37 Burst results for "Infection"
Fresh "Infection" from News, Traffic and Weather
"24 hour News Station Co. Moh news 1000 FM 97 7, There is evidence of a new covert variant spreading rapidly in New York City A B C's with Johnson reports, researchers arguing this could be yet another variant of concern like the UK, South African and Brazilian variance. We really need to accelerate our rate of vaccination. It's all hands on deck. Try to get the American people vaccinated some of the variance raising questions about the impact on vaccines. Fizer announcing They're talking to regulators about testing their own variant, specific booster, offering a third dose to 144 clinical trial participants. Madonna taking similar action, sending modified vaccines for the South African variant. The NIH for testing, including a combination formula for those getting their first shots should that become necessary and there is new hope on the horizon. Johnson and Johnson on the verge of adding a third vaccine in the U. S. This one shown to be effective against the variance. The vaccine provides very robust protection throughout the world. Including against the worrisome Bible, very ins that we've been hearing so much about new data showing Johnson and Johnson's one shot vaccine maybe 100% effective at preventing hospitalization and death and early analysis, hinting it may offer 70% protection against asymptomatic infections, making those vaccinated less likely to spread the disease. The FDA meeting tomorrow and could give emergency use authorization as early as Friday night. If the change a vaccine is approved, it will.
Will vaccines make a difference responding to the next outbreak?
"I'm health reported teigen tyler and physician in journalists alter norman swan. It's the last corona cast of summer fridays. twenty-six yes. We are on the last current cost of summer. And i feel like i am. Maybe potentially jinxing us by talking about an outbreak. But let's talk about the scenario norman. Where if there was another outbreak in australia. Now that we've got vaccine in the country vaccine which we know is quite effective at preventing disease and infection. Would that change the way. We've been responding to outbreaks in the past year. Yes would and in fact. I think we were probably the first out. Let's talk about. It was called ring vaccination. And it's now part as far as i understand it over the national immunization or vaccinations strategy. So what you do is as you do your contact tracing you would ring-fence vaccination around the person who's got the disease and the people that have come in contact with and maybe even the people that they've come in contact with so primary contacts and secondary contacts and you would do that with the pfizer vaccine because you've got a strong response early and is only three weeks between doses so within three weeks you're fully immunized rather than the astro which might take twelve weeks to get up to that sort of level of antibody response and so a and it's a race against time so that you because the incubation periods five to eight days but what some of the research is showing is that you get an early response to particularly the pfizer vaccine. Maybe even the astro too so you get a pretty good resistance there early on so that would be a good way to respond to outbreaks prior to very large percentage of the population being covered. So when you vaccinate sometimes depending on the disease some vaccines take a couple of weeks before you get an immune response. But then there's other vaccines like rabies. Where if you get bitten and you think that there's a chance got exposed to rabies. They give you a vaccine then. Do we know what the fires a shot does. Whether it's the sort of vaccine that you can give after exposure and give you some protection while it is all about the maths which is the incubation period versus the time for the vaccine to work so smallpox that's how they controlled. Smallpox control smallpox by massimo. Certainly helped but in places such as africa they controlled it by ringfencing and controlling the spread from that and so they find they find a case a main they ring vaccinated around the person with smallpox. So that in for anybody who might have contact come in contact with that person was protected and in that case the vaccine for for the smallpox vaccine worked faster than the incubation period of smallpox. In this case it's lying ball but it's worth doing because it's likely that you would get a responsibility and you're doing two things by this ring. Fencing are ring vaccination. I should call it. You are protecting somebody against severe covid. Nineteen disease the second thing you'd be doing is trying to prevent transmission and you'd hope those two things go hand in hand is a bit of evidence from israel that they do but it's not strong
Fresh "Infection" from Ground Zero with Clyde Lewis
"Abroad Boulevard blocking your left lane. I'm Ricky Riso News Radio 6 10 W y o D. I got a few files of the forecast and temperatures in the Middle Ages this afternoon, so little warmer than yesterday. Without the rainfall Tonight some clouds of warm 70 Friday. Clouds and sunshine 82 weekend looks good Lots of sunshine. Low eighties morning lows coming up into the mid seventies with updates around the clock. I'm South Korea's severe weather station on the weather Channel three stages on NewsRadio. 6 10 Wi OD. Publix is opening up its online reservation system for vaccination appointments at all 730 of its in store. Florida pharmacies appointment scheduling starts at 7 A.m.. Only those 65 older will be eligible to make an appointment. Florida health officials reporting 6600 New Covad 19 infections Thursday and 138 recent deaths. 16,000 Floridians filed for first time jobless benefits last week, the lowest number since the pandemic began. Almost a year ago, The state Supreme.
A third Pfizer dose? The Covid-19 vaccine maker is studying booster shots.
"Effectiveness it preventing Corona virus infection after two doses of its vaccine visor is now seeing what a third dose might do. The company announced today that a booster dose is being studied among people who received their first doses of the vaccine more than six months ago. You're not
Pfizer's vaccine trial data holds up in the real world
"More again on the pandemic and the promising news about vaccines that Seems to continue to pile up of late. We're joined now by Dr Amos, a doll jah, senior scholar at the Johns Hopkins Center for Health Security and a professor of the Johns Hopkins Bloomberg School of Public Health. It's always good to get your insights doctor and I want to get your take on this latest study out of Israel that seems to verify the clinical data we got on the Fizer vaccine that it seems to be Just about a super effective in the real world as it is in lab settings. What do you make of this pure reviewed study? This is great news because we always know that it's one thing when you're in a clinical trial, and you've got a lot of protocols and certain people who volunteer for those clinical trials, and then you move from that setting to the real world where things can be a little bit more messy. Are there a lot of variables that might not have been accounted for in the clinical trial, and that's what we really understand how effective the vaccine is moving from F ethical efficacy Studies to Real world Effective ists. I think this is good news, and it really cemented the fact that these vaccines are the passport and the way we get our lives back and put this pandemic to rest doesn't make you think that vaccines could get us to herd immunity that it'll be vaccines alone. That could get us to that step that we all want to see. Do you think that vaccines will eventually get us to herd immunity? But it won't be vaccines alone because already one third of the population in the U. S likely has some level of immunity from prior infection. Herd immunity, although it's a major milestone to reach. It's not the only thing I think to me the biggest The biggest milestone would be vaccinating are vulnerable populations completely so that this virus can never cause serious illness, hospitalization or death again that it could never threaten hospital capacity. I think we were will get there first. And then eventually herd immunity will will come. So I think the key is really taming this virus, making an unable to cause serious disease. And that's why our vaccine allocation process is geared towards those who are most likely to have severe disease. And I think we'll get there first. Before we hit hurted me. Did he speak about vulnerable populations? Doctor? I wonder if you're also thinking about the racial disparity that we continue to see in the vaccine distribution effort we saw Further evidence of that on the Bloomberg vaccine tracker just yesterday. What's it going to take to sort of bridge the gap between black populations receiving the vaccine and white populations? It's going to be very, very challenging. And I think that The more people that get back stated. The more people in those communities that are vaccine hesitant or afraid to get back there because they're on trusting of the of the vaccine or public health authorities. The more they see people get vaccinated and nothing untoward happened. I think the better it is. But I do think we need specific outreach to those programs to those individuals specific programs that really trying address their concerns almost on individual basis, because if that group does not get back stated they still represent they represent some of the people that are most risk for. Of your disease. They're disproportionately the ones who've died from this. We have to do better in order to put this pandemic to an end. And I think it's going to be challenging. And I think we're gonna need the innovative solutions. We're going to the community leaders to really Show people the data and be very transparent about how effective these vaccines have been in go through all of the safety data and hopefully persuade them to get vaccinated at much higher rates than they have been. Our last minute here. What's your level of concern about some of the latest variants we're seeing reports on with there's a New York Times report just this morning about a variant in New York City that seems to be spreading pretty rapidly and could blunt the effectiveness of vaccines. Yeah, it's hard to know exactly how to take all the news of the variance. We know that this virus has been making variants as soon as it jumped into humans and most very instead from made headlines have never made The New York Times Because they didn't change the way the virus behave. But there are some that appeared to have made the virus more contagious. Some that have Changed the way the virus interacts with the immune system and those air more concerning, But I do think when you look at our vaccine data against these areas, including ones that are more Troublesome like the one that they call the South African variant of the resilient variant. The vaccine's still do remarkably well on what matters. Preventing severe illness, hospitalization and death. So I do think that the goal when it comes to these variants is to stay ahead of them by accelerating vaccination programs to the fastest possibles rate. Some of these various don't pose a problem, but I think we need to do better attracting them and understanding them. But not everyone that you see is going to rise to prominence and I think we're getting better now at tracking them. Sequencing, and so you're going to hear more about various, but not all of them are going to be of the same important that it's gonna take some time. Specifically all of that.
