35 Burst results for "Parkinson's Disease"
AP News Radio
Comedian Richard Lewis reveals he has Parkinson’s disease
"Comedian Richard Lewis says he has Parkinson's disease. On marches are a letter with the latest. Richard Lewis says in an online video, he's had a rocky time for the past three and a half years. One reason is because he's been diagnosed with Parkinson's disease, which he discovered because he was shuffling when he walked. Lewis, who is 75, says he also has had shoulder and hip replacement surgeries and back pain. He is retiring from stand up comedy and will focus on writing and acting.
AP News Radio
Virginia Rep. Jennifer Wexton reveals Parkinson's diagnosis
"Of Virginia congresswoman reveals she's been diagnosed with Parkinson's disease, representative Jennifer wexton, a third term U.S. congresswoman representing Northern Virginia, posted a video today, saying she's been diagnosed with Parkinson's disease. If there's one thing a Democrats and Republicans can agree on is that Parkinson's disease sucks. The congresswoman talked about the disease's effects and her plans to continue her work in Congress. Over the past few months, it has primarily affected my speech at how my mouth moves. As I speak more quickly now, has also affected how I walk and keep my balance. Western drew national attention in 2018 when she defeated two term Republican, Barbara comstock, the first Democrat to win the seat since 1978. To be a voice for those struggling with Parkinson's, helping greater resources to the search for a cure. Jennifer King, Washington
AP News Radio
Ozzy Osbourne is retiring from touring, saying he's "not physically capable"
"Musician Asia Osborne is canceling his European tour because of a lingering injury and it may be the end of touring for him. I'm marching a letter with the latest. As he Osborne says damage he did to his spine in an accident four years ago will prevent him from touring because he can not deal with the travel. Osbourne says even with three operations stem cell treatments, physical therapy and a robotic exoskeleton to help with movement, he's not physically capable. He was also diagnosed with Parkinson's disease in 2020,
AP News Radio
Jeff Cook, Alabama Co-Founder and Guitarist, Dead at 73
"Guitarist Jeff cook of the country band Alabama has died after a battle with Parkinson's disease at his home in Destin Florida according to a band representative He was 73 I'm Archie's are a letter with a look at his career Jeff cook joined his cousin's Randy Owen and teddy gentry to form a band when they were still in high school in the state of Alabama with drummer Mark herndon they became the top country band ever Alabama's hits included feel so right love in the first degree mountain music and dozens of others They won piles of awards toured the world and in spite of all that success cook said in a 1996 AP interview there was one aspect of the business he hated I hate the video Well
AP News Radio
Johnny Isakson, former Georgia Republican U.S. senator, dies
"Former former Georgia Georgia GOP GOP senator senator Johnny Johnny Isaacson Isaacson has has died died at at the the age age of of seventy seventy six six Johnny Johnny Isaacson Isaacson an an affable affable Georgia Georgia Republican Republican politician politician who who rose rose from from the the ranks ranks of of the the state state legislature legislature to to become become a a U. U. S. S. senator senator has has died died the the passing passing was was confirmed confirmed in in a a news news release release from from Georgia Georgia governor governor Brian Brian Kemp's Kemp's office office in in twenty twenty fifteen fifteen Isaacson Isaacson disclosed disclosed that that he he had had been been diagnosed diagnosed with with Parkinson's Parkinson's disease disease he he remains remains in in office office until until the the end end of of twenty twenty nineteen nineteen retiring retiring two two years years before before the the end end of of his his term term in in the the Senate Senate Isaacson Isaacson was was known known as as an an effective effective behind behind the the scenes scenes consensus consensus builder builder his his own own views views on on flashpoint flashpoint issues issues such such as as abortion abortion became became more more conservative conservative over over the the years years as as George's George's own own politics politics shifted shifted from from blue blue to to red red I'm I'm surely surely after after
DNA Today
"parkinson disease" Discussed on DNA Today
"Dot org dot com or sorry, Parkinson dot org. Or is there a different website for them to visit? No, they can go straight to Parkinson's dot org slash PD generation. And at that site, they can begin the process to learn more about the study. There's a video, which is required as part of the consent to watch, so give them a little background about genetics and Parkinson's disease and go from there. We're also looking to expand access to broader number of people. So individuals who go see a movement disorder neurologists at centers of excellence for Parkinson's foundation or other neurologists who really take care of a lot of people with Parkinson's disease. We're trying to reach out to them so that they can refer directly to the foundation as part of the process. We've got a lot of interest in this. And that's fantastic. We're a small foundation that's doing our best. And so as we get more support, we can open up more opportunities to do this. But as we've said, it's genetic testing is expensive. And we are paying less because we committed to 15,000. From our provider, but that's not something that's really easily done for most people and or even for the foundation. So we're hopeful that as we accumulate this data coming through, it's researchers like doctor mata here and his colleagues can really hopefully make a lot of it. As well as the opportunity to educate people with Parkinson's, what might be the cause of their disease. And what we're also talking about is that there's clinical trials, which we hope will be coming soon. And that's going to be a key inclusion criteria. Ken, can I participate in this trial? Do I have a genetic form of Parkinson's disease yes? And that's going to be helpful because there's no way we're going to make advances in trying to solve PD unless people are willing to participate in clinical trials. And no one's half the.
DNA Today
"parkinson disease" Discussed on DNA Today
"So picture PD aware is for anyone who wants to access their genetic risk for developing Parkinson's disease. To be the most prepared for your future. Backed by pictures parent lab, full gen genetics, picture PD aware provides clinical reports with genetic counseling support. So you're fully supported and educated about what the results mean for you and your family. Plus, 50% of all proceeds from the BD aware test go to the Parkinson's foundation. A nonprofit organization committed to making life better for people with Parkinson's disease. Visit picture genetics dot com and use code DNA today for 25% off and free shipping. Again, that's picture genetics dot com with code DNA today for your picture PD aware kit, get actual genetic insights today to benefit your family of tomorrow. Unfortunately, there's an underrepresentation of people of non European descent in genetic studies. We've explored this in multiple episodes of DNA today a lulia is also very aware of this issue and how polygenic risk scores develop for people who are of European descent can not be applied to other ancestries without further validations. To directly address this, aulica developed new models to improve predictive power in non European people. Validated their polygenic risk scores.
DNA Today
"parkinson disease" Discussed on DNA Today
"So they'll select those individuals that they think that they have a higher risk to have a genetic form, which is usually derived by family history or if you have very early H of onset. So those are usually the two things that if a clinician see a patient like this will say, we should get genetic testing and see what happens. The PD generation what it's doing is that anybody can come. If they have the disease. So we have a better view of what the percentage is that individuals that might have a genetic cause of the disease, yeah, because before we couldn't really tell. Yeah, and I think that's a really good point, Nacho brings up. So we have really limited inclusion criteria for this effort. I mean, you have to have a diagnosis of Parkinson's. You generally have to be above the age of 18. And that's about it. I mean, people who have cognitive issues. We have ways of working around that. But the basic finding here is that anyone can go get the genetic testing to see whether they have a genetic link for their Parkinson's disease. And when you talk to the clinicians who because genetic testing has been prohibitively expensive, it's not covered by insurance. That's a key thing to mention for at least for Parkinson's disease because of their age and inability to influence care. Insurance companies don't pay for it. And then you can appreciate this to Kira is that Medicare doesn't cover genetic counseling because older people they need it. Yeah, not yet. So the foundation is working to help advocate to get that change because it's so important to have the counseling. Not just the results because it's been a long time since people have had biology in high school and biology in high school probably a lot different back then than it is now. So they may not really appreciate the totality of the results. But when I talk to clinicians, they are saying the people who they think, oh, I'm sure they have got a genetic form of Parkinson's disease. They come back negative. And they're surprised by the people who do have a genetic form of Parkinson's disease. And so as a result, we've talked about the 7 genes that it's in PD gene. As you go down the panel, they get exceedingly rare. But we found somebody who has a mutation in each of those genes. So there's a representative for each of those genes. In fact, one of the rarest forms we thought was going to be someone with an alpha synuclein duplication. We've identified 8 individuals. Who have that? So it's when you have three copies of the gene versus just two. And it's just remarkable what's out there. So this isn't a true epidemiology study where we randomly sample people. But I think with large numbers, we can really get a true sense as Nacho said of what is genetics and Parkinson's..
