19 Burst results for "Jason Mewes"
What the immune response to the coronavirus says about the prospects for a vaccine
"With a number vaccine candidates against the corona virus sharing promising results in clinical trials and a growing number of studies elving into our mean response to infection. The spotlight has turned once again. On the body's defense mechanisms. I think two questions that really relate to the ability of the vaccine to protect us and our ability to fight off a second infection and so that is the quality of the immune response and the duration of the immune response this week. I'm joined by professor. Eleanor riley from the university of edinburgh to dove into these questions and more. I'm nichole davis. Welcome to science. Weekly ellena you came onto the podcast in july and talk to us about immunity and covid nineteen specifically the relationship between antibodies and immunity. So let's start with a recap on the major players in the immune system that are of interest when it comes to an immune response and potentially immunity so antibodies are protein molecules that are produced by immune cells kobe cells and these cells live in our spleen and narrow and they secrete antibodies off. They've been exposed to a foreign organism such as virus. There are two types of cells that produce. Antibodies on short-lived cells that produce. Antibodies for a few weeks national to the first line response and then some of those cells transition into lonely cells that goto a bone marrow and can produce antibodies for months years. Possibly even to case and then on top of antibodies. have that can kill virus. Infected host cells t cells the two types of t cells one of which we think of such of the conductor of the orchestra of the immune system and these kotei health cells and they very much help the b. cells to make antibodies produce. Growth factors may direct the direction in which the be cells developed and they will still give them signals to turn into cells and then there are the cdte cells and they actively kill virus infected cells and then Antibodies can also bind to these specific cells and help them to kill cells so they recognize little bits of virus on the infected cell bind to the infected so and kill it and then there are cells which are less specific cells that we call macrophages are neutral fills and they just recognized that. Something's not quite right with the cell. They don't necessarily recognize the infected with the virus and they kill it actually or bits of the immune system work together a little bit like you need a whole orchestra to make a good tune when you need all of these cells working together to make a good news arms. And i know you said in july that at that point it was too early to tell how quickly people were losing their antibodies. And we've got to remember here that it's a relatively new virus. What's the latest research saying that seems to have been some movement on that now. What we're seeing is if you all the data together. There's an early peek in the antibodies wants. Lots and lots of antibodies are produced to mop up all virus. That's in your body and then as that virus goes away the antibodies start to decline a little bit. Because you don't need them any antibodies anymore and they settle into a of steady class. O of antibody production. And that's very typical. This kind of two phase response the only peak lots of antibodies followed by sort of standing level of antibodies. That nick for a long time. That's very typical of an antibody response and it sort of relates to the short lived long lived cells. You have lots of short-lived cells making lots of antibody that off and then the long lived cells who that fewer in numba keep on producing. Antibodies for much longer so yes. Let's talk about these long-lived b. cells in the no said the t. cells. What is research telling us about what happens to them and how. How long do they hang around for. So we don't have much data on those are actually quite difficult to look at in humans. They tend to live in the bone marrow for example not very accessible and so we tend to rely on mathematical modeling of the change in the dynamics of the antibody concentration to predict what's going to happen even though we haven't actually been able to see it because it hasn't gone on long enough so the moment the infants is that we have suggests that things are probably okay these cells behaving as we expect them to the was one pay published early on suggesting may be a little bit of a fault with the production of these long midsouth. But i'm not sure that that's been replicated in other studies. I think i saw a preprinted study. That hasn't been peer reviewed yet. Which jested that these visas and t so's lost for at least six months is that. What are the problems here in terms of measuring this so we only have six months data at the moment and the virus really hasn't been around that long so what we can say the moment. Is that the cells assisting for as long as we are able to measure them at the moment obviously in six months or another twelve months time. We'll be able to go back to those people and say have they still got those cells. Yes or no. But in the meantime just looking at the change in the dynamics of the response and mapping it onto what we know the other viruses. My prediction is that these that there will be some long lift immunity to this virus. He said there might be some long term protection. How long term are we talking here. I mean i've seen a lot of people saying well current viruses such as that of course common code some codes of course by coronavirus is of course the protection only lasts for say a year or so. Do we think that our protection against the corona virus that causes covid nineteen mike baxter timeframe or or could it be longer. I think it's very difficult to say at the moment. Say all of the data. We have suggests that these antibody responses are going to be at least as long lived as response of corona viruses. And possibly i might think even probably going to last longer your immune response tends to be proportional to the level of threat that you face so the common cold corona viruses really only colonize our upper respiratory tract so on nose throat and so the virus doesn't go very deep into apology and we make rather grief that effective noon response nose and throat that controls it this coq nineteen causing virus goes much deeper into our bodies it goes down into our lungs into bronchial and therefore the immune response tends to be stronger and they struggle we call systemic immune responses do tend to last longer because they are recognizing that there is a more serious threat that has to be dealt with. Do we know if factors like ethnicity gender age factor in the scale of the immune response. She said stronger. Immune response to your first. Infection is is more likely to me. You have great protection against the second infection. Those factors correlated at all. There's very little day to so far on ethnic differences in the immune response the data. That's coming after the vaccine trials suggests that there aren't any major differences in at between ethnic groups in terms of whether the vaccine protects them will not but we haven't yet seen lab data on their antibody responses with at t cell responses. There is a lot of genetic variation in the immune response. People be aware that some people unfortunately have very severe genetically determined immunodeficiencies. That's just the tip of the iceberg of genetic variation in the immune response and some of those differences do have geographical and ethnic components to that certain genes that either make good or bad immune response on more common or less common in groups countries. But we don't yet know if any of that is going to influence really the totality of their immune responses. We just don't have any evidence much by age. It feels like ages is. It's very important given that the older you are the more risque from caveat nineteen so there are two components to that one is whether you are able to make an immune response again's a virus. You've never seen before and there is. I think really quite good evidence that you ability to make a completely new immune response does decline as you get older. The other component is that a lot of the disease we say in coke nineteen excessive inflammation. And there's also evidence that we get older with less good controlling inflammation so it's a little bit of a double whammy as we get older way are less able to make an immune response to a new virus such as the covid nineteen virus and if we then get the viral infection where