7 Burst results for "Polly -ployed"

"polly  ployed" Discussed on The Peter Attia Drive

The Peter Attia Drive

07:56 min | 5 months ago

"polly ployed" Discussed on The Peter Attia Drive

"And so this experiment they went in, and they eliminated Smith and cells in the course of wound healing, and what they saw was at the wound, closed last well, and more slowly, and it suggested that the S- asp had another role wasn't just Sassy. This is April for this ASP here. Its role was to facilitate wound closure, which if you think about it for most organisms in naturally evolving ecosystem, super important, and so essentially senescence got co opted into suppressing tumors in one case. In in a very different case was co opted into helping heal. Won't and so I think that what you see in these diseases of aging is often sort of unintended consequences of a system that was absolutely awesome for the young at the expense of the old one metaphor for this, that I sort of like is that let's say you innocently. Write A computer program to fill your bathtub. It also unintentionally becomes A. Computer Program designed to overflow. Your apartment wasn't why you wrote it, but it is the net effect now. That's an interesting point. Certainly things that favor wound healing could be quite beneficial as some have even argued that LP, little a lie protein apolipoprotein little a which is attached to ldl also makes this thing called little a has very potent pro thromboembolic properties, and even though it's only atherosclerotic, you could argue. Frankly, that's a very. Favorable phenotype to carry for most of our evolution. It's only recently that we need to concern ourselves with Atherosclerosis, but there was certainly an era where having a pro thromboembolic factor to help you in periods of trauma would far outweigh the tail effective knocking off if you elders who managed to survive in Divy Arctic's Raffarin grosses, so that's an interesting tidbit with respect to the wounds stuff I wasn't aware of that by the other. Other example you this appeal as a perfect comparator to the whether or not either of these teleological explanations matters not the point is is that those are the same logic, so let's go back to something you said at the outset, which you've now given US enough to put in context, you said, look you, you sort of you went on this journey of thinking through final common pathways of aging you sort of arrived at. This M tour CR thing probably matters a whole heck of a lot. In fact, it seems to be the only one that works across. Across labs. No, it's answer butts. You've got this loss of circulating youth factors. Clearly, something is happening to might occur Andrea as we age, that is very problematic. We clearly see this observation of methylation whether it's causal or not, as is unclear, we get a sense of what's happening to stem cells, exhausting and Senescence sells your view, which you very briefly touched on is the first four things I mentioned. Are probably harder to drug than the last one. Is that fair summation of how you arrived at this? Yeah, that's how I wound up focusing last eight years of what myself and my colleagues working on was that was. How do we make medicines that target a fundamental mechanisms aging I was not clever, enough or knowledgeable enough. For both. To figure out how to do. 'em Tor and CR. Mean there are a lot of people who are trying that by trying to get more and more selective molecules, but it was not an area where I had anything creative to at, but the Baxter. How I kinda got involved. This was I was sitting around actually in the Calgary airport. Things are happening airports. Okay, for some reason and I was eating French fries, and in this twenty minute interval of French fry consumption, five different people sent me the same pdf and they were subject lines like. Holy Shit you have to read. This is has to be your next company and I opened up the paper and. Right on the front page was a figure showing these two animals siblings, one of which had and sells the other one. These are the mice. You talked about earlier. Yes, this was yawn or this was judy where they collaborating at the time they were collaborating. Judy was not on this particular paper and this paper was not exactly. The same mice described, so it had a very similar the same. Means of Senescence automation, but there is a difference. This is two thousand eleven. These animals. Also contained a mutation where they made less far less of a protein called but one which is an anti phase checkpoint proteins. This is a protein that makes sure that chromosomes lineup on the spindle and sort of like a bit of a schoolmaster in sort of says. Dividing until everything's lined up and if you don't have Bob, are one you just blow right through the checkpoint and you become polly -ployed yawn vendors in my other co founder and long term collaborator. He created this animal thinking this animal was going to get tons of cancer because he was a cancer researcher, so let's just make sure we understand why. That's the case. If Bob are one is there to make sure your spindles lineup. It means that you should not be able to divide until all. All. Your chroma ten is perfectly aligned. Everything is imperfect. Tip Top order in. You're ready to undergo my toast. That's right, so if you take away your master, a lot of faulty division should follow. That's correct, so yawns. Hypothesis is we either attenuate or knockout Bob are one. We should get a lot of cancer. That's right. Okay? What happened? That wasn't what happened. The animals were super poliploid meaning that they wound up with super weird numbers of chromosomes too many too few all that good stuff. The animals aged quickly, so the animals wound up full of senescent cells. Okay, so there's something about become having very wrong numbers of chromosomes. And all of the effects of that that caused the animals to be full of SASS and Sol's and to age very rapidly. have features of aging that were onset very rapidly and die, so it accelerated the speed with which surrendered played, but it didn't change the music. In other words, they didn't die sooner because they got cancer. They just died sooner because they sped up their aging. We don't know the answer to that, so these animals are extremely sick animals so trying to make a larger. Statement I think it's too much to say with an animal like that of the whole record metaphor. What I can say with I think conviction is that? Clearly a whole bunch of things that go along with being old happened very quickly in these animals and these animals die very quickly. They look visibly old for me. It was an experiment that suggested that. was consistent with the notion that the senescence cells were actually driving these features of aging, and what's so cool about this paper and why it caught so many people's attention, even though there was a somewhat earlier paper that yon also did. That for many allowed to draw the same inference, but it just didn't smell like a drug I won't get into that paper today, but what was so compelling with you added Senescent. Cells through this mutation that gave rise to production of less bub are one protein. And then you eliminated those cells or a subset of those cells with this insert into the DNA every cell of that animal and you could ameliorate. A subset of the effects of sells so you didn't get rid of all the SNEDDON south for buttery. Interestingly, the animals don't live longer. NAP particular mutant, because it's so sick when you eliminate the cells. But whole bunch of the features of aging for example there bent spines their. Organ atrophy their cataracts in their eyes. These were all severely blunted when insults were eliminated and when I saw this paper..

