35 Burst results for "Lou Gehrig"
Pat Quinn, co-founder of viral Ice Bucket Challenge, dies from ALS at age 37
"The A L S Ice Bucket Challenge. Has died. Pat Quinn died at the age of 37 yesterday after seven years with the disease. Quinn and the late Pete Frates started the challenge after being diagnosed with a L S, which is known as Lou Gehrig's disease. The ice bucket challenge raised over $250 million Since it took social media by storm in 2014. Those of you do not know
Pat Quinn, Ice Bucket Challenge co-founder, has died at age 37
"J. Powers, Fox News Another co founder of the Ice Bucket Challenge, has died. Pat Quinn, motivational speaker and co founder of the Ice Bucket Video Challenge for a less died Sunday morning at age 37. He battled Amy a traffic lateral sclerosis, often called Lou Gehrig's disease since diagnosis in 2013 the video challenge taking social media by storm in summer, 2014. Quinn talking to Fox News radio in 2015 disease that has no hope at the moment, but The ice bucket challenge is revamped that outlook the challenge so far raising more than $250 million worldwide. Currently, there is no cure for a less a fatal progressive nervous system disease, which impacts nerve cells in the brain and spinal cord, causing loss of muscle control.
Pat Quinn, Ice Bucket Challenge co-founder, has died at age 37
"And another co founder of the Ice Bucket Challenge has died. Pat Quinn, motivational speaker and co founder of the Ice Bucket Video Challenge for a less died Sunday morning at age 37 He better of India Tropic lateral sclerosis, often called Lou Gehrig's disease since diagnosis in 2013 the video challenge taking social media by storm in summer, 2014. Quinn talking to Fox News radio in 20. 15 disease that has no hope at the moment. But the Ice bucket challenge revamped that outlook, the challenge so far raising more than $250 million worldwide. Currently, there is no cure for a less a fatal progressive nervous system disease, which impacts nerve cells in the brain and spinal cord, causing loss of muscle control boxes.
Pat Quinn, Ice Bucket Challenge co-founder, has died at age 37
"Co founder of the ice bucket Challenge for a less died this morning at age 37 he better Amy O Tropic lateral sclerosis, often called Lou Gehrig's disease since diagnosis in 2013, the ice bucket video challenge taking social media by storm in summer. 2014. Quinn, talking with Fox News radio in 2015 is great for the A L s community. We really needed a new sense of fight new sense of hope. So far, the challenge raising more than $250 million Worldwide.
Co-founder of viral ALS Ice Bucket Challenge dies at 37
"The Ice Bucket Challenge for a lesson. This morning at age 37. He battled Amy Oh traffic lateral sclerosis, often called Lou Gehrig's disease since diagnosis in 2013, the ice bucket video challenge taking social media by storm in summer. 2014. Quinn, talking with Fox News radio in 2015 is great for the A list community we really needed. A new sense of fight new sense of hope. So far, the challenge raising more than $250 million Worldwide. America's listening to
Patients increasingly checking ‘Dr. Google’
"As the pandemic continues it seems even more of us are tempted to check our various medical symptoms on the internet Dr Jason west is on the KRLD news line Dr west I recently heard somebody use the term Dr Google and I thought it was a joke but it turns out Dr Google is a real thing it actually is a real the it's what happens when people have some concern symptoms condition diseases I go to the internet and they go to global they type in you know muscle twitches hi twitches restless leg syndrome and they usually get some horrible diagnosis like you know Lou Gehrig's disease or something like that and they'll come into the office and say Dr west I'm dying because Google told me that muscle twitches they have this condition is it a bad thing to go looking to check symptoms on the internet Dr where should we ever do that well I I actually think it's a good bad thing and what I mean by that is I think people get better healing results and stuff when they are informed when they know what's going on but that is a double edged sword because when you start looking for things on the internet you can find you know good and bad just about everything in it does seem to feed on people's fears and the walk in and say look I have this really unusual disease I've got thirty days or less to live in a household where did you get that information in and so it's a double edged sword I mean I mean I really cautious until people to go one way or the other because I think there's benefit in knowing what's going on but it is easily to get swayed into thinking that something is absolutely horrible I am seeing this term cyber contrary us a lot more lately during this pandemic is it something that's grown more rampant thanks to cope with nineteen well I think so because people have more time on their hands there it's unusual off on what's happening and so they're looking for a void to fill so they get on the internet and I started just looking and searching for just about everything and it literally when when you have any health care concern and you start typing in the symptoms the problem is is the likelihood of having a serious disease R. I mean statistically aren't that high but if you type in dry fever cough you know you're gonna come up I've got a corona virus because those are the symptoms but there's a lot of things because the try fever and a cough and a set rule number one if you're going to go see doctor Google on the internet and check a symptom don't freak out it what you find I think it's a really good just reassurance to tell people look there are so many things that can cause a fever muscle twitches of stomachache headache I mean headaches another example almost everybody at sometime in their life will get a headache but as you go type it in the first thing I'll tell you what you could have a brain tumor you could have a budgetary teamwork and then the likelihood of that happening is so low it's almost like winning the lottery I mean in a reverse way and so if people are armed with some reassuring facts like he looked at the statistics of what those serious conditions are let's just see get your physiology balance let me search there with you it really helps so that people don't get into a state of cyber Congress
Mind Over Body Cure
"Well, we've heard quite a few people on this show and others claim that they have thought themselves well, even in the face of death, but what about those people who do get sick and do get worse and die. Are they being made to feel guilty for not thinking themselves well well. My guest today are on opposite sides of this mind over body debate. Doctors don't know why my first guest is alive Lynyrd, borden says He. He changed his attitude. Imagine summarize warriors fighting the cancer in his body. A month later, the cancer was gone my next. Gus was told she had eighteen months to live if she did not have chemotherapy for her breast cancer Jane, Griffiths says she refused the treatment ten years later. She is still alive. My next guest wrote one of the most popular mind over body bestsellers. Dr Bernie seagulls love. Medicine and miracles explains his experiences with. With what he calls exceptional patients who hill themselves in the face of death. My next guest is a doctor who totally disagrees with Dr Segel's philosophy Dr Shirley new says sick. People are being made to feel guilty if they don't heal themselves, and there is no proof whatsoever that any of this works Dr Newlyn is author of doctors the biography of medicine. My next guest got so tired of people telling him that his severe backache. Backache was his own doing because of a bad attitude and stress. He wrote a column in Newsweek. Magazine to complain about it. Meet Rabbi Benjamin Black and my last guest says when she was diagnosed with Lou Gehrig's disease, people wanted her to try acupuncture and Yoga and love to get well and Spain says she live as long as she can, but she is also planning her death. Welcome all of our guests to the show. Start with you. I'll start with you. Because is where we got the idea to do the show from that column that you wrote in Newsweek magazine. What happened? I suffered from a herniated disk and I was just looking for some sympathy. And, then I suddenly realized that there was a psychological change in our society. and. Everybody kept saying to me. Why are you doing this to yourself? You must be the victim of self induced stress. And what really got me upset was that I recall the friend of mine who had died of cancer. who was able to deal with the reality of sickness? But couldn't cope with the fact that throughout the last days people made him feel as if he was the guilty one because he didn't obviously want to get well strongly enough because he wasn't trying hard enough, and he would cry to me. Does this mean I'm failure? What I'm saying is that there's an extreme position today I grant of course that there's a great deal to mind body relationship I grant as well that there is such a thing as love, medicine and miracles. What I think is wrong is I believe is a rabbi that we pray for miracles, but we don't expect miracles and when they don't happen, say that anybody who isn't well must be guilty himself. Don't blame the victim. Victim. Do you think Dr Newland this is making? People feel guilty as they die well. There's no question about that. That's really not my problem with Bernie's propositions. My problem with Bernie's propositions has to do with the aura science that he puts around them, in spite of the fact that what he's actually done is to take an enormous leap of faith, which of course is the secret of it all an enormous leap of faith from certain experiments, which show something that we all agree on that. There is a psychological factor that involves the immune system I don't think any sensitive physician physician with any experience could possibly disagree with the concept that patient state of mind is very important in their illness. But along comes Bernie, and says poof. The mind controls the immune system direct quote, the only quote I memorized from the book burning so that I could use it today. There's no evidence of that, and as long as people continue to believe with their minds, they can control their immune system there believing something that they simply can't do. It's like getting high LSD and trying to jump off a roof and fly, but you yourself just said that it's an enormous leap of faith and suppose it does suppose it does control the immune system, but there is no proof that it does. It's not a question of there being no proof that it does or does not. It's a question of our already being so close to understanding the various factors that do control the immune system that we know that the mind, the conscious mind is only one small factor. What actually happens is that whether we develop immunity to something whether we can control the disease process has to do with three systems in our body.
