17 Burst results for "Mechanism Of Action"
"mechanism action" Discussed on Mark Bell's Power Project
"The day like high green prior like when he was sixteen years old who green fifteen or six Jesus out, green. Okay. Anyway, you look at these athletes that have great genetics. Right. And if for example, let's say all substances became leave, or a certain amount of substances became legal for certain sports. Those athletes are still going to be a head of every other fricken athlete. It's just gonna like every ethic gets a little bit better. But the ones once the top are gonna stay at the top. So I mean, it's it gets difficult to wonder like okay if we let everybody on what's really going to make terms of a difference. Okay. People aren't getting bad. But the guys at the top in the woman at the top aren't they still just going to be the people at the top? Yeah. I mean when we had branch worn on that was kind of like the question at Asamoah. Okay. Well, what happens if? We pull all of the know anabolics out, he's like the same top five people will still be the top five people, and it's like shit. I guess you're right. And then records just won't be. Yeah. Just won't be as big a records won't be as high the times won't be as fast. But the same genetic God-given genetic with same discipline intensity workouts. The same five six will be there. So a number of athletes will actually. Will ask questions about performance enhancement drugs because it's an insurance policy now they've on top of the game best in the world, and that's worth us upon. They'll have a question. Well, what about I know where he coming going with us? What about if I got a little bit. I know little bit. I said, well, you asked the question, so here's has to do not with the -bility as whack seeing waning there. Little more mature now. The younger troops are coming in or twenties. This person may be later twenties. Thirties now still wants to be a top of the game. But thinking I can't keep up recover like those twenty year olds ten years ago. And like I was, so it's an insurance policy when they start asking questions, do you think it would help me? What if I said, well, lemme splaine you the mechanisms actions the pros and cons, just like we're discussing here. So. It's not because they're looking at to be bigger stronger faster. They're already big strong fast. They wanna maintain psychologically, because there ten twelve years older now. Yeah. Some of these athletes are put up on such a pedestal. And we love admire them so much, we're, we're thinking, like now, like they wouldn't do he wouldn't do it that way, you know, a lot of times that's what people are thinking. And if you look at someone like Michael Jordan, it's like that's probably like the most highly competitive person. Maybe walked the face of the earth, and it's like did he beat the Detroit Pistons, just because he decided to start working out harder or, you know, you know, or was because he so highly competitive, he's like, I'm tired of getting the shit beat out of me by the pistons, I'm gonna train, and maybe he trained and maybe he stumbled upon some stuff. I'm not saying he did. Or didn't I have no idea, but it definitely could be possible. I mean he somebody like him did get bigger as as career progressed. I think the you know Barry Bonds is in the same position where Barry Bonds already headed to halt name regardless. And then he got bigger and stronger later in his career. He wasn't even really a home run hitter. He that he hit a lot of home runs beforehand. But. He really started smacking the crap on wall later on. And I actually think it's a b twelve injections. Got him swallow made his neck really big at all. See as taking made his head really large. Yeah. But you're right. Market is super fascinating. And like I was just reading article I think it was a college player from Clemson football player. He got caught with Austrian. So he he was spending the whole year. It's like some right? Yeah..
"mechanism action" Discussed on The Flow Artists Podcast
"But once I got that sorted out felt I felt they could safe. And if it turns out that cancer cells truly are more sensitive to the effects of heat than normal cells. And if it's true that chanting these chance has therapeutic benefit, and if it's true that chanting in water potential the chance if any of those are true, then I might get some benefit and it's not doing any harm and I kinda like it. And so I did it. And so that was my philosophy. You know, it's, it's like I'm not gonna wait for the data at all come in, because maybe what if they have a study that, you know, that comes out in ten years? Hours that says that chanting helps you know, lower or improve cancer, healing rates, probably not going to do the study, but soon they did. And they found was was I supposed to, like, wait until the data's in, you know, we have this idea and no one's funding that study known responding no money. Because no one's going to financially benefit from it, and who's gonna pay for a study of fasting who benefits when, when you fast only you because you're inning less food. You're not consume. Any any you're it's like no one's paying for a study in maybe some government someplace, but pretty much the stuff isn't getting studied. It might be benefit. I mean, certainly I have no doubt the fasting help me. I mean my doctors were amazed that I sailed through the first day at my chemotherapy. I mean they'd given me these lectures on an -ticipant, Tori, nausea and vomiting. That's when the vomiting is so bad with the first round of chemotherapy, that people start vomiting hours before the next infusion of chemotherapy and anticipation becomes us like conditioned response in its debilitating. I'd had two or three separate lectures on this by by Makala gist. And the nurse manager was signed to my case and I didn't have any knows vomiting at all. And I also think it probably made the treatments more effective. Am I convinced at the hot tub and the hyperthermia and the chanting hadn't a benefit? No would I rule it out. Also know. And the thing is what's never studied in western medical. Studies is the potential synergy between things because reduction is science needs to isolate one variable and study just what happens. Many change in one variable. That's the way modern science works, and it's brilliant. It's a brilliant methodology, but it's limited in that it doesn't notice interconnections synergies. And what if chanting by itself, wouldn't be shown to be valuable in a study? But what if chanting on top of meditation on top of us in our practice on top of chemotherapy on top of fasting? What if in that instance it does as some incremental benefit? Will that study is never going to be done? No matter who just because we don't. Study things that way, we don't study multiple things, and how they work in, in fact doctors don't like that kind of study. Because then you can't isolate, which are the parts that are effective and which ones are not. But if in fact, something isn't effective in isolation but is affect of in combination, those affects are systematically, never examined, or found leave your background your pretty quickly place to be out of research, different treatments and really analyze them? What advice do you have for the rest of us? So pay darn have that background because looking online, they're a Sawyer many really predatory people who just want to sell shonky remedies to people are in a desperate phase of the alive, and this also. Well, meaning people have advice that is not going to be helpful for everyone. I did have the advantage, not only of being a physician not only of how. Spent twenty five years studying holistic healing, but of also been connected in those worlds being able to pick up the phone or Email a friend who's won the stories at tell them book is I have a friend who's trained in Chinese medicine. And when I started to get a lot of side effects from the radiation and chemotherapy, we ended up setting up a video conference, and we spent like an hour hour and a half on the phone and just and she went through options. She ended up, recommending some Chinese herbs in, in Chinese medical Sav, but which I ended up using a while and when I was trying to avoid fibrosis of the neck, which is a potentially debilitating after a fact of the treatments, which nobody mentioned to me. I I only uncovered it in my research she recommended. I start using Castrol packs. But the point is. Yeah, for for someone who doesn't have this training. I think it can be overwhelming. And I think if you can you need to get help and I think whether it's an integrative physician or. Or somebody else, who's ideally, I think someone who can put a foot in both worlds now my particular bias. And I talk about this, a great deal in the book and I'll just go to briefly here. I think we've got