20 Burst results for "Mouser"

How the gut protects the brain from infection

The Naked Scientists

05:10 min | 2 months ago

How the gut protects the brain from infection

"A brains sit cocooned inside a series of protective layers. They called them in injuries. And these together with a structure called the blood brain barrier keep out unwanted bugs nasties that could otherwise prove lethal forest. But how exactly the brains defense systems do. This wasn't known now. A new discovery is added an important piece to the puzzle specialized plasma cells these a blood cells that make antibodies is important potentially harmful bacteria in our intestines and then make their way up to the outer part of them in indies called the juror where they churn out antibodies and keep the brain bug free medical worthy. The thing that really got me interested in thinking about the brain is that there's increasing evidence that the immune system plays a role in a number of brain disorders so things like depression and anxiety and even the progression of neurodegenerative diseases like parkinson's disease as well as that. We know that the immune system is required to defend parts of the body from infection. So this could be important for defense against infections in the brain and in the ninja. So things like meningitis. How did you them. Pursue this to try and work out. How the brain was actually fending off infections. As with many studies in immunology we use mousers as a model and so the first thing that we did was to take meninges and look at them under the microscope and they were plasma cells in the sierra and they were not just got anywhere. They are actually lined up along. The border of large blood vessels that run through the zero. The these bug vessels are called venus. Sinuses the next question. When we find these plasma cells was empty they were producing to all surprise. We found that rather than producing igt. What's normally find in the body. They were actually producing an antibody. That's normally found gut so you've got this interesting observation an- tomic clear in the first instance of blood vessels running through. Jeez they've got cells that make antibody lining up along them. But the antibody they're making is one that you would not normally associate with the bloodstream. It's one that you would find in the testing. Yes so that was surprising. And i guess the next question was well duty cells actually originating the guts or are they influenced by the gut so to answer that we were able to use. Mice have never seen any sort of bug. They have no bacteria or any microbes in their intestine and when we looked at the dura from these animals they were no cells whatsoever but when we added bacteria back into their gut suddenly again the antibody producing cells reappeared in the era and even if we only eat put one type of bacteria into these mice a type of bacteria that couldn't go anywhere other than the gut we still saw the cells reappear in in the dearest that told us that those cells originated in the intestine. Your sort of hypothesis is the bacteria in the intestine. They educate the immune system and immune cells the intestine and what the cells then migrate from the intesting with the knowledge of how to make antibodies against those specific microbes. Up to the brain and take up residence in the meninges around the brain exactly and they specifically take up residence at the border of these d'oro venus sinuses. And i guess then the obvious question will why. Why would that happen. Why is the system being set up and the obvious answer would be. Maybe those cells there to protect The brain from microbes bacteria that originated in the gut into the bloodstream. When they're flowing through those at venus sinuses where blood flow is quite slow. It's an opportunity for the bugs to get out into the brain so to test that what we did was to remove all of the antibody producing cells and then we challenged mice with microbes into their bloodstream. And what we found was the bugs were able to get a cross into the brain as so it told us that really. We found a whole new defense system for the brain. What are you going to do next. We're interested in the signals. That might take the plasma cells from the gut to them. And jeez and then the other thing. I'm really interested in is whether this has implications for how we try and protect people from meningitis at the moment. If we vaccinated against meningitis we give that vaccine into the muscle but our study would suggest that actually if you want to make cells to defend the brain the route that you should give that vaccine is actually via the gut and so that's something that we look into the bodies a clever all thing. Isn't it minute klatt worthy there. She's basically comes university. Study describing that work has just come out in the journal nature.

Parkinson's Disease Meningitis Indies Anxiety Depression Klatt Nature
Apple may develop an iPad keyboard with a built-in trackpad

9to5Mac Happy Hour

04:50 min | 11 months ago

Apple may develop an iPad keyboard with a built-in trackpad

"It says a new report from the information and it is pretty big in the world of apple it is. That apple is apparently developing an IPAD pro keyboard with a track pad so smart Keyboard With Track Pad Allah Microsoft surface. What do you think that meal right? So the what we've seen in sentiment for he's definitely an investment in keyboard support for IRS. Right so we've seen stuff like the key down key up event stuff at the remapping of the keys. We've oh say had correlating evidence from Lake Michie choir who said that was going to be new. Small key bowed coming this year. Didn't he say Backlit Gitanes? Did you data time. So that was why. He translated to be glowing. Okay yeah so maybe black backlit from from glowing but this time and I think back is possible because the like unlike every other people in the market the apple. Kibo challenges guesses power through the small connector and in running one day basically to back lie on the keyboard is pitiful power can drain compared to power yacht. Pat Screen. O'day long yeah. I quite specific on average white. Backlit I think back lays patterns within the realm of possibility and none of those publications mentioned anything about track pads. This is in a new from the information today. This we haven't seen any like code references. Yeah this point. Of course if it was something apple was like seriously developing. That might be one of the things where they've really tightened down in stripping out the you know the bite releases ready to go and the status quo of of discursive put in general or Mouser put his That it's it's an accessibility feature starting with Iowa's thirteen that improved the Beta process. It was rougher than than when they actually shipped it But it's it's it's billed as accessibility because of you know. That's that's what the ideas in mind is that it's it's To be on alternative to touch input to replicate A finger but with a compatible mouse of some sort now the rules for what's compatible is all over the place and it seems to change so it's very complex Carcase what even works with it and then if it works with it how well does it work with it And you can go pretty power user heavy if you're using for ability and really trick out like a Logitech Amex master mouse and assign actions to all the buttons on it and the buttons. Yeah I've done that for the sake of you know just trying it and seeing what. It's like You can get the the cursor on screen you can make it pretty translucent. And so that's not in your way you can shrink it down because the color of it. But it's not a cursor to circle. The only thing that for me was like this is totally neccessity feature. Not you know even like work around track pad mode or mouse mode is that you've also got that virtual home button always on the screen which is to touch. You can make that super transparent but it's always going to be there and it's always a tower that you've got to avoid so that was my biggest hang up on it but nonetheless that is in the code for the first time like as a feature you can use with Irish thirteen as groundwork for something more to come. You know right now. Inaccessibility for reason in the is not like a general is not meant to be a general customer each other even just basic things. Like scrolling with it is not the fluidity in seamlessness and niceness that you would expect from if they were like Democrat on the WWE CDC stage right like it's a steadily inaccessibility for the fact that it meant for people who struggled to actually have have motor problems with the hands and moving a secondary input devices better than doing direct administration on the screen. Of course it could definitely like foundations for our proper Kashima proper mass thing. But I I don't like the idea of putting appropriate Assir on. Irs philosophically and they sent me been no like striking gun. Evidence that they're gonNA do

