20 Episode results for "Moderna"

Home prices rise 13.3% in March - Midday - Marketplace Minute - May 25, 2021

Marketplace Minute

01:34 min | Last month

Home prices rise 13.3% in March - Midday - Marketplace Minute - May 25, 2021

"Your public market portfolio looks good. But how is your private investment portfolio alumni ventures makes investing highly competitive venture capital deals accessible to millions of accredited investors. Go venture investing dot com to learn more to economic indicators. Are out today well. They're good news or bad depending on how you look at it. I'm nova safa with the marketplace minute. I the case schiller home price index. The latest is for march so a couple of months behind but home prices. No surprise rose and faster than the month before they were up. Thirteen percent compared to march of twenty. Twenty the 'cause all those people looking for bigger homes and not enough of them for sale also the latest reading of consumer confidence. It ticked down three tenths of a point this month. According to the conference board but the think tank calls that essentially unchanged from april when consumer confidence rose sharply the survey says americans assessment of their present situation did improve suggesting. Economic growth is robust in the current quarter. And some definite good news from madonna. It's says it's co vaccine works in kids as young as twelve. It could join visors shot as another option for children. Moderna says it will submit its data to us regulators early next month. I'm nova safa with the marketplace minute. Your public market portfolio looks good. But how is your private investment portfolio alumni ventures makes investing in highly competitive venture capital deals accessible to millions of accredited investors go to venture investing dot com to learn more.

schiller Moderna madonna
Monitor Show 15:00 05-14-2021 15:00

Bloomberg Radio New York - Recording Feed

01:42 min | Last month

Monitor Show 15:00 05-14-2021 15:00

"They don't forget. The johnsons are coming over. I wanna find a rosa. Jill hasn't tried yet. Let's go exploring it total wine. Their prices are ridiculously low. Wondrous election helpful guides always low prices total wine and more markets headlines and breaking news twenty four hours a day at bloomberg dot com the bloomberg business and bird. Quick take. this is a bloomberg business on wall street. That gives us an hour remaining in today's session. The equity market pushing hire a lot of risk appetite given a little bit of positively on the recovery story principally the news yesterday from the cdc of a relaxation in federal guidelines. On wearing masks. Now apparently this policy shift was linked to a new. cdc study on kovic messenger. Aren a vaccine so they were found to be ninety four percent effective. Were looking at a rally right now. In shares of moderna as an example stock is up nearly eight percent right now in the broader market the s. and p. five hundred better by more than one point six percent energy shares leading this advance and they are tracking the price of crude oil. Which is right now. Back above sixty five the barrel. We've got a game now of nearly two and a half percent in the extended session and with today's gain we have basically raised the weekly lost w. p. a. t. I some of this may be tied to weaken today. We have the bloomberg dollar spot index down about three tenths of one percent now in terms of aeko data retail sales last month unchanged that was soft but on the positive side the march reading was upwardly revised to show again.

bloomberg cdc Jill moderna
MUTATIONS MAKING COVID VACCINE INEFFECTIVE?

The Highwire with Del Bigtree

12:00 min | 5 months ago

MUTATIONS MAKING COVID VACCINE INEFFECTIVE?

"Apparently there are variants was shown this past december in the uk. We have several variants. Now we have the uk variant. That was a new variant led to lock down there We have a california variance headlines about that was specific to that region. That's one of the brazilian homegrown as they put it right. One of the first ones we know definitely mutated right here in the united states coming out of california. Track your act. We have one coming from brazil apparently as being told and then there's one in south africa and this one seems to be the one that's concerning a lot of people and the south african one. This was fox news. South african krona virus variant may lower vaccine efficacy escaped plasma therapy so scientists. Now this says in the article that the five. Oh one y point v two very involved nine mutations on the virus spike protein wish the viruses to infect cells this worry scientists because recently developed vaccines and therapeutics target proteins. Raising worries that changes could impact the efficacy of treatments and vaccines now goes on to say. Researchers said the data emphasizes the risk of reinfection and may foreshadow reduce efficacy of current spikes based vaccines. Now we're hearing we're hearing a how. How much reduction. Several fold decrease in reduction. And that's just out the gates right now from the early data one of the articles. This was apparently more donors early data on this gave it a six fold less decreased so the south african results in a six full reduction. Antibodies when confronted with immune system that has received the moderna vaccine and then scientists. Can't they just save percentage. Or you know what i mean. If we're at nine percent where you know twenty percent we still sleep with four score and seven years ago until we get to the language. The rest of us are using. Right is a full times. I mean these types of things still annoying. It's only our lives on the line and we do cares six six six. I don't know but anyway. I digress more folds for ya so hang in there now these are scientists out a rockefeller university in this was a recent study looking at twenty patients and they took the blood from the recovered patients who had tested their antibodies and they tested those antibodies in the virus mutation in a lab and what they found this is from directly from the study. It says among the volunteer plasmas tested. There was a one two three one point. Three two point five and one point one two three fold decrease in neutralizing activity against and there's all the variants there. They tested him combinations. Respectfully we conclude that the plasma neutralizing activity elicited by 'em a vaccination is is variably but significantly less effective against particular mutants in tested panel. Yeah jerry what is so terrifying about this. And even madonna when it said we just talked about this last week or i think it was last week when they talked about. We haven't overcome the issue into potty dependent enhancement which i'm going to keep beating on which they think made simply be an underperforming or a vaccine wearing off if we are only weeks into this and we're already seeing a new variant that drops the power or ability of this vaccine. Then again we may be looking at this antibody dependent enhancement problem. That could lead to the deaths of people that have already been vaccinated. Can't get the vaccine out of themselves and what's really striking to me. Jeffrey is one of the things that i've talked to scientists around the world. They keep saying you know you know though. The corona virus is very unstable virus. Meaning it is mutating. All the time the reason they selected the spike protein is because the spike protein is stable. Right it's stable and yet here. We're hearing in this south african variant that it's the spike protein. That is actually experienced in the mutations. Right now which means that whatever scientists and told me that weren't actually correct right and well. The answer appears to be science. Is now going to chase these mutations. Which seems almost Somewhat of a futile effort. But this is what we're looking at. Now let's take a look at this clip. This is moderna answer to these various as it stands today for the viruses. We're gonna stand still still concern about these new variants which are more transmissible. Madonna is staying ahead of the game. It's important we mean agent and developed potential tools and countermeasures. The best defense is to vaccinate the population to stop the spread and mutation of the virus during announcing that it is working on a booster shot after finding that their vaccine appears to be less effective in countering the south africa variant as a precaution. Moderna says it is now developing a booster vaccine a third shot to target those variants and future mutations booster shot that they're developing is just to be safe. We may not necessarily need that. But they're trying to be prepared for what's to come with on that wants to stay at the forefront of the fight against nineteen just want to be cautious nutball now vitor future and i mean i just think about the opening this show ninety nine point six percent of us at the very worst maybe ninety nine point seven. Four percent of us are only going to have a common cold from this yet. How many of us are throwing ourselves into this circus of medicine where they are guessing in jabbing. And you've got the head of saying we want to stay ahead of it. Of course you do because you to charge for another vaccine. You just turned thirty. Five billion dollar profit into fifty billion dollar profit while people are risking their lives with this experiment for what for the point four percent of the only ones that needed and they're probably the only ones that can't take it given the death we're seeing in nursing homes with everybody receiving the vaccine right and that last part of that clip was stefan cell. He was the ceo of moderna. He's a newly minted billionaire from this corona virus response. I guess we're gonna call it so. Of course he wants for that respect. But some that's what the headlines are showing. Some madera is developing a booster shot. This is a third vaccine and like they said they're hoping this would take care of all the variants but you know what happens when another variant comes from another place i mean. How does that work well if this were targeting the south african variant xactly right. I mean we're now we're talking about three vaccines and we're only a couple of months. What one month. I think into this vaccine program and now as it turns out. We're going to have to make another vaccine for you. Because the last one isn't holding up and and i think about it was crazy. I landed in an airplane coming back from. I was doing some work with legislators up. North dakota the other day and as low as landing. Apparently there was two nurses that knew each other right next to me and one was older said to the other one. Get my second covid. Nineteen vaccine tomorrow and there was only two. I'm doing she said. But i'm waiting till tomorrow night because you know i've heard that second one is really a doozy. Oh yeah i heard that too so the first one really made me nauseous. I thought it was gonna throw up but then eventually it went away. But i did. I've taken to the day after off because you know you're out for at least a day or two and then the person in front of me gets up over the back of the says you know my husband and i had cope. Nineteen and my husband is a firefighter. He had to get the vaccination. Does he said the scene was way worse than suffering the disease itself. And they're like oh. And i think about the raw preparing for what apparently is a sickness. And we've reported on this people getting sick going to hospitals. We're watching the death and the headlines. We're watching nurses collapsed on the floor. Where hearing we've shown the shaking and all of the spasms and issues. That are taking place. And i just think and that's to what happens. Look if you're watching your facebook it's a horror show and that's most of those. Were one shot. We're just about to start seeing the results of two shots now. What happens is three shots and we're only a month then. I would guess two three months down the road. We can be four or five shots in what we do. Know clearly jeffries. Anybody getting involved in this maxine program you must expect you were going to be getting vaccinated with corona virus vaccines all the time all the time. This thing looks worse than the flu. Shot everybody already has to get the flu shot. Every year in the flu hasn't been doing well because people are saying you know what that they made me more sick. And i had never had the flu until i got the damn shot and then the idea that you have to get it over and over again and this thing is an absolute disaster on every front. It doesn't appear to be working doesn't they. All say we can't stop transmission. We're not sure that we'll be able to stop transmission. We're not that stops infection. People are getting sick. It looks like people are dying. Even though medicines doing everything it can to say no. It couldn't possibly be connected because vaccines are the greatest cause of coincidence in the world but now three four vaccines. I mean how many people will line up to get that booster. I wonder after getting sick as a dog for two or three days. And then reading that the other ninety nine point six percent. A bus only had the sniffles when we got it. You're making yourself deadly sick for two or three days. Some of you are dying but the rest of us ninety nine point. Six percent of us are like. Gee that's horrible. I i had a cold just like the firefighter said this vaccine is way worse than the disease and it looks like this direction. They're going so it's not just moderna so pfizer quickly Came out right after moderna made those headlines and said that they're gonna they're gonna follow up with their version of shot so adviser fouls moderna developing vaccine booster. Shot for covid now. Let's talk about timelines in the article. It says pending testing and any regulatory roadblocks roadblocks out of the way. Yup i. that's just there's gonna be slow things down. Potential booster shots could be ready for public within months so then they start talking about now that the really the talking point now is. How fast can we get these things people's arms when they gonna be coming. So these are the headlight the headlines that we're seeing it says. How long will it take to get vaccine boosters for new strains of covid nineteen in the article. I talked to pharmacist. Dr anita gupta from john hopkins university. She says assuming that both modern adviser and other companies will use the same vaccine technology as the renee. This will shorten the approval process likely by half the time or more so unexpired. Mental usage vaccine authorization which sped in the clinical trials. It's still experimental. And now we're speeding. The booster even faster should be interesting to watch. What a mess. What an absolute mess folks. If you're out there if you're one of these people that's received the vaccine you know Prayers with you. I and i and i mean i want to honor the people that have stepped up that see this their duty. I have friends that are doctors on the front line. That said you know if. I'm going to back backstage. Anybody than i should have taken it myself. And i agree. I think that you should if you're on the front line and you're ever going to inject anything thing into any innocent people. You should have it to yourself. I but i can't imagine being in the middle of this i. I don't know how people can go to sleep at night recognizing that there's just this this this dance going on as i said a circus around something. That's now in your body and you can't get it out and how many millions are lining up every day around the world All for the point. Four percent that are at risk mainly that clip. It'd be sure to check out our live broadcasts. Highwire every thursday morning at eleven. Am pacific time. You can watch it on. I tunes and twitter we'll see.