less good at controlling the inflammation that it causes a so we know there are several different vaccines. Which looking very promising. You have the rene vaccines at you have vaccines which used a chimp. Virus to bring genetic material from the corona virus into cells. The question is is the immune response that generated the same as it would have been to a natural infection and do the t. cells and so on hang around in the same way. The vaccine is just a tiny component of viruses this spike protein which is on the surface of the virus and so if you vaccinated with spike protein. You make antibodies in tesol responses just to that protein. If you get the virus itself then you get many many more pro teams that you're exposed to a new may make antibodies to some of those. So you responded more limited but you might also say that your response is more focused because it's actually antibodies to spike coaching a really important for neutralizing the virus so the vaccine in juices a narrow immune response but one would hope it would also be focused on therefore stronger on the base the matter and would it be expected that this will provoke a stronger. Immune response natural infection. I've heard some people say that actually vaccine can producer a strong response it coun- if they initial infection is quite mild say with virus like sauce covy to which induces very mild infections in some people i would expect the vaccine to tobacco to jason mewes which is much stronger than you would get after nascent dramatic or mild infection. People get serious dose of coca to make a very strong immune response. And i doubt if the vaccine it doesn't need to be any strong national adopt if it is when it comes to and viruses the coups common code. It's been some concern that these viruses somehow elude the memory b cells. and so. that's why even though we have thousand cells to to the common cold viruses. We will often get reinfected with them. I wonder if they're those same concerns about the coronavirus behind covid nineteen so there is a little basic data. There's one paper that suggests that the sauce kofi to virus that causes covid nineteen disables particular pathway in the b. cell response leading to a poor long term memory response but these experiments done in the lab in a in a in a petrie dish. And i think it's too early to know if that's really what happens in humans so i think we do need to be a little bit cautious and we need to be aware that it might happen. Good news is that the proteins that are believed to cause that problem are not present in the vaccine so even if it's a problem in natural infection it shouldn't be a problem with a vaccine
"jason mewes" Discussed on Snarf Talk
"So well, you know basically same thing. Okay. Yeah, so that's a shame. I got some Marvel Cinematic Universe news for you. I like me some Marvel Cinematic Universe. The MCU has said that they are they have brought back or off bringing back Jamie Foxx to play Electro again in Spider-Man 3. Why are you joking me? No, seriously. This does not sound good. Well, apparently they really liked the character why I don't know but he was in isn't that like widely hated gym. Yes. Well that movie was I don't know about if he wasn't scared. She was very good at it. But no that is a big character. I don't know why you just so they're gassing this point because it's a completely separate Universe. Why are you putting the same character in a movie right with a different Spider-Man Spider-Man? I don't he's in final talks. So it's not a I guess it's not a done deal. But he's a guy talks to play Electro not smart, which he played in 2014 S Amazing Spider-Man 2. Yeah, so might have something to do with the Multiverse though. I don't know it could be. Hopefully the I have faith that they will do it better because everything that has come out Spider-Man related in the last five to six years is phenomenal. Yeah, I trust them a good job. So I do trust that they will do a good job with that. But that character is not good. One other quick thing that I got I think we need Roundup a starf talk road trip, perhaps. Oh, I like road trips. But how are we going to do this with covideo. November 1st, Kevin Smith. And Jason Mewes are coming to Chicago for an outdoor live podcast November 1st outdoor live podcast Chicago there from California. How are they going to survive know if they really know what they're getting themselves into but and Kevin Smith is pretty skinny now. Yeah, I mean got you ain't got that, you know that installation that it used to have so I think we should go to that Jay and Silent Bob get old is not my favorite podcast. I'm not going to lie. Oh, I don't care but watching it live is a way different experience than listening to the regular podcast. Yeah. I did. I did go to one Jay and Silent Bob get old podcast that you ditched me for. I know so hit by myself like a jackass every time you tell me the phone number. Watseka probably the 47th episode that this has been brought up. So anyway, I think we should go to that November 1st. I'll probably still be in the field sister's birthday. I think we can figure it out. Your sister-in-law is in our she's watching right now. Well, your birthday is September first lady and I'm going to go to a show for you and see Kevin Smith and not call you or I'll be busy. Happy birthday to Katie. That's all I got for news. don't know if you got anything else. I really don't not really I had no news. I told you that out for told me you had all the news I didn't that was all of it. I do have an article on everything coming to Netflix Disney plus HBO Max Hulu and Amazon Prime in October off to know it seems like a lot. I'm not going to read them all..
"jason mewes" Discussed on The Adam Carolla Show
"Here's another great moment in local news you who is trying to figure out who this woman is. She's accused of urinating on potatoes at the Walmart in West Mifflin. That's a a great moment in local news now back to the Adam Cole at Shell will say part of this thing of US blurring during the lines between men and women women doing a lot of Dukhan and Piss and out the open used to be that was the realm of the dude the dude take the Piss by the side of the road might take the dump in the vacant lot now. I'm hearing a lot of stories about liberated ladies Drop Dunkin donuts. That's it's thrown at it people pissing on potatoes as the crocodile hunter thing so you never think in a million years why tackle crocodile renting and grab it. Oh One guy did it was like Oh everyone I can do it. What do you think trae how women have been limited liberated to the point now where they can drop it to sound public just like the men can probably probably asked her to do it and I'll really German anke into his stuff behind every great woman that my son Said <hes> things have changed now? You can't tell a won't damn you look good. You can't say that no more so my son Said Dad you have to pretend that you just walked into yourself and your cell partner said exactly what you're getting ready to say to that woman so if I walk walk into my cell and myself partners damn good genes. I'm killing you so right. The psych is a good way for me not to not not to get slapped now. Does your son use that metaphor for everybody or just people who have done hard time like yourself. Well you know what it actually actually works because if you're like in close quarter with another man and he tells you wow I love your hair. You might get a little mickey. I don't know how would you feel if I told you well not that late. Check I would take it. It's nothing but a compliment no but I mean if I if I told you I I like it is well from you Danny Trae oh I would take it as a compliment from a strange dude on the posse was just built like you would be a little ah so you're gang or without your I._M._D._b.. Credit I would be freaked out but you haven't like you're quite welcome madness in the method name of the new movie it's in theaters and it's on demand and it's coming out Friday. Don't never say yes. Yes Jason Mewes unless you know what he's asking. He said Danny will you do this little thing in the movie for Me Yeah Jason and you know this so Jay and silent Bob Jay's yes. I'm just cool character for you. Ah Jason's doing standup now believe that <hes> it's got a baby. It's wife have a baby as such cute. Well that the you find out when you go out and do stand up when you go into lobby see the poster of Moose coming the next week he can. I saw Jason Mewes on there and I said Oh Jason's doing Stanford. He probably thought anything about me. Danny <hes> you and we know oh you got the trae hosts tacos and trails canteen..