a misconception about healthcare. We've been taught to divide the world into conventional you know, medical modern medicine scientific medicine, whatever you wanna call it in one hand and alternative and complementary medicine on the other hand, I think it's false distinction. Not philosophically defensible. It's arbitrary, which category. Many things get put it. The real difference in healthcare is between holistic remedies in approaches, and reductionist, once so drugs, and surgery and other things or reductions measures these can be extremely effective, but reductions measures tend to have more side effects, they tend to cost more money and often they're someone profiting from their use. And so there's a lot of marketing in so some times that marketing is sup. Terrain Ian union, even know than information. You're getting you're reading in the magazine, or the, on the internet about the drug is influenced by the drug company, but it is well, unfortunately, because of this false distinction into alternate conventional a lot of stuff in alternative medicine is what I call alternative reductionism. It's basically high doses of specific chemicals often in pill form, sometimes even infused, intravenously that are used trying to create a specific biochemical effect in the body. That's a reductionist mechanism action K, a holistic mechanism of action is it goes back to that quotation you read the beginning, which is the idea of treating the soil to benefit the plant? And so we're doing things to strengthen the person to detach defy the person to give them better nutrition to boost their immune function all. All these things that are not disease specific. They're not based on the western medical diagnosis, and these various symptoms like yoga therapy, and all your data and tuck Chinese medicine have diagnostic methods where they detect imbalances of various kinds, three people could have the same diagnosis, but haven't for different, energetic reasons as seen by these traditional systems, and their approach would not be to treat the diagnosis, but the treat energetic, imbalance, and this is one reason, by the way, why almost all studies of holistic healing are going to underestimate their benefits because advocates of evidence based medicine, which is the dominant ideology and healthcare, these days insist that you study things by disease. And so they don't allow the doctor. They don't allow the Chinese medical healer. They don't allow the yoga therapist to. To detect the imbalance, and then tailor the treatment to the imbalance, they're supposed to say. Well, this person has low back pain, which yoga poses should we use, and part of what I teach in my yoga therapy worships, this is this is not how yoga therapy works. The I mean you know, it's like a third rate imitation of your therapy, what it is, is a holistic system turned into reductionist disease based tool, which is not what it's meant to be. And so the problem is when you're treating using these Listrik systems using these reductionist protocols based on western medical diagnosis. Some people are getting the wrong treatment as seen by the traditional system, because they're being traded for probably the more common energetic imbalance, but it's not the one that they've got and someone's the wrong treatment. And so, but that's the way that that right now conventional medicine. When they even study holistic healing methods insist they'd be studied in part of the reason I wrote saving my neck is I want to blow up this idea because it's bankrupt and I'm basically using science and not some kind of woo analysis. I'm showing why it's scientifically flawed to study holistic healing in this way and how it leads to mistakes and because of this false clumping of everything alternative into one category. You have all these beautiful ancient healing systems, and all these dietary supplements, and all these megadose vitamins, which sometimes can be helpful, but the reductions treatments, they have more side effects, they become less effective over time. They often have subterranean marketing, and if you don't understand it if you think, oh, vitamins, earn the same categories as yoga, I like yoga. I'm gonna take vitamins. You know, in fact, there are studies and I talk about one of the book, heavy cigarette smokers who take vitamin d supplements have been shown to develop lung cancer at higher rates than people who don't take them. These are not benign, even though they've been put in the category that makes people think they're benign. So I think you're generally safe going with acupuncture, Chinese medicine for someone who knows what they're doing off the shelf patent medicines that are made in China and other places where you're maybe not quite so sure of the quality, and you can you be careful, you know, but if you know where to get your herbs, and you have sources you trust, and you have people who are advising you what you need based on their ability to read, your energetic imbalances of your pulse diagnosis and tongue diagnosis and interviews and the other methods. They use I think that stuff is safe. I think body workers, generally safe yoga, not just going to a random yoga class, but yoga. Therapy, which is someone who's trained to look at what imbalance you have. And, you know, when I teach yoga therapy, I divide the holistic terrain into structure nervous system and breath, I interviewed psychology and spirituality. And so I look for imbalances in any of those categories, and then based on the imbalances. I target yoga tools lifestyle interventions dietary interventions based on your radar mostly to try to tackle the imbalances. We see to bring the person into better balance with the idea that they'll do better with any condition will tend to get better. When when as you said, you like enr Ganic Gardner, you make the soil, stronger, and I remember you mentioning in the book that you'll have attic, wtma in India, initially didn't want trae e because he said, there was no evidence that you've added will help can Slough. We all know that there's one hundred different schools in yoga, what many of us, don't realize one hundred schools of all your beta to, and there's different. Gurus different systems and the stu- the system in Carola is different than the north Indian stuff. That's in almost all the books that make it to the west. And so generally, my IRA doctor who, who died, a couple years ago didn't take any patients who didn't have something he knew he could help them with. And so many static cancer is something that he's not convinced he can he can help now because I've been a student for many years, they made an exception for me. But generally, no, they don't treat it. But one of the things I said to so Krishna is my is my body, who was was my doctor trying to divide the main system for many years. And I told him Krishna I'm not looking iradar to Kermit cancer. I just wanna bounce me and strengthened me and get me ready for what's coming. And then after I had all the toxic chemicals and, and the. Radiation therapy, then went back and specially spent three months just doing the super long slow treatment just to try to bring me back into balance and, and really save him. My next starts in the month before I begin treatment wanna go to India for treatment, and ends pretty much in the in the three months that I'm recovering for treatment. And then you know, kind of going back to all the stuff in between. Yeah, that's a really interesting kata the book actually that was my favorite pot, because I feel like this third was the acute phase. That was your treatment. That was how you navigated that then the rest of the book was the rest of your life, that led up to that point when you've got this diagnosis when you're riding it did all of that stuff. Just pour out. Or was it a conscious exercise to be lack? Right. I am going to sit down and untenable this takes me so I went India with the files, I would need if I decided to work on the book because I had the book before I. Book idea, and I started to work on a little bit in the summer. And so this was the November when I went so summer northern hemisphere being June-July started work on the book. And then by November when I went there, I felt like if I ended up on the book, I would work on it, but I had no expectation than I would. But just I was open to that. Possibility was prepared for it. If it happened, I brought some files and things that I would need if I was going to work on now normally when I'm home writing, which between workshops, I remember primarily a writer, I consider a thousand words, a good day. Bye write a thousand words in a day, I'm pretty happy. And what happened to me about four or five days, after I got to India, it just started pouring out of me and I wrote in a little more than three months, two hundred fifty thousand words..
