19 Burst results for "Jean Brodie"
"jean brodie" Discussed on Anna Faris Is Unqualified
"Viagra was developed originally for old men. Who wasn't made for young men. 35-year-old-man is a vital male sexual away so something is going on on his right. Actually the medication he takes depression. It's going to impact his sexual drive because they just do. They have side effects. I'm going to be honest like when your personal usership be like you. Wolf new thing. You know like medicine cabinet. And so i was like oh take biogra- and my first reaction was like. Oh it's because he he's on antidepressants. Like what makes total sense and so when he was telling me that this is this is the reason why i you know i take because and i thought it going to be because i can't get hard. Say hard. whatever because of the medication. I'm on and he didn't say that it was not the answer that i expected. You know. i thought about what he was going to say. It could very well be a combination. You'll maybe the maybe. The medication is exacerbating some issues. That maybe he had. But i wouldn't discount. I mean like some of those medications are pretty powerful. I'm surprised that he's he's not taking that into account as that's what i brought it up to like also you're on antidepressants. So don't put this on here so it's like excuse me like obviously affecting you. Emily you wrote in your email and you've told us that you have brought it up. It's not like you haven't been communicating these concerns to your partner. But i wonder how you can communicate in a more effective way. I guess that wouldn't upset him or lead to places of defensiveness in our earlier conversations. Emily dr alex talks about how women are like in their sexual prime in like thirty five to forty right. The prime of miss. Jean brodie in baby he would act like all the time like horny. That's right and so it's hurtful when you're like Like i'm like oh man. I thought we were gonna be like bone and all the time you know. Because that's what we were doing it. I you know he's a wonderful man. It's like i don't want to make him feel shame that or there. There's something wrong with him. But i also want him to like take a bigger responsibility. Yeah if you add a little bit of that information in it makes it about your needs as opposed to his inadequacy. When i think telling him. How happy sex with him makes you feel. I did say that. Even if we don't have i would love it. If you were just at least tell me like you fucking gun today like you want. When you're like you know you look beautiful. Like i still need these kind of like words me. I'm not physically getting it like. Please tell me that you do want me. You do desire me. Maybe you can't always like physically do that. But and he has been trying to do that..
"jean brodie" Discussed on WNYC 93.9 FM
"At six PM so now let's get started after Carol Kane is known for her scene stealing performances in both starring and supporting roles on screen and on stage she got her start in the theater world and the stage production of the prime of miss Jean Brodie her work in film earned her an Oscar nomination and a place in pop culture history when she repeated Humber deck in the princess bride and of course on TV came one two enemies and a place in every viewer's heart playing simple gratis on taxi no reason we shouldn't been portraying a very different kind of New Yorker one we all kind of recognize that classic old school eccentric you only find here it's in the Netflix series unbreakable Kimmy Schmidt came plays Lillian Christopher coast brokers in right can you alert and a staunch opponent of gentrification it goes like that open manhole so we can start carrying around an old or to keep from falling in kids this can only mean one thing gentrification is common I mean pretty soon will be at no not because some yuppie thing to building has good bones we can't let's confine my husband's bones the fourth season of the show aired back in twenty eighteen the creators Tina fey and Robert Carlock found a way to get the gang back together one last time for the new unbreakable Kimmy Schmidt movie Kimmy versus the Reverend it's an interactive special that lets viewers make decisions that affect the final outcome for Kimmy and company the original cast returns Ellie Kemper Tituss Burgess Jane Krakowski and Jon Hamm the joined by special newcomer Daniel Radcliffe we're so happy to have Carole King here today Carol welcome to all of it thank you have you had to be here with you so you said before writing is the most important thing if the thing you look for when you're choosing a project what was it about the writing for Kimmy Schmidt that compelled you to get on board well you know it's Tina fey and her partner Robert Carlock who wrote at thirty rock and you know they're just so brilliant and that's what compelled me I I I knew that I would be in great creative hands and I was not remotely disappointed I was thrilled and it just you know I got really spoiled early on and that the first television I was involved in was taxi you know Kim Bergson add one Bergen stand Danielson they were very young and it's hard to it's hard to say yes to something that less good and in this case I I I was able to just say a whole hearted yes and feel supported and then of course the cast is spectacular okay and just so much fun and and now we have this little cherry on the cake thing happened which is set as we we did we did get canceled by Netflix but then they I know that Keenan Robert felt that they had a million more stories to tell and Netflix gave us this interactive special where they eat you know you mentioned a little bit about how it works but the viewer gets to like every I'd say maybe three or four minutes as the special goes along every three or four minutes the viewer gets two or three different choices as to where they want the character to go and you pick one and it just completely changes the trajectory of each character and story and then on the fabulous thing unlike real life is that you get to do over its many coupons that give you think oh I I I wanted to see what other did well you get to do it you just get to keep doing it so that's very that's kind of fun I would as an actor it's funny when you watch it because you have to take these long pauses well that and kind of stare into the camera while the viewer has to make a choice between one or two things what was the direction you were given hello we don't usually at I mean somebody usually comes in and says something stupid stories something when I say stupid I mean hilariously stupid and and you know you know it's it's very much in an old comedy style so he you know you don't have to think of anything profound you just have to wait it's just it's really turn up and then I have to say because I am on this certain age and so therefore I can tip computer illiterate and I thought oh my god this thing is going to come out and I am not going to be able to watch it because I'm not going to understand how to you know interact with the computer and make choices they have made it so simple because they're just like there's like little boxes at the bottom and you just take your little hand thing and click on one and that's it okay even I could do it so don't be intimidated no it's really fun it's for aids it is it's very fun to think about where the story lines are going you don't think I haven't seen all of them by the way ET you know I mean you you you can just watch it watch it watch and none of them Lillian is she's just as great character she's just this heightened version I think everybody knows someone a little bit like Lillian what what did you connect with in this character as a New Yorker well I zero what I think I remember was the first time that I got on the subway used to be a get on the subway on the Upper West Side and you go all the way downtown right and when you got off the subway you'd be getting off in another world you know the neighborhood what would look like a completely different world than where you got on that play and and I'll never forget the first time I got on a train on the Upper West Side and get that up and so and it was like the same you know pharmacy in the same you know all the same stories in the thing and I thought how can this be that it's gone yeah you know the new York of individualized neighborhoods and passions is is gone and of course as you know tragically I guess it's going more and more and more each each day although now I never will national world who knows what's gonna happen maybe it'll come back I don't know but and I think that that you know Lillian it has that experience in a heightened passionate way anyway what she feels like she could do something about it like she's not going to take it lying down if he doesn't take anything lying and I'm I think for me the great thing about getting have placed her is that she's so different than I am and that I am constantly concerned about what other people would change in a lot of people get mad at me if I face section said can I better shut my mouth and I am really anxious that's not existent for her she she just whatever comes into your head Adam out and she could care less what you think about it you know that's really a fun thing to get the plan I certainly have met at New York games that share that in common with billion and it's really fun and and of course like I say when I do open my mouth and say something it's just a great writing you know and yeah and my my guess Carol Kane we're talking about unbreakable Kimmy Schmidt Kimmy verses the reverent Luhan had Lillian has an important role I thinking can be life she really plays a part in the education of Kimmy Schmidt what is what is lonely and want to make sure Camino is when can he comes out of a bunker for people who don't know that that carried the main character had been in a kidnapped and put in a bunker and she comes out and and wants to make a life for herself in New York City I think sort of building on what I was just talking about the notion that she should speak her mind as she feels that and think that she should be brave and speaker mine because she is valuable and to see if she certainly was learning the opposite lesson in a bunker wish we wish she had been you know taught to be subservient and not speak out against this sort of religious leader the Reverend played by Jon Hamm and so I think my role it was sort of to elle ever helped arrange that submissive nature of hers and and maker the hope that she could feel free to enjoy her life and that that means being herself and being proud of it that's what I think the pace the comedy on the show is so fast it's just like a waterfall of jokes and jokes and jokes oh my god I I can never all of that in it at the table reads that we would have what we we know how the meaning of half of what we were saying I can't really think about it sometimes I had no idea what I was saying until six after the episode we shot and then I would say that the writers who what when I said and I would have got like you had an idea what I thought I meant it would have been completely wrong but that doesn't matter once you make a choice that's all you need but it is it's so as you say it's so fast their mind so fast they're they're so smart and then and then this one it's true in spades and the specialized don't you yeah I mean it's it's you have to keep up I mean this is the kind of show even though it's sort of fun and and at times frothy enjoyable you have to pay attention yes the jokes keep coming so fast yeah and and and you can see it again and again and find new stuff I mean that's that's that was true when it was the theories and that's true with this special moment and I do have to say one nice thing for Larry and in this special is that she has a lot to do with prince Frederick played by Daniel Radcliffe I'm gonna give it away you get you get to kiss him well now is version one version about and I'm like at my age to get to be forced to kiss Daniel Radcliffe you know sometimes life is very good don't you think I mean it's so much fun I got to sing damn do some sexy dancing and oh my god I had so much and then I get to be home which is really a bonus for me I get to be his British nanny Fiona and I've never gotten to may be kind of a very fine Mary Poppins type of British man they have never gotten to do that nor would I have ever imagined I get to do that in my life so thanks Tina and wrap it you mentioned working with with Tina and Robert have wanted joy that was to work with them to creatively as professionals I mean in your career you've worked with huge names mainly met Mike Nichols and Alan is there someone in a modern day writer director that you think I'd really like to work with this person well there's a lot of them but.
