35 Burst results for "Gilead"

Saul's Unlawful Sacrifice (1 Samuel 13: 1-14)

The Bible in a Year

02:22 min | Last month

Saul's Unlawful Sacrifice (1 Samuel 13: 1-14)

"We're reading first Samuel, chapter 13 of 14, and praying psalm 58. First Samuel chapter 13. Saul's unlawful sacrifice. Saul was years old when he began to reign. And he reigned, and two years over Israel. Saul chose 3000 men of Israel 2000 were with Saul in mik mash in the hill country of bethel. And a thousand were with Jonathan in gibi of Benjamin. The rest of the people he sent home every man to his tent. Jonathan defeated the garrison of the Philistines, which was at giba, and the Philistines heard of it. And saw blew the trumpet throughout all the land, saying, let the hebrews hear. And all Israel heard it and said that Saul had defeated the garrison of the Philippines, and also that Israel had become odious to the Philistines. And the people were called out to join Saul at gilgal, and the Philistines mustered to fight with Israel 30,000 chariots and 6000 horsemen and troops like the sand on the seashore in multitude. They came up and encamped at mik mash. To the east of Beth aven. When the men of Israel saw that they were in straits for the people were hard pressed, the people hid themselves in caves and in holes and in rocks and entombs and in cisterns or crossed the forge of the Jordan to the land of gad in Gilead. Saul was still at gilgal and all the people followed him trembling. He waited 7 days at the time appointed by Samuel, but Samuel did not come to gilgal. And the people were scattering from him. So Saul said, bring the burnt offering here to me, and the peace offerings, and he offered the burnt offering. As soon as he had finished offering the burnt offering behold, Samuel came and saw went out to meet him and salute him. Samuel said, what have you done? And Saul said, when I saw that the people were scattering from me and that you did not come within the day's appointed. And that the Philistines had mustered at Mick mash, I said, now the Philistines will come down upon me at gilgal, and I have not entreated the favor of the lord. So I forced myself and offered the burnt offering. In Samuel said to Saul, you have done foolishly. You have not kept the commandment of the lord your God, which he commanded you for now. The lord would have established your kingdom over Israel forever. But now your kingdom shall not continue. The lord has sought out a man after his own heart and the lord has appointed him to be prince over his people because you have not kept what the lord commanded you.

Jonathan Gilead Two Years 6000 Horsemen 7 Days 30,000 Chariots 3000 Men Jordan Saul First Bethel Hebrews Gilgal Philistines Samuel Benjamin Chapter 13 Beth Aven 2000
Joe Piscopo Describes His Amazing Journey to SNL

America First with Sebastian Gorka Podcast

02:16 min | 2 months ago

Joe Piscopo Describes His Amazing Journey to SNL

"Improv. I heard that the original cast was leaving Saturday Night Live. That's Gilda Radner. That's Chevy Chase. That's John Belushi. That's Billy Murray. My hero, Danny aykroyd. And they were looking for cast to replace the original Saturday live. And I wanted nothing to do about it. NBC did a go round of all the comedy clubs. They never picked anybody. I got a call from a friend who was writing on SNL on the new SNL. He got a writing job. He told gene dominion produced at the time. You got to see Joe Piscopo. He does impressions. I would do impressions. I was doing the Frank Sinatra president on stage. I would do Tom Snyder. Remember Tom Snyder said that day was great. And I would do all of that on the stick. So they brought me to NBC. I went up to the 17th floor. I did an in studio kind of audition for gene domain and she said, okay, you know what? We're going to put you on tape. We're going to put you on tape. Come in this date. So I bypassed a lot of auditions, but I went in, I got down to the last few hundred, and I went into what it was David Letterman studio in the 6 a, I believe it was at NBC. And I just riffed on camera. Now, I was so cocky back then. I was young number one, number two. Who wants to replace the original cast of Saturday Night Live? But I did the old man, this is Sinatra. I did all the impressions. They left. They liked it. They hired me as a utility guy. They needed somebody to do the impressions right there. They hired me. And so we went in. And if I could cut to, we did about ten shows on SNL. Gilbert Gottfried was in the cast. There was some great chemical. Billy, the gili, I came up with Gilead to comedy club. Then as we were casting the show about to mount the show on the air, I walked up to the 17th floor one day and someone said, I want you to meet a kid from Long Island comedy clubs. I was in New York City comedy clubs. We didn't know the Long Island comedy clubs at the time. I walked in and as a young kid sitting down and they said, Joe, I want you to meet Eddie Murphy. And I sat with this young kid who was 19 years old, 19 years old. And I immediately talked about connection, you were gracious enough to make the introduction. And the connect with Eddie, the laughing, we just joked around, what are we doing here? We just hit it off.

John Belushi Gilbert Gottfried Danny Aykroyd Eddie Murphy Tom Snyder NBC Billy Murray Eddie Billy Frank Sinatra Gilda Radner Chevy Chase Joe Piscopo New York City SNL Saturday Night Live 19 Years Long Island Gilead 17Th Floor
"gilead" Discussed on WCPT 820

WCPT 820

01:58 min | 7 months ago

"gilead" Discussed on WCPT 820

"Double toothpicks. Pardon my language. It's going to be giving a speech tonight on preserving democracy. Oh, really? Do you think that's a thing? In some way? You're worth doing? Okay. It's a goal. Yeah, here we go. Quote, all federal legislation. Sunsets means go out and it goes out of existence in 5 years. If the law is worth keeping, Congress will pass it again. For every 5 years, the Congress has to vote to reauthorize social security. Reauthorized, there also goes away. Would have to vote to reauthorize Medicare. We authorize veterans benefits can I just say as awful as the policies they're admitting to in public? Even the hot mic stuff is even worse, Brian Kemp caught on a hot mic saying he's open to banning contraception. How did we get here? How do we get to banning contraception? I mean, oh my God. This is why I told you to watch head meets tale, but I was just going to say this is like Gilead on steroids. You could have learned times 11 billion. I know about the Canadian resistance, and that's where we're going to go, but I watched the show. Not going. You're not going anywhere. Okay. One more protist. Very idea that a senator from Florida wants to cut social security Medicare. And by the way they don't just go away, they can cut it. They can change it, basically. Send her from Florida? Going after Medicare and social security? I tell you what, I don't know where as I say southern don't know where y'all been. Damn, boy. I tell you, look, so outrageous you might even, you might not even believe it. And again, word for word, all federal legislation, sunsets means goes away in 5 years. It's a law is worth keeping Congress can pass it again. Yeah. All right. By the way, let's skip over to

Brian Kemp Congress Medicare Gilead Florida
"gilead" Discussed on WTOP

WTOP

01:40 min | 8 months ago

"gilead" Discussed on WTOP

"Schedule your free in home estimate. A new deadlier form of fentanyl has arrived in Virginia and officials charged with stopping the state's resurgent opioid epidemic are worried. The drugs are lab made opioids known as Anita's ends and they're estimated to be several times more powerful than fentanyl. That's the opioid opioid that's responsible for three out of every four overdose deaths across the state. The Virginia department of behavioral health and development services says nita's ends have been found in a county near Lynchburg. You might not think of homecoming as a learning opportunity. It's more like fun, right? But there's going to be a health related roadshow on Howard University's campus this weekend. Talking about the HBCU roadshow. The historically black colleges universities are absolutely critical to our efforts around advancing health and black equity. Rashad Burgess is with Gilead Sciences. Both in addressing issues around health equity, social justice. As well as opportunities for talent recruitment. In all the roadshow, we'll visit 11 campuses in 9 cities this month, bringing students healthy sex education, breast cancer prevention info and the message about good jobs. There's a direct correlation between wealth and health. Genetic theater in crystal city is staging a production of Dracula. That star is a Romanian actor who has a connection to Transylvania. That was actually born in Transylvania, half an hour from the birthplace of Vlad Sebastian, who is the inspiration for the Dracula

Virginia department of behavio Rashad Burgess Anita nita Lynchburg Virginia Howard University Gilead Sciences Genetic theater breast cancer crystal city Transylvania Vlad Sebastian
"gilead" Discussed on The Readout Loud

