35 Burst results for "Lou Gehrig"
"lou gehrig" Discussed on How to Live A Fantastic Life
"Right. Really was not the right way to let people live. No, I agree. Really hastened true demise quickly because of the things that they did to protect her from the virus. That's such a good point. I mean, overdoses are up tremendously suicides are up tremendously because of all the measures we did to protect us from COVID put a whole bunch of other populations at risk. Overdoses have almost doubled over the time frame of COVID. It's just astounding. Yes, and I think that's really important that people realize that now many of these overdoses are really suicides in which people are trying to get out of their grief. I have some knowledge of some people in my. Neighborhood that have died that way. And it's sad because really that this shouldn't be happening. In fact, in some locales, the number of people dying from overdoses now outweigh those that are dying from COVID. Yeah. Overdoses whether it's intentional or accidental. You know, and I lost a family member to both. You know, my mom died by overdose. She committed suicide with pills, you know? And then my son died of an accidental overdose. And for me, it all comes back to grief and trauma because unresolved grief and trauma leads to so many of these other things. It leads to addiction. It leads to depression. It leads to isolation. It just is this perpetuating thing. And especially suicide, once you have a suicide happen in your family, the chances for another suicide goes up, exponentially. And so really meeting families at the moment of crisis and making sure that they get help and they find healing and support is just paramount. If we don't reach all these families that are grieving because of COVID and a couple of years, we're just going to have even more addiction and even more suicide if people don't get the help that they need right now. Yeah, I think that's true. You know, I went through a phase in my life when I was diagnosed as having ALS Lou Gehrig's disease, and I was told I had 6 months to live. Wow. My affairs in order. Fortunately, that was not the proper diagnosis. But that was such a sustained trauma that I went through the phases of grieving. I went through anger, I went through denial. I went through bargaining. I went through depression, all those phases that were not very nice. And I think of all those phases, the worst phase, I think, was the depression phase where everything was black and you have no meaning to go on living. I think that depression phase is what drives people over the deep end into that phase where suicide or uglier ugly things happen, such as a drug overdose. Yeah, yeah, absolutely. That dark, heavy, sorrow, and just staying stuck in that place of trauma is a thing that we help people to do.
Roberta Flack has ALS, now 'impossible to sing,' rep says
"Musician Roberta Flack has revealed she is unable to sing because of a medical condition I'm Archie's are a letter with the latest Roberta Flack has been diagnosed with ALS also known as Lou Gehrig's disease Flax management says it makes it impossible for her to sing and not easy to speak Flank who's 85 is best known for songs like killing me softly with his song the closer I get to you and feel like making love the announcement comes just as a documentary about flack called Roberta will premiere Thursday at the DOC NYC film
"lou gehrig" Discussed on WABE 90.1 FM
"This is all things considered from NPR news. I want a summers. And I melt the Chang. The Food and Drug Administration has approved a controversial new drug for the fatal condition known as ALS or Lou Gehrig's disease. And pierce John Hamilton reports that the decision is being hailed by patients and advocates, but questioned by some scientists. The FDA approved the drug named religio based on a study of just 137 patients. But cullin 8 Bellas, president of the ALS association, says the decision is very good news for people with the disease. Right now, they're just aren't a lot of drugs available. And they offer only a modest benefit, as a result, people with ALS typically die within two to 5 years of a diagnosis. But says religio may give them an extra 5 to 6 months or more. 6 months can be someone attending their daughter's graduation a wedding, the birth of a child. These are really big monumental things that many people want to make sure that they're around to see and be a part of. But there's an ongoing debate about the drug's effectiveness. Experts who advise the FDA voted against approval in March, then they reverse their position during a rare second meeting a few weeks ago. Doctor David rind of the institute for clinical and economic review says it's hard to interpret the results of a single small drug trial. I totally understand why people would be trying to figure out a way to get this to patients. There's just a general concern out there that maybe the trial is wrong. A much larger trial of the drug is underway, rinne says a negative result would be a major blow. If you've got a drug that's extending life by 5 months, you ought to be able to show that in a larger trial. In the meantime, rinse is perhaps the company should charge less than the announced price of a $158,000 a year. Religio is the only product made by amylose pharmaceuticals. The Massachusetts company was founded by Josh Cohen and Justin clee, who attended Brown university together. Cleese says the drug is priced to allow the company to develop even better treatments. This is not a cure. We need to keep investing until we cure ALS. Cle also promised that amyx will reevaluate its drug based on the results of a larger trial called Phoenix. If the Phoenix trial is not successful, we will do what's right for patients, which includes taking the drug voluntarily off the market. Cohen and cleve though acknowledge that the decision isn't theirs alone. It would require support from the company's investors and its board of directors. John Hamilton NPR news. Orchestras across the country are gearing up for their fall seasons, but as audiences look at the stages, they will find very few black musicians on them. An organization called the black orchestral network is hoping to change that situation. Jeff London reports last spring, I went to a concert of the national symphony orchestra in Washington, D.C.. There was only one black musician on stage, a couple of days later, I spoke with Jennifer Arnold, one of the founders of the black orchestral network. There's a real neat to actually be transparent about what's happening in the industry in terms of black people. Arnold played viola with the organ symphony for 15 seasons and now as director of artistic planning and operations for the Richmond symphony. She says the last study on racial diversity in American orchestras came out in 2014. We do not know how many black people are in orchestras. And I say that as a representative black orchestral networks, one of our calls is let's start collecting data. Let's find out have we done better than the 1.4% number that is going out there. Many black musicians in orchestras
FDA skeptical of benefits from experimental ALS drug
"The food and drug administration has issued a negative review of a closely watched experimental drug for the illness known as Lou Gehrig's disease the FDA review comes ahead of a meeting this week for outside experts to vote on the drug for ALS the medication has been the focal point of a lobbying campaign by patients their families and lawmakers FDA reviewers have said that the single study from analytics pharmaceuticals was quote not persuasive due to missing data errors in enrolling patients and other problems they also said that regulators were not convinced by data that the company said show the drug helped patients live six months longer I'm surely ocular
"lou gehrig" Discussed on Baseball Tonight with Buster Olney
"Not that I'm a Yankee fan, but I know a game when I see it. And Paul O'Neill had game. All right. Because we haven't started the regular season. We're not going to start with a weekly quiz operated by you. I'm going to run it this week. I'm going to turn the flip the switch on you. I want to have you against Taylor and here's the trivia question. You ready, Todd? Let's go. Okay. Whose number was first retired by the Yankees? Was it a beloved manager Miller huggins who died in 1929? B, Babe Ruth, C, Lou Gehrig, G Hall of Fame pitcher, herb pennock. Again, which player, which person had their number retired first by the Yankees, Miller huggins Babe Ruth, Lou Gehrig, her pennock. I Taylor, I'll let you go first. Let's go with Lou Gehrig. Okay, Todd. Number four, Lou Gehrig. That's right. You both got it right. I was born in such that I could fool you, but both of you were totally locked in. Maybe we need to do this all season long. Turn the tables. It's a different kind of year. Who knows? Who knows? It does feel like it. And you know, Taylor's probably going to endorse me running the quiz because mine, they're going to be a lot easier, apparently, Taylor. Yeah, you're the new chief executive. You know, emergency powers, that's a thing that gets thrown around a lot these days. So oh my goodness. Oh my goodness. Well, in preparing the quiz for this year, I obviously need to face the fact that maybe Taylor is not the most passionate baseball fan in the world. No knock at you tailored it's just a fact. Buster, on the other hand, embedded in the industry for as many years as you have been, it would not be fair to ask certain questions of Taylor that I know buster is just going to know by rote. Color questions. I can't ask those, right? So I'm really between a rock and a hard place when it comes to putting this quiz together. But I have a master spreadsheet. I have already started to populate it with what I think are appropriate questions. And I, as I always say, every week, you got a one in four chance, right? 25%, that's pretty good. Exactly. Man, Sarah, you know, maybe we'll work Sarah in as well. Maybe that's Sarah versus Taylor at some point. She can she can step in. All right. Great seeing you. Welcome to 2022. Bleacher.