moderna south africa california uk rockefeller university flu fox news Moderna brazil madonna Jeffrey jerry Madonna
Moderna Reports Positive Coronavirus Vaccine Results

WSJ Minute Briefing

01:57 min | 1 year ago

Moderna Reports Positive Coronavirus Vaccine Results

"Technology it's in your pocket your car. Your Business and the Wall Street. Journal's Tech news briefing is tracking all of it from consumer tech to cybersecurity from the giants to the startups every weekday. We bring you the latest stories about the companies and advancements that are changing the way we live and work tech is remaking the world will make sure part of it subscribed to the WSJ tech news briefing from the Wall Street Journal. Wherever you get your podcasts. Here's your midday brief from Monday may eighteenth. I'm a are Waylon for the Wall Street Journal. Drugmaker MODERNA this morning reported encouraging results from the first potential corona virus vaccine to enter human testing. The company says the treatment produced immune responses and some of the healthy volunteers in the study and the shots. Were generally safe and well tolerated. If additional rounds attesting are successful Maderna's vaccine could be ready for emergency use as early as the fall. The news pushed Maderna's shares up twenty three percents in morning trading and by midday the big three US stock indexes where each up about three percent the FBI discovered a link between the Saudi aviation student who killed three people at a Florida Navy base last year in a suspected al Qaeda operative. That's according to a person familiar with the investigation. Authorities made the connection based on information found the gunman's locked iphones in January attorney. General William Bar pressure to apple to help unlock a pair of the gunman's phones we report that the FBI was able to bypass security features on at least one of the phones itself. An Uber says it's cutting three thousand additional jobs and closing more than three dozen offices. Uber's rides business plummeted eighty percent in April and earlier this month. The company said it would eliminate about thirty seven hundred jobs. We more details on these stories and other news of the day at wsj.com and the WS champ.

Wall Street Journal giants Maderna FBI Drugmaker MODERNA wsj.com Waylon US Saudi aviation William Bar Florida Navy attorney apple eighty percent three percent
Moderna's CDO on How Tech Accelerated Vaccine Development

Technovation with Peter High (CIO, CTO, CDO, CXO Interviews)

27:07 min | 2 months ago

Moderna's CDO on How Tech Accelerated Vaccine Development

"Taxation i'm peter. Hi my guess. Today's marcelo dumb. Yanni the chief digital and operational excellence officer at moderna a cambridge massachusetts based biotechnology company. That's been at the forefront of the code beck development and distribution in this rule marcello spoke on both digitisation and process excellence in his interview. We discussed how moderna is using. Messenger are age. Prevent and cure diseases such as covid nineteen aspects of moderna data strategy. And how the company has used data to run the most effective clinical trials possible. We discuss how. Madonna is building a digital environment and how covert accelerated the company's digitisation and lastly we discussed the emerging technologies moderna has used in its digitisation journey the importance of being. Agile in. how you adjust your day to day tactical activity to the strategy that you're building and a variety of other topics you enjoy technical. Please consider reading my book getting to nimble how to transform your company into a digital leader the books available now on amazon or wherever else you buy books as a special offer to our listeners. If you fifty or more books for you and your team. I'd be happy to join you and your team for a group discussion on it to learn more. Write us at info at madison strategy dot com or visit getting to nimble dot com and now for a word from our partner nap tio sales teams have crm systems human resources libertatum tatum systems. What about the cio who needs to evolve from a technology expert to business strategist in this digital first world cio and the cfo counterparts must ensure technology decisions are made to deliver business value. It's easier said than done. That's why app ta the market leader in technology. Business management is committed to helping companies manage plan on ops. Moi's that technology spend after. All champions of change need actionable insights. They can trust. Learn more apt dot com and now onto the interview marcello. Yanni welcome to technician. It's great to speak with you today. Thank you for having me peter. Now it's a pleasure. Well marcello you are the chief digital and operational excellence officer of moderna and moderna is certainly a company that many who are listening. We'll be familiar with given the importance of the company during the pandemic. But i wonder if you could take a quick moment to just give a thumbnail sketches to moderna business. Yeah so so. Madonna was founded the now almost ten years ago and on the promise of messenger army and as a as a medicine. So what messenger irony does. It's in your daily activity. Your body produces probably billions of messenger. Made that goes to the dna and from did the enemy they could use protein and protein. This is what makes your body works. And so what madonna does is we sympathize. This messenger aurigny and send instructions to the cell to produce those proteins to prevent or cure diseases so simple. This is what we do and this can be declined in many many settings a to either prevent ocular diseases so the most the most known one is the vaccine. Because what we do was the vaccine is with produce the protein that exist on the surface of the virus and let your immune system respond to this to those protein and build the date munity against those proteins and by building this unity when the virus come the virus has exactly the same signature because those are protein from the surface of the virus and f. Our immune system is ready to replicate against the buyers. So this is the setting of vaccines but we do as well work on on quality. We were on rare disease. We walk on autoimmune so we have twenty plus programs in at different stages in development at that stage. If i take another example and let's say grab diseases. Diseases they usually. You're missing a either a protein. An enzyme or something is missing in yaw dna. So what we do is sympathize. Missing protein was the code of this gene is missing from the dna and the messenger army and we send them instructs the cells to produce those those proteins or enzymes. That are missing. So that's another example oncology. We work as well on training your immune system against the cancer cells and so we have for example that the personalized cancer vaccine so this is an individual treatment for each person where we look at the The mutation Into cells of of the patient to cancel the dacians size old relations in the dna and we compared to normal cells. And what we do is we build. Messenger are name to mimic those mutations. That are cancer and injected to the cells in the body. So the immune system is getting is reacting against those mutation and therefore since they have the same signature is cancer cells. Your your immune system will react against the cancer cells and hope for the kill the cancer. So so those those are the different. The different areas. Where madonna is is is working and we have different. Couldn't cold trial at different stages. Very interesting. I appreciate that view marcello you've been with the company for nearly six years now and your role as i mentioned before is the chief digital and operational excellence officer unusual title. I must say. And i wonder if he could take a moment. And describe your purview. And maybe the two sides of that if i if i can infer that there is a digital components in an operational excellence component of please talk a bit about What is under your purview So when when we started building madonna. We decided that we need madonna to be data. Centric a data centric company and to be able to build the data centric company to collect data. We need to make sure that your processes build and design in a way where you're acquiring this data in an efficient manner so so this is why you can see the the two aspect of myrow. It's about digitisation process. Excellence all operational accidents so my role is to make sure that we are collecting the right data to make the decision and and those decisions can be to accident our gardening in the research setting. They can be to improve. The quality of our product removing any manual steps are improving at the checks that we need to put in place to improve our products Be efficiency making sure that we have very lean processes so we are running and scaling Uh quickly without the burden of building complex processes behind the scale. So we can we can grow an adjunct and the loss visa can be about cost efficiencies. Because you can you can improve your costs by being Being lean being Having the right data to make the decisions and so menagerie but the company was always on making sure that we get those four areas covered and when we build our processes. We make sure that those processes are digitized from day one rather than being built in a manual fashion and then digitize because when you're looking at your digitisation a you don't want to put paper on last you want to adapt your processes to digital environment from day one because you may build it completely different. Annan i always they example. A of airbnb will over those of those companies. Because what they've done is they didn't take the existing booking system that hotels do. They built a brand new model for digital world. And this is what we try to achieve in a way that although it's very different than In madonna for a biotech for for biotech settings. So that's that's how. I describe my role very interesting. Can you take a quick moment and talk a little bit about the team underneath you. And how they are structured as well. It's an interesting purview. As i mentioned and very well explained as to the rationale behind it. How do people line up underneath you. In terms of their areas of responsibility. Yes so so. The team i festival might team is very diverse. I would say so I have. I have to quad of the team. One part which is the digital team is really focused on the digitisation. Making sure that That we are collecting the data in an appropriate manner unsown. And even when you look at this team. The data component so one component of the team is focusing on each of the functions and and one component of the team is focusing on capabilities. So i take research as an example. We have a dedicated team focused on research damian's on technical developments and their needs on manufacturing end. They are needs and so on but we have as well capabilities that are across all those functions like data science. Ai machine learning we have capability that span across all those functions so so when we work on problems to resolve we have competent team that has capabilities across all the functions and can span across all the functions. So this is one piece. The other pieces around automation. It's the same. It's a capability that we provide to all the functions to make sure that they are operating in an optimal way and day can intervene was their excuse to support the function. So it's brought to go on horizontal at the same time and and Diversity interesting as you mentioned in your description of the the company it is perhaps best known for the work done relative to covid nineteen and the extraordinary pace at which a vaccine was developed and i wonder if he could take a moment and talk a bit about the role that technology digital played in facilitating. What is really an unprecedented pathway towards the development of a vaccine yet. That's interesting because wasn't overnight. What we did when kobe happened. Is we use all the infrastructure that we have already wisdom blazed to support our other clinical trial of course. We focused focused on govan to make sure that we deliver an expeditious timeframe but we used all the technology that we have implemented before. Give you an example. When when our scientists go design the messenger. Arnie for their protein data on wet. Balto that we designed for them. So that's that's a preclinical setting so this one day. The research and they have access to public libraries private libraries. That we bill end they go and designed to have tool set to design that messenger. They have to set the design the proteins and song and when they finished they select the the messenger ornate select the formulation and they push a button. It goes to a central lab at that we have built our norwood facility to produce those messenger. Auditor need instead of going and viper thing in the lab an edge each step of this process. We collect data information. And so and we've been doing this for the past. Let's say five five six years when when we stopped the digitizing heavily company and now that we have this wealth of the we were able to suggest the scientists well Changes may be on on the nuclear died that the usa messenger aurigny based on learning that we had so we have a great makes can suggest some changes and scientists has the last say on to make it easy to produce or accelerate the production cycle time. We have some garth mixed help us at predict the yield on the production side so we have the right volume and dan so all. This data help does build a garden. When covid kane. I would say we use those to deliver the covid a message rodney construct in a very quick manner because we had all the setting in place so we were able to deliver a expeditious. The of course. There's plenty of other activity that we are going on. The manufacturing side on the clinical side and another example acknowledging helped us. A lot is that we had built with our as he are. Cro so this is is. The company that are helping us was the clinical trials. The sites were while we had the house volunteer comings and so on and we we have been building integration into assistance so we can collect the data and when we started the clinical trials on it. We were able to get this data real time to tell us what's happening on each of the sites and we this date that was public data to make sure that we have the right setting from a diversity from a critical Adrift a critical Patients and so on so we have been able realtime digest our clinical trial to focus on what type of patients we need How many elderly we have in our hotel diversity we have and so on so we just the clinical trial to to match exactly the population that needs to have those clinical trials. So this this was an accident ration- and it was extremely helpful to the clinic of the team to have all those tool sets available to so that those are examples of how are building digital environment. That very interesting. And and what would you suggest. Marcello are the learnings for the future shirley Without the focus of the entire world. The on a single the pandemic as was the case this time that focused the the focus of the governments the eye the eyes of of essentially the world's population In some ways provided that much more of a reason for this level of focus are their learnings from this though that can be taken to other vaccines that will be created. Even those that are not addressing a pandemic that's impact the entire world in the same way yeah Actually i think everything that is. I've spoken to the clinical trials. I think we saw even now writing mall on the digitization the violent reconnecting. This as well to i would say now that we have a commercial setting that we have data that is coming from the commercial food. We have. Millions of people acceded Vaccine so the next frontier for us as well. How can Now collecting data extremely to help us. A was was the existing vaccine by as well as the development of the new The new drugs that walking on all vaccine that we are working. And this is this. This has allowed you. Jackson is and how how we build the digital biotech. And how we bid for the future are was Was digital so so yes big learning here and i think the other piece that go well helped us at madonna is expedited scaling up because we had to build scale up to support the external manufacturing as we often was lonzo in in europe to produce for international setting. We we augmented our capacity in the us as well Was long for the us market so we had to scale up all the supply chain to be able to support old those Those environments we had to scale up manufacturing. We had to scale up. Get all the quality system so we built environment and we were able to do on the scale up because we had the foundation in place because we had the integration in place Pyramid i always share was whoever discuss about digital and our strategy discrimi- stopped. We have built in drought. Everything that we have built in. Madonna is the cloud because this provide us the flexibility adaptability to move quickly. Then we are very very strict on integration. Make sure that we have system of records that collect the data that awfully integrated so we are not replicating buildings silos. A those silos get efficiencies and you can see them big settings they lead to people translating manual information between different organization and so on so. We wanted to avoid all this then. We re focused on is not connecting the instrumentation to the information systems. Collect the data and standoff transcribing the data manually from from the instrument to them formation system. And then we looked at automation and automation a week when our processes were mature. Ready when this is where will seek operational excellence and comes into play. When our processes are mature and and you believe that law commission can be implemented. This is where we start to putting him automation and they may start them in island for the nation and then you can make those island full automation and songs. So so those approaches. This is how how built and then top of this when you have all the simplest you have a wealth of data that you can use and whole early. Grail of course is a machine learning but even dead space in a machine. Learning we are very pragmatic within go to boil the ocean. We looked at very very specific problems that we needed to saul and wear some ai techniques could help and we looked at machine learning. We've looked at beijing. Statistics or will based out gore makes sense so on so it wasn't one set was everything and the lost piece i would say is that we decided that if tools exist in the market will buy them will integrate them if they didn't exist and we needed to focus on end to end process digitisation. We will build. What's missing so we have a software engineering teams on. That can help us do this. So i hope this on so the question but this those learnings and the future and how we see the digitisation ongoing and madame. that's fantastic. Yes thank you for that overview marcello. I wondered it. Are there other leadership lessons. That you've learned through this most unusual time of the past year In terms of i mean no doubt of course many of you are colleagues still work in offices. They have to in order to do the work that they do. I would imagine that a good portion of your team has been working from home. And and i imagine that that's that's at a rate that was higher than it was i. I use that as one of the possible areas. One of the changes that have been forced upon so many of us I wonder if there are other kinds of lessons. That you've learned as a result of these changes that will impact how you think about the building of teams where they are in how they interact with i. I will say that from leaderships debate. Boggy was about strategy. That strategy is not set in stone. And you need to adjust to the conditions. A number on around you and this is what cova told us is. We came into a twenty twenty was different completely different things than where we ended. Twenty twenty and different completely different strategy as we had to adjust and adapt to. What's what's happening around us. And the markets and the pandemic. Its own so that was a big gardening and the learning is how you drive the team and then changing of one. I think i think the biggest army For me was how close you need the state to the teeing a an indirect and not to be a an not to be in control but to make sure that we are all aligned and adjusting in real time to the changes that are occurring around us. I think this is the biggest. Broadening is being ajar. In how how you adapt and adjust your your database As effective activity and adjusted to the strategy. That you're building so i. I wasn't dutch in the regular basis was might the even maybe two or three minutes a day just to talk out some small activities that we needed to stop usually when office. You do this on the hallway. You go to the desk. You have two minutes on bus station. So we had to adjust this during the during the spend so and i i imagine why not the only one in debts face many companies at the than use video conferencing tool said that they had available to. Yeah i wanted to also ask you marcello you are a board level technology. Executive view about two years ago joined the board of similarity in cambridge massachusetts. This is a growing group though. Still a fairly exclusive one digital and technology executives joining the boards of companies and. I wonder if you could take a moment and talk a bit about your pathway to getting to board membership and By extension recommendations would offer to others who would wish to walk in your footsteps yes so sadat is a very interesting company. And it's it's it's a new ended. Spoke of the flagship a flagship Companies which which is where madonna madonna was started and celebrity is at a different gear between technology and and biology. I would say because of what what they do. Is they lose. Lots of a machine. Learning modeling to predict cell behavior and asfaw in addition to the biotech bought membership. They wanted someone that comes from the digital environment in novato one and by down the standard the biotech industry. My background is not in biotech. I stopped when as a software engineer buildings for the aerospace industry so most of the high tech industry. But i think i think what they were looking for is is this makes of how technology how this machine running a science is hoping the license and and a combination of two of the two and how they can be to build companies like sadat my advice his digitisation at the science. Those are going to play key roles in the future. If you look at the past. Twenty years dave lucien of the talk at the top companies in the world dwell may twenty years ago was more the federal industry today. It's small debate. Industry grew the amazon of the world. And this is what's shaping probably the changes that you've seen in science and biotech. While i wanted to close by asking you about trends we've talked about a few of them that are rising in that you are taking advantage of. But what other trends marcello you look to the future particularly excite you. Yeah so so of goals Early days of ai machine darning was all all the pros and cons so fusing them in different settings and so on another uptrend. That i'm looking at as ended team is looking at this. Maybe quantum computing because now was the wealth of data on the sets of data are available and the power off of this data. You need very powerful computers to help you While do the analysis in less time in song so this is a next frontier that are exploring just to see if if it can help us at if it help us how we can use it to improve and hopefully find new drugs. That can help improve. The world dwelt patients wonderful. Well marcello dominy so much for taking time with me today and explaining a bit about the practices that you and your team have have implemented especially in this the most unusual past twelve months and the remarkable changes that you've been a part of and helped drive. It's been a fantastic conversation. Thank you thank you peter for having thank you. Thanks for tuning in. Please join us on thursday. As i discussed the role strategy and driving growth and innovation with shush precaut- the chief information and chief product officer of the washington post in chilton mehta chief information officer in head of digital technology and innovation at wells fargo.