Apple Pat Screen IRS O'day Lake Michie Kashima WWE Logitech Mouser Iowa CDC
Jimmy Kimmel ditched his studio audience for a somber tribute to Kobe

Mason & Ireland

05:29 min | 1 year ago

Jimmy Kimmel ditched his studio audience for a somber tribute to Kobe

"Jimmy Kimmel. Who does this show from here in L. A. had coby on his show fifteen times times and was so affected By the accident and by his death that he decided to send the studio audience home last night he did not have a studio the audience and he opened his show by saying this. Hi I'm Jimmy Kimmel and tonight show is going to be different from our usual. We'll show we don't have a studio audience here tonight because going forward with a comedy show didn't feel right considering what happened yesterday. So I'd like to speak to you. Directly we as you undoubtedly know Koby Bryant and his daughter Jonah and seven of their friends were killed in a helicopter crash yesterday here in Los Angeles and that was a punch in the gut for many of us. Kobe was and I know this might not make sense but he was just the last person you could ever imagine something like this happening to. He was so strong and handsome and smart and energetic he was a hero. And when I say that I don't mean hero like real heroes like firefighters or doctors and nurses who actually save lives. I don't mean to compare what he did for a living moving to what they do. I know there are more important. Things have basketball. Almost everything is more important but Kobe was a hero in the way. Superman is a hero. He was so big. It was almost like he was a fictional character. A real life superhero with a costume and everything walking amongst us. Those of us. Who Love the Lakers? No it seemed like he always came through. He always showed up to save the day he wanted to save the day. He had a force of will will. He never gave up as an athlete. He was incredibly gifted more than almost anyone. He was talented beyond reasoning. Yet he worked harder than everyone. He work harder than people with much less talented he had. He took his job and his pursuit of excellence so seriously he was completely dedicated to being as good as he possibly could be which is inspiring to anyone who does anything and we loved him because of that but we also loved him because he was ours we watched him grow up here he came to La when he was a teenager and unlike almost every other superstar athlete he never left in his twenty year career he will only wear to uniforms. Forums for the Lakers and for the United States Olympic team. There were times when it seemed like he would leave but he didn't he stayed until the end and e someone almost everyone in. This city loved not just Lakers fans. Everyone would light up when they saw myself. Many times he was special he was a special person a great basketball player for sure but more than that he had so many interests outside of sports he was intensely curious he would call people. He admired to interview them. Business leaders writers inventors. He was always learning always improving hunger for that when he was injured when he tore his Achilles. I sent him a book and he to my surprise prize's read it and then called me to discuss it in maniacal detailing want to know everything about it and then I was like. I don't know Kobe. I didn't write it. I just bought the book and I had to put them in touch with the guy who wrote the book and that's what he was like. I'd many conversations Kobe off of television and they always involved his daughter's water's always you. Once retired for basketball his life revolved around their lives. He was very proud of them. He loved being a father when my son had heart surgery he he checked in with me repeatedly he made a point once. Billy my son was out of the hospital to meet him. He wanted to meet him and from time to time. You check in to see how he was doing and yes I know he was not a perfect person. I understand that a my intention is not to canonize him or or make judgements about things. I don't know anything about but I will say he loved this family. He worked very hard and he brought a lot of joy to a lot of people in this city. And we're going to miss him and I hope you'll pray for his daughter Jonah. And for their mother Vanessa for the three girls. Kobe left behind lost their father and their sister and his friends were on that flight. Within the Altobelli Family Christina mousers family. Chester family are as a buy-in the pilot. I can't imagine how much they are missed. This was a terrible loss for those families and the Lakers for Kobe teammates fans. It's just there's no silver lining here. It's it's all bad. It's all sad. He was a bright light. And that's how I wanNA remember him and you're hitting all sorts of reactions like this Carmelo Anthony any now. Just put up an instagram post. Chris Paul put up an instagram posts. I think people are starting people who have been able to utter a word the last two days. We've seen Lebron last night now. Carmelo and C. P. Three today read part of the Carmelo. Anthony Post he says I hate when I have so much to say but I can't put any of it into words the times I have the most to say are the Times that I can't talk. I'm screaming inside but I can't be heard you don't know how hard it is to pretend to smile when I have these clouds of emotions you you just called me and told me you were coming to the game Friday and that you were proud of me so colby colby had talked to Carmelo and was planning to be at the game Friday night