"jason mewes" Discussed on Doug Loves Movies
"It's not Roller Derby. It's not called roller girls that would've been a great title for it as with roller girls. What's it called something else? Don't say thousands of active game happening yeah. It's called whippet already. Originally is a winner then yeah did have new Jack City. I believe I think Jason Might Still Drew Barrymore. She's in it okay. Wow the whole audience how dare you I love you at right to the Internet approve well. Once I was eliminated. I forget she must be in it very briefly. I can't even remember being in a she's alright. I'll still concede the winter richie really okay okay. He's got another one right next Monday. She Oh maybe not oh your lifeline about writing very finally completing the trilogy. Yeah yeah all right yeah so I'm calling your the Winter Dude congratulations get your prizes. It's a bag and then a couple of items. Who Was it you were here doctor? You go dude congratulations. That's some good stuff way to go nice work all right. Let's do some some plugs. That's where we're all here for. Josh Molina West Wing podcast Western pocket pack the West Wing weekly comes out tonight. You know we've forgotten publish tonight because we're here doing your podcast and we got so your show's coming out late because L._A.. Yes yes exactly but it will be honored on weekly until January twenty twenties all rat yeah yeah yeah the big show that sold out so don't go to that but listen to it. That's a great thing about like when Douglas movie sell out. I could tell me a week still listen to that's right and they go no. I wanted to be there. We'll put but says the same plug. Do you have other things to plug greasy. I have another podcast called Song Explorer. What happens on that so good? A musician breaks down how song of theirs was made and it's it's intercut with the isolated parts of the songs you can hear what's actually going on in the music and it's also a making it and yeah what's an example of the kinds of artists you get on there. All different kinds metallica YouTube Youtube Bjork's. Yeah that's great yeah. That's also all right a lot of movie and TV soundtracks in there too okay cool. Check it out. David Hunts Burger. Yeah I have a bunch of live stand up dates coming up starting this weekend in Houston and Austin be at the secret group in the room and then <hes> watertown South Dakota and Denver Colorado than <hes> Portland and bend no no Bend Oregon Boise Idaho San Francisco Sacramento and Minneapolis in the beginning of September. All the tickets are David Hans Berger Dot Com and the special one headed to be streaming for free on Amazon prime..
"jason mewes" Discussed on Doug Loves Movies
"Amount man jody or you can go to your person go. Oh yes my person. Eduardo uses have your neighbor is what you're looking for there yeah a vendor's endgame then avengers and grossing film of All Time Right Breaking News Spiderman far from home okay so I if you say so I haven't seen it. He was also an Alita Battle Angel H._D.. Charlie's angels yeah very good. What does that make you think of Jason? He just said Charlie's angels Bosworth Charlie's angels two the full throttle. What's it called the throttle Charlie's angels two full throttles guests? Yes okay correct. Josh Josh Snakes on a plane fever pitch. ooh That is where she is clearly going to win because he's already they go out to so many so many trilogy that has been finished off. David took me a second black snake. Moan Nice Drew Barrymore was so good. I didn't get around to seeing that movie because I was chained to a radiator yeah when it came out was really ironic. How would you know you didn't see it but it is yeah very I saw the trailer? I know what happens from your radiator Internet radio chasing so it's playing and trailers but he never got the movie yeah. I don't you know Charlie this deal movies yeah. They haven't done a third one. Do the new reboot now new Charlie's angels. Maybe she'll show up in that. I <music>. I'm I think I'm I can't think of any other movies now. Bizarre was nick. Samuel Jackson's like all the movies. I'll take I'll accept that I think he shows up in the end credits that all right Josh ironman airman two yeah why not Rishi Captain Marvel Yeah since I have two people as my lifeline and I and I know the actor sure and some of the cast from the movie I'm taking up. I just don't quite have the name. Could I use one for this and still hold onto. The other. One for like crazy plan is that why can't I just do it. Not My or just ask them for something. Get something else from them and maybe this other thing will come back to me by the time it gets to you all right guys. What do you got? What do you do the regular magnay say for Sam Jackson? Thank thank you hate to blow at this early because I feel like they gotta deep Deepa catalog. This is bad news Jason. Oh Thor Captain America Okay Josh The avengers movie. We haven't mentioned yet. What's it called avengers colon something you WanNa accept that you told him full-throttle you're right? Let me it helps you. Similarly vendors similarly in what age did take place Major Voltron Rishi thought might ready case was just as reasonable but you're what my request was seemingly as much of a reasonable sort of but to make eye contact and I'm working this shit at Captain America the Winter Soldier Okay God damn it yeah I was gonNA guess both of those and like the age of I do that one okay I can see it Chris Cooper yelling turn them loose and then Samuel Jackson's is on trial. It's what movie is. What's the name it's about race?.
