35 Burst results for "L. D. L"
Prisma: Modern Database Tooling with Johannes Schickling
"Honest welcome back to the show. It's great to be back under so thanks so much for having me. Of course you run. PRISMA and PRISMA is involved in workflows for accessing data. Can you describe the AP? Is that sit between the front and the back end database layer, and where PRISMA fits in sure so I think that's a pretty complex questions. It's always. Always depends on what your application architecture looks like, and there's so many angles to take does feed for example, take a more mortar jam, stag texture, or if you take a micro services architecture, the onset is always depends. What's always the same as if you build application that requires state of assistance? Then chances are you're using database and how PRISMA fits into. Is that it tries to help application developers built applications more easily was working with the databases so typically that means you're using a part of PRISMA. What's called the prisoner client that sits typically in your application server? That's typically an API server and talks to your database. Typically, this part of the stack is known as an or layer or data access layer. PRESI-, in particular is not an Orem can talk about that separately. The pretty nuanced topic, but prison up to. The main function is to serve to access state. I'm more easily in your application language. Can you talk about that in more detail? Like? Why would I need a additional layer of access I? Mean I think in general? I if I'm sitting on the front end and I want to access the database I m hitting some service that services talking to a database and the service is requesting the data from the database. Why do I need prisma to help out with that database access so this setup just to recap one more time, so you have your fronton application. Let's say you have reactive of you up on the other end. You have database. Let's say you have a more traditional postures, my sequel database, but would also apply to same for more modern. Modern Dynamo DB etc, and then typically have this middle tier that's let's say an API server, and where you would use prisma for is just having an easier time building your API server in order to talk to the database, so let's say you're using pastas. The most barebones thing you could do is implementing your Api Server and just writing implementing your points, or let's say rebuilding a graph gals over implementing overs, and then just talking directly to the database by writing raw sequel. Curry's and that works, but that comes also was some problems. Problems typically in terms of productivity, and does not quite abstraction level that you want as an application developer to be productive and confident in what you're writing the same way as fronton applications are built through abstraction layers. Let's say react angular view. It's the same on the back end that you also want more application at U. Matic obstruction layer for away you talking to the database, and historically there's been many forms of the most common one is in Orem, and they're on more modern ways of how you build a better abstraction on top. Top of fear database for data access, and that's a pattern that implementing was prisma that to be referred to as careerbuilder. Can you explain in more detail? What is the difference between a query builder and an OEM right? So that comes down to the way how you're thinking about these application patterns, an Orem stands for object, relational knepper, and the idea behind an orum is mapping a typically a database table to a class in typically object oriented programming language, and this is a pretty intuitive model and is widely used in tons of. The most prominent one of be being active record as part of friggin rails, but there tons of other ones as well and the Java world. There's hibernate and the idea there you have tons of tables in your database, and you want to map that somehow and Julia programming language and your programming language. You're typically working with classes as opposed to a career rebuilder with looks more like sequel way, but maps you sequel statements into statements in your programme language and the difference really come down to how much flexibility and control you need, but they're tons of downsides of or and that as Good more widely used became more and more well known, so there's a great block posed called the Vietnam of computer science, which is all about or ems and the problems behind orum's most importantly one thing called the object relational impedance mismatch. Talks about the problems of mapping databases database tables to objects where he's just a big amount of oven, impedance mismatch, and the way around that is that you should think about the craziest that you're writing a database instead of obsessing too much about the classes and objects, and your curry should really determine the shape of the data. You're getting back in the same way as the British striking analogy to how gruff LDL's was the sort of pattern where draft, but L. is all about the quarry writing that you need in your components, and it's a pretty similar pattern that you're now applying the way how you do. They access on the back end. If I was to set up PRISMA for Miami application. What would the life of a query look like and the structure of a query look like? So what you'd be using concretely, there is prisoner. Database took. And what you would use to career database is a part of prisma called the PRISMA Klein's. The prisoner client is basically just a Java script library that you installed installed from NPR. And you're. Writing that query ones in your coat. One great advantage is that it's fully type safe by leveraging type script, so you're writing that query and then strode run times when your application is deployed. That code gets invokes that under the hood generates a database dependent query, typically a sequel query, but as we were supporting of databases, swell could generate dynamo queries, Atra, and these queries are centered underlying database, and the data's returned, and then returned injury application code. Got It and. What the difference between using PRISMA AND USING GRAPH KUNAL! So, it's a really two fundamentally different technologies for different use cases I. think a good way to think about is where into application stack. These technology said so graphic. L. is typically used for fronton applications to talk back end up locations whereas prisoners specifically the prison. My client is used for typically your backup location to talk to your database so analogous in this way, but typically the different layers of the stack. However, it always depends was newer approaches like the jam stack your friends and education can statically directly talk to
FDA approves drug that lowers cholesterol in a new way
"The FDA has approved a new type of cholesterol lowering drug aimed at millions of people who can't tolerate or don't get enough help from widely used Staten pills like Lipitor and crestor or next let's call is for people genetically predisposed to have sky high cholesterol in people who have heart disease and need to further lower their bad cholesterol high LDL or bad cholesterol is one of the top risks for heart attacks and other problems studies showed that next to tall could lower LDL by about twenty five percent when taken alone and by an additional eighteen percent when combined with the
FDA Clears New Type of Cholesterol Drug
"Well the FDA has approved a new type of cholesterol lowering drugs aimed at millions of people who don't get enough help from Staten pills like Lipitor and crestor or nextel tell and next to tall is a daily pill and studies show it can lower LDL or bad cholesterol by about twenty five percent when taken alone and by an additional eighteen percent when combined with the
Trendy diets may not be sustainable for long-term cardiovascular health
"This morning he was in the American heart association says eating healthy is good for your heart health but how healthy are those trendy diets you know like the keto when the intermittent fasting which is so popular right now CBS's doctor tearing a ruler tell CBS this morning it depends on what your goals are so a lot of patients a patient of mine ask about the keto diet and it's very popular it's popular primarily for weight loss in it can induce a pretty rapid weight loss over two to six months the issue is is it sustainable and the problem is when you're really limiting yourself to less than fifty grams of carbs which is like one slice of bread or one apple we find that over time it's really not for a lot of people and when you look out one to two years any of facts that a house on either wait for blood pressure blood sugar seem to be similar to other low calorie or low fat diets and the other issues we really don't have a lot of long term research to prove either the safety of the keto diet or any sort of hard but we were just looking at the graphic seems up some downside right so higher cholesterol exactly so because you're eating ninety percent fat a lot of people choose saturated fats so things like coconut oil butter bacon red meat and that can drive up your LDL which is your bad cholesterol yeah in addition you may be depleted of things like magnesium or selenium which is a mineral and that could be pro arisen back in fact there was a study this past fall that show that individuals who ate the keto diet was associated with increased risk of atrial fibrillation which is an irregular heart rhythm right and then because you're not eating a lot of vegetables fruits and lagoons you're really not getting those anti oxidants and the fiber that we know is so would you advise patients then so I do have that sort of wristband of a discussion with them and try to tease out well why are you doing us if it's really just for a short term kickstart weight loss that might be okay but then at that six month mark you probably want to transition to a more healthier pattern of eating is something that's sustainable that's always yeah yeah the internment the internment of intermittent fasting diet I know a lot of people on it swear by it really like it Vladimir do TA yeah yeah my father yes your dad is also a lot of people do it and how does that affect your heart so again the science isn't there a lot of the studies have been in animals and there really haven't been long term studies but what we know is that it does seem to kind of reset the body a little bit when you have that time where you're not eating that fasting period and that can allow the body to kind of clear out toxins it can regulate blood pressure and heart rate and blood sugar and cholesterol in the anti inflammatory there do seem to be the potential for benefits are there no houses we don't really you know again because I'm really study that long term but you're sexually inducing a state of ketosis similar to the keto diet because you're allowing your body to break down fat as you all know I'm certain times there's different types right there's alternate day fasting there's sort of a fasting for time restricted feeding where you eat only for six or eight hours during the day and then you don't eat how is your dad also a cardiologists liking it I I he likes it I couldn't do it is very hard for me to skip breakfast for example noting but a lot of people really do swear by it and talked and really says plant based diet to the ones that are the very best for your overall
Do I Recommend Soy Foods For Boys?