"lou gehrig" Discussed on The Business of Esports
"She does a great job every week. Great guests every week. And so highly recommend it. Jeff, I know how you're doing today, because you and I, my friend have spent the last three hours together. Yeah. I stepped up to the plate, you know, to record the podcast. We had an awesome guest. So you look forward to that. And yeah, I'm taking Jimmy's place. I think we'll announce it probably. If he's watching, I don't want him to see this live. But we'll break the news to him that I'm the new host. You can't take off in this business. Business is cutthroat. It's a dog eat dog world. You know, he's supposedly has COVID. And so, you know, it was his spot to lose there. Jeff, and you stepped in very nicely. So it's a great great segue. Tomorrow's episode of the podcast or the episode that drops this week. Chris Matthews was our guest from game rabble. A lot of interesting discussion around eSports coaching and their specific target demographic, which is younger and kids. So really interesting conversation there. And co hosted by none other than the juice himself. So you guys will get a little something different on this week's podcast. And I think you'll really enjoy it. Star wise says, finally, timed right to tune into one of these can't wait to take in some eSports wisdom. Star wise, thank you so much. We love having you here. So welcome. I don't know who this is, but says hello everyone looking forward to some hot takes. Hello, thank you, Robert says hello. Robert great to see you. Michael says hello, everyone. Michael great to see you. And there's the man himself. Chris. Who is the guest you have to look forward to on this week's podcast guys. So definitely go check out that episode when it drops this week. It'll drop tomorrow Friday as always. Just as a quick side plug, I also had Cecile Matthews on the meta woman podcast episode two to also talk about game rabble, so listen to both of them. Yeah, I love that idea actually. My listen to just one. Lindsay, they should just listen to all of them. Adam says, if Jeff replaces Jimmy, does that mean there's an opening? I mean, Adam, I like the way you're thinking is very cutthroat. And there might be, you know? How many games did Lou Gehrig replace Wally pep? You know, all took was one you just given opening and then you know it.
Mitch Albom Never Intended to Write 'Tuesdays With Morrie'
"Show. I have a guest right now. My bet is that you have heard of him, you may have read some of his books. His name is Mitch album. He is the author of a book called Tuesdays with Maury. I know you've heard of it. It was made into a film, a TV movie. It was on The New York Times Best Seller list for like four years. And speaking as an author, I want to say, I deeply resent you Mitch album. Welcome to the program. Well, outside of the resentment, thank you for having me on the resentment is bitter, but I'm gonna let it go. There's no reason to cling to bitterness. No, seriously, that is, as an author who is familiar with some of these metrics, that is an extraordinary thing, and the book that sits atop a bestseller list for years is extremely rare. The only one I can think of offhand is M Scott peck's the road less traveled, which is also a book about, hey, what's the meaning of life? So I want to ask you, first of all, you have a new book out. I want to mention that up front. And it is a novel called the stranger in the lifeboat. Is this your first novel? Oh no, no. I've written about 7 novels. All right. So maybe two 7th novel. But you're most known for Tuesdays with Maury. It tell the story behind that for people who are unaware. They still exist. Some people who are unaware of how that happened for you. Sure. Well, it was really quite an accident, so actually the fact that it stayed on those best sellers was for that long was even more remarkable because it wasn't ever supposed to be a book. I had seen my old college professor, Maurice Schwartz. On nightline with Ted cop, and he was talking about what it was like to die from Lou Gehrig's disease. And I had been very close with him when I was back in college, but then I had lost touch with him as I had gone on to chase my career and my ambition. And for 16 years, I never got back in touch with him and all of a sudden I saw him on television. Basically saying he had a few months left to live. So I went to go visit him. And one visit turned into two to turn to three, four, 5, 6. It was never supposed to be a book. Erika was just it was just him kind of counseling me on what's important in life once you really know you're going to die as he did and how you can change your life to live
"lou gehrig" Discussed on Aaron Mahnke's Cabinet of Curiosities
"And grim and mild. Our world is full of the unexplainable, and if history is an open book, all of these amazing tales are right there on display. Just waiting for us to explore. Welcome. To the cabinet of curiosities. America's national pastime has seen its fair share of legends. Greats like Jackie Robinson, Willie Mays, Ted Williams and Ty Cobb have left their marks, not just on baseball, but on the landscape of American sports. Yet, there are two players who have been named as legends despite suffering a few embarrassing losses at the heights of their careers. Specifically at the hand, well, the arm of one unsuspecting pitcher. The name Jackie Mitchell probably doesn't ring a bell even to the most Ardent baseball fans. Mitchell was a left handed pitcher for a minor league team in Chattanooga Tennessee. Before that, Mitchell grew up learning from some of the best pictures the game had ever seen. Dazzy Vance, who had played for the Brooklyn Dodgers in the 1920s, had once taught the up and comer, how to throw a sinker. There were also the kids around town who would all play ball together, giving Mitchell all the practice needed to take on the biggest names in baseball. Specifically, Babe Ruth and Lou Gehrig by 1931, Ruth was a star on the field and off. He'd already won three World Series with the New York Yankees. He'd been in a feature film, and he was doing some of the best plane of his life. And Lou Gehrig Ruth's teammate was right behind him. In more ways than one, where Ruth batted third in the lineup Gehrig batted fourth from extra base hits to total bases, Lou Gehrig's stats were often one or two places behind the babes, making the two players a powerful duo on the field. In 1931, Joe angle, formerly of the Washington senators, was looking for a way to boost ticket sales for his minor league Tennessee baseball team. It just so happened that the Yankees were passing through Chattanooga on their way back from spring training in Florida. They decided to play a few exhibition games against engel's team, the lookouts, which were sure to drum up business. After all, it wasn't every day that Chattanooga locals got to see Babe Ruth and Lou Gehrig play against their hometown heroes. And to really seal the deal, angle brought over his newly signed pitcher. Jackie Mitchell, to face the babe and the iron horse head on. Mitchell couldn't wait to knock Ruth and Gehrig for a loop, especially with the possibility of a big league career on the line. The date was set. On April 2nd, 4000 cheering fans filled the stands at engel stadium. The day before, reporters had interviewed Mitchell, who was quoted as saying, I'll do my best and will go out there with plenty of pep and with my mind made up on one thing to fan Babe Ruth. The pitcher took the mound, Ruth stepped up to the plate, a crowd roared. Mitchell through the first pitch as a ball inside a rough start. A second pitch flew over the plate, Ruth swung and missed. Strike one. Another pitch came sailing through and he swung once more. Strike two Ruth asked the umpire to examine the ball for any defects or signs of tampering. But the empire didn't detect anything out of the ordinary. Mitchell had smoked him, fair and square. Ruth angrily accepted the umpires ruling and got ready. Finally, the last ball sailed straight ahead, landing in the catcher's mitts as the great bambino swung for the third time. He was out. Much to the surprise of the crowd. He threw his bat on the ground and stormed off as Gehrig stepped up to the plate. And Lou didn't fare any better, swinging at every pitch and missing each time. Three strikes, and he was out. For one heavy hitter to strike out against a newcomer was a shock. But two, that was unheard of. Even more surprising was who they'd lost to. Jackie Mitchell wasn't just a minor league Newbie. Jackie Mitchell was an 18 year old girl. Now, some historians claim the whole thing was a setup from the start. After all, Joe engel's nickname was the baron of Bologna. He was known to pull all kinds of stunts to sell tickets to his games, including replacing his shortstop with a live Turkey. Pitting an unknown Mitchell against two willing participants in Ruth and Gehrig may have been just another ruse to get people in the seats. Others believe Mitchell really did strike them out. Neither Ruth nor Gehrig ever admitted to being in on it. She was young and inexperienced, so it was possible that they just didn't expect her to pitch the way that she did, and missed because of it. Either way, Jackie Mitchell died in 1987, believing that she had struck out Babe Ruth and Lou Gehrig. She was a legend in her own right, and an inspiration to women everywhere. This episode was made possible by Norton 360 with LifeLock. It seems like more and more getting what you need online as a tradeoff between convenience and privacy. Want to connect to public Wi-Fi? It might not be secure. Want 25% off a tropical vacation? You might have to give up a lot of your personal information to do so, like your email birth dates, phone number. Even your significant other's birthdays. Unfortunately, it's easy to be unsafe online, but now it's easy to help protect yourself. Norton 360 with LifeLock gives you powerful device security, a VPN to keep your Wi-Fi activity private. And identity theft protection to help monitor your info and alerts you to potential identity threats all in one. No one can prevent all identity theft or monitor all transactions at all businesses. But you can opt in to cyber safety. Save 25% or more off your first year at Norton 360 with life lock at Norton dot com slash cabinets. That's 25% off at Norton dot com slash cabinet. At the height of World War II, people all over the world were pitching in to support the war effort. Those who couldn't fight helped organize scrap metal drives welded airplane wings together and sold war bonds. Many of these jobs were done by the wives and mothers of the men fighting overseas. However, over 350,000 women served during the war, from the army to the air force. In fact, several women helped the allies win thanks to a particularly crafty secret weapon, one that the enemy never saw coming. Phyllis.