"lou gehrig" Discussed on Medical Mysteries
"lou gehrig" Discussed on Medical Mysteries
"Stephen Hawking was only twenty one when he learned he had a neurological condition at that point. His doctors weren't entirely sure what it was. Neurological condition is a broad umbrella term that refers to any number of diseases or disorders that affect the nervous system. Some are the result of a specific injury or trauma like when a person damages their spine in a car accident. Others appear at birth or heavy specific. 'cause like a stroke but some of the most baffling neurological conditions are degenerative. They can appear in an otherwise healthy person in slowly. Kill Them. Stephen hadn't had a stroke and he hadn't been in any accidents and since his symptoms were worsening with time. His doctors concluded that he had a degenerative neurological disorder. The next step was to figure out which one while they waited on their test results. The physicians gave Stephen Vitamins that might help alleviate some symptoms in sent him home. Even though Stephen didn't know exactly what was wrong. He knew that degenerative neurological conditions were bad. News many were untreatable and most were fatal to the brilliant student. His nebulous diagnosis felt like a death sentence. He didn't know what to do with the remainder of his life. He'd been a brilliant post graduate student at the University of Cambridge. But he always found school a little boring. It wasn't stimulating enough now. There was almost no point in finishing. Why waste the few years? He had left pursuing a degree. He didn't care about some noted that he began drinking more than normal and the ones out going. Stephen became reclusive. His thoughts were marred by darkness and sleep didn't bring any relief. He often dreamed of a looming execution and would wake up with a start. His life was quickly drawing toward an end and there was nothing he could do to escape those thoughts but slowly over time. Stephen learned to see the silver lining during one of his tests. He noticed a little boy laying in the bed across from him. He'd been maybe ten years old and he was in the hospital to treat his leukemia. It was clearly painful. The boy moaned and gritted his teeth while doctors tried to help in contrast. Stephen wasn't suffering at all sure. He was clumsy and falling down a lot but that didn't stop him from living his life on top of that he was as mentally sharp as ever whatever his condition was. It hadn't affected his ability to think or reason. And who knew maybe his diagnosis would be mild to. Unfortunately that wasn't the case in nineteen sixty three Stevens. Doctors called him with the bad news. The condition was a mile trophic lateral sclerosis or LS. He had three years to live if he was lucky. Stevens doctors didn't know how Alice was caused and they didn't have any treatments or cures but they did understand a bit about how ailes worked so stephen had pessimistic roadmap to predict the course his life would take his neurons were deteriorating at a rapid pace as they broke down signals from the brain had trouble making it out to the body. He'd slowly lose control over his muscles. I it would be minor clumsiness. But eventually he'd be unable to do simple things like pick up a pencil from there. The muscles used to perform basic life functions. Such as breathing would deteriorate and he would die. It was a dark future but Stephen decided to make the most of the time he had and that meant finishing school a couple of years after his diagnosis he applied for a research position at Cambridge. But he could barely fill out the application on his own. He couldn't type correctly. His fingers shook and he lacked the strength to push down on the keys. He needed help so he dictated much of his application to his then girlfriend Jane. Luckily his credentials were strong. Even as his body failed him his mind was as sharp as ever. In fact. Stephen had developed a reputation. His professors claimed he was one of the most gifted students that they'd ever seen Stephen continued studying at Cambridge and passed his classes with flying colors. Unfortunately Stephen could never be recognized for his academic performance alone he was always the boy with a LS. The boy who only had a few years to live except the years went by and Steven didn't die. The disease was still progressing. But not at the speed. He anticipated this allowed hogging to live an incredibly full live that we could spend two whole episodes on but today we're going to be covering the landmarks in his battle with. Ls In one thousand nine hundred seventy twenty-eight-year-old Stephen had been living with a ls. For seven years. He'd been using crutches to get around but the previous year. He transitioned to using a wheelchair. Full-time oddly Stephen maintained a positive attitude about his loss of mobility. He wasn't even supposed to be alive so using a wheelchair didn't seem too bad and just as he promised himself Stephen made the most of the time he had he was married and now had a three year old son and an infant professionally. He was making a name for himself by the nineteen eighties. Steven was the leading mind in astrophysics. He found a way to reconcile two vastly different fields. Quantum theory and Einsteinian relativity he discovered a theoretical new form of cosmic energy produced by black holes called Hawking radiation. He even developed a mathematical model to describe the Big Bang. All those findings are a bit complicated to explain even to other physicists but Stephen was uniquely brilliant the media dubbed him the smartest man on earth but there were few mysteries. He couldn't solve like how he'd managed to survive with AIL S. For twenty years now it was incredible that he was still alive but Stevens still had his struggles in day to day life. His muscles and lungs were weak and sometimes he couldn't catch his breath. He got pulmonary infections frequently in one thousand nine hundred eighty five while at an academic conference in Europe the forty three year old Stephen developed ammonia. The infection progressed rapidly and within hours he had to be hospitalized. The doctors performed a tracheotomy. They made an incision in Stevens neck and inserted a small tube to open his airway. Well the procedures save Steven's life. It destroyed the ability of his vocal cords to work properly. He fully lost his ability to speak. Luckily technology marched on and Stephen found a new way to communicate in Nineteen eighty-six a special computer mounted on his wheelchair. It could vocalized selected words and phrases since he wasn't strong enough to use a traditional keyboard. His device could respond to the touch of a single finger. At first Steven might have found it disheartening. He couldn't even tell us why if that he loved her on own but with time his robotic voice became one of his signature traits along with the speaking. Computer Hawking also used a mechanical wheelchair since he wasn't strong enough to push himself. He gained a reputation among his friends and co-workers for while driving. Steven didn't want to be seen as a stuffy. Old Man with limited mobility like a reckless driver on a freeway. Stephen regularly dodged and wove around pedestrians. His public persona was a little more formal. He didn't raise his wheelchair door. News interviews but Stephen was very direct and sometimes came across as rude even though he needed a computer to talk. Stevens still had a quick wit in two thousand. Eight sixty-six-year-old Hawking's fingers grew too weak to operate his text to speech computer so his graduate assistant came up with a new way for him to communicate. He attached an infrared laser to his glasses. The laser intern tracked small movements on Stevens Cheek. Basically Stephen could flex and move his cheek the laser with track those motions and move cursor on his computer screen. Accordingly Stephen could directed up down left or right spelling out words and phrases for the computer to read aloud. Luckily Stephen had enough money and influence to always get the most cutting edge technology but the wheelchairs and computers only helped manage his symptoms. He couldn't stop the disease from progressing and finally in two thousand eighteen. It took its toll seventy six year old. Stephen Hawking died of complications from the illness he lived with a LS for fifty five years fifty two years longer than his original prognosis. And even as the world mourned Stevens. Doctors were faced with a mystery. Nobody knew exactly how he'd survived so long he hadn't received any different treatments from any other. Ales patient but somehow he lived with the disease for decades and if researchers could figure out how maybe they'd be able to develop a cure.