"Was really excited when add instagram. Which is at. Uk is nutrition? If you're not following me there yet you asked me this very question. And that's why I'm about to share this topic with you. You but really interested when I spoke about soya which is a high quality protein meaning it contains all nine essential amino acids and he can link into the previous episodes which talks about what are the best plant based protein to give your child who refuses meet and then of course we'd spoke about soy and he said to me. Is it okay to give soy two boys? So that's what we're going to uncover today. Soy Foods are still feared by parents. Simply because of the uncertainty around how the phytochemicals especially the eyes of Levin's behave insurance bodies. There was a previous lab and animal base studies that sort of fear mongering and hinder the reputation of soy foods. So today we're going to discuss the latest evidence and whether you should avoid or embrace soy foods for a boy but I won I saw foods. And what does so we actually have in it? So soy foods made from soybean planned which are from the P family they are unique mentioned before they contain all nine essential amino acids like animal foods and although plant proteins on nutritious. It does pay to know which plan foods are the best sources of proteins for Children. Who refused meat? So you do want to link back to that previous episode if interest in that topic soy foods. Undoubtedly a nutritious food for kids as they provide good proteins. They provide the such a great source of fiber on and some other B vitamins and zinc. But what really set soy foods? Apart from other plant foods is the presence of i-if Levens sounds good so far right but the potential harm from soy foods I came into question in the nineteen forties when breathing problems in sheep particularly female sheep who were fed a kind of clover that was high. In ice of Lebanon's was first noted and this was when the biological effects of is AFL. Were scrutinized a little bit more closely against volatility. Now you're probably wondering is eleven so if you have a good idea or ready. Let's just look at that a little bit more closely. So soy foods are the main dont resources of i-if Levens for us. They are termed as finer easterns and they have a chemical structure that that is very similar to the human hormone estrogen. Its well established. That in the human body is of Lebanese. Do not behave in the same way. As the you know human form of Easter regions. They are a lot weaker. They only have effects on some tissues of the body and some situation they actually have the opposite effect eastern. So for that reason I would go ahead and recommend soy foods for a boy but I'm going to explain to you wine now. Back in the nineteen eighty s. There were more further damaging findings that surface. The Cheetah's who are fed is of Levin Rich Soy foods in North American zoos experienced a decline inferred Tilleke and two case studies were also published where men experienced problems with fertility. How ever many look through these case studies they consumed honey doses of soy foods and soy is of Levens and followed a relatively unbalanced died so despite these high initial Cannes says a soy is of Florence may have east region like activity a collection of much bigger. Larger Good Quality Clinical Studies. Now show that. Soy Foods actually don't negatively impact on reproductive hormones in men. If you want surprised by that just remember that. These previous lab study showed that saw is of Lebanese do bind and activate to these eastern receptors but the potency is at least ten thousand times less compared to our bodies version of eastern and also. What that means is that song is of Lebanon's are broken down and metabolize and it behaves differently in human bodies. He can't really compare animal. Studies to humans and the lab studies or experiments have use really high doses. Appeal is a flagrant which you gain. You just can't use those lab findings and compare them to human outcomes. I hope that's reassuring for you so if you ask me. The question is soya healthy for boys that short on Z's Yes soy proteins on rich in high quality protein that good source of fiber and there was a habit addition of vitamins and other minerals. Likes think as above soy foods are really safe for boys and men to enjoy as we've spoken about but if you are unsure or you're wanting to just have a genuine discussion and a check of your child's nutrition than Daego had and book that free initial consultation with me. What about the other benefits of eating soy foods so soy foods aren't thought to be beneficial in quite a variety of quite large areas of how it could be beneficial for bone health that are good quantity studies showing that those who regularly eat soy foods? A much stronger bones and are less likely to experience fractious so if foods could also protect you for heart from heart disease because of course. Oy was a naturally low in unsaturated fats at the type of fat. That is more protective for your heart and is less likely to influence the bad cholesterol. Also known as ldl cholesterol so it helps keep that you know the type of Aldea that may be not so good for heart in the normal end of the range. He can also reduce menopausal hot flashes. A great news for women Consuming forty milligrams from is of Lebanese daily. Which is equivalent to two glasses of soya. Milk or hundred grams of Sawyer. Men's could help reduce hot flashes frequency by twenty percent and the severity by nearly a third. That's great news. Additionally women when they are experiencing menopause they do have a higher risk of heart disease. It's almost doubled. And the consuming food is going to be protected or benefit women in two ways of reducing risk of hot flushes or reduce the symptoms of hot flushes. Should I say and also help reduce your risk of heart disease? There's more good information in the menopause. Food Factsheet Search. Just click on the blog post. That I'm good link in the show notes and it'll be defined factually not way also in terms of cancer which I know is very topical and is linked with soy foods. The benefits could be that you could actually experience reduced cancer risk. Although this is not in a confirmed in findings there is some suggestions that those who do benefit from reduced risk of cancer of those people who have had soy food children's as young children in adolescence so eating soy foods in some really doesn't increase your risk of cancer however please do not take any. Soy is a flavin supplements. Stick to eating real
The Big Dilemma Facing the U.S. Healthcare System
"Are we supposed to juggle the cost of medicine? insurance company limitations and hospital economics. If we'RE GONNA try to enhance patient outcomes that is the big dilemma is that we have tremendous standards in terms of healthcare in our expectations that we were going to provide the the best and the greatest and the newest healthcare available to who are patients. And yet we have this notion that this is GonNa come from vaporware that somehow it will be provided to us and and yet we're really at a crossroads a realizing that our Medicare system is straining relative to the dollars that are available Research Searching Development is taking place in the private sector but then the rest of the consumers are feeling the pain because they're having to pay extreme costs in as as far as their medications are concerned and the entire system sort of feels as if it's a row about ready to collapse how can maintain high quality cutting edge medicine and still manage the economics and those two things are so diametrically opposed and so much of our gross national the product is already being spent relative to healthcare and yet we're drowning Medicare's rationing insurance companies are rationing they're hiding the rationing that's going non but there's rationing going on nevertheless so can i. Can I ask this Howard. Does Kaiser have a unique view of how to manage this problem. I think Especially from the point of view Kaiser Permanente we feel that there are some relatively more simple approaches to health care where it's not all just about spending money on the latest when greatest technology or pharmaceutical For example Prevention we in the United States are much more engineered To have patients get great treatment when they're sick but not really engineered to make sure that they get all the preventive care that they should get and there are literally and insurance wise and everyone who say engineered and every one of those ways we first of all. We don't talk about enough. We don't talk about prevention now. We don't advocate enough for it. And we don't have financial incentives centers that favorite prevention or financial. Incentives favor taking care of people. When they get sick we spend a lot more money per unit time for doctorates CETERA? When someone on a sec then giving them advice on how to prevent them from any sick so if we just could get every single American to do the tests and take the treatments from preventive standpoint that we know work that right there would improve health and that right there would reduce costs and that was certainly something we accuse a permanent? They felt very strongly about and had trump have tremendous data. Show that we've been doing. Those things are very very substantial way making sure that populations of patients get their mammograms. Hypertension screens take basic medications occasions. That work for their condition. But you have to make sure that large numbers of patients in the population do it because of all small population percent do it. You won't get the same benefits so one of many countries around the world and in fact we're starting to do it better in this country. No country does a perfectly however In in fact still that's a problem that that's a problem that is actually international nature but Some countries that are doing better at it include Germany the United Kingdom even the National Health Service where people have their criticisms at times about service and whatnot in the NHL NHL does give care. That's very evidence based But no one country has got a monopoly to give great prevention. That's just a huge opportunity for us and everybody else as well let me give you a negative example from this country. We wish I'm noticing Historically we do screening blood tests on patients every year Complete blood count a comprehensive metabolic panel looking looking at kidney function liver function Your Lipid profile your cholesterol your LDL your HDL etcetera etcetera. And historically this has been paid aid for by insurance companies has been paid for by Medicare currently Medicare and then subsequently other insurance companies have followed that we we will do a blood count if you have a blood disorder. So if you're anemic we will justify doing a blood count if he had kidney failure. We'll just we are justified in running your creatine in your kidney function test if you have thyroid disorder than we will pay for that. But if you don't have that you don't have any of these disorders. We no longer pay for routine screening laboratory data. So does that mean that. The insurance companies have not adopted the principle that preventive care actually ends up costing them less than long run to not pay for the screening blood tests will save millions for private insurance companies as well as for Medicare. So how. You're you're you're focused on how we create better outcomes for patients. Isn't this part of the problem. And what do you suggest do we do about it. Yeah so I can at Kaiser Permanente we didn't control doctors ordering habits. A doctor can do anything That they think is appropriate for a patient and we didn't and tell them not to order tests and whatnot but in particular. We strongly encourage them to do things that are evidence based so. If there's a test to be done that would help detect something early. We actually want doctors to do do that. And and have a very good record of accomplishing that. I mean again. We didn't restrict people from practicing the way they felt was best based upon their view of the clinical evidence in the in the patient's patient's condition however it's similar to what happens in government when governmental When when they're tough times and government budgets challenge they tended slash ask things they took the cup? Because that's the only way they can balance the budget so as we get closer to Medicare insolvency and insurance companies are having problems with costs. They they start getting into to cost savings mode and those those cost-saving modes and not necessarily evidence base. So that you stuck maybe cutting out the baby with the bathwater a little bit and don't intelligently try to to figure out what you should do and what. You should not do. What I'm advocating for is to try to use scientific evidence as much as possible to make thorough assessments of these various technologies analogies are tests and then use the evidence that comes forward and make sure people do get these tests are do get these therapies as opposed to basically you want to use this you want to use this information to convince the healthcare economic controllers the insurance companies to think differently about the pro? I do but I also understand. It's it's it's easy to just blame the insurance companies and I'm not here to be an apologist and then you way for Insurance companies or explain what they do again. I'm very proud of what we did in Kaiser Permanente because because we were not just an insurance company also provider of care and we have a really good record of policy but I do think that the opportunities for improving health certainly exists at the insurance level. The exists at the physician level but they also existed the patient
Why Are Macadamia Nuts So Expensive?