"jean brodie" Discussed on BrainStuff
"Look to bring stuff a production of iheartradio brain lauren. Bo-bottle here during party conversation or at a Trivia night you may have heard the fun little fact that humans and bananas share fifty or even sixty percent of the same DNA. There seems to be a lot of differences though between a person and a piece of yellow fruit starting with the fact that one is an animal and the other is a plant but actually there is some truth to that startling statistic but it's not the whole truth. This urban legend of sorts likely originated from a program run by the National Human Genome Research Institute. Back in two thousand thirteen although similar data may have been run elsewhere genetics expert. Dr Laurence Brodie and his colleagues generated some banana human information to be included as part of an Educational Smithsonian Museum of Natural History video called the animated genome that video noted that DNA between a human and a banana is forty one percent similar so in order to find out how this similarity was determined. We talked with Dr Brody himself. He explained that. I it's important to understand the difference between DNA and protein products. You can think of DNA as the blueprint of a house and protein products is the actual house. Because all the information is in there Then think of human. Dna is the blueprint for a ranch home and banana. Dna is that of a condo in each house. A bunch of things are similar. The plumbing bathrooms kitchen and products are both quite different. That's how it works with humans versus just about everything else from bananas to chimpanzees. The second thing to keep in mind is that genes which are the regions of DNA that code for proteins. Only make up about two percent of your DNA in order to compare humans and bananas scientists. I looked at the sequences of genes in a typical banana. Gino Brody said we then used these DNA sequences to predict the amino acid sequence of all the proteins. That would be made from those genes. We then did the same process for all human genes. All of the protein sequences were placed in a file next. Scientists compare the protein sequence from each gene to every human. Jean Brodie said the program compares. How similar the sequence of the banana genes are to each human. Gene Program? Kept any matches that were more similar than one would expect by chance. The program continued doing this gene by gene all told more than four million comparisons were done resulting in about seven thousand best hits between the two genomes then the percent similarity score for each of those hits was averaged. Brady said this gave us the result of about forty percent. This is the average similarity between proteins. Gene products not genes gene products or proteins are the biochemical material resulting from Jean becoming functional. Brody continued of course there are many many genes in our genome do not have a recognizable counterpart in the banana genome and vice versa. In case that's a bit difficult to chew and swallow. Let's break it down. Essentially they took all of the banana jeans and compared them one at a time to human genes from that they called a degree of similarity if the banana had the gene but the human didn't that didn't get counted and about sixty percent of our genes have a recognizable counterpart in the banana. Genome Brady explained of those sixty percent. The proteins encoded by them are roughly forty percent identical when we compare the amino acid sequence of the human protein to its equivalent in the banana. It may seem shocking that so many genes so many of the proteins that they create are similar in to such vastly different beings as a person a banana. But when you think about it. It's not that shocking Birdie explained if you think about what we do for living. And what banana does. There's a lot of things we do. The same way like consuming oxygen a lot of those genes are just fundamental to life so when people repeat the percentages being a similarity of DNA. Actually what the research looked at was the similarity of gene products. Brody reassured US. It's a pretty minor mistake. The kernel that you would take home is that we have something in common with a banana and a potato in the pine tree. That part is true. The fine points about the gene products or the DNA. It's easy to see how that would get translated incorrectly. So a scientist looked at the DNA sequence of a banana and compared it with the DNA of a human it would not align we also spoke by email with Mike Francis a PhD student in Bioinformatics at the University of Georgia. He explained you share fifty percent of your DNA with each of your parents but with bananas we share about fifty percent of our genes as we said earlier genes make up just two percent of your DNA. So what's the other ninety eight percent made up of well? Eight percent of the rest of your DNA regulates as to whether a gene should be turned on or off. The other ninety percent appears to have unknown functions or functions that have been lost through evolution. Francis said these unknown sections of DNA used commonly be called junk DNA because it was thought to do nothing. I hesitate to use the phrase junk DNA because each year. It seems we realized more of this junk is actually functional. Humans don't just share. A high percentage of protein coding genes with bananas. We also share eighty five percent of those genes with a mouse and we share sixty one percent of disease causing genes with fruit fly. Brody said the remarkable thing is that despite being very far apart in evolutionary time we can still find a common signature in the genome of a common ancestor. These are preserved because the genome of an organism that lived billions of years ago contained genes. That helped cells live and reproduce those same jeans are preserved in US and plants Francis added the humans likely share about one percent of their DNA with other fruits as well he said this is because all life that exists earth has evolved from a single cell that originated about one point six billion years ago in a sense. We're all relatives. Today's episode was written by aaliyah. Hoyt and produced by Tyler. Klag brain stuff is a production of iheartradio's has to works from on this and lots of other topics that are different but do similar things visit our home. Planet HAS WORKS DOT Com. And for more podcast. My heart you can visit iheartradio APP apple podcasts. Or wherever you listen to your favorite shows..
"jean brodie" Discussed on WNYC 93.9 FM
"Billionaire has after investing hundreds of millions of dollars in a media campaign blitz across this country the former mayor of New York City Michael Bloomberg will be on stage for the first time with his democratic rivals the billionaire has already drawn the attention and I are of many of his opponents even though he's not actually competing in the Nevada caucuses this weekend he's running a non traditional campaign that bypasses the first floor early states former Vermont senator Bernie Sanders who has often ridiculed billionaires has been particularly critical of Bloomberg in recent days and not just around issues of income inequality but also for the former mayor's record around a controversial policy called stop and frisk that disproportionately targeted minorities so it will be telling to see how much these two candidates tangle tonight a small college NPR news the novel coronavirus outbreak has now infected more than seventy five thousand people most of them in China and cost hundreds of lives research labs around the world are trying to come up with therapies for the new virus and here's Joe Palca reports there are two basic approaches researchers are taking one approach involves finding a drug that will disrupt one of the biological steps of virus needs to infect cells this could be blocking a critical enzyme or interfering with the virus's ability to make copies of itself the second approach involves making drugs that act like the human immune system does these so called monoclonal antibodies can be made from the immune cells of patients who had covert nineteen and got better or they it can be made using mice that have been given what amounts to a human immune system scientists are reasonably confident one of these approaches will be successful how soon is another matter Joe Palca NPR news people across Afghanistan are waiting to see if an agreement between the US and the Taliban requiring a reduction in violence takes the pact is going into effect against a backdrop of political strife out of Kabul and to add to the tension and pierced the head deed says now there's been an explosion the blast was a rocket that landed near the airport it caused no injuries but shook nerves it came on a day would rivals of the president of stuff funny announced a parallel government and threatened Election Commission staff the staff at an ounce of any one presidential elections with the tiny majority the ballot was held five months ago but the announcement what's told to recount fights of Khan's also waiting for the Taliban to scale back their attacks which will likely lead to the insurgents signing a deal with the United States on American troop withdrawal this is NPR for W. NYC in New York I'm Jennifer the nasco jurors are now in their second day of deliberations in a re trial that could send disgraced movie producer Harvey Weinstein to prison for the rest of his life the panel of seven men and five women had lots of questions as a way the charges jurors asked to examine emails between winds dean and film production assistant meaning Haley one teen faces five felony sex crime charges his lawyers contend the acts were consensual new research shows revenue for businesses in black neighborhoods grows more slowly than those in other areas even if they have positive customer reviews the Brookings Institution looked at revenues and run yelp ratings and controlled for other factors like in areas walkability Andre Perry says the study suggests racial stigma is the reason for the drop off it's clear that race is a significant factor in preventing people from going to businesses to get the better sandwich to get the position simply because of their neighborhood there in New York City revenue for businesses in black neighborhoods grew by seven percent between twenty sixteen to twenty nineteen compared to over eight percent for other areas of the city hi four time Tony Award winning actress zero Caldwell has died colder rose to brought I started in nineteen sixty eight as an eccentric school teacher in the prime of miss Jean Brodie she was famous for playing larger than life characters like the aging opera star Maria Callas and Terrence McNally's master class her centrally white had said she died at home in Westchester county of complications from Parkinson's she was eighty six pleasant today currently forty four degrees and sunny in Central Park this afternoon we'll.