"lou gehrig" Discussed on Back To Work
"Possible merlin. Man thanks feels. Hang on the ed over. The ad is over yeah This is what it's like to have. My brain is all the terrible terrible jokes in the cracks in the interruptions. That i make your idea how many i don't even you're not even making ninety percent of them adjust like jazz. The shots don't take you know what i mean. Yeah yeah you gotta you gotta skate to where wayne gretzky's going that's right Let's see who. What is the. I came up with the monarch What what is the periodic table abbreviation for iron Something that he wouldn't expect is not an is isn't it. isn't it efi. yeah. I liked that one wants to say yes. I'll say what. Lou gehrig di of lou gehrig's disease that's correct also known as al ls. So here's what you remember. Lou gehrig was the ironhorse f. e. for iron. Ls for lou gehrig's disease fields us. Okay is that help at all. Yes the ironhorse. They call them now. What are they called. Cal ripken mr saturday night. No what they call him. Midnight special the midnight special. The high heard about the The midnight strangler feels Thank thank you thank you feels. It feels puck. i want to talk about. I was fifteen. I do before that. I had something funny. I had before that to go. Oh well you. I i i all i wanted to say was talking about. I was fifteen. But i have some tiny odds and infinitesimal sods but before we get to. The police continue well. Here's one here's one you'll like so I'm you know. I'm in this long process of educating children as they get older and growth. That is a long process and one of one of the classes that i teach them. It's called music appreciation. And so i've been teaching them about. There's film appreciation and movie appreciation and nothing else matters. That's the only thing that i teach and with the cork corcuera. Yeah that's your and so talking about pilates. Okay through through through music appreciation in those classes. We're exploring the sort of What what you would call like jam bands of the nineties fans that would get up and they would play music that you could argue that the music is divided into segments called songs but not really and similarly jam style bands. Lake the thing. Is you on a continuum you've got you've got totally improvisational stuff like especially in jazz. Almost totally improvisational but then gets something like fish or even early maybe rush. I don't know what we've got like now. I don't think they're improvising..
"lou gehrig" Discussed on Baseball Together Podcast
"Have this huge book full of details about players that have ordered which turning model in which weight and which length and all this you know all these little nuances and they said that they have been paying closer attention or anybody had any indication that something was wrong with lou gehrig then he would They would have known something was wrong because going back to look at his records you can see how he shortened and lightened his bat every year leading up to his relatively sudden the final year. That's crazy exactly. It's crazy and it was basically the coolest story ever i think. So but here's why it's the coolest story ever because the guy's still played baseball. Yeah he's still showed up and went to work every day he still put in his time. He's still got the at bats and what he decided to do was knowingly or unknowingly acknowledge that something was wrong and that he needed to adjust as many things as possible and one of the things adjusted was the tool. He was using at the blake. Yeah because he was swinging a freaking truck at one point and at that time it right exactly so it. So it gets lighter and lighter and lighter and a little bit shorter over time and they the guy who manages the book at the louisville slugger bat factories said literally said no. No no look. You can see it progressively. He gets weaker and weaker and weaker and then to perform at that level throughout. I mean this is what we're talking about is chronic resilience And i don't understand it. It's not at that level. It's insane like how much shorter and lighter did get. Was it like a couple inches by the end. There was like fractional it. No it was. It was like a full inch or so incheon change. If i remember right. I used to basically thirty three to maybe like a thirty one and a half right like it was at margin..
"lou gehrig" Discussed on GSMC Baseball Podcast
"Who pops out to shortstop one to eight still. After the top of the eighth now on the bottom of the eighth aroldis chapman is enters the game and he drills mickey mantle on the leg and then lou gehrig hits another two run home run to right field that makes the lead ten to one. That is nuts. Then babe ruth takes ball for eddie mathews ends up striking out swinging and then with one runner on yogi bear rounds out to a three six three double play less chance for the young guns here in the top of the night with colfax still on the bump and barry bonds flies out to deep centerfield mark maguire fouls out to third and that brings up buster posing ken. Griffey junior with two outs. And buster posey's lasers one into left field for a double griffey. Flies out to deep right field for outnumber three final score of game to ten to one. Ten hits the alzheimer's timers and an air by colfax. The young guns get one run on just five hits striking out six times for the alzheimer's they get like i said five runs on ten hits doubles by roger horns berry lou gehrig and hana swagger a triple by mickey mantle and two home runs by lou. Gehrig that was one heck of a ballgame. Also babe ruth got an rbi. In there mickey mantles mickey mantle had three to out rb. Sorry making it'll have a two-out rbi when he hit his triple lou gehrig technically head. Three two out rbi's today. That was one heck of a game. We're going to take a short break right here. And i know i went really long with this segment. But i still have five more games than i gotta get into. We'll be right back. Want.
"lou gehrig" Discussed on PhotoBiz Xposed
"The thing about grief is that it's just love another form and so you know my love for schuyler will never go away and therefore my grief will never go away either. Because i can't get for back. But i found that it doesn't always have to be so painful. Feeling those emotions and letting them come up and out really helped me heal that. Kind of like robbery's pain where i just felt. My world was collapsing. You know and i was able to. You know with the love and support of others. In addition to feeling all of those feelings i was able to start picking up some of those shattered pieces of my heart and learning. how to rebuild heller. Was this ten years ago. Try and do you have other children. Are you still married. I am still married. Remarkably it does take a huge toll on her relationship and my husband. And i worked through some really really low points and we are still married. We don't have any other children so the condition that she had is genetic and so it's called spinal muscular atrophy or estimate for short and it's very similar to lou gehrig's disease. There is a treatment. But they're still no cure and at the time that we had her. There is no treatment even and so yeah one in forty people are carriers most unknowingly. My husband and i are both carriers. We had no idea. and then yeah every child. We have has a significant chance of having estimated as well so we've just decided to kind of stay no entire tubes in you know potentially opt in the future but we're in no rush show show and the reason i ask about your marriage and other cases because first of all i think the listener will be wondering the same thing. I know that when you were talking about going through that grief process particularly that first year like you said you have to focus on yourself and getting through that. I'm sure your husband went through the same thing and it must be really difficult not to. I don't want to say blame each other but getting each other's way. Yeah and i've spoken with so many moms have other kids when they lose a child and it's like you know it's challenging either way in it's really hard to compare situations because it's so different like i was able to lay in bed and not get out of bed until like my dog needed to go out and just flakes be depressed and later on the house and not have to take care of anyone else right like i didn't have that responsibility but in being alone yes i didn't have kids to take care of but also like kids can be such a beautiful distraction to like. Really pull you back into the present to say like i need you right now like i need you to feed me. I need you to change me or whatever it is and they can pull you back in that that present to to function again and so but at the same time like when you need to just like lay and do nothing like. There's a kid needing you you know and sometimes multiple kids and i you know i. I think it's hard no matter what situation you're in for show for show with photo's that you'll gifted by your friends. I'm guessing though machinery though with a professional photographer and so how long before scholars passing with i taken the first session. We had as when she was like. I wanna say six months and then when she made it two year so the doctors fullest likely not see her first birthday and when we made it to a year the attack for that they had wanted to come back into another session breast in so we ended up doing not session when she was sixteen months old but she was having a bad day not feeling well and just kind of cranky and so sad because we didn't get any smiles out of her or anything and then she passed away at twenty one months old and so so yes we have those two sessions and then we actually had a another session early on when she was three months old because she had to go through her first surgery and the doctor's basically told us that we can't guarantee that she's gonna come out alive because she's such a fragile baby and so i just asked a friend who does photography as well to just come over and do a few photos in case she doesn't make it out of surgery like i wouldn't have anything and so we ended up with three total professional portrait sessions of our family together which is just such a so. I feel strange in this question. But you have three photo sessions. It sounds like the middle photo session was the best one as far as the photos go. She sang lock. She is happy. The photos a gripe everything was looking good. So i'll tell you the ones you gravitate towards. Now yeah the three-month ones were also beautiful and she was so happy. Then yeah so. Those earlier sessions are the one that like i have printed on my wall. You know and like framed in my house but there are some really sweet moments in that the third session that the photographer captured who moments where she was like fluffy and i was trying to console her like we just leaned down and kissed her face her We ended up. Just we kind of took a picture of all of our feet to get married because it was kind of weird but i am really weird toes and so like most people have like this pretty arch of toes that lake go down in a nice pretty arch and like all of my toes are like straight across and then it drops down to my pinky toes. I've linked very square looking. Does and the joke was schuyler looked so much like my husband that i was like..