moderna marcello madonna cancer Yanni Madonna madison strategy tatum systems moderna business messenger army peter Balto marcelo covid kane Moi cio cambridge airbnb massachusetts lonzo
EBEN BROWN Q&A

KILF Morning New Podcast

04:53 min | 6 months ago

EBEN BROWN Q&A

"The head of the food and drug administration says the fda is moving quickly to authorize a second covid nineteen vaccine key advisory panel endorsed the vaccine produced by moderna at mid weekender expecting the the final approval. I guess today fox's eban brown covering the effort. Good morning faulk a good morning. Good morning fox gets there. So is this going to happen today. You think yes. I do believe it The what what is known as the emergency use authorization will come from. Fda today We saw that last week with pfizer. The the advisory committee voted pretty much in favor of doing it. for pfizer's vaccine and then about a day later came the way yesterday's The same committee meeting yesterday. this time. voted twenty with one abstention To recommend the moderna vaccine so that was a better outcome than what the pfizer vaccine vote was and so i suspect Fda's emergency use authorization. Will will come today. Which will trigger. Operation warp speed distribution of the vaccine. Probably starting in a couple of days. So is this one ready to go. The fires are one was. I mean we kept hearing the you know. The visor was being shipped from overseas. And it was being distributed at you know different centers across the country and it was ready to go and we haven't heard much about that for the moderna vaccine during the as well. Moderna has already been producing vaccine. We have six million or just about six million doses sitting ready for distribution And so remember. The goal of four operation warp speed is to vaccinate twenty million americans By the end of the year. That's in a week and a half or something or two weeks. I guess right I'm getting my math right so The millions of doses. That already went out. And moore's coming pfizer than six million of moderna and more will come if that looks like they'll be able to make that goal. I'm curious about the language we're always hearing this is called the emergency use authorizations so they can get it out quickly will the term emergency use eventually be removed and the vaccine is just a given final stamp of approval and would that need to meet some higher standard Not necessarily a higher standard but there would need to be more data confirming the same standard More data is needed before full-throated approval is given what the emergency use authorization allows the fda to do is to say we have a lot of data and the data is very good. That I would suggest that the vaccine is a effective be not dangerous overwhelmingly And see there is a true immediate. Need well the corona virus does dictate the those three conditions. So i that's good enough for the What they call the emergency use authorization that there there are. There is data suggest that it is effective and that it is safe What but it doesn't have the full amount of data which we couldn't have because we we didn't test for that long. We tested where now we they tested Tens of thousands of people In the phase. Three trials But they still would need more data for a for a full approval The thing is as they give this vaccine out the data that they can Gets to factor into the file here so in a few months the fda could theoretically grant The more permanent approval. Is this going to become more of the norm for future vaccines and future medications. That it's going to move along a lot quicker than it has because of this whole thing you know. I think that would be wonderful if it did The problem is is is what what normally takes years and years and years for vaccines to be developed. isn't a funding matter. Much of the The the efforts to obtain new vaccines are spent writing grant proposals and trying to recruit researchers and trying to conduct studies. That you can only maybe do hundred test cases at a time. Because that's all you can afford to do based on what money you've been able to raise We eliminated that process by dumping in billions of dollars of taxpayer. Money to make all of this happened. That's what paid for the researchers and paid to be able to do a phase three trials with thirty thousand people all at once I don't know if we'll see that for every Every vaccine that is needed out there because it may not rise to the level that corona virus has with this pandemic right. Evan thank you very much. We appreciate the information. You have a good week weekend. You too all right. There's ebony brown with fox news.

fda pfizer eban brown fox moderna faulk Moderna moore Evan fox news
Monitor Show 10:00 01-25-2021 10:00