"lou gehrig" Discussed on Medical Mysteries
"In the Nineteen Twenties and thirties. Lou GEHRIG was the first Baseman for the New York Yankees and a member of what many fans called murderers row because of their ability to crush the ball. He and his teammates were known for their offensive prowess at the plate and for winning numerous world series titles. Gary was a fan favorite but during the team's spring training and Florida in one thousand nine hundred eighty nine. He could tell something was wrong. Power that he'd been so famous for old but disappeared. He was often tired but had no idea why he desperately wanted to play every game and maintain his legendary starting streak but he also didn't want to embarrass himself by getting easily winded or making a mistake on the field even with the disappointing spring training showing he was given a starting spot once the regular season began after all. Gehrig was a in his manager. Hope that he would turn it around in March. Old reliable number four took his place at first base. Gehrig hope that he was passed whatever he'd experienced in the spring instead he got worse all through the month. His dominance at the plate was gone for good and people were noticing the notoriously harsh New York City press question GEHRIG's abilities. They noted that his hand eye coordination was still on point but garrick was struggling with power. He was hitting the ball but it wasn't going anywhere. His teammates noticed how he was struggling to. He was making rare errors at first and was incredibly slow on routine defensive plays on April Thirtieth Nineteen thirty nine. Gehrig went over for four. The played against the Washington senators. A hitless game had been unthinkable the season before but it was becoming his new normal. He couldn't stand to let the fancy him fade away. He knew he had to make a life. Changing decision on May Second. Dariga arrived at the stadium in suited up for the game. He laced up his cleats. And BUTTONED HIS JERSEY. He left the locker room and headed up the steps to the dugout there. He approached the Yankees Manager. Joe McCarthy and said that he was benching himself his starting streak was over at two thousand one hundred and thirty games but benching himself wasn't enough his wife. Eleanor noticed that something was very wrong with her husband at home and grew worried. Gehrig told her that he could feel weakness in his arms and every so often he had a tremor as he worsened she called the world renowned. Mayo Clinic in Minnesota. She told them of her husband's ailment and a few of his symptoms. The physicians agreed to run a few tests. Gehrig was a huge star and they were happy to help him out on June thirteenth. The GEHRIG's flew to Minnesota. He and his wife were hopeful that they'd finally get a handle on. Whatever was going on at the Mayo Clinic. Garrick met with Dr Paul. O'leary he recounted the onset of his illness and his current symptoms. Sadly A- Larry and other physicians at the clinic knew exactly what he was describing. And it didn't sound good everything lined up with. What Sharko had documented over seventy years before the problem was there were many other neurological diseases that fit gehrig's description to and there was no test for LS that meant. The doctors had to rule out other conditions. I guarantee spent nearly a week in Minnesota undergoing medical tests his physicians determined. It wasn't Parkinson's disease or Huntington's disease crossing off more possibilities every day. The list of what it could be was narrowing down to the worst possible outcome. It only took a week to get through all of the tests on June nineteenth nineteen thirty nine GHERIG's thirty sixth birthday. The doctors inform the famous ballplayer of his diagnosis garrick. Sad is he learned the grim news he had. Ls while this disease was rare. It affected over thirty thousand Americans a year and there was no cure. Garrick would just have to let it run. Its Course Dr O'Leary whom Garrick would go on to form a relationship with said that in many cases patients only made it three years before they died from the illness garrick was at a loss for words. He always been a hard worker and he was used to his efforts paying off. He didn't like that there was nothing he could do. Now then O'Leary gave him even more bad news. He had to stop playing baseball altogether. While the activity wouldn't aggravate the condition GEHRIG was putting himself at risk. Every time he set foot on the field his reaction times would only get slower and a one hundred mile per hour line. Drive at first base could do serious damage. Garrod left the Mayo Clinic in quiet despair but he trusted O'Leary's prognosis and knew there was no point fighting it. All he could do was make the best of his final years and say goodbye to the sport he loved on June twenty-first the Yankees announced gehrig's diagnosis and retirement to the public fans and sports lovers. All over. The country were shocked and saddened. Garrick was a hero. Things like this weren't supposed to happen to men with nicknames like Ironhorse to soften the blow the team announced that they beholding and appreciation day for Lou Gehrig on July fourth. Nineteen thirty nine fans filled Yankee stadium to give Gehrig a proper sendoff. Some of his old teammates like Babe. Ruth were in attendance before the game started. Gehrig walked to a microphone in the middle of the field to give a farewell speech. He said fans for the last two weeks. You've been reading about a bad break got yet today. I consider myself the luckiest man on the face of the earth. There was hardly a dry eye in the house as Gehrig left the field for the last time he was optimistic even though his prognosis was in bright he was going to make the best of the time he had but he didn't have long at all. It was only two years later on June second. Nineteen forty one. That Lou Garrick died in his home in New York. It was a sad day for sports. Fans all over the country but the famous ballplayers fate wouldn't be in vain. Gehrig's death brought a pronounced awareness to a LS. He inspired countless donors and activists more money than ever before was funneled into charities and research across the Globe. Now better funded and supported. Physicians threw themselves into their studies. The race was on every day. More people were diagnosed with LS. The scientists had to find a cure and fast Lou. Gehrig wouldn't be the only famous name to suffer the disease before long a ls victims range from Johnstone. The creator of Sesame Street to physicist Stephen Hawking as well as countless ordinary people MOMS DADS SIBLINGS. New Research was their only hope for survival. But perhaps the answer lay in simple bucket of ice..
"lou gehrig" Discussed on Medical Mysteries
"To breathe her muscles in her chest barely had any strength to rise up and allow more Aaron. Each breath came in shallow and raspy. Her time was drawing to a close and she knew it slowly over a couple of days. She succumbed to her illness and passed away. Her death was heartbreaking but charcoal was used to these sorts of tragedies almost all of his patients died but he did his best to bring meaning out of their loss that meant learning everything he could even after death marines body was brought into an operating theatre where Chicago ended. Assistant performed an autopsy. They made an incision along her sternum and cracked open her chest cavity to get a look at our vital. Marie was thin from malnutrition but her heart and other vital organs appeared to be in fine shape with all of these preliminary observations made. Sharko moved onto what really interested him. Her spinal column in eighteen sixty five. There was a huge debate about how the nervous system worked. No one doubted that. The spinal cord was important to movement. But they still weren't exactly sure how everything worked together. Sharko meant to change that. Maurice Body was repositioned so he could get a better look at her spine. Her bone structure looked fine but he wanted to get a look at what was inside her spinal cord. He carefully cut into the spinal column which is composed of thirty three vertebrae. The Vertebrae are protective coating for the spinal cord. A bundle of nervous tissue that runs the entire length of the backbone. Sharko cautiously saw through bone. Each pass had to be shallow and sure if he cut too deep. He risked destroying valuable sections of the spinal cord after what felt like ours. Sharko managed to cut away the spinal column. He finally had the chance to examine the exposed. Neural tissue and there. He was astonished to Find Grace. Streaking lesions lesions are any kind of cut break or abnormal tissue. And they're not always a sign of illness for example. The Mayo Clinic notes. That scars and birthmarks are both kinds of lesions except healthy. People usually don't have any markings or visible damage to their spinal. Cords Sharko was certain that these lesions had caused Marie symptoms. This discovery was revolutionary. He sketched the abnormalities and described them at length in his records. He noted that they were clustered on the lateral column in simple terms. If you were to look at the spinal column from above you'd see it's shaped like a thick ex. There are two branches in front called the Anterior Horn into in the back. The Posterior Horn on either side of the ax is the lateral calm. Murray's lesions were mostly on the lateral column of the spine. This was difficult to explain Sharko. Couldn't imagine what sort of disease would damage the front of the spine while leaving the middle and back alone. He was an uncharted territory. The field of neurology was still in its infancy and there weren't any firm theories about what lesions on the spinal cord could mean. Sharko assumed the lesions had caused Merisi illness but he knew that one individual symptoms didn't make for a solid theory. He needed to repeat the findings and that meant dissecting another person who died of the same condition for the next four years. Sharko kept seeing patients studying and documenting countless conditions. But all the while he kept an eye open for someone with symptoms that matched. Meri's however the illness was apparently very rare because he struggled to find patients who fit the profile not until eighteen sixty nine. When Sharko had another breakthrough unlike Marie who gradually lost her mobility this patient had presented with paralysis as a child but when Sharko performed his usual he noticed that this person had the same kind of lesions on their spinal cord. The one difference they were on a different part of the spine the anterior horn or the front part of the eggs. Once again Sharko didn't know where the lesions had come from or why they clustered around one spot but every new piece of evidence helped him get closer to an answer from these. Two examinations Sharko developed a hypothesis. He theorized that the nervous system had two basic functions. I the brain sends signals to the spinal cord second. The information traveled from the spinal cord to the rest of the body. At least that was