The Readout Loud

08:32 min | 1 year ago

"gilead" Discussed on The Readout Loud

"Gilead scientists acquired the drug maker immunomedics for $21 billion. The centerpiece of that very large deal was a breast cancer drug called, which Gilead believed could be a foundational product in its oncology business. But two years later, Gilead's planned for turd alvi appears to be in some trouble. Earlier this week, the company announced results from a closely watched clinical trial involving Trudeau in women with the most common form of breast cancer. Technically, or maybe we should say statistically, the study was a success, Gilead announced that turd Elvis slowed the progression of breast cancer compared with a chemotherapy comparator, achieving the main goal of the study. However, Gilead withheld the actual results from the study, which as you'd expect, raised red flags because it suggested that fidelity's benefit for those women with breast cancer was minimal. Despite a quote unquote positive study, Gilead's stock price fell as investors sussed out that was unlikely to grow into the blockbuster cancer drug that Gilead had plans for and that that $21 billion acquisition would suggest it needed to be. So as we all know in BioTech disappointing clinical trial results are a common occurrence. But the tridel V setback is particularly painful for Gilead and a shareholders because it's one of three big deals that have gone bad under the tenure of CEO Dan O'Day since he joined Gilead in 2019. And Gilead, of course, is best known for its dominant HIV drug franchise, but more recently, the companies tried to become a major player in oncology. It paid that $21 billion to buy immunomedics and delvy to help reach that goal. But as this week's announcement showed, Gilead's cancer dreams seem far away from being realized. And guys, in many ways, this just kind of feels like deja vu all over again. They have been trying for so long to establish themselves in cancer, and each time when you get that sort of pivotal result, it falls short. Yeah, and it's fascinating because the angst around Gilead, you know, as you mentioned, they built this really, really effective and really, really lucrative, stable of treatments for HIV, and then eventually for hepatitis C and I remember circa 2013, 2014, when they were functionally printing money, then the pressure because this is the publicly traded company. So it's never about what you've done lately. It's what are you going to do? The pressure was how does this plucky BioTech underdog, even though they'd been around for like 30 years at that point, how do they become the next Pfizer the next Merck? And so obviously Gilead settled on oncology as being the field in which they would invest, but you can't or I guess what we're learning is that simply having a lot of money and a bunch of smart people doesn't really entitle you to success. So, you know, there's a lot of debate around the wisdom of the various deals that Gilead did, including this immunomedics deal most recently. But at the same time, it does kind of feel like a truism in BioTech that your expertise in in this instance virology doesn't necessarily make you an expert in waiting in oncology. Yeah, I feel like stepping back from this a little bit, you know, you see a company like Gilead, which has had so much success, like we said. But are now sort of struggling to kind of make this third act if you kind of think of the cancer business as kind of a third act of Gilead, sort of make that turn that into a success. And the company in a lot of ways is kind of stalled out. But they're not the first sort of big cap BioTech company to have this problem, like to kind of find itself at a point where it just seems to be really difficult to grow into something larger. And I think of companies like Celgene, for instance, I think Celgene had this problem where they just kind of hit a wall and then ultimately they sold themselves to Bristol-Myers Squibb. You know, again, our favorite BioTech company and this podcast by a chin is now also facing the same sort of growth problem or challenge. And it is just interesting to me that we don't see these companies kind of getting to a point where they can kind of become the next Pfizer or the next Roche or Novartis, right? They just sort of they struggle and then this becomes like this existential question of what they should be doing. Right, but at the same time, they're not still counted by people who are investing in the BioTech and pharma space as growthy BioTech companies. Like they've entered this new sphere where we tend to think about them more like pharma companies. I remember when Amgen announced that it was going to start paying dividend. It felt like this huge moment of we're not a BioTech anymore. We're a big grown-up pharma company. But Adam, you put together the revenue of the biggest BioTech companies and the biggest pharma companies and there's a really obvious gap between even the biggest BioTech companies Amgen Gilead Biogen vertex Regeneron. And the biggest pharma companies, J&J, $50 billion in pharma sales in 2021, Pfizer, which doesn't really count because of its huge COVID vaccine revenue, $81 billion, almost 40 billion of that being the COVID vaccine. But Roche almost 50 billion Novartis more than 40 billion Merck and Bristol, 49 and 46 billion, whereas the biotechs are all the biggest biotechs, Amgen and Gilead are 26 and 27 billion, and Gilead, of course, also was helped by COVID with its Remdesivir revenues. So even though they're in this different grown-up phase, they're not big pharmas either. What is it that kind of stops these companies from reaching that higher sphere? Did they just get bought before they can? That's a good question. I mean, quite often historically, they do get bought before they can. But I think what we're watching with Gilead is how difficult it is to ascend beyond that without getting bought. I mean, Gilead is probably unless things go really poorly over the next couple of years. Too big to be acquired for any of the major pharma companies, but it's also not small enough to get the kind of credit from investors and just from society that the plucky underdog BioTech company gets. And so they're in this sort of uncanny valley where they seem to just be constantly disappointing everyone, despite, again, this is a profitable business that is doing very well on its virology treatments. And as you mentioned Remdesivir, we don't talk about that much because we have oral treatments for COVID-19 now and a lot of other therapeutic interventions seem to be much more efficacious than Remdesivir, but they were first, and they made a lot of money on it. And yet the narrative around Gilead is just always seems to be one of expectation followed by disappointment. Yeah, part of it is a function of time, you know, these BioTech companies are not like they're newbies, but they haven't made maybe around as long as some of the well established pharma companies. And also just the sheer quantity of products and drugs that they sell. I mean, you look at you look at some of the big companies. Like you mentioned J&J and Pfizer and Novartis mean they're stable of medicines that they sell. It's just the list is a lot longer than some of the BioTech companies out there. Even though the BioTech companies have been very successful and have developed and approved gotten approved and launched multiple multiple drugs, but they do, like I said, it is interesting to sort of watch them their progression and obviously these are very successful companies. We're not saying that they're not. But that they do they do struggle at some point. And I sort of look at what's interesting to me as sort of the companies that are sort of coming up into that sort of big cap round. Look at it like a company like vertex, which has been obviously hugely successful with its cystic fibrosis, drug franchise. You know, there's a company that $8 billion in revenue now. And like a lot of these other companies has now searching for what will be next. What in their pipeline can be sort of that next blockbuster franchise, the next treatment that will generate billions of dollars in sales. And we're watching that same phenomenon play out, it feels like in fast forward, with Moderna, which in very recent past was in that sort of plucky underdog group of BioTech companies with a dream and quite a lot of money, but has since become a revenue generating firm..

Gilead breast cancer pharma Celgene alvi turd Elvis cancer Dan O' Pfizer HIV Novartis Myers Squibb Merck Trudeau growthy BioTech companies Amgen Roche Amgen Gilead Biogen
"gilead" Discussed on BiggerPockets Money Podcast

BiggerPockets Money Podcast

05:12 min | 1 year ago

"gilead" Discussed on BiggerPockets Money Podcast

"And of course, I invest. So dividend income and then that type of thing. And what sort of income are we talking about grand total here? Yeah, so 2021 gross income has been about $320,000 across my two businesses this year. $320,000? Yeah. Okay, so this is not such a bad idea. No, you know, I think January 2021 was like the first thing that this is going to be the year because I put out my first digital course in the beginning of January. And by the end of that month, I had made about $25,000 in the month. So I was like, okay, if this is what's going to happen, I'm only earning $10,000 a month in my 9 to 5, like there's really no reason for me to keep other than the benefits. And I just start talking to my husband, hey, honey. Here's my next crazy idea. I'm going to quit my job. I'm going to need to sign up for health benefits. How do you feel about that? And he's like, look. You haven't steered us wrong yet. So let's do this. Very awesome. And do you have a team, obviously, with all those plates spinning? And perhaps even some support that you have to do for the courses. Do you have a team that you're working with right now? Yeah, so I didn't have anyone until January. I mean, I'm sorry, June of 2020. That's when I started realizing like, wow, there's a lot of moving parts here. I am definitely burnt out and exhausted. So the first thing that I outsourced was the social media for my blog for my podcast. I'm sorry. For Gilead, it was just a constant. I mean, I was spending ten, 12 hours a day on social media, just building the brand and that's just not sustainable. So that's the first thing that I outsourced, and then podcast editor, so I do have a podcast editor who handles all of that..