Bloomberg Radio New York - Recording Feed

01:42 min | 5 months ago

Monitor Show 10:00 01-25-2021 10:00

"Slack is a new way to communicate with your team messaging. That's faster better. Organized and more secure conversations happen in channels that are easy to create. Join answer try it for free at slack dot com slack. Where work happens how you view the volatility in the marketplace here we have a completely different climate strategy of these across the board across industries. China short their balance sheets very very disturbing dynamics at work breaking market news and insight from bloomberg experts dollar politics i think is a lot of its rhetoric of all the dislocation. There's always relative value trades that you could be doing how on home prices go third. The i think that is really speaking everyone. These bloomberg markets with vonnie quinn and polls reading on bloomberg radio good monday morning from the bloomberg interactive brokers studio in new york city and points beyond. And i'm talking really beyond today to our worldwide audience coming up. We're gonna have the ceo of moderna stefan band so he's going to sit down with alex steele guy. Johnson bloomberg television will bring that for and just moments. I'm joined today by matthew miller from earlier. We're getting paul agreed to join to join you. We're getting markets. Hit hard today down more than one percent pretty much across the board. The us open looks a lot better. But i think the interesting thing that everyone everyone's focused on is the vaccine rollout and i thought it was fascinating that fao she said. He's worried about delaying a second dose. Exactly right mad. We'll have more on that coming up right now. The ceo of moderna stefan bound so we welcome now bloomberg television viewers and radio listeners. Joining us is stefan. sell the madonna. Ceo's different thanks for taking the time to join us today you've published.

bloomberg vonnie quinn bloomberg radio good bloomberg interactive brokers moderna stefan alex steele Johnson bloomberg matthew miller China new york city moderna stefan paul fao us stefan Ceo
U.S. Unemployment Rate Ticks Down to 6.7%

WSJ Minute Briefing

01:36 min | 7 months ago

U.S. Unemployment Rate Ticks Down to 6.7%

"This episode is sponsored by. Sap your business and sap solutions together. We got this. Here's your midday brief for friday. December fourth i'm jr waylon for the wall street journal. Us employers added two hundred and forty five thousand jobs in november and the nation's unemployment rate fell to six point seven percent but that's also partly due to the fact that fewer americans were seeking work while the labor market has now regained twelve million of the twenty two million jobs lost at the start of the pandemic november's reports suggests the labor market recovery is losing steam amid a surge in coronavirus cases and new business restrictions. Wall street saw the jobs. Report is a possible catalysts for more fiscal stimulus by mid day. The big three. Us indexes for each up more than half percent in as cove nineteen infections deaths in hospitalizations in the us reached record highs drugmaker. Moderna says it could have twenty million doses of its vaccine available for the us this month pending fda authorization. The vaccine requires two doses per person for weeks apart. Maderno also says it can provide eighty five million to one hundred million doses for the us during the first quarter of next year. We'll have a lot more coverage of the day's news on the wsj's what's news. Podcast you can add to your playlist on your smart speaker or listen and subscribe wherever you get your podcasts. Has twenty twenty disrupted your business and how you reach customers. Sap customer experience provides scalable ecommerce solutions. That help you react quickly to changing business. Needs and deliver on customer expectations whenever wherever learn more at sap dot com slash c x together.

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Moderna Tests Covid-19 Shot in Young Children

WSJ Minute Briefing

01:32 min | 3 months ago

Moderna Tests Covid-19 Shot in Young Children

"Edward jones it's time for investing to feel individual learn more at edward jones dot com slash. Advice here's your mid-day brief for tuesday march sixteenth. I'm jr waylon for the wall street journal. Drugmaker moderna has begun studying. Its covid nineteen vaccine in young children ages. Six months to eleven years in an effort to widen the vaccination campaign. The company did not indicate when test results will be available last year. Moderna launched clinical tests of its vaccine and adolescence ages. Twelve years older. Those results are still pending. Meanwhile european union health officials say the benefits of astrazeneca's covid nineteen vaccine outweigh the risks. The statement comes after several countries in the region temporarily halted use of the shot over blood clot concerns. The european medicines agency said today at sees no indication so far. The vaccine caused a number of blood clotting incidents and the commerce department says. Us retail sales fell three percent in february. The decline follows strong january's sales that were fueled by stimulus payments to households and other impacts from december's covid nineteen relief package. February's typically a quiet month for retail sales as stores gear up for the spring selling season. We'll have a lot more coverage of the day's news on the wsj's what's news podcast. You can add to your playlist on your smart speaker or listen and subscribe wherever you get your podcasts lately. It's been hard to think about the future but at edward jones. We want you to get back to drafting dreams and building plans for tomorrow. Learn more at edward jones dot com slash advice.

jr waylon Drugmaker moderna Meanwhile european union edward jones Edward jones the wall street journal Moderna astrazeneca european medicines agency commerce department Us
Vaccine Wars | Warp Speed | 4

