a long time coming. And i think we made tremendous progress but also Engineering approaches of quietly made a tremendous progress. Just a few weeks ago. A team at duke duke go blue devils became the first in north america to implant this new generation artificial heart in a thirty nine year old. We're all working toward the same goal of course. But i'm asking you because you're the endogenous sal guy do you think. The ultimate solution will be a matter of engineering or cells or alternatively engineering and.

heart attack harvey harvard duke duke dodge north america
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

02:48 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"So i gotta ask you know what's what's next. We always talk about how one day we might be able to harness this regenerative capacity for heart regeneration in humans but we still have to figure out in the realm of zebra fish Regeneration before we can actually translate some of these findings to mammals. Yeah that's a great question. Thanks for the kind words While field has exploded to say the least We first started cutting pieces of hearts off. Zebra fish twenty years ago. And now they're they're they're dozens of groups. Claimed my former trainees running laps Setting heart regeneration zebra fish around the world there. There are many dozen studying other great models like neonatal mouse heart and then even even many more were focused on trying to to pride and dot. The adult mammalian hard often in mouse models to to produce a better regenerative response. does naturally and so i mean if you ask What's left to find. Sometimes sometimes you can say you know. Sometimes it's it's it's You know it's it's it's hard to. It's hard to predict where i think we're at a time where many of the the key findings were going to back into. Because there's there's so much activity in the field. You mentioned some of the some of the important ones. I think it's critical to have a consensus that heart regeneration into natural sense. And i think most likely i think most likely in it's it's translated. Applications is about cardiac myocytes dividing in fish produce. It's the Well understood mild heart regeneration. We now and they're probably best data of any system that we know at least has looked at in laboratory. They stimulate cardi myocytes divide muscle cells to divide in that that produces the new muscle in in adult So it needed neonatal mice this is also the case and in adult mammals. It's very much in my view. Most likely the case that we have to figure out how to get a small very small cad population of muscle cells in an injured. Mailing heart to divide with the proclivity that Zebra fish have that neonatal. My my step. I think this is this is key. This is a central finding to to.

neonatal mouse heart
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

04:04 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"Who has an imaging and a more quantitative background certainly To to take advantage of what molecular engineers are innovating with signaling reporters or or centers ways to quantify live in vivo populations of cells that activity You know just like erc as well as others. to to have live rita gene expression and then You know to to have two platforms to image those to capture what again thousands of cells are doing over a period of hours or days or weeks and then kind of synthesize stack quantitatively and try to understand what it means and very recently. What what we found just an example of something surprising is that when we when we pluck the scales zebra fish brazil. They grow back quickly Within a a weaker to obey very robust regina process. And what we find it if we image the osteo blasts the main the main cell population abound depositing cells if we we image them with a with a panel of reporters a look at erk signaling for example We see that this signaling pathway during regeneration as a really fascinating pattern of originating at high levels in the center this regenerating scales it can grows into a bigger and bigger disk and it radiates in a in a wave of fire activity. Across from the center to periphery than another way begins at the center again and radiates the prefer. This happened six or seven times. Any each of those ways is associated with a burst of growth. As the wave goes through these osteo blast that ring of sorts undergoes a burst of growth and then stops and so i mean it's hard to explain needs without videos and images but i think my point is that by visualizing things that higher and higher resolution we can we find things we never would expect expected to be involved with regeneration like growth of This these scales is is controlled by wave. Soap up signaling. Rather than princeton's a single source that produces a factor that diffuses and controls growth in up on a more traditional sense. Yeah for picture. Says a thousand words video says a billion. And that's i mean. Honestly that's one of the reasons of always admired the work coming out of your lab. Because this visualization it leaves little to the imagination but also had boost your imagination reich and serve as a source of inspiration for people aspiring to do their own incredible microscopy as trainee. You know somebody who's training duke. This was something that i had no idea. You could do. No idea you could actually visualize development at that kind of way. So it's It's a beautiful thing and for the trainees out there listening. I would really encourage you to take a look at the post labs work. It's really exceptionally beautiful. Imaging so let's get a little bit deeper into the cardiac regeneration side of things of course established during your post doc. That zebra fish is a tremendous model for cardiac regeneration. And show that you can actually injure a significant portion of the zebra fish hearts. And it's still gonna grow back through division of existing myocytes inability. that's not obviously found in adult mammals. You know something or hoping to harness. Maybe one day down the road. In over the years you've shown the importance of the epa cardi. I'm actually to the regenerative process and as we talked about. You've used amazing microscopy to map out cardiac regeneration in zebra fish..

rita gene brazil princeton epa
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

03:16 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"And understood that this could radiate out to other tissues let leichhardt regeneration for example and From from then on essentially more and more people began recognizing the power of the fish and its ability to regenerated spinal cord and hard retina and fins and other tissues and that. There's a great chance to use genetics to to to to to get this really important problem. Yes i mean. I'm a i'm a big fan of the lower vertebrates for elucidating. The mysteries of developed the biology's. My doctoral training was with xanax. I mean not famous for genetics or regeneration but still i think a powerful system Really because you can observe development x. Utera outside of the black box that is a uterus and seeing really is is is the key to a lot of insight you know direct observation but was ziv efficient particular. Microscopy has been really heavily leveraged on your own work was among the first use rainbow in the fish to establish the principle of colonial dominance. That was almost a decade ago. What's the latest way that your group is using tack imaging to visualize heart or other development and or generation it hit on something dalen I'm really excited about that. That is the ability to to image regeneration now just grossly to tissues growing but as populations thousands hundreds of thousands of cells now working in some coordinated mechanism to do something really complex Really interesting so So imaging regeneration at higher and higher resolution is is is really important and and your rights. superfish Have a lot of advantages of their size. Some of the transparency their their tissues the ability to make a reporter strains senate Just to make on a a large panel of transgenic animals that low cost and a relatively small space. So i think that you know. Some tissues are a real challenge for imaging at Subtitler levels the heart is insider swimming animal. It's it's constantly beating the image heart regeneration at the level. We all like to challenge. But but if you look at the surface of the fish there's a there's opportunities and so thin regeneration the regeneration of scales and of skin retina can be accessed until what i'm excited about in what were implementing and. This is in close collaboration with my colleague. Stephanos talia Also at duke..

dalen senate swimming Stephanos talia
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

05:10 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"Jeff is so critical it's cancer angiogenesis and this is in fact what. I studied as an undergrad duke. While studying angiogenesis in in the context of endothelial cells and importance of of signaling egypt. Signalling to to regulate all that. If you're taking these pills and you already have. Some propensity developed cancer or some very early stage cancer. My fear is that the blood vessels and the angiogenesis in that. Tumor is gonna skyrocket right. Isn't that the fear. It's it's straightforward. Think not for you partner. Your vessels are fine. You got your clean brother and you. You're young like a cherub. I don't know what you're talking about this past year. But i'm looking you in the in the screen here and you're looking fine my friend. Don't take the veg f. You don't need it but You know some of you out. There may need something else. Some other side kinds. And i've got a message for you from stem cell technologies. That might be able to help you with that. Activate expand and differentiate yourselves with cited kind chemokines and growth factors from stem cell technologies. These reagents are validated to ensure reproducibility across a variety of applications for immunology stem cell research explore more at www dot stem cell dot com slash site. A kind spoiler alert. You're not gonna find any bej pails there so don't bother looking now. Let's get to this interview with our fellow. Dookie dr ken poss- or at everybody. We are here with dr. ken pause. Who is professor of cell biology and head of the duke regeneration center also president of the newly founded international society for generative biology. Dr pastas lab studies the regeneration of tissues like heart appendages and spinal cord and zebra fish model system. Has i have is established. Many new concepts and mechanisms of tissue regeneration including the discovery of zebra fish heart regeneration and tissue regeneration enhanced. Her elements can thank you so much for joining us today. Thank you for having made great great to be here. Check two guys yet. It's a pleasure to have you join us on the show. Dr poss and i've been a fan of your work. Ever since my days. Undergrad duke and in reality..