"jean brodie" Discussed on NPR News Now
"Able to do that because he's rich rich friends if he's going to have good ideas and he wants to bring good ideas little table totally but at this point in the game. I'm not really paying close attention to that. Being said Democratic voters were quick to say they would support Bloomberg if he did received the nomination for NPR news. I'm Bob over and Reno. China has revoked the press credentials of Three Wall Street Journal reporters based in Beijing. F- here's Emily Chang. Reports the move comes the day after the. Us State Department designated five Chinese state media outlets as foreign government missions. China's Foreign Ministry is at the three reporters were expelled in retaliation for an op. Ed The outlet published from an author based in the US China has effectively expelled at least six other journalists since two thousand thirteen by refusing to renew their press credentials but outright canceling a valid credential is rare in cancelling multiple credentials from the same outlet is unprecedented NPR's. Emily Chang deliberations in the Harvey Weinstein Sexual Assault Trial Continue in Manhattan courtroom today. The former movie producer is charged with raping a woman in in Manhattan Hotel Room in two thousand thirteen and forcing another woman to perform a sex act in twenty two thousand six. He says any sexual contact was consensual. This is NPR. An additional seventy nine people on board the Diamond Princess cruise ship docked off the coast of Japan have tested positive for the cove in nineteen virus also called the corona virus under the Americans on board. That ship were flown to the US. On a chartered plane including fourteen people. Who TESTED POSITIVE. For the virus. Meanwhile new cases in China appear to be slowing four time. Tony Award winning actress Zoe Caldwell. I'd Sunday in her home in pound Ridge New York of complications from Parkinson's disease she was eighty six. All she appeared on television and in Film Has Jeff London reports. She was up powerful presence on the stage born in Melbourne Australia. Zo Caldwell made her professional debut in Peter Pan at the age of nine in her twenties she performed in Repertory Theatre in Australia then moved to England where she became a member of the Royal Shakespeare Company. She also performed at Canada's Stratford Shakespeare Festival and the Guthrie Theater in Minneapolis. Before settling in New York Caldwell won her first Tony in slapstick tragedy. A pair of Tennessee Williams one actors which lasted only a week but she won her three other tonys for big hits the prime of Miss Jean Brodie media and masterclass for NPR news. I'm Jeff London. In New York World Financial Markets Asian markets were higher by the close. The Nikkei the main market in Japan up nearly nine tenths of a percent. The hang sang nearly a half percent. Us futures contracts are trading positive. I'm gene herbst. Npr News in Washington..
"jean brodie" Discussed on BrainStuff
"Vogel bomb here during Party conversation or a Trivia night you may have heard the fun little fact that humans and Bananas Sheriff Fifty or even sixty percent of the same DNA there it seems to be a lot of differences though between a person and a piece of yellow fruit starting with the fact that one is an animal and the other is a plant but actually there is some truth to that startling statistic but it's not the whole truth. This urban legend of sorts likely originated from a program run by the National Human Genome Research Institute back in two thousand thirteen. Although similar similar data may have been run elsewhere genetics expert. Dr Laurence Brodie at his colleagues generated some banana human information to be included as part of an Educational National Smithsonian Museum of Natural History video called the animated genome that video noted that DNA between a human and a banana is forty one percent similar so in order to find out how this similarity was determined. We talked with Dr Brody himself. He explained that. I it's important to understand the difference. Prince between DNA and protein products. You can think of DNA as the blueprint of a house and protein products the actual house because all of the information is in there Then think of human DNA is the blueprint for a ranch home and banana. DNA is that of a condo in each house. A bunch of things are similar. The plumbing bathrooms kitchen and products are both quite different. That's how it works with humans versus just about everything else from bananas to chimpanzees. The second thing to keep in mind is that genes which are the regions of DNA that code for these proteins. Only make up about two percent of your DNA in order to compare humans and bananas scientists. I looked at the sequences of jeans and a typical banana. Genome Brody said we then used these DNA sequences to predict the amino acid said sequence of all the proteins that would be made from those genes. We then did the same process for all human genes. All of the protein sequences were placed in a file file next. The scientists compared the protein sequence from each banana gene to every human. Jean Brodie said the program compares. How similar the sequence of the banana genes are to each human? Gene Program. Kept any matches that were more similar than one would expect by chance. The program continued doing this gene by gene seen all told more than four million comparisons were done resulting in about seven thousand best hits between the two genomes then the percent similarity score score for each of those hits was averaged Brady said this gave us the result of about forty percent this is the average similarity between proteins gene products. Not What genes gene products or proteins are the biochemical material resulting from Jean becoming functional. Brody continued of course there are many many genes in our genome that do not have a recognizable counterpart in the banana genome. Ns Versa in case. That's a bit difficult to chew and swallow. Let's let's break it down. Essentially they took all of the banana jeans and compared them one at a time to human genes from that they called a degree of similarity. If the banana had the gene. But the human didn't that didn't get counted and about sixty percents jeans have a recognizable counterpart in the Banana Genome Brady explained and of those sixty percent. The proteins encoded by them are roughly forty percent identical when we compare the amino acid sequence of the human protein twins equivalent in the banana. Uh it may seem shocking that so many genes and so many of the proteins that they create are similar in to such vastly different beings as a person in a banana. But when you think about it. It's not that shocking. Brody explained if you think about what we do for living and what a banana does. There's a lot of things we do. The same way. Like consuming oxygen a lot of those genes are just fundamental to life so when people repeat the percentages being a similarity of DNA. Actually actually what the research looked at was the similarity of gene products. Brody reassured US. It's a pretty minor mistake. The kernel that you would take home is that we have something in common with a banana and a potato and the pine tree that part is true. The fine points about the gene products or the DNA is easy to see how that would get translated incorrectly so the scientists looked at the DNA sequence of a banana and compared it with the DNA of human it would not align. We also spoke by email with Mike Francis a PhD student in Bioinformatics at the University of Georgia. He explained you share fifty percent of your DNA with each of your parents but with bananas as we share about fifty percent of our genes as we said earlier genes make up just two percent of your DNA. So what's the other ninety eight percent made up of well. Eight percent of the rest of your DNA regulates genes as to whether a gene should be turned on or off other ninety percent appears to have unknown functions or functions that have been lost through evolution. Francis said these unknown sections of DNA used to commonly called junk DNA because it was thought to do nothing I hesitate to use the phrase junkie because each year. It seems we realize more of this junk is actually functional. Humans don't just share a high percentage of protein protein encoding genes with bananas. We also share eighty five percent of those genes with a mouse and we share sixty one percent of disease causing genes with a fruit fly. Brody Brody said the remarkable thing is that despite being very far apart in evolutionary time we can still find a common signature in the genome of a common ancestor. These are preserved served because the genome of an organism that lived billions of years ago contained genes. That helped cells live and reproduce. Those same jeans are preserved in US and plants Francis added that humans likely share about one percent of their DNA with other as well. He said this is because all life that exists on earth has evolved from a single cell fell originated about one point. Six billion years ago in a sense. We're all relatives in. Today's episode was written by Hoyt produced by Tyler claim. Brain stuff is the production of iheartradio's has to work for more on this month's of other topics that are different but do similar things visit our home planet. How stuff works DOT COM and for more podcast in my heart radio you can visit? I heart radio APP apple podcasts. Or wherever you listen to your favorite shows..
Do Humans and Bananas Really Share Half Their DNA?