"First things first macadamia nuts are not actually ups. Yes I know it's ridiculous. It's right there in the main for goodness sake but much like Brazil L.. Nuts again what is it with. These misleading names. The Macadamia is in fact a seed and although they've become a signature staple of Hawaiian Agriculture Macadamia. His are actually native to Australia. We spoke with Glen Soko an economic development specialist with the Hawaii County Department of Research and development he explained leaned Macadamia. Nuts are originally from Australia but much of the early research breeding work quality development were done by the University of Hawaii on the island of Hawaii. These cultivars are suited for the Hawaii. Climate and do not produce the same high quality nut when grown in foreign conditions cultivars is short for cultivated varieties and these are specific types of plants selected and cultivated by humans. In this case. The plant is a large bushy tree that starts producing macadamia nuts spy the time. It's about four or five years old. So how exactly did these Australia cultivars and up in Hawaii for that you can think. One William Purvis office. Who planted the first Macadamia tree on the Big Island in eighteen? Eighty one purpose didn't initially intend for the tree seeds to be a hit. He planted the trees as wind breaks as for the sugar cane fields. The plants were functional and also happens to be quite pretty but he didn't suspect they could bear such delectable and profitable. See it's about a decade later. One are Jordan planted some macadamia trees on Oahu. The trees that researchers think is the ancestor most of Hawaii's trees and the not quickly became a popular snack among businessmen who came to Hawaii to profit off of sugar plantations in the early nineteen hundreds. The Hawaiian Agricultural Experiment Station was established published to get new crops growing on islands since this newly established United States territory was relying almost exclusively on sugar following the collapse of the coffee market. In the nineteen twenties. The government offered a five year tax exemption on land that was used solely for Macadamia production. But most farmers were interested. That is until roasted it. BECA Damian that's started popping up in stores and consumers went wild demand finance went up and the number of trees planted for nut production more than doubled from nineteen eighteen thirty two to nineteen thirty. Eight sales slumped a bit after that. But by the Nineteen Fifties Hawaii was turning out macadamia goodies to stack fans throughout the world and major companies. Ladies were making a pretty penny off of them speaking of why are Macadamia so expensive while Macadamia is clearly have an interesting past. And they've tastes taste heavenly coated in thick layers of chocolate. Do they really merit they're often exorbitant price tag after all around twenty five dollars a pound. They're considered the most expensive have nuts in the world. So what's the deal. A bunch of factors go into the price but a lot of them. Come down to the fact that Macadamia can't be grown effectively. On the continental dental United States and shipping them in from Hawaii is costly and growing things in Hawaii is costly to begin with because it's a small archipelago that some three thousand miles title. That's nearly five thousand kilometers away from anything in two thousand. Eighteen Macadamia has made the news for a seventeen percent price. Increase which sacco attributed to Hawaii's fixed harvest acreage and a higher global demand. Furthermore Issaquah said it takes seven years for a Macadamia nut tree to produce a crop. Demand remains high and prices are up to a dollar twenty per pound despite this. There's tremendous pressure on the industry. The agricultural labor shortage continues and that's caused wages and benefit costs to increase invasive. Pests continue to affect the Orchard Health and production. The Hawaii land prices are so high. Hi Orchard Expansion is too costly and producers can't wait for seven years therefore the production acreage remained steady despite the increased demand for the nuts. Okay so that explains the cost but are they actually good for you. High fat foods used to be the most demonized of all kitchen staples basically because of a very effective and sort of insidious marketing campaign put out by the sugar industry but thanks to current research and slightly Leila systemic marketing hype such things as nuts oils and seeds are getting their due as healthy options. We also spoke with registered Dietitian than yell. Birger she said Macadamia nuts are high in monounsaturated fats. Low in net carbohydrates and a good source of copper manganese and thion monounsaturated unsaturated fatty acids have been shown to lower. LDL cholesterol levels. The bad kind especially when they're used in place of saturated fats and refined carbohydrates in one's diet it net carbs are important. Consider because it clues you in on how much fiber something contains in relation to the amount of total carbohydrates present. Having we're fiber is crucial to gut health copper assists with iron absorption and transport in the body while manganese and vitamin are central for carbohydrate metabolism. And while all of that sounds sounds great we still live in a society that tends to obsess over numbers. So at two hundred and three calories and twenty one grams of fat per serving a single serving being just ten to twelve nut kernels. and that's just nuts. Nuts dust chocolate are macadamia is really a wholesome snack. Birger said Ed. Although nuts are high in calories they're also packed with fiber heart healthy fats proteins vitamins and minerals essential to our diets. Having a small handful is a filling rolling nutritious snack to tide you over between meals or can be used as a way to round out a meal on top of a Salad or yogurt bowl. They are particularly good substitute for packaged packaged. Ultra processed snacks. Like potato chips calorie-for-calorie. An ounce of chips than outs of nuts are equivalent but the protein and fiber in the nets will keep you energized full. Oh and focused. She said don't fear fats. They're essential for hormone health optimal brain function and absorption of nutrients and end. According to Sacco Macadamia. Aren't just a delicious treat for humans. They can be healthy. Snacks for rodents to he said some pet owners by the nuts in the shell L. to give to the rats to not on this wear down the rats teeth.
Cholesterol levels predict if under-45s will ever have heart disease
"Medical researchers in Germany are touting a new study that promotes the benefits of reducing cholesterol levels starting at a young age to help cut the risk of disease heart disease later in life they found people forty five and younger with higher levels of LDL so called bad cholesterol might want to change their eating and exercise habits or even talk to their doctor about medication women in the study had a sixteen percent chance of having a non fatal heart disease event or stroke by the time they turn seventy five for men the risk was twenty nine percent the study is published in the medical
US panel backs wider use of fish oil to prevent heart attack
"A panel of scientific advisers to the food and drug administration has unanimously voted in favor of wider use of a prescription fish oil pills the medication can help reduce the risk of heart attacks and strokes and there's also not reports it's long been known that omega three fatty acids which are abundant in oily fish such as salmon are good for heart health what's much newer to the scene is a fish oil pill approved by the FDA cardiologists Peter Wilson of Emory University has reviewed the evidence behind the drug is called the sepa this is a prescription product at high concentration this to your assigned fish oil which is extracted from sardines and anchovies is currently recommended for a narrow group of people with very elevated triglyceride levels but Wilson was part of a panel of advisers that was used to weigh in on whether the fish oil pills could also be beneficial for a much wider group of adults including people who've already had a heart attack or stroke and people with type two diabetes who also have another risk factor such as high blood pressure the panel felt very strongly that this fish oil product taken in addition to Statens reduced cardio vascular disease Staten medications work well to reduce LDL cholesterol the so called bad cholesterol Statens can also lower triglycerides to some extent but fish oil can have an added a fax in lowering triglycerides further some prior studies that fish oil supplements that you can buy off the shelf at the grocery store or drug store have pointed to benefits to supplement at lower doses of always been of interest the difference in these most recent studies is using much higher concentrations in the pills in other words smaller doses may help a little but Wilson says to get a significant reduction in risk higher doses are more helpful the evidence comes from a clinical trial sponsored by the company that manufactures the seat back it included people who already had a heart attack or stroke Wilson has no financial ties to the company the trial showed a convincing evidence for reduction of heart attack stroke and cardiac related death about a twenty five percent reduction compared to a placebo group so could people who want to the health benefits of omega three fatty acids just aim to eat more fish especially healthy people who aren't at high risk of heart disease Daria CMOS Afarin dean of the nutrition school at Tufts University says yes for the general population you know I really recommend people eat fish or seafood at least you know one or two servings per week but he says in order to lower triglycerides more is needed the prescription pill is dosed at four grams a day which is the equivalent of eating are you ready for this eight to ten servings of salmon every day that's pretty hard to do you know almost impossible the FDA typically follows the advice of its advisory panels and is expected to decide on expanded use approval by the end of the
US cholesterol levels declined during past decade
"The decline in cholesterol levels among people living in the US it is encouraging to researchers but as the Associated Press the Jennifer king reports many still need care in a study published in the journal of the American college of cardiology researchers looked at records for thirty two thousand adults between two thousand five in twenty sixteen among people taking cholesterol medication the average level of LDL what's known as a bad cholesterol dropped twenty one points over the study period levels of total cholesterol and triglyceride also decreased the study also found an uptick in Staten use points over the study period levels of total cholesterol and triglyceride also decreased the study also found an up tick in Staten used by people with diabetes over the study period from less than half to over sixty percent of the doctors involved with the study cautioned that other high risk groups aren't seeing an increase in treatment and that many Americans don't know if they even have a cholesterol
Cholesterol levels dropping in U.S., but many still need care
"Cholesterol levels among people living in the US it is encouraging to researchers but as the Associated Press is Jennifer king reports many still need care in a study published in the journal of the American college of cardiology researchers looked at records for thirty two thousand adults between two thousand five in twenty sixteen among people taking cholesterol medication the average level of LDL what's known as a bad cholesterol dropped twenty one points over the study period levels of total cholesterol and triglyceride also decreased the study also found an uptick in Staten used by people with diabetes over the study period from less than half the over sixty percent of the doctors involved with the study cautioned that other high risk groups aren't seeing an increase in treatment and that many Americans don't know if they even have a cholesterol problem Jennifer king
Does Plant Based Keto Diets Work?