cancer Dookie dr ken poss Jeff egypt ken pause duke regeneration center newly founded international so Dr pastas spinal cord Dr poss Undergrad duke
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

05:34 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"Wow i author is m grunwald and this is coming from the lab of dr tesha over in israel at the hebrew university of jerusalem. And we're talking about jeff. Were talking about an application of of for enhancing aging. So we know of course. The body relies on blood vessels blood vessels control and deliver nutrients to all different tissue types in the body and oxygen and all that good stuff and unfortunately we're all aging all right. There's a that's a fact of life. I know i'm definitely aging of accelerated aging in the last year by a factor of. I don't know how how much there's a lot going on my life. I was just leave it at that. But i can certainly benefit from a way to reduce my accelerated aging and perhaps best jeff is going to be an influencing factor in that the crux of this paper. Is they basically showed that veg. Eff is really critical during the aging process. And although veg production is not necessarily reduced during aging in mice this a mouse study a longitudinal monitored vegf signaling and they saw that signaling is reduced in multiple key organs and this is actually associated with the increased production of soluble betcha for A soluble vendor sceptre. Okay it's generated through an age religious shift in alternate splicing of the are. Mri and its functioning of trap. Okay so this. Vegf trap is reducing the traditional of signaling. That's happening in over the course of aging and what they did here is they increased really straightforward experiment. In my opinion they increase the circulatory veg f using a transgenic veg of gain of function system. Or an av associated of transaction and they maintained a quote unquote more youthful level of signaling providing protection from age related. Capillary loss writes that that makes sense to me. More veggies means more capillaries than a healthier vascular toner vascular system. I guess more capillaries out there and because of that so that led to a bunch of different aging hallmarks being altered and again assuming a more youthful state including mighty conrail function metabolic flexibility to sell senescence.

m grunwald dr tesha hebrew university of jerusalem jeff Eff israel
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

04:23 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"But the it's known that In vivo the the the regenerative capacity of the liver is not just a cell intrinsic capacity dependent on this crosstalk right between apathy liam and the micro environment we talk more and more about the microbes than niche and its role in regeneration And in the liver the contribution in the microbiome Are the niche To regeneration of the ductile cells. It's not really a described pretty pretty poorly understood all right And part of that is because the systems are in place you know. We're doing very well with the organiz but to date. There hasn't been a organized that incorporates both deductible cells and mezin kimmel cells of the models are very epithelial centric. Right so here. Mary and her group. They i stay described. The sub population of kerry puerto mezin 'time cells that are defined by. Pg fra positively and scott one positively And then they go on after identifying to show that These cells control proliferation of the duct epithelium And the way they do that. Is that the ductile epithelial. Proliferation is either induced and sustained or totally wiped out depending on the degree to which the deceased as duct epithelial so..

mezin kimmel kerry Mary scott
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

05:13 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"Hfc's and deciding what they're gonna turn into okay so the tia. Phoebe media induction of this end life Endless pathway is triggering membrane. Receptor degradation and this is limiting the metabolic activation of hfc's and this is leading to quiescence himself renewal on the other hand mic known for its role. Often cancer. right is actually i. It's doing the opposite so it's engaging these acted biosynthetically processes will actually repressing the license metabolism. And it's driving the activation of the. Hfc's okay so it's like a yin yang kind of thing and they're figuring out here that there is this dichotomy right there. If e b media to control the license home as a way to regulate stem cell fate determination. So i like this paper. Because i'm i guess i'm old school. I don't know that much about the license home. I do know that it is considered to be the trash can of the cell right but there's a lot more to it than that. It serves as a really important signaling. hub for hse activity and hse quiescence in particular. I mean i so exhausting biology. There's just so everything. Does something like a thousand things and every one of them is for reason. How can you keep up. But this is a great example of that. And i. I like that it makes sense. You know. this is one of those great feelings about when you get in science you making observation. You unpack a bit of the mechanism and it all makes sense. You know you solve the puzzle. John dick does this. He's been doing it for you know decades in his career and this is another story that but if you're him i guarantee you're just exhausted because you're like okay. Here we go. I cracked open another nut. And i'm looking on the horizon here. And i don't see an end in sight but i'm sure he gets the joy out. I just shat also here. Tim schroeder on this. I love shroud and when it comes to the you know the single style and the monitoring..

Hfc Phoebe cancer John dick Tim schroeder
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

05:12 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"Yeah it's going to be a a repeated topic in this particular episode of the podcast. We're talking about model systems. Nontraditional model systems. Perhaps you know we're gonna talk about zebra fish with dr poss- down the road and here we're talking about see elegance which has been a workhorse in developmental biology for for years. Now i see. I learned about it. In my undergrad at duke caboodle The power of the the cio agains zim part. You know every single cell in that organism has been mapped. Okay you know..

dr poss
"poss" Discussed on The Stem Cell Podcast

The Stem Cell Podcast

05:28 min | 11 months ago

"poss" Discussed on The Stem Cell Podcast

"One ninety nine stem cell regeneration in zebra fish doctor and everybody we are day-long loan and a room. Welcome back to the stem cell. Podcast where we culture knowledge and stem cell research by talking to some of the brightest minds in the field. The stem cell. Podcast is brought to you by stem cell technologies a global biotechnology company supporting life science research and fostering communication and collaboration in science. Today we have the esteemed scientists dr. Ken poss from none other than duke university. He's on the podcast to talk about his research on the regeneration of tissues in zebra fish. We've also got our usual roundup. Recent highlights and stem cell news. Coming up let first. Are you on social. Media should you. Should they be watch. Stem cell technologies christina mcburney manager of scientific communications and lana bedell manager of social media. Discuss how you can use social media as a scientist to advance your scientific career on demand. Webinar learn more at. Www dot stem cell dot com slash social media my man. I'm on antisocial media. Which is the lurking side. Just lurk. i just look at other people's posts are right so don't tell me what to do You know th this episode is a little bit Outside of our comfort zone you know. We're talking about endogenous stem cells and regenerative process That were there. You know not not grown in a dish from pluripotent stem cells. And i'm excited about that for one For the roundup. I'm gonna kick off with the study. That's also outside of a comfort zone terms of models. We usually like to go at the mice or not. Just something here. I'm talking about the worm. Not even a vertebrate But this is. I think a story that really. It shows the power of engineering When applied to systems biology. And i think there's a lot of lessons from this that we can apply in vertebrates even maybe humans So this is a story. Like i said. It's about the worm. And it's based on this idea that you know all development biologists the holy grail released understand how this single cell zygote differentiates into all the specialized cell types that make up the tissues and organs of an organism's about In in nam towed are in seattle against nato right It's it's a boom. Because the entire cell lineage has been totally..