Bob judy A. Computer Program US Smith Calgary Atherosclerosis Divy Arctic wounds Andrea Tor Sol researcher co founder
"polly  ployed" Discussed on The Dictionary

The Dictionary

12:59 min | 10 months ago

"polly ployed" Discussed on The Dictionary

"I don't I haven't seen all of it and I don't have it memorized as you probably do but I'm sure it was in there. Oh Yeah we have to call all we eat. That was one of the few exceptions in our family when TV could be on during dinnertime mash was appropriate. Be Apparently Yeah. Yeah well we should call call Alan Alda up and ask him about that okay All right where were we western. Oh and I was GONNA say in the as the word. Nimble is related at Tema logically To autonomous probably because of the word no most law nimble is sort of similar. Anyway we are going to move onto onto autonomy This is a noun from circa sixteen. Twenty three one the quality or state of being self governing especially the right of of self government. Yup You said it was number two self directing freedom and especially moral independence moral and a number number three a self governing state. Anything else you gotta say about autonomy. Okay no we've had a lot of talk about that yet. We go all right next. We have the auto pilot Little airplane movie. Oh Yeah Yeah we're Murray. Let's let's hold onto that. We'll get to that but it quickly I want to say in the last episode With Andrew we had automatic pilot and And the synonym was auto pilot And we said you people just you say autopilot who says automatic pilot anyway So autopilot is a noun from nineteen sixteen won a device for automatically steering ships aircraft and spacecraft. So Elon. Musk and this whole thing is It's not self-driving it's Autopilot goes on autopilot. And can you. Can you tell the story of From that movie airplane what the autopilot joke. Yeah that was the just hit the button. That said autopilot. An inflatable flagel. Rubber man came very cartoony whom he looked. Like one of those things that you punk right right with sand in the bottom that rocks back and forth and he just drove the plane. Plane flew the plane. Excuse me yeah. Awesome if you've never seen the movie Lucy did she have to blow it up with their mouth and the tube was in his fly of his pants and she was blowing him up. Wasn't that it it might have been. We're GONNA WE'RE GONNA move on from right but I think you might be partially right. or he was deflating orange. Inflated that might have been what it was it was And then the number two definition for auto pilot is the number to definition for automatic pilot. Islet which was in the previous episode next. We have auto polly -ployed This is a good one a U. T. O. P. O. L. Y. PL. Oh I D. It is a noun from nine hundred twenty eight an individual or strain. Who's chromosome complement consists of more than two complete? Copies of the genome of a single and sessile species auto. Polyp Loyd is also an adjective and who I like this word. Auto polly is a noun and okay very occupied deployed eighty dope by auto polly. Lloyd don't be so autopart deployed All right next. This is an interesting one. It is the word autopsy This is a noun from sixteen. Seventy eight one an examination of a body after death to determine the cause of death or the character and extent of changes produced by disease and it is called also necropsy or neck. rupp see We'll just finish this up and then we'll talk about it. Number two eight critical examination evaluation or assessment of someone or something gene past autopsy also a transitive verb This is from the Greek autopsy which means act of seeing with one's own eyes and That is actually the name of a documentary. Made by a guy who I think is the first name was stand. Anyway it's basically a documentary of autopsies. Maiden maybe the seventy s or something. I saw part of it in a film class and I had to end up looking away away for most of it It was really hard to watch My wife Sharon would have loved to watch that actually And yeah the the name of the documentaries act of seeing with one's one's own is which is the Greek word autopsy at which And then let's see that is from ought plus Oxus is which means site or appearance and there's more at the word optic So yeah for those who don't know when an autopsy is done They want to figure out the cause of death. They opened the body up and figure out what happened. Why did this body die? This is. I've just been thinking about mummification. Really right now now but that was not an autopsy. Didn't really care why he died. They just wanted to make sure. You've got the underworld might have done autopsies for all we know for all I know at at least I don't know somebody knows but yeah that was mummification. was when somebody died they would take out all the organs and wrap the body and so it was preserved for the afterlife consensually. Let it what is it called when you at the funeral home when they prepare your body right Similar well I I think a lot I was gonNA say some that I didn't want to. I don't know if I can. Yes embalm. So that's when they get rid of all the blood and the body and they replaced it with embalming fluid so the body doesn't Deteriorate right away so you can have an open casket funeral essentially right right. There's no real that blood where does it go. Oh you don't WanNa know I don't want to know I don't know well then I didn't ask okay. I'm sure they do something with it. That is a good question. It's gotTa go somewhere. You should google that the golden blood right wouldn't be surprised. I mean we're made up of lots of different molecules and things so it probably is all right we're going to move onto auto radio Graham This is a noun from nineteen thirty one and we just have these synonym auto radio graph. which is our next word? It is a noun from nineteen nineteen o three an image produced on a photographic film or plate by the radiations from a radioactive substance in an object which is is in close contact with the emulsion Osteo auto radio. Graphic is an adjective auto. Radiography is a Noun X ray. I think it's similar Yes cursor maybe maybe maybe ninety three I don't remember when X. Rays were