"mechanism action" Discussed on News Radio 1190 KEX
"What are some of the main benefits that people might expect to see once they go from being vitamin d deficient? And as you say to becoming vitamin d sufficient, how should they be feeling or what should they see differently? Well, the first thing that you'll notice this feeling in your well being and you're just think clear, but as time goes on if you'll notice differences in your gums and teeth, and if you ask anybody who's taking this product has taken it for several months, just ask them about their fingernail. What's the change? What's the difference in your fingernail? Now. These are things you can experience. See, no. What does it do to your fingernails grow quicker or they become harder? They become less riddle shinier. It's really a remarkable change in your fingernail. But it takes more than a month because it takes about six months for the fingernails grow. But these are things we can see and feel vitamin d affects thirty six Oregon. So feel what it's doing in your pancreas. What is doing for your blood pressure or your prostate? But we don't have time to talk about these thirty six organs, but what we're talking about is the immune system. The pancreas. The heart blood pressure muscle string, brain activity prostate health, rest health, Colin hill, bone marrow teeth and gums kidney lung retina skin stomach uterus. I mean that could go on. But again because activated vitamin d is a steroid hormone. It can affect all these organs because there's two thousand genes that it is the key to those jeans, and it depends upon which organ it is in which gene is involved. So there's two thousand mechanisms action that's very important to understand because you know, we've been jaded with vitamin claims vitamin c and vitamin either going to feel better you're going to do this. You're going to it cetera. And so people find it hard to believe. I mean, if vitamin d only did one thing they'd find it easier. To believe, but they just have to remember the mechanism of action, which is unique to any vitamin you mentioned colon health here, my family physician as a precautionary move. Put me on a pretty healthy dose of vitamin d. What's the connection what the reason you're gastroenterologist? Did that is because there's just a wealth of studies now that are coming out showing that colon health and vitamin D. Level are connected. But they're the same. Studies about breast health the same studies about prostate health insurance policy. You're not not to take this. And it's free. And the other thing I I wanna say as you listen in five years. I don't want you to say, I didn't know about this. I was never told. I mean five years from now, I don't want you to turn around and say, I didn't know about. Because you've been polled right now. You're being told you know, you can't say you never you never knew about it. Because I'm telling you right now, it's involved, for example in a number of places in the country. If you walk into emergency room with anything that might be your heart. You know, what they do one hundred thousand units right off the bat. First thing a hundred thousand years of vitamin d and then they keep giving. Speaking of the cardiovascular system, and I know you could probably talk for about thirty minutes on this. But some of the the information you sent me here. Just fascinating. What Bytom indeed does talk about its role in maintaining a healthy cardiovascular system. Yeah. Same clues. We know that heart health is better the closer you live to Quaker. We know heart health is better in the summer than the winter. But just recently there have been a slew of studies out of the best universities in the world all connecting your vitamin D level to your heart health. There's a study, for example, at a Harvard by a friend of mine, professor Edward yovany Chee and his conclusion was pretty start here. It is quote, low levels of vitamin d R societas with higher risks in a graded man, even after controlling for known risk factors that is even after they control for smoking high blood pressure, high triglycerides, diabetes, all the things known to contribute, even after they control for that. There was wrong. Effect of vitamin d and it was integrated manner that is if you're really deficient than your risk is much higher. If you're a little deficient than your risk is a little higher, and we don't have enough studies yet to say that you know, if you have heart disease, you should take vitamin d although many cardiologists prescribing it just on the basis of why not it is safe. You know five thousand units today. It cannot make anybody toxic five thousand years today is ten minutes of some are even five minutes summer, sunshine. So the way these doctors are thinking is look what's the risk versus what's the benefit? It looks like from the studies. There's a tremendous risk associated with vitamin d deficiency. We don't have all the studies we need and we're doing those studies now, but it would be unethical to let people remain vitamin d deficient. While we're conducting all the studies we need to about heart health or bone health or breast held or prostate health or immune system. It would be unethical to let them wait vitamin d deficient. The problem is that many doctors use antiquated reference ranges, and so if you're levels thirty five they'll tell you. That's okay. It's not okay. Level needs to be fifty or higher and get that adults need five thousand units today again for those just tune in. I mentioned earlier, you know, I go through the health food store look at multivitamins, most of them at best have four hundred I use when you're looking at the the vitamin d that you can buy by itself as a standalone vitamin most or four hundred I use I saw a couple that were thousand I you tablets, but again that falls far short of that five thousand number, and that's what you get with purity here, why is that so important. There's recently been studied by professor Haney at Creighton university that shows that when you get your level to fifty your body has enough for all the things that needs to do. And it begins to store a little bit of the vitamin d just like your ancestors used to store. So if your level is less than fifty your body is basically using up all the. The vitamin d as fast as you take it for all the things that needs it to think of vitamin d is a mountain spring with a pool at the top, right? The pool we've always known about is calcium in bone and we've taken enough item in data halfway fill up that calcium in bone pool. But all the other pools below the breast pull the colon pool. The immune system pool all the other polls that are blow. It have been basically dry since we've been out of the sun. If you take five thousand units of vitamin d the upper pool overflows and starts filling in all the pools at the bottom teeth and gum the mood, the cognition the pancreas. So all these pools, and there's enough leftover to store a little bit for a rainy day a little bit of a surplus. Yeah. But you don't do that unless you're levels around fifty if you're levels less than around fifty you use up almost all of it immediately, and that's called chronic substrate.