Kobe Lakers Basketball Carmelo Anthony Jimmy Kimmel Los Angeles Jonah Altobelli Family Christina Mou Koby Bryant L. A. Colby Colby Anthony Post Chris Paul Lebron Billy Vanessa United States Olympic Team Chester
"mouser" Discussed on KCRW

KCRW

01:56 min | 1 year ago

"mouser" Discussed on KCRW

"Tomorrow and again on Thursday as well so stay tuned for that I do before we end the program today because other people died in that helicopter crash I want to name them as well not only Kobe Bryant and his thirteen year old daughter Tiana but also John Altobelli Kerry also valley Alyssa Altobelli Serra Chester Peyton Chester hours of by and and Christine Mouser Christina Mauser who died on that fateful day on that Sunday in the hillside between Malibu and the valley thanks for being with us on stage here take this for all of us here greater LA thanks for you here and for your time have a great day okay said Debbie this is DNA design and architecture I'm Francis Sanderson how do you keep luxury retail relevant on main street you double down yes you can get you know everything you one with two clicks at two o'clock in the morning in your bed but when you're going into a so you want a personal connection you want the Croatian you won this pays that inspires you but how about the web stuff designed by David at J. at the Beverly center first up a story building in downtown Los Angeles has opened its doors to a new tenant the co working space come social club Noida house there are very few buildings that evoke an immediate emotional response to pretty much anyone that walks in and and that's what you get when you come into the atrium of the bribery building we have no I have CEO Josh what in a moment first let's go down memory lane I'm a coal have the mall first Brach rebuilding came into being DNA selfish I out see it went into the archives many of us first saw the Bradbury building in the nineteen eighty two sci fi classic Blade Runner.

Kobe Bryant John Altobelli Kerry Christina Mauser Debbie Francis Sanderson David Beverly center Los Angeles Josh Tiana Alyssa Altobelli Serra Chester Christine Mouser bribery CEO
"mouser" Discussed on NewsRadio KFBK

NewsRadio KFBK

01:40 min | 1 year ago

"mouser" Discussed on NewsRadio KFBK

"I heart radio station news ninety three point one KFBK another passenger who was on board the helicopter that crashed killing Kobe Bryant is being identified family members say thirty eight year old Christina Michelle Mouser boarded the flight and has not been heard from since she was a coach who worked with Kobe Bryant on his daughter's basketball team nine people on board the flight including the forty one year old and be a legend and his thirteen year old daughter the NTSB is launching ago team to investigate the helicopter crash the agency said the investigative unit will arrive in California this evening former Laker star Kareem Abdul Jabbar is mourning the death of Kobe Bryant always seven my most sincere and heartfelt correct and prayers and my thoughts are with you guys Abdul Jabbar posted a video this afternoon after news that Brian was dad in a helicopter crash I'm in Jellico will be ha and a very pleasant good evening to you we have the brake lights coming on in Sacramento eastbound cap city freeway at fifteenth street I'm seeing a multi vehicle pileup in the left shoulder there's debris and all the lines be careful if you're in that area stop and go traffic westbound cap between Camino in American river fulsome still see in that accident he's bound fifty at ease Bidwell street it's a solo vehicle that hit a tree with possible injuries involved it's block in the shoulder traffic on the tens every ten minutes mornings and afternoons Steve forever dues ninety three point one K. for Kerry patchy clouds tonight low forty two to forty six tomorrow animals clouds and sun I sixty one to sixty five mostly cloudy tomorrow night low forty four to forty.

KFBK Kobe Bryant Christina Michelle Mouser NTSB California Kareem Abdul Jabbar Abdul Jabbar Brian Jellico American river Steve Sacramento Kerry
"mouser" Discussed on The Hilarious World of Depression