figured out But but yet they seem to be related. Do you think there's truth to the Tesla x Ray that he was a person who was like. We can do that like he knew about that. Oh Oh you're talking about Nikola Nicholas not the cartels no. I would not be surprised because that guy had so many inventions engines and things that he had discussed or made plans of never created and things that we use today he had a hand in or things that we have now that he actually invented but didn't actually. Yeah so I wouldn't be surprised if he was involved with x Ray. Somehow I don't know why we're still on x Ray. I'm sorry about this but I feel like the guy who was finally. Got The right equipment to do. It was shooting it into everything. And didn't he kill his wife overrated his wife or something like we kept taking pictures of his hand is in his hand. Got All burnt up or something. Yeah I think there was something about that. I think the the only thing that I know in regards to that is that he found xrays by accident right. Yeah they like he had filmed that was exposed to something accidentally And it and it developed into something. And that was the beginning of x-rays but yeah he I think he did something with his hand. I'm sure I'm sure a lot of people were killed in that time period when people were just experimenting like crazy crazy and who knows what they were they were doing but yeah There's probably some truth to that. I always remember being very scared as a child going to the dentist when they put that big. I haven't been to the dentist and year so they probably don't have that big camera level ORLEA. That just comes down to the conical point and they just feel like they're just shooting a direct stream of radiation just into my mouth like they used to bite down on the. Oh the because that's like the film I don't know if they you use actual film anymore but yeah that's the thing that needs to get exposed. Oh but it feels so good when they shoot you with those xrays. A Dude I quit going to the desk because of that office. It's I mean it's a very low amount of radiation. It's you're exposed to it a little bit you you get more radiation like in a plane maybe or something like data than It might be part of that I think just in the I don't know I don't know the details. But you're exposed to radiation all the time and it's it's it's minimal but the people who work there who are exposed to it. Yeah they damn well right because because they're exposed to it so often when you go once twice a year. Yeah it's not that much right but maybe some people are more sensitive to it All right we're getting near the end of this episode. People were very close. Auto rotation is next. It is a noun from nineteen twenty six the turning of the rotor of an auto gyro or a helicopter with the resulting lift caused Solely by the Aero dynamic forces induced by motion of the rotor along its flight path auto rotate is a in-in-in-in transitive verb verb and I think it was in the episode with Ryan. Two episodes ago we had the word Auto Gyro So that which is basically a helicopter a love helicopters. I really want to go in a helicopter ride when Sharon and I were in New Zealand We had the opportunity It's a long story. We get getty we could eat. Choose either to fly in a little small little plane to get back to our hotel quickly or in a helicopter because we didn't want to sit in the like eight hour bus. That's right again We want it. We should have chosen the helicopter. It was a lot more expensive so we chose the plane which was still amazing? Okay but the helicopter L. A.. Copter would have been cool because then they would have landed us glacier and we could like look at the views and we've been awesome all almost any time. The helicopter is an option. And take afford it right. Yeah because we were in Saint Lucia. You're still yet. And I were in Saint Lucia and then they did the same thing they like. Oh do you want like they scare the crap out of you drive in you from the airport to the resort which in tiny little plane. Yeah driving you know driving you and that's and it's like right it feels like you're GonNa there's cliffs lifts and you feel like you're just it's dead bill. You're just doomed right. And then they get they get you there and they're like hey you wanNA drive backers. Can we take you on a helicopter. And then the idea of being flung through the the air seems less intimidating than having to drive back on the ground. It's a weird but anyway it's beautiful up there so you did take the helicopter we took because it was It was was late in the off season and like somebody had they offered some special. You know how the Internet is they say. Hey we have these things and then you pay. I hardly any money and you get there and so we were like well. We'll just eat that up by taking the helicopter ride here. Yeah I mean yeah if it's cheaper than do it yeah all right right next as auto rally for everything. If it's cheap do it just do just do it. It doesn't matter what it is as long as it's not expensive. Just do it even. If you don't like it the okay auto route or autoroute is next It is a noun from nineteen fifty one and expressway away especially in France so I guess there Most of their expressways in France or called auto routes or auto routes It was interesting. That Lecarr was. It's not called the LA auto if we're GONNA so much French connection between auto car remember liquor are no. You don't remember those things. They were so cute at a French card. It's like the Renault of its time. Yeah it was a French car from when before my time who well stare at a plane dungeons and dragons and second grade so I remember that the guy who owned the Comic Book Fantasy Dungeons and dragons store had the car was parked in the Strip mall so it had to be around that time period so that was actually a French car. Lecarr look on the car. Seems like they didn't try to heart racing stripes and went down and then they'll racing stripes. I Feel Inc.. Let car Yeah Yeah Yeah Right. They were tiny. I'm not a car guy so I don't know about wasn't I should look up a picture next we have autos defray hey I think we had a similar one day..