Business Wars

31:42 min | 2 months ago

Vaccine Wars | Warp Speed | 4

"Business is battle on business wars. We learn what it takes to win by looking closely at ambitious battles like the one in our latest series vaccine wars and our new book. The art of business wars gets to the very heart of each conflict. Unearthing all the valuable lessons go to wondering dot com slash. The art of business wars to order your copy now join one replaced to listen to business wars one week early at ad free in the wondering app. Download the wondering in your apple or google. Play mobile app store. Today may eleventh twenty twenty covid. Nineteen is devastating. The united states. Four million infections seventy five thousand deaths twenty million people out of work outside hospitals bodies pile up in refrigerated trailers as morgues overflow and on the streets protesters real against lockdown measures but at the department of health and human services in washington. Dc a counterstrike is in the works in a conference room. Monsef slowly watches as the room fills up with federal officials. Political advisors and army generals a retired drug industry executive whose career was born from tragedy while growing up in morocco. His six month old sister died from whooping cough with better access to vaccine. She could have been saved slough. We went on to turn the pharmaceutical giant glaxosmithkline into the world's top vaccine maker. Now he's about to get a new mission. White house officials starts meeting mr slowly. How much of you been told just that. You want to run something like the manhattan project for the kobe. Nineteen vaccine yes. We want to deploy the federal government's full resources to make a vaccine happen by the end of the year. You will be the chief advisor and lead on the science and general purna here will handle logistics. We're calling it. Operation warp speed warp speed a political adviser response from trek engage warp. Drive mister sulu. Look i don't care what it's called. I just wanna save lives but you need speed and safety a vaccine. No one trusts as useless. The fda's vaccine chief interjects. They decide what drugs can and can't be used in the. Us fda won't be easing its requirements on my watch. The vaccine still need to undergo full clinical trials but we could save time if drug companies start producing doses while trials are underway slowly shakes his head. Drug companies won't mass produce vaccines. That are still in trials. It's too risky. If the vaccine failed in trials and that's not unusual every dose would have to be discarded. They'd lose hundreds of millions of dollars. That's why operation warp speed will supply ten billion dollars to cover. The industry's costs by doses. Build factories secure supplies do whatever it takes to get viable vaccine as fast as possible. Slowly smiles with the us government paying the bills in pre ordering doses. Drug companies won't need to fred about the financial risks okay. I'm in but only if science sets the timetable here not the presidential election. If there's any undue political interference. I will quit understood. There will be no interference. Four days later in the white house rose garden sloughing operation warp speeds newly appointed chief advisor join president trump before the cameras. Today i wanna update you on the next stage of this momentous medical initiative. It's called operation warp speed. That means big. It means fast a massive scientific industrial and logistical endeavor. Unlike anything our country has seen since the manhattan project backed by billions and with the full logistical might of the federal government at its disposal. Operation warp speed is about to turbo charge the vaccine race but with an election looming the vaccine makers are about to get caught in the political crossfire. If you're working around the clock to build your dream e commerce business you need an e commerce marketing platform that works just as hard as you do. That means you need clavijo with cleo you'll delight customers and drive revenue at the same time with personalized email. An sms marketing campaigns. That you can design and send in minutes plus building. A marketing campaign is just a drag and drop away. You can get started with your first campaign in under an hour to get started with a free trial of flavio. Visit klay the video. Dot com slash. Listen that's k. L. a. v. i. y. o. dot com slash. Listen when you're looking for a new home you want to make sure it meets your needs. Can you work in that office. Can your family cook together in that kitchen. You have to know the house fit and with rocket mortgage. You can make sure your financing works for you to with rocket mortgage. You can see your loan options. Closing costs tax estimates and more online in real time to get the full picture before anything is finalized. That means you can plan with certainty knowing you have a mortgage solution that works for you and your family visit rocket mortgage dot com slash business wars. Because when you need a mortgage that fits your life. Rocket can call for cost information and conditions equal housing lender licensed in all fifty states in mls consumeraccess dot org number thirty thirty from wondering. I'm david brown. And this is business wars. On the last episode cove it was declared a global pandemic. Big pharma joined the vaccine race and moderna became the first company to get. Its jab into human trials. Now the entire world is looking to the vaccine makers to save the day but for that to happen. The drug companies must pull off one of the greatest scientific and industrial feats in human history. They must show their vaccines are safe. And effective assembled vast global supply chains and get factories. Ready to produce billions of doses. All in record time. This is episode four warp speed. It's july second. Twenty twenty and pfizer top executives or on another video call on the screen. They get a close up of manufacturing chief. Mike mcdermott's pink shirt. I just need to move the camera. There mcdermott away from the camera to reveal what looks like an expensive beer cooler on his office floor. It's his team's latest creation. This box stores up to five thousand vaccine doses and it can keep the vaccine at minus ninety four degrees fahrenheit for up to ten days the team of executives smile back at like moderna visor. Biotechs vaccine needs ultra cold storage and until now. That's posed a major challenge. Few places have super cold. Freezers and cold. Storage transport is in short supply. This custom made box goes a long way to solving the problem. But there's more mcdermott taps on an electronic device inside the box. This device constantly reports back to us on the location temperature and condition of the box and the temperature rises. Or if there's a severe jolt we get an alert. It means we can make sure our doses arrived safely. The execs applaud. Mcdermott beans with pride. But then he glances over at ceo. Albert morla. He's not clapping. He's frowning leans forward what the hell is. Cvs going to do with five thousand doses. This box is only good for hospitals local pharmacies and doctors offices. Don't need that. Kind of volume. Give me boxes and carry twenty five miles per shipment mcdermott's shoulders sag. Nothing ever seems to satisfy his boss but boola believes people underestimate what they can achieve and with the pandemic to stop. He wants everybody on his team doing their absolute best. But there's another reason. Borlase agitated financial one some data from both in july twenty first twenty twenty and the front runners in the vaccine race or under the congressional microscope on a video call. Representatives are about to quiz key executives from pfizer moderna astrazeneca and johnson and johnson. The hearing opens with the drug companies updating the politicians on their progress so far astrazeneca's man is feeling cautiously optimistic. The vaccine it's working on with oxford university is now leading the pack today. We announced that they not phase one two trial which showed a robust immune response in all the participants tested. Hope the results from our late stage. Trials plans involving the thousand volunteers will be available by this full. Still we're gonna adviser aren't far behind. They reveal that they're vaccines. We'll start late stage trials before the week is out with results also available in the fall but it's a different story at johnson and johnson. It won't start. Its first human trials until september. But there's a reason it's hanging back while the others are creating to dose vaccines. Johnson and johnson spent extra time in the lab designing single shot vaccine. That delay won't cross the finish line until the beginning of twenty twenty one at the earliest. But it's hoping it's dose will make up for lost time by getting people fully vaccinated faster following the updates members of congress. Have some serious questions after all more than ten billion dollars of taxpayers. Money is being spent to make these vaccines happen. Could you tell y you believe it's possible ring. A safe and effective covid. Nineteen vaccine to market in twelve to eighteen months when currently the fast is vaccine to be developed as was mumps in that took four years. Visors chief business officer. John young responds in order to reduce the normal time team such development program. We're doing steps in parallel rather than sequentially which requires more capital to be deployed at risk is the only way to cut significant time from the development program while maintaining safety is a key priority next democrat member. Jan schakowsky challenges the drug companies on price. We'll you sell your vaccine at cost and relied on-track transparency. So that we can verify if you aren't making a profit snow dr hub. I to respond is moderna. President stephen hogue nearly a billion dollars from the us government to fund trials of its vaccine. But it's not passing up. The potential for profit are. We will not sell the cost. Will we will not tell it a cost. No ma'am little not celebrate next astrazeneca operation warp speed is paid one billion dollars for three hundred million doses of its as yet unproven vaccine. Do the agreement we have with thought of for the three hundred. We're filling of note. Quit johnson and johnson's tar. It got half a billion dollars from the government toward the development of its vaccine. Yes we will be providing vaccine for profit price during the emergency but not everyone's going on the government payroll mr young trump wiser. Your company has rejected tax ear funding partner vaccine. I'm concerned that you will make that. You made this decision to be able to. Price scout will pfizer commit to avoid herbal vaccine pricing that we didn't accept the federal government funding solely for the reason that we wanted to be able to move as quickly as possible there being candidate and refusing the government's free lunch is a risky. Move on visors. Part if its vaccine fails in trials the company will lose at least a billion dollars but visor doesn't want to risk getting slow down by having the government over its shoulder constantly and demanding changes. It also doesn't wanna get ensnared by politics. by refusing. operation warp speeds investment. No politician can claim the government has a right to tell pfizer what to do or how to price its vaccine but that doesn't mean it won't sell doses to the government in advance and just twenty four hours after the congressional hearing visor. Does exactly that big news of course is that pfizer has signed a deal with the us government to provide one hundred million doses of a covid nineteen vaccine once. It's approved visor is charging the government. Twenty dollars a dose. That's a two billion dollar. Bill for operation warp speed. The price per dose is in the same. Ballpark is an annual flu vaccine. But far more than the three to four dollars astrazeneca's charging for its kovic shots. The strategies of the front runners are now clear. Astrazeneca's selling a two-shot vaccine at cost doesn't need super cold storage and wants to get it to the public fast johnson and johnson's also selling it cost but taking longer for its rollout. It's betting that the ease of a one shot vaccine will make their products worth the wait moderna adviser however want their vaccines to boost their bottom lines. While maderna's using taxpayer funding to scale up fast visor wants to keep the state at arm's length but as the most financially exposed of the front runners visor must now exceed expectations. A july twenty fourth. Two thousand twenty in his home office in kloster. New jersey visors exhausted manufacturing chief. Mike mcdermott logs into the latest executive team meeting as he connects he sees everyone smiling. Sorry i'm late. what did i miss. Visor ceo albert berlow. Grins by on tech has picked the vaccine. Biontech is the german company. That's designing the pfizer vaccine for weeks now. Biontech scientists have been hemming in hauling about which version of their vaccine to put into large scale trials. They've narrowed it down to two candidates. I produces a strong immune response but also causes. More short lived fevers and chills. The second version triggers fewer reactions but produces a weaker. Immune response requires a larger dose. Scientists decided to wait for more data before making a final decision. Now that data's arrived. Mcdermott feels relief washing over him at the news. That biontech finally made its decision hallelujah. The uncertainty has been keeping mcdermott up at night. The difference in the dose sizes of the two versions has major implications for manufacturing. But waiting for biotechs decision. Before ramping up. Its supply chain. Wasn't an option gift. Visor waited it wouldn't have factories ready to make vaccines by the fall. Mcdermott had to make a call without knowing which vaccine would go into production so he took a guess and told his people to prepare the factories to produce the smaller dose version of the vaccine. He's gambled weeks of work in tens of millions of dollars on that assumption. If his bed is wrong visor will have to spend millions more reorganizing. The factories visor. Ceo birla adjusts his glasses and shares the news with mcdermott very close. But biontech selected the large dose version mcdermott's heart sinks as the team chitchat about this milestone. He does some back of the napkin. Math tallying up the cost of his bad bet. It's not good. The executive stop talking. Birla narrows his eyes. You okay mic. no no. I'm not okay. I thought the other version would win out. We're going to miss the production target. Big time could we maybe dial things back say eighty million doses by the end of this year instead of one hundred. Birla frowns no. We can't people are dying. I want one hundred million doses by year end. Find a way mc dermott slumps in his chair now. He has to rework a global supply chain involving forty sites and more than two hundred suppliers. The logistics nightmare and the cost is enormous. Some of the machines needed to help produce. This vaccine cost as much as two hundred million dollars. There's no point arguing. The company's pushed to deliver a vaccine has an almost unstoppable momentum. Factories are being set up. Suppliers are already producing huge quantities of everything for medical glass to cold storage boxes to the chemicals needed to produce vaccine there while it means more work for mcdermott. By on tech's decision means visor finally knows which version of the vaccine to put into its late stage trials the following day the first of forty three thousand volunteers get their initial shot. It's the trial that will make or break visors vaccine but modern is not letting visor get too far ahead. Just forty eight hours. After pfizer's starts hits late stage trial moderna follow suit. Good evening and thank you for joining us. We want to begin tonight with a huge leap forward in the development of a vaccine against corona virus. Volunteers all across the country including a member of our own. Cbs news family began getting shots today. As part of the final phase of testing for an experimental vaccine being developed by the nih and the drug company madonna. The vaccine race is now too. Close to call. Visors ahead of moderna. Mere hours astrazeneca's lead meanwhile is shrinking fast and the fda is about to move the goalposts. It's demanding the trials involve more people than usual and that's called astra zeneca by surprise it's scrambling to launch an additional. Us trial before it falls behind now. Even the smallest setback could make all the difference depending on where you live. And what's available to you. You might not have convenient access to high quality meat and even if you do you might have experienced sticker shock when you've gone to buy free range organic chicken or wild caught salmon at the grocery store but today's sponsor and one of my favorites butcher box believes everyone deserves high quality humanely sourced meat when you order with butcher box. 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It's great knowing your eating one hundred percent grass fed beef free range. Organic chicken pork raised crate free. I think it helps us eat healthier and smarter and you can enjoy this to try it for yourself. Remember for a limited time. Butcher boxes offering new members of free essentials bundle in their first box. That's three pounds of chicken breast two pounds of pork chops and two pounds of ground. Beef offer free in your first box. Just butcher box dot com slash. W that's butcher box dot com slash b w to get a free essentials. Bundle your first box. We get support from amazon business. Is there something stopping you from achieving your business goals is at time money or both well at amazon business help with access to millions of discounted supplies and tools to streamline operations. Amazon business is helping companies governments and nonprofits of all sizes plan for. What's next when you simplify purchasing your business goals become a lot more attainable. Amazon business shape buying visit amazon business dot com slash be w to learn more august twenty fifth twenty twenty operation warp speed boss. Monsef slough is on a call with modern. Ceo stefan sell and. He's about to ruin bone cells. Day stefan you need to slow the recruitment of volunteers for your trial. And so blinks in shock. Why why. why would we do that for the past month. Madonna's been moving at breakneck speed to recruit volunteers because the only way to accelerate the trial like every final stage. Vaccine trial during a study has strict rules. It must follow. One of those rules concerns the independent committee that controls the data from the trial. It won't release any results to modern until a pre agreed and statistically meaningful number of participants have caught cova. And until it gets that data moderna can't seek emergency approval from the fda so during and the other vaccine makers are trying to speed things up by recruiting more volunteers more people in the trial. The greater the likelihood that enough of them or catch cove it to trigger the release of data to moderna but now operation warp speed once moderna to ease up on the gas. If we go slower more people will die slough scowls. He's plenty aware of what's at stake. One hundred sixty thousand americans are dead already. The death toll is rising at the rate of a nine eleven attack. Every two days you need to focus on getting more black and hispanic volunteers. They're under represented could set us back weeks. How many more people of color will die during that time. Black and hispanic. Americans are far more likely to die or get seriously ill from kobe than other ethnic route. All the more reason to go faster we owe these communities. Transparent thorough process no shortcuts. We also need to consider public image image. What is this politics are scient-. These aren't ordinary trials. The world is watching. Anti vaxxers are out there spreading lies and stoking fear. We need to assure people that vaccines are safe. Vaccine that gets left on the shelf as useless. We'll we'll help you with recruitment. But if you don't fix this your vaccine might not get. Fda approval well doing hispan- sale hangs up. He knows moderna shot at creating. The first vaccine approved for use in the western world is over beating the world's drug giants across the line. Even by a few days would have been a massive coup for a company. That's never gotten a product onto the market before maderna's recruitment drive enabled it to push ahead of astra zeneca and stay neck and neck with pfizer. But now the races visors to lose and it's on track to complete. Its trial in october but slowly. Isn't the only one worried that the herculean efforts to deliver vaccines to the market could be undermined by public distrust. It's early september twenty twenty and over southern germany. One advisors executive jets soars through the skies towards vienna. Inside are the to. Ceo's behind the vaccine now set to win the race for approval visors orla and biotechs or shaheen warlock sinks into his soft cream colored leather chair. It's good to finally meet in person. Yes it is strange to have worked so closely together on such an important project remotely the trials going. Well yes but we need to recruit more volunteers. Infection rates are dropping in a few places due to local measures which could put us off schedule. We're trying to identify where the next hot spots will be so we can recruit volunteers there. What about the election is that affecting things. It's a headache. Whatever we do with a vaccines right now. it gets treated like it's a move to supporter undermine one of the bitch. I hope saying not. Federal funding would insulate us from that. But no such luck he s it and there's not much we can do about that we're less sits upright or is there you know we're all trying to address this individually wonderful. The company's making vaccines got together and made a pledge. Pledge yes pledged to follow the science. No no to stand with science. I think everyone would sign up to that. Yes i i definitely would as soon as he returns to the. Us morla makes the calls on september eighth the stand with science pledge runs in newspapers across the nation it's signed by all of the american and european companies leading the push to create a vaccine including astrazeneca biontech johnson and johnson moderna and pfizer. They all vowed to uphold the scientific process and they all promise that none of them will ask the fda to approve their vaccines until they have evidence showing their safe and effective but within hours of the pledge going out across the nation. The news is overshadowed by a bigger story. Astrazeneca's trial has just been suspended on the next episode. Astra zeneca baffles the nation. The vaccines get caught in trump and biden's battled for votes and the first doses hit the road from wondering this is episode four vaccine wars for business wars. If you like our show please give us a five star rating in a review and be sure to tell. Your friends. subscribe on apple podcasts. Amazon music the wonder wondering app. or wherever. you're listening right. Now join three. Plus in the wonder he app to listen one week early and ask free. You'll also find some links and offers from our sponsors in the episode notes. Supporting them helps us. Keep offering our shows for free another way you can support. The show is by filling out a small survey at one dot com slash survey. And tell us which business stories you'd like to hear a quick note about re-creations you've been hearing in most cases. We can't know exactly what was said. Those scenes are dramatization but they are based on historical research. I'm your host david brown. Tristen donovan wrote this story. Karen low is our senior producer and editor edited and produced by. Emily frostburg voice acting by michelle. Phillipi sound design by kyle random. Kate young is our associate producer producer. Dave schilling our executive producers are jenny lower beckmann and marshal louis created by earn on lopez. Four one very look no further than wondering plus for the perfect mother's day gift. She'll get to enjoy our hit. Podcast even the rich ad free and so much more. Each season offers an in depth. Look at the lives and scandals of the rich and famous like the kardashians beyond saying jazy and brittany spears. Here's a quick preview. Twenty cops storm into the house. What the hell is going on. That's what lynn wants to know. One of the cops tells her we've got a fifty one fifty psychiatric hold. Were taking britney in this mother's day give wonder you plus by visiting wondering p l u. us dot com slash. Mom wondering feel the story.