The Hilarious World of Depression

03:11 min | 1 year ago

"mouser" Discussed on The Hilarious World of Depression

"It uses your brain to make you think that these lies makes sense. It's hard hard work blowing the bullshit whistle on that sometimes and sometimes depressions lies can be pretty creative. My name is Hannah. I live in Seattle donal and my depression likes to come up with lies that we're not in the throes of a depressive episode are ridiculously silly which makes them very easy to recognize now An example a few years ago was unemployed. Going through a really serious medical issue and deeply depressed might version decided that all of my friends that they weren't a secret club dedicated to hating the one day soon they would pull the got from under me and the way they would trip me was by doing nice things for me like bringing me food after surgery and not just take out food. That took a lot of time to make lasagna. brisket that kind of thing and and now. That's pretty hilarious. But at the time I was like Oh yeah that makes total sense. Of course. That's how they're gonNA drink me a more. Recent example is I published writing online online anonymously and some people have said some very nice things about that but my brain has decided that none of these people meant what they said and they all felt sorry for me. Because I'm a terrible terrible writer. And how could I ever think that anything that I wrote was worth reading. which also does it make any sense? Because these people don't know who I am. What has helped is really interrogating those weird lies because depression is in the business of making you feel bad and not making logical sense chance? I have at least one friend who I can go to who will tell me without judgments to not let depression drive the car. Even though it wants the keys very badly ably and the thing that's probably helped the most is cognitive behavioral therapy. It's a lot of work you have to put in the time in the effort but it really really really really helps. Thanks a secret club. A conspiracy. It's all built around this idea that since depression made do you hate yourself others must feel the same way about you. It's the only logical way you're capable of seeing yourself but it's line number nine if if people are being nice and caring toward you there's a very high probability that they like you and care about you because Clinton d diminishes your value you to yourself. It's easy to project that diminish self into other people's secret motives and agenda but it's ally Elissa mouser her. I live in Akron. Ohio Depression told me that I wasn't good not just that I wasn't good enough but that I wasn't good at all as a result I wasn't able to see my own value for a long time. I did things that were harmful to myself because I didn't care about me. Figured it out after realizing they help people and I do good things and then I can choose to do that. My depression just tells me that I'm not good but it's full of Shit like that. You're no good. You're not no good. That is good all right. Let's do one more make an.

depression Elissa mouser Hannah Ohio Depression Seattle writer Clinton Akron
"mouser" Discussed on This Is Only A Test

This Is Only A Test

02:05 min | 1 year ago

"mouser" Discussed on This Is Only A Test

"Mortar com as you find more details about that does interesting might not support. It depends on what what frame rate. Oh. What hurts lots bits? We're not gonna have a full moment of science because shorts here, but to want to call out one is that the solar sail that planetary society had been working on this call Sagan's big dream. It may take flight soon. Great as a payload to what was happy, but launched which was the falcon falcon SpaceX? Falcon heavy did you wash launch? Yeah. This launched from this most recent space x? Well, it was part of the payload. Yeah, I don't know if there's deploy yet haven't done the the goal. But did you watch the launch and yeah. I mean, I hate to say it's routine now I was sad to see the Senate corden quite make it. I mean it's not it's not science fiction when you see the booster God, solely scientific is super signs. I love it watching video in reverse. It's awesome. I my hand over my mouth, just like in anticipation. Yeah. And when it landed the boosters amazing, and the core exploded, they, they rolled with it pretty well. Yeah. Onscreen presenters in livestream. It's happened before. That's four technology news before we jump into our last segment, which will be the VR minute. I wanna thank the other sponsor that makes this podcast possible, and that is mouser, if you ever wonder why your cat seems poor of its toys, so fast cats are natural born predators that one hunt, but today's automatic toys, just move around randomly, but real prey is at random real pray reacts. That's why the guys at Petron IX invented the Mauser a fully autonomous robotic mouse for your cat as peachy students in the electrical engineering department. The university of Illinois. They knew that Mauser had be a robot to actually be interesting for cats. So Mauser comes with a complete suite of sensors and onboard intelligence so can sense and react, your cat. And it's an virement..

Mauser Petron IX Sagan university of Illinois mouser Senate corden
"mouser" Discussed on Download

Download

02:38 min | 2 years ago

"mouser" Discussed on Download

"The most British video ever, which involves a policeman helping Larry the cat get back into number ten Downing Street after he got locked out it happened. During Sky News is live broadcast. The cat was sitting in front of the world famous door where the prime minister of Great Britain lives at number ten Downing Street waiting patiently for someone to be let in. In and somebody the officer guarding the door outside alerted somebody inside, and they then they let the cat in. But Meanwhile, British TV viewers are sitting there thinking, hey, dude, right behind you. There's a cat. There's a cat. They're somebody can let the cat in somebody's gonna let the cat in. And finally, they the security person opens the door the cat goes into number ten Downing Street. It's all fine. What I didn't really realize is Larry the cat is super famous. He is the chief mouser to the cabinet office. He was I think found is a stray. And now he's officially the the Mauser and greeter of the prime minister's residence at ten Downing Street, and although he was brought in by the previous prime Minister, David Cameron. They made it clear that he belonged to ten Downing Street. And so now Theresa May the current prime minister gets to Koha. Cohabitate with Larry the cat. And I if you look at his Wikipedia page, they've got one of those by graphical info boxes on the side that that has a picture of Larry and his title. He's the incumbent chief mouser to the cabinet office preceded by Sybil, and his occupation is mouser. He's about eleven years old born around January two thousand seven his nationality, by the way is British. So Larry the cat. I am delighted that there's an official ten Downing Street cat. It's great with with a very serious photo. Kapadia just to go click through look, he's got a little a little bowtie. Yeah. He's good. Jason as he should. That's the bow ties. The last thing in the minds of the mice before he kills them to them. Oh, boy that took a turn. Anyway, that is it for this episode of download thank you for listening. Thank you to Patrick and Glenn for coming on. And thank you to Steven for being a part of this totally different kind of download episode. Thank you. It was a lot of fun. All right. And we will be back in a week. And until then we will keep watching the headline. So you don't have to thanks for listening. Everybody next week..

mouser prime minister prime Minister cabinet Sky News David Cameron officer Jason Britain Kapadia Theresa Steven Sybil official Patrick Glenn eleven years
"mouser" Discussed on What the Tech