"For anyone listening the whole idea about adding fat to your plant based i it seems very foreign i mean here's the thing i've been doing this for a number years instead of hosting it out there so that people can see what i do for it to be an option in it's amazing how much push back i get from both the plant as community and the low carb community and it's for different reasons but it's fine i have enough friends in my life that i don't i don't need anymore but your furniture thanks but so you know people think that you can't do it so the low carb people think that you you can't get enough eighteen if you're eating a plant based low carb diet and honestly there are a lot of options and we can talk about those in a second for that from the fats the in point i mean for me it was a matter of there's three macronutrients fat protein and sugar and carbohydrates and if your limiting one of those injuries one or the other and for me i found through experimentation what my optimal amount of protein per day is if i'm going to maintain gene you know i work really hard long hours and i also run a lot like i found what amount of protein i need to sort of maintain my composition and then the fat the things that i added in from a fat standpoint are avocados nuts and seeds i do use some olive oil l. olives cheese flax seeds things like those which for the most part our whole real foods so you know what my they may look like what a meal for may look like is there these beans called lucchini beans that are have zero net carbs they have a ton of fiber or yeah i can use blacks way beans or tofu or hamper some other things like that i also so i can't use the things that have written in them because i wanted genetic lottery that way so i'll have those is my primary protein source and then i'll have a bunch of leafy green vegetables i'll have salad with some olive oil on it i'll put some nuts and seeds on it i eat a ton of broccoli and asparagus and cauliflower and you know put guacamole on everything and hot sauce because everything is better with hot sauce and nutritional he's you know so my diet's it's pretty simple it's pretty straightforward it's mostly wholefood i mean some people argue whether olive oil is a whole fruit or not but we're not going to today i mean olive oil battle far too many times right and at the end of the day every single one of my modifiable markers improved to the optimal range so you know for me and for many of my patients this is way that sustainable and you know i have no objective reason to think that there are downsides in my ANC which is a measure of my control varies between you know four point seven and five point three which is almost unheard of the goal for type one diabetic is six point five five to seven i mean that's amazing i totally agree with you when i when i went into my vegan pita experiment i'll be fully honest full disclosure i was very anti i heat oh diet on forever very anti i like you and i like eat them but it was very much like very not i was hoping he was going to be l. two weeks i was like this is gonna blow up my LDL and then over that span of time in july i was like wait a second to actually read the data read about polyunsaturated fatty acids read about actually talk to different lipid allergists and everyone's like you're limited profile probably won't change at all and didn't if anything even mildly grooved with zero it just felt significance but there was some tiny in prevention so i think that year idea that it can be helpful is actually very clear to me now i know i know tation in ascribe for my each and i think it's i think it's very interesting you know way to eat and have the benefits of the first things i want to start out with you guys a. b. six you guys can go into how do you go into joe says and how you mateen thing he does is just kind of like the basics going into kito animal martha before we do that danielle can i say that i wanna i wanna thank you for doing what you did because it was pretty brave and unusual i think we're all aware this ridiculous diet or detention more thing that happens out there that's frankly just annoying as hell and it was great to see you try this and admit that you went into it with a not such an open mind and then admit that you really had a better experience than you thought you were the product of that has been tremendous i mean first of all it's brought the three of us together in a way that none of us expected it's been fun and we'll talk about all that later but it was really awesome that you did another carries like wait i've been talking about this for five years old sudden danielle opens her mouth and like the whole vegan kita i thank you i think it's for me at like i think that i've just been i tell you over the past two years i've realized how complex obesity isn't free conceicao kind of explain understand how key johnson precipitate but for anyone listening it works i mean maybe doesn't work for everyone in mountain state that everything everyone but for me like i had really great and i think that it's something that once you experience it you can't unknow it it's really interesting experience it works for people that want to try it so yes most people have been asking these kind of the basics you could just kind of describe how do you go into toes says on the whole you know there's like a lot of myths about you can't have any carbs where i kind of to sell zavos society to is it is significant when you're in ketosis that you know i used to think you had to be a special kind of stupid to miss a meal because all i could think of that was wanting to eat all the time and when i'm in ketosis which is now most of the time i have to remind myself to eat like i'll operate all day and then not eat until you get home from like this i have actually not looked into this there's something about the key johnson actually suppress like what is the what is the actual mechanism of up yeah need maybe ethan you can talk more about this there's different theories on it i don't know that anybody fully understands how it impacts the different hunger hormones i think there's sort of a theory behind ended at you know if food was in scarcity and we were hungry all the time we would not work communal species than we would not get along very well if we got you know we're perpetually angry until we found food but i i don't think anybody fully understands the mechanisms how it impacts the hunger hormones specifically but those questions are being asked yeah there have been so star if you start at the beginning there are definitely there've been randomized controlled trials to look at appetite and society and every other measure of hunger her absence of hunger and i think there's no doubt that on a proper peter jennings diet that hunger is reduced versus other diets i think people believe that i don't think we understand the anisim and i think as carrie alluded there are lots of studies looking at potentially the role of grellet or other hormones that affect appetite might personal favourite theories it has something to do with insulin but i'm sure that's not all of it and to be just circle back to your question before about whether or not it's key tones itself or its carbohydrate restriction or something else we don't know it could be any of that MR all of them it's interesting i notice a definite difference i think up to save nutrition show individualized but i do think about on some level is because i think there's some people who can eat and i normally do i normally might like regular diets like gazillion grab carbohydrates damn fine but i am kind of always hungry i've never experienced the feeling of being like not hungry at all until it was just it's like i've never felt like shocking i think that's the most common thing that i hear from people who started for the first time is that there is i feel like they're never hungry and you know some people think it's just you're eating all this fat and fat has various at satiated and again there are like one hundred fifty theories and it needs to be worked out why but i think it's pretty clear that the the flip difference i mean i don't think it's the fact that you're eating because like i said i can have my last meal at six o'clock at night and i can go until six o'clock the next night in have operated the whole day it's not like drinking butter for breakfast and that's the reason why i'm not
Will combo pill catch on in U.S. to prevent heart attacks?