Gilead
"gilead" Discussed on Breaking Biotech

Breaking Biotech

05:27 min | 1 year ago

"gilead" Discussed on Breaking Biotech

"That the objective response rate is only 64% with patients treated with plus acidity and of that 14 out of 25 were complete responders or complete responders with incomplete hematologic recovery or 56%. And then Gilead also looked at patients that were diagnosed with AML that also had a TP 53 mutation and of those 75% were complete responders. So pretty impressive dataset and we can see here if we compare the datasets between them. I mean, it's very obvious that Gilead's data data is quite a bit better when it comes to efficacy. And I would just say that we can be hopeful that the epochs of data as it matures might improve, but because of such a small patient population, I think, it might take another study before we start to see these kinds of deep responses as they recruit more patients. Gilead did a follow on data update with AML patients only. And this was presented in December of 2020. And for previously untreated AML patients that did not have a TP 53 mutation, those treated with my girl mad plus as acidity, the objective response rate was 50% or 7 out of 14 patients with complete responders being 36% or 5 out of 14 patients, one out of 14 was a CRI or 7%. And then those that were previously untreated with AML with a TP 53 mutation of judgment for sponsor is 69% or 20 out of 29, complete responders were 45% or 13 out of 29 and see our eye patients was 14% or four out of 29. So we can see here this does match what we just saw before that in the more disease burden patient population of AML, you do see less efficacy there. So I think this is something to keep in mind. It's going to be a good benchmark for us when alux oncology does start to look at those more disease burden patients that have AML..

Gilead
The Regime Being Run By Pharmaceutical Companies With Daniel Horowitz

The Charlie Kirk Show

01:51 min | 1 year ago

The Regime Being Run By Pharmaceutical Companies With Daniel Horowitz

"Daniel, and one of your pieces of my memory serves me well, I'm going to dig it up. You allude to the fact that this really is a regime that is being run by pharmaceutical companies. That this is about the small group of pharmaceutical companies that are calling the shots. Is it that sinister? Is it that diabolical Daniel or is there another explanation to this? I mean, I think it's broader than that, but certainly one of the lead ships in that armada of the system when you talk about the system, the cabal, the globalists, it's the pharmaceuticals. And I love how you call it the Fauci virus. China virus is really off message. The likely knew about it and maybe they had some involvement. This ain't the Chinese. They used Wuhan because it was offshore. This was done by UNC UNC Chapel Hill berwick, Jurassic, Fauci, and all the pharmaceuticals that were in it. By the way, fun fact, UNC Chapel Hill, which is the ground zero for the getting function of research for coronaviruses. You know that they're the ones who had Remdesivir. Gilead, somehow got ahold of it. Look it up. UNC Remdesivir. How is it that the only thing that was ever approved, which as I wrote yesterday have an article on this at the blaze NIH's own website says it causes liver toxicity and renal failure and we're seeing that with Sony patients, which is why a lot of people come in moderate moderate COVID, they should get over just like they go into the hospital with pneumonia every year. COPD, we have this treatable and they die. And it is the Remdesivir. It's one vicious cycle. So they'll look at Ivermectin C we can't use that and they're like, okay, let's say we're wrong and it's a sugar pill. But it is literally safer than Tylenol, won the Nobel Prize. Every piece of literature says is well tolerated. No one's ever had a problem. Why not try

Daniel Unc Unc Chapel Hill Berwick Unc Chapel Hill Fauci Wuhan Gilead UNC China NIH Copd Sony Pneumonia
"gilead" Discussed on The Nicole Sandler Show

The Nicole Sandler Show

08:18 min | 1 year ago

"gilead" Discussed on The Nicole Sandler Show

"Filarial do. I voted for the green party candidate. Come on all right very good by the way. But he's not gonna win if if you're not gonna win and in fact if you if you want to make this into a a prediction of who's going to win it's very simple Gavin newsom. who's going to win. I mean every single poll every day that comes out shows him winning and winning by a lot really have what it was actually a chance that he could lose. I don't know i. I mean i don't know i literally don't know but i like to think that i would have voted to recall him. Anyway but i feel confident That that The recall is going to lose. So i voted. I voted yes to recall him. I voted yesterday quote. Because he's terrible. And i don't agree with it's not a vote for gavin newsom. It is a vote for gavin newsom. He doesn't belong in office. He never belonged in office. I voted against him when he ran terrible. And i i. I will not vote for terrible candidates. And that's what we're talking about. Now we're talk. We're talking about voting. You wanna you wanna get you wanna train the democrats to be good defeat. People gavin newsom. Your mansion is the old trump yesterday turnovers worse but the democrats have to be taught that if they don't nominate good candidates the people will not vote for them. That's that's some now. I don't know if you saw it not add marquis. Put out a statement. That's getting widely circulated about how every democrat should be in favor of Getting rid of the filibuster and expanding supreme court. He did it very well. Good and you know. I've been talking to candidates all week about it. And some candidates like for example erica smith in north carolina alan grayson in florida. Some some of the candidates are coming out very very strongly x. Saying exactly the same thing that marquis the senator from massachusetts is saying but not all of them plenty mostly in fact most of the chuck schumer candidates so the ones that are favored to win. I couldn't because schumer's behind them they won't say it i mean they they will they absolutely refuse to engage. You know someone like val demings will not say that. She's for these things. She doesn't say she's against them but she won't say she's for them. Same thing all up and down the line all these conservative and status quo taibbi democrats ducking the issue. So they shouldn't be voted for. We haven't this is the primary season. We should vote for the good candidates. I agree candidates and the ones who are backing changing the filibuster or getting rid of the filibuster. Reforming the filibuster eliminating the filibuster. Whatever you wanna call and for expanding the supreme court. Those are the good candidates. The ones who won't say it. Those are the bad candidates. You want more care. Cinemas right you want joe mentions of course not but that's the choice. We have to realize that were being estimate. I agree with you on all of that. Here's the thing this i to the audience. This recall election is is a republican ploy. Here right so you're playing into their hands. I'm sorry if you want to vote out gavin. Newsom you're do it and an official election you don't give them their their ploy. Their bullshit ploy to oust the second democratic governor. What in two decades. Because they don't like the guy who's there now well elections have consequences for new someone. You'll let let let me finish new one. You'll let him serve out his term good batter indifferent. Another election is coming up in november of twenty two. That's when you vote. That's when you vote him out but to to to hold their way out but he won't if he wins. This recall which is going to win this recall. It's going to be very very very hard to get rid of him in. Twenty twenty two. He'll win again. Well then you know what then california made its bed. I'm sorry joe. Giving into the republicans. Making of that. Bad and i don't see this yes. Of course. the all republicans favor getting rid of gavin newsom. Absolutely but that this thing wouldn't have gotten on the ballot if if not for plenty of democrats and plenty of independence who nauseated by Gavin newsom. what does he that so bad he. He is a corporate democrat. Everything he does is bad and that includes things that includes not just doing things but not doing things you know. What if he has a A super majority in both in both in both houses of the legislature. What is california done everything that they tried to do. In terms of climate change and In terms of Medicare for all and all the all the really progressive issues california could pass all of them. They california's pissed none of them and jerry brown. He's another one that sucked jerry. Brown brought california out of financial ruin. No one's going to be perfect are they. I mean who would you. Who would you pick as governor. Who's gonna who would meet your criteria. Howie well for one would be Kevin daily own who ran for the. Us senate i think he's he he would be he. May i don't think he's gonna run but think he would be a great governor okay but to paraphrase donald rumsfeld you you. You have to deal with the the the candidates you're given not the candidates you wish you had no what i'm saying is that we should not support neo liberal corporate democrats i. I agree. I won't and and have had stopped doing that. After two thousand and eight. When i voted for obama. That was the last one i voted for. Well okay i. I'm going on record i completely disagree with you. And if larry elder becomes california governor california going to dianne feinstein kills over from a heart attack. When you're governor with twenty percent of the vote yes and gets half the number of votes that gavin newsom guests which is what would happen. Been even though. It's not going to happen but that say it happened. Yeah they'll in the california legislature will impeach him in two seconds who they will and then what happens. You think. They're going to let him pick. Diane feinstein's ex-senator terrific. What's her name. If diane feinstein keells over yeah not going to let him do that to allowing this fucking recall in the first place. Why didn't they get rid of that. Home i recall the people in the legislature of having these silly recalls. Why didn't they get rid of the record. Why do i wore. Why didn't they rewrite the rico. So it made some sentenced that'd be idiotic as it is. That's that's the million dollar question. Today i act or that. You're supporting now. I do anything they want. They have majorities in both houses. They can do anything they want. And yet this is happening. Why i'm going to war with these people not only that but every democrat who almost got on the ballot they the democratic establishment said to them. If you run you're dead to us you'll never be part of this party again. And there were democrats decent democrats who wanted to run and they the democratic establishment new. If a decent democrat was running that would be for newsom. Some he'd be he would have no chance to win. Then you know what then. I don't know i don't know what the answer is. Not that i have all the answers but we're just completely thoughts completely. Stop supporting conservative..