What the Tech

04:12 min | 2 years ago

"mouser" Discussed on What the Tech

"West doesn't work well with touchscreen, and they tried to have touched features. I think this is the first dive into having a touch base, MAC. Yes. Oh, by the way, I was just thinking about this. The apple. In Taganrog toward touchscreens. MAC never made any sense to me, but it just occurred to me because we think about this, you know, on an ipad pro where you're using their smart keyboard, which is basically like a keyboard cover, that kind of origami is around. You can type on the keyboard. That's neat. But when you need to do anything. You have to raise your finger up and touch the screen. You know, if you want, you know this there times when you still have to do this because they don't put a track Pat on it. So ironically, the thing that is unacceptable and MAC, which is a user reaching toward the screen, perfectly acceptable in an ipad. And I don't understand that. I, to me, the MAC will always be what it is. It's what windows is. It's a desktop operating system. It's primarily mouser pointing control, whatever it is and keyboard. Yes, but touch is one of those things. We've learned this over the years when you have it, you'll use it in these situations. The ipad of productivity tool is to screen focus with to touch focused. The MAC is not touched focused enough. I mean, there's a happy medium here, right? You could. You could add a track pad type thing to an ipad pro. Most users would probably not use it most of the time, but when it is there, it would be wonderful for the millions of people who are weaned on traditional productivity focus PC's reverse. Yet most people use a MAC probably wouldn't use touch, doesn't hurt anything, you know, and for the people who do need it would want it is wonderful to have. Yes. So I mean, this is obvious obviously the evolutionary steps that were seeing. I mean, we see it on the windows side and listen. I was one of these people that did not really care for a touch screen, windows laptop. And now you know, once you have it, you know, my HP's touchscreen I tend to use that a lot. I tend to touch around my surface. For example, Reva bunches references in my office, and I always end up using the touchscreen when I was one of these people that was kicking and screaming that I didn't wanna touch screen, laptop. So obviously, this is the next step in for the on the apple side. But this is the next couple years we're talking. We're not talking next year. We're talking three years, four years, maybe five years down the line when everything is kind of working out for them in this in this new, I o Wes Centric MAC OS. That's when they'll leave the processor change that everyone sort of expects it. Should that happen on the low end match? They go to the their own a series chips, which are I'm based if they and my iphone does turn on because she was excited now, please don't. Talk, and you know, maybe that makes more sense than that timeframe. So I like this operating system. I, I've had it for a couple of days now. Obviously I was using a beta, but it feels a lot pilot allow more polish than previous releases. I, you know what I do like have used the dynamic stop. No, it's just the thing where automatically stacks. No, no. So. Backgrounds? Yeah. Yeah, I leave it dark mode and I leave the dark wallpaper on. I, I like the look and I did play with that. I think it's cool perimeter. My dog is going insane for some reason. Sorry, it's all right. Yeah. So I mean, that was that was not too much more. Obviously, we'll talk more in detail on, you know, later on when I tend to use this thing a little bit more and I find more features that absolutely love, but. Nice upgrade, people would max. They're going to be happy and people don't give a crap. So that's that's how it is. So let's let's take a moment. I wanna talk about the Samsung event coming up next couple weeks and the LG event that's coming up. Are we going to little crazy with the amount of cameras are putting on these phones?.

West apple Taganrog Samsung mouser LG HP three years five years four years
"mouser" Discussed on Newsradio 1200 WOAI

Newsradio 1200 WOAI

03:34 min | 2 years ago

"mouser" Discussed on Newsradio 1200 WOAI

"Date up to minute w away. I I mean I had the Jag wagon, last year and. I thought it was awesome I remember how much you? Loved the dodge magnum. Revolvers came out? And saw Dr Dodge magnum with the with the Hemi but this one is just doggone. Ugly and you know it's there are positives and the always look for those I mean the car's got. Quattro system so it's it's quite capable of offer out, of your in a place where there. Is inclement weather I, think it's the, cars intended for those. People who don't. Really wanna make that transition to an issue they won't. The better gas mileage of a vehicle car. But, they need. That extra cargo area their station wagon provides but doggone it I just? Couldn't, drive it pass. Wednesday it's sitting in my driveway and I have touched sense and then the other problem? Is, the price, oh my goodness now this one while equipped always they sent me the. Loaded ones right fifty six thousand dollars and how big is it a four platform It's not. It's not overly comfortable but it's not overly big Robert in Waller Texas? In, the Houston area. Welcome to the car pro show Hello Robert How you doing I'm. Doing great what can I do. For. You Well last year about, a, patriot and it was around March is when I bought it actually I spoke to you before about it because it's. The, one that the clock electric digital, clock, losers time. On it yeah? I remember that. And he says oh that's normal Yeah right Question though is I'm considering leaching. Like, Tacoma Yeah Okay how long how long should I wait because I, still, oh about fifteen on, this not how long should I wait or does it matter before I take it to see if I can trade it in to lease. Mouser I right now Robert right now sixty eight. Thousand A twenty fifteen it. From carmax oak how you bought it used okay Yeah I. Was thinking wow, that's a, lot of miles and short period of time you're a half you know I think I think I would want to know, where you stand right now so that you, don't get a surprise you're you're familiar with carmax if I were you I would take it back to them and. Ask them for free cash offer and see what they'll pay. For it they might pay a little more sense about it from them and if it's in really good condition because tips are hot. Right now across the. Board doesn't matter which which model we're talking about GPS are really. Hot so let's see what it's worth and let's get the pay off and with those two numbers fewer holler back at. Me Next Saturday that'd be great happy. To talk to you the twenty eight teams will be gone by December which is typically the best leasing month of the year so you're. Probably looking at twenty nineteen at that time but if you will give. Me, those two numbers, I, can tell you a whole lot more and then when. You're ready we'll. Get you, over to Fred hats Toyota world and get you hooked up on a fantastic lease again December is a great there's some, deals out there right now twenty eighteen Lisa's, but I really think because of the increase residual values if you can wait till December nothing's going to change with. The value of your Jeep between now and analysts gets wrecked..