"So will a combo pill catch on in the United States to prevent heart attacks interesting story I want to get from doctor to listen here's this story today I cheap daily pill that combines for drugs has been tested for the first time in the United States to see if it works as well among low income Americans as it has in other countries to treat conditions leading to heart attacks and stroke the results published Wednesday of this last week so just a couple of things in their study and that it can lower blood pressure it can someone help with bad cholesterol experts say the study may draw U. S. interest may draw US interest Dr in a strategy that has been as useful only in places with limited access to medical care a cheap daily pill articles experts say the study may draw from things about three hundred people ages forty five to seventy five doctor G. from a community health center in mobile Alabama took part half were signed to take the combo pill the others continued their usual care after a year the poly pill patients have lowered their blood cholesterol and LDL and bad cholesterol by more than the others and by amounts doctors find meaningful it's a long way out from probably getting FDA approval on this what's your ten thousand foot view of this bill her doctor G. I don't know that such a far distance away okay okay because each one of these pills in the poly pill in there have to be four components to it here. is the unapproved drugs you know they didn't just go and get a bunch of stuff that nobody's ever tried before but putting it all in one pill especially in multiplicity like this okay I got four things in there you know how you gonna keep track of all right odd that's been the thing that's where the government in the past there are other countries were Polly pills are accessible and they are cheap they cheapen the the cost of the medication and they also make it easier for you to take the Medicaid right you know getting the pills all lined up every night or every morning and you know dealing with that and can't remember where you took both of them or one of them or two of them you know those are really really important things and the cost is the biggest for sure right because if you put four pills in one and I think they were gonna have a cost like twenty nine Bucks or something like sure that's far cheaper than each one individually yeah the question is you know some people need more control of their blood pressure some people need more control of their cholesterol yeah so who gets what here and there are places where these kind of medications are given for one disorder like high blood pressure but they'll just throw in a an added component to lower your cholesterol knowing that both of those are risk factors yeah did then actually your cholesterol can't be too
Cutting 300 Calories a Day Shows Health Benefits
"About to how many calories a day do you need to cut from your diet to get significant health benefits here Scott Kerr intermittent fasting or skipping that slice of cheese cake for dessert is about all it takes is the authors of the study published in the journal the lancet Duke University professor and senior author William Krause says an average reduction of three hundred calories per day by study participants lower their blood pressure as well as levels of LDL or bad cholesterol in the first year and resulted in a sharp twenty four percent drop in concentrations of triglycerides the type of fat and the blood that raises the risk of heart disease the study is the first of its kind to look into the potential impact of calorie restriction on the cardiovascular health of healthy non obese young and middle aged adults I'm Scott
Cutting Just 300 Calories Per Day May Keep Your Heart Healthy
"Duke University professor and senior author William Krause says an average reduction of three hundred calories per day by study participants lower their blood pressure as well as levels of LDL or bad cholesterol in the first year and resulted in a sharp twenty four percent drop in concentrations of triglycerides the type of fat and the blood that raises the risk of heart disease the study is the first of its kind to look into the potential impact of calorie restriction on the cardiovascular health of healthy not obese young and middle aged
Cut Just 300 Calories a Day to Benefit Heart, Even in the Healthy
"Fasting or skipping that slice of cheese cake for dessert is about all it takes a the authors of the study published in the journal the lancet Duke University professor and senior author William Krause says an average reduction of three hundred calories per day by study participants lower their blood pressure as well as levels of LDL or bad cholesterol in the first year and resulted in a sharp twenty four percent drop in concentrations of triglycerides the type of fat and the blood that raises the risk of heart disease the study is the first of its kind to look into the potential impact of calorie restriction on the cardiovascular health of healthy non obese young and middle aged adults I'm
White meat is just as bad as red meat when it comes to cholesterol, study says
"Wanted to get to the health news. Because this affects a lot of people, okay? A lot of us think eating chicken better for you healthier heard that for years, eat chicken hotdogs Robbins. Yeah. The other day I was. Yeah. Turkey hot dogs Turkey, and chicken dogs, any type meat that's chicken, or Turkey outstanding. But this might not be working in this story. They say Naven know you've heard it for years. Eating red meat is bad for your collection. Right. So you might want to eat more white meat like chicken. Well, there's a new study just published in the American journal of clinical nutrition that says there is basically no difference when it comes to cholesterol. In the study, this is involving one hundred thirteen people people taking part in it. Eight three different diets over the course of three months, one that was either rich in lean cuts of beef lean cuts of chicken or Turkey or plant proteins. Now, plant proteins, of course, blue both out of a blue all three out of the water or the other two out of the water. The researchers measured the diets effects on LDL cholesterol. That's the bad cholesterol only plant based diet actually lowered those levels. So the result can be viewed as indicating either a cholesterol, raising affect the Meads, a cholesterol, lowering effect of plant foods or both. However, but when you look at the white need versus the red meat, they said there wasn't really a noticeable difference. Gosh, dang it. So just go ahead. And get that
Both Red and White Meat Raise Cholesterol Levels, Study Finds
"Well, it's something we've been told for years at white meat is healthier than red meat. New study shows, maybe not turns out, it does not matter, whether you eat red meat or white meat both have the same effect on blood cholesterol levels. The university of California, San Francisco study found that plant proteins had the healthiest impact on blood cholesterol, the effects of white and red meat's on participants cholesterol levels were identical. When saturated fat levels were equivalent. So. So no matter their source of protein, participants eating a high diet in saturated fats had higher LDL cholesterol levels than those signed to a diet low in
"ldl" Discussed on News Talk 1130 WISN
"We're going to be given out that phone number. Jason let's get to ingredient number two because this'll make a three super pill. Does something that no other fish oil product can do and actually lowers cholesterol talk about these plant sterols, explain how this works. And why it's so important, right? Well, I don't know anyone who isn't concerned about their cholesterol. If you have high cholesterol. Obviously you wanna lower it. If you have normal or healthy cholesterol. Obviously you wanna maintain it. Well in the world of dietary supplements there is one compound one ingredient that stands head and shoulders above anything else. They're called plants. They're all they have over a hundred and forty human clinical studies shown to lower fig -nificant, lower LDL cholesterol, and again, LDL bad cholesterol, HDL good cholesterol. Right. So obviously, you don't wanna lower HDL. Plant sterols only target LDL. And the studies are pretty dramatic. They show that in as little as a few weeks four weeks, you can see anywhere from five to fifteen percent reduction in your LDL level safely, and naturally absolutely no side effects, very effective. They've known about plants they're all since the nineteen fifties, and they work via a very different mechanism than statin drugs. So I wouldn't tell people to stop. Taking statin drugs. We're not trying to position this is an alternative to statins. Statins work by preventing the production of cholesterol in the liver. Plant sterols work differently. They block the absorption of cholesterol in the intestines. Plant sterols are similar structurally to the cholesterol molecules, and they basically confuse little sales in your intestine called my feels into thinking that the plant sterols are actually the cholesterol particles. So the my steals pick up the plant sterols instead of the cholesterol particles, and the cholesterol particles instead sort of just get passed through your intestines in you, ultimately, excrete them instead of absorbing them. The point is if you're on Staten, you can take plants they're off as an addendum therapy to help control your cholesterol. Studies actually have been done to show that they can amplify the benefits. And of course, this particular product, you get obviously first off the full clinically. Tested amount of the plant sterols to deliver the benefits as shown in the studies. That's something that's very important because a lot of products out there that you'll see that have plant sterols on the label may only deliver a tiny fraction of what any study is ever showed any benefit for purity delivers the full amount that you need to get these benefits. Now, Jason let's talk about the third ingredient in the formula co Q ten which is also becoming one of the more popular nutritional ingredients all over the world. Tell us about co Q ten and why it's valuable for our health. What is it? What does it do? Well, co Q ten is found in every single cell in your body. If they're from the moment, you're conceived until the moment, you leave the earth. Unfortunately, as you age, you lose coenzyme q ten so by the time, you're in your senior years, you've only got about half as much co Q ten as you did when you were about twenty now when you think.
"ldl" Discussed on 710 WOR
"To the all new sick and tired of being sick and tired. I'm Rachel ash here with my co host ashed center medical director, an internist Dr Alison pied ditch when we are talking about cholesterol before we cut to the commercial break, Dr Alison was sort of debunking LDL, quote, unquote, bad cholesterol. What it is. We talked about how it's not so much the quantity of it. But the quality of it which really can affect your arteries anything else on on LDL. So why I'm discussing this is that I always see patients come in. And they're like my doctor put me on a statin because my LDL was like one forty one fifty. It was like a few points a little high and in general medicine conventional medicine, they don't really have anything else in their bag of tricks as I say to do for people when their cholesterol, slightly elevated one of the things that's. So important is that you can have your LDL elevated, but it's not necessarily bad. Right. There's there's all these different versions of LDL, which we don't we haven't really been checking over the last few years, and we are now. So we know that slightly elevated LDL may not be bad. You may have normal LDL and actually be very high risk for heart attack. And how we know that is there's different types that we can measure now, there's something called in April be I'm trying I'm not gonna wait you guys down too much on the terms, but they're sort of like a protein that the LDL's attached to now that we know if you have too much of that protein, it makes LDL very sticky and very sticky to the inflammation in your arteries. If you have the small version of LDL, so very tiny particles a tiny particles, obviously more likely to get stuck in those cuts in your arteries than the big particles. Very other things are there's certain types of LDL that you genetically inherit that. It's. Called that. You're more like that are much more dangerous and stickier than all of the other ones. So there are more likely to cause plaques when there's inflammation than the then the then the the type that you're taking it in your diet, right? The other type we know is there's oxidized LDL. So oxidized LDL is the actual bad cholesterol that has been stuck in plaques, and the sort of when you have some plaque rupture, it kind of floats out and flits around your body, and we can measure, then say, okay, you, absolutely. Even though you're LDL may not be super high. You have plaques in your in your arteries that we need to we need to address. So when a patient comes into see you or a functional medicine doctor. They are typically able to measure this and really figure out what set of just measuring LDL measuring an mentioning just a minor part of the test. But there's at least twenty different LDL's. I'm measuring on you. And these are just sort of the bigger ones says through this. You're able to have the information to figure out specifically. What your unique biochemistry, and what would be the best treatment for you rather than just blanketing? You. You guys. I have a lot of patients who come in with elevated LDL's, and we do this measurement