Johnson & Johnson COVID-19 vaccine deemed "safe and effective" by the FDA
"And johnson. It's been shown that they're vaccine is effective at preventing hospitalizations and severe effects of covid. Nineteen this from scientists at the fda we're seeing about. I think it's sixty six percent effective when it comes to moderate to severe cases of covid nineteen so matthew. Tell a little bit more about what we're hearing with. His johnson and johnson vaccine right so what happened. Is that johnson. Johnson released data about a month ago. You know press release but the process for evaluating these vaccines is that they go through the fda and the fda really unique in the world independently looks at the data and re analyzes the data that the company produces and its own report and then hold a public meeting which will be happening friday and so the documents before the public meeting came out and they had some good news both some really clear data on hospitalizations and a general sense of approval from the fda researchers. Sometimes they're not as positive so it looks like this may be another option now. The big plus is on. This is one. It's a one shot dose. So you don't have to go back for a second jab in the arm and also doesn't need to be kept frozen like the pfizer derna vaccines do so shipping and handling of all of this will be a lot easier much easier to transport and that's a big advantage. It does not look like we're gonna have a huge amount of supply the start off with so it doesn't dramatically change how fast we're going to be any shots into people's arms but for a lot of people i think in a lot of experts i talked. You think this'll be a great option. It's one and done. I think some of the numbers. I saw the might have about four. That are produced right now. Ready to send out so it gets approved. They can get those out really quick but it wouldn't be until april possibly where they can really ramp up production to start distributing that right and will also be getting over that where they're hundreds of millions of doses of the two vaccines have the madonna and fayza biontech vaccines. That are expected to arrive in the us by july. So there's gonna be a lot more vaccine available. The jj supply will ramp up and we'll be getting more of those other two vaccines that leaves. There's a vaccine coming from nova vacs. We don't really know about how much will getting the early results issued press. Release again good and we're waiting for. Us results on the astra zeneca vaccine. Now some good news. With his johnson and johnson one is its effectiveness against these variants. That we've been hearing a lot about so it fared better than expected when it comes to those. I the way to interpret. That is we'd seen some results and the new results that they showed today look a bit better than what we'd seen in terms of variants. There's still does seem to be decreased. Efficacy against the south africa variant. Three five. Which is really the one that we're all worried about but it did look better than what we've seen previously and what j. j. has said it seems like with those variants. This vaccine is still preventing severe disease and hospitalization. Which are the key things. We've always wanted from vaccine here. The idea that you'd prevent a symptomatic infection or mild cases kind of bonus compared to just making sure that people end up in the hospital hospitalizations numbers were good on that front. What did we see when it comes to side effects. I saw that there were a few unexpected side effects. Although these are very rare you know but The expecting side effects the kind of pain in the arm the headache fatigue. That's pretty much in line with the other two vaccines. We have that right now. There were some rare events that occurred more often in the vaccine in the placebo group. Keeping in mind that forty thousand people were in this trial. There were fifteen serious blood clots including some. Dvd's in that exciting compared to ten in the placebo group. That's something the fda plans to monitor there was also some rini ears in the vaccine group and not in the placebo group. So that's kind of an odd one that will wanna watch again. This is really a prelude to friday win. Some of the top experts in the world are going to gather on zoom call and go over these data that the fda assembled we'll be live blogging that stat. That's when we really find out a lot about any medical product. It's it's one of the amazing things. The fda does now an interesting thing in all of this so public health officials might have a messaging problem when it comes to pumping the johnson and johnson. One out when we're seeing guys like pfizer maderna's say that their vaccine is ninety five percent effective against corona virus. Just listening to numbers right. This says sixty six percent. So what are they going to have a challenge in getting people to want to take this one over the other or you know how how to work out. It's really important to realize that particularly between those three vaccines. The getting vaccine is much better than not getting a vaccine. The change vaccine may be on par after a second dose and that study is being done but unlike visor during the second dose is going to be months after the first and then also slows down the study. She gotta wait right for people to get their second dose. So we're not expecting those data until kinda summerish but the big thing is for a lot of people. There was also the appeal of a single dose here. And i don't think we should understate that. And the effect on severe disease is big so the problem is gonna be the in the initial rollout. You really want people to take whatever vaccine. They're giving because being vaccinated is so much better than not being vaccinated. And that is part of the path to get in the world back to normal and public health. Authorities are absolutely going to have to articulate that now again because there's not going to be that much supply of this initially. They're going to have time for a learning curve right now. the demand for vaccines clearly outstrips supply. That's why you're hearing so many stories of people desperately logging on trying to get vaccine. What scott gottlieb used to run. The fda has raised the issue of you know. We're we're going to reach a point where the people who wanna get vaccinated we'll have been vaccinated and we're still going to need to vaccinate more people and that's when convincing people who are less sure to take vaccine in to take the vaccine that's available is going to become more of an issue last question briefly pfizer moderna vaccines are based on 'em a. What kind of platform is the johnson and johnson. When using this like theatrics annika vaccine is called an ad no virus which is a kind of virus that is used to the same kind of ideas marin a the instead of traditional vaccines were you inject the protein that your immune system sees and then learn to recognize an attack. These sneak something into your body that makes a lot of proteins. You make a lot more protein and then the body recognizes that an attack it in this case they're using this virus which is kind of a cold virus to sneak some genetic material in and that makes the spike protein from the sars virus which your body then learns to recognize and thereby has antibodies that attack the virus
Johnson & Johnson's single-dose vaccine is effective
"And just a matter of days, FDA staff says the single dose Johnson and Johnson vaccine is safe, even if it isn't quite as effective in preventing infections as the Fizer and Madonna vaccines. Still, governor to Santa says it will prevent all hospitalizations and deaths. And he says that's a win. Says officials are still trying to decide exactly
What we know about Tiger Woods' crash, condition and what happens next
"Thank you so much for joining me tonight hush. I wasn't pablo so ramona. You have just spent many hours right outside. The hospital where tiger woods is being treated. What was the scene like where you word it you know. It's it's weird you go stand outside. Hospital in the middle of a pandemic is a lot of stuff going on right. And there's a lot of news trucks helicopters everywhere. You know mostly news helicopters hitting a lot of a lot of reporters but i was just. I was out of the hospital. But i was mostly just working the phones all day. And it's you know it's pretty sickening. Pablo it's know as a reporter you you go and you cover something like this and each one of them kinda hits you right because it it speaks to the fragility of it. I'm i'll tell you one man who was a locally said you know he knows somebody who died on that road in that same spot similar area when a coyote jumped out in front of their car swerved and he was just a really dangerous patch road so ramone. I want a time stamp this for the listener right now because it is ten twenty one. Pm eastern time is therefore seven twenty one pm out where you are in l. a. What's the latest right now. What's the latest information that you've received from authorities from medical sources from anyone from tigers camp. Well you know. Tigers camps dot pocket a lot more than the initial statement. But what my understanding was that he had he had his some of his camp was with him. And when i was. When i was there at the hospital just just an hour ago which would have been about. Six o'clock i think is when i left pacific time. My understanding is he was still there. He was either still in surgery or just finished. You know it's kind of hard to get a minute by minute. There's nobody coming outside the update the reporters kinda have to be be be working phone to get information and you know they. They you know the people. I had spoken to said the most important thing. Is that you stabilize these injuries. And you wouldn't wanna move somebody to another hospital. How if they moved them. They'd probably move him to ucla westwood. Which is another world class hospital. And that's probably a little easier to control the scene there. He probably get a private room there. You could probably if he's going to be there for a long time. And and i think this is going to be a a a lengthy stay in the hospital This is the kind of thing that you've gotta you've got to take your time and and You wanna be comfortable and it probably going to be multiple surgeries So to me it's a really it's it's this is going to be unfolding over the next few days and weeks not hours so on those surgeries and about what's required year. It has been reported ramona. That there's a compound leg fracture a shattered ankle. But what do you know. What's the latest about tigers medical status. How serious is all of this. He he he has. He basically had crush injuries. That's putting you you look at the car k. Cars crushed the front of the car so his legs were in the front of the car. one of them is a is a basically shattered ankle. It's the tallus bone. The other is the is a compound fracture of the fibula tibia Sorry that's shinbone. Basically but there's also a vascular component and that's your circulation. That's your that's just your blood vessels that had been really severely impacted the nerves. That's actually a little more dangerous even more dangerous part of this of these injuries that they have to stabilize first before they ever even think about. Okay let's get him walk in or anything like that you just. You've gotta get him stable. It's very it's a very dangerous thing. And then there's then there's issues post up post operative complications of leeson's like this if it's if that was actually open i don't i don't know if it was open i've heard that but we'll wait for the official medical On that but if it was opened infection issues blood clot. There's a lot of post operative conditions that you'd have to look at and work on. And i think that's you know everybody i've talked to whether it's you know in the gulf war all the medical world just in l. a. Because everybody in la is is talking about this today. It's all just concerned for tiger woods. The man not tiger woods golfer as for the
Apple users targeted by 'mysterious' malware
"At both Intel and new M one based Max called Silver Sparrow. It's been detected on almost 30,000 Max. So far, those mashable reports there's no evidence of a harmful payloads of security experts can't pinpoint the malware motives. Security firm Red Canary first discovered the Silver Sparrow and it's been spotted in 153 countries. As for how it arrives, it comes by way of an installer disguised as a legitimate application or an update. With the generic name update, ER or update It's unusual for malware to Target Max and to have to type a minute existing Intel based Max and the New Apple silicone powered and one Max is even more rare. And Apple spokesperson tells me Apple revoked the developer accounts needed to authorize installation to prevent new infections and reminded users the Mac APP store is the safest place to get MAC software, though the Apple notary Service will protect users from acquired outside the APP store Fox on Tech, Brett Larson, Fox News. Our
Prince Philip has infection, will stay in hospital
"Britain's Prince Philip is said to be comfortable in the hospital, where he is being treated for an infection. The 99 year old husband of Queen Elizabeth was admitted last week when the palace reported he wasn't feeling
Prince Philip 'responding to treatment' in London hospital for an infection
"And Penny's Saint Martin. Press. Duke of Edinburgh has been in a London hospital for a week now and it appears he'll be there a while longer. Correspondent Vicki Barker reports from London. Buckingham Palace says 99 year old Prince Philip is comfortable and responding to treatment for an infection in the London hospital. Members of the royal family have continued with their royal duties. Prince Charles visited his father over the
Prince Philip 'responding to treatment' in London hospital for an infection
"Impeach him if he doesn't reside. The Duke of Edinburgh has been in a London hospital for a week and it now appears he'll be there a while longer. CBS news correspondent Vicki Barker reports from London. Buckingham Palace says 99 year old Prince Philip is comfortable and responding to treatment for an infection in the London hospital, members of the royal family have continued with their royal duties. Prince Charles visited his father over the weekend, The Duke
Buckingham Palace: Prince Philip has infection, will stay in hospital
"Britain's Prince Philip apparently is being treated for an infection. Buckingham Palace made the revelation today, saying the prince Will remain hospitalized for the next several days. He was admitted to the hospital last week of the time, the palace said. It was just a precautionary thing. Queen Elizabeth's husband of 74 years the prince is
Prince Philip 'responding to treatment' in London hospital for an infection
"Buckingham Palace is Prince Philip is comfortable in a London hospital where he's being treated for an infection, the palace says today. The 99 year old husband of Queen Elizabeth, the second is responding to treatment but is expected to stay in the hospital for several days. Well, Philip and the 94 year old queen got their covert 19 vaccinations in
Palace: Prince Philip has infection, will stay in hospital
"Britain's prince Philip Haas a type of infection I will stay in hospital for now Buckingham Palace says Philip the queen's ninety nine year old husband is comfortable and responding to treatment but he's not expected to leave hospital for several days he was admitted to the private King Edward seven a week ago often feeling ill while officials have called it a precautionary measure Philip's youngest son Prince Edward has told British broadcaster Sky News this is father is now a lot better Philip who retired from public duties in twenty seventeen rarely appears in public it's unclear what kind of infection the prince house Charles Taylor this month London
CDC study: Teachers key to COVID-19 infections in 1 district
"Emphasizes the importance of vaccinating teachers against Cove. It It says teachers could play a central role in spreading the disease. It's schools where social distancing isn't followed, and masks aren't worn in the district that was studied. The infection was often pastoring in person meetings or lunches and then spread to the classroom. The findings come a week after the CDC unveiled new guidance on how schools can reopen safely. Metal fatigue may
More Than 2M Tested In Westchester County
"Is now tested more than two million people for covert 19 since the pandemic began a year ago. Westchester County Executive George Latimer says things are getting better. The county is heading in the right direction. You have a downward trend in active cases. Downward trend in the number of hospitalizations. You have a downward trend in the percentage of infections and you have a downward trend, the amount of fatalities over the week that is all a good sign, Vladimir says. They're now just over 6000 known active cases of covert in Westchester. That's down from more than 6600 on Friday and down for more than 11,000. At the end of January. Despite the
Andrew Cuomo says New York City movie theaters can open at 25% capacity next week
"Are about to have a little more of a social life around New York City during this pandemic. Starting next Friday, March 5th movie theaters can feel 25% of their capacity or Max of 50 people per screening room. Governor. Cuomo also announced Monday that covert numbers have improved to a point where pool halls can open around the state and feel 50% of their capacity. So long as folks coming in, of course, obey social distancing rules where Mass and If the billiards halls put up physical barriers to separate tables and parties, too, But also starting this Friday, folks who have been in nursing homes around New York missing their loved ones will again be allowed to have visitors. Only nursing homes in areas with covert infection rates above 10% would not be allowed to have visitors.