"lou gehrig" Discussed on The South Florida Morning Show
"Olympics. Simone biles our last hope actually. Nbc's last hope for ratings. She's out she's been the reason why they were first reported some kind of an injury in the team competition and may be something more than that now. They said originally that she got hurt on the volt and that she was seen leaving with ice on her ankle and her trainer then it turned into. She was seen walking away with a bag her gym bag and her trainer. Then it was said that wasn't an injury it was. Maybe she just couldn't handle it anymore. Got the pressure got to her and she was like i'm done and then she took herself out of the competition. There's like depending on where you go. There's a different story is a lot a lot of misinformation out there. I i hope. I mean hope. Either way she's okay but that stinks diener. Did you hear otherwise. I just saw something interesting. Here with mike tirico. Where he's talking about the her trainer. I guess being quoted as saying that she's physically. Oh alright so well that would tell you then. That would only leave one thing right well. Yesterday we talked about her comments. She did an interview. And i don't know if it was nbc. Or who did the interview with and they said are you ready. And she said for the first time in my life. I feel like i have. I'm carrying the weight of the world. And we both said bill. And i said that's not a good thing to be saying when you're going in competition that follows up with you. Know they always do the the big sit down interviews and What's her name hoda. There did one way. I saw this on sunday night. A pre-recorded interview choose talking about the long-term effects that whole larry a niles. What's his name nassar. Yeah the trainer. The creepy trainer the effect long-term effect. That's still has on her show that he even know he was the team doctor. Yeah for all of them kata michigan. Thank you very much. There might be a lot old scars there. I don't know what's going on but It's a shame. It's a really yeah. Hopefully she's going to be okay. So they put in this jordan. What's his girls named. Jordan jordan child's sheils has taken her place and i. It's a tough. Those are tough shoes to fill. Be like lou gehrig filling in for wally pip. Right into the new legend. Who said that to somebody. You told me that. Story the next wally pip and i was like bill. Chick said it to element to Wes welker about women. he wasn't in a preseason game. Is wally pipped. Guy took a day off lost his job. For what was it. Two thousand twenty five hundred games lou. Gehrig that's right when simone biles a little different. We hope she's okay. Wow yeah that's true. I hope so too. There was a great story coming out of the olympics. actually one interesting thing a swimmer from alaska. That in itself is an oxymoron. I two gold a swimmer in alaska. Let's start there. That was something positive coming out of these games. Anyway we get some headlines all coming up next these cell florida morning. Show this janna.
"lou gehrig" Discussed on The Bronx Pinstripes Show - Yankees MLB Podcast
"I <SpeakerChange> closed in <Speech_Music_Male> saying it <Music> might have <Speech_Music_Male> <Speech_Male> been given <Speech_Music_Male> a bad grade <Speech_Music_Male> <Speech_Music_Male> but i've got an awful lot <Speech_Music_Male> to live for <Speech_Music_Male> thanked. <Speech_Music_Male> <SpeakerChange> It <Speech_Male> wasn't <Speech_Male> a dry eye in the house <Silence> including gehrig's <Speech_Male> the <Speech_Male> new york times. The next <Speech_Male> day wrote <Speech_Male> the vast gathering <Speech_Male> sitting in absolute <Speech_Male> silence for a longer <Speech_Male> period than perhaps <Speech_Male> any baseball <Speech_Male> crowd in history <Speech_Male> her gary himself <Speech_Male> deliver as amazing <Speech_Male> valedictory <Speech_Male> as ever came <Speech_Male> from a ballplayer. <Speech_Male> It was <Speech_Male> an amazing speech <Speech_Male> and not just because of <Speech_Male> the circumstances <Speech_Male> was a speech <Speech_Male> about appreciating life <Speech_Male> but being <Silence> grateful for what you have <Speech_Male> gehrig <Speech_Male> wasn't asking for <Speech_Male> sympathy or for prayers. <Speech_Male> He simply <Speech_Male> stated what his family <Speech_Male> the fans <Speech_Male> baseball <Speech_Male> and what the day meant <Speech_Male> to him. Gehrig's <Speech_Male> life was baseball <Speech_Male> as a young kid. <Speech_Male> He played in the sand <Speech_Male> law. And in the streets <Speech_Male> of manhattan. <Speech_Male> He played as a college <Speech_Male> athlete at columbia <Silence> university <Speech_Male> as a pro. <Speech_Male> We played in yankee <Speech_Male> stadium. Baseball's <Speech_Male> cathedral <Speech_Male> he made his major league debut <Speech_Male> at the age of nineteen. <Speech_Male> He won <Speech_Male> his first. Mvp award <Speech_Male> at the age of twenty <Speech_Male> four by <Speech_Male> age thirty. He had amassed <Speech_Male> over. Three hundred <Speech_Male> home runs <Speech_Male> by the time he was thirty. <Speech_Male> Five one six <Silence> world series. <Speech_Male> His departure <Speech_Male> from baseball and from <Speech_Male> the world happened so <Speech_Male> quickly. <Speech_Male> On april thirtieth <Speech_Male> nineteen thirty nine. <Speech_Male> Gehrig went hitless <Speech_Male> against the senators <Speech_Male> in the two thousand <Speech_Male> one hundred <Speech_Male> thirty consecutive <Speech_Male> game. He played <Speech_Male> before their next <Speech_Male> game on. May second <Speech_Male> gary benched <Speech_Male> himself. <Speech_Male> He told mccarthy it <Speech_Male> was for the good of the team. <Speech_Male> Garrick had been <Speech_Male> hitting just one forty <Speech_Male> three that season <Speech_Male> as the illness began <Silence> to break down his <Speech_Male> body at <Speech_Male> the ceremony. When mccarthy <Speech_Male> spoke <Speech_Male> he said <Speech_Male> lou. What can i <Speech_Male> say except that. It was <Speech_Male> a sad day in the life <Speech_Male> of everybody. Who knew <Speech_Male> you when you came <Speech_Male> to my hotel room <Speech_Male> that day in detroit <Speech_Male> and told me you were <Speech_Male> quitting as a ballplayer <Speech_Male> because you felt <Speech_Male> yourself a hindrance <Speech_Male> to the team <Speech_Male> my god man <Silence> you were never that <Speech_Male> <Speech_Male> lou remained with <Speech_Male> the team as captain <Speech_Male> but never again appeared <Silence> game after april <Speech_Male> thirtieth and <Speech_Male> early june while on <Speech_Male> a road trip in chicago <Speech_Male> he visited <Speech_Male> the mayo clinic <Speech_Male> in minnesota <Speech_Male> after extensive <Speech_Male> tests he was diagnosed <Speech_Male> with ls <Speech_Male> june nineteenth <Speech_Male> nineteen thirty <Speech_Male> nine his <Silence> thirty sixth birthday <Speech_Male> <Speech_Male> after his public a by <Speech_Male> july fourth. <Speech_Music_Male> The hall of fame inducted <Speech_Music_Male> garrick by <Speech_Music_Male> special election <Speech_Male> to commemorate <Speech_Music_Male> the year in which he achieved <Speech_Music_Male> his record. <Speech_Music_Male> They're talking about <Speech_Music_Male> his consecutive games <Speech_Music_Male> record. Of course <Speech_Male> the writers <Speech_Male> felt he needed to be <Speech_Male> enshrined while he was <Speech_Music_Male> still alive. <Speech_Music_Male> Gary passed away <Speech_Music_Male> less than two years after <Speech_Music_Male> his famous speech. <Speech_Music_Male> The yankees <Speech_Male> honored their captain <Speech_Music_Male> with a monument and centerfield <Speech_Music_Male> that year. <Music> Nineteen forty <Music> one. <Music> <Advertisement> Thanks for listening <Music>
"lou gehrig" Discussed on The Bronx Pinstripes Show - Yankees MLB Podcast
"Fourth of july. Everyone this is a throwback to the a brief history episode. I did last summer about lou. Gehrig's luckiest man speech this year and will be announced that from here out june second. We'll be lou gehrig appreciation day. Why june second on that date in one thousand nine hundred eighty five. Gary became the yankees starting first baseman. Wally pipping wally pip. Sadly it's also the day in nineteen forty one that he passed away. It's great that there's now a day honoring lou also raising more awareness for ales. And frankly i don't know what took so long but that's not what we're here to talk about today. July fourth nineteen thirty nine a sellout crowd watch the yankees. Play to baseball games against the washington. Senators yes it was a holiday in the games probably would have been packed anyway but the sixty one thousand eight hundred and eight people who went to the yankee stadium that day went because it was lou gehrig appreciation day two weeks prior garrick was forced into retirement. Two months prior. Gary played his last game. He was only thirty five years old after his sudden retirement and news of his illness was known. Reporters started to suggest that the team and the league should do something to honor the ironhorse. A ceremony at the all star game was considered but ultimately the team chose intermission of the july fourth doubleheader. Derek was honored on the infield diamond for over forty minutes. It was the first ceremony of its kind in baseball. His number four was retired. Also the first time a uniform number had been retired. Technically gehrig's number wasn't officially retired by the yankees until january. Sixth nineteen forty when he was inducted into the hall of fame. But you may also see this date. July fourth nineteen thirty nine as the date has number was retired new york city mayor fiorello laguardia and postmaster general james. A farley attended wally pip. Who garrick replaced in. The lineup was their teammates from the nineteen. Twenty seven. Murderers row yankees. Were also there. Joe mccarthy and babe ruth were among the few who gave a speech loose stood there in full uniform listening to the speeches with his hat in his hand the talked about his consecutive game streak and how he was such a clutch player. A great leader and teammate lewis. Bow his head and shook hands and appreciation from looking at the pictures and watching the video footage. You can tell that. He was uncomfortable with the whole thing. Garrick was apprehensive about attending the ceremony. In the first place he was a shy reserved. Guy as described in the biography luckiest man. Gehrig looked as if he couldn't wait to get it over with. He removed a big white handkerchief from his back pocket and wiped his tears. He shifted his weight from left to right and stare at the ground. Lou didn't want his peers in the fans to see him in his weakened state people who knew him say he eight years in just the two weeks since they last saw him. Travelling with the team he lost weight and motor functions had started to diminish already. He received tons of gifts a silver service. Set from the yankees front office a fruit bowls candlesticks from the new york. Giants silver pitchers and platters a fishing rod and tackle rings a tobacco stand and a scroll but his most cherished gift the only one he carried with off the field was given to him by his teammates. It was a silver trophy engraved with all the names of the current yankees and a poem written by sports columnist. Joke karen cure later said it was bill dickey who orchestrated the gift and asked him to write the poem and karen was the perfect medium member to write this because he and liu were neighbors and friends lewis grateful but he didn't wanna make a speech when the mc told the crowd that garrick appreciated their support but asked not to speak. They started to chant. We want lou. We want lou. They weren't gonna let him get out of there without addressing the crowd then manager. Joe mccarthy said something to garyk that changed his mind. He ushered them to the microphone. Where lou pause for a minute thinking about what he wanted to say. He took a deep breath and then gave baseball's gettysburg address. We've been usaa insurance to help you save. Take advantage of discounts when you cover your home. Answer ride discover how we're helping members safe at usaa.