"mechanism action" Discussed on 77WABC Radio
"What are some of the main benefits the people might expect to see once they go from being vitamin d deficient? Is you say to becoming vitamin d sufficient how should they be feeling or what should they see differently? Well, the first thing you'll notice this feeling in your wellbeing. And you're just think clear, but as time goes on if you'll notice differences in your gums and teeth, and if you ask anybody who's taking this product and has taken it for several months, just ask them about their fingernail, ask them. What's the change? What's the difference in your fingernail? Now. These are things you can experience. Now does it. What does it do to your fingernails grow quicker or they become? Harder. They become less riddle shinier. It's really a remarkable change in your finger enough. But it takes more than a month because it takes about six months for the fingernails to grow. But these are things we can see and feel vitamin d affects thirty six Oregon. So feel what it's doing in your pancreas. What it's doing for your blood pressure. You know, or your prostate, but we don't have time to talk about these thirty Oregon's, but what we're talking about is the immune system. The pancreas the heart blood pressure muscle strength, brain activity, prostate health, breast health, colon health, bone marrow teeth and gums kidney lung retina skin stomach uterus. I mean, I could go on again. Because activated vitamin d is a steroid hormone. It can affect all these organs because there's two thousand genes that it is the key to those jeans, and it depends upon which Oregon it is in which gene is involved. So there's two thousand mechanisms action that's very important to understand because you know, we've been jaded with Bytom in claims vitamin c and vitamin either gonna feel better you're going to do this. You're gonna it cetera. And so people find it hard to believe. I mean if item indeed only did one thing they find it easier. To believe, but they just have to remember the mechanism of action, which is unique to any vitamin you mentioned colon health here, my family physician as precautionary move put me on a pretty healthy dose of vitamin d. What's the connection what the reason you're gastroenterologist? Did that is because there's just a wealth of studies now that are coming out showing that colon health and vitamin D. Level are connected. But Pat, they're the same. Studies about breast hell the same. Studies about prostate health. This is like an insurance policy. You're not to take this. And it's free. And the other thing I I wanna say you're listening in five years. I don't want you to say, I didn't know about this. I was never told. I mean five years from now, I don't want you to turn around and say, I didn't know about I wish I would've known because you've been polled at right now, you're being told, you know, you can't say you never you never knew about it. Because I'm telling you right now, it's involved, for example in a number of places in the country. If you walk into emergency room with anything that might be your heart. You know, what they do one hundred thousand units right off the bat. First thing hundred thousand units of vitamin d and then they keep giving. Speaking of the cardiovascular system, and I know you could probably talk for about thirty minutes on this. But some of the the information you sent me here. Just fascinating what vitamin d does talk about its role in maintaining a healthy cardiovascular system. Yeah. Same clues. We know that heart health is better the closer you live to the equator, we know heart health is better in the summer than the winter. But just recently there have been a slew of studies out of the best universities in the world all connecting your vitamin D level to your heart health. There's a study for example, out of Harvard by a friend of mine, professor Edward yovany Chia and his conclusion was pretty start here. It is quote, low levels of vitamin d or associated with higher risks in a graded man, even after controlling for known risk factors that is even after they control for smoking high blood pressure, high triglycerides, diabetes, all the things known to contribute, even after they control for that. There was a strong. Wrong effect of vitamin d and it was integrated manner that is if you're really deficient than your risk is much higher. If you're a little deficient than your risk is a little higher, and we don't have enough studies yet to say that you know, if you have heart disease, you should take vitamin d although many cardiologists prescribing it just on the basis of why not it is safe. You know five thousand units today. It cannot make anybody toxic five thousand years today is ten minutes of summer, Sean, even five minutes of summer, sunshine. So the way these doctors you're thinking is look what's the risk versus what's the benefit? It looks like from the studies. There's a tremendous risk associated with vitamin d deficiency. We don't have all the studies we need and we're doing those studies now, but it would be unethical to let people remain vitamin d deficient. While we're conducting all the studies we need to about heart health, bone health, or breast or prostate, health or immune system. It would be unethical to let them wait fight him. Indeed efficient. The problem is that many doctors use antiquated reference ranges, and so if you're levels thirty five they'll tell you. That's okay. It's not okay. Level needs to be fifty or higher and to get that adults need five thousand units today again for those just tuning in. I mentioned earlier, you know, I go through the health food store look at multivitamins most of them at best have four hundred I use. But when you're looking at the the vitamin d that you can buy by itself as a standalone vitamin most or four hundred I use I saw a couple that were thousand I you tablets, but again that falls far short of that five thousand number, and that's what you get with purity here, why is that so important. There's recently been studied by professor Haney at Creighton university that shows that when you get your level to fifty your body has enough for all the things that needs to do. And it begins to store a little bit of the vitamin d just like your ancestors used to store. So if your level is less than fifty your body is basically using up all. All the vitamin d as fast as you take it for all the things that need to think of vitamin d as a mountain spring with a pool at the top, right? The pool we've always known about is calcium in bone and we've taken enough item in data halfway fill up that calcium in bone pool. But all the other pools below at the breath pool. The colon pull the immune system. Pull all the other polls that are blowing have been basically dry since we've been out of the night. If you take five thousand units of vitamin d the upper pool overflows and starts filling in all the pools at the bottom teeth and gums, the mood, the cognition. The pancreas all these pools. And there's enough leftover to store a little bit for a rainy day a little bit of a surplus. Yeah. But you don't do that unless you're levels around fifty if you're levels less than around fifty you use up almost all of it immediately. And that's called chronic substrate starvation. Wow. And that's. It's not a.