DNA Today
"parkinson disease" Discussed on DNA Today
"So I thought we could begin the conversation talking about how Parkinson's disease affects the body. Just to lay the foundation so that then we can talk about all the genetics that we know of so far for Parkinson's disease. Doctor Beck, do you want to start out with just explaining how Parkinson's disease affects the body? Yeah, absolutely. So for most people, Parkinson's disease will appear as difficulty in movement. Parkinson's disease is a neurologic disease. It's a progressive degenerative disease of the brain. Primarily affecting movement. So as I said, people may have some difficulty walking, they'll experience some stiffness. Interestingly, a lot of people present because they have sore shoulders. Again, because the muscle stiffness and we'll complain of that as part of that process. But the people with PD experience, what's called bradykinesia, slowness of movement. They will have sometimes a tremor in one hand as it presents. And this is a slow moving tremor that disappears when they move their hand. They may have some trouble with balance and posture. And some other issues with the stiffness rigidity that may accompany it. But most people who develop Parkinson's are in their mid 60s. Maybe a little later for that. But as we'll discuss today, there's some individuals who have genetic forms of Parkinson's disease, which is relatively rare cause of the disease. Who maybe even younger than 40 developed Parkinson's disease. But by and large, people with PD developed the disease for reasons we don't know. And that's part of the efforts behind PDG and certainly behind doctor mata's work to really understand the full genetic scope of what is behind Parkinson's disease. So let's dive into that. What do we know right now, doctor mata about the genes that do play a role in Parkinson's disease? Is there a list so far of what we've identified? Yeah. I think is a growing list. So it never stops every time I go give talks. I always have to keep updating the table, which is good. I was the genetics cause of Parkinson's. It's relatively new. I would say maybe 20 years or so. It was first believed to be mostly environmental..
DNA Today
"parkinson disease" Discussed on DNA Today
"How is it that we find ourselves surrounded by such complexity? Such elements. The genes of you and me Jesus of you and you're all made of DNA we're all made of the same chemical being we're all made of being a man hello you're listening to DNA today, a genetics podcast and radio show. I'm your host keir dunin. I'm a certified genetic counselor practicing in the prenatal space. On the show we explore genetic topics and impact on our health through conversations with leaders in genetics. These are experts like fellow genetic counselors, researchers, doctors, and patient advocates. And this episode we are exploring Parkinson's disease. I'm joined by doctor James Beck, chief, scientific officer at Parkinson's foundation, and doctor Ignacio mata member of the Parkinson's foundation, Hispanic Parkinson's advisory council, and an assistant Professor of molecular medicine at the Cleveland clinic Lerner college of medicine. So thank you both so much for coming on the show when diving into Parkinson's disease with me. Pleasure to be here. Thanks. Thank you. Did you know genetic changes account.
AP News Radio
Jesse Jackson hospitalized after fall at Howard University
"Civil rights leader Reverend Jesse Jackson has been hospitalized in the nation's capital after a fall I Norman hall a spokesman says the Reverend Jackson who's eighty years old was entering a building on the Howard University campus when he fell and hit his head he was taken to the schools hospital located nearby he had joined students protesting the living conditions Jackson instead of undergoing several exams including a CT scan which came back normal Jackson who has Parkinson's disease has already been hospitalized twice this year including treatment for break through covert nineteen infection is Parkinson's has affected his ability to walk and talk despite the setbacks Jackson has resumed an active traveling public speaking schedule I Norman hall
AP News Radio
Michael J. Fox to receive honorary AARP Purpose Prize Award
"D. A. A. R. P. will give an honorary award to actor Michael J. fox for his work with Parkinson's disease I marches are a letter with the latest Michael J. fox will receive the honorary AARP purpose prize award during a virtual ceremony on December fifteenth fox was diagnosed with Parkinson's disease in nineteen ninety one and founded the Michael J. fox foundation for Parkinson's research in two thousand the organization has funded more than one billion dollars in programs for Parkinson's research the
4D: Deep Dive into Degenerative Diseases - ANPT
"parkinson disease" Discussed on 4D: Deep Dive into Degenerative Diseases - ANPT
"Well you know maybe that passive means might take place more. You might see that more kind of moving beyond the neighborhood. So we're like okay. Maybe if we are looking kind of a little bit deeper and breaking apart this like total life space nobility into different components you know at the neighborhood level Maybe we'll see you know. Maybe there's something there and we ended up. Finding that daily. Walking activity was a significant contributor to mobility within the neighborhood limits so in this level one two three some score that we basically created but not beyond the neighborhood not with total lie space and then even breaking that down further. We wanted to see the difference in if there was a difference in sedentary versus active individuals. And we're finding that only at that one two three someday sort that level one. Two three some scored. There was that kind of significant difference in their mobility and particularly their disproportionate. reduction in In the total scored in the score there at the level three which would be the neighborhood level. Okay so we're going to break that down a little bit more a little slower. I think for our listeners so If i'm understanding correctly in the older population the research. That's been done today right. There is a correlation between this total score and the amount of walking that they do but in in your participants with parkinson disease. You did not see that. So total store score did not correlate to their amount of walking right okay and so and in particular that beyond the neighborhood really because we could theorize if you are getting a car to move beyond their neighborhood or some other form of motorized transportation all right so so but then when we look just more locally at how. They're moving within their immediate area of their home slash neighborhood You saw a correlation between how they're how much they're walking and what they report for mobility within the smaller region so sedentary people they were probably reporting more activity outside of their neighborhood and then less sorta daily activity within their neighborhood. Would that be fair to say. Yeah yeah so. We were seeing basically between active and sedentary groups more equivalent mobility when it was kind of beyond the neighborhood so into town and beyond the town I think the sedentary was still a little bit less but it was more equivalent with third reported mobility. Okay and so for your active group when you guys broke those down even further right. You found that really levels one in three. We're kind of more indicative of people's Walking behavior level to cracked. Yeah those were. The two were rehearsing more significant difference between the two groups. I'm the biggest. The largest difference was at that level three so at that neighborhood level. Yeah which kinda makes sense. But i was a little surprised to see that level to seems like it didn't have as much of an impact between the groups and do you have any theories as to why that might be. Yeah honestly. it's surprising not to see that in between level because when we're thinking about you know you have the difference between the inside the home and you know in the neighborhood and then you're not seeing it As much immediately outside the home do you think it's where these people live. So both of these centers are people are coming to our fairly urban people living in an urban setting or maybe suburban where they'll.