Ray Sharon Alan Alda France Murray Saint Lucia Elon google LA Polyp Loyd Tesla I Feel Inc Strip mall Lucy rupp Andrew Musk Lloyd Lecarr
"polly  ployed" Discussed on The Dictionary

The Dictionary

10:12 min | 1 year ago

"polly ployed" Discussed on The Dictionary

"Hello word nerds. First word for two day is allocution. A. L. L. O. C. U. T. I. O N. This is a noun from sixteen fifteen a formal speech, especially an authoritative or, or a Tory address. The etymology says this is Latin ala Kyo, or Allah, que-, which means to speak to, and that is from ad plus low Kwee, which means to speak next is all of two separate words. This is an adverb from eighteen twenty nine. We have the synonym fully F U L L Y as in. She's all of twenty years old next is a log. Humous. A. L. L. O. G. A. M. O U S. This is an adjective from circa, eighteen ninety reproducing. Ng by cross fertilization, Alaga Amee is a noun next. We have allo generic. A. L. L. O G, E, N E, I see could also be allergenic, which is what I thought the word was in the first place. This is a an adjective from nineteen sixty one involving derived from, or being individuals of the same species that are sufficiently. Unlike genetically to interact anti genetically, as in ELO generic skin graphs, and it says compared to the word sin generic, which I assume is the opposite next. We have. Allographs. L. O. G. R. A F T. This is a noun from nineteen sixty one, a homo graft between allergenic individuals allographs graft can also be a verb. Now. We have allo graph. G R. A H not. G. R. A. F T. This is a noun from nineteen fifty one one a letter of an alphabet in a particular shape, as capital, A, or lower case a to a letter or combination of letters that is one of several ways of representing one phonemes as p p in hopping representing the phone, name p aloe graphic is an adjective. So I guess what it's saying is, basically, the shape of a letter is called an aloe graph. Learn something new every day. Especially when you read the dictionary next, we have Allama tree. A. L. L. O. M. E. T R Y. This is a noun from nineteen thirty six relative growth of a part in relation to an entire organism or to a standard. Also, the measure and stuff. The of such growth, aloe metric is an adjective, next. We have allo. Morph. A. L. L. O. M O, R, P H. This is a noun from nineteen Forty-five one of a set of forms that a more fem- may take in different contexts as in the s of cats, the E N of oxen, and these zero suffix of sheep are alum morphs of the English plural morphine. So I think what this is saying is that there's a thing called the plural morphine, which is the thing that exists to make a word plural. So the s in cats, the E N in oxen and nothing to the word sheep. And so those are called, although morphs aloe more Fiqh is an adjective, and ELO morphism is a noun I think I would have. To learn what other morphines are to find out what aloe morphs are, but I have a little bit more of knowledge of that now, which I probably won't remember next. We have alone j- I think that's how it's pronounced A L L O N G E the pronunciation guide is one of the stranger ones I've seen. It's got an A dash apostrophe L O with the the line over it to say that it's a long. Oh. Then there's an N A super script end. So it's small and it's up top. And then a Z h don't worry, I won't keep on describing the pronunciation guides. This is a noun from circa eighteen fifty nine. We just have the synonym writer to a and writer is spelled R, I, D R. The etymology says this is French and it literally means. Lengthening. So if I were to say this with