"During Party conversation or a Trivia night you may have heard the fun little fact that humans and Bananas Sheriff Fifty or even sixty percent of the same DNA there it seems to be a lot of differences though between a person and a piece of yellow fruit starting with the fact that one is an animal and the other is a plant but actually there is some truth to that startling statistic but it's not the whole truth. This urban legend of sorts likely originated from a program run by the National Human Genome Research Institute back in two thousand thirteen. Although similar similar data may have been run elsewhere genetics expert. Dr Laurence Brodie at his colleagues generated some banana human information to be included as part of an Educational National Smithsonian Museum of Natural History video called the animated genome that video noted that DNA between a human and a banana is forty one percent similar so in order to find out how this similarity was determined. We talked with Dr Brody himself. He explained that. I it's important to understand the difference. Prince between DNA and protein products. You can think of DNA as the blueprint of a house and protein products the actual house because all of the information is in there Then think of human DNA is the blueprint for a ranch home and banana. DNA is that of a condo in each house. A bunch of things are similar. The plumbing bathrooms kitchen and products are both quite different. That's how it works with humans versus just about everything else from bananas to chimpanzees. The second thing to keep in mind is that genes which are the regions of DNA that code for these proteins. Only make up about two percent of your DNA in order to compare humans and bananas scientists. I looked at the sequences of jeans and a typical banana. Genome Brody said we then used these DNA sequences to predict the amino acid said sequence of all the proteins that would be made from those genes. We then did the same process for all human genes. All of the protein sequences were placed in a file file next. The scientists compared the protein sequence from each banana gene to every human. Jean Brodie said the program compares. How similar the sequence of the banana genes are to each human? Gene Program. Kept any matches that were more similar than one would expect by chance. The program continued doing this gene by gene seen all told more than four million comparisons were done resulting in about seven thousand best hits between the two genomes then the percent similarity score score for each of those hits was averaged Brady said this gave us the result of about forty percent this is the average similarity between proteins gene products. Not What genes gene products or proteins are the biochemical material resulting from Jean becoming functional. Brody continued of course there are many many genes in our genome that do not have a recognizable counterpart in the banana genome. Ns Versa in case. That's a bit difficult to chew and swallow. Let's let's break it down. Essentially they took all of the banana jeans and compared them one at a time to human genes from that they called a degree of similarity. If the banana had the gene. But the human didn't that didn't get counted and about sixty percents jeans have a recognizable counterpart in the Banana Genome Brady explained and of those sixty percent. The proteins encoded by them are roughly forty percent identical when we compare the amino acid sequence of the human protein twins equivalent in the banana. Uh it may seem shocking that so many genes and so many of the proteins that they create are similar in to such vastly different beings as a person in a banana. But when you think about it. It's not that shocking. Brody explained if you think about what we do for living and what a banana does. There's a lot of things we do. The same way. Like consuming oxygen a lot of those genes are just fundamental to life so when people repeat the percentages being a similarity of DNA. Actually actually what the research looked at was the similarity of gene products. Brody reassured US. It's a pretty minor mistake. The kernel that you would take home is that we have something in common with a banana and a potato and the pine tree that part is true. The fine points about the gene products or the DNA is easy to see how that would get translated incorrectly so the scientists looked at the DNA sequence of a banana and compared it with the DNA of human it would not align. We also spoke by email with Mike Francis a PhD student in Bioinformatics at the University of Georgia. He explained you share fifty percent of your DNA with each of your parents but with bananas as we share about fifty percent of our genes as we said earlier genes make up just two percent of your DNA. So what's the other ninety eight percent made up of well. Eight percent of the rest of your DNA regulates genes as to whether a gene should be turned on or off other ninety percent appears to have unknown functions or functions that have been lost through evolution. Francis said these unknown sections of DNA used to commonly called junk DNA because it was thought to do nothing I hesitate to use the phrase junkie because each year. It seems we realize more of this junk is actually functional. Humans don't just share a high percentage of protein protein encoding genes with bananas. We also share eighty five percent of those genes with a mouse and we share sixty one percent of disease causing genes with a fruit fly. Brody Brody said the remarkable thing is that despite being very far apart in evolutionary time we can still find a common signature in the genome of a common ancestor. These are preserved served because the genome of an organism that lived billions of years ago contained genes. That helped cells live and reproduce. Those same jeans are preserved in US and plants Francis added that humans likely share about one percent of their DNA with other as well. He said this is because all life that exists on earth has evolved from a single cell fell originated about one point. Six billion years ago in a sense. We're all relatives
"jean brodie" Discussed on Trivia With Budds
"Yes. Crack could be it's the borough aka the Weasley home one start out at his uncle aunt uncles, and he goes away. Yeah, here's the third one Dame Maggie Smith who plays professor mcgonagall in the Harry Potter films has won two Oscars name, one of the films for which she has won. This has nothing to do with Potter. It's true. And also never heard of these movies, then I have no idea. The prime of miss Jean Brodie, actress nineteen seventy California, suite best supporting actress nine hundred seventy nine two cards shit unknown those all right in the film, Harry Potter, and the source stone. What is the password, the fat lady demands when the Griffin door students are taken to their common room for the first time me me me me, me or something like that? Kaput drew krona's. What you call me. Sure. How bizarre. All right. Next one. The cat in the opening scene of Harry Potter, and the Sorcerer's Stone turns into whom that's gotta be mcgahn ago. Yeah, that's correct. Nice. We learned that earlier we did. In the film, Harry Potter, and the chamber of secrets who plays Tom riddle? You don't know this. L ROY Flynn the second. Christian colson. That's the thing. Two cards left each in the film, Harry Potter, and the Sorcerer's Stone, which student is the first to fly on a broomstick during the flying lesson her mining. No, no, no. I take it back as the scared kid is it novel? It is Neville. Nice job, four points for you in the film, Harry Potter, and the chamber of secrets Dumbledore tells Harry, the tears of Phoenix have, what magical quality tiers of Phoenix. Renewal sure that kind of counts, it's healing power. You have five points and Ralph fines plays. The evil Lord voldemort in Harry Potter and the goblet of fire in nineteen Ninety-three film, that he play another, incredibly evil character named Ayman go with. Can figure this out ninety three film incredibly evil? Aim on Amazon Goethe GIO h. I've actually never seen this movie, have I seen it? I think so. Probably. Is it a vampire movie? No. Historical movie. Is it all? Medes Schindler's List. Right. You've got five points. I got one card left about ten questions. Here I have three cards left, so you gave me six cards. So put one of those men, all right? Here we go. All right in the film, Harry Potter? The source stone. What does Hagrid have on his hands? When Harry Ron and her mind he go to his hut to ask about the Sorcerer's Stone. What does he have his hands? Correct. So very weird question. Like Honey, or something of admits duh? That's a trivia question. That's what I said. I have nothing to do with anything. What was the actor thinking about when he was standing there dogs next question? Stupid in what Harry Potter film, does Harry, I speak parcel tongue without realizing it. Goblet of fire. Slow stone. All right, next restaurant in the film, Harry Potter and the chamber of secrets a portrait of which wizard from another famous series of films, is on the wall and Dumbledore study. Gandalf cracked weird. I didn't know that rack that's a good little question. That is to use that in this Friday for the big show, is that like to pay Amish, the actor of the died. No, he didn't play that was Ian McKellen played off. Oh, who did he play wasn't? He also in Lord of the rings. He and McKellen wasn't it. Some whoever died, either the real Dumbledore the other one and they, they hired the replacement wasn't he. Interesting. Good. All right last card. So wait. What are you have? What's your score? Think guy have four and you have five you can't drive three. Maybe I've three and five you're beating me and all that matters. The film, Harry Potter and the chamber of secrets. What does her mind? Etele the other or Balaji students is fatal about the Mandrake. What is screen, it is? Yeah. It's cry. It says, so that counts job. Thanks. Okay. Next question. What? Yeah. I was gonna read my question. I didn't know redoing you pasta was waiting in the film, Harry Potter, and the Sorcerer's Stone, Dumbledore tells professor mcgonagall, he would trust Hagrid with what his life. Yes. Nice job seven points last question Dhabi has come to warn, you sir was one of the tag lines for which Harry Potter film. He has come to warn, you, sir. The fifth, one now second one chamber of secrets, or is that the first one. That's the second one I have no idea. I don't know the names of all of them all you ready your final questions. So what do I have seven I can't even beat you tie you five four, but I don't think I only have three. All right. You once we I've never won so excited. All right in the film, Harry Potter, and the goblet of fire who tells Harry, where to go to open the egg from the first task of the try was tournament. Roy Flynn next question Centric degree. I wasn't plays syndrich degree. This is just for your fun. Robert Pattinson, the world's new Batman. That'll be great. Yeah. Wait for him as Batman of you. You. Of course, I'm kidding. I've anything he should be voicing, like the new sonic, the hedgehog, did you hear they pushed that it's now got a romantic Valentine's. Airlie. Ooh. What a hot date that would be. Let's go see the hedgehog. Yeah. Two questions on in the film, Harry Potter and the prisoner of asks van where does aunt Marge say she would have sent Harry if he had been left on her doorstep. Where does aunt Marge say who's aunt Marge the mean we'll wasn't the baby left on her doorstep. No. I thought so. So that makes sense where she says, where does where would she have sent Harry if he'd been left on her doorstep? But he was left on her doorstep. If that's the end the orphanage. That's correct. Nice. I know stuff in the film, Harry Potter and the chamber of secrets who plays Cornelius fudge. I know that character, but I have no idea some old projector. Elroy flynn. Robert hardy, Robert hardy old rob hearty. Well, I think I had five points and you had seven so well done. Ooh. That was a good one and hurt my hand. A little bit. All right. Yeah. If you want, Ashley on your team for Harry Potter trivia this Friday. She's available. She'll helped me pass stuff out, and moderating things and cast cheaters slap the desk and stuff. Knuckles yell like unbridged. Yeah. If they cheat. That's a good idea. Yeah. I like that. Cool anything you want to promote wearing a wizard that beard. What do I get to wear? Let's the little hat, like unbridged. And she wear cute little hats, and all her weird teacups and stuff. Are all her plates with cats on them. I don't remember anything about her because she was mean she's crazy. Schwab pink all the time. I'm an easy address. I can't I know you've done. I know you wanna be a male character. But I need you to be happy. I've got plenty of hacker close. I could easily do that. All you should put Annabel and your shoulders and be a real tall Hagrid. That'd be funny. It'd be great could not carry NFL shoulders. All right. Thanks for doing this episode hunt. Anything else? Nope. Not expect patrol. No. There. It was a fun, little duel episode where my wife Ashley Starling buds, whooped my butt in some Harry Potter seen. It style trivia, and I now realize that most of those questions are from the movies because it is a movie based game seen it. So hopefully had fun playing along with those questions, and hopefully, you will remember forever that in that one scene, they go to the house, and he was wearing of admits good gravy. My dog covered his barked about it. And he heard him a second ago. Again, check out the website trivial buds dot com and comply with us this Friday at last name brewing. I'd love to see him tons of prizes. We got Ron Weasley and Dumbledore Barbie style dolls like in the package. Those will be great got socks ankle length. Full length Hogwarts different houses. Socks to give away got some shirts. Got some calendars. Got some artwork. Got some pin sets some key, some bookmarks. I mean, anything you can think of that they make. Harry potter? I've bought it over the last nine months, or so to prepare for this event. So it's going to be tons of fun, and I hope to see him and I'll make sure I record all the rounds that we do and put those out for fun. Harry Potter week. I don't know what a month or so after after it dies down. So get excited for that, if you want some more, Harry Potter trivia, just search Harry Potter trivia with buds on Google and click back through the feed, if you want to find some more episodes, we've done it, at least four or five times, I'm sure in the last two and a half years. So check it out. Thank you guys so much for listening. Thanks for telling a friend, about this show, and we'll see you tomorrow. For more trivia with buds. Cheers..