Academy of Neurologic Physical Therapy Podcast
"parkinson disease" Discussed on Academy of Neurologic Physical Therapy Podcast
"Well you know maybe that passive means might take place more. You might see that more kind of moving beyond the neighborhood. So we're like okay. Maybe if we are looking kind of a little bit deeper and breaking apart this like total life space nobility into different components at the neighborhood level Maybe we'll see you know maybe there's something there and we ended up. Finding that daily. Walking activity was a significant contributor to mobility within the neighborhood limits so in this level one two three some score that we basically created but not beyond the neighborhood not with total lie space and then even breaking that down further. We wanted to see the difference in if there was a difference in sedentary versus active individuals. And we're finding that only at that one two three someday sort that level one. Two three some scored. There was that kind of significant difference in their mobility and particularly their disproportionate. reduction in In the total scored in the score there at the level three which would be the neighborhood level. Okay so we're going to break that down a little bit more a little slower. I think for our listeners so If i'm understanding correctly in the older population the research. That's been done today right. There is a correlation between this total score and the amount of walking that they do but in in your participants with parkinson disease. You did not see that. So total store score did not correlate to their amount of walking right okay and so and in particular that beyond the neighborhood really because we could theorize if you are getting a car to move beyond their neighborhood or some other form of motorized transportation all right so so but then when we look just more locally at how. They're moving within their immediate area of their home slash neighborhood You saw a correlation between how they're how much they're walking and what they report for mobility within the smaller region so sedentary people they were probably reporting more activity outside of their neighborhood and then less sorta daily activity within their neighborhood. Would that be fair to say. Yeah yeah so. We were seeing basically between active and sedentary groups more equivalent mobility when it was kind of beyond the neighborhood so into town and beyond the town I think the sedentary was still a little bit less but it was more equivalent with third. The reported mobility okay and so for your active group when you guys broke those down even further right. You found that really levels one in three. We're kind of more indicative of people's Walking behavior level to crack. Yeah those were. The two were rehearsing more significant difference between the two groups. I'm the biggest. The largest difference was at that level three so at that neighborhood level. Yeah which kinda makes sense. But i was a little surprised to see that level to seems like it didn't have as much of an impact between the groups and do you have any theories as to why that might be. Yeah honestly it surprising not to see that in between level. Because when we're thinking about you know you have the difference between the inside the home and you know in the neighborhood and then you're not seeing it As much immediately outside the home. Do you think it's where these people live. So both of these centers are people are coming to our fairly urban our people living in an urban setting or maybe suburban where they'll.
4D: Deep Dive into Degenerative Diseases - ANPT
"parkinson disease" Discussed on 4D: Deep Dive into Degenerative Diseases - ANPT
"Right looking at their life space mobility. Did you correlate it to anything. Like how did you know what they were. Actually doing. Sure we have lifespan. Ability to capture kind of just participation level constructive getting out in the community but to equate that to like the walking activity to understand like what component of that was walking We use the stopwatch activity monitor. Which is just that. The ankle monitor they would wear that captures like steps per day in intensity of locking and such so. We're able to kind of look at a correlation between that walking activity with life space mobility source. Okay so the that life space assessment right asks people to look at the previous four weeks. When did they wear the monitor. So this was all baseline data so it was taken so they came in for their baseline assessment. In still out this life space assessment In general and then they went home with the device at that point after that and they worked for the next seven days. Direct okay and were. They being enrolled in a study with an intervention. Yes so the larger clinical trial had two different arm was just two different ways of administering a walking program like mobile health versus just a typical lake paper exercise program but this was all collected more baseline so before. Any of the intervention has started. Okay sounds my question. So the the the participants knew that they were in a walking study but they hadn't started the intervention yet correct and the participants what degree what. Severity of parkinson disease. It have mild to moderate. Okay so nobody who was Greatly impacted in terms of their mobility. Correct okay all right. And what kind of numbers did you get for. Step counts the course of a week average per day or whatever they believe the mean was about seventy six hundred stops per day.
Academy of Neurologic Physical Therapy Podcast
"parkinson disease" Discussed on Academy of Neurologic Physical Therapy Podcast
"Right looking at their life space mobility. Did you correlate it to anything. Like how did you know what they were. Actually doing. Sure we have lifespan. Ability to capture kind of just participation level constructive getting out in the community but to equate that to like the walking activity to understand like what component of that was walking We use the stopwatch activity monitor. Which is just that. The ankle monitor they would wear that captures like steps per day in intensity of locking and such so. We're able to kind of look at a correlation between that walking activity with life space mobility source. Okay so the that life space assessment right asks people to look at the previous four weeks. When did they wear the monitor. So this was all baseline data so it was taken so they came in for their baseline assessment. In still out this life space assessment In general and then they went home with the device at that point after that and they worked for the next seven days. Direct okay and were. They being enrolled in a study with an intervention. Yes so the larger clinical trial had two different arms. It was just two different ways of administering a walking program like mobile health versus just a typical lake paper exercise program but this was all collected more baseline so before. Any of the intervention has started. Okay says my question. So the the the participants knew that they were in a walking study but they hadn't started the intervention yet correct and the participants what degree what. Severity of parkinson disease. It have mild to moderate. Okay so nobody who was Greatly impacted in terms of their mobility. Correct okay all right. And what kind of numbers did you get for. Step counts the course of a week average per day or whatever they believe the mean was about seventy six hundred stops per day.
Academy of Neurologic Physical Therapy Podcast
"parkinson disease" Discussed on Academy of Neurologic Physical Therapy Podcast
"A lot more. I think sometimes about the insight these disease processes get yourself so a support group. Those kinds of things you really. I think when i first started that was probably the best piece of advice somebody gave me because it really let me see from the bottom up what people were dealing with But those the organizations that i mentioned probably the three biggest lewy body dementia association the msa coalition than of course europe esp. You can always go onto the mayo. Clinic has some great resources. You can look at Nord also has some things that are out there. And sometimes good old mr google you just type it in and you never know what comes up. i also. I don't tell my patients to frequently do this. But i will search on facebook for groups that are out there and sometimes you can find some good information a lot of times nations. It's not good information so no it's better for the therapist to be the one to kind of see what's out there but i would say you know rely on the big organizations that are out there. Of course the parkinson found station. I'm does a lot of great education. Not only in parkinson's disease but also in the typical. So if you're ever feeling really lost and have nowhere to go. That's a great place to start in. How would you direct physical therapist listening. Who wants to start some aspect of in their pt. Connect you know our clinic. Our doors are open. We would be happy to talk to therapist if they want to. Email us because honestly there's there's so few of these centers who have this ability to have this team and it's a lot of therapists like you said like you. They're out there. And you're seeing lots of these folks and sometimes you can feel like an island all by yourself And then there's always you know reach out to your local neurologist who's a movement disorder specialist and say. Hey you know what you're sending me some of these patients. I wanna learn more about this than i want to really provide care. Is there anything we can do to kind of talk together to do this. And bottom line is this katie. It doesn't matter what the diagnosis is. They are human being with functional. Needs if you strip everything away and you get the fundamentals of..