"jason mewes" Discussed on Doug Loves Movies
"Message. We'll be right back. Hey everybody don't forget to go see good boys in theaters on August sixteenth and if you're in the traverse city Michigan area via good boy or girl and come see me doing three shows over three days of August first second and third go to T._C.. F. F. DOT org four dates back to the show all right. We're back. who were you playing for? Josh Molina No it's her name should be for Casey. Positive Energies coaching for me. Yes yes he's. He's hoping that you will sure racing blind. I couldn't see the guy couldn't hear it now. They're both wanted for Casey. No Evil Hear No evil you know that movie C._O.. Evil hear no evil yeah with the comedy Legends Gene Wilder and Richard Pryor. I wouldn't recommend it to anyone who wants to keep them in. The comedy legend story is kind of a rough movie. There's a few scenes where gene wilder as a stunt donate double. They're usually like who's that guy in a curly week. It's pretty rough but case see no evil hear. No one ever caught your eye. I'm trying to keep it positive there you go. Who Do you got Richie? Yeah uh get it wrong again buddy from now on what's up buddy she playing for Zach Zach it says experience. It's yeah instead of I from the team that assembled the clerks movie. How did you do that yeah that in Airbus heard a rumor someone who's going to be here tha that and then the Legos Ackman yeah there you go? He's got a little joint yeah. It's a Lego Batman. Mini me fired from the series <music>. What one thing yeah please just because really I mean this? Is this is for you. The clerks poster was the very the first movie poster that I ever bought my on. My Wall. Freshman Year of College Chinese remembers the code I mean he wanted to ask me something on my son's coming Josh my dad no nos ninety ninety four. I was forty eight and ninety four. You're probably not older than I am. Positive Energy people a again that David what are you have. There looks like you've got a lot of good stuff with your name tag yeah. It feels like they robbed a convenience store. There's a mini ving vodka distilled from farm fresh corn born to joints look hand-rolled suspect perhaps and then tortoises by Ash Ashby confections dark chocolate Pecans S._A._p.. Cons P._K.. Sweden and all of those things the Monterey Bay David just started smoking weed. He told me before the show I did a little bit and then I haven't done it in a while. Riding a bicycle didn't do it as a teenager jerk back on and then there's the Cherie different movie parody posters this is above and beyond Chelsea. I don't even on American wedding in Palos Verdes. That's your actual where you got married and Poulter band to what does that Ben was. What's that about germ? You guys what what's inside jokes on your name tag wait. It's Ben then. I thought you said Dan. It's been what he's been on their this using. I just hope coulter yeah. I don't know let's go to. Let's get to Jason Before we've Edwardian. The Galaxy Nice Nice great job at Mardi and I like I like Sarah. Silverman is good more. That's a nice touch and look. I'm rocket rocket yeah. That's exciting so yes. That's played for Jason. I WANNA change your mind. You Good No. I'm digging. It was between <unk> abducted. Call out for me. I was torn between the duck movies but there's a duck. He had a dark here donald dark but I was thinking Howard the duck duck. Yes graduations you came in fifth right. Do not winning anything because only one of you is going to win all of the prizes on behalf of the person you're playing for devised a couple of games for us to play that we played a couple of days ago in a show where the recording lost like. Let's just play these again. See how it goes. I thought at the trick to for you to help remember Ritchie's she's name..
"jason mewes" Discussed on Talk Nerdy to Me
"Shots. Static two shots in a convenience store in shun black and white. You're probably going to choose the movie with aliens in the in the you know, the welcome to earth and so in the inches of blockbuster. I mean, I I can't blame them. But luckily, I went to I went to both movies, and I love clerks much better. But I I really as as a fan boy, as you know, all you want to do is talk about if you see something really cool. You wanna talk. You wanna talk about it with other people? You went debate with other people, you wanna talk about certain scenes, and I didn't have that. So I I ended up channeling my phantom into building a fan website. I was really bored or the computer lab one day. Took a week out and built as clerks fan website, and at the bottom, I put my Email address on there was like, hey, if you've seen this movie your fan, you'll Email me a, you know, a at clerks fan dot com or whatever. And. Yeah. People people started emailing. Hey, man, you like clerks to us cool. Like, none of my friends watch it with me. So I was a I was able to able to Nellie relate them. But it was cool. I use a power of the internet to to kind of make friends with fellow clerks fans and lo and behold, the I guess the ultimate clerks fan. I ended up contacting me and that would be Kevin Smith saw the site one day at a internet. Cafe track down, my number actually, just gave me a call. And he's like, hey, man. I love what you did. Do you think you could do more of it? He was starting up his production company, you askew productions and he had just come out of mallrats. It had not done that great at the box office. And he was just going into chase. Amy. And he decided I think Kevin's always thinking two steps ahead of everybody two or three steps. And I guess he had an idea in mind that maybe he to could maybe reach out to his any fans of clerk tomorrow. It's on the internet via a website via kind of like an online repository and archive for the two things that he's done. And then we could put up, you know, news and photos from any any of his future, productions and. And I was like, hey, can you help me on like let me think for a second? Yes. Yeah. It was pretty much no-brainer. I call me. I didn't believe him. But yeah, I didn't believe it was him. Who would? But I heard what I thought was Jason mewes talking in the background. It's hurt. It was Jason mewes J of Jan solemn Bob fame. So. Yeah. Those were the beginnings. We actually ended up building a website. He had sent me a list of things that he he wanted on the website. He 'em right after we talked. He sent me a FedEx package full of photos, and all the all this material that that he had they just had laying around the stuff that the normal fan would have when have access to. But he was put all this online. So everybody else can see it. You know, I think it's kinda cool. Maybe some maybe the fans will as well. So so, yeah, he had a holistic things he wanted to put on there. One of them. He really wanted was he wanted a way to communicate with the fans. So his initial idea was to do it via a chatroom. He Kevin started out his career in the internet using AOL so chatrooms rooms really really big back. Then I what you want chat room. Like, you want to pick up chicks on this thing. No, no, no. No, no. I wanna talk to other fans like, oh, okay. Yeah. I yeah. I guess we could put that. But I instead of a chat room, I ended up suggesting to them. Why don't we put up a message board where people can post questions to you?.