how things worked in a healthy person but if those signals got interrupted say by lesions on the spinal cord then a person wouldn't be able to move correctly the location of the lesions determine the specific nature of the patient's impaired mobility in eighteen seventy four. He published his studies and dubbed the New Disease Amaya Trophic lateral sclerosis or a LS. He was the first doctor to show a detailed blink between these symptoms and underlying physical condition rather than purely a psychological one. Despite his revolutionary findings Sharko was still missing a crucial piece of the puzzle. He didn't know what had caused lesions so the next step was to look at which traits his patients shared to see if he could find common cause both of his patients had been women but Sharko didn't think gender played a role in their illness after all he was working at the women's wing of the hospital so it was possible there were male patients. He just wasn't seeing after further research he also ruled out race as a potential factor. But he still didn't know what did cause L. ASS and without knowing the origin he couldn't come up with a cure instead he had to rely on and error. Sharko was a big proponent of using hypnosis to treat his neurological patients and he was having limited success but only in those that had what we know as psychological conditions sadly since patients with LS lesions on their spinal cord. Hypnotherapy did nothing for their symptoms although Sharko didn't know how to treat them. His discovery of the spinal lesions had been huge at the end of his life in eighteen ninety three. His findings were widely accepted all over the world. Since he'd been so diligent with his notes. Physicians knew the symptoms to look for to diagnose patients with AOL S. Most patients were like Marie. They'd start out feeling fine but then slowly grow weak over time. They lose control over their muscles and deteriorate until they stop breathing other patients lost control over their voluntary motor functions. While they are weaker they'd find themselves shaking or spasm ing some would start laughing or crying unable to stop doctors could diagnose from these symptoms but they still didn't know exactly what the lesions were doing nor could they figure out the significance of their location on the spinal column. Why did they appear in different places and triggers such different symptoms while they looked for solutions? Their patients were dying. Doctors remained powerless to stop the condition on top of that the general public was mostly unaware of the illness. So there was little pressure for more research but that was all about to change in the spring of Nineteen thirty nine. One of the greatest baseball players of all time was diagnosed with a LS and he changed the dialogue around the disease forever. Coming up all star first baseman Lou GEHRIG becomes the first face of LS now back to the story in eighteen. Seventy four forty eight year old. John Martin Sharko. A world renowned doctor published the first ever study on a Maya traffic lateral sclerosis or ls. The condition caused by lesions on the patient's spinal column leads to slow muscular deterioration then ultimately death while Dr Shark who discovered the illness. He was unable to figure out what caused the lesions or to cure them but he laid a groundwork that countless neurologists would follow over fifty years of study. They were frustratingly few breakthroughs and by the early twentieth century. There was still no treatment or cure while the disease was well known within the medical community the vast majority of people had never heard of it. This relative obscurity made it nearly impossible to get proper funding for further research. But that was about to change thanks to a celebrities diagnosis.
"lou gehrig" Discussed on Medical Mysteries
Report: 34 Used Vermont Aid-In-Dying Law Over 2 Years
"People in Vermont are now taking advantage of what is known as Vermont aid in dying law the report just released founder of the thirty four cases twenty four were people suffering from cancer for we're due to Lou Gehrig's disease a LS three would due to degenerative neurological diseases and three would do to other events Vermont law requires the health department to release the report every other year with statistics on how many people took advantage of the law to help end their
A final chilly plunge for man who boosted ALS ice bucket challenge
"Dead supporters of the frailties take one last chilly plunge for the former college baseball player whose battle with Lou Gehrig's disease helped inspire the ALS ice bucket challenge Freddy's family saying the eighth annual plunge repeat at a beach in Gloucester will be
Last Fundraising Plunge for Ice Bucket Challenge Inspiration
"News today marks the end of a frigid and very successful fundraiser heat Freddy's battle with Lou Gehrig's disease helped inspire the ALS ice bucket challenge supporters taking one last chilly plunge for the former college baseball player the phrase family says Saturday's annual plunge for Pete a good harbor beach and Gloucester Massachusetts is the last the former Boston College baseball player lived in Beverly a suburb north of Boston he died December ninth after a seven year battle with a alas or any atrophic lateral sclerosis the ice bucket challenge went viral in twenty fourteen raising more than two hundred million dollars for
Pete Frates, Who Promoted the Ice Bucket Challenge, Dies at 34
"He was the former college baseball star who is credited with raising hundreds of millions of dollars for ALS Freddie's died this week at the age of thirty four British grew up in suburban Boston where he excelled at sports eventually playing so our field for Boston College in playing baseball overseas after returning home he was diagnosed with a LS also known as Lou Gehrig's disease back in twenty twelve when he was just twenty seven two years later Frehley's championed this the ice bucket challenge became a viral sensation with celebrities an entire sports teams taking part two hundred and twenty million dollars it's been
Pete Frates, who inspired the ice bucket challenge, dies at 34
"Borough man who inspired the ice bucket challenge has died his family says Pete Brady's died peacefully in Massachusetts the former college baseball player was diagnosed with Lou Gehrig's disease in twenty twelve the ice bucket challenge got started in twenty fourteen Brady says family got involved the challenger exploded on social media I am doing this in honor of key phrase videos were posted online celebrities took the ice bucket challenge including Donald Trump before he became president it raised about two hundred twenty million dollars worldwide beat a LS in a twenty twelve interview P. Frady said the man upstairs has a plan for me there are people out there that don't have my support system or my advantages and I want
Ice bucket challenge inspiration Pete Frates dies at 34
"His family says Pete Freddie's died peacefully in Massachusetts the former college baseball player was diagnosed with Lou Gehrig's disease in twenty twelve the ice bucket challenge got started in twenty fourteen Brady says family got involved the challenger exploded on social media I am doing this in honor of key phrase videos were posted online celebrities took the ice bucket challenge including Donald Trump before he became president it raised about two hundred twenty million dollars worldwide feed a LS in a twenty twelve interview Pete Frady said the man upstairs has a plan for me there are people out there that don't have my support system or my advantages and I want to help them I'm a Donahue
Pete Frates, Ice Bucket Challenge founder, has died at age 34
"And some sad news the man who popularized the ice bucket challenge is dead Pete Brady's was a former college baseball player who had been diagnosed with a LS in two thousand twelve the ice bucket challenge helped raise more than two hundred million dollars to battle Lou Gehrig's disease Freddy's was just thirty four
Pete Frates, Ice Bucket Challenge founder, has died at age 34
"Maybe this was you or your friends taking the ice bucket challenge one reason for a LS Lou Gehrig's disease took the internet by storm in twenty fourteen one of the inspirations for the challenge former college basketball player Peter freebies has died of the illness at age thirty four that challenge has raised about two hundred twenty million dollars
How to Look Forward to the Next Recession
"Welcome to the NBA show. Your Business gets better with every episode. That's why we deliver daily ten minute business lessons for the real world. I'm your host your coach. Your teacher Turow Mars and home. I'm also the CO founder of the Hundred Dollar Mba. A couple of visits training and community online and each episode is a guest teacher episode. Today's is guest is Jonathan slain. And he'll be teaching you how to look forward to the next recession. Jonathan's lane is the founder of recession DOT COM amazing eurorail author keynote speaker then thought leader when it comes to preparing your business for the recession no fear it just be prepared. It's just a matter of time time for the next recession. Recessions come in different forms as Jonathan will explain but the most important part is being prepared being ready so you can actually grow intercession. Jonathan has a lot to cover in today's lesson. So let's get into it. Let's get down to business. The show comes from Amazon. Logistics Amazon Logistics has a new program for leaders who want to build their own a full time package delivery business. Get access to Amazon's logistics training and technology and start building a team of motive drivers in your community to learn more about becoming an Amazon Amazon delivery service partner go logistics dot Amazon Dot Com ups and downs in Your Business in the economy are inevitable than those who are prepared for those who are able to not only survive but strife we brought on Jonathan slain to show US exactly how he shares his own personal story ory on how to actually thrive in a recession. How to be prepared to make sure you're not caught off guard so I'm gonNA pass it to Jonathon now? The cheese you his guests lesson. But I'll be back with my takeaways and to wrap up today's episode so for now taken away. Jonathan Buckle up. My name is Jonathan Jonathan slain in today. I'll be teaching you how to look forward to the next recession. It's time to rock my story. Is that right before the great recession in in two thousand eight I partnered with my brother in law to start opening up gyms fitness businesses. You know like personal training studios. We open new locations locations and we grew very fast. Our studios achieved new franchise records every year. We have the most personal training sessions ever in the history of the franchise is we had the most locations ever in the history of the franchise. We couldn't miss. We grew and grew and grew that is until we ran into into the great recession. Looking back I'm GONNA let I'm not this audience in on a little secret. Nobody wants to pay for