"jean brodie" Discussed on WFAN Sports Radio_FM
"Eight seven seven three three seven sixty six sixty six Sal licata back with you on the fan going to AM Tony page will be here. Then the Mets have such great confidence heading into the season, lots of talk of playoff so far first year Jean Brodie bandwagoning clearly bringing the competences group. They all love it Calloway talking about how they're on a mission to get to the playoffs. I have a tough time buying that. That will be the case. But I loved them saying it, I mean, it's great to save producer fleet your big fan, you confident in this group are you as confident as they seem to be themselves with this Mets group, not even close not even on the same planet as they are. I mean, they are talking a pretty big game. Right. I mean, van wagon and his competent is as you could possibly be in your one Callaway after last year, I'd be a little tentative and he's talking about playoffs. Now, I have a little bit of an issue with that. I love confidence. I love that attitude if they had if. They signed Bryce Harper. I'd be going up and down the streets of Manhattan, telling people, you know, the Mets are winning the division and win in the National League can go into the World Series this year. I love that bravado. If you have the ability to back it up, and I just don't think they have their roster right now. Well, that's the problem. And I was looking over the roster before they don't have. They added some solid depth. But they're not a loaded lineup. Sounds like the Phillies are gonna end up with Bryce Harper. That could be a problem because the Phillies have a terrific lineup that ballpark. He's dangerous. They don't have as good a pitching is a mess. But but the Mets don't have the depth in the pitching department that you need, and we're talking about eventually somebody's gonna get hurt or miss them starts, whether it's Syndergaard or Matt's. Whoever Wheeler somebody's gonna miss some stars who's gonna fill in Corey Oswald. So that's a little bit of a problem. The bullpens good we don't know how good it's going to be definitely better than it was a year ago. I just I don't know. I I do like what you're talking about producers leagues. And I do like the confidence. But I like quiet confidence. I don't need to hear them. Say come get us where the team to beat. You don't have to put that out there. You could do that amongst yourselves until you go out there and start to win because we've been down this road before talk talk talk talk talk, and they don't produce results. Same thing. Your boy Rex did for years. I'd be fine with that attitude to pretty much all I just want is a good team that I think can go out there and win. And then I don't really care what they're saying. Or not saying, I just I'm only okay with that kind of confidence if you can back it up. I mean, what's going to happen when they're thirty five and forty in a couple of months, and they still going to be talking saying where the team to beat come get us. That's just that's way too much for me before spring training. When I don't think there's anybody out there, even the most optimistic met fan thinks you're that good in that rock solid. And that's kind of what I was talking about earlier in the show to where you can talk good now, and you can have the positive, but you'll really learn about them and this club when they go through some adversity. So what is going to happen when? They hit a seven game losing streak or what's going to happen when they're thirty five and forty and people will start asking the question day. You guys are coughing. He said come get us your eight games back in the division. And you're at the ninety minute the all star break yet then want, and I think that's where you have a little bit of an issue with all the talking if they won ninety games last year. I have no problem with it. If they went out and made the big splash free agency, your point producer flakes. I'd have no problem with it. Or I'd have less of a problem with it. But they didn't do that. And they they they want seventy seven games they didn't sign the marquee free agents. And they're talking to big game. That's where it gets a little to the Yankees talk about that. You have the Yankees talked about how they're gonna go out there and dominate and come get us. They didn't do that. But they're loving Adria wise, and it's enough to the point where when you didn't go get that big free agent at your fan base for the most part has been clamoring for for years, and especially this year when there are two Marquis guys out there. And when you have inside your own Cy Young stud when you haven't done all. All that. It's even more of a turn off to your fan base. Say can you just shut up and do something for us? Just once because you never do that. You never actually give us anything on the field. And that is exactly why they need to sign. Jacob degrom. That is a goodwill move. First of all, it's a good baseball move. Forget about just the goodwill aspect of it. But that's a move. That will eliminate lots of problems. It will make the fan base at ease make them happy put them at ease degrom gets his money. He's happy. You have your ace locked up. It's one strong move. That's not even asking that much. But it's one move that can make a big difference and provide goodwill with the methane eight seven seven three three seven sixty six sixty six get back to the phones to chief is calling from cherry hill. What's up chief? Get sal. How about yourself? Right. Okay. I got two points about the giants might I point earlier caller, Nick foles. Yeah. I wouldn't say that mixed foles is a product of the system die. What say I don't wanna say. He's totally a product of his offensive line. But you gotta give it somewhat like we had to say somewhat a product of his offense, align I but quarterbacks all quarterbacks are going to be a product of their offensive line to a certain degree the issue with Folsom ease at anytime. He's not been Philadelphia. He's failed as a quarterback. I know it's two different things. One was with chip Kelly now Doug Peterson. But still there's gotta be something there that is making GAM had that success. He feels comfortable there, the coaches, whatever it may be although it's not just the offensive line. But yeah. If you come to the giants with their offensive line. I don't care who the quarterback is going to struggle. Listen, I I. It's totally often to see if a giant. He wouldn't be that wouldn't be that. Could you see he he told people all day? As a member of the eagles right after he had time yet. He spoke takes shots. And he doesn't get a little boost up the last game of the season. He took a night shot for the rich as a giant player quarterbacks. You I think with that offense allied. He'll be able to last six I don't think the past season. He's able to step in and Philadelphia play games and take those shots for you only have to play five sixteen as a giant sixteen games. There's no way that offense on why he's watching do you really want Nick foles over Eli manning. Anyway, I mean, I have a hard time with that transition. I don't mind going from ally to a young French potential franchise quarterback. I don't mind that transition. I do have a hard time going to Nick foles. I feel like it's not that much better than Eli manning. Even at this point. Honestly, listen, I don't think he's that much better. And with the prime of of a Barclay and OBI Jay if he doesn't next three four years. They don't win anything. So then you part of the players. Hey, you have to go. Finding quarterback if you get young quarterback right now, you even if they don't win for the next couple of years and Arkley and OBI J already four or five years into their career ready ready getting their tires you. We still have that young quarterback. And I wouldn't listen I would not trade Lovie J bringing in a young quarterback. How can you trade around telling you, look, look what's happening with same Donald talent around it? Yeah. But it's get talent. It's not about talent. Go junior's been there for a while. How many how many times the giants won with them? That's a great point. But for a young quarterback pieces around if he doesn't. But does he, but but chief does he need pieces like Odell Beckham junior with the attitude and talking about how he's gonna want the ball and Odell Beckham junior's been bad with they two time SuperBowl winning MVP. How you think he's gonna wear on a rookie quarterback? Who's going to be a rookie quarterback doesn't come into the league? What the greatest confidence in the world. You got to feel it out gonna deferred Odell Beckham junior. I don't think that's good situation. The same way where I want would not want Antonio Brown on the jets because a Sam darnold. I wouldn't want Odell Beckham junior around a rookie quarterback hoping you you don't think that for young quarterback that it's good to have a security blanket a guy who knows he gets the ball to. Yes. I do think that that's good. I don't think that that's all Dell Beckham junior. I think they'll Beckham junior thanks for the call chief. I think Odell Beckham junior's more of a problem. He's a great talent. But I'd rather have a good. Receiver with less of an ego less attention craving less or who who's more mature. There are a lot of things about Odell Beckham junior that turned me off and I can live with him. If on the patriots with Brady and Bella check, maybe. Plays out. You would think Antonio Brown would be. Able to be corralled or be made happy with Ben Rothlisberger at quarterback. But obviously he wasn't didn't buy into that. So how would Antonio Brown be around a young rookie quarterback? Kind of the same thing with Beckham junior feel like bands in Long Island. What's up? Yes, al. Yeah. What's up? Yeah. How you doing? I got one simple statement to make. And I hope you'll cut me off because I want you to tell me why I'm wrong. How is writes off of the biggest no-brainer in the world in the world. Since the beginning of agency allergy not the biggest no-brainer for the Yankees. What he would cost Yankees. Even if he bombed out the last nine years of his contract to put in between. Judge. And it would be a credible. You know? I mean, the guy walked hundred forty nine times last year he helped them out they'd help him out. It'd be a lock they have the greatest pitching staff in the world to shut those three down. Right. But here's the problem. You're gonna pay Bryce Harper over three hundred million dollars. I ain't gonna pay Aaron judge already paying. Let me ask you this. How much is hard to make for the Yankees if they win a world championship. That's what I want to know. Well, they might win a world championship without him. I mean, it's not like the Yankees. They have like eight chance. I mean, is it guaranteed that he's gonna win a championship with the Yankees? There's nothing guaranteed. I mean, three guys. Look look look at Boston's lineup..