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Moderna looks to speed up distribution as COVID variants worry experts

Quick News Daily Podcast

18:46 min | 5 months ago

Moderna looks to speed up distribution as COVID variants worry experts

"Progressive presents an interview with your upstairs neighbor. A it's rick from upstairs taken seriously when i play. R&b at one in the morning. That's me saying. Hey i'm here for you and i enjoy repetitive. Baselines expired batteries in my smoke detectors. Nice right. Yeah upstairs neighbors. Help people forget their troubles to focus on. Want to see how high joe aggressive can't save you from your upstairs neighbor. No let me try and get both weekend. Save you money when you bundle renter's auto insurance with us. Progressive casualty insurance company affiliates. Another insurer special discount not available in most situations. Today is tuesday february second and thanks for choosing quick news daily. Once again my name is brett. Spangler and on this show. We've got everything from a cool new policy from president biden to information about a new wave of immigration to the u k to moderna are trying to solve the vaccine distribution problems. They've been having plus whatever else we have time to get to. Let's get started right away. Shall we starting with that moderna news. They've asked the fda to authorize them to fill their co vaccine vials with fifteen doses of the vaccine currently there at ten doses per vial. The problem that they're running into is the fill finish process in the manufacturing cycle. The problem with this process is that it has to be done in a septic conditions. Meaning there is no contamination. A setup with that level of quality is really hard to come by so if they can do more like phil more in the vials which they would already be doing at places that they're already certified as aseptic. It'll help increase production basically. They're saying hey we have enough room in these vials. Why not this is a problem for us because we can't get all these manufacturing plants to be aseptic currently the total production. Vaccines is about one point. Two million doses per day but according to experts speed is of the essence and we really need to be around three million doses per day. Pfizer got approved for something similar and going from five to six. So this really shouldn't be an issue in the very near future. The uk could be seeing an influx of new immigrants from hong kong on sunday. The application for british national overseas visas opened. This new visa allows people to live work and study in the uk and eventually applied to become citizens. The only requirement is that applicants have to have enough money to support themselves for six months and prove that they don't have to urculo sus as i understand it. A version of this visa has been around since nineteen ninety seven which was in control of hong kong got handed over from the uk to china however the eligibility requirements got more loose. This past july so about seven thousand people have already arrived in the uk with it and three hundred thousand. More people from hong kong are expected to get there over the next five years. So why are people so eager to leave hong kong. If you'll remember. China passed a new security law this summer which changed the definitions of acts of subversion succession foreign collusion in terrorism to be broader as a result. Many people in hong kong. Think this isn't excuse for china to start arresting anyone who goes against them. Some people were even worried. That could be as simple as posting. Something negative about the government on whatever social media. They have a lot of people are also leaving to make sure that their children grow up more open society in. They're afraid the education system will start to change into pro china propaganda. This is really good for britain as well not. This should be the only reason to take an immigrants because anyone is capable of doing great things but sixty percent of people who have applied our families with young children and the other forty percent are either young couples or young professionals. So there's a really good chance that they're going to be some more really smart people who will be british citizens in just a few years. The cool new policy. That i mentioned from president biden is part of his by america. Executive order biden plans to replace the government's fleet of cars and trucks with electric vehicles. All assembled in the us. Now this will take some time because the only places that actually make electric vehicles in the us are tesla gm and nissan in florida recently announced that they have plans to do so in the near future. Frankly it sounds like a lot of details are still fuzzy. Is he gonna allow hybrids. What's this total cost gonna be in. What's the time frame on this thing. Because there are a lot of government vehicles the only thing that may have tipped us off just a bit is that he said the vehicles will produce net zero emissions not necessarily that they would have to be link one hundred percent electric just that they'd have to be net zero for carbon emissions. How ever biden did boast that it would create about one million new jobs in this area for the us auto industry so that would be something and it would certainly be an incentive for carmakers and for people to get on board with this thing just for context in two thousand nineteen. There were six hundred forty five thousand government vehicles that drove four point five billion miles into us three hundred and seventy five million gallons of gasoline and diesel thirty five percent of all those vehicles for the postal service. Speaking of which. I wonder what happened to our boy. Louis dejoy you remember him. I wonder if anything's gonna come to that if we have bigger fish to fry these days. So here's another segment. Where i have to go after some of the other people in the media for just an irresponsible story that happened so you might have seen the headline from the daily beast. Talking about oh. The white house is asking reporters what they're going to ask beforehand and they're trying to say reporters are so mad and they're scared they're like. Is this a free press. It's not really fair. If you can pick and choose what questions you answer but the problem. Is that some of the complaints that were filed with the white house. Press corps association or something like that. You don't know if that was just like fox. News max and owen but the worst part of all about running with this story is that they bury this paragraph twelve paragraphs in take a listen here quote. This practice isn't totally unheard of in previous administrations departments or federal agencies for instance former president. Donald trump's went house press secretary sarah huckabee. Sanders was known to vassar news outlets about their questions in advance of some major or high profile trump press conferences or events according to two people with direct knowledge of the matter communication. Staffers during the bush obama years would ask reporters for the gist of questions in advance. If they wanted to interview cabinet secretaries like how they bury that all the way at the bottom. And just say oh. Yeah by the way. People have done this before. Like that is super suspicious. This is like trying to create their obama tan suit scandal. Sadly i think we're gonna see more of this because by this sort of boring quote unquote to cover compared to trump like. There's not a scandal every other day so they have to come up with stuff like this instead and for the record. The white house hasn't denied this. They just said we do it. Because we don't wanna keep saying we'll get back to you on that we'll get back to you on that like god forbid there prepared so that they don't have to say that every other question come on people. I guess i'll take this opportunity to say that today mayor pete people judges can be confirmed as transportation secretary and alejandro may or kaz is also going to be confirmed today as the secretary of homeland security so again. I'm back to. I don't know what to say for these corona virus variants because it seems like sometimes there's good news sometimes. There's bad news it's really hard to interpret. I just don't wanna freak you guys out by sharing some of the worst news that i've been hearing or like reporting from doctors on twitter because you know i'm not a doctor myself so i can't really know if i'm interpreting all of these things correctly so the sources are on the page and you can check those out for yourselves in decide for yourself what you think. But i just don't want to be responsible for spreading too much misinformation or interpreting. Things wrong giving you a wrong idea about things ending on something a little bit more concrete. I wanna play of clips from both congresswoman katie porter from california and andrea Cortez the representative from new york as they've been talking last night and this morning about their whole ordeal on the sixth how they had to hide out from those insurrectionists. And you know it's tough. It's tough that people had to be in that position for as long as they were in. I think it's a good reminder for all of us because as happens as time passes maybe we forget what we're feeling in that moment or what that must have felt like for those people and this whole thing with impeachment has been politicized and we just forget about what happened. So let's hear talk about it on her. Instagram live last night in katie porter. Talked about it this morning here and the bathroom door starts going like this. Like the bath behind me rather in front of me. And i'm like this on the door hinges right here and just here where is she. Where is she and This was the moment where i thought everything was over Weird thing about moments like these is that you lose all sense of time In retrospect maybe it was four seconds. Maybe it was five seconds. Maybe it was ten seconds. Maybe was one second. I don't know if felt like my brain was able to have so many thoughts in that moment between these screams these yells of where is she wears she and so i go down and i just i mean i thought i was going to die It had a lot of thoughts. You have a lot of thoughts. I think when you're in a situation like that And like also one of those thoughts. That i had was in just happened to be a spiritual person be raised in that context in. I really just felt like you know if this is the plan for me Been people will be able to take it from here I had a lot of thoughts. But that was the thought that i had about you. All I felt that if this was the journey that my life was taking that. I felt that things were going to be okay. I was kind help you. What what are you looking for. And she said. I'm looking for where i'm going to hide and the thing will always stay with me. The two memories Your especially as a mom. I think we're just really powerful for me. Was when she said i said well. Don't worry i'm a mom. I'm called life everything here we need. We could live along in his office and she said i just hope i get to be a mom. I hope i don't die today. In the second thing is she was wearing heels. And i remember her saying to me. I was wondering flats at remember. Her saying to me ammunition wore heels. How am i going to run. And we went and we found her a pair of sneakers to wear from one of my staffers so that she could run if she needed to literally went for her life. How long did the fear of losing life in that room while you were waiting about six hours. There was no communication about what to do knowing he came to check on us. The capitol police never accounted for every member safety and so we heard voices in the hallway. We didn't know what they were whether those were police officers whether those were triggers so we just we stayed dark. We click the windows in the curtains. We turn their phones off. We silenced everything and we just sat as still it is quite as we could be in the hope that they would just run on by all right. I think that's going to do it for the news portion of the show here today. The only announcement i have on my end is i am going to be taking a brief break at least for tomorrow so no show on wednesday still just trying to settle into school and all of that so the plan is to back again on thursday otherwise you can still stay up to date by following me on instagram twitter facebook at quick news daily on any of those platforms nap and trying to do more re tweeting sharing for just news from other sources like nbc msnbc that sort of thing the ap so you can still get a good idea of what's going on from that otherwise stay safe out there. Stay home tied in there. If you're trying to fight off some kobe fatigue get vaccinated if you can and i'll see right back here on thursday. What do you wanna dot at all. I don't know what what what are we done. Bastard on yesterday. All the dolls say like the same. I like on monday. Who saw to die. There has beco- these days. Nothing is normal and everything is weird but you could still save big when you switch to progressive. That won't change not to or any dumb progressive dot com progressive casualty insurance company and affiliates. Me me me me me but also you the payroll fast forward. Favorite foreign film powder doughnut. Okay what's my line. The only line. I see here on the script. His options based on your budget with the name your price tool from progressive man. It's a tongue twister I'm sorry i'm going to need a few more minutes. Oh this wall. Risk the bogus. Well risk the name your price tool from progressive. The our nfl does coxswain risky. Insurance company and affiliates price and coverage match limited by state law.

president biden hong kong moderna news uk katie porter china biden white house moderna Louis dejoy Press corps association Spangler sarah huckabee us bush obama mayor pete
New COVID-19 Strain, Moderna Vaccine, CDC Vaccination Guidelines