Gavin newsom erica smith marquis val demings california supreme court green party alan grayson chuck schumer taibbi schumer joe Kevin daily Newsom north carolina massachusetts gavin dianne feinstein florida jerry brown
"gilead" Discussed on The Nicole Sandler Show

The Nicole Sandler Show

07:08 min | 1 year ago

"gilead" Discussed on The Nicole Sandler Show

"Eve that election and never should have been confirmed so there are two justices in fact three three in my view who never should be on this court so we certainly need to unpack this court in order to restore any measure of competence in the impartiality in the fairness of our highest court in this country. Right and the other thing. Lisa is that we haven't mentioned. Is that mitch. Mcconnell did away with the filibuster for supreme court nominees. Now the democrats had gotten rid of it for other executive appointments. I think judicial nominations but not for the supreme court of course the minute. The republicans had control. They they did away with the filibuster for the supreme court. Making it possible that if they had control of the senate they get to confirm whatever justices they put forth. They also made it very clear that if if if obama had won reelection they would've kept that seat. I mean i'm sorry. If hillary clinton had won they would've kept that seat open. They would not have let her fill it. The lindsey graham said. It wasn't only mitch mcconnell so they you know they play these games that the old. It's okay if you're a republican. Well now you got. And i know. I'm veering off a little bit here. But joe mansion just made some noise the democrats better shut up with that three point five trillion dollar infrastructure thing. Well you know what. Joe mansion better figure out. What fucking side. He's on because i'm getting really pissed. Not that i have to say. Oh no it is. It is really outrageous what we're seeing here because what we have in affecting the i take senate minority role. We have a majority of senators representing nearly forty million more americans than the minority of those senators. Which which has led by mitch mcconnell who in my view personal view not. My organization is an torius. Liar i've seen him i People's faces when i was working in the united states. Senate he is a liar and he You know basically impose one role as you said for republicans one rule for democrats one role for republicans during elections world for democrats. He has talked about his proudest. Moment is entire. Life was blocking that seat from president. Obama stealing at who was a twice duly elected popularly elected and Winning the electoral college elected president of the united states. It was his his prerogative to fill that seat with someone like maryland who had an unblemished record of fairness of modesty on the bench. And instead mitch. Mcconnell and leonard leo and these other right wingers were so tight the right wing money start money infrastructure. We're determined to take over the supreme court to packet and not not pack it with fair people packed with people who they believed would not be fair who were chosen because they were believed that they believe that they would not be fair that they would in fact impose their personal views and imposes political agenda of the right wing republican party. And that's what we have. We have a court that is unsuited to play an independent role in our democracy. Because it's basically an arm of the far. That's right of the of the republican party and what we do from here. I mean i thought somebody forwarded me an article from the daily beast. That is blaming. Joe biden for this. The headline is joe. Biden abandoned texas women to the republican agenda. What could joe biden have done to codify roe. V wade anything. Well i mean this idea that that president abandoned texas is ridiculous. The fact is is that the republican governor greg abbott. That everything he possibly could to try to prevent texans women and men from voting in that election by having one drop off location and counties that had millions of people in the middle of the worst pandemic in in one hundred years in american history so it was republicans and they were hoping leaders of that state that had sought make it harder for the people of texas vote and to have their voices heard and to have their voices carry in the state of texas in federal elections and a state election. They've done everything. They can to gerrymander that say in order to basically preserved their minority rule and to try to prevent a democrat from winning a statewide they basically a statewide cedar even at or you know or many other seats that where they where they have any margin to kind of crush through these redistricting measures that texas has really been at the forefront of doing this This gerrymandering and so the idea of blaming biden is actually ridiculous. That's it's also the case that there should be a federal statutory Statutory right to codify roe. I would certainly support Those measures And at the same time we're dealing with a democratic party that has power in the sense of having the gals in the senate in terms of being able to gal hearings have hearings schedule hearings. But it doesn't have the power fairly to pass those because it has a few democrats like joe manchin and kristen cinema who are willing to curry favor with the chamber of commerce. Or whatever right wing group they think is kissing their ring to do their bidding instead of actually defending the principle of the democratic party. So i'm personally not organizationally but personally disgusted by what i've seen from some of these weak-kneed democrats who have failed to stand on just basic principles. A woman's right to choose the women's right heard her reproductive. Death neater own personal choice about her health. Those are fundamental aspects in my view of being a democrat in in our in our system and republicans have taken this pro-life for that isn't even articulated in the bible. There's like six hundred different edicts under the law moses. None of them. Not one of them Make any statement about abortion And the fact is that you have one party that has veered to sort of far theocratic agenda very regressive agenda and also has obviously embraced In in many ways white supremacist ideology and has also been demonstrably devoted to making it harder for americans to exercise their feeding vote. And you have another party. That has a bigger tent. And that has some individuals like like joe manchin and kristen cinema who are You know not reliable In terms of having a having enough votes to pass a good loss any laws that would make a difference in people's live right on. Nancy pelosi has said the first bill. She's going to introduce when congress comes back on september twentieth. First of all it. It will be a bill making the roe. V wade the law of the land. First of all. Why wait until september twentieth. Are we not enough of a crisis right now to bring everybody back and get on this and second of all great so it will pass the house by three boats. Maybe but then it'll die in the senate because of the filibuster and he got kirstin cinema and joe manchin standing in the way. What are we supposed to do.

senate supreme court mitch mcconnell supreme court of course joe mansion Joe mansion Mcconnell mitch texas leonard leo joe biden lindsey graham republican party obama hillary clinton united states kristen cinema Lisa greg abbott joe manchin
"gilead" Discussed on The Daily Beans