"jean brodie" Discussed on Bullseye with Jesse Thorn
"You how many innings Hampel? Okay. So the first thing I was in was wizard of Oz. And I was a munchkin not to brag not to brag. But I mean, listen, it's my history. So then, you know, the munchkins have this thing. When Dorothy lands were they say, you know, don't go to the east for in the east, but don't go to the west for in the west. So you know, we were seven, and we just pointed our hands whatever direction. One don't go to the eastern, and he Jerry came storming down the aisle of the theater and explained to us that there east west north and south and the specific directions we had two point in. We couldn't just randomly through our arms around. So he really he had this professional standard. Like if anybody checked we were pointing to the east when we said, he's what was the first time. You got paid to act I joined both unions when I was fourteen so a sag at the time now after I joined sagging equity when I was fourteen and was in union plays and in union movies, and even a pilot called the happiness and. Yes. So fourteen. Were you like going off to were you taking advantage of your schools leeway and just heading off to auditions could. I mean, I did, you know women of any age do not get as many additions as men or boys. But whenever I could get one. I went to it. Of course that were you auditioning for what was sixteen year old Carol canes type was sixteen known at sixteen fourteen. I think I graduated when I was sixteen got to being carnal knowledge shortly thereafter with that Mike Nichols directed. But what was I did team for mostly theater kind of part? Well, serious than those days. I was a serious actress in those days, I'm I addition for the Prime Minister, Jean Brodie, I'm Broadway thirteen times and do not get it. I just thought I was would not survive. And then I did was lucky enough to get to it on the road with the fantastic Tammy Grimes who we just lost. And that was a great experience. One of the things that I love about your character on commission that is that, you know, I think it in many ways like parts of your career have been defined by the fact that you have a really distinctive voice and a really distinctive looking. I'm you're very beautiful, but you, and you have this sort of wonderful, grand hair and always have and that lends itself towards you know, you've often played mousy characters one of the things that I love about Kimmy Schmidt. Is that it is? So undeniably you, but it is also the furthest thing from Massey character. It's a character with no limits. No censorship. Exactly. And great writing. I know that's kind of fun to just get to say any in fact, some of the things I say just shocked me, you know, me. Lillian does things that I would never do IB way too self-conscious for so his kind of fun to be legally asked to do some checking things and say some shocking things sometimes the jokes on Kimmy Schmidt. And this was true of thirty rock as well are so fast in dense. Unlike so complex that I lose them as a viewer, and I'm a very serious comedy viewer who prides himself on not missing anything. Right. And I miss it. Sometimes. And I wonder it must be extraordinarily challenging to nail every one of those intricate. Joe they hide but thank goodness Gina fan. Robert Carlyle, a very hands on their down there on the floor with us. And if we don't get it, we do it again. And they explain it, and they fix it until it's until you got it. They don't go away from it. And then the other thing is about Kimmy, which I've never experienced before is that there are things that I say, I'm Kimmy that. I don't understand what they mean at all so up to date almost like a head of time. You know, and they are things to do with the the modern Computerworld and everything that's hip and cool and of the moment, and I don't know I've got references to, you know, things that I say, I just say them and people laugh, and and then later I say, well, what does that mean? Sometimes I'll I'll try and understand what it means before say, and they try and explain to me, and I sometimes stood on understand..
"jean brodie" Discussed on Little Atoms
"And you talk about we'll talk a moment about some of the writing process of that Novo in the essay collection just reminded us before we do the novelist about. So the novel is not about Scotland. Let you do talk about whether title came from. Yeah. I think I mean, the whole story of where the title Brom is like I was trying to write this autobiographical novel as I talk about later on in the in the collection, and it is it was a very different novel and the Edinburgh that is published in Edinburgh that is in my manuscript files. They do have a relationship, but the first draft of the novel was about someone like myself who was thinking about how he had these two very different families one Korean won scotch Irish American, and the sort of pushing pull between them culturally, and how the only thing that he could imagine present that would satisfy both him both of them was if he went to the university of Edinburgh, which you know, at the time, my grandfather thought was like Creon grandfather thought it was the finest place in the world to study, literature and. I don't know why he had that opinion. He was a he's a former diplomat and former minister of fisheries in. In korea. He knew he was a worldly man in new a lot of these things. Is it is out of reputation that you would put with the university of Edinburgh. Oxbridge? Oh, even the comparison to the Iowa program. Hey, would probably be like them university of east Anglia's creative. Right. Yeah. That's what I was thinking. So it's so I do think there is something peculiar about his affection for the university of Edinburgh was never able to discuss with. You know, like, yeah, it's a beautiful city. And my mother, you know, she she's very proud of her Scottish heritage. And so she also be very happy. If I was there, and that was that was something that I was playing around with the novel. None of that state in the book, but the title stayed in the title eventually came to refer to this part of the city of Edinburgh where so many people died during the black plague they rather than remove them to bury them they simply buried the neighborhood. And it's still a little hollow underneath and it was something that was introduced to me in the here. So it was it was nineteen ninety when I went to that city for the first time. And I was in a game lesbian cafe Enron. I met a journalist and Tori MP who took a liking to me in decided to Techni on a car tour of the city and just show me around. And there was nothing. There was nothing illicit in. And it was really quite kind of them to do. So. And this was one of the things that they told me about and it just it stayed in my imagination. It was such a powerful thing to learn. I think we also saw the the house where the private miss Jean Brodie was filmed. It was a it was a very gay car tour. That was what is not about. That's what the novel is not about. But that that relationship to the past. However, where you bury something instead of taking it out and fully fully dealing with it that is essentially the metaphor is where the title comes from. And that's in the that's the novel. The novel is about it's about the legacy of sexual abuse. Essentially in the life of a young create American man who while he was going up in Maine. He was in a boy's choir. Professional Boys, Choir her, and the director would eventually be charged with fifteen counts of child sexual abuse. And he is he's one of them. And you know, he's ashamed of his silence..
"jean brodie" Discussed on WBZ NewsRadio 1030
"Break. Paul. Welcome aboard. Hello morgan. Sure, you probably haven't got this one. But I don't know I just logged on about thirty minutes ago. But one word song one word artist. Jean? By Oliver, wasn't it. The Prime Minister Jean. Okay. I miss Jean Brodie nineteen sixty nine. All right. You're qualified. Thank you for the call by enjoy the rest of your weekend. Glenn? Hello. Welcome aboard. Am I on? That's why I said Glen. And welcome aboard. I didn't use it here. A funny noise. And I didn't. I know no one else is going to get this. This goes back to my glue-sniffing period. But I couldn't resist Dolly dagger. By Jimi Hendrix from the rain will bridge the first track on side one. Original vinyl say the song again jolly dagger. She drinks her blood from jagged edge, come on baby. Dacre? Yeah. It's a wild to could face shifting in it, and Leslie speakers, you know, how do we know the kind of stuff he played his Qatar back Hendrix? Side. They came out with, you know, unreleased material dead out marine will bridge. All right. I don't know what that says about me. But I had I knew no one. I forget that. Well, I opened it up. I just think any title with a woman's name. And there are ten thousand eight hundred twenty three more Doug, call me woke me up. And he goes when he gave me a bunch of them. But that's not one of the one. You gave me go to the game too easy. Okay. And you wanted to show off. Yeah. Right. Dolly dagger allows you to show offs. Thanks. You welcome. I can't wait to co Jordan this weekend. He was filling in this week. Did you call them? Oh, yeah. Eat a mean, I used to work on Robin young for me. Yes. I am. Hi. I haven't given up. I know up on. Young. I haven't given up on Mickey Dolan's I have. Kept on keeping on to keep on. Oh, I love that. All right. Curtis mayfield. Yeah. Well, it was when he was the impressions. Right. Right. Truckin say goodnight. No. That was Eddie kendricks. What I meant. All right. Sorry. Thanks because I say go Joyce in Weymouth. Hello. Hello. Joyce. Hey morgan. How're you finding you? I'm doing. Well. Thank you. I don't know if anyone's said it yet. But what about brandy by looking glass is an excellent one. Is a port. Else's thing. Great song. Yes. It is. I say. I sing it. But I'm not supposed to be singing. I can't help myself, but I'm not supposed to be singing. When you get all these titles coming at you. You can't help. But at times, you cannot help it. I was lying there reading, and I listening to your show, and I just said, okay, I have to go and see if anyone said this, Andy, you're a fine girl. And what a good wife you would be. Okay. And your eyes would steal a sailor from the sea. Excellent. All right. Joyce. Thank you for that. Call. Thank you very much. Have a good one you to ninety nine. I'm guessing this Karen from Wisconsin. I are you guessing her you. Well, you're right. All right. You're right. Okay. Salary has already been. It asks, okay. No. Bobby Darin known for me. Right. Okay. Got. And it's interesting because Bobby Darin, married the woman who played Tammy saying. Yeah, you're right. That is art imitating life. So the shirts are going out now. So I can still keep looking forward to like. Yes. You can did you win one past month. Then I'm assuming taking care of it. I look I one one. You know, and it never came. And that was probably a Tober. Well, it was next step puts everything, but if somebody got on then I'll still look forward to it. Endeavouring to catch up. Okay. Thank you. Julia weekend Lebel. Hello. Hello there..