a French accent, I would say at horribly, but it would be something sort of, like alone JR. But somebody who knows French would say, it much better than me. Next is. Allopathic. A. L. L. O. P. A T H. See this is an adjective from eighteen thirty relating to or being a system of medicine that aims to combat disease by using remedies as drugs or surgery, which produce affects that are different from or incompatible with those of the disease being treated next. Is Allah, Patrick. A. L. L. O. P A, T R. I see. This is an adjective from nineteen forty two occurring in different geographical areas, or in isolation as in Allah, Patrick spec-, Asian, it says compared to the word sim, Patrick. And that is not the first time we've seen that the opposite of one of these aloe words has an S Y at the beginning, aloe. Patrick Lee is an adverb an aloe Patrie is a noun. The etymology says this is made combining all, plus the Greek Padro, which means fatherland, and that is from Potter, which means father, and there's more at the word father next is Ella Fain, the end of it is P. H. A N E. This is a noun from circa eighteen twenty one and a morpheus translucent mineral of various colors often occurring in, in crustaceans, or stalactites forms and consisting of a hydrogen aluminum. Silicate the etymology says this is from the Greek allo fannies, which means appearing, otherwise, and that is from all plus finest sty. By P, H, A, I N, E, S, T, H, A, I, which means to appear, and that is the middle voice of finding which means to show and there's more at the word fancy next. We have. Elephone. P. H. O N E. This is a noun from nineteen thirty eight one or two or more variants of the same phone name as in the aspirated p of pin, and the Annaspiratou p of spin are Allophones of the same phone name p I'm not one hundred percent. Sure on what they mean by aspirated and Annaspiratou, but I might have to look that up. But here we've got another aloe word that is related to letters in sounds in such Allah phone, and Ella morph, Allah phonic is an adjective next is. Allo polly. -ployed. A. L. L. O. P. O. L. Y P, L O, I D, this is a noun from nineteen twenty eight. It's a great word a poly -ployed individual or strain having a chromosome set. Composed of two or more chromosome sets derived more or less complete from different species aloe polyp Loyd is also an adjective and aloe Polly ploy. D is a noun. Whoa, aloe. Polly, try and say that ten times fast next is Allah, pure and all a. L. L. O. P. U R, I N O L. This is a noun from nineteen sixty four eight drug c five h four and four oh, used to promote excretion of uric acid next. We have the phrase all or none. It is hyphenated. This is an adjective from one thousand nine hundred MU. Worked either by entire or complete operation or affect or by none at all as in all or none response of a nerve cell next and last four. This episode is the phrase all or nothing. It is hyphenated. This is an adjective from seventeen sixty five one just has the synonym all or none, which is what we just read to a accepting, no less than everything as in. He's an all or nothing perfectionist. I Kana used to be that type of perfectionist, but I've chosen not to be in my old, age and to be risking everything as in an all or nothing combat strategy that will be the end of this episode. Thank you very much for listening, go ahead and share and rate, and review and tweet me. And Facebook, me and Instagram. No, I don't have an Instagram, and calm, Google voice and until next time this is Spencer reading the entire dictionary. Thank you. And goodbye..