Pfizer COVID-19 vaccine greatly reduces virus transmission, Israeli studies show
"To Israeli studies have found that Fizer Cove in 19 vaccine greatly reduces virus transmission. Shedding light on one of the biggest questions of the global effort to quash the pandemic. Data analysis and a study by the Israeli Health Ministry and Visor found the Fizer vaccine developed with Germany's beyond Tech. Reduces infection, including an asymptomatic cases by 89% and in symptomatic cases by 94%. The findings air from a pre published study not yet peer reviewed but based on a national database that is one of the world's most advanced a separate study. By Israel's Sheba Medical Center, published Friday in The Lancet medical journal found that among 7200 hospital staff who received their first dose in January There was an 85% reduction in symptomatic covert 19 within 15 to 28 days with an overall reduction of infections, including asymptomatic cases detected by testing of 75%. More research is needed to draw a definitive conclusion. But the studies are among the first to suggest a vaccine may stop the spread of the novel coronavirus and not just prevent the people vaccinated from getting ill. Dr Jon Swartz and Burn cold clinical professor emeritus of infectious diseases at the UC Berkeley School of Public Health. The implications of this are enormous Republicans standpoints in vermin individual standpoint. If if the If these numbers are even numbers significantly less than this hold true, that is that once fully vaccinated. Well, first of all we know once fully vaccinated. It's Very, very, very, very unlikely. We're going to get seriously all and there's no evidence that you'll die after you being fully vaccinated. So we know that. But what if after you're fully vaccine, you get reinfected. We know you're not gonna get sick, but you could spread it. But what if you can't spread it? Or what? If it's very unlikely for you to spread it? It's gonna really mean that our masks they're going to come off sooner that we're gonna be hugging her loved ones a lot sooner right now. I'm fully vaccinated have been fully vaccinated now for this Just actually, three weeks today, um If I knew that I couldn't transmit this virus to my loved ones, I would My strategy would be very different. If I may ask you really come off. I could be hugging. Uh huh. But I don't know that yet, And so I have to still remain vigilant. And that is where a mask and social distance to be absolutely certain that I can't do that and think about all the health care workers. If the health care workers knew that they didn't it once they're fully vaccinated, they wouldn't transmit that would make an enormous difference in the hospitals. And think about just Transportation. It's just goes all the way down the line. So the implications are
COVID-19 Pfizer Vaccines in U.K. Show Positive Results After One Dose
"Data from the uk shows just a single dose of the pfizer. Biontech colbert nineteen vaccine can reduce infections. By more than half england's public health agency released the study which looked at infections in people eighty and older and showed a reduction of eighty eight percent after the second shot. According to the study the vaccine has also reduced hospitalizations and deaths. Today the uk outlined a plan to begin lifting lockdown restrictions. Next month schools will start reopening on march eighth and most other restrictions are expected to be lifted by the end of
"infection" Discussed on Start Here
"All makes you wonder exactly what was going on in the president what is going to happen now? So we're gonNA take a quick break. When we come back, we will talk about what's next for the president what's next for the country and why he was taking a right around the hospital last night we'll be right back. President had been up out of bed moving about the residents will only mild symptoms. Despite this. Everyone agreed the best course of action was to move to Walter Reed for more thorough evaluation monitoring I came here wasn't feeling so well I feel much better. Now, we're working hard to get me all the way back I have to be back right. So we're back with Martha Raddatz. Dr. Todd. Ellerman and John Chee who covers the White House and John that's kind of what been burning in my brain is is how scared was the president? How scared was the White House in order to welcome. Extra, intervention, my sources have been telling needs it's better now but heading into Friday night, the president was worried and so were his top aides. I mean what the two levels went down a there was a sense of panic among senior officials and the president's family to be quite honest I think it was very smart that the White House medical team did take president trump to Walter Reed as a precautionary measure Obviously, as we've seen from the reports that there are some concerns with how he was doing this is not a guy that likes to go to the doctor God knows doesn't like to hospital and we know so little about his medical history. To the president's supporters gathering at the gates of the Walter Reed Medical Center does right behind me you fights for us. We're GONNA fight for him Colbert's nothing nothing for him. So Martha the president didn't stay in the hospital though he left last night in a motorcade but just like what does take a spin around the block completely out of the Blue I also think we're going to pay a little surprise to some of the Great Patriots that we have out on. The president is seen in an SUV. With secret service agents we assume moments ago president trump surprising supporters gathered outside the hospital wearing a mask and flashing two thumbs up. For him so I guess in the end no matter how sick the president is, and we don't know exactly what is going down minute by minute he looked good in that suv he looked good in his tweet saying a surprise was coming and we have enthusiasm like probably nobody's ever had are people that love the job we're doing. We have more enthusiasm than maybe anybody but he did that energy of those supporters who've been standing outside Walter Reed. So no matter how sickie is he's never apparently sick enough to to want to market himself to want to get that energy from some of his supporters and yet you gotta think he put people at unnecessary risk to just away to those supporters. We still don't know how long the president has been contagious or when he contracted the virus health experts fear last week celebration of Supreme Court nominee judge amy conybeare may have been a super spreader event Dr Element safe to assume that that he is still contagious to people around him, Secret Service and whatnot. Oh, at this stage, we have to assume he absolutely is contagious and remember when you talk about the spread of this virus this is very different from influenza influenza. You can determine the number of average people who are infected with this virus is a recent study that came out from India, the largest contact tracing study in the world so far and basically. What it shows is that seventy percent of patients with covert nineteen don't spread the virus to anyone and at about eight percents of patients spread the virus to sixty percent of secondary context. So once again, we have to ask ourselves was this a super spreading event and when we talk about super spreading events, it's not just about the host. It's not just about a person having a high viral load in the back of their nose or mouth and coughing or sneezing on people. It's also about behaviors the president had to take it head on, but he didn't have to hold rallies where people did not social distance did not wear masks he didn't have to mock. Former Vice President Joe Biden for wearing a mask and reporters who wore masks. He didn't have to continue to go to event after event without wearing a mask, but I would get George. I'd push back on that because president trump is one of the most tested people in the entire country and there's a lot that we still don't know about this virus. Oh. Look how much contesting tell us and how much contesting protect us because basically the white. House's entire plan to keep themselves safe. WAS WE'RE GONNA test ourselves every day but we're not going to wear masks. We're not gonNA socially distance, but we're testing ourselves all of the time. So what are the are we learning what the limits of that strategy are now testing is very important, but he doesn't exonerate the wearing of masks, the physical distancing the handwashing. All of these basic infection prevention measures that we know reduce the transmission of covid nineteen so. It is of paramount importance that when you are in the White House that you are masked, that is critical. We know from other countries we know from multiple studies that this significantly reduces transmission, and as the weather gets colder, we know that more transmission is going to go from outdoors to indoors and let me tell you something Brad this virus loves the indoors studies have shown that there's nearly a twenty fold relative risk increase of transmission between being indoors compared with being outdoors. Every new poll out this morning it with us and says nearly three and four American seventy two percent say the president didn't take the risk of getting covert seriously enough for and didn't take appropriate precautions when it came to his personal learned a lot about covert I learned it really going to school. This is the real school. This isn't the let's read the book school and I get it and I understand you know you can't help being Glad for president trump that he's feeling well enough to do that but I couldn't help thinking so many emphasising thinking about those who lost loved ones who were not able to see them in the hospital who were not able to be near them or give them comfort. So many people have been canceling weddings, canceling events, canceling graduations, and yet there he was out and about even though he has covent. Martha Raddatz Johnson Tucci along with Dr Todd Ellen. Thank you guys for sticking with me. Really helpful in Tho-. Thank you Brad. Thank you, Brian. Voisin. Rumors over the weekend. This team was digging through all to get US straightforward facts more to come. Of course, as the President returns from Walter Reed will have more on ABC News, dot com or ABC News after the day they follow us it start here. ABC for the latest of all this. I Brian..
"infection" Discussed on The Bio Report
"Metaphor, we are developing the product, the broader range of indications, but we'll go from a community type of infection like Volvo vaginal candidiasis in the revision of both of our candidates bitcoin assist. Up to. deadly. High mortality. Hospital infections. Any Mona compromise subject like a mansion for Moanalua's spills or invasive ongoing factional refractory to other treatments. So the, it's a very broad range of indication that goes from the less severe infection like Volvo vaginal candidiasis where we are using a low those for one day or votto budget candidates, but treatment. One day treatment low does. A C A C semi-legal given for one day. When is a four ospital infection with infection deep seated inside the patients. We, we have to use a higher, those seven, hundred, fifty, million gum even sometimes for a few weeks or even for a couple of MOMS except diaper. All deep-seated. dipoto Fungal infections. How big a concern is. The potential development of resistance against the drug. Well let me say as an infectious disease specialist, I can tell you that sooner or later. Up, pathogens, they always find a way to become resistant. The. Pathogens microbes being around a billion years before asked and they will be around billions of year after is. The Important point is that so far? We've seen a ventilator risk for developmental resistance. So we expect like for other Antifungal to have probably a fifteen to twenty years before resistance really becomes a significant issue. For example, Makino Candians as a class, they would use. Gazan. And he has been only a few years ago. Two, thousand sixteen. We start to see INVA-. Kleenex. Some fungi becoming. Can't in? So it took a good fifteen, twenty years before i. became a problem. So we expect to our drag that would be very effective against pathogens that currently resistant of what is available today will one day developing probably. Yes. Let's. Destiny of all the antimicrobials and visit one thousand points, I want the May. Is Bet visas. Why is so important for the development of new UNTHANKED in general? Is because pathogen out of very smart? Very very smart. They find always a way to become an eastern NBC's twice showing them to support the anti-infective industry. Recently, we have seen some companies like. Bison mealy without realizing and me than a mouse in just a couple of weeks ago. But. They are going to support the anti-infective industry. It's important for our society that we continue to develop new products like eyebrows, jer to make sure that we have weapon. But confide the challenges of tomorrow. Margot Tagliavini President and CEO of Nexus Mark. Thanks so much for your time, today? Thank you very much. Danny equals my pleasure to talk with you today. Thanks for listening the buyer report is a production of the Levin Media Group, automatically downloaded this podcast each week subscribe to our. or through I, tunes or other podcast manager. Join our mailing list. Go to Levin Media, Group DOT, com. We'd love to hear from you. If you want to drop us a line or interested in sponsoring this podcast, send email to Danny at Levin Media Group dotcom. Special facts to jump Levin who post our? And John, ll bean collected, which performs..
"infection" Discussed on The Bio Report
"Marco, thanks for joining us. All my pleasure, then a four inviting me. We're GONNA talk about drug resistant Fungal Infections Sign Nexus and your efforts to develop Antifungal to treat these infections. Maybe, we can start with how big a problem resistant. Fungal. Infections. Today. It's a growing problem and simply because Antifungal. A unforgotten being to use many decades ago, and that are very few of them. Only free classes. One, the pollyannas introduce sixty years ago. That's all introduce four years ago, and Makino candidates introduced twenty if ago, and of course, we've all this time. Fungi had an opportunity to develop the fastest against these free classes. This is why we are developing a new class in order to overcome the growing problem of these. Phone. Calls. How threatening are these infections? Well the type section that we're treating. Difficult to treat an invasive fungal infections invasive from getting fashion. Infections meaning infection bloodstream of internal organs. Usually, they happen in patients water immortal compromised. So cancer patients with a undergoing chemotherapy or. Transplanted patients, solid organ transplant, bone marrow, transplant patients, and these patients. They don't have the emotional defense five vs infection. So using fictions. They are very aggressive. They can spread inside the body of the patients in mortality of visiting factions can be still. Now, we've a best treatment between twenty to fifty percent Wayne thirty to fifty percent, go extremely high mortality. You have, infections. Are Not internal like, for example, Mucosal infections of his office of the mouth of China. That, that can be very, very difficult to treat and these are we all the type of infection invasive and dilemma Khoza that we are trying to treat. Now we've our compound. We hear a lot about antibiotic resistance and the causes of that. Why are we having this problem with Resistant Fungal Infections? Very good, question Danny. Video. Not The resistance to antibacterial as being on the wrong line is because bacteria. Very. Quick in developing resistance and reason is because they are very promiscuous. Based chain the. Not Charlie between the same species, but also between different species of bacteria and very for development over resistant to antibacterial usually develops very quickly after a few years of being actual product on the market. I'm fungal. Infections and. July. Up the development is extensive slower. It may take ten fifteen years before the be significant amount of. Become, resistant, and these. These why? Now, we start to see the problem becoming bigger and bigger. When you start to see <unk> classes a been introduced point, you're forty years ago or even longer. And reason of the focus romantic materials is because They develop resistance. Very, quickly. And in very visas being before course over the last. Probably fifteen point years. But he's not <unk>. Antifungal. 's is becoming a major issue and you have new species amounting like a candidate horace of. Be Shown to be more drag resistance with high mortality, very difficult to control infections. Given the.
"infection" Discussed on The Doctor's Farmacy with Mark Hyman, M.D.