Ken poss christina mcburney scientific communications lana bedell duke university nato seattle
Europe's Summer Tourism Outlook Dimmed by Variants, Rules

AP News Radio

00:52 sec | 1 year ago

Europe's Summer Tourism Outlook Dimmed by Variants, Rules

"Europe's tourism industry is suffering more set backs is chaos and confusion of her travels and restrictions tosses another cruel summer for the industry a surgeon Kevin nineteen variance is threatening to derail another summer holiday season throughout Europe popular destination countries throughout the continental struggling to control the spreads in France the world's most visited country visitors to tourist sites are now being offered a special cabinet nineteen poss to get the past people must prove their by the thirty vaccinated or put Houston negative virus test is needs introducing a similar pasta access museums and movie theaters and many other public venues the move caused outrage throughout the country's came out to protest in the past several major cities Europe is vital tourism industry is in dispatch as tourist arrivals plunged lost him by nearly seventy percent Karen Thomas London

Kevin Nineteen Europe Confusion France Houston Karen Thomas London
Nadal Knocked out in French Open Semi-Finals by Djokovic

The Mini-Break

01:58 min | 1 year ago

Nadal Knocked out in French Open Semi-Finals by Djokovic

"Unthinkable has happened rafael. Nidal knocked out in the semifinals of the twenty twenty. One french open novak djokovic delivering one of his finest performances. Add a grand slam in his career. Of course now. He's got the chance to capture his second grand slam title at the french open. Become one of only three men to accomplish that in men's tennis history. Of course he still has one match to win that match going to be against to. Ct paths who reaches her his first grand slam final of his career. Earning a five-set victory over alex sierra of a fantastic day of tennis in the books of course we still got two more to go here at the twenty twenty one french open as our women's singles final takes place tomorrow are men's singles final takes place on sunday joining me on today's podcast to recap all of today's action preview. The women's final also offer our initial thoughts on that men's final as well. You know him as our do everything. Here act cracked rackets. Forefather of the forehand slice the only undefeated high school tennis coach in missouri state history. It's james foster. Mcdonald's jamie seven hours of tennis in the books how you feel in my friend Not as tired as an adult but Pretty tired pretty tired knocking lady. I got up early. I was jazz. I was energized for the day. It did disappoint. it was good as good. No the quality of tennis from start to finish. Even if it was indulge in about twenty minutes really those first two games immediately put to shame the entire quality of this year of c t poss- match. And i will argue to the dying day that that's your fear of ct post-match much like this fear of t match was better than the consensus seems to be surrounding at but the quality of joke vich even though noodle hadn't played his best tennis. This felt like the first time we've seen novak joke which his absolute peak in quite a bit of time. Maybe even in this entire season

Tennis Alex Sierra Nidal Novak Djokovic Rafael James Foster Mcdonald Missouri Jamie
Hakanpaa scores to lead Hurricanes past Predators 3-1

AP News Radio

00:31 sec | 1 year ago

Hakanpaa scores to lead Hurricanes past Predators 3-1

"The Carolina hurricanes used a balanced attack to take down the visiting Nashville predators three to one Jacob Slavin scored his second of the year at the end of the opening frame before predators captain Roman Josi tallied his sixth midway through the contest the tie things at one trade deadline acquisition jadi hawking poss or dist first goal in hurricane sweater halfway through the third to put his new club up for good of national goaltender you sauces forty five saves twenty three came in the first period alone sixteen Carolina skaters registered at least one shot on goal I'm Jeremy cake over

Jacob Slavin Captain Roman Josi Carolina Hurricanes Nashville Predators Jadi Hawking Poss Carolina Jeremy Cake
Libsyn buys podcast ad company

podnews

00:40 sec | 1 year ago

Libsyn buys podcast ad company

"Contest lipson are so acquire advertise cost a podcast advertising company for thirty million dollars last year. Advertise cast bought in twelve million in revenue grew forty five percent. We expect to generate meaningful revenue by offering the advertise costs solution to lipton's customers said lipson president lori sims in acquired podcast creation platform poss in february. And this more succumb lipson has also raised twenty five million dollars in funding to pay for the advertise cast acquisition and to provide lipson with additional capital for other strategic acquisitions

Lipson Lori Sims Lipton
Choosing the right course for you

Course and Career Chat

08:33 min | 1 year ago

Choosing the right course for you

"At the moment i have a five year old and if he asked him what he wants to do he we'll tell you that he wants to be a fine and a builder and he's having trouble understanding that you could probably do both of those at the same time but when you were five years old what did you want be when you grow up excellent question. I think was a handful of different things that i was interested in very very different to what i've decided on his show. Yeah i think at one point. I wanted to be an architect. I'm very into my crafts and getting a bit creative so that was one of the options. My mom was a hairdresser as well. So that was another thing that i wanted to pursue. Think i still would like to do that on the side verb. If i'm really that's yeah yeah. It's changed a lot over the years. Pabst eating as well which yeah rain. Good to have a chat to you back in the day. That's okay. we can still chat whenever you want. It's interesting isn't it like when when kids a little. They obviously only have a small experience of what jobs are out there. And like you said you know your mom was a hairdresser off and not taking another one. That's what i wanted to be. When i was five and then went away from it and then came back to it so just interesting as we get older and we exposed to more different careers and things like that that we get some different understanding about what we might live today. So let's let's forward from there and go to yet ten so i'd like to find out. What sort of student were you when you were india. Ten and starting to think about vca and what subjects you liked to do. So y- attend. May was i think i was about to move schools so i was very studies focused and think i'm a little bit. I say day with how. I like my notes and that sort of thing is very much focused. Yeah my schooling. Liked it a sport as well. So that's what. I was a good outlet as well to keep me bit balanced. Yeah it is good to have that that balance particularly i reckon going into. Aca find lots of students decide at that point that they're to create spot and it makes me really sad because i think that it's it's such a good outlet win. You actually really hot to go out. And you have iran or place a bowl. Whatever it is that you do. Did you find as you were going through. Definitely something that practical israel. I think we've oh sort of come to realize that especially with lockdown recently. How important it is to get outside and get some sunshine and well to break up the day. Yeah absolutely so. What subjects did you end up choosing. Vca yes say nba say. I did maths methods. I did. I thought i was going to be doing special because i did love maths but didn't end up doing that. I did chemistry biology english and french. Actually okay great. Yeah and french's that's an iceland to have in there is all. I actually did quite similar subjects that deep german instead. And i find that people often he the combination and think. It's a bit weird. But i really loved having like that. Language was just different to the math and sciences and Did you have that with french. Slow i think science. I think after doing it for the four years. It was sort of like. Why wouldn't i continue on. And i think it really progresses in basie a and that's when it can really be used become useful when you decide to travel later on yet awesome. Sorry at that point in time when you were choosing your subjects. Did you notice or like way you are now. Did you have an idea of what you would like to do when you school. So just a heads up as you would have head from kinsey tribe side to do medicine. I think i had thought about it at that point so it was in the back of my mind but i don't think i was one hundred percent that that was what i wanted to write. I think I knew that. I loved maths. I love science so that was mainly my goal is at that point just to continue on with that and sort of kepa arpan to decide a bit later on yet. And that's that makes sense as well like you say your if that's what your strengths lie. Sorta the advice that i try and give students. If you follow your strengths and interests you'll end up being able to do courses that you want to if you not into maths and things like that thing there's no point following them too much because the courses that you wanna do require it and vice versa or if you do really like it then you should do it because you'll end up using it later on. Sorry so we face the you're doing those subjects. How one's vca did you. Did you go through it really easily. Did you have some ups and downs. What were the those two years. However they view i think yes so basically for me was a little bit challenging actually mainly at the beginning i had just moved schools. That the static year eleven. Sorry i grew up in Ever of school and it was very much focused on sporting whereas when i moved to the suburbs it was more academics. I think goes a big wakeup coal. To say i guess the competition as a whole and with basie a for instance. I had to repeat my math methods. They hit advised me like had a discussion with me that i think that was the best sort of route for me to go down and i think hearing. It's you feel like that's horrible. What do you mean. I have to repeat it like thinking that i was completely fine before that with mass and something that i had always been i guess gifted or was my strength so i think that was a really good learning experience to say that while it was hot to hear. It was the best thing that i had done. Oh that i could be in terms of preppy maitha really optimizing my busy in the following year and year twelve. It is really good as well at the school recognized that and and gave you. That feedback allows you to do that. Really early on said he just moved to the school so for them to make that call really early to make sure that you were really well prepared but as you say it's not it's not easy to hear that kind of thing and i imagined as a student at the time that was quite difficult also really glad you mentioned it because i know that i say lots of students asking about what sort of what sort of percentage they need on saxon things throughout the year and what i heart. People will understand by the example that you've given is that different. Schools have different standards of assessment within the school. And that's why say works the way. It does with the focused more on the exams because they're external and in this the sort of scaling of the subjects or the the study scores within the schools to make things more. Even so yeah. It's good that you highlighted that that can be different at different schools. It's very interesting interesting experience. I think yeah and a unique experience lot substitutes wouldn't wouldn't get that they wouldn't understand the difference because you most units are at one school move. Aca so yeah. It's an interesting insight that you had okay. So what tepes would you have the current students. What are some things that you did in year. Twelve or that you wish you had done any twelve to make life easier. Sorry i think something that. I still try to constantly. My studies is goal setting. I think that is sorry. Bake i think especially students that would have just gone through lockdown realizing how day can poss- without getting a whole lot done so just having go set in the morning to take off and yeah just feels good. You can take them off and you can say that you've been productive throughout the day as well while not not being hot on your south on those days where you had a good day and yet just waking up the next day saying how can i be better. Had i do better than the day before and now the thing is i think yes. Sorry to interrupt. But i think that is so important because i think it's really easy to think about all the stuff that you didn't do and you didn't get done whereas economically somewhat. He did get done. And then as you say if you do have an off day what can get done the next day