"jean brodie" Discussed on Popcorn with Peter Travers
"But we definitely I think we really had hustles beforehand really got to know each other very well being barris in infantry. Just. Yeah. Favorite digit? Pitch about Queen Anne as we see in this this poor woman doesn't have it easy with her health. She's royally messed up so many ways she had gout and she had. She was also she's a very big woman, and sort of lame said, she couldn't move around eight lot, probably from depression, and Osas had shed an eye condition. Yes. Sort of suffer mental health most of hat. Let's life. I get that was a real selling point for you. If your go said, he said, you know, you get to be really physical mess. Yeah. Bring it on. I'm going to do this. I wanna do this. It seems like you're fearless. In terms of what you'll do in as Queen Anne having. She has days where she's not looking her best. Yeah. Yeah. And that's what I know. Richard vises characteristics. Say do, you know wear that you look like a badger, and she goes. Do this. But that's that's that's the joy for me because I'm not a model, and I think you should be able to. Horrendous and it'd be funded humanity. It's I that's what I love doing. You you play character. So that you're more comfortable playing that character than you. Are you even though you've seen great you seem like? You've got a smile that's his coast the sunshine has ever seen. That's a nice thing. So what made you wanna do it? What was it in your childhood and happen to you nothing? No trauman. All very lovely loving parents. Nice happy family. This is we can go now. Yeah. Left people. I just wasn't anything else. School try nuclear physics. This academic. Just couldn't really find anything. Did a school play time at sixteen. Now. Could be an actor. Connects came from my mom's a nurse. Done that. And you get this part at six was it in school school play. What was it? Jean Brodie the prime of miss Jean Brodie in what role did you play team Bruti? Well, there it is. I'm playing Jean Brodie. Than I am. What it meant to seeing it as an adult. Wow. We will doing sixteen. We had no idea what we would inning. Well, you know here in America, we have if you're like me and hundreds of other people that I know we see you remove all watched broad church. We now have BBC America. But you in in your homeland are people stop you on the street for any reason on earth because you've done all those comedy shows. So when people come to you and say, we'd love you to be in something you'll say fine. If it amuses me, I'm going to do. Yeah. Well, you know because I do love my job. But it's all kinds of jobs. You get to be all kinds of people. Yeah. Being an actor. But sometimes if an audience, and it's so popular show is so popular where they say..
"jean brodie" Discussed on Xtra Sports Radio 1300 AM
"I really did like that. They punted the ball to is right there. Because we knew that we had a shot then kill the game. If we could kill the clock. And we did it. Look at any time the reaction to the opposing coach is glee. Way to make a decision like that. You know, you've made a bad decision. Right. Pete Carroll was happy that they punted the ball. And just as Mike McCarthy said, Kenneth Clarke and Mike Daniels were injured and what are the Seahawks? Do they pound that they found that they found it? And that's what they did. It was so easy. It was Mike Davis. It was Russell Wilson running for a first down Mike Davis again for I doubt. And at that point no chance to get the ball back into Aaron Rodgers Hans-Peter. I I agree with you completely. Even if you concede a field goal there. You still have a chance with a guy who is a master of the hail Mary to win the game. And give your team that galvanizing moment that can propel it down the stretch this to me, and it's very easy to say. Well, Mike McCarthy's this problem is that problem, I appear Chris Simms has all the time. The offense is in imaginative. This is a concrete moment where it all came down to one moment. It all came down to one decision and to not leave the ball in the hands of your thirty three and a half million dollar quarterback. Under those circumstances is inexcusable. Yeah. And the two other. Problems. I have in the in the second half for Green Bay number one. They burn they burn two timeouts, and I'm not saying, they burn them cavalierly, but you have to think that at least in my opinion. Sometimes I'm not saying you should aim to take delay of game penalty. But all I am saying is that when Aaron Rodgers is my quarterback. I'd rather have to make five more yards and keep a timeout. Then take time out. Whatever was six minutes left in the third quarter. They burn timeouts too easily number one. And here's number two. I sometimes think that I'm watching a game. When Aaron Rodgers is playing lead. He can do anything. He wants at any time. The fact is he's just like any other quarterback. He's going to have some crappy plays. He's going to have some plays. He's like to have over. He he'd liked to have over, you know, like the third into worm-burner, then he threw into the ground. But I just think over and over again as I'm watching this game. I went back and figure this out my since Christmas day two thousand fifteen the Green Bay Packers are twenty one twenty two and one k and Aaron Rodgers is played all but either seven or he's played all but nine of those games. So it'll the Packers are basically a five hundred team with Aaron Rodgers playing. And and, you know, remember the prime of miss Jean Brodie when you were ten years old and you wanted to go see this movie. Well, right now the prime of Aaron Rodgers I'm not saying it's being wasted. But I do think that the Packers have to take a long look at themselves after what is likely to be another non-playoff year. And just say are we maximizing those skills that you just saw that ridiculous ability to throw a ball that no one other than Patrick Mahomes? Asterisk can make first of all I didn't want to go. See the prime of miss Jean Brodie. I wanted to animal house second of all they are wasting the prime of Aaron Rodgers and third on that beautiful throw to Davante Adams that led to one of the time outs. And that falls back to look at. This isn't the first time. Aaron Rodgers threw a deep pass on a running clock where you've got play clock that you've got to honor before it hits zero. So why aren't they getting down the field and getting lined up, and who does that fall onto I guess Aaron? Rogers to a certain extent. I don't know. It's not like he lingered and celebrated for twenty seconds. You get the guys down the field. You call a play, and you go, and and at a certain level that's on coaching. I don't know. Maybe they were celebrating too much on the sidelines to get ready for the next play. But they had to call that time out right after that play because it took them too long to get lined up and get ready for the next play. And they would have definitely they could have used that time out, and they should have had that time out. And it may have been a different thought process down the stretch if you know, you can stop the clock more than once once Seattle has the ball back. But look this isn't all about how the Packers blow it. We got to give some credit to the Seahawks. They were down fourteen to three in the first half. They fought back. They took the lead seventeen fourteen before the half than the Packers. Go up again twenty one seventeen Peter I thought it was going to be forty four forty one final score until it all kind of went the other way in the second half. And part of that was the Packers went into a punt punt punch shell but the Seahawks. Hang in there when it felt early on like, you know, what this just isn't our night. Right. We're down fourteen three the Packers have found something special. We can't get anything going. We have to give them credit for the fact that they did get it going. Russell Wilson did make the throws he needed to make. He was dropping in some beer. And it was it doesn't look flashy one. Russell wilson. Does it when Aaron Rodgers does it it looks like it's special when Russell Wilson. Does it it just looks like, okay? He threw the ball and the guy caught the ball. But Wilson got it done last night when you need needed to and for as much as we're gonna knock the Packers. I think we've got to praise the Seahawks too. No question about it. You gotta hand it to Russell Wilson. Because he made enough plays when he absolutely had to make plays. And you remember the pass he threw over Doug Baldwin's head in the end zone in the first half Doug, Baldwin wide open. You know, which is very uncharacteristic Wilson. He's an accurate guy as we've seen from this tape right here. But my problem I think with with a lot of what happened in this game. Mike is that by the time. Green Bay started losing guys on defense. They just didn't have the cavalry to pick them up. And look no team has a limitless supply of impact players on either side of the ball. But I think once they lost Clark once they laws Daniels that really changed the face of the game. Yeah. Absolutely. When you have Chris Carson, Mike Davis. Rashad penny all three guys able to contribute on the ground. And Russell Wilson who isn't running as much as he used to. But when he needs to just like late in the game when he ran for that easy. I down he can still do it you combine that with the passing and the Seahawks now at five and five look, we know that the Packers have to draw that tough inside straight. If they're going to get to the postseason and Peter if they can't win on the road. What difference does it make? If they get to the playoffs if your own five so far on the road during the regular season. You're going to go on the road wildcard divisional championship round and win. I don't think. So. But this hawks team mean this should scare the Rams I said yesterday that the red if you're a Rams fan, you should go out and buy a foam Cheesehead and route like hell for the Packers tonight because you don't want the Seahawks in the playoff field. You don't want Seattle coming back to the Coliseum for another round. They've given up thirty one points twice to the Seahawks. They don't want the Seahawks again, they could be a very dangerous team. Now if they can. Keep winning games down the stretch and get in is the five or six seed in the NFC. And conversely now with the Packers being four or five in one I said at the start of this schedule stretch, Mike there that was the fourth of the five games that was the Bataan death March March of all NFL schedules