"lou gehrig" Discussed on ESPN Daily
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"lou gehrig" Discussed on ESPN Daily
"And a bigger part of this sports feature so on october. Twenty first of two thousand and twenty. It is decided by the league. Officially lou gehrig day will take place on june second every single year from this day forward. June second being the day when garrick began his consecutive game streak and also the day he died so every lou. Gehrig's day from now on each home club is gonna display four s. logos on their jerseys commemorating gehrig's uniform number four commemorative patches and wrist bands and participation from the ails community with first pitches and national anthems across the sport which is exactly what be weighing had worked for jeff. So where was he when he heard the news. That lou gehrig day was gonna be a reality. Be wayne was at his house. And you know stacey says. He just had this energy about him. Brian was at that point. Pretty much on a ventilator almost twenty four hours a day. We were sitting in this very room that i'm in now and i remember him saying we did it. He was so excited about this. You know he was gonna live to see this day happen. And it's about somebody who he never met and it's four people who he may never meet and he still did it seeing that all the way to the end seeing that through and seeing it happen. I think brian wayne gallon the sort of peace that all of us are looking for in our lives. What happens the next day. Stacy that morning. She's a fundraiser for college and she had gone to nashville to have a meeting and she got a call from be wayne's caregiver. I left to go.
"lou gehrig" Discussed on ESPN Daily
"Everything to capture it goodyear more driven all right jeff so in two thousand and seventeen. Brian be wayne gallon. Thein is given the worst diagnosis imaginable. A ls it is a disease with no cure. He has a wife. he has two young kids. So what does he decide to do. About baseball is still at the forefront of his mind now because remember he understands. He doesn't have a whole lot of time to live. So he's going to focus on the things that really do matter to him on his wife and on his kids and on this game that confuses him a little bit because just once before pablo back in two thousand nine. There was a man named michael goldsmith. He was a lawyer and an aol advocate and he convinced. But see the commissioner at the time to honor lou gehrig on july fourth that year and at fifteen stadiums across the country. They did just that. It didn't happen in two thousand ten and two thousand eleven beyond. It was a one year thing and brian. Wh gallon thein saw that and thought to himself. How can major league baseball. Not offer lou gehrig. It doesn't make any sense. And so he sent the text message to his friends. Adam wilson who has ale s chuck average stroke whose mother patty has as semtex a text saying basically like why is there a luger daylight jackie robinson day and we said that's an interesting idea. Be weighing you know. Seems like a big big ask. But let's try to do it. This was such a classic. Be wayne thing to do. He's the guy who says. Hey guys why don't we just go tell major league baseball to have a lou gehrig day. Let's try and do something that nobody else has done. That is wrapped like a mummy in red tape. That has such little chance to actually come to fruition. Because who's gonna stop us from doing what it lou gehrig mean to be wayne personally. He was inspiration. He was someone who lived the right way and he was someone who died the right way and a lot of times with s patients. What they want is dignity in a disease that tries to rob it and i think be weighing saw how lou gehrig died and said to himself. If i'm gonna go. I wanna go the same way. I wanna go spending time with people that i love and doing the kinds of things that i believe argue to have a long lasting impact. So how does be wayne start this particular mission the mission of establishing a lou gehrig day you know it started with the tax message and adam wilson and chuck cab or show or like laura b. Wayne let's get at it. The colorado rockies are the i team on board because their first baseman san hilliard's father jim was diagnosed with l. s. So he's in the oakland a.'s. Are and because they're outfielder. Stephen scotties mother gretchen was diagnosed with l. They get eight teams and it stalls and be wayne does not take kindly to this stall. You wouldn't take no for an answer. He said it's going to be easy when they hear our story. They're going to have to say yes quite honestly. There were days when i would be frustrated because we're at the dinner table and he's on an ao less call talking about lou garrick day. Be wayne was mystified when they were standing there with eight team saying how are all thirty teams. Not jumping at doing this. So they've hit this wall they have just eight of the thirty teams on board. How do they get from there to a place where the whole entire league buys into this idea. A stroke of luck. It was october of two thousand twenty and they were desperate be wayne had gone from not being able to walk to not being able to talk to being on a ventilator for twenty three hours a day and people who have ale s like to say we work at the speed of al s which means there's no time to wait around for anything in the desperation got to the point. Where adam wilson started guessing. Email addresses went looked at an organization's domain and he guest okay. Is it first initial last name. First name dot last name and when he tried to email a man named eric call. Who's the president of the arizona. Diamondbacks what he didn't realise was. Just how fortuitous. That email was going to be. Derek hall had lost friend to and had lost his grandfather to aol less and so immediately der calls. I thought was. Why isn't this dot. I got so excited. When i saw lou gehrig in the email that i immediately robak into guys. Let's do this. Let's figure out how to get this done in. And so he talked. Dave saint peter. The minnesota twins president and sam kennedy. The boston red sox president and together at three o'clock in the afternoon on october nineteenth. They sent out an email to executives around baseball looking for their support in creating this lou. Garrick day dare call sends out the email five minutes later. Randy levine from the new york. Yankees writes back. I support it. And then the dodgers come in and stan cast and says the dodgers and i are on board and then derek jeter who owns the miami marlins comes in and says you have my support and that of the marlins and the emails just keep rolling in finding consensus in baseball. Pablo is an impossibility. You could ask the thirty baseball teams. What does one plus one equal and one of them would be like nuts. Three like he can't get all thirty baseball teams on the same page with anything and within twenty four hours all thirty major league. Baseball teams had agreed. That lou gehrig day had to become a reality. Had to be a part of this sports present.
"lou gehrig" Discussed on ESPN Daily
"He was your imposing incredible. Left-handed slugging new york yankee guy who was mashing.