magnum Robert carmax Lisa Houston Tacoma Fred hats Toyota Texas fifty six thousand dollars
"mouser" Discussed on The Tech Guy

The Tech Guy

03:32 min | 2 years ago

"mouser" Discussed on The Tech Guy

"Your machine will feel unresponsive. What's happening to you is is a hard crash. So the sound you're hearing is, is garbage data pushed into, here's the. That's like a little windows little. That's all you hear you don't. You're not saying here. No, no, I'm here in this. Yeah, freezes. Okay. I know what's going on. That's another thing. Okay. So. Tell you another thing that's not happening to you which is if sometimes the windows crash garbage data is spewed into the buffer that the sound card uses and it will play it and it sounds like a monster. It's terrible and then everything's dead. That's a hard crash. That's not what's happening to you that did it. Do. Get a message to sing unknown US. So then do that unplug the amounts, plug it back in and then it comes back and then you know, I mean, I've cleaned out the registry. I've reinstalled uninstalled drivers and do you want to hear what it is? Yeah, I know what it is. So as you know, when you plug in a USB device, you hear booed him when you unplug a USB device, you hear that sound. You're making that that machine is making saying, I no longer see your mouse. I lost the mouse that it's been unplugged now. Is it a hardwired mouser a wireless mouse? This is a USB mouse. I mean, I okay. It's a hard wired mouse. So what's happened and this may fix it is unplug it, plug it back in. There's a couple of reasons you could get that. It could be that you've got a hardware issue cable problem when the mouse, for instance, that USB cable that you're plugging in if that's frayed or broken. And loses its connection. Guess what windows is going to go boom and guess what else can have a mouse is gonna stop moving because it lost it. So that's one possibility. Try another mouse, not. I've tried several different mouses. I've tried every every USB port on the machine. And I, I get the same problem now I resorted plugging PS two wheel mouse just to where it's not gonna. Go put them because it's not a USB. Mouse. Do you lose any other USB devices. I don't. Well, I could check that out trying some out, but I haven't. I have only have the mouse. So what we're going through is normal troubleshooting process where you look for things that are easy to test, and for instance, trying other mouse. Okay. So it's not the mouse cable, you're eliminating things every time you do this, you. The other thing, which I would have suggested which is try other ports, some PC's you built it. So you might know this have only one USB channel, even though they have multiple ports, some PC's have multiple USB channels. So that's one thing to look at on the motherboard. Make sure you try both channels. If one channel goes down, the other one might still be up if you've tried all that. All right. We basically eliminated the easiest test now. It's probably a driver issue. There's two possibilities left. One is a bad one, which is a balky motherboard. Maybe the, you know your hardware chip USB controller chip is failing or flaky, or has a cold solder, for instance, you've, are you familiar with that. The idea that it warms up. Yeah. So there's something could be that that's the worst case scenario because that basically means you need a new motherboard. This is this is a PC I didn't built. It's a precision. Okay, seventy five hundred..

mouser
"mouser" Discussed on WTVN

WTVN

02:04 min | 2 years ago

"mouser" Discussed on WTVN

"Once again six pack i'm dave and got a little z top beer drinkers and hell raisers to go along with colin cast door founder and partner of seven son grilling and as as johnny was doing the traffic i thought man rolling roadblock that'd be a great name for a new beer how about that what what are we drinking right now 'cause you kinda got us set up with a couple of beverages so what have we been enjoying in the first part of our interview here so so we're starting out with kind of are really mild easygoing it's a golden l some hop character to it because down real easy it's called assistant manager beer it's our tribute to our favorite mouser resident cat assistant manager cat so he he's got his own beer now and it's quite taste how how do you figure out and i'm sure it's trial and error but the whole hot process how much to add or how much not to add or you know you hear about we use hops from this part of the country how much of a difference does that really make especially the the hops from different areas will so it's a it's a great time to kind of be a beer drinker in the country but it's also great time to be a beer brewer in the country right now there's never been more access to different types of ingredients than there is now we can get these super kinda juicy tropical hops from australia we can get kinda piney dank resonance hops from the pacific northwest there's hundreds of varieties that are out there that that only until recently out of them are even just like the last decade they've kinda come around but it's great you just have this really what what used to be almost like a two or three color palette is now just kinda at endless variations you were talking earlier that you know the seven son is kind of a a tribe of your childhood friends and what point did you guys go from.

colin founder partner johnny assistant manager mouser australia
"mouser" Discussed on WAAM Talk 1600