The Daily Beans

01:42 min | 1 year ago

"gilead" Discussed on The Daily Beans

"That <Speech_Female> <Advertisement> <SpeakerChange> <Speech_Music_Female> <Speech_Male> we do. You can <Speech_Female> do that by going to daily beans <Speech_Female> spot dot com <Speech_Female> and clicking on contact <Speech_Female> and thank you so <Speech_Female> much for all of <Speech_Female> your submissions. <Speech_Female> We love you this my favorite <Speech_Female> part of the day. The <Speech_Female> best he <Speech_Female> has. So that's <Speech_Female> our show <Speech_Female> for <Speech_Female> today. Do you have anything <Speech_Female> <Advertisement> you want to end <SpeakerChange> on. Amy <Speech_Music_Female> <Advertisement> <Speech_Music_Female> <Advertisement> thanks <Speech_Female> for listening <Speech_Female> in. And i hope <Speech_Female> you all have a good weekend. <Speech_Female> I'm <SpeakerChange> rainy <Speech_Female> boston. <Speech_Female> So i hope <Speech_Female> that it gets a little <Speech_Female> bit better. I'd like <Speech_Female> to speak to the manager. <Speech_Female> Because i <Speech_Female> was promised a hot girl <Speech_Female> summer. And it's just <Speech_Female> been very <SpeakerChange> wet <Speech_Female> so yeah <Speech_Female> hucker. Summers are <Speech_Female> tough in boston <Speech_Female> have you. <Speech_Female> Are you <SpeakerChange> allowed to say <Speech_Female> while you're there. Yeah <Speech_Female> i'm doing a movie. <Speech_Female> It's for <Speech_Female> <Advertisement> apple and it's a <Speech_Female> retelling of a christmas <Speech_Female> carol. But <Speech_Female> it's like you know. <Speech_Female> Like i don't <Speech_Female> know of a lobster this part <Speech_Female> but you know we'll just keep it <Speech_Female> between us Ryan <Speech_Female> reynolds is playing <Speech_Female> the scrooge <Speech_Female> and <Speech_Female> will ferrell's playing one <Speech_Female> of the ghosts of the <Speech_Female> of christmas past or <Speech_Female> whatever and it's <Speech_Female> really fun it's super <Speech_Female> just <Speech_Female> the best way <Speech_Female> to spend <Speech_Female> a summer <Speech_Female> on the <SpeakerChange> east coast <Speech_Female> if it would just operating. <Speech_Female> Yeah i think <Speech_Female> that the that kind <Speech_Female> of makes it a hot girl. <Speech_Female> Summer sort of <Speech_Female> like helps <Speech_Music_Female> helps. <Speech_Female> <SpeakerChange> <Speech_Female> Yeah i've got get <Speech_Female> caught outside and a <Speech_Female> white t shirt <Speech_Female> <Speech_Female> really <Speech_Female> hungry <SpeakerChange> all summer <Speech_Music_Female> <Speech_Male> awesome. <Speech_Female> Well that's amazing. <Speech_Female> And please tell my <Speech_Female> good friends will <Speech_Female> farrell ryan reynolds. <Speech_Female> I say hello. I will <Speech_Female> kidding. They <Speech_Female> don't have any idea who <Speech_Female> i am. <SpeakerChange> Oh i bet <Speech_Female> they do. I bet <Speech_Female> you they're probably <Speech_Female> like legume <Speech_Female> <SpeakerChange> noughties <Speech_Female> for life <Speech_Music_Female> racing. <Speech_Male> We walk in. <Speech_Male> Ferrell's got a <Speech_Male> shirt on. <Speech_Music_Male> That'd be amazing <SpeakerChange> <Speech_Female> everybody. <Speech_Female> Please take care of yourself <Speech_Female> tickets each other. Take <Speech_Female> care of the planet <SpeakerChange> and take care of your <Speech_Female> mental health. I've been ag. <Speech_Female> And i've been <Speech_Female> aimee carrero. <SpeakerChange> <Speech_Female> And them's the beans. <Speech_Female> The daily beans <Speech_Female>

"gilead" Discussed on The Daily Beans

The Daily Beans

06:55 min | 1 year ago

"gilead" Discussed on The Daily Beans

"As apple. Pie brought back a memory. The cbc canadian broadcasting corporation hosted a contest to see what the canadian equivalent was as canadian as blank. The winner was As canadian as possible under the circumstances. Oh my god that's perfect. I think that sums up being canadian to a tea. Perhaps this could be a new game as blank as blank. That would be fun if you have a country that you want to submit to as canadian as possible. Under the circumstances we would love to hear from you or a state even. Yeah absolutely now and for my pet tax. i offer you my super mutt. Doug i sent to pick of him as a giant puppy and he's almost full grown slowing down at ninety pounds the biggest goofball ever but also a handsome gentlemen when he feels like it feel free to get the breed mix hint there are four. Oh god okay well. let's. I'm not gonna look down Okay lab is german shim yes. Oh yeah Shepherd lab Rottweiler oh yeah yep probably yeah. Yeah and oh my gosh look what it looks like now. Oh definitely definitely rottweiler. And maybe boxer. Oh yeah let's see what we got. Let's see lab. Mastiff german shepherd and belgian tavern ask did That's that's what. I was seeing his roddy as the with the mass deficits. Yeah okay cool. Yeah because i guess maybe. The rottweilers are a little thinner but what a cutie being nafta look up a belgian server. And i've never heard of that. I've never heard of it all right next up from owen pronouns. He and him pronounce the town. Hello beans queens. I'm from new zealand. And i live in australia. So there are plenty of may orien- indigenous australian place names. I can throw at you. But even better the allegedly english placenames. Yes my partner who is from. La and i live near melbourne. Which of course is pronounced melbourne. Yep just up. The road is the town of guildford which is pronounced gilded in the other direction is fines for which is signs fitted and hilarious a macchi which is pronounced exactly like anarchy but without the are anna key. Hey okay anneke okay. This degree of mispronunciation. My partner insane for pentax ronin the dog and his new best friend. Jimmy chunga wanna take a guess at ronin breed. Thanks so much for using your light to brighton. So many days even as you turn light into dark places. Oh oh my oh. I'll reveal in this photo. I didn't see it until i scroll down. Oh wow look it up baby. That is a sammy pomeranian. I dunno i definitely pomerania but you imagine how small the cat is. That's the size of a pomeranian. Japanese spitz my friends. Oh wow. i've never seen japanese spitz in person or maybe have would have also i. This is crazy. I've been to australia and tim melvin. And that was like one of the first things i noticed. Because you know there's melbourne florida. Which is you know not close to where. I grew up miami but like as a place people know so i was like. Oh yeah we're in melbourne melbourne. And they're like melvin. So i'm glad to know drive someone else crazy to So cute amy's court. Don't own one case on the docket lemon v lime the wolfpack hey being spam longtime listener first-time writer. I've got a case for amy's court me and my wife had been arguing over the color of lemon lime gatorade for about a decade now with no end in sight that is until today we have a collective agreement that whatever elaine of avalon. Rules is binding yes. My is six and has watched all of the episodes. Listen i'm very very flattered. Thank you so much also. I wanna apologize for all of the earworm songs. Because i still sang and recorded them years ago so so thank you. Sorry I've seen the one with the magic dressing causing About three times. I think that one is this the one that has sister time on it. Which is a song regardless i've got the agreement between my wife and daughter. That if elena amy is willing to make a ruling on her case we shall accept it because that would be super cool. My personal stance. Is that the lemon lime. Gatorade is indeed yellow. Because you know. I have my wife and toddler on the other hand have laid claim that it is green. We've asked many friends for outside opinions but we remain dug in on our stance so for once and for all amy's court would you please make an unappealable ruing so we can continue on with our life. Okay i i really i this is this is this is oh wow now the mention it i wanna say this is a neon yellow. Yeah i it's a highlighter. Yellow i am so sorry to your wife and daughter i usually go with the gals on this one but i think it's like a highlighter yellow. I think i you know. I know they're not looking for my opinion but i'll know file it. We need it. We file an amicus brief with the court here. I do think that falls in the yellow spectrum. Yeah i really do. I also love how they did like a phone. Html what is it when you look color code. I forget they did the thing. And it's i think it's very clearly like like a dirty kind of highlight or neon yellow Yeah i don't see green because the labels green green label right. And maybe. That's why i wonder if we put it in a glass. It would be more yellow or if you look at the top photo where the label is gray and not green. Oh right oh look at that. That's true true okay. Yeah this is what my p. Looks like after i drink all my vitamins. Yeah that's what i was gonna say. It looks like vitamin enriched urine. The yes exactly what it looked like. Oh man off so sorry. I'm sorry to take a stance. And again i apologize to your wife and daughter but i think the thing. I think you might be right on this one. It is yellow all right. that is amy's decision. Thank you for writing into amy's court wolfpack. We appreciate you very very much and if you have any disputes you need settled something like this. A decades old long argument about the color of beverage. You can send the even even if you have a dispute with your cat. I have many disputes with my cat. I might have to bring one of these amy's courtroom one in we want to know but If you have anything like that or any any other things you want to add to the good news segment If you have some good news yourself for confessions all you know the whole list of stuff.

orien anna key melbourne Jimmy chunga amy tim melvin cbc nafta australia elena amy guildford Doug spitz owen apple brighton new zealand melvin La
"gilead" Discussed on The Daily Beans