personal training training in a recession and worse I didn't have a plan for what to do when the recession hit so I spent the first couple months of the recession curled up in the fetal position in the corner of my office and the other hand Paul My business partner and Co author who I wrote rock the recession with. He had a plan for the recession and he was looking forward to it. He bought a company and he did very specific things to grow at spectacularly using the downturn is fuel that led to his American Dream Exit poll had picked the HVAC business because he knew that he could leverage HVAC service in a recession. In contrast contrast I was in the personal training business because my brother-in-law happened to be a fitness fanatic and then ended up borrowing a quarter of a million dollars for my mother-in-law our law in order to help us survive the recession and the worst part is I'd ending abroad of the money. All at once I borrowed at twenty thousand dollars at a time. So Oh you do the math. That's twelve phone calls groveling for money. Now I've paid my mother-in-law back since and now on a mission to make sure that nobody has to borrow money from their mother in law in order to survive the next down term. You know right now. The economy's booming unemployment's at record lows consumer confidence. Confidence is at record highs in. Almost nobody has a plan for the next recession. And I want you to be honest with yourself. Are you prepared for the next recession and when I say recession. I don't just mean economic recessions if you lose your job or your biggest customer your in a recession if your five best last employees leave and form a competitor your in a recession if your partner embezzles from you you. My friend are in a recession. But don't worry no matter why you're in a downturn it's possible for you to rock the recession and that's what we're talking about today so. Let me get specific. Let me tell you exactly how how to get ready for a recession. If you have a pen pick it up now and get ready to write this down. Step one are you ready the first first step in building. Your recession plan is to do a credit check on your mother-in-law all right I'll series says the first step in building recession session plan is to assess where you and your company are so pollen. I developed the recession gearbox model to help business leaders and you see the four four gears. The Paul used to accomplish his American Dream Exit from his company. First Year is to assess your situation sucking dearest attuned up your business and personal personal life to prepare for a recession third gears to race which means getting your company culture healthy measuring productivity of your employees rooting out profit said Fade fourth dearest. Hit The gas accelerate. This is where you're going to start to capitalize on all the opportunities. The recession brings in. Finally there's the emergency emergency break. which is there in case all else fails? You'll have a backup plan to prevent catastrophe. Now I WANNA take a second pass through this model highlighting tactics that you'll employ in each gear so for first gear. You're going to assess you always start here. You need to know how the economy works at a basic level and you need to understand the economic cycle because it always includes a recession. It's like the seasons of the year spring summer fall winter. Sometimes when arrives late but it always arise in terms of the economic cycle. Winter is always coming in first gear. You assess where we are in the economic cycle. This is also the gear that you're in when he used the recession readiness assessment to understand. How prepared your company and you are for the next down term in the scary your benchmarking your preparedness hardness from there? It's all about evaluating what you learn understanding how much opportunity you have to use the next recession as leverage for massive growth and gathering gathering the documents. You need the shift into second gear. If you want to follow up on first year you can go to recession dot com slash ready. That's our website and you can take the free recession readiness assessment. There takes about five to ten minutes once you're done with first year assessing now you're gonNA tune this is the gear where you perform stress tests to figure out where your personal and business finances are strong where they're weak. You tighten up your business and personal smell affairs in an unemotional way. And then you'll emerge confident for the next year you'll have conversations with your banker to figure out your line of credit. You want to increase your line of credit now before were in a recession before you need it because banks liked to loan money when times are good They don't like to loan money when times are bad. Perhaps my favourite tip of the entire lesson. We're doing today. Is that now to day. Day is the perfect time to ask your banker to reduce lower or cap. Your personal guarantees if you have them on corporate or personal data at Your Bank. They they aren't going to do this. One Time Sir are bad when we're already in a recession. They're going to let you reduce cap. Your Personal Lou Gehrig's disease now when times are good and sometimes you may have to switch banks to accomplish the skull but I think the effort of finding a new Bank of switching banks is certainly worthwhile and it doesn't cost you anything for you to simply ask your bank or for you to shop. Your Bank With with other institutions banks are so hungry for new business right now that it's entirely possible for you to reduce or CAP. Your personal guarantees but times are so. Oh good that most people just don't think to ask so. Please take me up on this huge opportunity. If you have a loan with personal guarantees okay. Once it's worth through second gear now we're GONNA shift in third year race. This is the gear where you're going to be Improving your business improving your company's culture measuring during employee performance measuring Labor
Speed vs. Safety: Rapid Approvals from the FDA
"Why is the FDA's rigorous testing so necessary. Well I I think you're aware that a lot of drugs fail From safety concerns we all know about getting sleepy with antihistamines. Or you know that's the actual aside side effect that comes from the action of the drug on the brain. That's at the senior centers that we would like to counteract allergy. So that's what we call pharmacologic based aced toxicity. It's an effect actually on the target. But it's in a way that we don't want it to act GOTCHA. So as we're working on very new drugs we often don't understand like where there's receptors are in God or the brain or the immune system. There's a lot of things we don't understand about the basic mechanisms of action of disease and there's lot of things that we don't understand sometimes about where the receptors are in the buddy. I mean it seems great. Yeah but that's why. I'm kind of glad if my original training and classic Comic Anthology Because you have to ask questions okay. where else is the receptor? Who else could hit end so? FDA trained to think about those nightmare scenarios of what it could do that. You don't want it to do right and ask those hard questions to make sure that we have the checks and balances right a lot of the early drugs That were used in AIDS. Patients Cause Peripheral neuropathy and that wasn't shown very well in the animal models models but it caused intense pain in the patients at the same doses that was needed for the virus. It wasn't until later that we got the protease inhibitors that really counteracted the road. And that's the basis of the lifesaving therapies that we have today I was really fortunate to be. FDA during that time when the protease inhibitor came through so switching gears a little bit what is personalized medicine. When it comes to patients like for example adjacent armstead and meal Amac? I understand that Jaycee is a twenty five year old with Lou GEHRIG's disease while meal is a young girl with batons disease who have both recently benefited from personalized medicine. He I think we have come to the place in drug development where we understand a lot more about genetics of disease so so yes switching away from viruses and into genetic Madison we have a lot of inborn errors when we learned that there is an inborn Gene that was missing in a patient has always been there born like that and as soon as we can diagnose them and with that replacement gene product or the enzyme of interest interest. We can save their lives so. LS has also been learned to be a whole series of different mutations responsible for LS Um and so you have to look at those different subsets according to their genetic diagnosis. But we also know that Batten's disease is a specific mutation and there's also something like fourteen different forms of Batten's disease that are mutations in same pathway that result in the same type of phenotype of neurological article degeneration some earlier some younger and some an older kids or adults in the case of Mula. She has two mutations that are different on both of the wheels that caused the dysfunction of a particular protein. Batten's disease six seven and there's only a handful or double handful of kids worldwide. They're known to have that particular subtitled batons and Jaycees case she has a very aggressive form of al it lasts called F s mutation and it has a particularly bad course people with F.. US typically sadly succumbed LS typically approximately a year. Because it's so aggressive. It's very hard to intervene soon enough. And there has never been a medication that could actually address the fundamental gene problems in these two cases so we need to design whole new the truck when we find the particular mutation and it turns out depending on the molecular biology and that control mechanisms around them. A tation some all of them are amenable to go nuclear type therapy and both of these girls have been their particular. Genetics have been amenable to A strategy she of using nuclear tight enter equally sadly we did not know that. JC had this particularly bad ale ass us until she was twenty five. Her family had lost her twin sister at the age of seventeen and Alex add add. Actually he contracted the symptoms of L. S. at age eleven so the two girls were identical. They had the same mutation but one got symptoms at eleven on the other at twenty five. JC I guess Through some grace right. Her symptoms arose during time in which a drug was already available in unaccompanied show that happened to be appropriate for her. So I understand and that in this case she got lucky. Well in a way because the drug already existed otherwise we couldn't have intervened quickly enough. Yeah it was an act of considerable effort on the part of the patient advocacy group project. LS The head of Columbia University's LS LS center. Dr Neil Snider in the company who originated the drug and all of us that were helping around the sides trying to support like an exoskeleton including Charles forever and I was helping with the regulatory strategy