Pabst Kepa Arpan Kinsey Iceland NBA Iran India Israel Basie
Biomedical Engineering and Medicine - Off day

Course and Career Chat

00:41 sec | 1 year ago

Biomedical Engineering and Medicine - Off day

"Sorry i think something that. I still try to constantly. My studies is goal setting. I think that is sorry. Bake i think especially students that would have just gone through lockdown realizing how day can poss- without getting a whole lot done so just having go set in the morning to take off and yeah just feels good. You can take them off and you can say that you've been productive throughout the day as well while not not being hot on your south on those days where you had a good day and yet just waking up the next day saying how can i be better. Had i do better than the day

Sarah Today Four Years TEN Two Courses Two Years One Hundred Percent Five English Both India Mccutcheon Five Year Old Five Years Old Israel Year French
The Mystery Of Hudini

True Mysteries of the Pacific Northwest

06:02 min | 1 year ago

The Mystery Of Hudini

"Welcome to kids myths and mysteries from around the world strange and unexplained people places and events often forgotten by history or loss in the midst of time. I'm kit chrome today. Harry houdini to understand houdini magic. It's important to understand the man born eric. Weiss march twenty four th eighteen. Seventy four in budapest hungary. He moved with his family when he was four years. Old to new york. And eventually migrated appleton wisconsin in his youth. He was a natural athlete and had a fascination with magic and adopted the name. Houdini by adding an eye to the last name of his idol. French magician robert who din although there was a gimmick or special effect too many of his escapes. there were those at pressed him physically to the max one story a story mind. You is that of an underwater handcuff escape. Depending on who you talked to. He was in a box. A straightjacket or manacled hand and foot anyway. The story goes that he was in chicago in winter and had a hole cut in the frozen river that he stepped through not taking into factor that the river flowed under the ice easily escaped his manacles but was swept downriver. Above the shivering crowd eventually dispersed fearing that they had witnessed the drowning of the great magician under the ice. He moved from trapped air bubble bubble eventually finding his way out. There are dozens of versions of his story but whatever the case demonstrates his power of concentration. Above all harry. Houdini was a showman dangling from cranes. Skyscrapers upside down in a straitjacket. He would attrac- upwards of fifty thousand. Onlookers necks craned as they watched the dramatic escape. This would guarantee a pack theater that evening but he was always searching for a new effect. He's responsible for bringing the obscure thread the needle from india to the american stage. This is where he would placed dozens of needles in his mouth along with thread. Poss- drink a glass of water then amazingly extract needles threaded with enough threat to cross the stage later. He performed the same illusion with razor blades. Houdini was much more than a magician however he was a man with an insatiable curiosity and was fascinated with movies made several including one where he was to rescue the ever suffering female from iraq on the brink of niagara falls. She was harnessed to a safety line. Houdini would have none of the safety features offered and was nearly swept over the falls. He got out of the movie business because it didn't make money. He was also fascinated with airplanes and in nineteen ten. Was the first man to fly a plane in australia. Sailing for over three and a half miles. Houdini died at one twenty six. Pm tober thirty first. Nineteen twenty six. He was fifty two years old. He was a man who was driven. You might say by the slogan. The show must go on but also by his own physicality take a look at the old newspaper photos of him in various stages of escape remember. This is long before photoshop notice a developed biceps quadriceps and shoulders however by late forties he suffered from appendicitis attacks and on several occasions had to be helped off stage by age fifty despite more sophisticated special effects his performances required longer periods of recuperation is said that he was backstage reclining from a broken ankle from a previous show won a university student questioned. The magicians boasts of the stomach of oak remember. Houdini was fifty to the student. Delivered a series of blows stopped when. Houdini claimed he was not able to stand to prepare for the strikes. No one knows. If this cost the appendix to rupture hours of the event. Houdini went on to perform with a temperature of a hundred and four. Eventually he entered the hospital where he felt. Recovery was eminent but at the end he was heard to say. I'm tired of fighting. Harry had two loves in his. Life is wife bests and sell you steiner weiss. His mother when she died in nineteen thirteen. He visited select mediums in an attempt to make contact with her from the spirit. World appalled the frauds who claim to be able to make contact. He went on the warpath exposing psychics. Fortune tellers mediums and in the process and raging. The industry is most outspoken. Opponent was the blonde. Which of lime street strange seems her. Spirit guide walter in one thousand nine hundred thousand five said that. Houdini would be dead within a year but houdini had devised a code. That only best would know that if indeed there wasn't afterlife he would contact her using net code. The stories surround this aspect of his life and the code between he and his wife would take ten podcast to explain it to say that he did not connect with best using the code. Each halloween for at least four years after his death she would lie to candle. Hold a seance. She continued the sales which involved a candle said to have burned for ten years. It was a nineteen thirty six ten years after houdini. He's passing that. She handed off the candle. And say on tradition to walter. B gibson friend confidante ghostwriter for. Houdini gibson was also the original author of the shadow mysteries writing under the name maxwell grant late in his life. He passe on tradition to magician. Dorothy dietrich who now burns the candle. Every halloween while conducting a seance seems. Houdini is yet to