Project Voice - Healthcare Summit - 2021
Canary Speech: At the Intersection of Healthcare and Technology
"Canary speech has a full range of technology in our platform from a well developed extensive capability app. Available Apple and Android, of course. It operates on smart devices in multiple languages, we're currently deployed in Japan in Europe in Mandarin, and we've are entering the birds again market in Portuguese and of course in the U.S. and Canada. So we function within that app to be able to customize it for specific applications, whether we're dealing in stress anxiety or Alzheimer's or Parkinson's disease or congestive heart failure. We have a range of engagements across more than a dozen hospitals in the world right now, where we're validating the initial models within the clinical environment for commercialization on those. We also have a well developed set of APIs that allow us to do multiple things, of course. One is to connect to internal health medical record systems. But also some of our some of our clients have existing apps and we interface to those in augment those apps through providing access to our technology stack and analysis of audio. With the same performance returning within three seconds, scores to arrange a different locations depending on what the application
Project Voice - Healthcare Summit - 2021
Canary Speech: At the Intersection of Healthcare and Technology
"Canary speech has a full range of technology in our platform from a well developed extensive capability app. Available Apple and Android, of course. It operates on smart devices in multiple languages, we're currently deployed in Japan in Europe in Mandarin, and we've are entering the birds again market in Portuguese and of course in the U.S. and Canada. So we function within that app to be able to customize it for specific applications, whether we're dealing in stress anxiety or Alzheimer's or Parkinson's disease or congestive heart failure. We have a range of engagements across more than a dozen hospitals in the world right now, where we're validating the initial models within the clinical environment for commercialization on those. We also have a well developed set of APIs that allow us to do multiple things, of course. One is to connect to internal health medical record systems. But also some of our some of our clients have existing apps and we interface to those in augment those apps through providing access to our technology stack and analysis of audio. With the same performance returning within three seconds, scores to arrange a different locations depending on what the application
WTOP 24 Hour News
Jesse Jackson and Wife Hospitalized With Covid-19
"Jesse Jackson and his wife, Jack will and are both hospitalized in Chicago after testing positive for Covid 19, the same civil rights leader and presidential candidate is vaccinated but also has Parkinson's disease. Statement from his nonprofit group says doctors are monitoring their conditions and will provide UPDATES when available.
Double Date with Marlo Thomas & Phil Donahue
On a Date With Reverend Jesse and Jacqueline Jackson
"It was a bitter cold november morning. When we got to the airport we were heading out to chicago. My old stomping grounds to visit reverend. Jesse jackson and jacqueline jackson not only are these two civil rights icons his work with martin luther king her lifelong activism. But they've been married throughout all yearly sixty years. I was really looking forward to it only problem. Our flight from new york was severely delayed and we were five hours late for our date. It was awful. I really hate being late for anything but even though it was already evening by the time we landed. They said come on over anyway. I've known them for decades and that's the kind of generous people. They are The children well. They all still talk to me. That's a good side. Jesse was diagnosed with parkinson's disease several years ago but despite his condition his spirits were lively and jackie. She's always full of life. As we settled in jesse began to recall their early days in college. She was a into modern dance and she had been librar- and beautiful begun. Measure parents versus freaked on her bills. A-plus all the time though the pluses so you beginning you say wait. What would values you share. The foundation was marriages. Don't last long as they have. No the norwich told free. Russa's deep is larussa foundation when the wind blows can't take it as i see what roles without roots. It cannot grow right over. How lucky you were to find. Jackie i mean other women would have run out the door because you were never home. I love you. I was lucky. I told him because he was going and going and going and then he wouldn't inform me. I went to him. And i said reverend. You're supposed to make me abbey. And i was. I mean because i really felt a man is supposed to make you happy. That's his
The Exam Room by the Physicians Committee
"parkinson disease" Discussed on The Exam Room by the Physicians Committee
"Dr agarwal will be doing a far deeper dive into her research. At this year's international conference on nutrition and medicine the conferences running july fifteenth through the seventeenth and will be available on demand for a while after that even so. It's not too late to sign up and the cool thing about is that dr agarwal is just one of about thirty leading voices on health and nutrition who will be coming together to present the latest fact and evidenced based nutrition science. We are talking about credible information here. We're not talking about something that your grandma heard from somebody in church. We're not talking about something that your friend saw on twitter. We're not talking about your third cousin. Twice removed nutrition advice that they saw on instagram. No this is the real deal. Rentable research guaranteed to raise your health. Iq and you've actually heard a lot of the feature presenters on the show recently and this is your opportunity to get even more of that research. Go more in depth. P. c. r. dot org slash icy and is the website that you need to visit an order to register and use the code exam room to save fifty dollars and because the conferences online. This year you can literally join it from anywhere in the world. And i do hope to see you there. Let's head now to the exam. Room news desk. A new study is offering hope for relief from uncomfortable often unbearable hot flashes that occurred during menopause. It turns out that a plant based diet that is rich and soy can reduce moderate to severe hot flashes by eighty four percent. The promising findings come from a study by the physicians committee for twelve weeks. A group of women ate a plant based diet that included soy and according to researchers the average number of hot flashes each day fell from five to less than one and nearly sixty percent of women who participated in the study. Say not only. Did they have fewer hot flashes. They stopped having them all together. The study is published in the journal. Menopause we'll be doing a series of shows on this study. It's called the wave study and you'll hear many of those study participants. The women who went through this experience. Those changes firsthand. You'll also hear from dr neal. Barnard who helped lead the research and other experts including dr christie. Cobb stay tuned for that in the coming weeks but today's show was about alzheimer's disease and parkinson's disease and the incredible research that is being done on them. It's research that's all of us. Hope for the future. And that is why i am so honored that this episode of the exam room is made possible by today's dietitian and today's geriatric medicine. Today's dietitian is the leading independent source for news. Information and research for registered dietitians and nutrition professionals and today's geriatric medicine provides important relevant and timely content for geriatric physicians and the entire geriatric care team. Learn more about these trusted and respected public ations at today's.
The Exam Room by the Physicians Committee
"parkinson disease" Discussed on The Exam Room by the Physicians Committee
"To be given to everybody like okay. I'm consuming good food. But then there it is important that we also limit our unhealthy options Because in one of the recent studies we did. We found that those who were consuming more of these kind of unhealthy food items. They were Categorize more of the western diet had a did not have the impact of their Good food which they were eating so overall what. You're eating Does impact on like whatever bad yard. I am using the would bad but it's again like just like not not really bad but considered unhealthy will be like more fried food sugar for would end of that can affect night diet so consuming vest nights kind of diet was Attenuating the beneficial effect of all the good food. People were eating in the school. And this shows there's something happening there is there is this interaction or there is Some interaction happing definitely with between the good and the bad food in our diet so we have to. It is important that we have to limit. How much of unhealthy you can eat. So that's by mind either. Communication for example is like just limit your fried food intake to less than or equal to once a week. So let's not do it so regularly that you are diminishing the effect of all the other good foods. We have had in your breakfast lunch so in the if you wanna be needed. I'm just probably make it once league rather than just grabbing it everyday so so there is there is the study we have done ended probably the expanding more about the results in the conference upcoming conference. But that's definitely something we've found Patio boss effect. Like the bachelor had on the good ol boy all right now. That is something definitely to look forward to. And that conferences. Coming up july fifteenth through the seventeenth. And you can save your spot right now by visiting. Pcr dot org slash icy and reserve your spot today and by the way if you use promo code exam room all one word you can save fifty dollars off the cost of registration right now. So crm dot org slash icbm to reserve your seat and dr agarwal. I know you're going to be diving deeper into science. They're one of the other things that you're going to be covering And we're not going to go into this now because we have to save something for the conference you're also going to be looking at emerging research on pre and probiotics and gut health in terms of alzheimer's and parkinson's disease as well so this is all very fascinating and i just. I can't wait to sit down and watch the entire presentation and yeah. I think that's another area would just developing i said like a this nutrition unity Disease area is definitely very interesting and still developing and one of the aspects Which is People are like different groups. Autograph award looking at is the gut rain access. So did they say like the food we eat affect your gut microbiome affect your like overall diversity in microbiome and might have impact on brain health. So these are the new areas of research Where people delving in a like every every day they're like new answers on interesting Things are discovering related to this and so probably one of the mechanisms through which a healthy diet is working or helping your brain possibly can be through got. Don't you just love your job being able to study this day in and day out like isn't that just fascinating. I love what i do. And i think all of these interesting question. Just let me get up everyday and work more harder to make to look deeper and we are also trying to delve into more mcadams which is lock more exciting. And i guess i'll probably one of the few centers disease center. I think we are unique place to release. Study the effect of nutrition on brain up because we have these studies Collecting rains at the end of life. So we get all these bar savino what they aid in their lifetime. And now after post-partum. I mean we are looking at their brains than trying to link if there is an association with alzheimer's disease Or something else in their brains. We're trying to also established mechanisms link which really expand in for the Define or really like say how how might be affecting overall brain house so that's really exciting. So yes i do. Love may jail but it's it's exciting. It's fascinating but most of all it's important work. That is going to go toward improving the quality of life for so many millions of people worldwide and their family members their loved ones as well. And so that's why. I'm so grateful for everything that it is. You are doing and also for taking the time to join us here today. This has been an absolutely fascinating conversation. Thanks too much shock. It was a pleasure to be here. And i think talking more about this in the presentation and the upcoming contract so stay tuned.