and also trying to make sure that the drug that was chosen was actually appropriate to the most expedient animal model so as a result of that we were able to put together a very lean and mean I N D for JC and get her approved through the FDA. I have to say. FDA was understandably cautious but when they heard her situation detail and how she'd lost her twin sister the understood of course about a few and they made a lot of exceptions to the usual toxicology regulations. Well I know that she had been she and her family. They had been advocating pretty publicly for a while up until it was approved. I if I'd been in her mom shoes I would have done the same thing called. She lower local congressman. The Stephen King and there was actually quite a response. In Congress. There is a bill that was put forward to ask. FDA to move expediently for JC. I don't know that that had specific impact but just to say that they got some considerable public discussion. And how Camilla's case different in her case Tim you At Boston Children's Hospital recognized that her condition was suitable for an exon skipping being drug very similar to Isis Been Raza and he was able to use a similar backbone and design a drug from scratch within several months it was quite remarkable global. We've done the testing for it and then we've Were able to get started with just a acute data and then I designed a type of a program in which we would update the FDA very regularly on the progress of the toxicology studies so that we could extend her dosing and again. FDA's group group that does an enzyme replacement was wonderful. In working with us to customize that I approach how do you envision cases like these being handled in the future after all not everyone. Everyone has a congressman. That's willing to go to bat for them. Like Jaycee did not. Everybody should take one. There's definitely a sea-change coming is really exciting. And it goes back to the changes brought about by the AIDS patients who identified that they were an extreme unmet medical. Need we see the finalization of the L. S. guidance. We see a lot of guidances have come out on rare disease from the agency in the past twenty four months. And I'm very excited about this because we're really getting to the place where we custom tailor the amount of upfront non clinical research. That has to proceed to human trials customize. That the patient's situation well do you think that each was going to require its own uniquely designed non clinical research at will or will there kind of. Okay you're not gonna be able to have like a standard version that works for most Aso's typically called platform toxicology in kind of a dream. Right now when you look across all a good nuclear tides you find out remember. I mentioned early in this talk about the pharmacologically driven toxicity. Let's say there's another place in the genome that has has a similar sequence. We end up having the drug acting by its intended action bit at the wrong place which is an off what we call an on target but unwanted toxicity existed that could arise by modulating genome which is a little scary right to put something into the spine or once. You invoke gene therapy. What's done is done so you need to have really careful toxicology evaluations that look at the animal as if it were a miniature clinical trial? And you know you're basically siklie handling the animals has patients and so we get as much information as we can vary from each particular experiment and try to make sure that Ed's translation Lee accurate for predicting patient risk. We need the parents to know that right. If if you were me. Resigning are up to our child. An an in-and-out shoes
Walk to defeat ALS
"It and on the ground and it's what we signed when our soldiers are deployed to protect our freedom abroad but now the bravest men and women among us our approach on the ground military veterans are twice as likely to fall victim to a LS the fatal neuro degenerative disease that robs them of the power to use their lax hold someone close a solid meal simply say I love you before ultimately losing the ability to bring most often remain aware and alert to the world around them as their bodies gradually shut you don't need to know about red with a alas to no it must be stopped the those affected your support join the A. L. S. associations wall to defeat a LS to help us find treatments and a cure for Lou Gehrig's disease but the walk you you want to defeat a LS dot
"lou gehrig" Discussed on KQED Radio
"The Beatles had just made their first appearance on The Ed Sullivan Show February ninth nineteen sixty four they're Sullivan trying to introduce caps and there's a gallery full of kids all screaming for a Beatles encore. very in may nineteen twenty five a New York Yankees baseball player was benched bringing to an end his record breaking streak less than a month later the player who replaced him was himself replaced his replacement immediately began his own streak and eventually broke the same record what is that all about Johnny bench. the the Yankee that that was benched was that was is that Lou Gehrig Lou Gehrig was the one who replaced the one who replaced the one who was benched. so Lou Gehrig replaced Pete rose. it wasn't the Yankee rather than naming random baseball players. I've run out of the ones I know. there was a player who had a streak broke a record than he was benched replaced by somebody else a month later somebody replace that guy and started his own streak and broke that same record and Lou Gehrig is the guy at the end of that chain who would've been Babe Ruth and know what's the record you want to know what the record as well what is the record for most can most consecutive games played and longest says you answer..
"lou gehrig" Discussed on ESPN Chicago 1000 - WMVP
"Numbers and its records, but a rare feat was accomplished Monday in the minors. The Reno aces. Aaa affiliate of the Diamondbacks had center. Fielder Matt Scherzer. I think if the cycle and designated hitter. Yes. Mani Tomas hit four homers. This feat has been achieved once at the big league level in nineteen thirty two when Lou Garrick hit four home runs at teammate, Tony Lasari. Tony lies hit for the cycle for the AKIs. This experience was brought to you by farmer's insurance. They head of the game. Find that agent today at farmers dot com. So you decided to go nickname there on twenty lads instead of the iron horse Lou Gehrig. Yep. Okay. Everyone knows that one. No one knows about Tony Lasse. Tony labs is a good player. I think the allows probably all Famer that. Did you know that I don't know Horton for those nineteen twenty seven to nineteen thirty seven Yankees? I'll check it up. You want those airy numbers. Yes. Sure, finalize happy, thirty ninth birthday to the video game. Pacman happy birthday to. That'll care. Good luck. I can't wait till we get to these Tony last stats. We'll do so in a second all star nineteen thirty three that. But a tweeter writes in has it occurred to you that if I wanted to listen to Stephen a Smith. I would do, so he is a stain on the trousers of mankind. You'll get the show. Confirmed hall of Famer, I mean, Tony Laszlo lives in Cooperstown forever. Tweeter better watch is mouth because not only does he not get the show. He might get these hands. It's, it's interesting that he played back in the thirties, and then get into nineteen Ninety-one. It's quite the weights. There's nothing interest five years to the day about what you're saying. Tony Lazaris actual nickname is push him up twenty I mean, the grades get in five years after every tire Tony lies. Got in fifty five years after he retired that up life retire from life. But he's in. He is in with one hundred seventy eight career homers. All right. What else does this look like listen? That's like five hundred back, then I mean, it is he died at age forty two and just player photo, he looks like he's sixteen people so much older back then. Notice that. Yeah. The mortality rate, people died early back then. Yes. Greg Cody running around. Google the age. And I was like, no, Mickey Mantle is actually twenty three here. What? That was the booze boost for everybody back, then evidently, fifty war. That's good. How did we get here? Why is it that you're talking about Tony last league staff? Reno aces. Got us here. You got his nickname wrong. What is it? Tony. You just call them Tony lands. His friends. Call him again. You had a vailable to you. Lou Gehrig Lou Gehrig, doesn't have multiple nicknames. I'll check it out of the iron horse is the one that many people go by listen, Tony last Garrick Babe Ruth murderers row. Okay. So you go to another nickname Joni last year moving onto the next horse. Biscuit, pants BUSTER, lauriston or Columbia. All right. Hold on a second. Let's examine this. No. It also cites Lewis, one of his nicknames because his name was Henry. Wait a minute. What Lou Garrick wasn't Louis was, but it was Lou Aaron. What I'm sorry, all time home run leader. Are you not understanding what we're doing clearly? What's happening? I'm getting flashbacks of it. I opening segment of tell the people finally tell the Tony lies. Tell the people finally because this is the thing that God's essay here he digs in on the mistakes. And then everyone gives them the applause and keeps making the mistakes. He had no idea what we were doing there. So explain to Mike explained, Mike. The people the nature of your frustration to God's on Saturday, that he kept just going for the applause, trampling your job. We had a will Cain joke set up for the very end of the segment. The first words got says on the sage is will Cain and later gives will Cain a microphone before. We're supposed to give will Cain a microphone. We fed him pretty great jokes. PF commenter, who joined us on the same sort of crashed it, you wouldn't have known that because not only do not know, PF name, which was became obvious. He forgot the line entirely. He almost cursed when I told him. Hey, let's not dilute the f bomb because we have it saved for a special. Moment here. He got the timing all screwed up on the comedic joke that we were going to tell Katie Nolan. He was an absolute disaster in the first segment, and he was just smiling the entire time. Oh, he put his drink right on top of the computer, though. Cantu sounds as well. Everyone's the first four minutes, everyone loved the first four minutes just it's the same thing that Cody does it's like just giving the law. What are you, what are you so worried about Mike? Well, we'll Cain was in general admission and the VIP's were in VIP was going to be a surprise that will came emerged chime in obviously people notice. We'll came was there because when he walked out, he was the loudest booze. I had ever heard in the theater of that is that what that was. I couldn't figure out where all that Boeing was coming from. And why the booing was happening. I was in a different part of the Bill came being escorted to his seat. Minding his own business. Wrestling, and he ain't it up up to me. He loved it. Any turned to was escorting did you get.