Houdini Harry Houdini Frozen River Appleton Weiss Budapest Hungary Eric Wisconsin Robert Niagara Falls Steiner Weiss Chicago Harry New York Appendicitis India Iraq Australia
Remember When? 2020

No Challenges Remaining

05:52 min | 1 year ago

Remember When? 2020

"Is interesting for me again keeping the remember when like personal. This is where we spend a lotta time. We're we no longer see it as player in the flesh for the rest of the year. Either of us since where it becomes it's very divergent path right that from here on where like a one hand like. I'm not leaving home. Match like we have like a night of looking like may fifth rewatch korean baseball together and adopt the nc diagnose diagnose in the how camps dyno's jeff passan his pinkerton behind him and stuff like that. So we're on our own and you know doing our own. Things have watching not only connect. Whatever we're doing to keep ourselves sane afloat and tennis players meanwhile are like having these very different ways of coping. Go various out most of them. We don't hear from at all right muslim. Just go off grid. I will say that that's absolutely true. Most of them have just shut off so the ones we hear from early the outliers right but also larger the more prominent in late april or even it was late. March was already in march. Like it's poss- put up this flog of himself alone. His monica apartment. Where in this yellow raincoat is like stream of consciousness thing where he's like losing his mind like he doesn't know how to function he's also like not with his family that's sort of like argument or something in their various flares that we saw earlier in the year with mentioned that. Adp cup saying like his mother like you know the him at a press conference basically so he's on his own journey there and like some the first things we see some of them are really positive like we see like venus williams during this year's one of like sort of a low key like warning actors like bit role but like remember remember when venus williams got greek or damaged optic flasher. Exactly what i was gonna say. What a queen. Venus harass gregoire showing ads dramatically colossus the ground in performance ecstasy and. It's just a lovely moment of venus is like having a really you know again. I felt bad about similar to the fire. Donation topic like rating people on. How they're handling this thing. But like venus is somebody who like really like seemed to be like at peace like really opening up being way more talkative than she had all year like. There's one of the things. I found him looking. This is skipping ahead like lexington. She does like after she beat via. First round gives this unbelievably a few sive. Chatty postmatch interview. It's just been so mike which is like for the last several years in terms of what she's like in not being very revealing a reticent to share too much open up too much has been very different venus so we have that now the other hand we have things emerging like you know. Say this the novak djokovic stuff where i quietly. He's talking about or on a certain serbian channel. He says things that are if not definition of what we consider antitax at least vaccine. Skeptical in vaccine. Chilling say. I don't know exactly what to put in. Then he touching these instagram wives which you know venus is doing flirted with record time of the people in and and and if only judge just flirted with dmitrov harmless he could've done it was right therefore with an option. This is the college novak where instead he by early he was doing his a few instagram's With turbine jafaria wellness grew guy to joke. Which is somewhat credit. I don't know exactly what happened here. They stopped by mid mayton one more. After basically i people started started combat. For what ridiculous nonsense being spewed in them so we just all tennis players like what a tennis player was tennis star celebrity without the thing that makes them why we care which is tennis. Excellent right and we're left with these pictures of people who stop paying their coaches right away was a big theme like all these top top players stop paying their. That was a really big. That was a really bad really was mentioned a few times and it really explain like because you you learned about it and yes no. I know. I was really struck by how within days. What was it like before the week of in usama. How fast set move your mortgage. That players immediately. Cut off the payment to their coaches who they are the sole employers of in there not not almost all like Every coach was estimated was more than ninety percent of coaches. Weren't getting paid at this point. It was it was. That's fine but i'm just saying when you say that oil like ebay. But but you'd only coaches were not getting paid and it just sort of like selfishness of tennis players end. We see tennis players as being very focused in very driven motivated and in this pandemic must have a crisis a lot of times that revealed that turned into self centeredness self-focused self-centeredness turn to selfishness. Turn to lack of care for other people right and to me. I saw this sort of across the board cutting off of the payroll department of their personal tennis. Teams their coaches who are people who invest their whole careers in helping you do well. The second you stop getting you missed one check. They get cut off and a lot of these players. Have making lots of money. Didn't have to bisley anyway. It me the wrong way seeing these these athletes granted. They're not in a fixed salary. They were not getting guaranteed income but for them to immediately cutting people's pay very quickly and even like occasionally federation like tennis. Australia started for furlough employees very fast and that bothered me a lot too because they had a full twenty twenty australian open and they had a folk coffers and they i think by i dunno april or so. They're already furloughing employees. I thought that was crazy. And they're going to be painful full prize money in if they go it in whatever a lot of the mountain workout and just a lot of a lot of. I was getting various enchanted with tennis and tennis players tennis players because there was no tennis but tennis players were not impressed. Me overall with their conduct. Yes you had venus doing

Tennis Jeff Passan Venus Williams Pinkerton Dyno Gregoire Monica Baseball Lexington Usama Mike Ebay Australia
The Move Slows - Bitcoin Consolidates

The Trader Cobb Crypto Podcast

02:16 min | 1 year ago

The Move Slows - Bitcoin Consolidates

"Consolidated. That's basically what we've done bitcoin. Well it seems to just be sitting on. I we building building building. You know the consolidating about Thousand for the most part so it is it's also ryan rights. It's starting to build these types of ryan's is that it builds precious of you have been through. The bitcoin breakout area of the become a moscow. So we do. You can think back to that. Think about that pressure cooker. The high love is coming at the resistance. This their resistance is in a flat level. In this case. It certainly the old highs and twenty thousand for us breakthrough twenty thousand won't thing i to through momentum. That's what i'm waiting for. That's what i'm hoping full and with this consolidation that we've got rotten now giving the moving averages tom it catch up a little bit giving the market a little bit of time to build and build and build so that pressure continues to to pressurise. Homages gives us a much better probability of does breakthrough twenty thousand that we do see a fairly explosive move now that in saying that we have to revert back each week due to that weekly chart as well now at las wake. The bitcoin shots closed up six point. Five percent so closed up. A guy at is not too far for it's moving average. Even of course fact. The candle closed. It dragged those moving averages up with it. Sorry ten period moving averages hanging around some which is about sixteen thousand and the twenty periods. Just above fourteen thousand. There's well so anywhere between sixteen. Fourteen would be prime place to pull back to if bitcoin is to have that. David weekly pullback which is very likable sessions right locking that there's there's a hop ability that does occur if the consolidation doesn't continue and we push thirty twenty thousand that is very much on the cause to see a bit of a pullback leading into the end of the year and my goodness. Hasn't this gone past. Well the the laugh about Is poss- quickly will have you and your family and friends at saif wherever you are in the world but we certainly sing consolidation not quick. Pull back