"Pharmacies mixed them and you can apply them vaginal to make it easier for the issues and help those good bacteria. Climb up your e thrown into the bladder and so but taking my mouth is also helpful to create that Nice microbiome help replete the Nice microbiome in the bladder area. We know that the cranberry we heard forever. That cranberry is really helpful. Because it has a substance that prevents the bacteria from sticking to the bladder lining so cranberry is really great. I you know I often don't want to get people to drink too much. Cranberry juice because it's high in sugar but you can get powders of cranberry and there's capsules of cranberry. That can that can be used. Md MANNO says another substance get unsweetened cranberry juice. Yes yes unsweetened concentrate that step. His sour money really works got Quarter Cup of that yet. He makes a little water and drink it. There's no sugar and really works and people can do it every half hour every hour two hours depending on you know and really helped break the cycle if they don't WanNa take antibiotics. I've had a lot of women who just trying to break the cycle and we give them things like cranberry concentrate or supplements. And there's another when you were just mentioning demand. Yeah always going to mention also that other place to put the the unsweetened cranberry concentrate is seltzer. Water it's Yummy that way but the demand is also another substance that prevents the binding of the bacteria to the bladder lining. So it's less likely to and they've done studies showing that two grams of demand can be as effective as antibiotics for prevention of a urinary tract infection. Yeah so so. Both cranberry demands can be used for prevention. And then if somebody starting to have symptoms they can really increase the amount that they're using to sort of stop that infection from coming on so I think those can be really helpful as can the probiotics we. We try to people getting any. Yeah Yeah I mean the couple things you want to watch for right if you get a fever if you see any blood in your urine If you get any back pain if it's not getting better or you really work with your doctor on this. Because they can't infections can become serious for some people in certain situations but those some of those things can be really helpful for breaking the cycle and and I think that's that's important. I worked with her with this one patient. You know we we. We added in some cranberry and D'Amato's she was taking it on a regular basis but then she also took it after intercourse. She took it frequently when she was starting to feel some sensation. Like an infection becoming on we work to make sure she was drinking lots and lots of water so her urine was more dilute diet head. Yeah we got rid of. I mean she was on a little too much sugar and sugar bed because it can it can feed the wrong bugs in the in the body right it can feed the yeast can feed bad bacteria. And that is you know also to absolutely right because we know that when blood sugar is too high that the immune system doesn't work as well right so for all those reasons. We cleaned up her diet. We we pulled in a lot. More of the good healthy have vegetables that are rich and fighter nutrients that are anti inflammatory and help can help support the immune system and and and we. We helped her get off of the chronic antibiotics. She was using because that is one of the best ways to help. Break the cycle of getting more and more infections so powerful so just to recap. We've had a couple of cases of recurrent ear infections and colds and sore throats and flus and bladder infections. But this really applies to anybody who's immune system is not working to get sick more often. Get sinus issues. The teamsters sometimes slightly different but we look differently at this lens of function at us when we look at Diet. We look at food sensitivities. We're look at the where sixty percent of your immune system as we nutritional levels vitamin D. I mean if your vitamin D levels low. You're you're much more likely to get the flu. And if your vitamin D levels are optimal your Reduc. Reduced flew by forty and seventy percent. Just that alone. Can we look at zinc levels and was of of your overall nutritional status right vitamin A? And so we're really take a deep comprehensive looking. Is there something else? That's stabilizing toxins like this. Little boy my tasty stabilizing the immune system so we really create a model of a real clear diagnosis sue history. Edyta analysis detailed testing if needed. It's a little bit different than what you get. A traditional doctor looks at these root causes. And then we kind of apply the method of restoring health. So we remove the bad stuff. Like you remove the Houston your move. The bad food and mation dietary factors. Maybe dairy whatever it is. And then you add in all the things that need to rejuvenate the immune system and we didn't talk about like sleep and moderate exercise and stress reduction and the whole foods diet and getting off processed foods in sugar. These are so simple. And they're so profoundly effective in terms of rejuvenating immune system and and that's what we all need to be thinking about right now in the era of cove nineteen because most of us don't think much about how to rejuvenate and enhance our immune function and. It's such a great time to really step back and say okay. What do I need what it? What are the areas I need to really focus on for self care? Where am I lacking? What am I not doing in terms of all those things? You've just mentioned right. How is my sleep? How is my stress? How is my house my Diet? How am I taking in too much sugar? Am I giving my body time to rest and and and really focus on that right now? It's a great time to do that. To help strengthen your immune system this important in this I mean we know that that gut health so important in resisting infection. Things like colds and Flus and getting your gut healthy and leaky gut sorted thinking a lot. Covert Nineteen. Why people are struggling. Asthma chronic illnesses people overweight. And I think I came up with this idea that they they're they're pre inflamed their pre inflamed so their body is already on fire. And you throw a virus on top of that like throwing gasoline on the fire and why people are getting really sick and dying from cove. Nineteen because of this thing called the cytokine storm cited kinds are the messenger molecules of your immune system. And when they're activated you get inflamed so these people coming pre inflamed and those are the ones who are really struggling with this right. So how do you get inflamed? That's what we're talking about. The high immune rejuvenation is to calm down the inflammation to remove the things that are driving inflammation to add things that help to reduce inflammation enhance immune function. I mean we know like we we talk about you know people sometimes think Oh. The are fat is just sort of sitting there. It's just you know we just have this extra fat hanging out but we know that that fat is is really an active endocrine organ it's producing and it's producing a lot of inflammatory. Immune orders. Hold your pants. Now's actually producing all these molecules and huge source of inflammation obesity and overweight and belly. Fat Is the number one cause inflammation our psyche to this and it is why we're seeing so much of these deaths from cove in nineteen because people are in for being overweight and chronic. Illness is also an inflammatory problem. And it's also caused by this metabolic dysfunction Tarzi diabetes. Even things like cancer are caused by being overweight or having in some distant so we it's all connected to the same underlying issue whether you're old and you have these diseases or whether young your weight it's the same problem so we're seeing so many people who are younger in the issues admitted but these aren't healthy and people. These are people who are overweight and they may have a chronic disease but obesity itself is not healthy. It's not it's not normal as being and you can and you can shift the level of inflammation in your body immediately by just changing. What you're eating quickly. I mean it's just amazing. How yeah I mean. I had a patient once who wanted to do. The ten Dave Reset Diet even go get pharmacy dot com. Learn how to get off sugar and starch and do the to reset. But she did it. She was sort of you know little. Ocd and she wanted to check her labs after ten days. I'm like no don't check your loved. After ten days dot going to change and she made me do it and I did it. And it was like holy cow like the inflammation levels has dropped dramatically in ten days. It doesn't take ten weeks. I mean people see it right. You can see the inflammation. Go Away because you're not as puffy. You know you look different when you look in the mirror. Your rings fit differently off. You know your weight drops very quickly. That's you know because the water weight goes away and inflammation. We also see it with the biomarkers in. Manama is pretty amazing. So yes so we. We have really in the midst of all this bad news about krona virus and Cova Nineteen. We have good news is that there is a path to a rejuvenation to actually resisting these infections to being Kovic resistant. Let's say And it's it's a PAP that everybody can follow some just basic stuff and there's going to be great articles that are posted along with us in the show notes so people can refer to those.
"infection" Discussed on The Doctor's Farmacy with Mark Hyman, M.D.
"Slash filter to access the. Thanks for tuning in so for this child you know we realized also because of all of this congestion and frequent infections and a lot of ear infections as a Kid. I said well you know what maybe we need to think about some food sensitivities that may be causing a lot of congestion for this kid and putting him at increased risk for these ear infections as a kid and infections now because we do know we do know that dairy and cow's milk is associated with increased risk of ear infections for some kids and also mucus production congestion. I know like Derek Mega Meal. Runny nose and congestion doesn't affect everybody. By by that way but it it does affect a lot of people that way YEP and and he was willing. He was willing to say okay. I'm GonNa the kid he was he was ready to say I want. I want to stop getting sick all the time. And so he was willing to go off of You know to do an elimination of dairy from his diet. And so that is one of the things we we really focused on and we worked on and and it really did help his congestion decreased. He wasn't getting sick much but but he but we did more than that because we also realize that he did some nutritional biomarkers. I realized he was a little low in zinc which is not uncommon to find. You know so I think is so important for your immune function fact in cove in nineteen. They're finding there actually treating patients with zinc because it helps to interrupt the viral replication and the viral binding to this sort of cells and insertion into the host DNA. So I I think it's really interesting to see that you know just even in this crazy horrible infection of cove nineteen. We're going back to basic principles of what's required to help the immune system zinc vitamin C. Which are being used intravenously studies. Yes and so for him. You know we added in like twenty milligrams of zinc and five hundred milligrams of vitamin C a day and and that was very helpful to to help him break this cycle. In addition we found out we found out that he had some elevated levels of heavy metals so his lead was was his lead was a little bit high. He was living in a home. He grown up in home. That was like It was built in the early nineteen twenties or so so it had more just lead in the water and in the in the walls of the house so it had been it had been refurbished. But it's still you know. His levels were higher than we'd like them to be and we know right what. We know about heavy metals. We know that high levels of lead are really a problem for both the neurological system in the immune system. But I think we also know that you know. Low levels can can result in people's immune system's not working optimally and also mercury lead also affect the gut interrupted gut function because leaky gut growth of bed. Bugs in there. So you got other reasons for this yes right. That's true that's very true. So so we also you know not only. Did we pull away dairy from his diet? We put him on a really good probiotic because he had been on. So many antibiotics saw past and probiotics. There's really really interesting studies on. How well they help the immune system. I mean we need to do a lot more research here and figure this out a lot more but but they can really help with breaking some of the cycles for people who are chronically. Getting sick I mean I remember this. Study of years ago was a pregnant woman who took antibiotics. I mean who took probiotics and compared to another group that didn't and the woman who took the probiotics during pregnancy their offspring had dramatically less eggs and asthma and allergy. Because the mothers took it so same thing when you give it to kids also helps dramatically with these problems absolutely and can help with with can help improve the functioning immune system for for some kids in certain situations and then of course we gave him that zinc and vitamin C. But then I gave him. I put him on a detoxification protocol. I really helped with getting these heavy metal levels down we. We did a a protocol that had a multiple different components in it but that was because we tested and we found that his heavy metals were a little bit high so we worked really bring them down with Glutathione Vitamin C. Some binding agents. Things that helps supported the detoxification system in his body and comprehensive approach really helped his immune system improve and it helped him get out of that cycle of getting sick. You know two to three times every winter and I think that's it's it's really. It's really fun to watch and see because we don't get sick anymore my sinuses. I this is the first year having antibiotics for my sinuses. It's just so it's so simple. I mean I I remember this kid. Remind me of the store and I was in the emergence from years ago and I was working mercy hospital in Springfield. Mass and the woman came in with her toddler. Who was probably like? Maybe about two years old and had just so many ear infections one after the after the other and I and I. When did this all star? She's like well. It was about a year old. I said what happened is my switched him from breast milk to regular milk. And and that was like this is before I knew about functional medicine or anything I was like. Oh well that's interesting. Why don't you take them off dairy and see what happens in the kid was fine so I I think we. Sometimes it's sort of that simple. I think often is more comprehensive. Because you won you change his diet you optimize his nutrient levels and you also in a deeper look at. His detoxification is mental burden. Which also factor so. You did diagnostic tests. That can help pinpoint these issues and you can really create a precision approach to each individual. So this problem but maybe somebody else who might have a different reason for their immune system networking. I think it's really important. Understand that we ultra wellness center and in functional medicine. Take a very different. Lens at looking at these chronic problems and say what is the cause how to get rid of the cause. And why isn't the body working properly you know? And when I learned functional medicine one of my mentors was guy named Sydney Baker. Who Sort of Yale Pediatricians? Brilliant Guy and he he was incredibly good at taking incredibly complex ideas and simplifying them into a few principles and one of the most important principles that gives me every day. Still today is very simple. Question is what do you need to get rid of in your body? That's making it unhappy. And what is your body need to get in order to get healthy. So what are the things that are the problems that causes easy? What are the missing factors that you need to have a resilient system? And so for the amuses saying so this kid who was he had too much dairy. It was bugging him to many metals or by rid of those things. And then you add in the things he body to function union out in the probiotics zinc vitamin C in. The body does what to do. It's like when you take out the bad stuff you put in the good stuff. It's just that simple and sometimes it's a tough job to figure out. What the bad stuff is that you need to get rid of. And what the good stuff is Anita. Get and that's the that's where the real no meet. A functional medicine is being investigate. Those things properly right and we don't. We don't learn that in medical school function as we learn how to dive deep into an expert. In what are the things that caused disease? And how do you create a healthy human? And I think that's the I think that's really the power of supplements. Sometimes people are like. Oh you know would have supplements matter of multi. Is this helpful as of urine. Yeah but but when when you when you can identify what deficiencies people have or what because of their genetics of right when you can really specialize and and give a personalized program for somebody. It makes a world of difference. You know I remember. I remember in my undergraduate degree in nutrition. And they were like. Oh you know. Don't bother with supplements really food. I kind of a program so I never took supplements I remember the first time. I took a Multivitamin I was like. This is amazing and it was a good quality one with good meth late of vitamins. I had so much more energy because I needed that extra menthylatim because in my genetics right but like so when you specialize and give a personalized approach. It really makes a huge difference for people. Okay so key. So we see recurrent ear infections. Recurrent sore throats recurrent colds and flu. We also recurrent sinus issues which are very similar. Case woman with chronic bladder infections is so common. I mean this is. This is something we see all the time we know that at least fifty percent of women get a at one urinary tract infection in their lifetime but lots and lots of women get many many more right and an percentage of women have recurrent bladder infections to the point where they're put on antibiotics for prevention right. They might be taking an antibiotic every time they have intercourse. Or was it about idea because because let's go back to the microbiome right we've got we've got we've got microbiome we've got all that good bacteria that lines are your e and our bladder and so that when we take antibiotics all the time that is killing off some of those good bacteria just allowing that bad bacteria to get back in there again right so so it's really we've got work to break the cycle with women all the all the time with the chronic urinary tract infections. It's something I see. I see so often. In my practice of women reason women get mad. They have very short distance between their outlet of their bladder in the vagina and then their bladder. It's very short whereas men as long as the Beker to migrate up there and then it gets affected by hygiene and sex and Yeah Shit. Most common cause of a urinary tract infection is the E. coli bacteria which you know comes from our gut and so there's like you said there's not a lot of distance between where the where the stools coming out and the you re threat and the and the bladder so it's it's not an unfair you know it's a common thing that we see but there's a lot we can do to prevent that bacteria from from taking hold so this woman she's a forty year old woman. Who had had bladder infections? You know her her whole adult life and was on at the point where she was needing to take an antibiotic every time she had intercourse and And really that was impacting so many other things now. She was getting Yeast Infections and she was and you know her digestion was getting off and so she we were like okay. We've got to get to this underlying work to break this cycle of chronic infections. And there's a lot of cool things that really help with with stopping that cycle of recurrent. Bladder infections I mean you talked about some of the basics right making sure. You're drinking a lot of water. Urinating frequently being after Sir keying after before and after sex right yeah wiping from front to back wearing cotton. I mean all the basics but then there's some stuff that really is helpful. You know to help break the cycle and one of those things are the probiotics. There's been a lot of really interesting research. Showing that there's certain forms of probiotics lactobacillus Ram noces and the lactobacillus which are good bacteria for the urinary tract system. Right those bacteria. Are you want to have a lot of in the urinary tract system that when there's good levels of those bacteria you know your things are GonNa work better? There might not be as high risk of getting some of those recurrent infections. Your all your practice Mistero. But you're saying there is a microbiome. Yeah absolutely absolutely and so So you can take these probiotics. You can take them by mouth We often will have compounding pharmacies mixed them and you can apply them vaginal to make it easier for the issues and help those good bacteria. Climb up your e thrown into the bladder and.