"jason mewes" Discussed on Hollywood Babble-On
"Wait, let me shoot. I got a new iphone? Oh -gratulations that Christmas gift. No bought it myself. Well, it was you gave it to yourself. I guess, you know, been a nicer somebody fucking thought about it. I don't do lists. Like Jason mewes does list. So he's just like, hey, man. I did my on wishlist, and he doesn't invoke June. So like he lets you know, smart what he wants on Vance. I still have this thing. No, people know me, and they know what I want, and they know what I need particularly those closest to men should then I get socks and printer papers so fucked up. But whatever man I got in. You know, I'm independent minded I when I bought my own fucking phone. So now, I'm gonna shoot you on hold on direct your ass and put this up you could fuck put this as a credit on. I am db motherfucker directed by. Kevin Smith have directed by Kevin Smith credits. Miam- Depaix, right? Then put Kevin Smith. You'll houser. You guys are amazing. Just in you had babies at eight. That's amazing. Happy new year. That's what I say. To the boys. I'm meeting West Hollywood. I say you wanna see some California gold. And I'll pull it out. It's amazing. Welcome to Las Angeles. You know, what they say about LA? Kevin, welcome Los Angeles. Put a dick in your mouth. That's for you. Mom, happy..
"jason mewes" Discussed on The Jock and Nerd Podcast
"So you get links to everything we're gonna talk about how to get in touch with the show. How to subscribe to the show for free that way, we buzz your device in your pocket. You get a little tingle valley every week every Sunday when the show comes out and guys odd it's been quite a week a little bit of a crazy week in terms of several different things. If you haven't heard the last show, we dropped the epic to fifty with amazing listener roast, and I got to see again, you guys killed it. Very good. Very good actually kill that. Thought it was much. We're super I've still super oppressed them still kind of pausing over that. If you haven't checked out, go back, it's hilarious. And then amongst all this intitial patient for marvel trailers like we're fucking crackheads over here because everyone is a crack at hook it to my vein. Mc you. We had a little celebrity Junkin nerd fun stuff. Pop up during the week before we get to the news. I just want to break this other show. If you follow us on social media, you will have seen photos of Jay muse. None other than Kevin Smith's right hand. Man of Jane silent. Bob Wareing, well, not wearing. But with behind a jock in nerd podcast de shirt draped on he's kind of put it on him. And there was a series of photos. That was amazing. But not only that it gets better listener, we have a new celebrity drop. Oh, check this out this. Is my favorite this Jason mewes for the reasons? Best left between you and your therapists..
"jason mewes" Discussed on WTVN
"Up. You can go in and buy jumper cables seem like seemed like not so much. So we just sort of sat there for a couple minutes going to do what are we gonna do? What are we going to do? And then this big pickup truck pulled in. It was these it was his father and son duo from Pennsylvania who were driving Illinois to go deer hunting. And they they don't have deer in Pennsylvania are not the ones they wanted not like deer. So so thankfully, Tackett. Dear thankfully, to those folks gave a jumping roller merry little way. There is the Jack tell me your tell us your story. Well, if you like deer, you'll love rats. Especially in Columbus. Oregon pest control company Orkan has released the list of top fifty Radhia cities in America. They conducted a survey. Can I say can I say before you get into your survey that orchids the same one that I think put out the survey a couple of weeks a couple of weeks ago, they always put out these surveys of. Get your bedbugs survey, bedbugs, or guess, what your your town didn't fare very. Well, it didn't you better call or can let me guess, of course, let me guess we have a rat issue. What would you think that Oregon's going to conduct a survey on fresh produce? Of course, they're going to do what they know which is rats and vermin and how to get rid of them. Yes. Well, we're we're fair in a little better than some other cities. Okay. Not much, but we are our right? We're not we're not the worst. At least we're not Detroit. Yes. So orchid ranked metro regions by the number of the new road at treatments performed between September fifteenth twenty seventeen in September fifteen twenty eighteen years worth of data. Yes, they decided. Okay. Here's a years worth of data's now. We can say which cities have had have the worst rats. No k for the fourth consecutive year in a row. Chicago was number one. All right, followed by Los Angeles, New York, Washington, DC, San Francisco, Detroit, Philadelphia the first Ohio city on the list at number eight. Do you think it's us? Do you think it's Cleveland, or do you think it's Cincinnati? It's cleveland. Oh, okay. Cleveland at number eight. Yes, go Browns. Baltimore comes at number. Ten number nine. Denver comes in at number ten now. Cincinnati comes in at number twenty in. Columbus comes in at number twenty five. Oh, well, that's not bad. Actually, Dayton, Ohio is the only other Ohio city in the top fifty. They rank at number forty eight which is interesting because Dayton, Ohio is not that far from Cincinnati. However, there is a twenty eight point rat difference. Well, any favorite cities that you want to know about where they are on the list, I have favorite rant. What's your favorite rat Templeton? Oh, Paul Lynde. Will he was? Yeah. Hang Mohi over in Charlotte. Well, he was voiced by Paul Lynde in. Poland wins was from Lima, Ohio. Yes. The only rant ever occupy the center square on Hollywood squares. There you go. Yes. He was from was having wasn't Lima. I'm not sure what are the notable cities are on the list. Well, Houston is number twenty three. Okay. Pittsburgh, our neighbors were the deer aren't very good. Yeah. Is that it's number nineteen. Let's see here. Rochester, New York, number forty five Orlando's number forty one. Yeah. So the the mouse have a lotta rats. Okay. So that's kinda nice. Yeah. Phoenix. Really hot city Phoenix. Yeah. That's at number forty and I'm trying to see here Las Vegas, mid the list. No Vegas is not in the top fifty copy that. So there you go there you so if you wanna if you want to know more about rats, go for more on ran, they'll tell you. We'll tell you how how they don't kill them. This story out of New York from last night Aerosmith guitarist, Joe Perry reportedly taken to the hospital after he performed with Billy Joel at Madison Square Garden in New York TMZ reported that according I witnesses the musician went back to his dressing room. They he and Billy Joel had done walk this way. And then. When. Joe Perry backup on for the longest time. Now, Joe Perry then goes back stage and collapses in his dressing room, sheer embarrassment. They put a tracheal tube down his throat to clear the air path people were panicked. They said he did not look good. Perry who is sixty eight was taken out of Madison Square Garden on a stretcher into the hospital reports today say that he is alert in anxious to go home. Oh, yeah. Who was an anxious to go home, and they're from ability Joel concert. I like Billy Joel, by the way, I have a theory though, I think Joe Joe Perry, of course, from from Boston. And and and Billy Joel is from New York City. I think you know, obviously Red Sox fan Janke fan and. I was just trying to illuminate one of them right there. It's a big rivalry. That is sinister. Yeah. And believable. Yeah. No. It is. I actually that's not the craziest theory. I would have come up with. Yeah. Going on around Columbus this week on Tuesday night over at the funny bone Jason mewes, Jason mewes. Yeah. Yeah. Jay, Jay and silent. Bob, Jason mewes in his amusing stories, I guess it's going to be nice of him just telling tales Thursday night. The blue jackets will host the Florida Panthers over nationwide. Comedian Christopher Titus at the funny bone Friday, Saturday and Sunday nights good band gusto at the Newport, Saturday night, and then her excuse me. They are good band. I just haven't heard anything from gusty like twenty years long me talk about okay? Fair.