Las Wake Moscow Ryan TOM David
Dan's Plan For A Dam

Bedtime Stories With Nennis And Douglas

05:17 min | 1 year ago

Dan's Plan For A Dam

"No story is cole. Don's plod for read rite. A douglas won't of don's favorite places to explore a merry toll. Eames which turns off from the river. Gurgle gloag about half of oil west of horse. Small lana poll and runs. Poss- mr harry's war meal where it pushes against the potholes and turns to big oil and helps growing the core or roll the pay her or spin the thread and then it continues through. Alexy's palmed ends in bobo. Yoke swum maritime stream is fulton because although it starts widened foster enough to power a war to mail a few follow wit eight soon becomes narrow enough to jump over with a rayleigh. Big leap consume lower enough stunned on a hot day or sale baked dixon unprotected their ships and on top of their own manny animals to be found living along the banks water. Voles autres stopes eight hour. Weasel cold wilbur. D watts more there. Pull the soy's if a car where the stream split satan to arrive which you couldn't jump pon to on coal your own kingdom don could spend the whole day play in in maritime stream. Eva notice the sunset sets a but on this particular day. That son had barely risen. Why don got to the stream walls lovely warm day but yesterday that been a rainstorm which men even more water than normal had rushed. I've lumber stock mountain and into the bathroom. Gurgle gloag and even more water than normal had been pushed off to the soil lead into maritime stream at was russian on swirling on bogelund pas. Mr hirees walter mail and even wear it gots lower and narrower it was still surging on spin it around the rocks and flowing happily passed the little spend about an hour finding the big a specs he code and throwing them to say how quickly that they pushed down stream more on more stakes got thrown in solve of done so large they were really branches not stakes until he got bored of throwing and soya date to walk down towards alex says paul and half wave he no taste that's hot begun to form a new poll and all his steaks and broad shays hot clogged off one of the little boots around warm small all off the water couldn't get through this gave done of brainwave gets beld i'd die hey said to himself on gun russia collecting as many pieces of what he could find on the riverbank or in the nearby trays. Babysitters mike dodd muttered to himself as the dragged a huge log over to the stream on pushed it an on going to build a dom back than any beaver ever day spa. How many steaks logs. Hey put into mary stream.

Gurgle Gloag Mr Harry Alexy Eames Mr Hirees Walter Cole Voles DON Wilbur Dixon EVA Shays Alex Mike Dodd Paul Russia Mary Stream
From End Sars to End Swat, Nigeria protests explained

The Takeaway

05:30 min | 1 year ago

From End Sars to End Swat, Nigeria protests explained

"It's been more than a week of protests against police brutality in Nigeria tens of thousands of Nigerians have taken to the streets where police officers have opened fire on demonstrators and arrested hundreds at least ten protesters have been killed so far. Protesters have been calling for police reform and specifically the end of a unit that has been accused of human rights abuses. The unit is called the specialize anti robbery squad. Or SARS over the weekend the President of Nigeria said the unit would be disbanded but demonstrators remain skeptical and are continuing to protest until all of their demands are met joining us now is the BBC's Nigeria correspondent, my any Jones from Lagos. Welcome to the show Miami High Tanzania. So we said that people are protesting this unit but what was was there something that set off the protests to begin with? So the process initially started on early in October when a visual appearance to should meet the appearing to show some young men being dragged by a sales offices out of a hotel. It's unclear when the video was taken, but it was shared very widely on social media in Nigeria and started a resurgence in a Hashtag the had been seen in the poss which was. The HASHTAG and saws. This hashtag first appeared thinking twenty eighteen and had been used a couple of times before when similar videos had been posted showing solves officers allegedly brutalizing members of the public but this time round it picked up a lot of speed and this movement. This youth led movement that seems quite organic has emerged from it what types of policing tactics Are. Residents are Nigerians protesting and who are SARS targeting generally. So, Nigerians have been protesting everything from extortion to torture to extrajudicial killings. I'd be see that's Members of Saul's particularly allowed to act with impunity. on targets often young members of the public who? hops occurring mobile phones laptop they accused him of Internet's cameras The also occasionally target people driving nice calls and particularly they young female asking them how they made their money and they say that these practices are completely unacceptable and that they're taking advantage of their position as plain clothes, policemen to extort people for money. And and carry tile carry a brutal acts of violence against members of the public. Now, we mentioned that the president of Nigeria has since said that he would disband this unit but protesters are still wanting demands to be met. What specific demands are they asking for Miami Su they have a number of demands had a half five key demands they want all protesters to be released. Divest full justice for victims of police brutality who've been killed and compensation for their family they want an independent body to overseen investigation into police misconduct They've also asked for a psychological evaluation and training of members of SAWS, and they want to increase salaries for policemen across the board. Protesters have been killed by law enforcement ten people we understand so far has there been any accountability or. Justice for those people. So that's one of the key reasons why protesters is still out on the street despite the dissolution of sauce for them the dissolution does not constitute any actual justice for victims and they said the fact that people have been killed these protests at no officer has been charged investigations being launched. Nothing appears to have been done to that the forties and not committed to reforming police in any. Substantive Way and they said, they'll keep coming out onto the streets until they see some actual chain beyond just rhetorical the government beyond promises of reforms that they say they've seen before they want to see officers charged they want to see changes puts into law and wants to be assured that police officers in Nigeria would no longer be allowed to act with impunity. Let's talk a little bit about who these protesters are. Are they largely young people? Are they women? Are they men? Who are we seeing? That's taking to the streets that's what's been very interesting about this latest wave of protests. It's just the shit -versity of people who've gotten involved. You have members of the Nigerian DASS per sending money from abroad from the U S from. From the UK, you have young middle class people who live in Nigeria who educated abroad who are lending their skills be it's legal skills medical skills kills in logistics and organizing, and then you have you know ordinary Nigerians perhaps who've lived here their whole lives who are often targeted by the police because they seem as as powerless with not. So well connected all these diverse groups are coming. To a these protests because they say that the violence committed by south under underway to police because this is also a protest about abuses of police in Nigeria a whole affect everyone.

Nigeria Officer President Trump Miami Robbery BBC Lagos Saul Jones Extortion UK
A Chatbot with a Brain with Peter Voss, founder and CEO of aigo.ai