The Daily Beans

03:19 min | 1 year ago

"gilead" Discussed on The Daily Beans

"Am joined by actress. Extraordinary voice over work just the most level personnel ever made in hollywood. I'm sure her name. Is aimee carrero. And if you have anything you want to admit for good news confessions corrections. Misheard song lyrics shared swears. Find the cat happy places. We have so many games. What the mutt town twisters. Louie gohmert is dumb. Limericks whatever whatever you have if you want to start a new game clearly were down so just send it to us. At daily beans pod dot com and click on contact. And that is how you will hear yourself. Read on the air. I up from anonymous amy pronoun. She and her misheard lyric kinda when i was elementary school. I thought the pledge of allegiance ended with with liver tea and justice. For all that that i spend a lot of time wondering why anyone wanted to deliver t. How liberty was provided to. All i mean man. Government sent out a box of liver teabags or was there a special liberty dispensing place and whether my parents were hogging the liberty that was supposed to be for me. Because i never had any or maybe liberty was like my dad's beer and only for grown ups. Oh man as my pet tax is paid by abbey found on adams boulevard in los angeles and the best fluffer butter. Ever look at this. Oh my god could do be those eyeballs. That's a cute little much head till with the little mohair. Flip coming over the side. I can't believe that anybody loved that. Dog our no just you know well. That's hilarious and i'm very glad it's not liberti because really i'd be out i'd be totally. Yeah i'm like. I don't want your i don't want your liberty or your democracy Okay we've got lisa pronounce. She her after a terrifying few weeks with lots of tests and hospital procedures. I found today. That i not have cervical cancer. Woo that's great news for guest the mutt. I've attached a photo of my pod. Pets ranger daisy ranger is obviously a block lab. But can you take your guess about daisy. Thank you for making me laugh. When i didn't think i could only so. I'm so happy that you got some good news. Lisa that's so great and high five. I've been cervical cancer. Free for twenty seven years so amazing high. A five to you. That's amazing amazing news. And what a load off your mind. That must be an these. I i i imagine these dogs were there for you every step of the way. Let's new be. That's a cool. I mean they're both beautiful. Ceesay is interesting. I i i still think. Dc has to have some break look at those faces. They look lab. Pity maybe healer. Oh i what is that. It's mitt makes spots. Oh this spotty dogs. And then there's probably like something sammy hitter chow chow or something. That doesn't make any sense. The chow always. Daisy is a german short haired pointer lab. Oh i should've known the german shorthair pointer. Oh my god i've never. Wow okay gotta look up a german short haired point. They also have spots. Yeah food such a lovely daegu. All right next up from adrian pronouns. She and her double ended. Dildos are as american.

aimee carrero Louie gohmert liberti cervical cancer hollywood amy Ceesay los angeles lisa Lisa chow chow sammy Daisy adrian
"gilead" Discussed on The Daily Beans

The Daily Beans

01:58 min | 1 year ago

"gilead" Discussed on The Daily Beans

"And do You know active shooter drills and this is something that every single youth of today grew up with the threat of climate and the change in the threat of a active shooter drills and they are not You know to your point. They are not patient and waiting for incremental results. They are demanding. Transformational change of our system of our government and of the systems that keep incremental incremental change in effect and they. They're saying enough is enough and frankly they are going to be the central drivers for for not only their engagement but really real movement on this Going forward. yeah and i'm with them. That whole concept of incremental change is what has us on the brink of accused climate crisis. That whole concept is what has us on the brink of losing hundreds more every week to gun violence. So it's it's not a sustainable model and i i remember and i people who listen to this. Podcast will probably stick a me talking about this. But when obama sat in the chair with with the podcast pod. Save the people right. After trump won the election. I put one in quotes but right after trump was elected and said it's the youth it's the it's the kids that are going to grow up. Become voters are going to wash over this country like a wave and that is who is going to be taking over and we need to listen to them because this is now their planet and these are their issues. So i'm glad that you all are doing work with that. It's going to be super important. Can you tell everybody tell listeners where they can find support both the aarp victory fund and the api lions. Thank you so much. So it's api victory. Fund dot com api victory alliance dot com. You can also find information on the victory. Alliance website In regards to our brand new think tank our.

trump obama aarp
"gilead" Discussed on The Daily Beans

The Daily Beans

01:40 min | 1 year ago

"gilead" Discussed on The Daily Beans

"Know these these styles of voting restrictions that they will then create law or regulations or legislation that is not fully thought out and thus will that we will have more unintended consequences later on to deal with so. That's why we absolutely need to be at the table. We're not asking to be ahead of anybody else. Our saying is that we need to be at the table with all these other civic leaders that we can work on this coalition ever. Yeah i don't think people. I think people underestimate how much also gerrymandering has has impacted the api. And i can think of several examples right here in my home district and again just you know not special not more just seat at the table. I think is not too much to ask for. But that's a really interesting point. You brought up about a new target on your back. Because i mean i i just feel unfortunately for so long that. This whole voting block is kinda been ignored. Not that i'm saying. Hey everyone pandered to a new voting block but you know i mean realistically it's such an important block. Such an import movement with all of its own considerations and and so. I think that that's sort of kind of what the victory fund and the alliance or are working toward doing especially with creating this think tank completely. I mean think about what has happened in a four year. Kemp campaign cycle. It's it's something that's never happened before that we've been able to find in the history of politics. In the united states of america we went from voting fifteen to twenty points.

Kemp united states of america
"gilead" Discussed on The Daily Beans

The Daily Beans

01:33 min | 1 year ago

"gilead" Discussed on The Daily Beans

"What the issues are. Were and who vote far. Obviously on a partisan basis so that was why the refund was formed to fill that massive gap and considering where the obviously the fastest growing population in the country We now have twenty. Three million voters seven percent of the overall population and we delivered in this last election. I know we're gonna dive into some of that in a little bit. But you know we we At the outset. Were trying to fill this major gab. We think we filled it under the correct operating premise. We still have a lot to learn about. Api voters because the amount of research polling that goes into is abysmal. We really don't know what we don't know about the community so that's what we're trying to fill. Yeah and i've noticed that the api community has been left out a lot of conversations but recently a few months back there was a large focus from biden administration and the department of justice on a violence. Hate crimes against asian american pacific islander community especially as it relates to cova and i was wondering with the steps that the administration and the department of justice have taken with regards to those hate crimes. Do you do you think what they've done for. What have they done it. Do you think do you find it sufficient to battle this because it seems now that we're not talking about it anymore and i'm curt i'm concerned and we are concerned as well. Because one might intuitively believe that the accounts of.

biden administration department of justice cova curt
"gilead" Discussed on The Daily Beans

The Daily Beans

01:54 min | 1 year ago

"gilead" Discussed on The Daily Beans

"Is a coordinated operation and we're all bearing the brunt of it and it needs to end and the best way the surest way that we can make it end because we outnumber them by a lot. This is a small vocal minority. Where very well funded possibly. Not by the way by american money. How the fucker we supposed to know. It's dark money we don't or it comes from there to report it right. I don't know who pays off the federalist society. I don't know it may be americans it may not how the hell we know if we can't be revealed who the donors are right which is also dangerous. The thing to do spread the word. The dark money needs to go. And i wish i had better news this is this has been a a really depressing day at two days between the the hurricane and afghanistan and now this allison you know she. She really gave me quite a day to take over the show. I i wish i had come on here. And and and Tell you something better but unfortunately I'm bound to what happens on the day to day you know. What can i tell you. So i think we are gonna have something fun coming up later that might brighten. Everybody's spirits usually. I'm the person on twitter who brightens everybody's spirits today. I don't feel very bright. Maybe by the time you're listening to this. I'll feel brighter. Maybe the supreme court will have done something. Maybe we'll have some sort of wakeup call. I don't know but democracies at risk and all this means is that people more people are going to die because the republicans have become a radicalized party operating against the interests of the people of the united states when we come back alison talks with the ruined the core president of the api victory fund plus a best of the good news segment. Stick around these mri. Jesus hey.

federalist society allison hurricane afghanistan twitter supreme court alison united states
"gilead" Discussed on The Daily Beans