"mechanism action" Discussed on WIBC 93.1FM
"We start off by doing younger and added more manageable diet, it was two shots a day and then one before bedtime, and then as I got a little bit older it moved to every time. I wanted to eat something at a shot that can get myself does insulin shots are what managed blood sugar in type. One patients longtime that easy use. Cowan pork problem. You be injecting like a foreign substance or like people get reactions or get bad. Just skin reactions even their entire body can have bad allergic reactions to it. So I think it's still available in Europe. I've never seen anybody here in the United States on this. But nowadays, it's all recombinant DNA facing to design. Human or human insulin that what you're actually injecting. And there's a lot of different formulations. There are different when you look at the molecular structure of insulin there. A and b are now. A and B or alpha beta chain, and you can manipulate those beings alab Domincan either act fast or very slow or like a basil. Flat into unto remarkable white. What what they can do to act quicker. So in in kind of dairy, the mechanism action and the other way to manage blood sugar is with diet thousand diabetic, I know I would be eating junk would be doing nothing LB. I've definitely always made. Sure to make sure have like a pretty steady diet as far as making sure not over eating the junk food and eating like meeting enough healthy food to make sure my blood sugar stays in check. Just because I mean, whenever your blood sugar is out of whack. I mean, you just feel awful every day you wake up, but I mean, you have those days where most people think they're hung over. They wake up after night a drink. And they don't do anything that day you wake up and your blood sugars three four hundred it feels like there's glue running through your veins..
"mechanism action" Discussed on Ben Greenfield Fitness
"Use it for morale and commonly with anything and it's not going to disturb your natural growth hormone production. Now that said a caveat. That's obviously as long as you're not like abusing hip umbrella. Like I've seen broS and bodybuilder guys talking about using it like four times a day. Like a boom does or what they call a saturation does. Which again, I don't even know what that means anymore. But I've read people that done that. I'm sure if you do that then yes, you're going to disturb natural production of growth hormone. But if you just use it around at like three. Hundred micrograms before bed, and then maybe if you want to extend it do in the morning to same dosage, you definitely will have better sleep, better skin quality. I think a little bit of improve fat loss again, you know, depending on your diet. And if you have everything else dialed it and stuff like that. But that's it. You know, it's not you're not gonna have muscle gain. I mean, again, you know, people talk about growth hormone, releasing analogs peptides HGH to have does have synergy with anabolic hormones, and I'm sure that's true. I mean, look it obviously professional bodybuilders, but those guys are using super physiological levels of everything. And you have no idea, it's poly pharmacy. Who knows what's going on? Right. So in what I'm at? And where you, and I are at we're in like, obviously extending life, you know, using therapeutic things and doing things that make us feel better. I don't think that any of the peptides do that much with the exception being Tessema Rowan. And if you want to jump into that if you have any questions before into that because I I am fascinated by Tessa Marrone. So for for people who were going to use Merlin to enhance growth hormone to has a profound impact on sleep as well. Like, like, a morning, dose and evening dose. One thing that we should we should clarify. And I'm curious if the same could be. Said for this Tessema role in that you're about to talk about is that you typically want to combine it with a growth hormone releasing. Yeah. Like like CG twelve ninety five is one very common one because they have different mechanisms action, they work on different receptors. And you know, what one is growth hormone, releasing hormone and receptor and the other one is the girl in receptor which helps stable at your your appetite that these to work on. But you can you can literally get a five to six times affect of something like a growth hormone secreted Gog like Morella, if you combine it with something like a CG c twelve ninety five for example..
"mechanism action" Discussed on Point of Inquiry
"Learn. How to recruit those muscles themselves so working with pelvic floor, physical therapist. It'd be very helpful. I kinda like notch working with a trainer, right? Like, you're learning. How to do your exercises correctly having somebody who's an expert in it can be very helpful. And so public for physical therapist is also someone to see. And then also there's other causes of incontinence that can't be fixed with pelvic floor exercises. So senior Khanakala gist. Also can be useful in trying to decide. What of incontinence? You have. I want to switch the subject a little bit the SIMS blog covered this recently. There seems to be a big discrepancy between the the efficacy and safety of D's. And what people believe about UD's. Yes. Where does that come from? And. And should people be less worried about a UD's in general? Well, you know, everybody has a different respect if it ratio that they can tolerate. So I think that's really important to think about like there's people who will never get on airplanes terrified, and there's people who fly almost every day. So, you know, we have different respectful ratios. So these are probably the safest most effective form of contraception. When we say safe, you have to take everything into consideration. It's not just the actual safety device. But how effective it is preventive from getting pregnant right being his maternal mortality risk pregnancy in. So I think that with a lot of scientific information, especially as it relates to women's health there other forces involved, so we're talking about either this stream writer or not even the extreme. Right. Who are who have ideas that ides's abortifacents, which they are not the mechanism action has nothing to do with preventing implantation of effort lies. Egg. The other aspect is. We have sort of this extreme left who wants women to do only natural things because I'm not sure why because I guess dying in childbirth is his better. I I don't know the two big pharma. Yeah. I yeah. That's exactly how you're sticking it to big pharma by by, you know, having no control of your reproductive life. So so we have these forces that perhaps are more vocal now than they were. And it's easy to fear people, right fears of big motivator, which is again, why the skeptic community is really here because we recognize that people are motivated by forces that are not, you know, not necessarily brilliant, presenting accurate information. So I would say that you know, you can find excellent evidence evidence based medicine about evidence based information about injury during devices from the American Congress OBGYN from the World Health Organization from Planned Parenthood. Those are really good valid sources the national library medicine, uneven currently, health and human serve. Mrs that last time I checked you never know but inherently they have accurate information. So these are highly effective very high degree of user satisfaction in. So when you look at two years into sort of using a method of birth control if you chosen UD, you're more likely to be using your method of birth control two years than if you've chosen anything else. So so they're very effective. They're very safe. But obviously nothing is free. I mean walking across the isn't risk free. And. Yeah. And there there are very true. Stories about people's experiences with UD's, but you know, I certainly wouldn't wanna have. But, but it is good to know that there's there's good information out there, and we can kind of Riva little when making these decisions instead of being so afraid, and I know I know what that's like because fear brought me to skeptics movement. But I could talk about that her hours. Thanks so much for being here, gen my pleasure. Thanks so much for having me. Can't right to my next guests I interviewed for at sei con as well, Abby. Hey for author scientist, educator and public speaker her book the nut so intelligent designer. Why of Lucien explains the human body end? Intelligent design does not debunks intelligent design her scientific career includes a doctorate in zoology from Oxford, University, teaching human anatomy and physiology at curry college. She has recently brought Interscope to include crushing the gender binary using biology..