The Exam Room by the Physicians Committee
"parkinson disease" Discussed on The Exam Room by the Physicians Committee
"Get those crat noise. Yea like i. That's what i think. One of the mantras which most of the dietitians and nutritionists say tell everybody do follow is like have colorful blade but all the colors on your great so Just try and grab a colorful rule and vegetables and like tried to include as many as you can because all of these like hot like even the beats like purple color pink color they will specify correct noise and like for example greens a lot of latino which is another important type of keratin which have shown good evidence for its role in brain health. So yeah trying to be colorful on your plate. Well here's a question for you and wanted to just kind of popped in my head right now. Would you say a and obviously going to preface this by saying that they both have remarkable health benefits. But would you say that in terms of our discussion today. Is it possible to say whether fruits or vegetables play a bigger role. Can you even break down. Yes so that has been broken down in some of the studies on like fruits versus vegetables. So there are like other studies from Not only argo broad from other groups including nurses health study and help professional a studies alike. The bigger go hordes which really looked at the effect of fruits and vegetables looked at them separately for its effect on cognitive hell and primarily. The the results are more robust for vegetable intake rather than fruit intake like fruit had kind of mixed findings than some of the studies have found only some positive associations with cross-sectional cyanide like rude associated with cognitive function. But not maybe as much a t plans so there is no report on crew associated with cognitive decline. But there is a strong Like a raw good evidence on vegetables and primarily green leafy vegetables for its effect as up. There's also some evidence that corsi And cognitive decline. So i would say vendor comparing fruits and vegetables vegetables. We have more stronger evidence but from like the overall food category. There is more evidence coming from berries. Definitely so we have blueberries and strawberries and raspberries. All the betty. Category has shown evidence but not like Quitting through together as one thing. I mean there are few reports on fruit juices here and there but not that robust i would say to westerville the berries. I think it has to go back to those antioxidants. You were talking about earlier right now. You know speaking going back to things. It always goes back to green leafy vegetables with these types of studies. Too doesn't it. Those things are a nutritional powerhouses yes Let's let's talk a little bit more about this research. Okay so we talked about the mind diet. You also looked at the mediterranean and dash diets here A what what did you find. As far as their effectiveness. Compared to the mind diet zil a in our city specifically a kind of try looking at boga tree died. Scores like simultaneously and Trying to compare the standardized speed as like standardized effect size would say in scientific terms and the found excessive agree for mind diet those who are given zooming moderate and high a mind diets were having good effect overall had reduced risk of alzheimer's dementia. But when we're looking at mediterranean scores of the dashboard denver This effect was evident only in those with high adherence. So like probably take home Message from that paper. That particular paper that dr mark From joining fifteen Which was published in amazon dementia was even like a moderate to hide. It ends of mind diet Abbas dementia risk for mediterranean dash. We found only the highest darren's but this associated with geus risk. I'm curious for these studies. Did you also factor in things like exercise and getting adequate amounts of sleep. So far does steady. We do have physical activity in our model out. Also a study on parkinson's signs of an anti new we did include So we have a physical activity and view for cognitive outcomes. The also include the cognitive activities elite life interactivities people have been engaging 'cause that's another Lifestyle factor which has been found to be associated with cognitive outcomes. But we do not have a sleep in our model specifically. I think that's another area with still developing. I would say and let me ask you this okay. So there's no question they you and i. We live in a fast food obsessed nation. It seems like you can't go a single street or one block without seeing a mcdonald's or a burger king a chick-fil-a whatever. The case may big. If everybody that let's say not everybody let's say someone Is doing really well. They eat healthy for breakfast. They eat healthy for lunch They're exercising okay. But then every night on their way home they stop at the drive thru and let's say that their vices that big mac and fries so if they eat healthy the majority of time but still have that fast food once a day you know. What does that do in terms of their risk for developing either alzheimer's or parkinson's disease here. The that is a good question. I think that's an important message also.
The Exam Room by the Physicians Committee
"parkinson disease" Discussed on The Exam Room by the Physicians Committee
"Brought to you by the physicians committee high. I am the weight loss. Champion chuck herrell. Thank you so very much for racing your health. Iq with us this episode fifty seven from season four number two hundred fifty two overall and today. We are going to be talking about not just alzheimer's disease but for what i believe is the first time here on the exam. Were also going to be talking about parkinson's disease and so today. I'm going to be joined by a woman who is devoting her career to teaching and researching both of them and she is a nutritional epidemiologist. Ed rush alzheimer's disease center as well as an assistant. Professor in internal medicine at the department of clinical nutrition at rush. Doctor pooja agarwal. She is here today and she will be looking at the cognitive and motor declined that those living with alzheimer's and parkinson's will experience. How much of a role does nutrition play though in preventing that decline in slowing that decline. We're going to be looking at a number of diets putting them head to head and seeing what effect they may have had and we'll get her opinion by the way as to whether fruits or vegetables might have a bigger impact on these diseases and then coming up. After the interview with dr agarwal i will have details on exciting new study. That shows a change in diet can reduce hot flashes by more than eighty percent more than eighty percent brand new data. Coming your way critically important and very exciting for the three out of four women who will experience hot flashes during menopause. Stay tuned for that. But i a conversation that i hope will not just raise your health. Iq but also raised your spirits because there are ten million people worldwide right now. Living with parkinson's and another ten million are expected to be diagnosed with alzheimer's disease this year alone. So let's all join together and head into a healthier future and take those first steps right now.