The Daily Beans

05:40 min | 1 year ago

"gilead" Discussed on The Daily Beans

"Here. This is no different. This is this is men in positions of power imposing their will upon half the population. That's what it is a power. Grab and i wanna talk about that too because i understand this is an emotional issue for everybody in it should be. It should be because this is it. Unconscionable and the people that are doing this are awful. Awful awful people. They might think they're great but they're not. They're awful people who are imposing cruelty on a population because they think that their view of righteousness is more righteous than whatever. It really sickens me. But it's bigger than that the abortion debate such as it is is bigger than that this is going to go to the supreme court probably right. Somebody's gonna sue. It's going to go to the supreme court. Maybe the supreme court will strike it down. We hope they've done that before. But there's no guarantee and we have on that supreme court six of the nine justices on the supreme court right now. Six are radical catholics. I'm allowed to say this. Because i'm a confirmed catholic. And i'll tell you these are radical. Catholics what does that mean. There was a group of people in washington. Dc that hung out at the catholic information center. Which was the opus. Dei affiliated center there in washington run by the sky father mccloskey among the people in that group antonin scalia. Former judge right and clarence thomas. Lots of other people too you can i. I wrote a piece about this. On prevail called leo the cancer. And if you're interested in this. I encourage you to go read it. Leonard leo the titular leonard leo who has basically the brains behind the federalist society and judicial watch and all these groups that that senator sheldon whitehouse is doing a really good job trying to expose the dark money going into these into these coffers. This is a guy who went in there with his buddies and subverted our judicial system. He groomed judges to be on the court and he put them there right. So all of them. Roberts is one of these guys. Cavenaugh obviously is one of these guys. Gorsuch is one of these guys. Amy conybeare it one of these guys. She's a woman but still one of these guys and alito. That's the other one. These are all people who subscribe to this influence of this father. Mccloskey in that original group of radical catholics ultimately the vision that they have for the country is not consistent with democracy opus. Dei grew out of fascist spain. It's it's part and parcel of fascism. And what these judges are trying to do. The mindset that they all have that these dark money creatures like leonard. Leo have is to impose their idea of what should be lawful honest society even if it is not what the majority of the people want. Most people in this country are pro choice as should be so to have a system where we are not where we're going back to the stone-age medically how are we going to do that. Unless we subvert the court and tear down democracy so this is a terrible thing. It's a terrible thing for the women of texas. It's a scary thing for women all across the united states and it's also a scary thing for democracy and people who care about democracy. It's scary it's terrifying. It's abominable. And i wish that i had some better news about what we can do about it. Because i don't other than the supreme court needs to be expanded. Cavanaugh needs to be investigated. I've written apple stuff about this. Go to my twitter. Feed greg all are at g. r. e. g. o. l. e. arts pin tweet read all about brett cavanaugh and the many many laws that he broke and slimy things that he's done and how we can get rid of him from the supreme court right other than that were at the mercy of these people there are only nine supreme court justices. Six of them are these leonard. Leo radical catholic supreme court. Justice is that is not an adequate and representation of who the country is and that needs to change. We need to change it or this is just going to get worse. It's going to get more autocratic. Our rights are going to continue to erode and unfortunately the people that are going to bear the brunt of it are women people of color the lgbtq community. The people we should be protecting with the greatest force are the people that are most exposed. And that's what's so terrible. Now that's going on in texas in california we have another attempt to subvert democracy there by this recall vote. Okay gavin newsom. Look whatever you think about him. He's the democratic governor of the largest state and most important state in the country. California is a lot closer to turning red. People realize this is really important. Vote if he goes. And he's replaced by that whack. A doodle larry elder guy. It's curtains that's ballgame. Democracy is over over. Let me tell you what i'm talking about there. Let's just project this little further. Okay let's say that newsome is recalled elders now the governor and then something happens to feinstein okay. There goes the senate. Now we're fucked fucked so if you know anybody in california please lobby them to go. Vote all you gotta do is vote. No don't fill out anything else in the ballot vote. No no to the recall. Send it back super important. No pressure future. Democracy depend voting again. These things are connected. The california recall. Vote the stuff that's happening in texas. This.

supreme court leonard leo catholic information center senator sheldon whitehouse Cavenaugh Gorsuch Amy conybeare washington antonin scalia mccloskey clarence thomas leonard brett cavanaugh Mccloskey alito leo Roberts cancer Leo Cavanaugh
"gilead" Discussed on The Daily Beans

The Daily Beans

06:30 min | 1 year ago

"gilead" Discussed on The Daily Beans

"The daily beans for thursday timber. Second this is not alison. Gill ordina goldberg. They are on vacation. This is greg. I'm your host for today was also your host yesterday if you listen yesterday and today i'd like to thank you for sticking around and having faith in me to land this plane because i've been given great responsibility here. We have a wonderful show today. Let's hot notes dot notes. The only thing we're talking about today. Is this abortion ban. This draconian abortion ban in texas and the supreme court not intervening to stay the implementation of the law. This is catastrophically awful for a million different reasons. Starting with people are going to die in texas women are going to die. Disproportionate number of those will be poor people of color. They will die. Nobody texas seems to care at least in the in the top government of texas. Which is let's talk about who these people are. That are bringing these things on. I understand this is from the the texas legislature but let's look at the the leadership of the republican party in the state of texas. You have greg abbott. The governor if you've seen pictures of him you see that he's in a wheelchair the reason why he's in a wheelchair is because when he was jogging one day a tree fell and struck him on the back paralyzing him turned around and foul lawsuit against the owners of the property where the tree had fallen one some massive settlement. What did he do. He used his legal training and initiated tort reform. So that the law that he used to get that big settlement now people can't use it anymore. That's what an evil fucker is. I mean going into the job between the power grid power grab which resulted in people dying mirror. That's when ted cruz with cancun between that and the inability to deal with covet and to put the restrictions in place he's been willfully actively exacerbating the spread of cova in texas all along. I think he finally came out in favor of vaccines like a week ago. And now this is pretty clear that he is first of all a selfish asshole and second of all. He wants to kill as many people under his watch as possible. I mean that's what he's doing. We can only judge a man by his actions and that's what. His actions reveal his number. Two dan patrick in the state of texas. The lieutenant governor actually has more power than the the governor for some reason. I'm not really sure why this is the guy that went on. Tv last year during the pandemic and lobbied for the state to reopen. saying i'm paraphrasing. But it was close to this. We need to be willing to sacrifice our elders to help the economy. So that's who that asshole is. And he of course has been lockstep with abbott. In these policies that have resulted in people of texas dying at greater rates than they should. And then you have the attorney. General paxton who is under indictment has been under a diamond for four or five years for like fraud. That's who's in charge there. These are evil men. I there's no nice way to say they're evil men now. What's interesting to me is that i hate when people try to point out the hypocrisy with this stuff because it's so easy to do but the same kind of people get riled up about masks. I can't wear my mask. You're impinging on my freedom. They're totally fine with this. Repressive taliban ask abortion ban which is going to result in people dying and women and children dying and in great numbers. It's also gonna it's it's they're throwing a monkey wrench into the medical system into the healthcare system right now because now people i guess can be sued because you know if they do anything that suggests abortions so you have. Doctors and providers can be sued. What they think is going to happen here. People are gonna leave. The state is what's gonna happen. There's going to be a brain. It's going to be devastating. And i think that's by design. I mean i can't it. It boggles the mind right. I remember reading years ago. About ron paul. His great libertarian. Ron paul also from texas. Of course ron pau. Libertarianism is great. government shouldn't have any power. i don't want the government my business except for abortions than the government's okay. Then it's okay for the government to step in in a medical decision between woman and her doctor. Then it's fine. None that makes any sense. It's rank hypocrisy. That's all that it is right in the thing is what really makes me mad about this. In addition to the the cruelty and the the amount of energy that this is going to suck up from people. That should be working on things that we you know that we don't have to working backwards at this point is what i'm saying. This is what i'm trying to say. We shouldn't have to worry about this at this point at this stage in the game any argument that is quote unquote. Pro-life is dumb. I'm just going to say it right here if you don't like it too bad if you don't want to get an abortion. Hey here's what you do. Don't get an abortion but to create a law that prevents other people from doing something that's medically necessary. That's a decision that a doctor. A trained medical professional advises a patient to do. How is that like thing. Because why. because you're too dumb to understand biology and how the body works. You believe that. Disinformation campaign about all life begins at conception. It doesn't even the ancients didn't think that anyway we could go on and on. There is no good argument to be pro-life there is none the only arguments that people make our religious in nature and religion should have no basis at all in the way that we govern ourselves. That's pretty basic. I mean we were in war in afghanistan partly because we didn't like the fact that the taliban wanted to declare sharia law there right. They treated the women badly. They treated the lgbtq badly. Well we can't protect our women.