"mechanism action" Discussed on The Keto Answers Podcast
"To depenetration deeper, and so near infrared light is little bit better for for deeper tissue treatment, must recovering joint pain and things like that. So houses differ from let's say an infrared sauna where people have I think use a combination of far mid and near infrared, correct? Because I don't think I know of any size, for example that have red light in them yet. So what's the difference with that? Yes. So both both great. Both great therapy sauna or heat base there versus a photo by oscillation different. Dick, very different. It's kind of like the now's used I like to use his is Tim. About like most people are familiar with like, wait based training and cardiovascular training, right? Typically, you don't go run go for a jog or run while your while you're lifting do bicycles. Right. You don't really do different. Right. They're both good ideal. You want a little bit of both. But but they're different the different forms of therapy. So so saunas are great the goal of sauna is to induce heat stress. And so that's why far infrared mid and far infrared wavelengths are often used in saunas because you want to actually heat up your body. You're trying to heat stress on your body. So that that's the mechanism action is just different. Whereas light therapy. You're actually delivering very specific wavelengths of light that have that that that can induce certain action within the mighty contra of ourselves to produce more energy. So like light therapy like the basis or the kind of the high level concept is is you're you're helping yourselves proves more energy, whereas saunas, you're actually inducing heat. Stress and then allowing your body to respond to that similar like, you know, it's very similar cardiovascular exercise, quite honestly when you look at the clinical data, so both great just very different. And so when some of the us have the near infrared. Light. Whereas you said you're also has that for example. I mean, you might get a little bit of those benefits..
"mechanism action" Discussed on Bulletproof Radio
"Your experience? I love coffee date on coffees. Awesome. Because all the polyphenyls air. Yeah. So I love coffee. I understand some people can't tolerate because that's just normal with everything, but I this study talking about they're talking specifically about caffeine. You just got caffeine tablets. Yeah, it was caffeine. Tablets they use is going to give you an adrenaline. Becton adrenaline is a potent epinephrine eight potent that mobilizer so it would just increase keep him production up in Efren. They didn't say the mechanism they just showed we sure that's okay. Got it. And I definitely know that that combination. Which which, you know there's all sorts of reasons that I think synergistic reasons that it works. It works, but in my own life tournament brain on having been a former RAV Egan and autumn Yeshivas in Venables and just recovered from way more than most humans deal with. And then to be at the peak of my health in my mid forties I know is because I manage my conduct crazy. I've regularly have have key tones in my system. I take my condo stimulators. We manufacture some as supplements things, unusual delivery systems for p. q. and keep those cynic acid and precursors and derives all these different things. I rotate them around and all, but the difference in in the clear to my thinking and my ability to fly across the country in Nabi zombie it, it feels super human to me. And yeah, I do everything because it's just how I am because I don't want to go back to where I was. How much. Might Okondo's simulation does the average person need to feel a difference, whether it's owner something else, you know how you feel it can be misleading so you can have somebody that feels really tired run down because their dreams are no good. This is classic an extra -ality. There might conjure just fine. So the but they feel like crap. So I, I went up talking patients that I said, well, think of those guys that are in the toward frosts. They obviously have pretty good minor convert, but the end of the day they're pretty pooped out. So that's kind of how goes eat. So you have great. Might still be heavier dreams, wasted the art of it. If you're drained, really good, and you might come to shot, you might actually say yourself, you know, I feel pretty good. Now what you won't know is you know, how do you feel when you ride your bike of a mountain pass. Because people that say, I feel really good and at the same time at format contra Panchen, basically people sit on the bud all day long and they never really tested out. They have, no, they don't know what their maximum might of. There's such a low level of existence. They don't really notice the difference. Okay. Athletes, notice of a regular. Don't necessarily notice that there might upon going bad every year. The first place it shows up in my research is a cognitive function little tweaks on cognitive function because you have so much metal controversy in the brain, and I can't quite remember that or the more the emotional crankiness. And for those people, you give them a medal contra stimulant, whether it's ozone or Indies. Other compounds, their emotional regularity improves to the point that the stuff we is in Kito prime in two different studies is now approved for for claims on improves the emotional symptoms of PMS. So can get that additional crankiness that comes in. You take something that I'm hypothesizing here, meth, the mechanism actions that it's increasing contra function because it does that. And then all of a sudden people have better emotional control. Have you, do you see that in patients report improvements in mood when when you work on them out of contra interestingly enough would when you're talking? I'm thinking about a psychiatrist in New York that reported to our society couple years ago. Then he finds that ozone therapy is pretty good for you. All kinds of these mental disturbances that he sees. So I thought that's pretty darn interesting. What's the mechanism behind all that? It's probably half infectious and imagine how the brain that brands figures a lot of stuff out. You wanted to be working pretty well you, you do indeed..