"lou gehrig" Discussed on The Dan Le Batard Show with Stugotz
"Pushing Tony? You didn't hear them. You just call them Tony lads. That's what his friends. Call him again. You had available to you. Lou Garrick Lou Gehrig. I doesn't have multiple nicknames. I'll check it out of the iron horse is the one that many people, you know, they go by Tony last Garrick Babe Ruth murderers row. I mean okay. So you go to another nickname, you don't like Joni lands, you're moving onto the next horse biscuit, pants BUSTER, low Rueben or Columbia, aren't hold on a second. Let's examine this hungry Lou. No. It also cites Lewis. One of his nicknames because his name was Henry. All right, wait a minute. What Lou Garrick wasn't Lou was. But in Hebrew is. Lou aaron. What, what I'm sorry. All time home run leader. Not getting those. Are you not understanding what we're doing there? Clearly, what's happening. I'm getting flashbacks of the first opening segment of all right? We'll tell the people finally tell the they were gonna get off Tony lies. Tell the people finally because this is the thing that happened gods. Yes. See here he digs in on the mistakes. And then everyone gives them the applause and keeps making the mistakes. He had no idea what we were doing there. So explain to Mike, the nature explain my to the people. The nature of your frustration was to God's on Saturday that he kept just going for the applause, trampling your job. We had a will Cain joke set up for the very end of the segment. The first words to got says, on the sage is will Cain and later gives will Cain a microphone before. We're supposed to give Wilkie microphone. We fed them pretty great jokes. PF commenter, who joined us on the stage in sort of crashed. It you wouldn't have known that because not only to not know PF tease name, which was became obvious. He forgot the line entirely he almost cursed when I told them. Hey, let's not dilute the f bomb because we have it saved for a special moment here. He got the timing all screwed up on the. Comedic joke that we were to tell Katie Nolan. He was an absolute disaster in the first segment, and he was just smiling the entire time. Oh, he put his drink right on top of the computer. That was to sounds as well. Everyone's on the first four minutes. Everyone loved the first four minutes. It's the same thing that Cody does it's like just giving the law. Over rub it on my nibbles. The what are your what are you so worried about Mike? Well, we'll Cain was in general admission and the VIP's were in VIP was going to be a surprise that will came emerged. Chime in obviously people notice came was there, because when he walked out he was the loudest booze. I had ever heard in theater of that side. Is that what that was? I couldn't figure out where all that booing was coming from. And why the booing was happening. I was in a different part of the Bill, which is will Cain being escorted to his seat. Minding his own business. Wrestling, any needs it up up. We're got to me. He loved it any turn to escorting them to get that for social. Loves that. History of sports media loves everyone's poisonous hatred..
"lou gehrig" Discussed on 94WIP Sports Radio
"If you want to get in now i want to change gears here for a second because i'm a history guy now i love the history of sports in it's just so long and the way the game's change over the years and all the big personalities and one of those big personalities that has had a lasting effect instill if you ask i think if you ask the average american right not even just a sports fan you ask an average person anywhere in the country who lou gehrig is i think the no he's just he's one of those fundamental american names you think of the classic americana it's lou gehrig's those black and white images of the yankees hat and guys like him and babe ruth and joe dimaggio and all that stuff so garrick is a a major part of sports history and today june fifteenth nineteen thirty three eighty five years ago today was actually a really interesting one because here's what happened the day before lou gehrig and his manager joe mccarthy they are expelled from game by the manager to get an argument or by the empire the get an argument they get tossed from the game now there's something peculiar that happens when garriga mccarthy get tossed it's that mccarthy gets a three game suspension and gehrig doesn't get anything nothing rejected same time for the same infraction arguing the same call one suspended three games and the is not and you might be asking yourself well why is that how come lou garrick didn't get suspended well it's because lou gehrig was working on the consecutive game streak he had one thousand two hundred and forty nine games to his name and so by not suspending him and letting him start again on this day june fifteenth nineteen thirty three they allowed that streak to continue and and it went as far as it did and and it's so fascinating because it asked so many questions when you when you hear about that right like he it seems pretty clear you should have gotten suspended and they didn't so they could keep a record streak going and it's not the only time that this happens for garrett by the way there's a lot of times where for example they didn't wanna play them in games it's getting to the the pennant race.
"lou gehrig" Discussed on ESPN Chicago 1000 - WMVP
"Nothing wrong with having back to back seasons with sixty something wins astros did it the cubs did it you do it hopefully win a world series to get the first pick next year get the first pick did you see this is e albee's joined a pretty impressive list of players historically the last one hundred years of baseball okay all the way back to nineteen o eight one hundred ten years yes it is excuse me one the last one hundred and ten years of baseball yorker ozzy albee's became just the twenty third player ever in the last one hundred and ten years to have at least thirty extra base hits in his team's first forty two games number one all time with thirty six extra base hits any guesses number one all time with thirty six is an older player of much older player who is very very famous i'm gonna go with mel on no not melon melon i do think is on this i'm going to go with rogers hornsby lou gehrig the correct answer lou gehrig had here's the list of guys that have had at least thirty extra base hits listen to the company he's with lou gehrig paul waner i don't know where that is kevin mitchell lance berkman.
"lou gehrig" Discussed on Newsmakers
"All too well the socalled lou gehrig's disease and it's been a great outpouring from the baseball community in the time since you know donations made by players to the fight against a ls and of course a scotty spent a few days at home with his family away from the oakland as he came back on tuesday night join them at fenway park and his first bad back here's what happened stephen piscotty back with the ball club the celebration of life or as mother gretchen that took place yesterday in the east bay how about that steven scotty baby is gone the scotty family and pleasant if you're standing in cheering or maybe a little tear we know why he touches his heart said and looked up the skies and congratulations steven fiscal joe homerun number three four scotty the more emphasis than the other one so that doesn't give you goosebumps richard nothing well yeah i think they're just things that have happened that you can't put into words in this whole process of john mosaic trading him to billy being so he could be so stephen could be near as mom and then the standing ovation he got in oakland last weekend when he he came back before taking the bereavement leave you know he was he was standing at home plate crying and then to his first game back they had a home run these are moments that you really can't put into words and it's just it was it's just you can't like you said you watch it you know your touch by.