Programming Throwdown

07:30 min | 1 year ago

A Chatbot with a Brain with Peter Voss, founder and CEO of aigo.ai

"So I go daddy I focus focuses is on conversation assistance. So how does this work do you? Is it is it kind of like a a single assistant that you build many people use or do you have custom assistance for different? Consumers Yeah. So our product is actually now in a sort of second generation, we launched the first generation actually in two thousand, eight twelve years ago, and that we focused on automating call center calls intelligently you know everybody hates calling into a call center and having a robot you're not press one for this or. Doesn't understand you. So that's the market. We basically, these things are called ibaz interactive voice response, and basically what we offering in a company called small action is an issue with Brian. So it remembers what you said earlier in the conversation at that has deeper passing deeper understanding as some reasoning ability and so on. So much better conversation that was our first generation focusing on automating call centers. The second generation with Iggo. we just launched commercially last year here we focusing actually on on chat channels initially. Because as huge demand, that's the biggest sort of. Growth Area in customer into action and we are focusing on enterprise applications right now. So you know large companies want to give customers hyper personalized customer support also. Targeting things like a personal assistant for somebody wants to manage their diabetes. For example, for coaching we working with a company that that does VR coaching. And they basically need an intelligence engine to simulate the conversation that you're having so many different applications but right now focuses on enterprise working with large enterprise companies. Getting, into consumer market, we'd obviously love to have product available to to the consumer, but it's just very hard to break into that market. It's very, very expensive, very risky. So we choosing to I do. In a commercial applications. and. That makes and so so how I imagine isn't tell me if I've missed the mark but so so you go on. The Amazon actually, we did this the other day where we had to return something to Amazon and we had a it was a bit of a complicated return and says, he would you like to chat to your customer service representative and so and so we did and we this quick Chad within the Amazon website, and then they're able to sort of sort it out for us. Right as is kind of the market. Where you say if someone says they're going to chat with a person on on a website, but it's actually this bought and then at some point, maybe at hands off to a person needs to it's exactly yeah, that's exactly it and what basically we we taking that whole experience to another level because the current chat technology just has severe limitations for for doing things like that, and we will I think we'll. Talk at length about what does on why they are But yes, that's exactly the kind of applications we have, and moreover we we look for applications that are hyper personalized to the individual and what I mean by that is. Repeat, where it's more likely that they actually repeat engagement so that you can also have built on the loyalty of the customer or it's like you know just a diabetes management where you would actually using it every day but it could also be You know your your bank or or a company that you Amazon would be good example that you you may be interacting with on a regular basis and it gets to know you and it's hyper sliced to you as an individual not as a statistic of a demographic group but it remembers what conversations you've. You've had and. Take into account. It can use it as context what you said earlier what you said last week what you know what? What kind of interactions you've had before and that can be channel as well that that you know our conversations. Can Take into account convince other interactions you've had by email old know how the channels well. Yeah, that totally makes sense I. Mean One thing that I was thinking about actually when we were having this chat with this either customer service representative or a, we don't we don't know could we probably failed at turing test but when we were having this chat things I went through my mind was how? You know when I was, let's say early in university. TONS OF TIME and. So I wouldn't mind sort of. Like a kind of optimizing these kinds of things like, okay. Let's figure out the best way to do this. Week do different things we could try to for things like send us wine and if it doesn't work, then you will send it back and now. Things are just so chaotic right now there's just so many things going on you have kids have all these other people in the house and so. Now, it's like you know just send me all three things and we'll just pick the networks as time is much more important and. You know and that's an example of of where serve the customer context really matters because different people have different states of mind when they might be doing the same things as returning product and trying to get another one. Absolutely context is important. So even you know even if you. Talk to a human they I mean, they wouldn't remember what other conversations you've had. You know they might look it up in their CRM, but normally isn't time for them to to do that but with an. Intelligent assistant like like we providing it's. If you had a dedicated support person on the other side that actually remembers the last conversation you had a good example is you know for example, a telco companies will you might have problems with your cable or whatever. So you call your you had a problem and then you know suggested, well, try this try moving the router and put it in a different position or whatever. So you know next day you call in and then it can say, well, did that help you? you know and you say, well. You you reach I know you've already tried rebooting it. So we want to ask you to do that again you know and That's the kind of it's even better than what the human because you know I go whatever. Chat Bot with a brain that you have will remember. The conversations you've you've had and what you've done in what you've tried, what you're talking about. and. What equipment you have you know Whether you whether it's been is on the latest version and you know it can do can do tests automated testing because I? Hey. Let me test the line. And you know it. All of that can happen smoothly and efficiently whereas I know we've been working with companies like it and usually these calls service calls take half an hour tech. An hour was a human agent and it's just like super frustrating. resetting go poss- would Ed Bankin it's like Insane of what you have to. What hoops you have to jump through you know.

Amazon Representative Personal Assistant Brian Ed Bankin Chad
Russia, China, Iran having a red hot go at US political organisations

Risky Business

04:10 min | 1 year ago

Russia, China, Iran having a red hot go at US political organisations

"Going to begin with a bit of a a tragedy in media, which is team at Reuters the security team at Reuters, we're onto an absolutely cracking story. That they had to hurry up and publish because they caught wind that Microsoft we're about to ruin their party time But yeah, they had a fantastic exclusive here about Russian efforts to target the. Biden. Campaign. yes. Reuters are reporting attacks against the same Biden. Campaign of this company called A. S., K. K. Knickebocker. who provide services for them they appear to be based on Microsoft's cloud and coming under attack from the Gi you fancy bit crew going up against you know people involved in the political world the Reuters reporting his focused on this particular organization. But Microsoft's the level of visibility across cloud infrastructure does seem to suggest that actually it's a much wider campaign going on for some time against a number of organizations across political spectrum in the US. Yeah. I mean Microsoft really did release a fair bit of information. It looks like at two hundred organizations targeted by Gi you. They also detect I detected a Chinese stipe backed group IPT thirty one. Basically invalidate email addresses and profile targets sort of doing recon work and they squashed a bunch of domains being used by the Iranians. It's. The contrast between now and two thousand sixteen right way. This stuff is absolutely being taken seriously. I've heard some people say, Oh, well, this is evidence that Russia's trying to interfere in the election. It's not I mean that that could be what they're trying to do but we don't really know what they're up to for all. We know they gathering intelligence. Yeah and the reports that we're seeing a marked swift information describes a whole bunch of attempting to gain access. We don't know what access was gained as a result of these attempts and then what it was used for like those kind of obscure to spot the sort of things that Microsoft reporting Eric you know exactly what you would expect. Right Password Password Reuse credential stuffing type things. Fishing all the usual sorts of techniques that as you said in two thousand sixteen. Worked very effectively and now in twenty twenty, twenty, nineteen, you know we are much better equipped that much much better equipped. To be able to those things, and this is one of the advantages of people moving a lot of this stuff into the cloud is we do get this kind of central visibility in a way that we we just went getting when everyone was using. You know you're here and hotmail there now there's a much more concentrated intelligence, available Microsoft and more. Of An understanding of why it's important to talk about the Microsoft price goes for all of the attempts here and how you know how frequently they were doing force attempts against various accounts and whatever, and they said that we using a pool of approximately eleven hundred Ip's the majority associated with the tall and an amazing service which I interpret that to mean. Mean Tour Exit nerds right and of course if you're seeing like. Hundreds of thousands of filed log attempts from tour exit nods you would think maybe that's how they caught this year. That's a little bit of giveaway. You know obviously being able to you know pull of exit cards are and be able to correlate that there's a pretty strong indicator and it's just kinda funny. I guess in a way because you know illustrating the very deal use nature of talk. Yeah, and Microsoft's advice. Here's a little bit confusing because they like here's enlisted five hundred and thirty net blocks that are associated with this activity and I'm like, do you mean for like? Is this the other ones that want? Already knew about. This other we had language in the release about how they separating forcing from poss- would spraying and you can tell like the fact that they've made a distinction between those things is the result of a really intense. Twain. Various people. That's that'd be my guess. But you know it's good that this stuff is being turned up right Yeah absolutely I. It's good. It's being spotted and being communicated, and also the defensive options for people like things like enable factor indication and monitor failed loggins like those are things that you know in twenty six were actually difficult for people and now you modular Microsoft's licensing from for. Know a much more straightforward for people to do, which is I guess an

Microsoft Reuters Biden United States Twain Russia A. S. Poss Eric K. K. Knickebocker.
20 Minutes About Traditional Chinese Medicine