aloe Polly A. L. L. O. M O Ella Fain P. H. O A. L. L. O. morphine Patrick writer A. L. L. O. C. U. T. Alaga Amee A. L. L. O. G. A. M. Allama tree A. L. L. O. M. E. T Facebook Patrick spec Patrick Lee A. L. L. L. O. G. G. R. A. F
"polly  ployed" Discussed on The Skeptics' Guide to the Universe

The Skeptics' Guide to the Universe

04:14 min | 1 year ago

"polly ployed" Discussed on The Skeptics' Guide to the Universe

"Point five megabytes of data. Now, like text data one point five where we just talking the words everything they need to learn to learn their primary language L interesting. Yeah. 'cause pressed text data. I just think we almost always vastly underestimate the amount of work that our brain has to do whether it's people saying that we only use ten percent of our brains or only this one areas responsible for for things. So I'm just going to say, this one's on fiction on the on the fact that our brains are awesome. And it's probably many many more megabytes. Okay. Jay. All right. The water fli. Daphna is that how you pronounce Steve staff Neha? It turns out that this has the most genes of any Anwar two hundred fifteen thousand so two hundred and fifteen thousand what genes as it says right in the items. All right. So the two hundred fifteen thousand all right? Let me just move on. Because I something doesn't feel right about that to me. But let me just keep going down to five Quinn trillion. Bits of data are created on the internet every day two point five two point five exit bites day. Thank you. I think everyone zurve that. All right. So two point five x bites. I mean, sure I actually don't think anything's wrong with that. I think I always wonder like how do these companies like how does Google keep up with an Amazon web services? Like, how do they keep up with the increase in need for storage? They must be creating new data centers all the time. Then improving the ones that they have a non stop race this last one here in order to learn their primary language by age eighteen kids store, the equivalent of one point five megabits of data megabytes megabytes megabytes that doesn't seem like a lot to me the the two that have to deal with things that I am familiar with the two point five billion and the one point five megabits those things don't bother me at all. It's the first one bothers me there's something not right about this one this hold this thing about the water fleas and the six legs and all these pairs of jeans. I don't agree. I don't like this guy's probably buying lots of pants and then just throwing them away. So the water flea you're saying the fiction fiction. Yes. All right CARA. Right. So eric. Could you have more Malays in your voice, please this is hard? Okay. So J went with the water flea Tyler went with a one point five mega bites of data for kids. But that's only based on how many how much data they need to learn their primary language by eighteen don't kids already know their primary language by eighteen fully fluent, and they have an eighteen year olds understanding of their language. Yeah. God, okay. See the only one that. I know anything about would be the water flea one. Because like you said at the very beginning. Steve this is going to be one of those ones where you could be off by an order of magnitude, and I would have no idea like two point five Quinton bytes of data is a meaningless number to me. That's just lots and even one point five megabytes of data is I mean, it's not that many. It's smaller we at least operate in the Kila mega Giga world. Right. Because we use compute. Tres? But I still don't really understand how computers process my data. And like what I kinda generally know how big a picture is. But a photo has a lot going on with it. And I think that you made a good point Tyler with text data language could all be text data. I don't know that one's really confusing. I feel like it just doesn't have enough information. But when it comes to a flea a flea animal. I'm pretty sure that animals are all diploid. So you don't get this weird. Polly -ployed, he stuff like you get with plants. And I'm under the impression that like all animals are in the tens of thousands of Rangers. I've never heard of any animal even having more than like fifty thousand genes, even that seems high to me how many people have like twenty something thousand thirty something..