WAAM Talk 1600

01:57 min | 2 years ago

"mouser" Discussed on WAAM Talk 1600

"Entire rack twenty twos and here's all shotguns and here's modern sporting rifles and and military surplus like you're talking probably a mosinee yeah yeah and and sometimes now you know when it comes to working on certain things like i got a couple of mosey negative got a m forty four and a ninety one thirty and i've cleaned up and and they i love shooting them but for the for the price of them and i don't know about normal parts of aol ability but let's say you needed some funny little spring for mosey meghan it might cost you more to get the spring than to buy another rifle you know the other part of that though is mostly gone mousers grand springfield m one nine zero threes all those kinds of things they are cult rifles you know the guys johnson don't have it or or something but if you needed just something like head spacing or or feeding issues or or something like that i'm sure they could help you but they they have done a lot of things for a lot of people there was another one that i know a guy who and he was very pleased with it i would have to check to make sure that that guy is still there but there is a like a middle belt and six mile i think it is that's that's near redford or something or lavonia and the what the the place is called like shooter services okay.

johnson redford aol
"mouser" Discussed on WBT Charlotte News Talk

WBT Charlotte News Talk

02:17 min | 2 years ago

"mouser" Discussed on WBT Charlotte News Talk

"Contributions could fund an expenditure related to a candidacy i don't want the world to keep hearing from this woman she keeps accusing me of x he says trump i didn't do it lawyer pays the money trump makes several payments giuliani says later well he's not sure it goes exactly toward it doesn't matter the goes exactly toward it or if he knew it went exactly toward it or not it's not dirty money how ironic given that using campaign funds is hush money it was his own money it was michael cohen i to put up the money and apparently trump who eventually paid him in neither case is a campaign money in either case is an in kind contribution when the f e c adopted these regulations he write it specifically rejected a role under which campaign contributions could fund an expenditure related to a candidacy so you see it can't be a direct payment it can't be an in kind payment only people who don't know what they're talking about are trying to turn it into an in kind payment but bradley smith is saying it's an impossibility because you can't pay for it out of campaign cash in the first in the first place and he didn't the f e c was concerned he said that would make a too easy for candidates to use campaign funds for personal benefit so in other words the irony here is if allow mouser right if the slip and fall lawyer pseudo lors with law degrees are right that this is an in kind contribution then what they're arguing is you could have used campaign cash for this as long as you reported and what smith is saying no you can't personal debts for example are related to the campaign if unpaid the candidates reputation might suffer so he saying so if you pay off a personal debt that has to be reported a rolex watch a new suit or a haircut might help a candidate look good on the trail is that an in kind contribution.

giuliani bradley smith mouser michael cohen
"mouser" Discussed on KBOI 670AM

KBOI 670AM

01:52 min | 2 years ago

"mouser" Discussed on KBOI 670AM

"Or if he knew it went exactly tortured or not it's not dirty money how ironic given that using campaign funds is hush money it was his own money it was michael cohen i to put up the money and apparently trump who eventually paid him in neither case is a campaign money in either case is an incline contribution when the f e c adopted these regulations he write it specifically rejected a role under which campaign contributions could fund an expenditure related to a candidacy so you see it can't be a direct payment it can't be an in kind payment only people who don't know what they're talking about are trying to turn it into an in kind payment but bradley smith is saying it's an impossibility because you can't pay for it out of campaign cash in the first in the first place and he didn't the f e c was concerned he said that would make it too easy for candidates to use campaign funds for personal benefit so in other words the irony here is if allow mouser right if the slip and fall lawyer pseudo lawyers law degrees are right that this is an in kind contribution what they're arguing is you could have used campaign cash for this as long as you reported it and what smith is saying no you can't personal debts for example are related to the campaign if unpaid the candidates reputation might suffer so he saying so if you pay off a personal debt that has to be reported a rolex watch a new suit or a haircut might help a candidate look good on the trail is that an in kind contribution.

bradley smith mouser michael cohen
"mouser" Discussed on KARN 102.9

KARN 102.9

02:03 min | 2 years ago

"mouser" Discussed on KARN 102.9

"Money trump makes several payments giuliani says later well he's not sure it goes exactly toward it doesn't matter because exactly toward it or if he knew it went exactly tortured or not it's not dirty money how ironic given that using campaign funds since hush money it was his own money it was michael cohen i who put up the money and apparently trump who eventually paid him in neither case is a campaign money in either case is an in kind contribution when the f e c adopted these regulations he right it specifically rejected a role under which campaign contributions could fund expenditure related to a candidacy so you see it can't be a direct payment it can't be an in kind payment only people who don't know what they're talking about are trying to turn it into an in kind payment but bradley smith is saying it's an impossibility because you can't pay for it out of campaign cash in the first in the first place and he didn't the f e c was concerned he said that would make a too easy for candidates to use campaign funds for personal benefit so in other words the irony here is if allow mouser right if the slip and fall lawyer pseudo lawyers with law degrees are right that this is an in kind contribution what they're arguing is you could have used campaign cash for this as long as you reported it and what smith is saying no you can't personal debts for example are related to the campaign if unpaid the candidates reputation might suffer so he saying so if you pay off a personal debt that has to be reported a rolex watch new suit or a haircut might help a candidate look good on the trail is that an in kind contribution.