these measurements. And they're totally fine. Yeah. They they don't have they have large LDL particles that can't get really stuck in these inflammatory plaques. They're just slightly elevated, and that's it and they just move on with their lives. They don't need to be on statins. Yeah. And there's a lot of side effects of statins to it's something that people end up suffering when they're on them for long periods of time. They do they can treat things in other ways without using occasions. Talked about oxidized LDL's. What do we always talk about the centers, inflammation and anti-oxidants, right? So antioxidant oxidized LDL so antioxidants literally will eat up oxidized LDL and lower in your blood and we've seen that with vitamin C, especially the the oral supplement from pure essentials and the vitamin drips with high dose vitamin c in them. They have taken. Oxidized LDL's which I've seen in one hundred hundred fifty and lowered to twenty or ten amazing just a few months, and Dr able to do customized IV's for her patients based on their blood work based on really be able to get this specific minerals that they want with pure essentials. There's some amazing products that we're able to use for anti inflammation from our buffered vitamin C Earl tra- corset, and we do have an antioxidant homeless co Q ten. But they're just exceptional products. Absolutely. It's a cornerstone any accents are cornerstone of pure central's in what we do at the center of everything creating anti inflammation and a healthy body environment. So seeking of of healthy and good. We hear HDL so good. What what what is this? And what does this mean? Okay. So HCL is actually called high density lipoprotein, and that's considered are good HDL. Why did we call it the good ones? So it's what we call cardio protective. And it literally we say cancels out the LDL. So what each Seattle does is you have sort of these little kind of like balls of LDL floating through your blood and each gel, actually like eats. It. And helps you get rid of that LDL from your body. That's what you just yell. Does. What's our goal? It's over sixty and your bloodwork is what we call optimal. Protect. Yeah. So it's protective level if it's under forty it's actually just as bad to have low HDL as it could be to have these bad versions of LDL. Well, okay. So that's something. That's brand new. That's come out in in cardiology research that low LDL Earl sorry, low HDL is very very bad. Okay. And that's something that we haven't been aggressive with at all. We've only been very aggressive with we have to lower LDL we have to give stands and lower LDL. Right. Right. And so what it's shown is that only the very large HDL particles are what are cardio protective. So they'll only the very large particles and there's five versions of this particle, and we call them out for one two three four or five. Not that important, but this alpha one particle what the research is now showing is that if you don't have enough of this alpha one HDL particles, so this high sized shell particle, it's the most significant predictor of heart attack. And this is something they said. Right. And this is also something that you'd contest for absolutely. So so we one hundred percent test for this. So this is more significant than having all of those LDL's that I just talked about all those bad versions of those LDL's. This is more significant. And that's also something that you don't get tested for and can national medicine absolutely detested for so you can be tested for each jail. And they're like, oh, you're good. You're you're like around between forty forty five you're fine. And that's it. But if to know if you have this alpha one radio, which is significant predictor, you really need to go see a functional medicine doctor like Dr Alison. Yeah. What else? Do we need to know about HDL? Well, what I can tell you is improving. So we know improving HDL is can be more important than the foods that we think can increase your LDL. Right. So this is sort of goes back into the play about the eggs is that. Okay. So eggs may slightly increase your LDL. It's probably not the bad LDL. Right. And what may be more important is not necessarily worrying about the level of the LDL? It's that let's really focus on pushing the HDL up because that's really what's very protective. So it sounds the HDL LDL really need to work hand in hand. Right. So there's I'm getting us. There's ratios and things of what would be a proper balance of the HDL a very simple way. So without coming and seeing me or seeing another integrative physician is check your ratio of total cholesterol to HDL. Basically, what you do is you divide the total cholesterol by your HD. AL level. And what we want to see is an optimal ratio somewhere between three point five and one now if it's higher than that than that showing up pretty high risk of heart disease. Well, that the basic on HDL an LDL we hear about it all the time. We didn't really know what it was fully until now. So thank you Dr. And that was really helpful. Let's talk about something else that's included in this whole topic, triglycerides. It's another so that we're we're all right. We'll be done for you. Don't know what it mean. I hear your elder LDL HDL levels, triglycerides level. What is what are triglycerides? So why are they important so triglycerides, and you know, what triglycerides usually fall to the wayside as well too. Because statins don't really affect triglycerides levels very much. So doctors user, just like, oh, your triglycerides are a little high. And that's about that's about. It. Just watch yourself. Watch your diet. Like, that's usually what we say triglycerides are basically the chemical form of fats in your body. That's how fat exists in your body as a triglycerides. So it's when we eat foods to triglycerides are the food fat turns into triglycerides floating through your body's. Okay. Okay. Optima we want it below one hundred and fifty in our bodies when we see going above a hundred and fifty and up to two hundred we know you have a very high risk of heart attack. And so that's separate from it's sort of it's sort of an indirect approach. So you can we know now that triglycerides actually help make small the small density LDL's, those are the ones we said that get stuck in plaques and get stuck in inflammation in the body. It also when you have a high triglycerides in your body. It also lowers each HDL right for some reason it somehow tax each. Pl industries each del Rey. So all these things really needs to be harmony as absolutely that's I think that's what I'm trying to get to. And that's how many words. Everything needs to work, and you need HDL, you need LDL you need, triglycerides. But you need them inharmonious harmonious healthy levels. Right. Absolutely. And so what could be more important as your triglycerides may they're saying now like that may be more important than your LDL levels. Right. If you have high triglycerides levels, you're going to have bad LDL. So one thing affects the other. Absolutely. You can listen to us on iheart media. If you want to go back and hear that again, we are online with that..
"ldl" Discussed on News 96.5 WDBO
"We're going to be given out that phone number. Jason let's get to ingredient number two because this make a three super pill. Does something that no other fish oil product, can do it actually lowers cholesterol talk about these plant sterols, explain how this works. And why it's so important, right? Well, I don't know anyone who isn't concerned about their cholesterol. If you have high cholesterol, obviously, you wanna lower it if you have normal or healthy cholesterol. Obviously you wanna maintain it. Well in the world of dietary supplement there is one compound one ingredient that stands head and shoulders above anything else. They're called plants. They're all they have over a hundred and forty human clinical studies shown to lower significantly, lower LDL cholesterol, and again, LDL bad cholesterol, HDL good cholesterol. Obviously you don't want to lower HDL. Plant sterols only target LDL in the studies of pretty dramatic. They show that in as little as. A few weeks four weeks, you can see anywhere from five to fifteen percent reduction in your LDL level safely, and naturally absolutely no side effects, very effective. They've known about plants they're all since the nineteen fifties, and they work via a very different mechanism than statin drugs. So I wouldn't tell people to stop taking statin drugs. We're not trying to position this as an alternative to statins. Statins work by preventing the production of cholesterol in the liver. Plant sterols work differently. They block the absorption of cholesterol in the intestines. Plant sterols are similar structurally to the cholesterol molecules, and they basically confuse little cells in your intestine called mice feels into thinking that the plant sterols are actually the cholesterol particles. So the my steals pick up the plant sterols instead of the cholesterol particles, and the cholesterol particles instead sort of just get passed through. Your intestines than you, ultimately excrete them instead of absorbing them. The point is if you're on Staten, you can take Lance. They're all as an addendum therapy to help control your cholesterol. Studies actually have been done to show that they can amplify the benefits. And of course, this particular product, you get obviously first off the full clinically tested amount of the plant all to deliver the benefits as shown in the studies. That's something that's very important because a lot of products out there that you'll see that have plant sterols on the label may only deliver a tiny fraction of what any study is ever showed any benefit for purity delivers the full amount that you need to get these benefits. Now, Jason let's talk about the third ingredient in the formula co Q ten which is also becoming one of the more popular nutritional ingredients all over the world. Tell us about co Q ten and why it's valuable for our health. What is what does it do? Well, co Q ten is found in every single cell in your body there from the moment. You're conceived until the moment you leave the earth. Unfortunately, as you age, you lose coenzyme q ten so by the time, you're in your senior years, you've only got about half as much co Q ten as you did when you were about twenty now when you think.
"ldl" Discussed on Dishing Up Nutrition
"So next Saturday on dishing up nutrition Kara and Shelby will be talking about nutrition to ease headaches and migraines. So we'll look forward to that show. Yeah. That'll be great. So just to recap we've been talking today about cholesterol numbers. We've talked about triglycerides talked about HDL and starting to talk a little bit about LDL here. So over fifteen years ago research found that sugar increases are LDL levels previously. We had been told we had to reduce our fat to reduce those LDL levels. But that's not true. It didn't work for me. No me, either me either. So. Yeah. So there there is more to that story and Caroline's going to explain more, right? So when we talk about LDL cholesterol, or that low density like a protein, there are so many layers of information. So first of all what is the accepted LDL range? Generally, the accepted range level is below a hundred and thirty that will put you at a very low risk. But it really depends on what type of LDL cholesterol, you have. So both HDL and L. L cholesterols are made up of different particles. So if you are concerned, it's really best to ask your doctor to run what's called a particle test to determine if you have the lightened fluffy LDL and some people do right in those LDL numbers are high in their get concerned. But if they have the light and fussy that's not bad. That's kind of the good LDL. But you could also have those small dense LDL particles and those are not not so good for your for your health. But I have found to hand that some doctors just refuse to run this test. Right. So you know, what about have you got a grants? Yeah. I agree. And I know a lot of peop- and people just don't wanna pay extra for more tests on their own or maybe don't even know they have that option. Yeah. But then. I say to people. Okay. So you're gonna start taking a Staten. How much is that gonna cost you, and what's your deductible or whatever? And then we kinda reason it out, and I say, okay, maybe it's worth running this one test. Yeah. If you can so also too. If you do have those light fluffy particles it does reduce your risk. But if you have the small dense LDL particles that are oxidized in inflamed, you are at more risk. So when you think of LDL and HDL cholesterol, the LDL carries kind of that ready to use cholesterol molecules or particles to be absorbed by the cells that need the LDL cholesterol. We need some LDL cholesterol. We do and the HDL actually picks up that excess cholesterol and carries a back to your level liver. For recycling and excretion. So the HDL end the LDL actually worked together to keep us healthy. That's right. And I wanna finish up. Our discussion about cholesterol today by sharing some surprising information, most people think LDL is a bad cholesterol. But the reality is LDL cholesterol is really not bad at all. It actually has many functions in the body. So in past shows, we've talked about having healthy cell membranes. And how that is important are LDL kit cholesterol, carries beneficial nutrients to all of ourselves. So we need some of that LDL right yell is a carrier of those good nutrients Elliott cholesterol, also helps to make cortisol and estrogen and progesterone and test. Saas thrown those are all important hormones. We need LDL to produce our hormones..