Anwar Tyler Steve Google Rangers Polly -ployed Jay Daphna eric five megabytes five megabits eighteen year ten percent
"polly  ployed" Discussed on 60-Second Science

60-Second Science

02:46 min | 1 year ago

"polly ployed" Discussed on 60-Second Science

"This is science Americans. Sixty seconds science. I'm Christopher Dodd yada. It sounds like a witch's recipe gathered the hearts of offense lizard, a Little Brown bat and naked tailed Armadillo and dozens of others we try to get them from zoo. But I'll fortunate we the student walkout very well. We couldn't get any samples even when dynamo die could get heart developmental biologist at the university of California, San Francisco, he says they had more success obtaining specimens from the jars of natural history, museums, but the reason for this biological scavenger hunt Wong and his colleagues wanted to examine the number of chromosomes contained in heart cells across the animal kingdom, because there's a curious phenomenon in our hearts, which is that most of the human body cells are diploid, meaning two sets of chromosomes one from each parent, but the lion's share of our heart cells are actually Polly -ployed, meaning two or more copies for mom two or more copies from dad. What one and his team found looking at that collection of hearts is that the proportion of Polly played cells in a heart goes up as you go from fish to lizards to him fibia NHS to transitional species like platypuses to mammals, the reason that finding might matter to us is that recent studies in mice, and zebra fish of shown that hearts with more diploid cells, like zebra, fishes are actually able to regenerate and heal themselves. Hearts with more. Polly -ployed sells like mice and humans cannot. So what makes a heart have more Polly played cells and thus less chance of regenerating costume. Oh costume. But one answer once team found is that thyroid hormone, the same hormone that regulates metabolism and makes us warm blooded creatures might be to blame. Because when they added extra thyroid hormone disease officials tanks. They're tiny hearts were no longer able to regenerate. And conversely when they engineered mice to have hearts that were insensitive to thyroid hormone, the mouse hearts could regenerate back after injury heart function, which is mainly measure contracted the of the heart. We can see to heart function improve or would tie off the injury. Welcome to my cannot improve. The results are in the journal science as for fixing human hearts, perhaps manipulating thyroid hormone levels could be a start. We know regularly in federal home alone, not sufficient to cure, heart disease. Lisa for promote a har-, Richard. And completely. And if we can figure out other major regulator of this process, we might be in a. Better shape. Thanks for listening for scientific American sixty seconds science. I'm Christopher Don. Yata?

Polly -ployed Christopher Dodd Christopher Don San Francisco university of California NHS Wong Lisa Richard Sixty seconds sixty seconds
Effects of Thyroid Hormone on Cardiac Function