Colleen and Bradley
Robert Downey Sr., Actor and Filmmaker Dad of Robert Jr., Dead at 85
"Downey Sr. Actor and filmmaker Dad of Robert Downey Jr has passed away at the age of 85. He passed away in his sleep in New York City this morning. According to the Sun. He celebrated his 85th birthday last month that you might not know Robert Downey Junior's dad actor in his own right. He appeared in movies like Boogie Nights, Magnolia to Live and Die in L. A. And Downey Sr had been battling Parkinson's disease for more than five
Does This Happen to You
How A Tiny Dog Helped Me Find My Way
"My dog's name is pepper. And i got him in the spring of two thousand six which is also the year. Both my parents had cancer. I was almost old enough to rent a car. But not quite. I lived at home with my parents. Well i lived with my dad most of that year because my mom was receiving cancer care out of state but more on that later. My dad also had parkinson's disease. I had graduated college three years before and in the inbetween time. I'm not sure exactly what i did. Other than quitting law school after six weeks checking out books from the library and surfing the internet which must have been boring. Because i probably had a super slow connection and there was no twitter. I also started working at a tennis club. Maybe ten to twelve hours a week. I was existing. But i didn't have anything close to a clear direction. Then my mom got diagnosed with a serious type of cancer. My dad got diagnosed with a less serious type and everything suddenly felt super dark. Like hell the florida skies become ferociously black when the massive summer thunderstorms descend. I don't remember what was going through my head during that time. I didn't keep a journal. And the only thing i'm good at remembering is random sports stuff but it seems likely. I felt scared and isolated while my mom was away undergoing multiple surgeries my dad and i- cohabitated in our traditional fashion. We mostly kept to our respective of the house and bumped into each other at mealtimes and when he wanted me to drive him to lows or the driving range so maybe. It's not so surprising that i decided i needed a dog to keep me. Company the chihuahua. All my parents got me. When i was five had died three or four years before so naturally the only type of dog i considered getting was a chihuahua
Acupuncture is my Life
"parkinson disease" Discussed on Acupuncture is my Life
"Expresses is slow movement and you'll express his like having difficulty brushing your t.'s. Cutting sandwiches or dicing fruits or buttoning coast or your shirt things of that nature and it usually affects just one side of the by slice slice but it eventually moves to the other side of the body as well due to the reduction. Dopamine excites spoke about like dealing with bladder problems. Just another warning sign is trembling web trembling of the feet shuffling defeats trembling hand even your jaw slice and upwards of about sixty five to seventy percent of individuals with parkinson's suffer from trembling symptoms. Which is very very interesting. Ice another is rigid movement posture. Changes you into slouch. Experiencing muscle stiffness slice. The spinal is effected in those with this disorder. You may also experienced painful muscle cramps. That affects your movement. Another is balanced problems. Slice many individuals with parkinson's have trouble balancing themselves while changing positions and this is due to the degeneration of nerve cells in the area of the brain that controls your balanced early stages the balance problems will be pretty mild and many will try and overlook like ours just temporary but it does progress but even when you begin to notice yourself struggled with your balance. She adopted seen acupunctures. Contact acupunctures my life right away. Don't wait no need to wait. Another can be freezing in movement. Slice your attempt to walk in. You'll feel like you froze like what the heck is this slice functions and then you may start walking and then as you're walking you may fleas again. My slice another warning sign but now this symptom usually slight expresses itself in the more advanced stages of parliament at pain which can come in many forms. You know you can also experience numbness but the pain on the body. That you feel will be stabbing won't won't be a stabbing field to you also express or experience burning sensations. Usually we felt on just one side of the body slice now. Of course i was in asked you know how would an acupuncturist viewer diagnose sh- pocket zaslov. How would i analyze. The primary shift is an acupuncturist parkinson. And the three. Typical symptoms tremors brady caniggia muscle rigidity. You know when it comes to tremors like let's say constant trimmers let's say with numbness of limbs to an acupuncturist are usually the result of liver and kidney yen deficiency failing to nourish the sign news vessels slice now constant trimmers muscle rigidity accompanied by take significant lack of strengthen limbs show cold brady caniggia's shortness of breath with spontaneous. Sweating usually is as a result of our chee and blood deficiency with emptiness in the vessels in channels slice now the condition of intimate and trimmers accompanied by. Let's say heaviness of the body issues with keeping saliva in your mouth as i previously discussed to an acupuncturist dishes caused by wind. Flim complex is like within the body. Shwoing wind it usually manifests the trimmers obstructive flam presenters heaviness stiffness of the body or your limbs news deficient chief feeling to metabolize water which is a sign of phlegm accumulation. Now as the disease progresses to severe stage trimmers worshiping dysphasia skin slice with a quarterback. Tom now this to acupuncture student deficiency with blood stasis obstruct in the channels. So it'll give you. They can be four basic patterns to an acupuncturist of several more complex. But for basic ones can be delivering kidney insufficiency ci in blood deficiency wind flam obstruction of the collaterals deficiency with blood stasis throwing those basic patents out there you could be diagnosed in many ways and treated by with acupuncture..
Breaking Biotech
Will Selecta Biosciences be the Next Top Platform Biotech?
"The first company. I wanted to touch on is news from july lilly and they're huge company. Say like a large mega cap at one hundred and eighty three billion dollars and what they recently presented was the full data set from their molecule demand in alzheimer's disease. And this is a phase two trial looking at this antibody that targets a specific epoch on the amyloid beta approaching and this episode is only visible in established plaques. Now i don't want to belabor the point about the amyloid hypothesis which i've done in previous videos. Suffice to say that a number of different molecules have been attempted in this indication in specifically the mechanism of reducing amyloid plaques. And they've all failed and what we're seeing here is that in this multi center randomized double blind placebo controlled trial. That donna had a significant is what they're showing here in the air score but not a very profound impact on cognition and so they looked at this primary outcome the air score and this is a combination of the as well as the ads. Ads and so eight ask cogs general measure of cognition whereas the ads. I is a measure of activities of daily living. So they did a combined score with that and demanded mobs improvement led to a p value of point zero four so technically significant. But i'm not sure that if they replicated the stayed in a face. Three trout necessarily be positive. It is an interesting thing because when you look at the actual aid. S cog thirteen score. We don't see any significant change. It is better in indiana but not by a significant margin and then the mse score is basically no difference between the two so this is another data point to suggest that perhaps the amyloid beta hypothesis isn't one that these companies should be looking at and the last thing i wanted to show here. Is that the one thing that they do. See a significant change in the amount of amyloid in the brain and so the pet scan here to show that the dynamic treated group has a significant reduction in the amount of amyloid plaque in the brain compared to placebo. So the drug is able to reduce the emily beta plaques. But it's not able to improve cognition really as much as you would expect given the effect is there so i wanted to bring this up because there is an upcoming. Pdf date for biogen's advocating mob and this is going to be a huge movie for the stock and it was originally supposed to be in march but it was delayed until june seventh of this year. So keep your eyes on that. I don't know if i'm going to make any position on it. I think that the fda should not approve it given the results from the advisory committee but given that the so many is on this pdf. I feel like there's a chance at the fda could overlook that and end up approving drug. So it's definitely jairo word. Play and i would treat it as such and proceed likewise so that is eli lilly. I wanna quickly move on to another company in the alzheimer's face called novus and i touched on them in my previous video and what we heard in the last week was that they announced positive face to data and this is interim data showing the nbs for one or another name for the molecule is positive in improved speed and coordination in parkinson's patients. And this is a twenty five day treatment. Nine patients were in the treatment group and five or in the placebo and on the announcement of this data. I think the stock was trading around one hundred fifty maybe two hundred million dollars market valuation and went up to around two fifty three hundred before settling around two hundred and fifty million dollar market cap so big move up in the stock and i'll tell you the data. The ceo explained that the study was power to investigate a difference of twenty to twenty five percent in biomarker levels not to demonstrate efficacy making this data that much more significant so to provide some context. And why i think this is interesting. Is that i in my previous video. Didn't really seem to bullish on a novus and the reason for this is that it reminds me very closely other types of amyloid beta drugs because this drug reduces app the precursor protein to amyloid beta. So my rationale is that if they're targeting the same emily data pathway. Given that there's been so many molecules that have failed previously targeting that pathway. I don't expect that this one is going to be any different now. Having said that. I decided to take a position because we've seen over and over again. That companies have been able to spin face to data in a positive way that leads to these big increases in the sock even though in phase three there's an eventual failure so i decided to take a position in stock and i have been rewarded handsomely so far and i'm going to hold on to see the rest of the phase two data so to get the actual data here in one test that measures the speed of execution. The results were statistically significant. P equals zero point zero four showing that while parkinson's disease patients are slow in coding. Boxes met with an s four. Zero one improves their performance. In these same patients other test that measures coordination showed an improvement in their movements and was almost statistically significant peak will s- appoint zero seven. Then they say in all end. Es up tests performed the placebo group either stayed the same or performed worse than at baseline instead the a b s four zero one group either stayed the same perform better than at baseline and as we know. Md s up drs is a specific tasks that measures severity and progression of the disease.