"mechanism action" Discussed on The Peter Attia Drive
"I got this pre lots of Email internet, we got a fax from journalists saying he was writing an article on our paper and another paper from Stryer and actually sent us stewards paper which we thought was really unethical at the time. And so we, we actually at that point contact Stewart and said, hey, we got your paper, you should know we're working on this Tuban and here's our paper so is yeah, I didn't know at all. And in many ways I was very naive, right? I was in this lob, Saul bass led us do whatever we wanted to. We had this drug on bone Sasol. I started working on this thing and Stewart had had a history of gay, follow six mechanism action. So it was a logical progression to what he was doing. Salt was not. It was funny. He came from a world where people looked for the receptors drugs. So if you look at his history, he really looked for receptors for drugs for small molecules including the endorphins, for example. But he wasn't big on cloning what we call cloning gene, which is where you have that get the DNA sequence. You almost thought you didn't need to do that once five that you could study the protein. So I was one of the first people there to actually clone a CDN as as we call it in his lab so that it was a fun time because it was clear that we've done this protein. The pure did this time because your paper which was in cell was nine hundred ninety four, four. Yeah. I worked like crazy really like crazy. So, and that lab in general work like crazy. We were. It was very common to be there until one in the morning, and I would usually show up seven eight in the morning. We would sleep in the lab a lot. And once once things started to go. So we were purify purified out of the rat at a rap rain. So we killed hundred rats to do this in my friend, help me kill them. Take the brains out. There's a method in biology to visualize proteins called Silverstein, which is a very sensitive way. Of seeing a protein and the first silver taint stain, I did where actually sauce or a glimpse of them Tor on on this method. I remember that really clearly because at that point I knew I do it. How did you know it was toward the tour, looking at all the controls, and there was this band on what we call a gel. They showed up just in the right place. And so I was like, okay, there is a protein here that has all the properties that I want. And at that time, what properties did you know? You didn't know it size? Did you didn't know what size? But we know abound to f k b p rapamycin, but you didn't know that that exclusively bound to did you. We didn't, but we knew that it could be competed by six, basically competition type experiments. So we had done that. So there was these features. It was mostly the specificity that it required rapamycin to bind Gabi Gabe. And that was crystal clear in the earliest Burma when we had f- Gabia by itself, there was no band on the gel, and when we add up mice and there it was added FDA fall. Six clearly went away. And so we knew that that thing had all the right properties, but I remember very strongly feeling okay, not the time. Now we have very, very sensitive methods to sequence proteins lords of mass trauma to there we didn't. And so from what I saw Joe to actually figure out what it sequent ones, I knew it was hard, but I knew it could happen. I was very powerful feelings existence principle. Exactly. So I knew the thing kind of the enemy existed, and I get it, but then going from that initial glimpse on gel to then having enough to actually sequence at, that's what took pundits of rats to actually get to enough that I could buy it. And eventually we Claver this guy called Paul temps at a Memorial Sloan Kettering New York, and he was able to sequence enough of the protein that then through a whole variety of molecular biology tricks, we will to clone it, and it was a really huge CNA which basically is the length of the DNA sequencing codes it. It was very big, sort of in eighteen..
"mechanism action" Discussed on Bulletproof Radio
"It's really fascinating that you say that there's a certain class of people I call them science trolls and and their basic mechanisms action is that didn't happen because it can't and the it can't comes from via known mechanisms of action. But if you'll get almost every medical intervention that is shown to work clinically over the past hundred years, the story that scientists have told themselves about why it works is almost always proven wrong twenty years later. It doesn't change the fact that it worked. So we have this sort of scientific arrogance that says, well, we know everything works. And I think we might know about how maybe two percent of people of things in people's bodies actually work. And the rest of it were still pushing that. But it doesn't mean we should withhold useful therapies from ourselves because we don't have a clear story about how it works. I just like, sorry, leprechaun's maybe works because of leprechauns. But does it work is the first and foremost thing, and then we can decide if his leprechauns or not, but but that's secondary order academic importance. If you can just say, is their efficacy and is their safety, and if so, let's start helping people, especially people were suffering greatly because otherwise waiting until they're dead, so we can be sure we're safe. Doesn't seem very safe to me. I think that's, I think that's really a. What of the one of the shortfalls of institutionalized medicine? I mean, it's the fact that medicine got organized had a lot of benefit. I mean, you don't have the traveling, snakes, Saco sales, you know, and and who knows what, what you're getting, what it's going to do. But on the other hand, it can get so organized around guidelines and things like that that there's no longer any ability to really innovate and and there's so much fear about stepping outside the bounds of Elton. It -ly it comes down to. Just to beating a dead horse here, but about the risks and benefits for a given individual patient. You know their quality of life, talk to me about the typical dose of ketamine producing these antidepressant facts. The typical dose we dosing by weight and. You know, the typical anaesthetic doses probably four to eight milligrams per kilogram the dose that we use starts anywhere from a quarter of a milligram kiss point, two, five milligrams per kilogram up to, you know, to sometimes two and a half, three milligrams per kilogram. Usually we're giving at that high doses were actually usually giving it a couple of two injections to extend the trip. So this is really interesting. And you know, this is where ketamine and and I think the other psychedelics diverged from the classic paradigm of medicine where it doesn't matter how you feel about the medicine or whether you're wear that you're getting the medicine or whether you're in a coma or you take it before you go to sleep..
"mechanism action" Discussed on Bloomberg Radio New York
"Devices aircraft parts these log at twenty five percent tariff on things like electronic touch screens medical devices including pacemakers and artificial joints so we've got a couple responses one from the courier journal in louisville kentucky the senate majority leader mitch mcconnell says that he's quote nervous about what appears to be a growing trend in the trump administration to levy tariffs and then on the chinese side sheen wise come out saying that it will take same scale reciprocal measures says that china strongly opposes the us list it says that the report or this report doesn't give any details of what actual reciprocal measures china might be planning china's planning to resort wto dispute mechanism actions and we'll do so soon but china says it's confident it has the capability to deal with any protectionist measures from the united states and that is check to the media nine minutes now before the top of the paul to you all right thanks very much brian well last sunday saw a first of its kind class training spiring female lawmakers in japan joined on the phone from tokyo now by bloomberg's is about reynolds to discuss what the school hopes to achieve isabel thanks for joining us some limits may be stopped by describing the situation because the lack of gender diversity in japanese politics is rather striking by any standard isn't it he is i mean compared to any other developed country japan is doing terribly terribly badly any have ten percent women and the more powerful lower house of parliament and the situation is even worse and prime minister shinzo base ruling liberal democratic hoc that we've got something more like that think six percent women so this really to be done so isabella it stuck in new york and i'm curious about this is basically challenging obey and and his entire way of thinking as well as the mid perhaps it more broadly the rest of patriarchal society in japan but but who is is leading this i guess we can call it an effort to reform things well her name is she's a veteran member of parliament she's really been a child blazer and that she's been a member of the liberal democratic party's since a very young age and to be a lawmaker and a woman in the liberal democratic party was was extremely unusual in those days it was it.