giuliani bradley smith mouser michael cohen
"mouser" Discussed on KTRH

KTRH

02:17 min | 2 years ago

"mouser" Discussed on KTRH

"Contributions could find an expenditure related to a candidacy i don't want the world to keep hearing from this woman she keeps accusing me of x he says trump i didn't do it lawyer pays the money trump makes several payments giuliani says later well he's not sure it goes exactly toward it doesn't matter the goes exactly toward it or if he knew it when exactly toward it or not it's not dirty money how ironic given that using campaign funds has hush money it was his own money it was michael cohen i who put up the money and apparently trump who eventually paid him in neither case is a campaign money neither cases at an in kind contribution when the f e c adopted these regulations he write it specifically rejected a rule under which campaign contributions could fund an expenditure related to a candidacy so you see it can't be a direct payment it can't be an in kind payment only people who don't know what they're talking about are trying to turn it into an in kind payment but bradley smith is saying it's an impossibility because you can't pay for it out of campaign cash in the first minute in the first place and he didn't the f e c was concerned he said that would make a too easy for candidates to use campaign funds for personal benefit so in other words the irony here is if allow mouser right if the slip and fall or pseudo lawyers law degrees are right that this is an in kind contribution the what they're arguing is you could have used campaign cash for this long as you reported it and what smith is saying no you can't personal debts for example are related to the campaign of unpaid the candidates reputation might suffer so we sang so if you pay off a personal debt that has to be reported a rolex watch a new suit or a haircut might help a candidate look good on the trail is that an in kind contribution.

giuliani bradley smith mouser michael cohen
"mouser" Discussed on WLS-AM 890

WLS-AM 890

01:47 min | 2 years ago

"mouser" Discussed on WLS-AM 890

"Goes exactly toward it or if he knew it went exactly ordered or not it's not dirty money how ironic given that using campaign funds is hush money it was his oman it was michael cohen i to put up the money and apparently trump who eventually paid him in neither case is a campaign money neither case is it an in kind contribution when the fcc adopt these regulations and he didn't the fcc was concerned he said that would make too easy for candidates to use campaign funds for personal benefit so in other words the irony here is if allow mouser right if the slip and fall lawyer pseudo lawyers with law degrees are right that this is an in kind contribution then what they're arguing is you could have used campaign cash for this long as you reported it and what smith is saying no you can't personal debts for example related to the campaign if unpaid the candidates reputation might suffer so he saying so if you pay off a personal debt that has to be reported a rolex watch a new suit or a haircut might help but kennedy look good on the trail is that an incline contribution.

oman fcc mouser smith michael cohen kennedy
"mouser" Discussed on WAAM Talk 1600

WAAM Talk 1600

01:56 min | 3 years ago

"mouser" Discussed on WAAM Talk 1600

"I remember my mousers to i would have been what let's see fifty five seven years old seven years old an honorary mousketeers whatever they call it back then you had to send some dodo walt disney need send your mouse years and you've got the magazine of course which is really cool i should've saved all that stuff and i also remember as long as we're waxing nostalgic back in the day when we were still in detroit my family we would literally walked to a park which isn't a really crappy neighborhood now you walk through that park nine the shot if not kidnapped but we would walk through a park and all of the adults of course would be sitting there drinking beer wine whatever and they had concerts in the park too cool for school and it was just those were much different times but safer times to that was down in the it's where plymouth road meets grand river area those of you that know detroit plymouth road meets grand river area down don't go that way down there not good walking around in the park so i told you before the break what the republicans could have done to save save their republican offices and that's pretty much what they wanna do they don't i don't think they strategize i would love for a republican to call the show and tell me that i'm wrong in this i mean a serious republican i'm gonna see a bunch of the lincoln day dinners i'm going to be there i'll see if you can tell me then i know many of you listen here but why is it that the republican party can't make the realization that once we took this country back in a majority fashion that we need to now govern and we need to govern from the right not the center not the centreleft we need to govern from the right way right because that is what is it that's what's going to save this country that's where this country started by the way this country did not start in the middle or to the left.

walt disney republican party detroit grand river fifty five seven years seven years
"mouser" Discussed on Sam Roberts Wrestling Podcast

Sam Roberts Wrestling Podcast

01:54 min | 3 years ago

"mouser" Discussed on Sam Roberts Wrestling Podcast

"Fashion a wrestling the all in show is the challenge the cody roads in the young bucks accepted technically from dave mouser said it would couldn't be done with ring of honor on to put on a show in front of ten thousand people it is being funded by the young bucks cody roads apparently there are also mysterious mystery investors hope that turns into a story line although i doubt it will be but they're already talking course kale mega and hang main page in and you know everybody in the elite i'm sure is going to be involved in all in i would imagine a lot of guys new japan are involved i would hope a bunch of guys from the indies you know who knows all in should be the marking of what can happen in pro wrestling outside of wwe and i love that it's being put on by actual wrestlers i just think it's a really special thing and something that would only happen in the time that we are living in so what is the news about it this week it was announced where will be and just as i suspected because honestly i can't remember somebody described on this podcast somebody described pro wrestling tease as like the new nwa in a sense that it's bringing all of the organizations that are not wwe across the world at this point together as a singular organization and i think that's true of course perecent tease has put their their branches into the ground in chicago uh with call cabanne over there too and uh it is now been announced that all in will take place in chicago september first september first in chicago and i am already planning on being there flying out to chicago by myself a ticket i'm not worried about media i'm not worried about covering on that worry about having a role i am simply hoping.

dave mouser japan wwe chicago wrestling