"infection" Discussed on The Doctor's Farmacy with Mark Hyman, M.D.
"Coming up on this episode of the Doctors Pharmacy. We'll see that. Somebody gets an infection right for this kid. Who was his ear infection or somebody else. It might be a urinary tract infection. Sinus infection that you're giving antibiotics but those antibiotics get rid of the infection but they also they also can get rid of all that good. Bacteria welcome to the Doctors Pharmacy. I'm Dr Mark Hyman. And this is a special episode called housecall with my colleague and friend and partner at the center of the medical director. Dr Elizabeth Boheme and this is a conversation. They should pay attention to because it's about how to prevent infections and given our current situation with Kovic Nineteen. We should all be paying acute attention on how to boost immune systems how to make ourselves more immune resilient and how to as my friend. Dr. Jeffrey Bland says how to create a process of Immuno rejuvenation. Like that Great Word. Which is how do we make ourselves? Immune warriors so our immune system is functioning on all cylinders. So one we may be able to resist getting infections. We'll talk about some cases on how we do that not with Kobe. But in general and to how if we get something we might not get that sick and I think that yesterday I was talking to Physicians Assistant. Who worked in the emergency room in a hospital in Massachusetts and she was saying how they saw probably thirty to forty patients. A day Most of them came in for testing with mild symptoms. I and then there was a few that were very sick who came in really shorter breath really struggling and unable to manage who had to be admitted to the hospital or intimated and I said how many of the patients that end up getting admitted to the hospital or in the ICU or on ventilators. How many of those were healthy in other words? How many of those who came in were overweight or had some chronic illness and said there wasn't one this is her right sample right but it's you know literally hundreds of patients over weeks. She's not a single one who came in healthy needed to be admitted to the hospital. They all had more mild symptoms. So that's a really important clue of how we can become cove resistant right. How do how become immune resilient and copen resistance? So we're going to talk about how to break the cycle of recurrent factions. Whether it's colds or Flus or bladder infections ear infections. How do we make ourselves more? Immune resilient so welcome to the podcast. Dr Bom you've probably the most regular guest I've had and we're going have lots more of you because we get into such great conversations about common problems with uncommon solutions based on functional medicine that really work and is what we do here tells you WanNa Center Lenox Massachusetts and it's so exciting now we can treat so many more patients because we're doing virtual visits were doing virtual consultations so even new patients. We can do virtually now because of the expanded telemedicine roles and it's really great because we can take care people all over the world virtually and it's Super Fun and easy and people get help especially now people have time to take care of themselves. They're at home. They can cook. They can practice more rhythmic lifestyle. They can exercise more and they can get into a actually better pattern important to now right. I mean I had a patient the other day he was like I am motivated to really make this stick now I am. I mean. She was working hard before. But she's like I have more motivation to really take your advice because I know that when I'm eating that refined process sugary food. It's not good for my immune system. I know that when I'm not doing exercise that's not good for my immune system right I. I know that if I'm really stressed and not giving my body time to rest and do my my breath work and relaxed my body. We know that's not good for my immune system right. So she's like I'm really motivated now to take this advice and to really focus on self care because like you say we can't always control the virus but we can control the host somewhat right. There's a lot that we can all do to really strengthen our immune system and you know I've been interested in this topic for so long because because I see a lot both with myself but with a lot of my patients of these chronic cyclical infections. Right people get know. Everybody's kind of got their Achilles heel right. Is that one person it might be. They get these sinus infections every winter or a couple every winter or somebody else it might be. They get urinary tract infections. All the time or or that that that kid who's always getting every colder flu. That's floating around strep throat. Right and it's uncertain. People are so much more susceptible. So it's been I've been working with patients on this for a long time and now that we've got cove in one thousand nine. It's it's so important that we really take these principles and and say okay. What can we do to break the cycle of always picking up everything that's floating around? Why what can I do to really improve the functioning of my immune systems if you go to the and you say Hey doc. I don't WanNa get these infections anymore. What do I do well next time you get sick. I mean I'll give you an antibiotic right. It's it's it's nothing we were trained to do. It's not their fault now. They just don't have the knowledge of the tools or even the insight that wait a minute. There's two things when it comes to an infection there's the bug and there's the host right it was. It was a very famous debate between Louis. Pester who discovered the bug? The pathogen and this guy named Claude Bernard who was a scientist at the same time another French scientists who said no no no it's the biological terrain it's the host that matters the most right. So is this host pathogen debate. But it's kind of a silly debate and at the end of pastors life. He says it's not the pathogen is the host And I think that's what we're finding with cove. Nineteen is that people who are not healthy are the ones who are getting really sick. And dying eighty percent are mildly affected or have no symptoms which is part of the scary part because people walking around shedding virus. And maybe all great and so. That's why the governor of New York said put a mask on right. Everyone's gotTa wear masks. It's law now but I think we have to think differently about this and say wait a minute. What do we know about how to create immune resilience how to create immuno rejuvenation how to make ourselves an unfriendly host To the microbes that were exposed to. Because we're all exposed to them right. I mean people with AIDS don't die from the HIV virus. The HIV virus cripples their immune system. Which means that they are going to die from things that we all live with in our bodies whether it's new assistance pneumonia or whether it's cytomegalovirus or whether it's a different bacteria like mycobacterium avium curricula. We we actually are living in a soup of bugs that live in us all the time. Yes and it's not a bad thing imbalance with them and so when we get out of balance there's a virus like HIV hijacking mean system. Or whether it's the fact that we have a crappy diet or stress don't sleep and have nutrient deficiencies and know. Don't take care of ourselves. Well there's a lot we can do about it. And that's what's so great about functional. Medicine is gives us some method of evaluating people and where they break down and where they're struggling and we're where they're MU system might not be working optimally and there's so many different reasons for him. We're going to get into that in today's podcast. So tell us about some of your patients that you've discovered how to actually work with something I also have seen in my practice. People get sick over and again and you're gonNA see these people like why are you always getting sick and then you start digging. And what are the kinds of things out of balance? What what's out of balance so so for the first I wanted to talk about. He was a ten year old boy and he was coming in because he was getting every cold and flu That was going around. His mom was getting frustrated because he was out of school almost a couple of weeks a year if not more because he kept getting sick and she she of course had to take off work and it was causing some disruption in their house but she was also really just worried about him. Why was he picking up every cold and flu? Going around We you know I got a good detailed history from him and he had multiple ear infections as a younger child so when he was you know his first few years of life even up to five he was getting lots of ear infections and and often treated with antibiotics right so he would get an ear infection and he would take antibiotics and they get another infection and it would take more antibiotics. He had a lot of congestion in his in his nose. And she's got even when he wasn't sick he was dealing with. And that's an issue. We know because when there's a lot of congestion floating around sometimes it gets stuck right so kids that have a lot of congestion in their nasal passageways. There you station tubes more likely to they've more inflammation and it's more likely to get stuck and then another infection grows and you get an ear infection for example. So he had these he had these recurrent chronic anyways. So this is just break it down a little bit. So what you're saying. Essentially is that if you're living a lifestyle or you have food sensitivities or something is causing congestion and inflammation in your sinuses and your nose in your throat. That sets the stage for recurrent infections. Yeah right so maybe. The treatment is into fixed the infection to figure out why there's this problem right. Because the the the congestion gets stuck and then gives as a breeding ground for a virus or bacteria overgrown infection to take hold and for it not to be able to get out of the system you know and for him you know for him he. He had these chronic ear infections but now is getting everything but so when he had the chronic ear infections. It's important to note that he he was given lots of antibiotics so I first. Five years of life was on multiple rounds of antibiotics to three times a year. Getting antibiotics for these ear infections and And and that is something we often see right. We'll see that somebody gets an infection right for this kid. Who was his ear infection or for somebody else. It might be a urinary tract infection or sinus infection. They are giving antibiotics but those antibiotics get rid of the infection but they also they also can get rid of all that good bacteria. That's lining the sinus passageways the digestive system the bladder area..