"lou gehrig" Discussed on WHYR 96.9 FM
"To help stephen hawking experience weightlessness he wanted to fly in space and to really show that he can do this given the incredible challenge that he has with his body with a ls lou gehrig's disease and the essential basic paralysis a the majority of his body but he's wanted to fly ultimately a fly out into space so the first step has for many wannabe astronauts and the actual astronauts is to experience weightlessness in something called the parabolic flight where airplane is flown way up to about thirty thousand feet and then gently arcs over descends down to twenty four thousand feet in about thirty seconds and in that time but people inside experienced says were passing through the gravity field of earth is just as if we were in outer space and so hawking wanted to do that i think both for the ability to demonstrate that people with body challenges like his can do it but i think also fun the guy was just totally excited about so many things you know we heard all these stories in the past week since his passing about heating such a jokester and loved just enjoy things and so wanted to have fun too and that was peter offered to him through zero g and asked me to help out in working with teen to enable hawking to do that so before we go on i must say how incredibly envious i am not only did.
"lou gehrig" Discussed on StarTalk Radio
"Your favorite food favorite trick now at quays you those results peer reviews anything chang cal then it becomes a relation to relationship so just in case anyone who's been living under a rock stephen hawking has what we call lou gehrig's disease l s so and it's gradually paralyzed over the decades and right now he communicates through twitches in his cheek and these are red electrically and he moves the cursor up and down on that screen which we got a brief glimpse up and he basically bangs out the spelling of words and ultimately sentences and then scientific papers that well yes so janet about his favourite equation this is was this incredibly stunning discovery that hawking made the entire of black hole is that nothing can get out of it that's the whole idea can't reflect light it can emit light what falls in never comes out again when you talk about the area of the black hole what you're really describing is the region after which no information can ever escape nothing so this is the surface region surrounding the black hole yes there's nothing there it's not a surface of any material kind it's simply a boundary that separates what can come out and can never come out again and amazingly hawking realized in some sense which seems intuitive in retrospect but it was very difficult that really genius really after somebody tells me can't emit anything it certainly can't you can't even light or be eliminated in any way but what he realized was that if it absorbs stuff it must be taking entropy out of the other side of the boundary right entropy being a measure of disorder or randomness or in some sense energy and so if it takes entropy there is a law genetics that says always increases your room gets messier not cleaner without intervention so disorder always increases and so if it's taking inch out of this side of the boundary it must actually be producing its own entropy and each time it takes something in it gets a little bigger and has a little more entropy so in what form is this entropy is really the mystery then hawking realize the black hole must be evaporating must actually be radiating at a temperature like a hot object.
"lou gehrig" Discussed on 1A
"A exhibition game where the yankees cames chatanooga the play the lookouts uh the coach put his uh his girl pitcher on the mound and she faced babe ruth lou gehrig antoni liz airy um she struck out babe ruth i can't remember if it was swinging are looking a he was furious i guess it must have been looking because he kicked dirt on the umpire and stormed back to the to the dugout and then she face lou gehrig and struck him out and he was more of a gentleman than ruth he tipped his hat to her as he left the batters box and then tony lose area i think she walked and then they took her out of the game and of course the uproar was that it was all a publicity stunt and that roof gehrig had willingly made themselves strikeout victims of the seventeen year old girl um and that's kind of the way it goes as if a girl is really good at baseball either they create a by law to get her off the team or they say was a stunt isn't that exactly what happened with the major leagues big change the policy yeah well i as far as i know there has never been a policy saying the girls can play major league baseball there is a whole history of well yeah i guess the commissioner baseball um ford frick in the early 1950s made it explicit but it wasn't for major league baseball there was a woman who was being very effective playing minorleague baseball and so he actually wrote it into the bylaws a baseball that unna women could play glad to hear some of you sharing your stories about this including men and women sharing stories charles emailed i used to think that women shouldn't and even couldn't play baseball like men that i dated the woman who is now my wife she stumped miette tennis out road me on a bicycle outran me any distance and outs swam me at the pool we then had four daughters who were all far more athletic in meet one of those daughters became a professional athlete i can see no reason at all why women can't compete with.
"lou gehrig" Discussed on KTRH
"Catchers or particularly with an obscure player but he later became a very in doubt the discovery lou gehrig way or hot but in an interview in the fifty if i found out who can't only privy picked out an research he said that pictures earth leaving they caught with how can i for and his and the old way to the fact stop cop hm y and that in this very hiding moment of knock nickel hands in the big ardy live and that you would have gotten a little former faith because of that but if he makes me part of that quotes agree all quickly in a way it was really by four because i wish him the way for often pay for you can look at this picture you can look at this of you the any explanation when you really fit act behind will happen the i can opt to ferry hiding players the ferry fearing player coming them not to pull out of the cap hold argue with him and then you know of course a lot of heightened in the in the standard of the ballpark in in the movie cobb with with tommy lee jones which again sort of perpetrated these of these rumors are allegations that he was a dirty player they also pretrade him as a loner in that that he was sort of reviled by by his own teammates now he was hard on his unease on his fellow teammates the rookies for example and he knew was a real pecking order uh with ty cobb that you didn't you know he didn't crossed that line but was he hated by his own players he had enemies and this is you know again i don't make him into a saint he was either gonna major league twenty three and a half years and and some people is jealousy puerto rico and some porter also the reason was he could.
"lou gehrig" Discussed on The Dan Le Batard Show with Stugotz
"And you get a hold of all the artifacts the lou gehrig's glove babe ruth that uh the ted williams stuck you literally get the hold it in your hands you've got to put this white gloves on uh but that's a very cool this well then so we've got big things uh on the four big board we've got a smart things on the grant thornton many board we just added a really cool royal caribbean cruise uh for seven nights tell me bahama throws in a really nice uh i'll fit through uh to people and a travel pack luggage and then a case of a rum on that trip up brute gall rumself there was that there's something for everybody our joined the marlins foundation for the twelve th annual fox sports florida fantasy auction gets night six thirty beds can be placed in person or over the phone if you want more information visit marlins dot com slash fantasy a argued dallas my idea on your social media days to read more critical tweets i want more critical tweets and the broadcast i think those are funny are they not allowing you to do that no i i'll play it i did you hear last night show that i'll i was here last yet but i felt a couple of nights ago you read something that was pointed and i thought it was funny and i took inventory of it yeah i do that on i would i'll be honest with you the ever it went from email twitter we get lat comprehensive questions or tweet that are i mean a lot of it is just follow urge the statement a non sequitur but i think i read a you guys suck last night um in terms of announcers yes it's more of that rats against you need to encourage more courage more i love the airbridge walled city jet saying and and you know fatty mix fatty rights and you guys suck.
"lou gehrig" Discussed on ESPN Chicago 1000 - WMVP
"Club normally in baseball the finger the number the greater the achievement six hundred home runs is an enormous number one deserving of great celebration but for alber pool halls his other round number homer there's one hundred two hundred three hundred four hundred or more noteworthy an impressive because they came during one of the greatest 10year stretches by any one in majorleague history kubo said his one hundred calmer at age twenty three two hundred twenty five three hundred twenty eight and four hundred at age thirty number robert hall in those first ten years pools finished in the top ten of the devoting every season including three firsts four seconds of third or fourth annan knives it was arguably the best first ten years by any one in history and those year there's elevated pools to buy most insist go measures one of the three greatest i face little of all time joining the greatest lou gehrig and jimmy fox dumb on bread outward walls full holes as the last two hundred home runs have been somewhat of a struggle due to injuries moseley to his legs and see he has become more of a slugger than a great great hitter but now he is joined barry bonds hank aaron babe ruth alex frederick is willie mays ken griffey jr jim tell me and sammy sosa in this six hundred club six have now joined since two thousand only three got there in the first ninety years of modern baseball pool holes could be headed someday i seven hundred own runs by but we will never forget house sensational he was for his first four hundred two major accomplishments from the big leagues while the warriors came up big in game one we'll see if flavor could use the two days off the turned things around free throws were good warriors what are they a second fa dominated ordering a bear finals goes to golden.