"ldl" Discussed on The Obesity Code Podcast
"I ask melissa if she's talk to the doctors in the nurses about low carb and did she get anywhere i've tried i have one doctor who's actually eating a low carb diet now um and then the other ones just ask for the studies but they're not really interested in the studies it's an odd it's an odd thing because again i've been reading a lot and listening a lot and they say that physicians get about three hours of nutritional training and medical school and it's doctors just want to write prescriptions and i have friends at her doctors and they work for great doctors but they really just want to write the prescription the problem with most doctors now they're just really not up today we've been talking that total cholesterol ldl hdl cholesterol but it's just sick lipid markers have and our understanding of them have moved have earned a standing has just vastly grown in the last 10 20 years it's just it's just hyper linked forward as we now understand the most meaningful risk factors for heart disease the low carb diet really improves all of those ldl cholesterol that's the kind of sticking point one low carb diet s tend to raise people's ldl cholesterol the bat the socalled bad cholesterol well here's something must people understand ldl cholesterol does not track well with your your cardiovascular risk in the studies where they actually look at to see who dies it's never related to their ldl cholesterol level so ldl cholesterol turns out to be super poor predictor of cardiovascular risk.
"ldl" Discussed on WCBM 680 AM
"129 one tony nuts of so they there is no here now here we go he of questions on clean bagged overcoat across sort of was in two twelve light exactly as i wanted to ask you dr what about the 'cause you talked about this before about the size of the particles of the of the y'all deal is that something that he should also consider well i mean if you want you to be a real perfectionist out whether or not who has the types of kousei here's have ldl cholesterol one hype aid one hifi children forget it type so let's just talk about the size if you have a smaller sized ldl particle genetically you are more prone nizzola thing atherosclerosis as opposed to a larger size ldl particles you can actually look at the particle size and sub categorize yourself into whether or not you have a higher risk or a lower risk but the point of the fact was that you stop eating red meat and your cholesterol didn't really change that means that it is not it's not diet driven it's actually genetically so eurogenetics sort of indicate where you're going to be in this spectrum of of uh your cholesterol metabolism and let me just tell you something you are doing excellent you're in great shape uh if you wanna give yourself a little boost the level ldl as well as the ldl x 210 those are the two products that could additionally lower your cholesterol uh and lower your ldl cholesterol as well as your total cholesterol increased your hdl cholesterol because i need she'll crustal of fifty is great but an hdl cholesterol.
"ldl" Discussed on The Obesity Code Podcast
"With sixteen international scientists we did a systematic review looking at people aged over the age of sixty specifically and the association of ldl socal bad cholesterol and heart disease the reason they chose people over sixty is because most people who have heart attacks are over the age of sixty and what we found in his publishing bmj open and he made news in the uk i was pretty extraordinary we found if you're over 60 there was no association no association whatsoever between ldl cholesterol heart disease an inverse association with allcause mortality in other words the higher your ldl the lesslikely you are to die if you're over 60 as we know class from us oh me functions in the body the already essentially we die without trust or whether it's maintaining the integrity of cell membranes hormone production urological function but one of the other team uses if you've eichel unip why class was important is also is involved in the immune system and it's thought that actually in the people with higher lvls who are elderly a protected against life threatening factions such as pneumonia which is wealthy people in a vulnerable to and can die from wait a minute i thought high ldl cause heart disease wasn't there some study that showed that when you look at the original association studies framing this population in massachusetts photopher decades the motive studies done on those on the population can cluster was risk factor and i only discover this relatively risk recently arthaud this really interesting.
"ldl" Discussed on WCBM 680 AM
"The morning you're eating too much sugar and it's depositing itself historic fat and that's what triglycerides are and there's a faction of ldl cholesterol and that's subfraction of ldl cholesterol is cold uh if if either you have an ldl cholesterol particle size that large which is a better particle size to have than a very small one so there's a subdivision of ldl cholesterol if you fail myopia of questions borderline uh but i am i still at risk for having heart disease or you can get a free subfraction coal subunits of the cholesterol and she end the smaller the ldl particle is the worst so this type a and b and and one is very atherogenic which is the smallest particle so if you have large lvl particles you're not as i'm not as concerned is if you have smaller ones and so those are the numbers no your numbers no you inflammation no that you see r key levels have to be less than two one is perfect less than one is even better greater than three quits you at risk for developing further cardiovascular have because of the information that's going on in your body forget let's take a phone call here sambas a insults in this morning tom good morning you're all the doctors you bureau good morning dr um i have a question i try uh the race and i can't tolerate kick tell you that may uh i normally uh my cholesterol saaf it's never been a problem by this persistently on the upper shy uh so i actually i tried to rice but i can't tolerate what are your thoughts what is what is the red yeast rice what it how can you not tolerated what is it doing i actually i came came internally and uh so uh i fact off on now if i may uh i'm taking um uh hdl floss and it also take uh level pl uh excellent good i'll go down i mean what you numbers are now give you a little bit of insight i apologize i don't have him okay so do you so you have a total cholesterol of both two hundred or now now now come on down uh now it's it's it's it's a wolf is not noise it's easier normally a little bit above normal okay how is your hdl uh i'm sorry i can't check how are.
"ldl" Discussed on WCBM 680 AM
"Yeah that's the other point that would walk in glamoc tori respond so at the information that happened is there is no component could correct krone have to really understand that correct wrote a waxy upton it get cramp through the body by the rifle protein lipids and proteins come by one of them hold ldl cholesterol and the other one is cold eco cholesterol and and there's also a word fat and lifted triglycerides so what happened is that if you have a high component of ldl cholesterol ldl cholesterol oxidized it undergo transformations something the body accent graeme hick and it becomes very after tanic atherogenic moon that it does could a world of the endo fealey unwinding of all of our blood vessel we talk about heart disease recalling about heart disease right now but it could and blood that on your body you're a order the arteries going up to your brain the artery got pride blood to your could move your liver so it's everywhere throughout the entire circulatory system when ldl is oxidized and a wall of the artery is a paid up in glamoc tori so that a act it and it christ to sort of quick active from going further but what happens is when the levels up persistently elevated it get further and further it's like a bombardment of of of just go that attack the in aligning of our blood vessel and it opens up an area that cram one now that rao request to move in to the sort of you know layers of the artery of our body and and that's where the inflammatory response at one point is protecting us but at the same time it's also uh if there's a lot of information going on and there's a lot of high levels of cholesterol it gets into that blood vessel and it's start developing in a afro gen a crack on or or and the term is obviously atherosclerosis after it that self in there and then it actually changes on tour our arteries and the ability vied narrows augurs because it fold is out into the woman and that's really what sets you up to a potential to develop a heart attack which is a easier enap crack get then get the tac by platelet then course a caught so you're absolutely right that.
"ldl" Discussed on WVNJ 1160 AM
"Pannella just looking at your cholesterol what's the total what's your ldl number what's the v ldl what's the hdl what's your triglycerides but if you look at the particle size this is going to let you know okay you have this much ldl but out of that ldl this much of the ldl is less risky because it's package in these big fluffy particles whereas if you have an abundance of these small ldl particles those are more problematic and because they can get wedged into blood vessels and do damage this is why we talk about inflammation and inflammation being that primary driving force for cardiovascular disease as well as every other chronic disease that exists inflammation is your underlying enemy so uh what did they look at your at penn state well they did a um a study here looking at let's see me pull this up so they said it was a controlled feeding study sounds interesting a a controlled feeding study of men and women who had elevated ldl so that's the bad remember elfor for lousy ldl cholesterol and they participated in a two two different feeding studies one was six weeks the other one was six weeks oh looks like they twelve weeks total here and during one of the the feeding they gave them almonds and they were giving them about a handful they said of almonds a days that's roughly prime eighty twenty almonds and the they found that when they compared how they did with the diet that consisted of daily almond intake versus the period were they were giving them banana muffins which i'm were extremely tasty for that sixweek time period they looked at the difference in how their co leicester all levels were and sure enough they found that those who incorporated the omens into their diet had multiple benefits including all of these different measures that there were looking at 4 h e l and lvls the ldl level was going down the hd a level was going up so really kind of interesting this is they they said they said the researchers found that compared to the control diet which consisted of the banana muffin on the allman diet increased hdl when the particles are at their large of size and most mature stage the.