"infection" Discussed on Precisione: The Healthcast
"Regarding precision healthcare from the brightest people people in the world. Today we have a very special guest tonight. I'm so excited to speak with her. Today we have Dr Crystal Eisenhower Doctrine. Crystal Eisenhower's one of the rising stars of American biotechnology after more than twenty five years in medical research in biotech she was is named founding. CEO of a perio mix. This is a company that harnesses the power of next generation. DNA sequencing to who identify any known pathogen. Whether it's bacteria viruses fungi or parasite perio mix is the only company Anthony of its kind and scope in the world throughout Dr Eisenhower's career. She has demonstrated strong leadership in business and science and has dedicated herself to abridging the translational gap between these two worlds crystal. Welcome to the show. Good morning thanks for having me no problem. We're excited to talk to you. One of the first things we might WanNa do is kind of define some of the term so everybody knows who we're talking about so and you tell us a little bit about what next-generation DNA sequencing is and and how your work is bridging. This translational gap that we were talking about a minute ago. Sure so traditionally when we have wanted to identify an infection we look for one thing at a time and we've done that through a microscope microscope lens. We've done that by looking at the proteins that that coat the surface of the microbe. We've done that by looking at the person's thousands immune response against the micro-organism were we've we've had some newer technologies that can look at small snippets of DNA in that microorganism organism sequencing is is a completely new way to be able to look for these microorganisms. And what this is is a technology where we can pull all of the DNA out of the sample and re can I use this process called halt sequencing we can create a genetic blueprint or DNA blueprint of everything. That's in the sample. So we're looking at thousands thousands of fragments of DNA instead of just one fragment of DNA and this gives us the ability to see far more than we ever could see before awesome so somebody goes to the hospital and they're sick and the fever. The hospital does blood cultures urine cultures all kinds of cultures cultures. How is that different than this kind of test? What what kind of different information might we get through? Culturing is great great assuming that whatever is causing the infection can actually grow in culture. Ninety percent of all microorganisms are incapable of growing and standard entered laboratory cultures. So what has happened is we've completely missed so many things that are really there and that's resulted. Sit in people being told they have no infection when in fact they really do. One example is before with a large number of people who have chronic urinary tract issues and they've been told they have no infection because their urine culture is negative but when we run our testing we see that they're in culture is absolutely not negative. It's just that the micro organisms that we are able to identify through do the DNA are not able to grow in the urine culture. And so we just haven't had the right tools to be able to see the full picture Asked what's been going on in these particular cases while so I guess you know if if you do have a positive blood culture positive urine culture in like the acute houseful setting a probably means that you must be really sick if I guess. The organism is able to grow that much of if ninety percent doesn't usually grow grow that about right yes and now it just means that the the right kind of organism was there. There was an organism there that was able to grow in in. We've we've thought about infection in terms of just a few few hundred microbes so everybody knows about staph infection Mersa hello everybody knows about strep infection. Things like strep throat everybody knows about HIV. Everybody knows about Seedorf but the reality is there are tens tens of thousands of micro organisms. That can cause illness in a human body and the more we do our testing in the more the medical world looks at the complete microbiome of the human body the more we are able to connect these lesser known and previously not identified microbes with these chronic conditions or with these these overt infections. This is pretty cool. So do they have this kind of technology in the hospitals yet to do. You're Kinda testing. Are you working on trying to get these kinds of tests in the hospital setting zest for a lot of people present with in Illinois Trying to figure out what's going on right. So many hospitals have the ability to do. DNA sequencing day are using so using that technology to identify things like cancers or genetic issues with the person themselves so the technology is in the setting. But what's happened is they. They don't have the the software to be able to apply to infection. And that's really where technology from then the DNA sequencing part is high complexity. But something that you know. Hundreds of institutions have the capability of doing what they don't have the ability to do is take the the data from the DNA sequencer and make sense of it so for example when we not take a fecal sample from a patient and run our DNA sequencing that can generate up to a one terabyte the data file that is a very very large data file and its millions upon millions of bits of data. So how do you sort Through all of that information and where our technology comes in is we have developed the software to be able to sort through all of that that information and to be able to get a very sensitive and a very specific answer for all of the things that were in that sample so right right now we are offering a full service because most doctors don't have access to DNA sequencing technology but as as we mature and as the technology makes its way into a more traditional setting. Our software will be what they bring into the hospital settings so they've already got the equipment we will share with them the protocols to run for the specific infection testing and then they will use our software to be able to make these identification in using the equipment that they already have fascinating. So tell us a little bit more about your company in how you started the company. And why are you so passionate about this kind of stuff sore so I have five co-founders roofing two of them were out of the George Washington University one of them out of Boston University and they had come map with this initial software it was called pathos scope and they were getting some really amazing results from summit they went through a program called I corps which is the National Science Foundation Program that tries to help academic doc founders academic inventors take their technologies into the commercial market because the academic world is is a very different world bed clinical a clinical world or a commercial world so they went through this program and I think the the main thing that they realized that they really didn't have the bandwidth or the interest or the skill set to do all the things needed to take this idea into the marketplace and so fortunately I connected with them through Virginia Bio which is a biotechnology industry organization. Virginia and I had finished or I had just sold my first company and was looking for a new opportunity so the stars really aligned. Well I I brought in a lot of complementary expertise to what what my co founders had and so they brought me in the founding. CEO of the company and my job was to help them. Take this this really great idea and to get it into the hands of doctors and patients so that could have a true impact on the world and so that was five years ago and I've since built an amazing mazing team one of my other co founders Dr Chen. He's our chief technology officer he was one of the original recruits to on the business side of of the founders. We've spent the last five years working to refine and add additional capability to the software aware that our founders started and again building this really great team around us with sales people and software engineers. And you you know all the things that we need to to have a nice successful robust company and we've been one patient one doctor here at a time. Educating the world on what we're doing and why it's a value to the world Hudson so what brought brought your interest into this kind of field. What made you so passionate about what you're doing right now is? Is there a story to it or is there something thing that intrigued you throughout your career. That kind of led you to where you are today there is. I was always interested in medicine and and biology. From time. I was a little girl. My grandmother was very sick and she spent a lot of time in your doctor's offices assist hospitals and a lot of memories. Are there with her in these healthcare settings and I remember she would always towel all the doctors and nurses how. I was going to be a doctor when I grew up. And it was very very proud of me and very encouraging of me but what I what what I experienced with her was she suffered with. Chronic pain and the doctors didn't have the right tools to figure out what was driving the pain and so so the diagnosis was. She was a HYPOCHONDRIAC. And for some reason I don't I don't know exactly why I could could see that. She was genuinely pain. She wasn't making it up. She wasn't doing this for attention. She was genuinely in severe pain. They just didn't have the right tools and just watching this as I grew up watching the impact it had on her as a person but also watching the impact it had on her relationship with her family.
"infection" Discussed on Fresh Air
"<Music> They <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Advertisement> <Speech_Music_Male> <Advertisement> just look <Music> <Advertisement> at the world around. <Speech_Music_Male> <Advertisement> You actually know no. <Music> Don't look <Music> <Advertisement> but if you <Music> only knew how <Speech_Music_Male> <Advertisement> I drive foul <Speech_Music_Male> every hour <Speech_Music_Male> of every day <Speech_Music_Male> will I hope <Speech_Music_Male> you enjoy. Just <Speech_Music_Male> stay <Speech_Music_Male> here <Speech_Music_Male> in the city of <Speech_Music_Female> the dying <Music> <Speech_Music_Male> <Music> petite Ted <Speech_Music_Male> trained that salt <Speech_Music_Male> that it could <Speech_Music_Male> <Advertisement> <Speech_Music_Male> we saw the game <Speech_Music_Male> and oh how it feels so <Music> good <Music> be drunk <Music> on the field <Music> <Music> <Music> trump. <Music> <Music> <Music> By the way <Speech_Male> <Advertisement> if you're having trouble <Speech_Music_Male> <Advertisement> understanding what Dan <Speech_Music_Male> <Advertisement> Bihar is getting <Speech_Music_Male> <Advertisement> at in many of those <Speech_Music_Male> <Advertisement> lyrics. Join the <Speech_Music_Male> <Advertisement> club. <Speech_Music_Male> <Advertisement> I like what one of the heads <Speech_Music_Male> <Advertisement> of his record. Label <Speech_Music_Male> <Advertisement> recently said after after <Speech_Music_Male> <Advertisement> working with him for <Speech_Male> eighteen years <Speech_Male> quote. <Speech_Male> It's always clear <Speech_Male> to me that he uses <Speech_Male> a lot of words but <Speech_Male> it's difficult to figure <Speech_Male> out what he's talking <Speech_Male> about exactly <Speech_Male> <Speech_Male> just as Bihar <Speech_Male> isn't obsessed with <Speech_Male> technical perfection <Speech_Male> of his sound. <Speech_Male> Neither is especially <Speech_Male> interested in <Speech_Male> writing classic Pop <Speech_Male> Song Lyrics that <Speech_Male> track conventionally <Speech_Male> what what <Speech_Male> he's after <Speech_Male> and what he achieves <Speech_Male> is that feeling <Speech_Male> of being caught up <Speech_Male> in a mood of trying <Speech_Male> to rouse yourself <Speech_Male> before it swallows <Speech_Male> you whole. He <Speech_Male> <Advertisement> turns nightmares <Speech_Male> <Advertisement> <SpeakerChange> into dreams. James <Speech_Female> <Speech_Female> Kentucky <Speech_Female> reviewed the new <Speech_Female> album by destroyer <Speech_Female> called. Have <Speech_Female> we met <Speech_Female> tomorrow <Speech_Female> fresh air. My guest <Speech_Female> will be Adam. Entities <Speech_Female> who covers national <Speech_Female> security <Speech_Female> intelligence and foreign <Speech_Female> policy for the <Speech_Female> New Yorker <Speech_Female> in his latest article <Speech_Female> he writes about Iran's <Speech_Female> response to <Speech_Female> the killing of Qassem Suleimani <Speech_Female> and <Speech_Female> why the US is likely <Speech_Female> to face further <Speech_Female> retaliation <Speech_Female> and is <Speech_Female> also writes about <Speech_Female> what he calls the new frontier <Speech_Female> in assassination. <Speech_Female> <Speech_Female> Also talk with <Speech_Female> him about his profile <Speech_Female> of Hunter Biden in <Speech_Female> his articles about <Speech_Female> Ukraine <Speech_Female> and the false <Speech_Female> narratives spread by <Speech_Female> many Republicans <Speech_Female> during the Senate <Speech_Female> trial of Donald <Speech_Female> Trump. A hope <Speech_Female> you can join us. <Speech_Female> Fresh Air's the <Speech_Female> executive producer <Speech_Female> is Danny Miller. <Speech_Female> Our Technical Director <Speech_Female> and engineers <Speech_Female> do Bentham our <Speech_Female> associate producer <Speech_Female> for digital media. <Speech_Female> Is Molly Seavy Nesper. <Speech_Female> Roberta <Speech_Female> shorrock directs the <Speech_Female> show. <SpeakerChange> I'm <Music> Terry
"infection" Discussed on Fresh Air
"World Health Organization The equivalent organizations in The Great Britain France France China the China Centers for Disease Control and the other institutions countries around the world. Yes we need to be training. Scientists who will become virus hunters who will go into those caves in those forests Doing the hard dangerous work and will go into the laboratories doing being the molecular work to help us identify these viruses and we need to our public health officials to be ready with resources and information to To deal with these Outbreaks I containment contact tracing Corentin when it's necessary isolation We need need more resources and we need more skills in you know you began our conversation by saying this is a time for effort and focus but not panic. A lot. Yeah this is pretty alarming to hear Remind US why we shouldn't panic in part. It's just the fact. I think that a new thing something. It's called novel. Corona virus has a certain scare value to it And and being scared is useless being educated and and Understanding it and being ready to respond and support government response is very useful panicking and putting on your surgical mask every every time you go on the subway ride an airplane is not nearly as useful data Carmen. Thanks so much for speaking with us. David's pleasure to talk with you and and thanks for giving us the time science writer David spoke with fresh. Air's Dave Davies is the author of spillover animal infections and the next human human pandemic after we take a short break. Ken Tucker will review a new album from the Canadian. Rock band. Destroyer this is fresh air support for NPR from whyy presenting the pulse. PODCAST that takes you on adventures into unexpected corners of health and science plastic in the guts of deep sea creatures crying after anesthesia building. Your own Internet. Each episode is full of fascinating stories and big ideas. The pulse available available. Where you get your podcasts or at whyy dot org? Hi It's Terry Gross inviting you to check out our new online archive collecting forty forty years of fresh air interviews and reviews. You can hear my interviews with people like David Bowie aretha Franklin Johnny Cash. John Updike Tony Morrison searched for names. You're interested in make a playlist for yourself or friends at fresh air archive dot org. That's fresh air archive dot Org Canadian. Nettie and Dan Bay along admired figure on the indie rock scene. He's been a member of the clever pop band the new pornographers and is the central player in the much moodier band destroyer in recent interviews. Bay Hara said the new album have we met is influenced by sources as various as the twilight zone and Edgar Allan Poem Rock Critic. Ken Tucker has a review of have we met.