this year because think about it, you know, you go to you go to the Rams you lose, you know, when Ty Montgomery makes dump play the two minute warning you fly back across country. And then go to New England the next week Aaron Jones fumbles on the first play of the fourth quarter of a seventeen seventeen game. You lose that one by two touchdowns. Then you come home, and you and your face a Patsy in Miami. And you beat them while surprise. And then you also obviously go to Seattle on a short week tougher. Everybody particularly the Packers. It's insane. That a team plays a late afternoon game on Sunday insane. And then gets on a plane less than forty eight. Eight hours later to play a game that's going to define season. I think that's just an absolutely crazy thing. But having said that Green Bay Mike needed badly to win one of those three road games. They won none. And that to me, I think I'm not saying it's the death knell for Mike McCarthy. But at the end of the year when you look at a team you look at mistakes made late these are two mistakes that players made to lose the first one. And I would argue that last night was a mistake that McCarthy made that help lose the third one. And at some point you just say we're making too many big mistakes at huge moments of games. And we got we got to go down a different road. Sometimes it's just time for a change. And I mean the way this team is going I will be surprised right now just the way they're going if they keep going on this path. I'll be surprised if they don't make a coaching change. Let me put one small button on the point. Because then we have to take a break. Mike McCarthy now reports directly to Mark Murphy, the CEO at a team it wasn't that way in the past. Mark Murphy played in the NFL. He knows football. And he's going to be able to cut through all the smoke from last night and get right to the point that you, and I are making did Mike McCarthy should have left the ball in the hands of his thirty three and a half million dollar quarterback on fourth. And to Murphy is going to get it. And it's going to help Murphy. I think eventually get to the point where it's time to move on. We move on moment return is drew Brees having the best year of his career. We'll discuss it right here on PF t live. My number two does not look like a number two. I don't know what to call it. Is there? A number three..
"jean brodie" Discussed on WTF with Marc Maron Podcast
"And then what the teacher identifies as like an, and then it helps you see yourself and something shifts in yourself like I feel like my needs to please is high that or it was a decade ago that it took it took me a watching to really learn something right now, it makes sense. But it seems like being present in listening is kind of key. Yeah. That one, but it's Turkey because he liked to get to a place where you're not just thinking about. Okay, here comes my about to say what I'm going to say sure comes look at that other person acting. She's good. Wow. Okay. Oh, hi. Yeah. The kind of. Yeah. Or or or like the thing of like doing all your homework, and then trying to show that you did all your homework. Yeah. I'm not good at homework with anything. I'm sort of like glass Minniti kinda load up my head kind of person. Right. And sometimes I've worked, but like I think making choices that trick right? Like, I mean, I can I do prepare. But like a backstory, it doesn't help me help you. Sometimes I you know, I did I did a play in college and the direct the student director. I worked with was like all about backstory, and she made us write these elaborate autobiographies and actually we're doing the crucible. And like, it's all everything that we invented took us further away from the play. I would think so like it. I think those I think that character autobiography would ever is only helpful if it helps you engage with what's actually there. Well, that's the thing. That's one the one thing that like I gleaned at you know, and I was judged mental of of David mammoths approach early on. But but I think it is on the page. And I, and I think that if you trust the writers that you're gonna find your way to that person. Do I do I agree with you? So you start doing theater? Yeah. So a lot of theater I did a lot of eater. I've done like a dozen plays big plays. Yeah. From white when you were like just. When did you first start doing that? I was I was twenty two about to turn twenty three. When I did my first play in New York. I did the Prime Minister Jean Brodie with Cynthia Nixon at the new group off Broadway the new group. Yeah. Remember that? And you're twenty two I was I turned twenty three during that production. And now, did you know Cynthia I had never met her until my call back for that. And how was that? What was she great? She was great. I will say like, you know, in terms of that like Hollywood royalty. Like, you have it easy kind of thing. I like I was so eager to dispel that. Like, I I think that's part of the reason that I worked so hard at the beginning is that I really wanted people to never be able to say that about me never thought of changing your name. No, I like my name. My name's name some people change them though. I know. But now that's a lie. I did think about it. I just didn't think about it for very long anyways. I memorized the entire play for the call. Back because I thought they might throw something else at me, and they did and I always already off book. So I got like a gave myself a big leg up. And I got that part. I think partially because I was that prepared and Cynthia was great and taught me a ton. And she was also didn't hold my handed in the least. And that was also really good. And you were the two major characters. What when when you just taught by being with her. She actually snow just by being with her actually like there there were like this guy named Ritchie Coster an actor name, not Roche an an acronym. John pink out, and they were all in that play with me..
"jean brodie" Discussed on Kermode and Mayo's Film Review
"To me and he wouldn't even hardy willis that's what when that famous actor freebie empowerment joseph gordon levitt thank you i'm sorry i've really have old man's head on today when he first steps out onto the onto the onto the rope and we saw in nine mex remember that the expectation and it was literally like because when you're in imax any what you're up quite high and i feel like i actually watch this i saw die hard in in dirac in a building in the screening universal which is not the same as the mexican but that moment when it's the set piece when they have to walk over the plank i felt the same and i literally i see we andrew hazel in while it doesn't add much to towering inferno diehard jones skyscraper does make a nice dish in to the disaster movies your by not having a handicapped character be defined by their injury in the opening scene we learn as you mentioned out of johnson's character losing a leg before jumping ahead ten years to show him living his life already adjusted as one can to the injury the movie then sets about an average plot but ino time does it place particular emphasis on his injury as being some kind of personal hurdle that he needs to overcome so may consider this paul writing but i see it instead as a choice to try and show that heroes come in all shapes and sizes and you just get on with what they have to do not because of the challenge of overcoming such injuries but despite having such injuries tools groundbreaking but entertainment bmovie fair absolutely right it does it doesn't make a big deal i mean there are times that he uses the the prostitute attorney very specifically in order to do something that he has to do but no it's it's absolutely i completely agree with that and it's no point is it made into your journey of something to be overcome no absolutely not heroes do come in all shapes and sizes i wish i came the same size shape and sizes dwayne the rock johnson one day mouth is he is he also fit really told me because he's huge is yours you walked past him in the thing in in this building that we're in now is he actually is imposing realize out the sun team our tv movie of the week choices this week lou tinker tailor soldier by the prime minister jean brodie gangsta number one hella high was expert five apparently mississippi grind and wally pfister's transcendence jp share and has to be hell or high water for me i want to say it's a great modern retake the west and beautifully shot and acted with some really witty dialogue but really what does it for me is the awkward but genuine way that real love is expressed between such stereotypically masculine characters i love hell or high water how kitchen the place beyond the pines film with an ambition and scope rarely seen in indy projects however it's clear from marks devotion to pull knew that he won't overlook his best performance in gangsta number one one of the strangest most versus gangster films ever made with three of the best british actors of their respective generations at.
"jean brodie" Discussed on Las Culturistas
"It's good advice and the girl sank in her seat yeah she was a little embarrassed but okay how about this for the t oh my gosh who snubbed us today canceled on him cost minute what's feet away from the door you're not going to fathom y'all maggie jill and hall wait maggie bell i pat regan famously called sorry maggie joe hey i don't sorry we're gonna get to patent and but you just left me hanging there what the fuck maggie don't fuck and come from we're very tired god okay i know that you will last coach reasons because of the bond of friends you might see the dissolution of that this evening honey tonight but mackey i don't fucking that we had a game prepared and you guys wanna play with us now that we did not get okay we'll play the game really quick we'll get into the evening okay so this is which maggie though and the game was going to be we were going to save facts either pertain to maggie smith or maggie villain halls so should he play let's play okay and you guys can all say at once yeah you're the co host tonight you're if we're wendy williams be the co host okay slade in mona lisa smile good slade in gosford park take great got blown up in a movie no no no now maggie smith donald jean brodie and she got blown up and best exotic gets how american hotel she quotes and she got blown up at the nf sister act two and that's why lauren hill sings that's when lauren hill that's when she sings after the explosion of maggie smith well we'll get an inch and more into more oh my god.