"ldl" Discussed on WVNJ 1160 AM
"That tap that i told you about as a way of ensuring that they are actually was a benefit so this is an end to theo am the three in reminding of the bug that both the triptych lipik fat kept the supplement from turmeric curcumin uh here was another study that found naggar cardiovascular railway aidid benefit with eight weeks at supplementation with curcumin and what happened worked with decrease in here on levels of triglycerides and ldl cholesterol and this time it was not in healthy people it was incapable that had coronary artery disease there we talked about long happy people we've talked about older people found healthy come not and now we're talking about people that actually have coronary artery disease and then it was reduction of triglycerides and ldl now cholesterol so this is something that is uh uh really important it was a hundred people and they had metabolic syndrome and it with a thousand milligram dose of curcumin and it with an eight week treatment period so this is done in a hospital it was only thirty three people um but they all had coronary artery disease and there's a significant reduction in khiyam level of ldl and triglycerides there is also decrease in something called the el al or very low deputy lippo protein that are arguably even more dangerous than out so what we're talking about here are benefits to the help of the lining of the blood vessel benefit to enhancement of the the arteries to be able to dilate away and in response to paul food of blood flow because that's what we're talking about when we have our curiel gift now we end up with high blood pressure because what happens is body you're still trying to push the blood the real but if you've lock the eur deputy then the blood ruffled government dial late and with each beat of the heart the call of blood volume is coming through pushing against the blood vessels the heart work harder when that happened blood pressure elevate when that happens who when you have a good healthy blood vessel when we have good healthy tissue lining the blood vessel you're less reactive two directors on that i mentioned that high fat me over a double cheeseburger with progress in the milk shake being a director on flow mediated dilation on the ability of the blood that.
"ldl" Discussed on NEJM This Week - Audio Summaries
"Multi variable analysis involving thousands of patients in these large randomised trials will probably identify subgroups of patients who will benefit from on pump or off pumped cabbage it is time to change the discussion and choose the procedure that is best for the patient cognitive function in a randomized trial of evola q mab by robert giuliano from brigham and women's hospital boston findings from clinical trials of pro protein convert tastes subtilis in kexin type nine pcs k nine inhibitors have led to concern that these drugs or the low levels of low density leipold protein ldl cholesterol that result from their use are associated with cognitive deficits these investigators prospectively assessed cognitive function using the cambridge neuropsychological test automated battery in a subgroup of patients from a randomized trial of evola q mab added to statin therapy a total of one thousand two hundred and four patients were followed for a median of nineteen months the mean change from baseline over time in the raw score for the spacial working memory strategy index of executive function the primary and point was minus point two one in the 'evil lock you map group and minus point two nine in the placebo group there were no significant between group differences in the secondary and points of scores for working memory episodic memory or psychomotor speed in an exploratory analysis there were no associations between ldl cholesterol levels and cognitive changes in a randomized trial involving patients who received either ever lock you mab or placebo in addition to statin therapy no significant between group difference in cognitive function was observed over a median of nineteen months.
"ldl" Discussed on WTMA
"Actually that are high ldl as bad no more sat right there needs to be lowered it here's a thing this isn't the whole story so ldl as bad is like saying that anything that you eat that is sweet is bad well here's the thing that's not the whole story so there was another study that compared modern we to give you an example this to actually hole like whole oats k and what did showed was that if we actually take modern we compared to like hold old sir now the form of an oatmeal ed showed that we raise your ldl particle by more than fifteen percent more and what's called your small smalldense ldl which is actually the most dangerous because that's actual causes a lot of plotting it actually the whole wheat actually created were mieno made that small dense ldl increased it by sixty per cent compared oats this is insane so you know modern we you know products they drastically increase the risk of cardiovascular disease and at least when we look at at comparing it to older we remember we said the 1970s they started kind of brit brett a breeding this bread together kind of like you know a tough were to say her you know breeding bread but that's what happened was you know so we we see these other grains like oats are dealt the can be better for you because they're not raising that some all ldl which are the dangerous particles okay now this is something you need to know especially because the small ldl is can can clogged arteries okay and it's the big ldl cholesterol i'm actually does nothing of that kind of sorts so you we kind of talk about this you obviously ally this comes back to inflammation now the great thing is inflammation can be fixed through nutrition okay but that's what we're all about here obviously ripe but you here's their thing is to is that there are other factors that can trigger inflammation the next thing is we have to look at is that you know for a lot of us you know why did a lot of us you know maybe eat the same thing in one bodies able to he on one's not will the thing is to his we have to look at again what is our what is our body even use to heal inflammation you know in your body hagan has a number one healing agent and here's a thing it's the oregon the controls your entire body and makes.
"ldl" Discussed on FoodStuff
"Strange way on but okay let's talk about tofu and nutrition of as any said at the top of the show tofu is relatively high in protein it's kind of midrange in fats and low in carbohydrates that means that it's filling and also that it won't uh speicher crash your blood sugar good times they're the fats that are in tow few a pretty good for you there mostly monounsaturated fatty acids aka the stuff that's been shown to lower vat ldl cholesterol levels in your body and tofu itself contains no cholesterol it's a fairly high quality protein especially for not being an animal product which means that it it contains relatively high amounts of all of the essential amino acids which are the ones that our bodies cannot produce and thus that we have to get from foods it is always best especially when designing a vegetarian diet to eat a variety of different foods that you can intake all the stuff that your body needs over the course of a day everything the body needs yes it unfortunately we don't have that that slurry of of matrix stuff so inflation lately or unfortunate debate to be had either way i guess you could just drinking a whole lot of soil int moves i don't actually recommends that either sorry soy lent you're not it's not terrible it's it's quite find guess eats them eats eats indifferent vegetables is what i'm saying yes tofu still but good source nutrients that any was saying and a speak speaking of the nutrients and tofu it's best to buy it and opaque orsini okay containers because as with dairy products exposure to light will degrade some of took whose nutrients such as omega3 fatty acids.
"ldl" Discussed on Ben Greenfield Fitness
"Due to what appears to be called the glycogen sides in green tea without the change in the coenzyme q ten so in terms of you know i i do not think in any way that ldl as bad i try to keep my own cholesterol elevated above two hundred my ldl cholesterol very high but at the same time when it comes to small particles or oxidized cholesterol that's what i'm careful with and it appears that green tea does a very good job of decreasing some of those deleterious blood lipids so that's that's one interesting thing about it another thing is that it appears to assist with post exercise glycogen recent thisiis meaning that after a workout or let's say i'm working out in the morning and i want to store up my carbohydrate levels after that work out more quickly from whatever i might eat for breakfast and i also want to oxidized fat more efficiently because it mobilizes fatty acid there appears to be a beneficial effect from that as well and i'm not eating a lot of carbohydrates in the morning along with my green tea for that glycogen said the sis but remember your body can synthesized glycogen from the glycerine backbone of fats and it can also the process called gluconeogenesis synthesize glycogen from the glucose derive from proteins and it appears that green tea might actually help with all of these type of a type of mechanisms for giving your liver and your muscle extra like agenda burns say later on for hard work out so.
"ldl" Discussed on WAFS Biz 1190
"Cholesterol and ldl i used to say lousy cholesterol but now i say 'almost lousy cholesterol nor will look into that so we at least to learn that we needed to look at these subfraction nations we needed to look at these two other com components and these two other components have exactly opposite affects in the body hdl cholesterol goes out into your body grabs cholesterol brings it back to the liver and breaks it down ldl cholesterol almost does a lousy thing almost puts coalesce drawn to plaques but not quite we'll discuss that but it's it it it's getting closer so we now know okay you gotta tease these two out and they look different they act different the body this gives us more specificity but the story didn't and there what we then bound is that not all the colors as bad as as each other they're just because you're ldl does that mean you're all creative equal and just because you're hdl doesn't mean that you're all created equal of science progresses technology improves and now we can look inside that ldl and the hd out and we can do what's called sub fractionation so just think about a pie or cutting the smaller peace says the same is true of your ldl hdl now we can look at it more closely we can break it down even more and those pieces of lipids with in ldl or hdl also tell us something you can measure how buoyant the particles are so we now we know it's not even looking at el biar hdl but it's looking at particle size and how buoyant they are because that is actually what determines the activity in the body okay where almost lehrer we've almost trace the history of cholesterol and and why we're looking at these different components and so one last piece of the history lesson is restarted with cholesterol we learned how to break it town we made a couple of categories we learn how to look even more specifically at that look at the particles within the particles now the the real plaque former the real plaque former is not ldl what i said what i say is the almost lousy cholesterol the real platform former is oxidized ldl why is this important well it's important because ldl.
"ldl" Discussed on The Skeptics' Guide to the Universe
"Mmm who grams of polyunsaturated term graham's it's so high in these dangerous fat it's just the one of the most dense things you could possibly eat and that does translate to these ldls these basically these lipids or lipid what are they called liberal proteins in your blood stream it you're just increasing the level of them that you would find their so here's a little bit more directly from the study because they looked at a lot of new trials and pointed out a lot of pretty interesting things so there was this study between coconut oil and vegetable oils high in monaco on saturated fats and polyunsaturated fats let's say they looked at individuals who are eating coconut i'll verses individuals who had the same intake as canola oil so they also looked at the effects of of butter and saf lower oil butter and coconut oil raised ldl cholesterol compared with south flour oil butter did it more than coconut oil because note will still raised it significantly and those who took vegetable oils high in monterey unsaturated fast versus those who coconut oil did not see an increase in their ldl cholesterol and remember we're talking about ldl ldl ldl because you may have read some more recent reports those of you follow the kind of nutrition literature showing that it it's not a really good idea any more to link hdl to cardiovascular disease if you specifically just look at hdl on its own it's not a very good predictor of much.