"infection" Discussed on Fresh Air
"Hear the experts saying that. Those are very helpful. In containing the spread of infected droplets from people who are infected containing coughs containing sneezes by a sick person but much much much less effective in protecting a well person from the sneezes coming out of another person so in other words where mask if you're sick if you're coughing as a courtesy to people around you don't be nearly early is concerned about wearing a mask just as preventive when you step on an airline or go to a big store right I think the CDC recommends that ordinary citizens citizens don't really need to worry about masks but health work at probably. I think the I think the CDC has also saying look ordinary people. We have shortage shortage of masks. Let those masks be used by healthcare workers who need them most rather than wearing a when you go to the hardware store. Well this outbreak you tell us is not exactly random. This is a pattern. That's emerging And you say that a lot of these viruses that we have seen presenting threats to public health or examples of something called Zoa notice. What is it right? tzoanos is an animal infection. That's transmissible to to humans The animal in which the the the bug virus or bacteria or whatever lives is called the reservoir host a virus can live in an animal discreetly unobtrusively and then occasionally spills over into a human victim. Which is why we're my book title comes from And those then our zone. Arctic infections in the human population not now the science. Here's interesting remind us what makes virus distinct distinct from other pathogens viruses not a cellular form of life of viruses A little package of Genetic material inside Sidik inside a protein capsule and that's all it can't replicate itself except in a living cell of some other kind of an organism an animal animal a plant a fungus of bacteria viruses have to have a host that helps them copy their DNA or there aren a their genetic material and and produce more copies of themselves So it's a it's a very very particular form of organism people even and Debate whether it's actually a living form or some sort of a devious mechanical phenomenon viruses but very different from bacteria and infectious fungi in the other kinds of pathogens that infect humans right it doesn't have a biological identity of its own it needs a host leads a host to replicate. That's is right right now. There are viruses like smallpox that do not come from animals and they're easier to eradicate right. That's right I say in in my book Everything comes from somewhere ultimately we're We're relatively young species. Someone's sapient so our our oldest infectious diseases uses a unique to us like smallpox have precursors. That were originally animal confections but smallpox is one that now. Well Oh now. It's a radical from the human population And one of the reasons it could be eradicated that we could stomp out smallpox. Human disease is because there is no other other animal host for smallpox. When there's an animal host then it becomes much much more difficult to eradicate or even control an infectious virus right? So if we find a virus that's troublesome and we managed to quarantine those who are infected. Stop it spread. Maybe even we develop a vaccine ax. Seen we think great were in the clear. We really aren't are. We know now and in fact one of the very first questions when a new virus appears a novel Vo Corona Virus or virus. That's new to humans of any sort One Group of scientists and public health people start talking about well. How can we treat this? How can we control it? How can we prevent it spreading through the population killing a lot of people and another group of scientists addressee? Question where did it come from. What is the animal animal host? It had to come from somewhere probably some sort of a wild animal. And how did it spill over into human so they they work on the the origins and the causal questions as opposed to the control and treatment questions and those are the questions that were most fascinating to me in that that I wrote about it in the book right so there are these animals that have this virus and it doesn't kill them. It doesn't make them sick. They just haven't they. That's perfectly happy. Lives you begin your book with the story of of virus that appeared in Australia which killed horses quickly and dramatically and painful info and a number of people who treated them and they had to do this detective work of finding what the reservoir host. What animal had this virus virus How you do that? How do they do that? Well in this case it was a it was a virus that was killing racehorses in a stable in A suburb of Brisbane Australia called Hendra and some disease ecologists went in and said well. We've got we've got to identify the the the reservoir host. Where did this virus come from and In particular and a man named Hume field was a veterinarian and he was working on a PhD in Ecology. He made this his dissertation project. So he trapped all kinds of animals in the area surrounding the stables in the meadows of Hendra and elsewhere He he trapped rats and insects and small mammals of various different sorts and also trapped. Some bats I thank you caught a bad and offense and tested. It tested all of them to see if he could find evidence of this virus and he found it in the bats. He founded in two who species of giant Fruit Bat. That were native to that part of Australia and then the question became. How did the virus get from these giant fruit bats into do these horses and one of the fellows who worked on the response to this Another vet a veterinarian took me out to a meadow outside side of this suburb of Hendra and it was a big hot grassy meadow where they pastured horses For instance one particular mayor when when she was pregnant Senate they pastured her there and there was just a single tree providing shade in the hot sub tropical Australian sun in this meadow and uh this Veterinarian pointed to it and said there it is. That's the bloody tree. meaning that's the tree that this horse took shelter under for shade. It was a fig tree and it attracted fruit bats. The the fruit bats came eight. The figs dropped fruit pulp dropped saliva dropped feces. ABC's onto the grass below the horse. Eight the grass picked up the virus than she was brought back to the stables and she infected the rest of the horses so it was hume fields detective work that identified with help from some other people that these two species of fruit bats the reservoir host of Hendra right so so the virus goes from the bats into the horses and the horses die. People get it from the Horse's and a critical question in these viruses is when they reach people they do. Do people only get sick if they come into contact with the animal or can they convey the virus to each other person to person right. That's right prisoner. Prisoner Person Transmission. That's a really really crucial question. In all of these ansars it was quickly discovered that there was a person to person transmission of the virus. Ars in the case of this Hendra virus and Australia. There was no evidence of person to person transmission. And that's one of the reasons why a Hendra virus has remained virtually richly unknown to the world and the people who got infected where the people Veterinarians and Horse Trainers and horse owners. who were trying to save? The lives of those horses So in in the case of the very first outbreak in at staples I mentioned There were three guys. Veterinarian the stables owner and trainer and in a stable worker And they were reaching down the throats of these horses as they they gagged on their own bloody froth and vomit reaching down the throats with their arms trying to clear the air passages and So that's close contact. They didn't know that there was a dangerous virus involved and Two of those the three got very sick and one of the three died so there are all these tens of millions of viruses out there why are we encountering them so much more these days as well the simple answer is that we humans are so abundant and so disruptive on this planet that we come in contact with these things. They're seven point seven in billion of us. We're we're cutting the tropical forests. Were building a work camps. In those forests and villages were eating the wildlife where transporting wildlife life round the world we're raising a lot of domestic livestock that become exposed to viruses through wildlife. We're doing all these forms of of disruption that I I say sometimes that you go.
"infection" Discussed on STEM-Talk
"All mammals are natural secondary hose for talks exa plasma gandhi and you had a twenty sixteen paper in the journal plus pathogens that described how toxic plasma infection leads to a disruption of neurotransmitters in the brain and dan you postulated that the infection triggers neurological disease and those who are already disposed to such disease so can you talk about these tests also the significance of your findings for this paper. Yes there have been a lot of carlotta studies suggesting that if you're infected with toxic plasma you are more susceptible acceptable to neurological disease and that might be including things like schizophrenia and so my question was will high with that happen and and we want it to look in conjunction with my neuroscience colleagues look at more of the changes in your chemistry that might be happening in that an infected brain rain not just the immune response colleague are taught fiasco here issue website and an expert astra sites and he looked at some of these movies type generated righted route to some of our e._m. At all these astronauts incredibly swollen very different morphology and he was kind of astounded that are mice were still alive and this astra site reactivation. This is a pathology one of the biggest roles that astra ostracised play as well as being able to do things but as minallah just think of like pretty sight kinds of chemo kind it can also control the piracy they a really really important in regulating extra cellular concentrations neurotransmitters as we measure particularly the neurotransmitter glutamate which is the primary exciting your transmitter brain and astra saints control right the sign up with glutamate transporter couch lt one and once a neuron fires its transmitter into the sign ups vin if that grooten it wasn't cleared up than would be no signal to noise ratio and the neuron would start to get it we get overexcited in and it would become a pathological process us so we looked at asha sites at the ready to do the strong <unk> expression of guilty one which is significantly down regulated following action x ray also measured using my dialysis extra cellular concentrations gruesome eight and a bunch of other amino acids and burned and and at chronic infection so after three weeks the concentrations uproot me go really significantly higher and as a result oh we think we have differences in the masala jackie and function of neurons so we lose dendritic spines and <hes> the way in europe essentially communicate with each other and we also measured are with my colleagues. Devon binder here in the websites go medicine. He focuses on epilepsy. Let's see actually he. He runs monday friday and take its brains from people with severe portsea tuesday wednesday thursday. He said an an amazing colleague to have and we did e._e._g. In mice infected and demonstrate that massive power loss in many of the circuits in infected grain. I think talks apart from infection can have the potential to have a very specific effect on mice behavior is it's designed. Almost it's too easy to manipulate mice behavior so that the very specific thing but changes in your transmitters in the brain in general could have a much broader effect effect on people that are susceptible to perhaps genetically susceptible to neurologic <unk> first place not my include schizophrenia other diseases like epilepsy sa- phantasm emma and your paper from plus pathogens in two thousand sixteen examining the the effects of toxic plasmas disinfection on the g._t._1. Glutamate transporter only included female mice so does the sex of the animals change the effect of the infection listen. We've done both male and female rice. I think that's really important and i just for one reason mandated it because so many any drugs are only tested in male mice because they're easier to use because they don't have these changes in hormones much more stable reportedly <hes> so we've done it in male and female mice and we have also done in conducted these studies in resistant assistant susceptible strains so we definitely see behavioral changes and now my says thinking about the work you've done in the lab with mice vice. Have you any thoughts on whether there might be differences. <hes> related to how toxic effects in animals in the wild or would you think could. It'd be a straight up model of how that would work yeah. I think it would be nice afraid to hiding. If you often see my second row perhaps that one's the talk talks positive one the brave one but it would be really good to have all these genetic variations in mice. Yes and no colleagues punk examples done at pass infections in lots of different wild mice and i think there's a lot to be learned from studies like us would think so in terms of neurological disease you previously mentioned tax plasmas strong correlation with schizophrenia and as i understand it's not the tax oh plasma is director only cause for schizophrenia but rather that you believe the parasite's presence appears to be one of perhaps several precipitating tainting factors. Could you talk just briefly about schizophrenia. In the context of gandhi yeah there has been strong correlation and it been in studies done by <unk> tori and rub your can the family foundation that have been instrumental in can of driving a lot of this research and and they have a lucht schizophrenics and there there's a strong correlation with tux plasma section a recent study out and this month i think cohort off twelve thousand individuals and denmark and overtime and a game that supported this correlation tux plasma in schizophrenia but some of these neurological diseases they can be a wide range of disease what we measuring. How do we know as more of a a spectrum but i think if the parasite is present in in the brainy could be a trigger for something underlying so some parasitology have said that tax applause mrs infections and asymmetric humans result in a silent partner that serves no role is this true first of all what are the arguments for and against a role of toxic plasma factions in the health of otherwise asymmetric humans and is it fair to say that the parasite is not as layton or even as dormant as researchers want stop yeah so the likelihood is that aren't many cysts in the brain of talks infected and do rituals highly-infected mars you might get three thousand cysts and as you think of the millions millions of neurons in the brain the number of cysts in the brain lightly to be pretty low a a human brain and most of the time i suspect that infection evasive dramatic and that's one of the really interesting things as well that despite despite having a power set in your vein despite having all these immune cells in your brain you are clinically quite unaware of it and so that route actually actually help us to understand what is a well-balanced immune response in the brain and if we can understand those processes are can we apply them when there is serious clinical pathology in the brain so i mean this eighty percent of people infected and fats in the know all crazy. Don't all have schizophrenia. It's got some the scots and the french have close relationships. I i hope i'm not insulting anyone by saying the <hes> the graduate student isn't that did the guilty one paper is actually french so i took advantage of that teaser as much as possible <hes> and then if you look it assist and safety lou kit pass hits the dividing though system not necessarily dormant related the parasites do still continue to divide sometimes you do see information around assist how often they are reactivating and when they are dormant perhaps is a lot more assist heterogeneity than we appreciate and whether in one host they have systems are more likely to react rather than the other. I think that is some of are future christians and on that note. Do you think we should be looking at the effects of radically talks a plasma innocent magic humans if so do you have any thoughts on how this might be accomplished. I think if you're a symptomatic you should love your parents and the drugs that we have to get rid of toxins are actually pretty limited. We have drugs that will control the fast replicating phase of the parasite but the pretty nasty theirself based and in their contra indicated during pregnancy and we have no drugs at this point that really remove the cyst from the brain. Which is you know a pretty the high bar you know their intracellular inside neurons and normally to we don't really want to go in kill too many of those infected cells so i'd be reluctant to talk about roger keating anything actually but i'm any organism but terada kate something in an e symptomatic individual pitcher end up doing more harm than good. There are some reports that humans that display risk taking behavior are more likely to be infected with t gandhi so this includes is a higher likelihood of infection and those that die motorbike accidents as well as increased entrepreneurial spirit and students that are infected so do you think there's enough evidence to suggest that t gandhi my alter risk taking in humans i think we need a little more evidence but anyone that does a bungee. Jumping must be taught punched him <music> but i i love the the entrepreneurial spirit and students. I think that is a really interesting angle that are consistent reports of this carnation relation with car accidents. I think there was another one with truck. Drivers is wow so. I i am going to fence list but to be honest. I don't think there's a huge which might have actual evidence but there's increasing carlos of studies. I'm sorry no. I think that followed on the line yeah. This has been with us a very long time and one wonders if it could have potentially no this is a reach but could potentially we encourage some populations to be more explorative and to yes and move up into europe or whatever the example is. They get on that canoe right. Who's going to be that person that got in the canoe and paddling wasn't going to be that person. I would check back to ghandi is the first person to eat in easter infected good. After the two thousand sixteen paper was published. You were quoted as saying that for the first time it has been shown that the direct destruction of a major neurotransmitter has matter in the brain resulted from infection as a result. You said more direct mechanistic research needs to be performed to understand the realities of this very common pathogen. Is that what you've been working on since two thousand sixteen yes. We've actually been investigating the mechanism of j._t. Run down regulation so we believe that direct infection by the parasite south communicate the jail to on pathway the guilty one has done regulated and many neurological disease is not just when you get infected with talks plasma. My gut instinct was that it was more information and it's still may contribute as well but we have lots of dayton habit demonstrates that took supplies invades and astro <unk> which is also not extremely common can lead to the dilation of this transporter wrecking on that. We're also looking at the bit. The parasite is in a niran at this time and in the brain that the the conversation between ascites neurons is absolutely fundamental to the regulation of neurotransmitters and tho- jail taiwan gets up regulated in astra sites when neurons fire unlocked because clearly this no more need for it and so neurons a regulating the expression of j._t. One on the astra site using xs uh-huh and we can see following infection of neurons and cyst formation neurons got the x. number and distribution changes or so. We're investigating that astra site near on contraception coming and other people also i must say that <hes> i replayed her shown on changes in gabon these changes in dopamine as well so this a definite consensus that near chemistry in general is markedly different hunt by so traumatic brain injury p._t._s._d. And sucide a recognized as being significantly interrelated in active duty and veteran populations and can you comment on the impact of gandhi infection altered response to physical and psychiatric exposures and military relevant neuropsychiatric illness right so that the parasite infection it south could have potentially a direct effect on how the brain responds inst- to trauma perhaps eight could have an effect on potentially the behavior of that individual to start with but also we can't forget that the are changes in the inflammatory response in the brain as well thanks to infection the whether that helps or hinders multiple insults to the brain. I think has to be worksites. Repeated hits to the brain in our is thought to lead to very different response than than just one example. I think it's the conjunction between the possibility of direct passe manipulation on neurons circuits circuits that could lead to.