20 Minute Fitness

05:50 min | 2 years ago

20 Minutes About Traditional Chinese Medicine

"Welcome back to twenty minutes fitness. I'm Kessler and you're listening to your favorite podcast for health and fitness science and technology. Today we're airing the second part of my conversation with Dr Marcus Gado, a leading Chinese medicine practitioner from Europe who spend close to a decade in China learning the ancient Art of traditional Chinese medicine also referred to as. If, you haven't listened to last week's part one of our conversation. You May WanNa poss here and listen to it first so that you can learn about his background and what he believes, he can teach us about our own emotional wellbeing and healthy nutrition in today's podcast who we will continue the conversation and cover how. Six to guide how we should exercise sleep and even have sex. Yes. Heard correctly the how and when of sex also plays a role of healthy living in ancient Chinese wisdom. So beware that today's episode is pg rated because of that disclaimer why Chinese medicine has been around for thousands of years? It is really just at the cusp of being scientifically looked at an understood it is usually fascinating topics we. Wanted to share with you, it is hard not medical advice by any means nor endorsement of the scientific validity or efficiency of any of its practices or interventions. Having said that we do try to stick to only the things that have already been backed up by signs, and you can find a full list of studies and Research Without show notes on twenty minute dot fitness. All right. Let's have at it. Or let's move on to to sleep I. Think the third tip is get plenty again seasonal steep was is that mean? Yeah. If you look at animals, they're way more Richard Eight. Some analysts even hibernate in summer and social we we shouldn't be sleeping the same amount of hours throughout the whole year and well, it's good general of funding to get at least eight hours of sleep in the wintertime nine or ten hours is fine and in the summertime if you're feeling really energetic seven or six and a half if you're feeling great is actually not the bad for you and but the Chinese say that. Especially, the early Stephen in modern sleep research confirms this that early steep, sexy, more beneficial because you're getting a lot more autographs wrong excreted in the hours roughly before midnight and so the Chinese advocates between nine thirty and ten thirty, and then of course, old biohacking stuff you know keeping blue light our heading your house of very dim lights getting you really into this calm evening mode and have no ben at a TV and don't eat obviously before you go to directly before you're gonna go to bed and instead off the Chinese medicine advocates to have some green team your cup of tea because it's so. Call me you down activating the Perez pathetic nervous system. It's advocating for a bit of movement no meditation before you go to bed or even even taking a hot foot. That's a great little trick that you can fall asleep or joystick colts he keeps you up take a hot foot and research has shown that down hot foot actually heading the black by heading this hot water your feet. It increases the circulation periphery in your feet which saw in our regulatory process lowers the corporate body temperature, and we'll have a lower temperature it signals to the brain. Time and so these are some little tricks that the Chinese advocates and in another great one is actually funded fool study here Naski and others in two thousand seven they had two hundred thousand subjects in Greece against epidemiology but again, food for thought day found a thirty seven percent reduction in cardiovascular disease of people who regularly had a Siesta who took a little nap at night thing that study was quoted in a wide receiver is really interesting book I that everyone should read yeah. That's the guy from UC Berkeley, Matthew Walker that's right So So yeah a lot of these these things that they that they already figured out and keep the probation is a big one, right Here's another statistics who has National Health Center for statistics in nineteen sixty, two percent of American slept less than six hours while in two thousand four, it was already thirty percent. So generally speaking we're not sleeping enough. So wildly you WanNa just your sleep in obviously the day is longer than summer so you could also stay up a little bit longer but the country in the wintertime you shouldn't feel bad on your cells you need nine or ten hours of sleep a really give your buddy that go with the season skull was the dynamic of nature and let your body hibernate Chinese proverb says no losing a night of sleep as followed by ten days of inconvenience. Never never sacrifice after sacrifice sleep and sleep a little bit more in winter, and then you can stay up longer and have more energy into following summer. Again, let's just quickly touch on the fourth a little hit or tip to stay healthy in twenty twenty I picked this one because I think it's contrary to what we believe in the West and does the about exercise movement excise the Chinese things that moderation here again is key. So we shouldn't be doing chronic cardio over having really high pulse rate on training for ultramarathons but instead we should go on strolls and walks and we should exercise buddy while the do it in short intervals and with a high intensity. High intensity interval training or just even intensity training where we doing body weight exercise in keeping a muscle mass obstacles casino the Muscles Pretty, much ski organ of Longevity. You can draw a line of lean body mass versus fat mass and an pretty much. It's with old people get and it gets difficult at your old to build and maintain muscle story you WANNA regularly. Exercise. Your buddy but you don't WanNa chill your body lacked we like to do in the West aware that where it is even for a lot of people, it ends up being addiction like an exercise addiction but

Dr Marcus Gado Kessler Europe Stephen Richard Eight China Perez Naski Berkeley National Health Center Matthew Walker Greece
EA's Competitive Vision & What Esports Means To Them - With Todd Sitrin

BIG Esports Podcast

04:33 min | 2 years ago

EA's Competitive Vision & What Esports Means To Them - With Todd Sitrin

"So I guess going into that question that we wanted to talk about about what what the game in a sport I feel like in the poss, you know as sports titles became a sports accident. Counter Strike one point six, thirty, two united battlefield to play. None of these guys would develop the style with a sports in mind but I just happened to become that way Judah having certain factors to do with the game I'm interested in learning for me like is there a special formula that that makes game in sport your mind? I would never use the term formula, which makes it seem like. Crying out entertainment and Is Never. That easy. You know I think there's a few wins to look at that question and the heart of it is at to some degree as is what? Beyond just the community thing. Hey, we liked to watch people play. And many communities have done and it sort of built up. The need for I'd say Super Smash Brothers is an example of out where the community basically just rally around. Here's a game that hasn't really been. Updated for a long time and yet the community's still wants to do that. from a publisher point of view. I think you have to ask the question why are you doing any sports in the first place and I think there are two reasons I can tell you why E as the The first is it is a marketing vehicle for the video games right? People see people playing the game they get to know the game they get excited about it. It drives them too many purchase the game or drives them back to engage in the game, and that's you know that is the reason why sports was created and that is actually the reason that the vast majority of the eastwards industry is based on that and that's how they measure their success. So the question is, can you build a big enough? In can you engage a? Viewer to become a player or. As. The case. Were taking we're not really trying to necessarily grow the player base were just trying to get more, engaged our aims and so free to play games that you know have a revenue stream that come from people playing the game more and more. That's where the birth of these all came from. And they're still they're still like that Doda too. I think is bill clearly on that model. But there's a difference of reason also too which I think there are a few of us that are. Publicly saying this is what we wanted to as well, which is to create a media business based upon your show. and. That treating the eastward as a entertainment property unto itself that you can make money from through meteorites, sponsorship, merchandising, etc, and. I think that's much smaller group of companies publishers that are trying to do that. And so when it comes back to your question, which is what's sinise sport I think it kind of gets answered based upon what what's your. What's your goal? For us, we look at it and saved will look at the bare minimum you need a game that. Is Competitive in nature writing and it has to be honestly legally it has to be competitive in nature writes out yet to pass certain governmental rules around what what what is. What it was an actual game competitive game. So that's like bare minimum but clearly we look at things allied engages the community right? Guess Start from zero very few examples were games have started from zero to create east sports normally to gain was already a certain level popularity beforehand. So we're not worded the competitive gaming. Room. The first two games that I went behind was Viva Matt. Why be the biggest one of the biggest games in the world certainly the biggest game? And Man is the biggest game one of the biggest games. North. American sort wait the biggest gain the AD in North America on the sports side, and so that was really based on their competitor. Yes. They have engaged communities and they're they're quite big So you know to me that's the starting

Viva Matt Judah North America Publisher Sinise