NPR's Story of the Day

06:43 min | 6 months ago

New COVID-19 Strain, Moderna Vaccine, CDC Vaccination Guidelines

"There's some mixed news on the coronavirus this morning. There's a new strain of the virus in the uk it's spreading quickly and it is worrying. People including health professionals european countries are banning travelled to and from the uk some european countries. Now here in the in the us were on week. Two of our vaccination campaign shipments of the second vaccine that was authorized will be arriving across the country. That's the moderna vaccine. Npr's alison. Aubrey is with us. Good morning alison good morning. Can we start with what's going on in the uk and this new strain there what's happening scientists in the uk. Say this new strain accounts for more than sixty percent of recent cases identified in london and the concern. Noel is that it's more contagious. I spoke to angela. Rasmussen of allah gist at georgetown university. About this it does look to me that this may be more transmissible but it's important also for people to understand that that doesn't mean that it's being transmitted in a different way and it also doesn't seem to be associated with any increase in violence meaning. That people might be more likely to get it but they are not going to get more sick. She says there's still a lot more to learn about this mutation. Do we know if it's made it to the us well. It is possible that this strain could make it to the us restaurants and says it's really not known at this time. So she says it's one more reason to be vigilant. If it is more transmissible that means that it could result in work. Cova cases right now. Our healthcare system is string to its limits and an additional surgeon. Cases could really put us over the top and i mean big question. Here will the vaccine that people have been getting be effective against historian. Well admiral brought dharar atop administration officials said yesterday that they have not seen a single virus mutation yet that would evade the vaccine. Good news okay. So over the weekend. There's a cd. Advisory committee that issued guidance on which people are next in line to get the vaccine. Let's bring bring people up to date. Who's first who's getting it. I sure so. The next group will include people age. Seventy five and older Also frontline essential workers so this would include police. Firefighters teachers prison guards postal workers bus drivers and grocery store workers. And we've got both pfizer and moderna vaccine is going out this week. How many doses do you know. Are we talking about sure. A combined seven point nine million doses are ready to be distributed this week and this is very welcome news noel. Everyone knew that vaccine supplies would be very tight to begin but many sites have not received as many doses of the pfizer vaccine as they had been told to expect over the weekend. operation warp. Speed officials acknowledged fewer doses. Were released to start. These first. Few weeks i spoke to mike brownlee. He has vaccine distribution efforts at the university of iowa healthcare. He says they're on track to get about half of what they had been told to expect by year end. We were hoping to get by the end of the year. Ten thousand doses so that we can keep moving through our staff but we understand the challenges. So i think we're trying to be patient with the process at the moderna. Moderna provable help Aunts were just ready whenever we doses. We are ready every single day to give vaccine so a bit slower than expected but not a surprise that the first couple of weeks would be a little bumpy point out. Lawmakers on capitol hill have agreed to provide more than thirty billion dollars for vaccine purchases and vaccine distribution and cova testing. Is part of this new coronavirus relief package and from three thousand feed. How has this vaccination campaign which we keep describing as historic. How how's it been going. You know in the words of actor. Gabe kellen who is overseeing the rollout at johns hopkins in baltimore. He says it's going amazingly smoothly. He says they've seen no adverse events only very very mild side effects of any and an overwhelming response in terms of people wanting the vaccine. Now there's a certain miracle to this right like a vaccine in the midst of a world and them. It was developed in under ten months. We thought there'd be a lot of vaccine. Skeptics are people who would say well. I'm willing to go second. You go first but they want it now. The demand actually has way strip our best expectations and as to when it's available to all well president-elect biden's pick for surgeon general vivek murthy says it could be midsummer too early fall when the vaccine is available to all lower risk people in the general public. Okay that's interesting. So so the numbers change day to day but we have obviously seen a surge. This winter is the surge slowing down at all. You know not really no l. The us is averaging about two hundred and fifteen thousand new cases a day cases continue to increase in many parts of the country look at california arizona. Many southern states of georgia tennessee. Now there are places where new cases have begun to decline in the midwest. Iowa indiana michigan and kentucky to doctors and that state tell me the restrictions put in place by governor and eva sheer seemed to be helping him. What about death rates. Are they still going up. Death rates have increased about twenty percent in the last two weeks and while it is true. The oldest americans are at highest risk. There was a very touching photo of a couple died together last week. Noel reportedly held hands as they were dying from cove. It he was sixty two. She was sixty five and a new study from andrew. Levin a professor at dartmouth college finds that the risk of dying from covid for even middle aged people who get infected is much higher than the risk of dying in a car crash. Covert is dangerous much more dangerous than driving a car so we do things like wearing our seatbelts. Driving a safe speeds and we need to do more of that one hundred times more of that in terms of trying to make sure that we don't get infected with covid and that we don't onto someone else. And amid this holiday season the cdc continues to recommend the people postpone travel. Stay home. i know it can be disappointing to cancel your plans but as one psychologist put it noel. Disappointment does not kill but cova can. Npr's l. aubrey. Thank you thank you.

uk alison dharar atop administration pfizer mike brownlee university of iowa healthcare us Noel Aubrey georgetown university Cova Rasmussen Npr moderna Gabe kellen angela Advisory committee Moderna
Moderna Says It Can Make 600 Million Covid-19 Vaccine Doses This Year

WSJ Minute Briefing

01:40 min | 6 months ago

Moderna Says It Can Make 600 Million Covid-19 Vaccine Doses This Year

"Avalanche provides cloud based sales tax solutions for businesses of all sizes evola automatically integrates with more than seven hundred. Erp and ecommerce systems likely the systems used today learn more at avalon dot com slash wsj. Here's your midday brief for tuesday january. Fifth i'm jay waylon for the wall street journal drugmaker moderna says it'll be able to make at least six hundred million doses of its covid nineteen vaccine this year. That's one hundred million more than earlier projected. The company says it's supplied about eighteen million doses to the us government so far it expects about one hundred million doses will be available for use in the us by the end of march we reported exclusively that saudi arabia and russia have reached an agreement to maintain oil output levels through february and delay any increase until march news of the agreement pushed oil prices up by three point seven percent to fifty two dollars. Ninety eight cents a barrel. Since the start of the pandemic group of ten russia led oil producers have cut their daily output by about seven million barrels a day the group plans to restore a total of two million barrels. A day of output in the coming months and general motors says it's fourth quarter. Sales rose four point. Eight percent led by large increases for pickup trucks and big. Suv's the automaker reported strong sales of its top-selling vehicle the chevy silverado. Pickup as well as the chevy suburban and tahoe. Suv's for the year gm sales fell twelve percent. We'll have a lot more coverage of the day's news on the wsj's what's news. Podcast you can add to your playlist on your smart speaker or listen and subscribe wherever you get your podcasts.

jay waylon moderna Avalanche wsj russia us government saudi arabia gm us silverado chevy tahoe
A Third COVID Vaccine is Poised to Enter the U.S. Market

Business Wars Daily

04:45 min | 4 months ago

A Third COVID Vaccine is Poised to Enter the U.S. Market

"Business wars daily is supported by microsoft teams. Microsoft teams is helping priority. Bicycles transformed the way. They work after closing their new york city showroom. They started doing virtual visits on teams. Now people from all over the world can come into their showroom learn more at microsoft dot com slash teams from wondering. I'm david brown. And this is business. Wars daily on this tuesday february night twenty. Three million americans have already rolled up their sleeves to receive at least the initial dose of either the pfizer vaccine or the moderna vaccine designed to prevent covid nineteen. Well now a third vaccine is on track to enter the us market. Johnson and johnson's corona virus vaccine just wrapped up a long-awaited trial and hopes to clear. Fda authorization by the middle of this month. The lure of johnson and johnson's vaccine is that unlike modera advisor it can be delivered in one shot that make distribution simpler with no need to follow up with a second dose. It's also relatively inexpensive compared to the others and while moderna advisors vaccines have to be stored at just the right temperature. Well below freezing. Johnson and johnson's doesn't have those stringent requirements for storage. It can stay viable in just a refrigerator for around three months. That means the vaccine will play a big role globally because it's easier to distribute to low and middle income countries. According to the new york times but the results of johnson and johnson's trial were a bit disappointing. At least at first glance trial results indicated that it was seventy two percent effective at preventing moderate to severe symptoms of covid in the us. That number is sufficiently lower than modern and pfizer's overall efficiency rates of around ninety four percent and johnson and johnson's rate drops to sixty six percent in latin american countries and to fifty seven percent in south africa which is dealing with a variant strain of the virus. But don't let those lower numbers food you scientists and immunologists say that johnson and johnson's vaccine is still extremely effective and researchers have warned that you shouldn't compare the effectiveness of the three vaccines because they were all developed and tested at different periods of kovic evolution. Dr william shafter an infectious disease expert at vanderbilt told the new york times that pfizer and moderna had an advantage because those companies did their clinical trials before the variant strains emerged. He said quote. Johnson and johnson was testing. Its vaccine not only against the standard strain but they had the variants now in a perfect world. Consumers might get a choice of which of these vaccines they'd like to receive but that would only be possible if there were enough doses of all three and right now. That's just not the case in early january. The new york times reported that the us only had one hundred eighty five million doses of pfizer and moderna vaccines to cover americans through june and at the same time doses that were produced quickly now risk expiring before they can get into the arms of those who need them. Johnson and johnson says that if they're vaccine is approved they can produce around one hundred million doses of their vaccine by june which would certainly increase access. But there's one thing that all vaccine makers need to look out for those variant strains of the disease which are already present in around thirty two countries including some parts of the us the various of already been shown to lessen the effectiveness of some vaccines including and johnson's so the next step in this fight according to experts yet as many people as possible as quickly as possible to roll up their sleeves and get the shot from wondering. This is business wars daily. I'm your host david. Brown written and produced by jessica your muskie edited by emma courtland. Our executive producers are jenny lowered boecklin and marshall louis created by or non lopez four one. Microsoft teams is helping priority bicycles reinvent. The way they work when the pandemic hit the bike shop had to close their new york city showroom. They found a way to reopen by doing virtual visits on teams. Now the team can meet with two or three times the number of customers than they could before and people from all over the world can visit their showroom learn more about their story and others at microsoft dot com slash teams.

johnson pfizer microsoft Johnson moderna advisors The new york times david brown Dr william shafter new york city us Fda moderna infectious disease vanderbilt south africa emma courtland
Global Markets Rise After Dow Closes at Record

WSJ Minute Briefing

01:24 min | 3 months ago

Global Markets Rise After Dow Closes at Record

"Here's your morning brief for thursday march eleventh. I'm kief collins for the wall street journal. Markets in asia ended higher european shares. Were mostly early. Trading day after the dow jones industrials closed at a record. High above thirty. Two thousand investors will be watching. Us weekly jobless numbers due out this morning. Moderna says it has begun human testing of a modified covid nineteen vaccine designed to better target a highly infectious strain. I identified in south africa. The company's original covid nineteen vaccine which is among those being used in the. Us was highly effective in a large clinical study but lab testing it has shown signs of reduced potency against the south african variant. President biden is expected to discuss the nation's corona virus response tonight as he delivers his first primetime address. The biden administration is also planning promotional campaign to explain. What's inside the one point nine trillion dollar relief package that the president is set to sign into law. On friday and a senate subcommittee today is scheduled to hold. Its first hearing on possible measures to strengthen the country's antitrust law congress considering the most significant changes to the law in decades as both parties have been galvanized but concerns about powerful tech companies. We've a lot more coverage of the day's news in the wsj's what's news. Podcast you can add it to your playlist on your smart speaker or listen and subscribe wherever you get your podcasts.