60-Second Science

02:29 min | 1 year ago

Effects of Thyroid Hormone on Cardiac Function

"Gathered the hearts of offense lizard, a Little Brown bat and naked tailed Armadillo and dozens of others we try to get them from zoo. But I'll fortunate we the student walkout very well. We couldn't get any samples even when dynamo die could get heart developmental biologist at the university of California, San Francisco, he says they had more success obtaining specimens from the jars of natural history, museums, but the reason for this biological scavenger hunt Wong and his colleagues wanted to examine the number of chromosomes contained in heart cells across the animal kingdom, because there's a curious phenomenon in our hearts, which is that most of the human body cells are diploid, meaning two sets of chromosomes one from each parent, but the lion's share of our heart cells are actually Polly -ployed, meaning two or more copies for mom two or more copies from dad. What one and his team found looking at that collection of hearts is that the proportion of Polly played cells in a heart goes up as you go from fish to lizards to him fibia NHS to transitional species like platypuses to mammals, the reason that finding might matter to us is that recent studies in mice, and zebra fish of shown that hearts with more diploid cells, like zebra, fishes are actually able to regenerate and heal themselves. Hearts with more. Polly -ployed sells like mice and humans cannot. So what makes a heart have more Polly played cells and thus less chance of regenerating costume. Oh costume. But one answer once team found is that thyroid hormone, the same hormone that regulates metabolism and makes us warm blooded creatures might be to blame. Because when they added extra thyroid hormone disease officials tanks. They're tiny hearts were no longer able to regenerate. And conversely when they engineered mice to have hearts that were insensitive to thyroid hormone, the mouse hearts could regenerate back after injury heart function, which is mainly measure contracted the of the heart. We can see to heart function improve or would tie off the injury. Welcome to my cannot improve. The results are in the journal science as for fixing human hearts, perhaps manipulating thyroid hormone levels could be a start. We know regularly in federal home alone, not sufficient to cure, heart disease. Lisa for promote a har-, Richard. And completely. And if we can figure out other major regulator of this process, we might be in a. Better shape.

Polly -Ployed San Francisco NHS Wong University Of California Lisa Richard
Warm-Blooded Animals Lost Ability to Heal the Heart

60-Second Science

02:45 min | 1 year ago

Warm-Blooded Animals Lost Ability to Heal the Heart

"This is science Americans. Sixty seconds science. I'm Christopher Dodd yada. It sounds like a witch's recipe gathered the hearts of offense lizard, a Little Brown bat and naked tailed Armadillo and dozens of others we try to get them from zoo. But I'll fortunate we the student walkout very well. We couldn't get any samples even when dynamo die could get heart developmental biologist at the university of California, San Francisco, he says they had more success obtaining specimens from the jars of natural history, museums, but the reason for this biological scavenger hunt Wong and his colleagues wanted to examine the number of chromosomes contained in heart cells across the animal kingdom, because there's a curious phenomenon in our hearts, which is that most of the human body cells are diploid, meaning two sets of chromosomes one from each parent, but the lion's share of our heart cells are actually Polly -ployed, meaning two or more copies for mom two or more copies from dad. What one and his team found looking at that collection of hearts is that the proportion of Polly played cells in a heart goes up as you go from fish to lizards to him fibia NHS to transitional species like platypuses to mammals, the reason that finding might matter to us is that recent studies in mice, and zebra fish of shown that hearts with more diploid cells, like zebra, fishes are actually able to regenerate and heal themselves. Hearts with more. Polly -ployed sells like mice and humans cannot. So what makes a heart have more Polly played cells and thus less chance of regenerating costume. Oh costume. But one answer once team found is that thyroid hormone, the same hormone that regulates metabolism and makes us warm blooded creatures might be to blame. Because when they added extra thyroid hormone disease officials tanks. They're tiny hearts were no longer able to regenerate. And conversely when they engineered mice to have hearts that were insensitive to thyroid hormone, the mouse hearts could regenerate back after injury heart function, which is mainly measure contracted the of the heart. We can see to heart function improve or would tie off the injury. Welcome to my cannot improve. The results are in the journal science as for fixing human hearts, perhaps manipulating thyroid hormone levels could be a start. We know regularly in federal home alone, not sufficient to cure, heart disease. Lisa for promote a har-, Richard. And completely. And if we can figure out other major regulator of this process, we might be in a. Better shape. Thanks for listening for scientific American sixty seconds science. I'm Christopher Don. Yata?

Polly -Ployed Christopher Dodd Christopher Don San Francisco University Of California NHS Wong Lisa Richard Sixty Seconds