AP News Radio
James Levine, who ruled over Met Opera, dead at age 77
"New York Metropolitan Opera conductor James Levine has died of natural causes in palm springs California according to his physician Levine was seventy seven I marches are a letter with a look at his career James Levine conducted for the Cleveland Orchestra in Chicago's Ravinia festival but his claim to fame was presiding over the New York metropolitan opera for four decades he conducted two thousand five hundred fifty two performances and built the orchestra's world class reputation he was forced out in twenty sixteen due to Parkinson's disease and became music director emeritus he was fired in twenty eighteen over allegations of sexual misconduct Levine had planned to perform this past January in Italy but the concert was canceled because the corona virus pandemic
Breaking Biotech
Continuing to Navigate the Neurodegenerative Disease Subsector
"The first thing. I want to mention of course is what we're really dealing with here when we're looking at specifically companies in the next generation space. Now i'm going to belabor the slight even less than i did last time basically for good phase three data. I feel it'd be good. Expect a company trade between at a minimum really of ten to twenty billion dollars market cap and for companies. That are kind of earlier in the pipeline. I would say they've shown some good phase one b or some good early phase two a data. We can expect them to trade around at one billion dollar market cap and that seems to be the case so far and there's obviously tons of information that we can use to say whether or not they should be trading at a higher value or a lower value than that. But that's generally what i'm going into this with and using the data that's available out there. You can really make your own assessment. What you think is a fair value for some of these companies but anyway just to show this slide quickly because we need to know what we're dealing with here so keep all that in mind as we look at the market cap of these different companies. Today and the first company. I want to touch on. Is a company called aspira. Fire ticker symbol. Ha they closed on friday. The fifth at nineteen dollars and eighteen cents a share giving them a market cap of seven hundred million dollars they're q. Three twenty twenty net loss was eight point five million dollars and they had a q. Three twenty twenty current assets of two hundred thirty two million dollars and then they also didn't offering in february of this year adding another hundred three million dollars to their balance sheet their q. Three twenty twenty current liabilities. Sit an eight million dollars and to give some background of the company they went. Ipo in september of two thousand twenty at seventeen dollars per share so they're not trading it too much of a premium for matt but for anybody looking to take a position in the short term. I do want to remind you that. The lockup occurs on march seventeenth and an additional twelve million shares. That were previously locked up from the ipo are now going to be added to the flow. Which is at twenty three point. Seven million dollars today. so companies. That had this lockup expiration. I caution against taking a long position in only because the dilution. That's going to occur after the lockup is going to put some pressure on the stock price so keep that in mind but the company is looking at commercializing an asset that targets the hypothesis that growth factor pathway also known as the met receptor. And they're doing this to try and treat different. Cns disorders so there specifically using compound called a t h one zero seven and this was previously known as andy x one. Zero one. seven if you're looking in the literature and they're trying to treat alzheimer's and parkinson's disease but this and then they also a small molecule version of this where they're going to be looking at neuropsychiatric disorders like depression. And there's some benefits to using a small molecule version verses the other version using a t h zero one seven. But i'm not going to focus on that. I'm really just kinda talk about the molecule. That's going to be treated for alzheimer's and parkinson's disease and before we do that though i did want focus a little bit on event related potential and a touchdown this on a couple other episodes but i wanted to go a little bit more in depth because the main readout that a fire is focusing on is this p three hundred data point and so what event related potential is a quick primer. It's a q. Eeg measurement but it's a functional version of that so a lot of companies will show a q. e. e. g. measurement of just baseline brain activity. And what this does is it. Just measures brain electrical activity and q. E. e. g. sanford quantitative electro So the baseline measurement is useful. I guess but what's more impactful is actually do a sensory event which is a better surrogate for actual cognitive ability.
The View
Rush Limbaugh, conservative radio titan, dies of lung cancer at age 70
"One of the most dominant figures in talk radio in an architect of the conservative media movement. Rush limbaugh passed away aged seventy from lung complications lung cancer complications. There's been an outpouring of tributes along with a lot of criticism of his decades of controversial comments. So the question is how will you remember my start with joy. Well i did work. I worked at a radio station in. Nineteen ninety-one ish around that time. Wabc radio and he. I came on at ten. I believe and then he was on at eleven o'clock so i was engaged with him quite a bit in those days over the years. He's called me more bihar. Which i thought was interesting. I guess he was saying that. I was like b arthur in the in the show. Maude who was a raging liberal. I presume that's what he meant. And i consider that a badge of honor to be compared to maud. But it's interesting. I worked with him. I worked i've interviewed ann. Coulter many times Janine pirro has been on the view trump has been on the view. I went to his wedding for marla You know these people have gone through some kind of metamorphosis of of weirdness over the years and i was getting used to come on the show. She was actually fun. Ann coulter is basically. I consider her a comedian. I don't even consider her a pundit and we all know what trump was like before you know he was a democrat. So what's what happened to them. And i answer is money. Money is what happened to them. They have thrown at so much money at them at fox for example and various places that they could not resist the money so they go on the air and they spew their hatred their prejudices their lies as rush limbaugh for the almighty dollar and they fool americans into believing that they are authentic authentic. I know these people. They're not real right. So sonny what do you think his legacy will be. Well i been listening to to everyone. Eulogizing rush limbaugh. And i remember listening to him as a kid growing up and for me. He just normalized Hatred he normalized racism. And you know. I think he really weaponized. White male grievance and you know he sort of hard in these rural white listeners people sitting in their trucks and in the middle of america and in the south and listening to rush limbaugh and this is someone who called our president barack. The magic negro. This is someone who talked about an nfl football game as a gang match between the bloods and crips. This is someone who made fun of michael. J. fox's a parkinson's disease this is someone who likened a thirteen year old chelsea clinton to a dog. You know this wasn't someone who Was a nice person. This is someone that spewed racism and hatred yet. He is now considered. I guess the most influence the an influential person and building the modern republican party and conservatism. A to me. That's not something to be proud of. I mean how is that. A reflection of conservative values i thought conservatism was about small government and family values and if family values is making fun of black people and a child and a disease. I don't know where the the republican party is. I think his legacy is that he paved the way again for the modern republican party and trump is
Science Friday
Charting of the Human Genome, 20 Years Later