"infection" Discussed on KQED Radio
"Reverse is also going to happen, which is that. If we use antibiotics appropriately, we don't actually have to make the investments in in in your drug development. The amazing thing about all. This is that there are no alternatives to antibiotics right like in terms of effectiveness. We have to solve this problem or we're in big trouble. You're absolutely right. And this is what's really worries me about this problem? The only alternatives we have ought to prevent the infection with vaccines, infection control. What have you? But honestly, we really don't have a substitute for antibiotics, and no one has figured out that say in fifty years from now we won't need antibiotics because we have ex- maybe will appear. But right now, no one is able to see through to see what does x really will be. We really don't have a substitute for antibiotics. Now, this is clearly not a game that can be sustained or one that can win by simply innovating to stay ahead, and their ideas, African borough from energy that are helpful in thinking about how we might want to do this in the case of antibiotics as well. Now, if you think about how we deal with energy pricing, for instance, with consider emission stacks is which means we're enforcing the cost of pollution on people who actually use that energy. We might consider doing that for antibiotics as well. And perhaps that would make sure that antibiotics actually get used appropriately. And certainly consumer education works very often people overuse antibiotics without necessarily oh prescribed too much without necessarily knowing that they do so and feedback mechanisms have been found to be useful both on energy when you tell someone that using a lot of energy during peak hour,.
"infection" Discussed on KMOX News Radio 1120
"Now exposed to your antibiotics kills off all the easy to kill bugs. And then all that's left behind are the harder to kill bugs, which then can if they caused you infection again become harder to kill by antibiotics, so antibiotics don't work on colds don't work on sore throats, don't work on the flu. Absolutely. Yes. We there are some antiviral drugs that work against influenza the flu virus, but for the most part, the common cold, and you know, some of these respiratory ailments that we get in the wintertime antibiotics just don't help and taking them is not gonna make make anything better for you. And they do work on bacterial infections like strep or hoping cough that sort of thing. Absolutely. Yeah. There then we need to be using them for those things. And so when you have a real diagnose bacterial infection. Somebody takes a culture somebody kicks a test. And then they say, okay, you have this bacteria. That's a very different story. But for the most part, viruses are more likely to cause a whole syndrome of systemic symptoms. So when you get an upper respiratory infection. You know, you have muscle aches pains, sometimes abdominal stuff nausea vomiting diarrhea bacteria. Don't usually do that if they're if you're down with a bacterial infection. It's just going to be us like the strap strep throat, you just have throat inflammation, you might have fevers. But besides that, you're not gonna have symptoms throughout your body. Whereas viruses are more likely to cause other SIMS symptoms everywhere else about ear infections and sinus infections, well, ear infections, especially in kids are a different story again kids, they can get ear infections very easily very quickly because of their size and essentially the year. Tubes you canals get clogged up very quickly leading to infection. So getting a kid checked up by healthcare specialist pediatrician very important to make sure they don't have an ear infection. That's bacterial that would need antibiotics, but for most adults most adults don't. Get your infections, and and even sinus infection, sinus infections, really don't need antibiotics unless they've been persistent for long period of time, the key for sinus infections, is drainage. She's keep keep the sinuses drained using nasal sprays. I just use nasal sailing and steam inhalation, and that can help a lot just to keep things moving. Let's stay with prescription drugs. A new study this past week takes a look at how often we get our prescription drugs renewed its Canadian research, but it's got American experts concerned to the study found nearly half of people who take certain prescription drugs continue on the far longer than is recommended or safe. Antidepressants proton pump inhibitors to treat heartburn and stomach acid issues, and this phosphates used to treat osteoporosis and prevent bone loss. The problem too, many doctors are automatically.
"infection" Discussed on The Healthy Moms Podcast
"For them as well and helps. I sleep which I know a lot of parents really grateful for their kids to sleep a little better. So two reasons to try that one. What about from the mom side? Because it seems like these things don't necessarily happen in isolation and like can infections be passed from other child or can these things be transmitted through families? Absolute actually never. Myself, having practice like heads, I'm just wasn't the direction that our practice started. And then I started getting moms and I was helping work with them their lime. And then once they started feeling better there, bring kids in. So as are seeing this pattern of, okay, mom has line now, Darras lamb. Mall has live, well, son has line, and I've had so many patients go through that that I started getting into the research of as as possible. And it has been found haiku relation that if mama's infection is possible for the children. Now actions not to mention some of the places be big up. Parasites are outdoors, so the lakes walk around barefoot playing in the dirt. So if the mom is out there and doing those things, time to kids are too, so could be environmental awfully, could it be transferred even euro very possible? Fascinating. I've even seen. Information about the potential that lime for instance, can even be sexually transmitted between husband and wife. I don't know if that's true cross the board, but there seems to be maybe some initial research there because it is an infection, but definitely makes sense as far as mom to child and that it could be like at least exposure could be there for all members of the family. So when someone comes into you and they have one of these potential problems, like you said, it's very rarely like a single thing. So where do you start? Is there kind of the process you normally go through with people to to start figuring out what those causes our soul. When you walk into my office, go through several different times testing. I gotta have you love like whole metabolic assessment. Pairs of Osprey there. So if you hundred questions and ask you anything from how you deal with eating food as far as blood sugar and energy too high, you slave and sweat and your cravings so that I can get a really good idea of hell systems in your body were based on your opinion because bloodwork isn't always accurate. Blubber link tells us when you are about seventy five eighty percents sick. That's what your tests go outside those medical ranges. And a lot of times kids especially don't fall those medical rate. So those assessments very healthy and alive earns the difficult Seinfeld about flirt. Kids said you the best you can and I'm gonna ask you a lot of questions and we're just gonna move might patients that are non verbal cystic, and we are able to get enough information for on that. Another thing I do is do life Selma Crosby so I will. Look at a drop of blood on TV screen in front of the parent right miles, and we'll kind of look through there and see everything will rider sometimes things. Great. I just had a kid come in the other day after I had seen his mom as patient and his blood was all stuck together could move it all at a couple of different samples because I thought, no way this gets too young for the blood little quick that that's typically a very, very sick patient. But once I was able to really question the moment and song the summer twelve, so he could answer questions, just fine. I was able to find out hit the just Trump does work. He's been high both IRA before hyper thyroid before he's had high cholesterol, low cholesterol. He has all kinds of just of the sheet, make more sense to me, and then we Ron actual outward. So I can get some medical standards on things so that we can track it to the lab. And then from there do some different. Eastern medicine testing, checking through different acupuncture types ests, whether it's pulse, Tong, Ori, muscles, testing, to figure out all the different information I could get is so many parents been through it was for medicine. You know tests, so they're coming to be looking for. Is there something else I can help my child?.
"infection" Discussed on We're No Doctors
"What's happening here the cat scan to yeah yeah yeah so basically like you should have it should be like a lot of empty space that should be a lot of black holes are giant caves and then if you have an infection you'd see like a little tiny bit of grey at the bottom of the sinus but you know like whatever mine are were completely gray there's no there was no room for the relate just tiny little specks of black and and that was like when i was essentially not sick so it was like what i was sick it was even worse so just sort of like living with this blocked these blocked sinus passages forever and then i think it's it has just been getting progressively sort of worse over the years that inflammation and stuff because just tissue it's just inflamed tissue or maybe some like polyps in their whatever that they go into in little he said micro bone fragments sounds cool so what was it policy it's just swollen shut yeah and and i didn't just because a lot of people have had similar surgeries or different kinds of surgery i had no turban oi problems and i had no deviated septum problem which turban on a lower sinus issues and that prevents people from breathing at night or they have get sleep apnea and stuff like that yeah so i didn't have those issues so like sometimes i think when people have i think deviated septum is real can be very painful because they have to go in i think they stitch it i don't know if you break your.
"infection" Discussed on UFC Unfiltered with Jim Norton and Matt Serra
"'cause like no antibody and it and i was like okay i feel better but then as soon as you start what'd you do that hippie shit close takes thing they said because like the way my weight cut was going go if you take time onto antibiotics it's good that you're gonna blow up it's going to be hard for you to cut way shows practical and this was when you could still take vis so i did like one of those vitamin i and i did feel better but also not pushing myself as hard but then when you put your heart self hard to cut weight when you're lacking nutrition they normally are in your my body literally like went to shit and then he's going to die you realize medicine works like holistic stuff is great but like a lotta time night you just take some antibiotics spittle i went to the hospital right after a head like a liver infection kidney infection stomach flu bronchitis like i had your mess everything and like i try to keep cutting way because it was a huge fight i just coming off of a loss and unlike share it you know i have to do well and then it like literally just wasted a great thing to stop as well when somebody wanna fight so bed and then to chew stopping always hard for me i have to yellow her in the front everybody like stop you're going to die you wanna die you never gonna fight anymore will you have to pull out too sometimes happened amanda i'm always could my sinuses are awful so i love talking about noses with how is your breathing also having other things you tell you i find these sort treatments solo therapy all sweet sought sweep tear up you'll go in the room the room have like salt all over you breathe also see yeah yeah sky avoid salty always as unsalted nuts don't be afraid of some soda in.
"infection" Discussed on WDRC
"A call from a natty plo lane view uh that seen uh new jersey long island oh please if you wanna look you're out there in the nestle county cut late mmhmm the last town before suffolk county okay so what's going on anyway i thought i had a uti a urinary tract infection and uh right around bright before christmas and i went to one of these uh i had like a lot of urgency going to the bathroom every halfhour so i went panic they went to one of these um walk clinics dr the box and he'll right and she said i did a urine sample and she said he came in she said my you have uti uh and i'll send this out to lab okay you know to be cultured yet though i am not as reasons at least ling was a little is there's a couple of ways to determine if you ever your truck virtual first of all you have you urgency but that doesn't necessarily mean that you have a urinary tract infection of him many women are attuned to the signs of an impending urinary tract infection uh you can do of what's called us a your analysis which is a spot test he quickly reveals whether there's blood or white blood cells or is something called leucocyte as to race which is a sign of infection basically it the indicates the presence of plus in the urine and then a decision is made okay heavier near attract infection then they send another part of the sample was called the culture and sensitivity to lavn i may take a few days to come back and that will tell you a a uh how many bacteria have what type you have and most importantly to which bacteria you are most like our to which antibiotics you most likely to respond because of the sensitivity means is the back syria and your urine sensitive to many of us so much antibiotic resistance that sometimes the first choice by the doctor in the uh in the.