"jason mewes" Discussed on We Hate Movies
"My head erupted. All right kids. We're just gonna to watch Netflix for the. But this I was on the cats. I just found our. Maybe our let's Domino's just relax for bit. Anybody got cigarettes? Okay. This kid is Steven Anthony Lawrence also shit like cheaper. By the dozen the will Ferrell kicking screaming bubble. Boy, you gotta data birth. Nineteen ninety. He's he's definitely legal that will make fun of our God. Get your head out of the gutter kid trafficking. Oh, yeah. That's twenty eight. Now. He's twenty eight. He's twenty eight good for him. So moving on they find the dog or whatever. But Alec Baldwin gets the dog. This is when Mike Myers needs to do a stone her joke, that's one way to call this. Yes, it's him dreads. And he's like, oh, you know, who wants to save the fake charity or something because it's fucking two thousand and three George Bush is in power and charity is a Larry. It's a thing where he's so they're like listen, we need to distract Alec Baldwin long enough that we can get him to like give up the dog or whatever we'll like run away with the dog. So this is what he's he's it's supposed to be like a white guy with dreads like college activists by getting petitions to save the whatever. Animal. It's like some fake thing. Oh, that's right. Yeah. And he says something about like, oh, blah, blah, blah. And that's your dog there. And the dog is like keep me out of. That's right. Oh god. He turns the camera and he goes oh sorry. I meant canine American what the fuck are you talking about? That's not a joke. It was not even remotely close to being funny. Andrew, I don't know if you're aware of this. The PC culture has gone mad. I heard some rumblings. But I did not want to admit it. Can't you believe you can't even say dog any ward, gosh, dirt Barucha? Ted Nugent would say stranglehold on we're bringing it back folks bringing Doug back Roseo. Dan looks like. See Doug is back. Brozi looks like a canine American. There's I could turn it down for a little bit as if you nice to meet it'll be nice to you. So you're supposed to be signing the immigration. There's a thing around here that I don't quite understand. There's a secret entrance to a nightclub that you get to through a port of the fly in fuck is this. I remember walk through a shitter to get into this nightclub. Yes. It makes sense because Perez Hilton's inside. This was was on the white board of like things we should include because it's the cat in the hat movie. Right. That had is pretty big rave culture. Like, you know, what I mean like? The only thing I thought was like Austin powers does a lot of dancing under lights like that movies. Maybe it's called back to that. God. But he's also he wants to fuck parasail. Yes. Absolutely does is heck goes up. She exists in Dr Seuss, the cat and. Very interests. She's in this movie because it is too dated precisely a movie shot in two thousand release in two thousand the world at large still gave a shit about what this house of wax house of wax. It's very cathartic to watch. Do. She gets a fucking poll through the head and the hottie and the nutty Addicott in the novel was a little bit later that was like a really that's got for this movie the last that was the last ditch effort absolute being romanced by Jason mewes film. Oh, yes. That sounds no of the time of pulling the head. What was what movie was at the house of wax remake her sex tape? Gotcha two thousand three. I did I should say I did parents on fear baiting about that movie. It will be up at some point. He's a podcast you best years. No, no, no, no, no, no kids. Chris Kevin is watching the movie fear and jerking. It is a movie called the bottoms up. Oh with a year. What year do this sounds like a real fanny comedy two thousand six it's eighty nine minutes long. Younger than this. It's got Jason mewes as the lead Paris Hilton. Is he playing snoot master general? He's bigger other. Mcnasty? Oh, you better. You'd better believe Kevin's visit playing rusty number two. Yeah. There's probably a joke in the Kevin Smith is rusty trombone. So like dancing around there is a dance number year. Kind of he loses his hat..