"lou gehrig" Discussed on NewsRadio WIOD
"To see exactly what they have and what it's worth, and a lot of people ended up putting them on those auctioning sites, and this collection includes cards with Ty Cobb, Lou Gehrig, Honus Wagner. There's another Mickey Mantle card from 1952 near Perfect that's expected to go for $1.2 Million, and they've got boxes of cards from tops in the 19 eighties that haven't even been opened yet. So there it's really tough to evaluate this whole collection and some of the cards go back like well, over 100 years, right? Yeah, There's a 1916 rookie Babe Ruth card when he's in his God less ID Red Sox uniform. God. Blessed Red Sox is the New Englander. My great uncle. Got a hit off Babe Ruth back when Babe Ruth was a picture. Is that true? Yeah, that's kind of cool. Started during the industrial leagues in the Northeast back in 19. Oh, wait or something. Now you mention the Babe Ruth card, the 1933 that they think is going to bring in over $5 million, but several other cards air going to go for over a million. They think Yeah, that Mickey Mantle. One is really getting a lot of the attention. You know anything with the MC. I's gonna get a lot of attention, especially from New York. Collectors on this really was a family affair. You know, it wasn't just something he was doing secretly in the garage. It really get involved his son in this and making all these trips to the collection collectible conventions on again. It was a 40 year. Passion for Just the right time. Yeah, just the right time. I think they just downsizing and trying because some of these cards were kept in his medical offices. Well, so they had to clear out that office and now I just feel that this is the time Tomo let other people share in it as well. You know, the widows said that you know, if other people can find some of the happiness it gave him then then that would make her happy. $20 million doesn't hurt either The auctions all taking place online, right? It's all gonna start online Memory Lane is the name of the auction company. If you google that if the auction starts June 21st, so a month from today, all right, Well, I appreciate it. Stay safe. Enjoy your weekend. I'll talk to you on Monday. Thanks, Manny. Sounds good. All right, 6 26 on NewsRadio, 6 10 W. Coyote and Erica Rodriguez joins us with a look at sports and a big night for the cats. Itwas Manny after coughing up a two to nothing lead, allowing five second period goals. The Florida Panthers rally from a two goal deficit to force overtime where Ryan Lambert's game winner six minutes into the extra session lifted the cardiac cats to 65 victory. Pulled them within two games to one in their first round, serious with the Lightning for Long Burger was his first shot on goal in this series in his first playoff hole in his career. It's also the first overtime goal for the franchise since Mike Huff and Dave Lowry lit the lamp with the game winners in 1996 game for in this Syriza's tomorrow at noon in Tampa. And Sandy L. Contra bounced back from the worst performance of his career, throwing six shutout innings with nine strikeouts, combining with three relievers on the three hits, six to Nothing win in Philadelphia tonight, Miami opens a home stand with no mask restrictions wearing the uniforms of the Cuban sugar kings while doing the Mets and a three game Syriza. George Holloway expected Get the start on the hill pregame coverage on our sister station. I'm 40 wins. Against at 6 49, Erica. Thank you very much. 6 27 were three minutes away from you. Next live check on traffic. A news radio 6 10 w y o d like a cowboy, please. There's no time like a couple of time in the way like the cowboy way. Have a gavel account today. Yeah, When you're home crowd boys contained that cowboy ground. No way, like the cowboy way have a cowboy candidate here. Like they have a big time. Try the new Big Sky burger every way. Rogers restaurants. It's a quarter pound burger with Smithfield pulled pork your battered on your ing's American cheese in spicy barbecue sauce on.
Major League Baseball to hold first Lou Gehrig Day on June 2
"Garak joins Jackie Robinson and Roberto Clemente as players who are honored throughout the league I consider myself the luckiest man on the face of the earth June second marks the ninety sixth anniversary of when Gehrig started at first base for the New York Yankees in place of Wally pipp starting his record streak of consecutive games played June second was also the day in nineteen forty one Gary died at the age of thirty seven Amiot trophic lateral sclerosis or ALS I might have been given a bad grade but I've got an awful lot on June second each home team will have for a LS logo's in ballparks to mark Eric's number for money will be raised to fight ALS also called Lou Gehrig's disease I'm at Donahue
Pat Quinn, co-founder of viral Ice Bucket Challenge, dies from ALS at age 37
"The A L S Ice Bucket Challenge. Has died. Pat Quinn died at the age of 37 yesterday after seven years with the disease. Quinn and the late Pete Frates started the challenge after being diagnosed with a L S, which is known as Lou Gehrig's disease. The ice bucket challenge raised over $250 million Since it took social media by storm in 2014. Those of you do not know
Pat Quinn, Ice Bucket Challenge co-founder, has died at age 37
"J. Powers, Fox News Another co founder of the Ice Bucket Challenge, has died. Pat Quinn, motivational speaker and co founder of the Ice Bucket Video Challenge for a less died Sunday morning at age 37. He battled Amy a traffic lateral sclerosis, often called Lou Gehrig's disease since diagnosis in 2013 the video challenge taking social media by storm in summer, 2014. Quinn talking to Fox News radio in 2015 disease that has no hope at the moment, but The ice bucket challenge is revamped that outlook the challenge so far raising more than $250 million worldwide. Currently, there is no cure for a less a fatal progressive nervous system disease, which impacts nerve cells in the brain and spinal cord, causing loss of muscle control.
Pat Quinn, Ice Bucket Challenge co-founder, has died at age 37
"And another co founder of the Ice Bucket Challenge has died. Pat Quinn, motivational speaker and co founder of the Ice Bucket Video Challenge for a less died Sunday morning at age 37 He better of India Tropic lateral sclerosis, often called Lou Gehrig's disease since diagnosis in 2013 the video challenge taking social media by storm in summer, 2014. Quinn talking to Fox News radio in 20. 15 disease that has no hope at the moment. But the Ice bucket challenge revamped that outlook, the challenge so far raising more than $250 million worldwide. Currently, there is no cure for a less a fatal progressive nervous system disease, which impacts nerve cells in the brain and spinal cord, causing loss of muscle control boxes.
Pat Quinn, Ice Bucket Challenge co-founder, has died at age 37
"Co founder of the ice bucket Challenge for a less died this morning at age 37 he better Amy O Tropic lateral sclerosis, often called Lou Gehrig's disease since diagnosis in 2013, the ice bucket video challenge taking social media by storm in summer. 2014. Quinn, talking with Fox News radio in 2015 is great for the A L s community. We really needed a new sense of fight new sense of hope. So far, the challenge raising more than $250 million Worldwide.
Co-founder of viral ALS Ice Bucket Challenge dies at 37
"The Ice Bucket Challenge for a lesson. This morning at age 37. He battled Amy Oh traffic lateral sclerosis, often called Lou Gehrig's disease since diagnosis in 2013, the ice bucket video challenge taking social media by storm in summer. 2014. Quinn, talking with Fox News radio in 2015 is great for the A list community we really needed. A new sense of fight new sense of hope. So far, the challenge raising more than $250 million Worldwide. America's listening to
Mind Over Body Cure
"Well, we've heard quite a few people on this show and others claim that they have thought themselves well, even in the face of death, but what about those people who do get sick and do get worse and die. Are they being made to feel guilty for not thinking themselves well well. My guest today are on opposite sides of this mind over body debate. Doctors don't know why my first guest is alive Lynyrd, borden says He. He changed his attitude. Imagine summarize warriors fighting the cancer in his body. A month later, the cancer was gone my next. Gus was told she had eighteen months to live if she did not have chemotherapy for her breast cancer Jane, Griffiths says she refused the treatment ten years later. She is still alive. My next guest wrote one of the most popular mind over body bestsellers. Dr Bernie seagulls love. Medicine and miracles explains his experiences with. With what he calls exceptional patients who hill themselves in the face of death. My next guest is a doctor who totally disagrees with Dr Segel's philosophy Dr Shirley new says sick. People are being made to feel guilty if they don't heal themselves, and there is no proof whatsoever that any of this works Dr Newlyn is author of doctors the biography of medicine. My next guest got so tired of people telling him that his severe backache. Backache was his own doing because of a bad attitude and stress. He wrote a column in Newsweek. Magazine to complain about it. Meet Rabbi Benjamin Black and my last guest says when she was diagnosed with Lou Gehrig's disease, people wanted her to try acupuncture and Yoga and love to get well and Spain says she live as long as she can, but she is also planning her death. Welcome all of our guests to the show. Start with you. I'll start with you. Because is where we got the idea to do the show from that column that you wrote in Newsweek magazine. What happened? I suffered from a herniated disk and I was just looking for some sympathy. And, then I suddenly realized that there was a psychological change in our society. and. Everybody kept saying to me. Why are you doing this to yourself? You must be the victim of self induced stress. And what really got me upset was that I recall the friend of mine who had died of cancer. who was able to deal with the reality of sickness? But couldn't cope with the fact that throughout the last days people made him feel as if he was the guilty one because he didn't obviously want to get well strongly enough because he wasn't trying hard enough, and he would cry to me. Does this mean I'm failure? What I'm saying is that there's an extreme position today I grant of course that there's a great deal to mind body relationship I grant as well that there is such a thing as love, medicine and miracles. What I think is wrong is I believe is a rabbi that we pray for miracles, but we don't expect miracles and when they don't happen, say that anybody who isn't well must be guilty himself. Don't blame the victim. Victim. Do you think Dr Newland this is making? People feel guilty as they die well. There's no question about that. That's really not my problem with Bernie's propositions. My problem with Bernie's propositions has to do with the aura science that he puts around them, in spite of the fact that what he's actually done is to take an enormous leap of faith, which of course is the secret of it all an enormous leap of faith from certain experiments, which show something that we all agree on that. There is a psychological factor that involves the immune system I don't think any sensitive physician physician with any experience could possibly disagree with the concept that patient state of mind is very important in their illness. But along comes Bernie, and says poof. The mind controls the immune system direct quote, the only quote I memorized from the book burning so that I could use it today. There's no evidence of that, and as long as people continue to believe with their minds, they can control their immune system there believing something that they simply can't do. It's like getting high LSD and trying to jump off a roof and fly, but you yourself just said that it's an enormous leap of faith and suppose it does suppose it does control the immune system, but there is no proof that it does. It's not a question of there being no proof that it does or does not. It's a question of our already being so close to understanding the various factors that do control the immune system that we know that the mind, the conscious mind is only one small factor. What actually happens is that whether we develop immunity to something whether we can control the disease process has to do with three systems in our body.