kief collins President biden Moderna wsj biden administration asia Us south africa senate congress
U.S. Stocks Edge Down After Yesterday's Rebound

WSJ Minute Briefing

02:10 min | Last month

U.S. Stocks Edge Down After Yesterday's Rebound

"Nobody builds five g horizon bills. Five g we made fast even faster with verizon. Five g ultra wide band already in parts of many major cities. This is pushing us. It's verizon versus verizon this is five jeep built right. Here's the closing bell. Brief for tuesday may twenty fifth. I'm charlie turner for the wall street journal. Us stocks dipped lower giving up modest early gains. The dow jones industrial snapped a three day winning streak for eighty one points to close at thirty four thousand three twelve. The nasdaq composite lost four points. The s&p five hundred dropped eight. The loss is followed. Monday's gains which were prompted by comments from the federal reserve indicating that officials were not concerned that rising inflation could stamp out growth new data out today gave a mixed picture of the us economy home price. Growth climbed in march to the highest level in fifteen years as housing demand continued to outpace supply and after a gain in april consumer confidence for may remained mostly unchanged signaling that americans optimism for the economy has plateaued in corporate news. Shares of moderna rose three point one percent after the drug maker said its covid. Nineteen vaccine was effective in children between the ages of twelve and seventeen the electric truck maker lordstown motors plunged nearly seven and a half percent after the company said it was facing higher than expected costs and cut. It's twenty twenty one production forecast and as the vaccine rollout continues in the country. Reopens americans are booking their travel plans. Shares of cruise liners. Rose with royal caribbean gaining. Nearly three point. Seven percent and norwegian cruise lines rising nearly three point six percent. We'll have more coverage of the day's news on the wall street. Journal's what's news podcast you can add to your playlist on your smart speaker or listen and subscribe wherever you get your podcasts. Nobody builds five g like verizon bills five g. we made fast even faster with verizon. Five g ultra wide band already in parts of many major cities. This is us pushing us. It's verizon versus verizon this is five jeep built right.

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Moderna Says Its COVID-19 Vaccine Is Safe and Works For Teens

TIME's Top Stories

01:54 min | Last month

Moderna Says Its COVID-19 Vaccine Is Safe and Works For Teens

"Moderna says its covid. Nineteen vaccine is safe and works for teens by alice. Park in a release on may twenty fifth. Madonna says its vaccine is safe and efficacious among twelve to eighteen year olds. The company reported results from its combined phase two and three study involving more than thirty seven hundred teens who were randomly assigned to receive either two doses of its covid nineteen vaccine or two doses off placebo. The study was designed to compare results among the teens to those among adults which led to the company's current emergency use authorization for its vaccine. Researchers are looking to see if the results among teens are at least as good and not worse than those among adults. And that's what the company reported. There were no cases of covid. Nineteen reported fourteen days after the teenage study. Participants received two doses of the shot compared to four cases among those receiving a placebo meaning. The vaccine was one hundred percent efficacious and protecting against disease. The company said that the vaccine was also ninety three percent efficacious in protecting against even one symptom of covid nineteen disease after one dose. Maternal is the second company to reportcovid vaccine results among teens in march visor bio in tech reported similar safety and efficacy of one hundred percent and its study and received authorization from the fda for its to dose shot among teens in may both medina and finds her bio intech vaccines or built on. 'em are in a technology which involves using genetic material from the covid nineteen virus to train the immune system to fight it dern plans to submit the latest data from the teens to the us food and drug administration to expand the current authorisation for its vaccine to children as young as twelve years old.

Moderna Madonna alice us food and drug administratio medina dern
Novavax Reports Its COVID-19 Vaccine is 96% Efficacious, Based on Phase 3 Trial Results

TIME's Top Stories

05:42 min | 3 months ago

Novavax Reports Its COVID-19 Vaccine is 96% Efficacious, Based on Phase 3 Trial Results

"Nevada's reports its covid. Nineteen vaccine is ninety. Six percent efficacious bastogne phase three trial results by alice. Park novak's reported on march eleventh. That its covid. Nineteen vaccine is ninety. Six percent efficacious in reducing mild moderate or severe disease. The maryland based company joins the handful of manufacturers that have reported encouraging data on a covid nineteen vaccine three pfizer bio tech moderna and johnson and johnson's janssen pharmaceuticals have already received emergency use authorization for their shots from the us. Food and drug administration. Novak's revealed the final results of its phase. Three human trials of envy x covy. Two three seven three in a press release. The findings have not been submitted for peer review scientific journal yet. The company reported that overall it's vaccine was ninety six percent efficacious in protecting people from mild moderate or severe covid nineteen disease if they were infected with the original sars cuvee to virus. The vaccine was slightly less efficacious at eighty six percent and protecting against disease if people were infected with the b one one seven strain of the virus which is becoming dominant in the uk where the study was conducted that gives the vaccine and overall efficacy of eighty nine point seven percent against both the original and uk variance by comparison visor bio and tech's vaccine is ninety five percent efficacious against cove nineteen disease. Maderna's is ninety four percent and johnson and johnson's is sixty six percent in an ongoing phase. Two b study of the vaccine in south africa where a more worrisome variant is increasingly responsible. For a growing share of new infections novak's. His shot is so far fifty five percent efficacious and protecting against covid nineteen symptoms. I did not think it was possible to have a vaccine. Prevent ninety six percent of any respiratory disease says the gregory glenn president of research and development that novak's that's outstanding and. I'm personally ecstatic. If you had asked me a year ago to predict the very best vaccine we could expect. I would have said eighty or eighty five percent efficacy against any respiratory disease would be pretty amazing. Glenn joined the company just over a decade ago. Because he was intrigued by its vaccine strategy and the case of covid nineteen that entails inserting the gene for a sars covy to protein into an insect virus and then infecting cells from an armyworm the larval stage of a type of moth that infects cabbages with this modified virus. Those cells then act like a living copying machine pumping out copies of the sars cuvee two protein that protein is then suspended in a molecular bubble and injected into the body where human immune cells recognize it as foreign and mount defenses against it. It's a beautiful system for making the sars covy to protein says glen it has to be made with absolute fidelity especially for a viral respiratory disease. Or it doesn't work and today. We are announcing validation of that system. The strategy is designed to mimic as closely as possible. The way viruses would activate the immune system during natural infection. That's a potential advantage since such a response is in theory the one that is broadest and most complete and likely that provides the most protection. The company has used the technology in a flu vaccine but some of the steps including extracting the sars covy to protein from the armyworm cells developed specifically for the covid nineteen vaccine novak says phase three trial included more than fifteen thousand people in the uk ranging in age from eighteen to eighty four years. Old half of whom were randomly assigned to get the vaccine which is given in two doses and half of whom received placebos only five cases of severe covid nineteen were reported in the study all among those getting the placebo while encouraged by the results. Glenn says his team like those at the other vaccine manufacturers are studying whether a booster dose might be needed to sustain the level of protection. The study found vaccine. Immunity doesn't last forever. He says i think the immune response is going to fall off after six to twelve months. And we're going to need to boost. Nova vaccine is also studying a so called by vaillant vaccine targeted against both the original sars. Cov two and the more worrisome south african variant boosting would this vaccine glenn says would provide the broadest protection glenn wouldn't specify how much of the stockpile of doses the company has already manufactured but says novak is in discussions with both uk and us regulators about next steps to prepare for possible authorization. The company hopes to file for emergency use authorization in the us during the next quarter in the meanwhile start to increase production with manufacturing partners in india spain uk korea and japan nova vaccines vaccine can be stored at refrigerated temperatures which could make attractive for more vaccination sites that don't have the freezer capabilities that the bio tech and modern vaccines require. The company has committed to providing one point one billion doses of its vaccine to the global kovacs enterprise run jointly by the world health organization gabby and the coalition for epidemic preparedness innovations.

Park novak severe disease johnson's janssen pharmaceutic peer review scientific journal johnson Maderna respiratory disease gregory glenn moderna uk Novak
U.S. Stocks Finish Mixed as Tech Shares Drop

WSJ Minute Briefing

01:39 min | 4 months ago

U.S. Stocks Finish Mixed as Tech Shares Drop

"News laws and regulations are changing by the day. We get it and at adp. We're here to help guide you with up to the minute compliance expertise so you can pay your people accurately and on-time regardless of what each new day may bring learn more at adp dot com. Here's the closing bell brief for wednesday february seventeenth. I'm charlie turner for the wall street journal. Us stocks ended the day. Mixed as the dow industrials eke out another record. The dow rose ninety points to close at thirty one thousand six thirteen. The nasdaq composite lost. Eighty two points. The s&p five hundred fell one point. Markets ended mostly lower despite signs that the. Us economy is improving. The commerce department said this morning. The january retail sales rose five point. Three percent as consumers spent down their stimulus checks after driving. Most of the recent rally shares pulled back today. Apple lost one point. Eight percent while netflix fell just over one percent and executives and directors of several drug companies developing covid vaccines profited handsomely last year from sales of their company stocks officials from thirteen companies including moderna adviser sold more than eight point five million shares last year for a total of nearly five hundred million dollars. According to insider transaction data from kaleidoscope some of the sales toward the end of last year have raised calls from government officials for restrictions on the trading plans under which these sales were made. We'll have more coverage of the day's news on the wall street. Journal's what's news podcast you can add it to your playlist on your smart speaker or listen and subscribe wherever you get your podcasts.

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Moderna to Seek Health Regulators' Approval for Covid-19 Vaccine

WSJ Minute Briefing

01:29 min | 7 months ago

Moderna to Seek Health Regulators' Approval for Covid-19 Vaccine

"This episode is sponsored by. Sap your business and sap solutions together. We got this. Here's your mid daybreak. From monday. November thirtieth i'm jr whalen for the street journal. Truckmaker moderna says it will ask. Us in european health regulators today to authorize its kobe. Nineteen vaccine it. S food and drug administration clears the shot distribution. Could start within weeks. It could be the second to go into use in the us. By year's end a vaccine from pfizer in biontech is already under review a government watchdog says the labor department has consistently reported inaccurate estimates of the number of individuals receiving jobless benefits throughout the pandemic. The government accountability office says that's resulted in lower than appropriate payments to some workers and we report exclusively that facebook is nearing a deal to buy customer a startup that specializes in customer service platforms and chat bots people familiar with the matter. Say the deal could be completed as soon as this afternoon. It would value new york based customer at a little over one billion dollars. We'll have a lot more coverage of the day's news on the wsj's what's news. Podcast you can add to your playlist on your smart speaker or listen and subscribe wherever you get your podcasts. Twenty twenty didn't see. That one coming disrupted supply chains employees working from home customers changing their minds at sap. We've helped hundreds of thousands of companies face their business challenges together. We got this. Learn more at sap dot com slash together.

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