"jason mewes" Discussed on Hollywood Babble-On
"I was there. I remember has multiplex theater near us that was playing the flick, and we signed posters in the cast Brian and Jeff, and Maryland, and Lisa and Jason mewes wasn't there because he wasn't aware that it was a movie yet. He knew each shot something, but he didn't follow that closely. I kept telling him, I'm like, it's coming out. He's like, I'm not on the poster and so he wasn't that keyed in. He's not. If you look at the clerk's poster, he's not. There is not represented show up that day, or was it just say said, well, they said when we wanted to poster shoot, it was, you know, of course the two boys, Brian, Jeff, and the two girls, these Maryland and I was there. And I soon Jay would be there, but they were like, we don't want Jay, and I was like, why? And they're like, well, the movie's called clerks. It's not about the guys outside. It's about the guys in the store, and I was like, what am I doing here? You're the director. So on the poster is the director. If you look at me on the poster, I'm not only think I'm wearing a hat. You're not bobbed out at all? No, and Jason's not there with me. So they were like, you just look like a gen xer standing. So extra your own poster much. So. So strange. So we all signed posters and shit like that. And people on the flick locally. It was cool and it played at the Anjelica film center. It's like one of the theaters opening. In fact, I'm wrong about the has multiplex that was one month later. It started only a couple of theaters in New York. It was the Andjelka foam center and in Los Angeles, it was the Lumley sunset five one screen on each coast. And I remember we had like a sixty thousand dollar weekend. It had made thirty thousand screen and everyone's like, ooh, that's a good. You opened on into theaters clerks, never played on more than fifty screens total at its biggest. It was never on more than fifty screens. A real like art house release was small when it went to video. That's where most of the audience found it, and they didn't know that like, oh, this played only an art houses for most people finding on video like this never played anywhere. You know, they never thought at their multiplex same with Marat's. I got a lot of movies but never play anywhere near anybody who. What am I all? Two movies set in Canada. Never played up here. I know. Yeah, fucking strange. But yeah, man, that was twenty four years ago today. Everything that has happened since including like being able to come up here to Babylon and stuff comes pretty much from that moment. Right there. Sure does. Yeah, because we speaking of which I know you have a super fan here tonight. I do man like before I looked on Twitter and it was a guy. Nate. Are you here where the guy who's dressed exactly like you that guy. I mean, you could say that a lot of your fans out man. Come on. So. Was putting pictures up on Twitter, glad to Pat you down for weapons, sir. Before you come up here. All right. Now trust you, you know, just where to look. He was putting up pictures of all the stuff that he's bought and it looks like a fairly complete collection. Did you even have Dougal fucking cartoon where I played the part of the moose. Of that for some copies of Dougal you bought both of them. I haven't room in my host, looks rows, Batman room. He's got to collect, he's got a cave, has my wife doesn't even let me put my own shit up man..
"jason mewes" Discussed on Hollywood Babble-On
"Oh, that fuck it. Rocks girl Sangley. They went off into the whole. It was an amazing. Oh, that's awesome. He's living life, right. How does that fucking kid man forever a A memory. memory. Sherry builds a career. It's all downhill from here. Start doing smack fuck, and it's all over case the dragon because it's all done for you. Kid know, you'll never be as good as that. He's the next slash. It's got lose his virginity really realize that all. Play with Dave pro ten. This is matter. The me. Get out of my house Brenda for Brenda feel. I love you more than those twenty thousand. Fuck just range. Earth. Gene, we're don't. You. From the best in entertainment, like Dave Grohl, we now go to the worst. Nobody. I'll tell you why. I think I got spit in my audience on that one. Well, done. Justin Bieber teach just such a fuck and tease he says, I'm leaving the country. I'm going back to Canada, just bought a big piece of property and candidate goodbye America done with you. I don't wanna deal with you anymore. I want my privacy. I'm going to Canada. And then he put down roots in the San Fernando Valley in California this week, he would have to name married to that girl. Now, sort of bad girl away. She's on a TV show in Los Angeles, Haley, Haley Baldwin's on a TV show, I believe is host of drop the pass the mic. Drop the mic. Drop the mic. Yes, co host of drop the Matz drop the mic. It's a show that me and Jason mewes are going to be on a couple of weeks. It's basically a rap battle. Okay. All right. So they sent us lyrics where we badly other. Pretty mean. Like you share, you say this shit to you on TV. He was like, do it. But she's the host on the show. That's how I know her name. So I assume he would have to be here. They are renting a home on the lake there in the San Fernando Valley, it's six thousand square foot home, apparently fucking huge. That's pretty big. You know what they're paying per month. If first of all this stories, Greg, because he doesn't want to spend a lot of money and buy a place just renting our way to second six thousand square feet San Fernando Valley per.
"jason mewes" Discussed on Hollywood Babble-On
"That'd be birthday Taba. You can have one of these batmobiles for your birthday. Okay. Dabo gets that Moby. Oprah Winfrey of this coming towards just some random guys gonna cash in on top bows birthday. He goes sir happy. Did you like sixties, Batman, God bless you for lying. Even tell you, you don't look, thirty five, don't. You're dreaming. You're not. Stephen l. dreamy but you're dreaming. They showed a, they showed a clip reel of the upcoming seven season marrow and he's in prison. Now, he's a minute. He's green arrow, and the FBI has put him into prison for life in exchange was last season. The last episode like months ago. You can't come the kamikaze. Dealers bad. DVR will watch a fucking show once in a while. You lazy prick. You know that's meant to play the shows to collect them, hoarding them. Forty two. So he's imprisoned now and all he does is like workout in his cell shirtless and is a lot of showering scenes with him. Another buff, dude, it's like it's like they have a female show runner this year. It's very obvious. They're just all about just all about Stephen melons fucking ads. He I remember the first time I was exposed to the show. Jason mewes was big fan and he was just like he has an ipad occurs. Watch his shows on. He's you. Gotta see, fucking ERO, man, that's doing green arrow and shit. Look. This shit here is looking book and green arrow, and he showed me a scene of Stephen Mel shirtless doing the salmon ladder exercise, like where you're doing chin ups with your whole fucking body, move. The bar runs the bar up. It's impossible. It's like something I watch, and I was like, wow, they do a great job was special effects on that show because no human. We'll do this and shed Jay's was like, no, that's a really human being and shit. And I was like, what the fuck man like, what does this have to do with fucking green arrow and shit? And he goes, oh, you want to see him shoot a fucking ERO and he shows me seeing of Stephen Mel shooting and aero again shirtless and I said to Jason, I think you like this show for reasons you don't understand. Speaking of being in great shape is Randy Saldivar here. Sure is your is Randy writes, first time show attendee regular listener to the podcast. I may strength and conditioning instructor for.