"We're talking about challenges for genetic research. 20 years after the first draft of the human genome was published with my guests, Dina Zelinsky, a bio infirm, a Titian with the Paris transplant group. And elite scientists for civil tech and crystal, soc and indigenous geneticist bioethicist with Vanderbilt University and the Native Bio Data Consortium Crystal I introduced you as a co founder of the Native Bio Data Consortium. Which gets to an issue we've talked about in different ways on this program in the past indigenous sovereignty over genetic data, please remind us how big an issue this is. Yeah. So when we talk about precision, medicine and health were always promising that the next advantages and innovations will be conferred to those individuals that contribute the genomic information. The pandemic has shown that preventive healthcare and structural barriers to access to health care probably highlighted more about health disparities than this UN pronounced supposed to future advantages of healthcare. Indigenous peoples have You know, willingly or unwillingly contributed their didna for the supposed betterment of humankind Need I remind everybody what happened after the completion of the Human Genome Project. We had the completion of large scale diversity projects such as the Human Genome Diversity Project and 1000 genomes project, which were denounced by over 600 plus indigenous nations worldwide that went to United Nations because they were concerned. About privatization and commercialization and exploitation of indigenous genomes and what has happened to those biomarkers collected from indigenous peoples from Central South America. Those bio markers are now freely and openly accessible to companies such as ancestry, Didna and 23 Me ancestry. Edna has hosted revenues over a billion dollars every holiday quarter since 2017 so we always have to ask yourselves. What exactly are the protections? Really? This data privacy and commercialization. The rate of technology outpaces our regulations, these new technologies and while we think that these protections are conferred by laws, which is the genetic Information nondiscrimination Act Last change. Companies are bought and sold. So we have to ask yourself what's the commercial value? The data that we're being asked to freely give away and how can we look to communities and empower communities to self directed decisions that are being made using their data? Dina, you contributed your data, and you gave it away freely. Do you not feel the same kind of threat here that exist? Not quite in the same way. No individuals of European ancestry make up the vast majority of genetic studies, and that's really problematic because they only make up 6% of the population. And I, I completely understand the threats to underrepresented populations. We should be sequencing these underrepresented populations, but we should be sequencing them with the idea of Making genomics research more equitable of giving back to these communities, not just taking from them. That being said, I can't even explain how useful data like that from the 1000 genomes project has been. I've used it in most of my projects. I have whole human genomes at the tip of my fingers. When I'm accessing this data, as well as other scientists, I think We generally have good intentions, so I currently use it in a study to better understand Parkinson's disease. That being said. I think in many cases, a lot of this data has restricted or limited access for researchers versus commercial entities. I agree here that we we really should limit what industry can or cannot do with with our data. Krystal. You mentioned preventive care and the pandemic. The human Genome Project. I remember promised to tell us everything about her genome. Doesn't this sort of tell people Hey, we know everything about you now and ignore the nurture part of the nature nurture debate. What I can tell you as a geneticist. My first skepticism and what I always tell tribal leaders is that genetic data is just the easiest type of data to collect. But genetic data does not. Predict as much about disease risk than we think. Other things such as access to care, cultural factors, colonial factors relating to help probably contribute more to the health differences and outcomes than actual genetics itself. Things like diet environment and lifestyle are things that we should be looking at. And definitely socioeconomic status by factors. But these are the hardest bits of data to collect. And so we really can't build truly robust models without looking at these other factors related to health. So looking at genetics and biological factors is sometimes a little bit of a cop out. You don't necessarily properly convey the limitations of genetics and biological research to the lay
Academy of Neurologic Physical Therapy Podcast
"parkinson disease" Discussed on Academy of Neurologic Physical Therapy Podcast
"Out tng and started having this conversation. 'cause andreas really a clinical expert. In parkinson's disease was aware of the parkinson's disease edge documents and was really always kind of searching to kind of improve practice. So angie like thinking back to kind of those original conversations. What we're kind of some of your thoughts as i approached you about this project yet. Thanks amy i was excited about the project being a therapist for over twenty years and really knowing a lot about parkinson's i had been doing a lot of the outcome measures myself but knew that a lot of my co workers were not doing commercials. I was doing so. I was excited because it was a good way to really i think approached them and get their input that were kind of approach it as a team. How can we do more. Parkinson's specific outcome measures In provide more research based gill to to people with parkinson's i was super excited about it. Anti give us a little bit of background on your clinic. Like how many clinicians do have there. What kind of populations do you see. It's a relatively small clinic. It's outpatient neuro clinic so there are currently. Actually we have three physical therapists at this point. I'm part time physical therapists in two full-time. Pt's we have two fulltime. Ot's three speech therapist and to physical therapy assistants. So that's pretty much our team right now in the front office staff. Jim itself is actually small which came into play when we were deciding which outcome measures. We're going to choose so as far as the physical barriers That was something we had to talk about amongst the team as ours. What outcome measures were gonna work for us. So that was helpful when amy came in 'cause we could all sit together for us as a team. What are the outcome measures. That we feel we can implement and continue to. Do you know a forever and were there other clinics involved in this effort yes We're the mainero clinic. But there are several other outpatient clinics associated with essential genesis. And so i guess how many there was about there were four clinics that were involved in the project in particular because so the grand blinked. Clinic is probably i would say. India said the central clinic that sees primarily neuro patients but there's other clinics and other remote parts in the flint area. Down a patient with parkinson's might not wanna travel a half hour so these clinics were closer to their home in these clinics were commonly smaller clinics. Two of the clinics only had one physical therapists. That was at that clinic but that would still see somebody with parkinson's disease. The project included four clinics that included seven physical therapist to occupational therapists..
4D: Deep Dive into Degenerative Diseases - ANPT
"parkinson disease" Discussed on 4D: Deep Dive into Degenerative Diseases - ANPT
"Out tng and started having this conversation. 'cause andreas really a clinical expert. In parkinson's disease was aware of the parkinson's disease edge documents and was really always kind of searching to kind of improve practice. So angie like thinking back to kind of those original conversations. What we're kind of some of your thoughts as i approached you about this project yet. Thanks amy i was excited about the project being a therapist for over twenty years and really knowing a lot about parkinson's i had been doing a lot of the outcome measures myself but knew that a lot of my coworkers were not doing commercials. I was doing so. I was excited because it was a good way to really. I think approached them and get their input. We're kind of approach it as a team. How can we do more. Parkinson's specific outcome measures In provide more research based gill to to people with parkinson's. I was super excited about it. Angie give us a little bit of background on your clinic like how many clinicians do have there. What kind of populations do you see. It's a relatively small clinic. It's outpatient neuro clinic so there are currently. Actually we have three physical therapists at this point. I'm part time physical therapists in two full-time. Pt's we have two fulltime. Ot's three speech therapist and to physical therapy assistants. So that's pretty much our team right now in the front office staff. Jim itself is actually small which came into play when we were deciding which outcome measures. We're going to choose so as far as the physical barriers That was something we had to talk about amongst the team as ours. What outcome measures were going gonna work for us so that was helpful. When emmy came in 'cause we could all together for us as a team. What are the outcome measures that we feel we can implement and continue to. Do you know a forever and were there. Other clinics involved in this effort yes. We're the main neuro clinic. But there are several other outpatient clinics associated with essential genesis. And so i guess how many there was about there were four clinics that were involved in the project in particular because so the grand blinked. Clinic is probably i would say. India said the central clinic that sees primarily neuro patients but there's other clinics and other remote parts in the flint area. Down a patient with parkinson's might not wanna travel a half hour so these clinics were closer to their home in these clinics were commonly smaller clinics. Two of the clinics only had one physical therapists. That was at that clinic but that would still see somebody with parkinson's disease. The project included four clinics that included seven physical therapist to occupational therapists..