"mechanism action" Discussed on C-SPAN Radio
"N one eight seven nine to see these high levels of resistance emerging to that class of drugs so it was remarkable that this company took the lead in developing a new class of antiviral drug that has attributes of a single does and so the five days of twice a day dosing it brings down the viral load in the patient very rapidly faster than they currently approved and a viral drugs and it has this new mechanism action so if a virus becomes resistant to the only approved class of drugs we have now this drug woods still work and eric bright is the director of barreda also views potentially in combination with the existing class of drugs another thing exciting about this drug is that they partnered now with a usbased company that usbased company has taken a lead in bringing that to the fda for discussions and consideration for approval in the united states and their plans to transfer the knowledge and capability to manufacture that dry in the united states in the near term so again it's one of about a dozen or a half dozen promising candidates with new mechanisms of actions several those supported by barreda and even monoclonal antibodies to make better treatments for blue oh i can't help myself on this was the chairman for the for the benefit of the german hop is that up rick bright said that this is very extraordinary that the company did this however the first recognition of this particular mechanism was in a paper from 1979 in the proceedings of the national academy of sciences from authored by the national institutes of health okay it's entitled transfer of white prime terminal cap of globulin m rna to influenza viral complimentary rna during transcription so we're just goes to show you i mean that basic science is the root of everything we do even something that twenty years later turns into a product made by a japanese company thank you dr anthony fauci than age what will will lecture that's good you know and that's part of why we did 21st century cures to continue that funding of that cycle and all i was well committee chair greg walton next question about domestic manufacturing vaccines and threats and opportunities but my time has expired and maybe we can get some of that uh the.
"mechanism action" Discussed on KQED Radio
"For years if they've worked in the been great and people have responded to them but no one's thought about what happens after the histamine response and many of these patients and uh a testing a drug effort in a new paradigm in a new phase of the allergic response requires some new methods and new ways of thinking about what's meaningful in clinical trials in what isn't meaningful in clinical trials so here to four we've tried to fit ourselves in the antihistamine box and terms of clinical design in terms of clinical and points no more so we're moving loves era the gloves are off for you were doing something different in new and meaningful to a huge population and so we're gonna try and change the paradigm a little bit which you know a new mechanism action sometimes deserves a new way of clinical testing so how is it different well the rich so each is a great way of assessing the clinical effect of a drug in allergic conjuncture vitus it's what we call a surrogate for disease rate how well someone um how much when each is how well itching is reduced after after drug administration is a good surrogate for how well their disease as being treated their more things than it should in allergic conjuncture vitus it turns out to be a very good way of assessing the effect of a drug and the severity of a disease patients rate hitch on a scale from zero to four four being severe zero being i have no edge and everything else in between and so there was a model develops many years ago it's been used for almost all allergic injunctive itis drug approvals to date where you give patients a drug you wait a little bit and you put allergen in there i literally early elliot and stick it right in the air and of course they have this big machine hi youth inflammatory response i can't imagine andrea first why did i agree that they have right the next thing listen right i'm not getting paid enough rate is probably what they say initially um uh the antihistamines to a.
"mechanism action" Discussed on Bulletproof Radio
"The mechanism action there is what you just described it it's that you think that isn't it's essentially helping molecules hold together battle better while they're doing what they do i think in this case the carbon structured is holding that single molecule together that's allowing this communication do what we think we have found here and this is gonna take the rest of my career to prove out because it's a complete change in our understanding of how human biology happens but that's keeps happening other microscope every day in our laps so this nieto now dates back almost seven years ago when we started putting this under microscopes eye i was already consuming a 'cause i you know and it's very exciting initial results right in my clinic uh in myself we had some objective measures them and basically some biohacking tools um similar to what you guys are using and was seeing almost instantaneous changes and so i was taking the compound we're starting to cell biology experiments i was started in two re reunite with some of my colleagues at the university of virginia to access some of the capacity for their thought processes around what this thing to potentially do but the goosebumps moments that were really unfolding at this point was that all of my all my cancer research and before that all my research and neurobiology i was really into neuro chemistry and the effects of the hormone system on how it doesn real plasticized eu before my cancer research and so whether we're talking about the brain or we're talking about my diabetes managment clinic or the cancer all of that understanding that i had gotten throw my research in intense study and blah blah was all discovered were learned if you will in a sterile petri dish we have never studied a human cell when it's in touch with the potential of a communication network that extra human and that that's what this molecule family suddenly offered is what if the bacteria in fungaya talking and what if they can talk to us and perhaps your poorly than that where they are talking to our might at qendra yes and that was.
"mechanism action" Discussed on Bulletproof Radio
"Okay as well go with there is so at i'm always orcas i people say oh frequencies yeah of course i and and it's like okay well frequencies can be measured and like okay was the frequency of your ceiling fan that's very different than what the frequency of your radio station and like a light has gotten the frequency of the latest cells in and there's a blink rate so amazon what does frequency really mean because it just means how often per second but how can white per second exact way in what you're talking about there and your sounds have frequencies and you can measure light or senate hurts because it's just how often per second but some call the pierre's electric effects absolutely happens and we know that light and heat can trigger appears electricity right where you can get a small electrical signals from sound ends so there are materials that respond that way said to these are desks up that use infrared and then we don't especially could also be light an attack leave us infrared okay and it was ever that would power them probably and that actually there's good science behind alec infrared light from your matter country changes water into exclusions on water so there is a basically a bits the core of of really inge jim you're doing organic biochemistry there's this is happening the there there's a conceivable angle there and i am always i've had like fifty different peoples of tried this patch and always kind of like if it's the nicotine patch if there is a frequent mechanism action there but other times i've funded only we've like their cells in your body that do stuff you have no knowledge of inviolate the stuff in your got him no knowledge that but it turns things unlawfully ores.
"mechanism action" Discussed on The Science Show
"Yes i do i'm mental the number of people with schizophrenia that have come out publicly and doing things and telling people that have schizophrenia the range of images of people with schizophrenia is constantly surprising may i mean like when india lead is it seemed like every person would schizophrenia was an artist you not because it was easy to market innocence now you know you get people with schizophrenia in other professions on to unfortunately suck general let's here gear much has changed in the last ten or fifteen years much still needs to be done professor david couple of feels that scientific breakthroughs will occur think it's like many fields of science if you look at a yearbyyear basis you sometimes feel disappointed disillusioned but if you look over ten or fifteen year timespan you realize what tremendous changes have occurred and i think we will learn a lot more about the function of the brain in relation to schizophrenia we will learn a lot more about different sorts of drugs not just me to or mimicking drugs but we will learn about drugs with an entirely different mechanism action that are effective in schizophrenia and i think the imaging techniques for example the look at the function of the brain will continue to reveal important things about schizophrenia the hats to we will have less fear of the human mind and less fear of people who are different marinner epstein whose father and sister both had a mental illness and her sister committed suicide.