Daniel Clark, Jay and Bob discussed on Z Morning Zoo
"Morning zoo presents celebrity dirt so i used to watch american horror story religiously watch every episode of the first five seasons and if i had to pick my two favorites would be murder house in covent low murder house was the very first season was career force which whatever it's hurt get really weird like roanoke and cult those were just they were just really weird yeah just trying to hide while i'm guessing producers finally realized that it was starting to get so seki so now they're doing a crossover season this upcoming season between a murder house and then really really looking forward to this sort of like it then you hate it you might love it again so i'm definitely going to give this one tribe drake's new video or i'm upset is a massive degrassi high school reunion now remember that was the show he was on the canadian team and he got tons of former co stars to appear in the video it came together in about a week they got a bunch of people in it even no kevin smith jason mewes there jay and silent bob characters did some episodes in two thousand five but one former co star who didn't make the cut was daniel clark and he was a little sad music video and so i was like in a state of shock i was like whoa a lot of people knew about it it was just really strange that i never heard from anyone can get the phone get the phone call how'd you suck on that show or what did you do to drake as cold everybody know when you mentioned jay and silent bob they were only mean a couple episodes make this guy was in the whole show and they didn't call him was he the guy who shot jimmy jerry wheelchair yeah you would think nah yeah something had to have happened hoops coming up in the next after twenty six seasons and four thousand episodes one of your favorite shows is ending dirty looks never seen you adjust it's special occasion not in glad i made it john big time again wait.
"jason mewes" Discussed on Hollywood Babble-On
"Lethal weapon the hit show on fox almost cancelled because clean crawford not a real fucking name by the way clain seal a y n e not a lane it's alliterative name like like peter parker were laying respect or clinton made that up his name's john crawford by the way you should not claim is made up yes so fuck this guy first of all they get fired for that should've claim burgum into the office at warner brothers like i'm sorry come to our attention did you make this name it's not a real name he damon wayans play buddy cops on the show you know the story lethal weapon jason mewes loves the show and he was very upset when they fire this guy he's like he's so good on the show here tough guy to work with and he goes you might be worth it it got so bad between the two of them they had to hire private security stay between them at all time so they winker and security yeah for real there was half half the crew apparently was back in one guy half back the other it was like a war on that set here is a video of the two of them talking before they went into action on the scene there sitting in a car i guess in this scene and they're wired up and they're talking to each other and they're referring to an incident that had happened onset earlier we're claimed crawford was directing an episode right and damon wayans got hit with some shrapnel cut him in the head and i guess he went and said something or complained or something because that's what he refers to the damon wayans isn't necessarily sure that it was shrapnel the 'cause the cut on his head he is said to many parties it was weird that the explosion was on this side he got cut on this side he thinks maybe claimed crawford decked him or hit him with something or clip them or something what's yeah he thought maybe took a shot at some point during the action sequence should so they are talking about that at this point and it gets well kid starts bed and then gets worse.
"jason mewes" Discussed on That Awful Sound
"They're terrible maybe maybe you should stick to your name and be the muse for some other band exactly he's not making music he likes muse because he heard them before heared radiohead he likes muse because he's a big fan of jay and silent bob and he thinks that's jason mewes band okay so let's get back to our regularly scheduled programing here unwritten law was formed in poetry california in nineteen ninety original drummer wade young men human human human just totally normal human wade human generally takes credit for starting the band very funny sentence i i generally take credit for starting the band sometimes other people take credit for it but it's mostly me really know why you'd want to but because he got kicked out he's one of the four people who got into a fight with the lead singer at different times throughout their careers and got kicked out of the band i have i have that right here actually oh no this is this is the guitarist who got kicked out the weekend prior to the anaheim gig the band plan to perform this from mtv dot com the bla the band plan to perform f i t which stands for fight from it's latest disc it's an odd way to refer to an album here's to the mourning quote kids have been coming up stage asking for that song russo said because they want to sing along it's just can't stop rhyming this guy's such lyricist so we practiced the song during that weekend and when it came down to the day the show rob was prepared to do the song but we already committed to that song we said we were going to be playing it.
"jason mewes" Discussed on /Film Daily
"I was i was just as prizes you were about this because nothing against account it's an entertaining movie but i was not expecting this to be the number one digital rental of two thousand seventeen but it was the runners up where disney's milana and wonder woman so people are really into renting the accountant for some reason see mwana in wonder woman makes sense to me they count into nine i've seen they can you have to is hugh seen the camp i i have not seen i i have no interest in watching it sorry to say to all those people who rented it digitally better catch up there making a sequel you don't wanna be left at the loop you know it actually surprisingly fun film i'm not gonna say good foam like i i never knew i wanted to see ben affleck is the counting superhero but that that's what the movie is and i'm just so strange because i feel like if i was prompted with a list of movies on my like you know apple tv or however people rent movies nowadays like a movie called the accountant sounds like the most boring movie i mean the movie isn't that but it's just so strange anyway let's move on to jay and silent bob they are coming back ht where we're going to see them we're going to see them in virtual reality so jane silent bob are striking back in a live action comedy series written and directed by kevin smith who stars also as silent bob and it will be shot from the point of view of smith silent bob character as jason mewes jay quote leads the way through a string of idiotic adventures and quote so it sounds like a classic jay and silent bob movie and kind of the next step in addition through indie movies through cameos and kevin smith movies comic books and even a video game so vr i guess was the only sort of terrain that they haven't explored yet and it's part of one of several vr projects that's been announced in development by s entertainment surreal division.
"jason mewes" Discussed on Hollywood Babble-On
"Anyway there it is man happy to be here happy well these people are happy to have no more so than me though my friend i know ralph was insanely wonderful stop by the hospital house and stuff like that yeah you were buddy i'm telling you lot of people fuck like i don't think i've ever seen jason mewes more concern maybe because he was just like j n doesn't work so but like that he too was like more rattled by this than than i was i'm telling everybody around me was was way more rattle than stuff i i'm from my end it was kind of easy like you know i'd love to beat the fuck and widowmaker because only eighty percent of people get that clog is walk away from generally speaking by even do that shit was the doctor just laid they're asking a lot of fucking questions trying to cover my dick so like so you know it was weird is going on in adventure you didn't plan and like one that scared everybody else and then you're like oh but i'm fine i'm fine so ralph was super fucking good sern but yeah i'm fine i'm doing great all right yeah let's talk about anal sex and boy ses things mentioned we we did have to postpone some shows on the road until we got a an you're right let's see you're growing grind i would have to pull part so many layers of roles of chop to notice shy that's very small that's the other thing too man it's not like look at my fucking manley scar the scar for where they went up my groin tamar very small like my dick very but it's very tiny incision it wasn't like they don't record or anything like that.