Report: 34 Used Vermont Aid-In-Dying Law Over 2 Years
"People in Vermont are now taking advantage of what is known as Vermont aid in dying law the report just released founder of the thirty four cases twenty four were people suffering from cancer for we're due to Lou Gehrig's disease a LS three would due to degenerative neurological diseases and three would do to other events Vermont law requires the health department to release the report every other year with statistics on how many people took advantage of the law to help end their
A final chilly plunge for man who boosted ALS ice bucket challenge
"Dead supporters of the frailties take one last chilly plunge for the former college baseball player whose battle with Lou Gehrig's disease helped inspire the ALS ice bucket challenge Freddy's family saying the eighth annual plunge repeat at a beach in Gloucester will be
Last Fundraising Plunge for Ice Bucket Challenge Inspiration
"News today marks the end of a frigid and very successful fundraiser heat Freddy's battle with Lou Gehrig's disease helped inspire the ALS ice bucket challenge supporters taking one last chilly plunge for the former college baseball player the phrase family says Saturday's annual plunge for Pete a good harbor beach and Gloucester Massachusetts is the last the former Boston College baseball player lived in Beverly a suburb north of Boston he died December ninth after a seven year battle with a alas or any atrophic lateral sclerosis the ice bucket challenge went viral in twenty fourteen raising more than two hundred million dollars for
Pete Frates, Who Promoted the Ice Bucket Challenge, Dies at 34
"He was the former college baseball star who is credited with raising hundreds of millions of dollars for ALS Freddie's died this week at the age of thirty four British grew up in suburban Boston where he excelled at sports eventually playing so our field for Boston College in playing baseball overseas after returning home he was diagnosed with a LS also known as Lou Gehrig's disease back in twenty twelve when he was just twenty seven two years later Frehley's championed this the ice bucket challenge became a viral sensation with celebrities an entire sports teams taking part two hundred and twenty million dollars it's been
Ice bucket challenge inspiration Pete Frates dies at 34
"His family says Pete Freddie's died peacefully in Massachusetts the former college baseball player was diagnosed with Lou Gehrig's disease in twenty twelve the ice bucket challenge got started in twenty fourteen Brady says family got involved the challenger exploded on social media I am doing this in honor of key phrase videos were posted online celebrities took the ice bucket challenge including Donald Trump before he became president it raised about two hundred twenty million dollars worldwide feed a LS in a twenty twelve interview Pete Frady said the man upstairs has a plan for me there are people out there that don't have my support system or my advantages and I want to help them I'm a Donahue
How to Look Forward to the Next Recession
"Welcome to the NBA show. Your Business gets better with every episode. That's why we deliver daily ten minute business lessons for the real world. I'm your host your coach. Your teacher Turow Mars and home. I'm also the CO founder of the Hundred Dollar Mba. A couple of visits training and community online and each episode is a guest teacher episode. Today's is guest is Jonathan slain. And he'll be teaching you how to look forward to the next recession. Jonathan's lane is the founder of recession DOT COM amazing eurorail author keynote speaker then thought leader when it comes to preparing your business for the recession no fear it just be prepared. It's just a matter of time time for the next recession. Recessions come in different forms as Jonathan will explain but the most important part is being prepared being ready so you can actually grow intercession. Jonathan has a lot to cover in today's lesson. So let's get into it. Let's get down to business. The show comes from Amazon. Logistics Amazon Logistics has a new program for leaders who want to build their own a full time package delivery business. Get access to Amazon's logistics training and technology and start building a team of motive drivers in your community to learn more about becoming an Amazon Amazon delivery service partner go logistics dot Amazon Dot Com ups and downs in Your Business in the economy are inevitable than those who are prepared for those who are able to not only survive but strife we brought on Jonathan slain to show US exactly how he shares his own personal story ory on how to actually thrive in a recession. How to be prepared to make sure you're not caught off guard so I'm gonNA pass it to Jonathon now? The cheese you his guests lesson. But I'll be back with my takeaways and to wrap up today's episode so for now taken away. Jonathan Buckle up. My name is Jonathan Jonathan slain in today. I'll be teaching you how to look forward to the next recession. It's time to rock my story. Is that right before the great recession in in two thousand eight I partnered with my brother in law to start opening up gyms fitness businesses. You know like personal training studios. We open new locations locations and we grew very fast. Our studios achieved new franchise records every year. We have the most personal training sessions ever in the history of the franchise is we had the most locations ever in the history of the franchise. We couldn't miss. We grew and grew and grew that is until we ran into into the great recession. Looking back I'm GONNA let I'm not this audience in on a little secret. Nobody wants to pay for personal training training in a recession and worse I didn't have a plan for what to do when the recession hit so I spent the first couple months of the recession curled up in the fetal position in the corner of my office and the other hand Paul My business partner and Co author who I wrote rock the recession with. He had a plan for the recession and he was looking forward to it. He bought a company and he did very specific things to grow at spectacularly using the downturn is fuel that led to his American Dream Exit poll had picked the HVAC business because he knew that he could leverage HVAC service in a recession. In contrast contrast I was in the personal training business because my brother-in-law happened to be a fitness fanatic and then ended up borrowing a quarter of a million dollars for my mother-in-law our law in order to help us survive the recession and the worst part is I'd ending abroad of the money. All at once I borrowed at twenty thousand dollars at a time. So Oh you do the math. That's twelve phone calls groveling for money. Now I've paid my mother-in-law back since and now on a mission to make sure that nobody has to borrow money from their mother in law in order to survive the next down term. You know right now. The economy's booming unemployment's at record lows consumer confidence. Confidence is at record highs in. Almost nobody has a plan for the next recession. And I want you to be honest with yourself. Are you prepared for the next recession and when I say recession. I don't just mean economic recessions if you lose your job or your biggest customer your in a recession if your five best last employees leave and form a competitor your in a recession if your partner embezzles from you you. My friend are in a recession. But don't worry no matter why you're in a downturn it's possible for you to rock the recession and that's what we're talking about today so. Let me get specific. Let me tell you exactly how how to get ready for a recession. If you have a pen pick it up now and get ready to write this down. Step one are you ready the first first step in building. Your recession plan is to do a credit check on your mother-in-law all right I'll series says the first step in building recession session plan is to assess where you and your company are so pollen. I developed the recession gearbox model to help business leaders and you see the four four gears. The Paul used to accomplish his American Dream Exit from his company. First Year is to assess your situation sucking dearest attuned up your business and personal personal life to prepare for a recession third gears to race which means getting your company culture healthy measuring productivity of your employees rooting out profit said Fade fourth dearest. Hit The gas accelerate. This is where you're going to start to capitalize on all the opportunities. The recession brings in. Finally there's the emergency emergency break. which is there in case all else fails? You'll have a backup plan to prevent catastrophe. Now I WANNA take a second pass through this model highlighting tactics that you'll employ in each gear so for first gear. You're going to assess you always start here. You need to know how the economy works at a basic level and you need to understand the economic cycle because it always includes a recession. It's like the seasons of the year spring summer fall winter. Sometimes when arrives late but it always arise in terms of the economic cycle. Winter is always coming in first gear. You assess where we are in the economic cycle. This is also the gear that you're in when he used the recession readiness assessment to understand. How prepared your company and you are for the next down term in the scary your benchmarking your preparedness hardness from there? It's all about evaluating what you learn understanding how much opportunity you have to use the next recession as leverage for massive growth and gathering gathering the documents. You need the shift into second gear. If you want to follow up on first year you can go to recession dot com slash ready. That's our website and you can take the free recession readiness assessment. There takes about five to ten minutes once you're done with first year assessing now you're gonNA tune this is the gear where you perform stress tests to figure out where your personal and business finances are strong where they're weak. You tighten up your business and personal smell affairs in an unemotional way. And then you'll emerge confident for the next year you'll have conversations with your banker to figure out your line of credit. You want to increase your line of credit now before were in a recession before you need it because banks liked to loan money when times are good They don't like to loan money when times are bad. Perhaps my favourite tip of the entire lesson. We're doing today. Is that now to day. Day is the perfect time to ask your banker to reduce lower or cap. Your personal guarantees if you have them on corporate or personal data at Your Bank. They they aren't going to do this. One Time Sir are bad when we're already in a recession. They're going to let you reduce cap. Your Personal Lou Gehrig's disease now when times are good and sometimes you may have to switch banks to accomplish the skull but I think the effort of finding a new Bank of switching banks is certainly worthwhile and it doesn't cost you anything for you to simply ask your bank or for you to shop. Your Bank With with other institutions banks are so hungry for new business right now that it's entirely possible for you to reduce or CAP. Your personal guarantees but times are so. Oh good that most people just don't think to ask so. Please take me up on this huge opportunity. If you have a loan with personal guarantees okay. Once it's worth through second gear now we're GONNA shift in third year race. This is the gear where you're going to be Improving your business improving your company's culture measuring during employee performance measuring Labor
Speed vs. Safety: Rapid Approvals from the FDA
"Why is the FDA's rigorous testing so necessary. Well I I think you're aware that a lot of drugs fail From safety concerns we all know about getting sleepy with antihistamines. Or you know that's the actual aside side effect that comes from the action of the drug on the brain. That's at the senior centers that we would like to counteract allergy. So that's what we call pharmacologic based aced toxicity. It's an effect actually on the target. But it's in a way that we don't want it to act GOTCHA. So as we're working on very new drugs we often don't understand like where there's receptors are in God or the brain or the immune system. There's a lot of things we don't understand about the basic mechanisms of action of disease and there's lot of things that we don't understand sometimes about where the receptors are in the buddy. I mean it seems great. Yeah but that's why. I'm kind of glad if my original training and classic Comic Anthology Because you have to ask questions okay. where else is the receptor? Who else could hit end so? FDA trained to think about those nightmare scenarios of what it could do that. You don't want it to do right and ask those hard questions to make sure that we have the checks and balances right a lot of the early drugs That were used in AIDS. Patients Cause Peripheral neuropathy and that wasn't shown very well in the animal models models but it caused intense pain in the patients at the same doses that was needed for the virus. It wasn't until later that we got the protease inhibitors that really counteracted the road. And that's the basis of the lifesaving therapies that we have today I was really fortunate to be. FDA during that time when the protease inhibitor came through so switching gears a little bit what is personalized medicine. When it comes to patients like for example adjacent armstead and meal Amac? I understand that Jaycee is a twenty five year old with Lou GEHRIG's disease while meal is a young girl with batons disease who have both recently benefited from personalized medicine. He I think we have come to the place in drug development where we understand a lot more about genetics of disease so so yes switching away from viruses and into genetic Madison we have a lot of inborn errors when we learned that there is an inborn Gene that was missing in a patient has always been there born like that and as soon as we can diagnose them and with that replacement gene product or the enzyme of interest interest. We can save their lives so. LS has also been learned to be a whole series of different mutations responsible for LS Um and so you have to look at those different subsets according to their genetic diagnosis. But we also know that Batten's disease is a specific mutation and there's also something like fourteen different forms of Batten's disease that are mutations in same pathway that result in the same type of phenotype of neurological article degeneration some earlier some younger and some an older kids or adults in the case of Mula. She has two mutations that are different on both of the wheels that caused the dysfunction of a particular protein. Batten's disease six seven and there's only a handful or double handful of kids worldwide. They're known to have that particular subtitled batons and Jaycees case she has a very aggressive form of al it lasts called F s mutation and it has a particularly bad course people with F.. US typically sadly succumbed LS typically approximately a year. Because it's so aggressive. It's very hard to intervene soon enough. And there has never been a medication that could actually address the fundamental gene problems in these two cases so we need to design whole new the truck when we find the particular mutation and it turns out depending on the molecular biology and that control mechanisms around them. A tation some all of them are amenable to go nuclear type therapy and both of these girls have been their particular. Genetics have been amenable to A strategy she of using nuclear tight enter equally sadly we did not know that. JC had this particularly bad ale ass us until she was twenty five. Her family had lost her twin sister at the age of seventeen and Alex add add. Actually he contracted the symptoms of L. S. at age eleven so the two girls were identical. They had the same mutation but one got symptoms at eleven on the other at twenty five. JC I guess Through some grace right. Her symptoms arose during time in which a drug was already available in unaccompanied show that happened to be appropriate for her. So I understand and that in this case she got lucky. Well in a way because the drug already existed otherwise we couldn't have intervened quickly enough. Yeah it was an act of considerable effort on the part of the patient advocacy group project. LS The head of Columbia University's LS LS center. Dr Neil Snider in the company who originated the drug and all of us that were helping around the sides trying to support like an exoskeleton including Charles forever and I was helping with the regulatory strategy and also trying to make sure that the drug that was chosen was actually appropriate to the most expedient animal model so as a result of that we were able to put together a very lean and mean I N D for JC and get her approved through the FDA. I have to say. FDA was understandably cautious but when they heard her situation detail and how she'd lost her twin sister the understood of course about a few and they made a lot of exceptions to the usual toxicology regulations. Well I know that she had been she and her family. They had been advocating pretty publicly for a while up until it was approved. I if I'd been in her mom shoes I would have done the same thing called. She lower local congressman. The Stephen King and there was actually quite a response. In Congress. There is a bill that was put forward to ask. FDA to move expediently for JC. I don't know that that had specific impact but just to say that they got some considerable public discussion. And how Camilla's case different in her case Tim you At Boston Children's Hospital recognized that her condition was suitable for an exon skipping being drug very similar to Isis Been Raza and he was able to use a similar backbone and design a drug from scratch within several months it was quite remarkable global. We've done the testing for it and then we've Were able to get started with just a acute data and then I designed a type of a program in which we would update the FDA very regularly on the progress of the toxicology studies so that we could extend her dosing and again. FDA's group group that does an enzyme replacement was wonderful. In working with us to customize that I approach how do you envision cases like these being handled in the future after all not everyone. Everyone has a congressman. That's willing to go to bat for them. Like Jaycee did not. Everybody should take one. There's definitely a sea-change coming is really exciting. And it goes back to the changes brought about by the AIDS patients who identified that they were an extreme unmet medical. Need we see the finalization of the L. S. guidance. We see a lot of guidances have come out on rare disease from the agency in the past twenty four months. And I'm very excited about this because we're really getting to the place where we custom tailor the amount of upfront non clinical research. That has to proceed to human trials customize. That the patient's situation well do you think that each was going to require its own uniquely designed non clinical research at will or will there kind of. Okay you're not gonna be able to have like a standard version that works for most Aso's typically called platform toxicology in kind of a dream. Right now when you look across all a good nuclear tides you find out remember. I mentioned early in this talk about the pharmacologically driven toxicity. Let's say there's another place in the genome that has has a similar sequence. We end up having the drug acting by its intended action bit at the wrong place which is an off what we call an on target but unwanted toxicity existed that could arise by modulating genome which is a little scary right to put something into the spine or once. You invoke gene therapy. What's done is done so you need to have really careful toxicology evaluations that look at the animal as if it were a miniature clinical trial? And you know you're basically siklie handling the animals has patients and so we get as much information as we can vary from each particular experiment and try to make sure that Ed's translation Lee accurate for predicting patient risk. We need the parents to know that right. If if you were me. Resigning are up to our child. An an in-and-out shoes
Walk to defeat ALS
"It and on the ground and it's what we signed when our soldiers are deployed to protect our freedom abroad but now the bravest men and women among us our approach on the ground military veterans are twice as likely to fall victim to a LS the fatal neuro degenerative disease that robs them of the power to use their lax hold someone close a solid meal simply say I love you before ultimately losing the ability to bring most often remain aware and alert to the world around them as their bodies gradually shut you don't need to know about red with a alas to no it must be stopped the those affected your support join the A. L. S. associations wall to defeat a LS to help us find treatments and a cure for Lou Gehrig's disease but the walk you you want to defeat a LS dot