texas Gill ordina goldberg ted cruz greg abbott General paxton texas legislature alison dan patrick cova republican party greg supreme court ron pau ron paul abbott taliban government afghanistan
Why God Wants Us to Be United in Christ

Pray the Word with David Platt

02:00 min | 2 years ago

Why God Wants Us to Be United in Christ

"Judges chapter twelve verse. Four then jeb. The gathered all the men of gilead and fought with f frame and the men of gilead struck f frame because they said you are fugitives of f. Renew gilead i'ts in the midst of ephraim and manasseh. Read this verse. Because it's a concise summary of civil war. Among god's people in this point in the book of judges god's people are turning against each other and are fighting against each other in ways that are obviously destructive for them and ultimately dishonoring displeasing to god. And we see this picture and judges and then we read the rest of the bible and we see this tendency over and over and over again. And it's all over the new testament church even as i've been preaching through. First corinthians of spin reminded of divisions among god's people and tendencies among god's people to turn against one another i think about jesus prayer for us is god's people before he went to the cross like this is the one thing. He was praying for us as he transitions in john. Seventeen to praying for those. Who would believe in him through the witness of his original disciples and he praised that we be one just as he and the father are one. And so it's it's pretty clear what god desires for us as his people

Gilead JEB Manasseh Ephraim John
"gilead" Discussed on The Iron Fist and the Velvet Glove

The Iron Fist and the Velvet Glove

03:11 min | 2 years ago

"gilead" Discussed on The Iron Fist and the Velvet Glove

"What could we just buying great. It's entirely up to you as you view it as to you and i think that's true. Actually what other sort of preconceived ideas you might have when you it. You sort of take on board as you. Look at the strange thing pull. Did you have any thoughts about the same as you saw in. I wasn't actually aware of until maybe you made me aware of it. I came. I mean it wasn't something i'd come across in the news. And just thought it was sub. Treville has to be hardly worthy of comment right. I wanted to think this is such a big deal. I i just thought it was amazing decision making to have that troop doing that in that situation. I just thought it was a strange juxtaposition of little things happening Anyway the rauch taste is that psychological tests where people showing like ink blots and they Are asked to look at the ink block and once you see and then some people might say a butterfly and other people might see an evil demon or whatever and it's sort of a way of looking at how people respond to it. Maybe being more honest about themselves when they look at the impact anyway. That's what i can see two angels who are ready to join the noosa satanic. Actually you're right looking at that particular inc. I see like a moth or of lie type thing. But you're right. It could be to angels vice. Want how they managed to couch. My parents fighting so vivid. That i can't so that was just strange number one and Mill says a bad as the collisions milkshake consent video. And that's what we're on next mill. Well so we had this. We've had a lot of issues talk lightly about consent in how we need to educate people perhaps on what consent is and this amazing video that came out and i'm going to play you some of the audio so you can you can hear listen It's a sane whereby szekely sort of light teenage couple sitting down with a milkshake. So i'll just play some of that now..

Treville two angels Mill one couple
How Jenny Lorenzo Became the Internets Favorite Cuban Abuela

Latina to Latina

05:18 min | 2 years ago

How Jenny Lorenzo Became the Internets Favorite Cuban Abuela

"Jenny. I'm almost have to admit not accustomed to seeing you as jenny. nobody else. Is that what you look like. I want to take a listen to the first video that you ever did. Hold up today. Go to pick up one three gilead of better sex for three going on meeting me gomez day metal supplement. Okay iressa on. And off for the love of god. So here's what's interesting. It's the first video that willa was ever featured in for buzzfeed but she insisted prior channel of mine called aggressive comex and a boiler was first introduced as a superhero Because this was a channel that was predominantly white male audience. I talked about video games and comic books and movies. Sifi strictly me being nerd and then at some point i did a movie review of the film kick ass and me and my writing partner for the show was to the cuban well because he knew that i kind of already did that sort of thing and so it was the same terrible wig that you do see in that buzzfeed video i think i through like baby powder on it to make gray and she had like this painted red mask over her eyes with like a fly swatter as were weapon and then eventually it made no sense for the channel. But you can tell that. I yearned to make this sort of content. It is interesting that something that is as big as a bulla takes that many iterations to get there like. I think there's a lesson in there for any creative. That is not necessarily that. The opening gambit is where you land now never being a nerd is as much a part of your identity and culture as being cuban. It seems did you see characters on tv or in media. Who has a latino nerd you identified with not really wasn't until recently that i started seeing that representation especially in a show like no spooky because these are a bunch of latino gods that are into the macab and they're a bunch of nerds and outsiders because that's a big part of me to what most approximated your own experience i would say. A lot of that was in black television. You see urkel you see. Carlton banks a lot of these like nerdy people of color on tv. Maybe sometimes says from that seventies show me. He had like a bit of a nerdy flair to him. I feel like latinos on tina's specifically were usually depicted as like very sensual loud colorful. You know things sofia vergara in modern family that was the typical depiction of what was and. So that's why. I had a hard time in the audition room. I didn't fit any mold of what especially miami casting paint a picture for me of what auditioning in miami looked like. It was a nightmare for me. I would show up and for those who don't know me. I'm like five feet pasty skinny little shits and he but then i have this like deep voice. No one knows what to do with me. So then i shopped to these auditions and they were usually little late sorta lottery or like colgate but then i would be up against women my age but they looked like supermodels and then there was me so then i just never felt like. I was sexy in us to sell toothpaste. I remember my very very first universal casting audition. It was for the florida lottery. And i had to be like this sexy. You're even an award. These like plastic clear stripper heels. I don't know. I don't know what i was thinking but i was nineteen years old. The silver lining of this terrible experience is that emotive issue to become a creator. I was tired of this. I was so tired. And then i did a couple extra work. Gigs was extra on. Burn notice and dexter. And guess what. I was scantily clad and tacky his hell because that's what they thought of people in miami. All of these shows always depicted people from miami in the same way and it always took place in south beaten always involve drugs and sex and violence. Which is another reason why. I'm working so hard today. To eventually sollers show. That depicts miami in a more authentic way so yeah it pushed me to go to school and learn how to do everything else on my own.

Sifi Jenny Willa Gomez Miami Sofia Vergara Carlton Tina Florida Dexter
ASH 2020 Update

Breaking Biotech

05:21 min | 2 years ago

ASH 2020 Update

"So. I'm excited we back and we have a lot to get into and the reason for this is that we heard a number of from the american society for hematology conference. That just took place a couple of weeks ago. So we're going to talk about updates from trillium therapeutics tgi therapeutics actinium. Pharma and i wanna do a little bit of a follow on to my video about anna back with regards to their parkinson's disease data so we're going to touch on all of this stuff and Overall is a pretty interesting conference from some of the data. Updates that i saw of course i'm just going to focus on the companies that i'm interested in but then i'm gonna follow it up with a few other updates that we saw that led to huge increases in in their stock price. So have a lot to get into. So i'm just going to get right into it. And i think before we talk about the company's specifically i did just wanna talk a little bit about non-hodgkin's lymphoma and the reason for this is that to companies trillium in focus a lot on this disease and i just want everybody to be up to speed. So i've talked about non-hodgkin's lymphoma in the past. And i showed like a version of this slide. But i've included a few like prices of previously approved drugs for these diseases just so that we all have a bit more context on what we can expect in terms of a proper valuation for the companies. So just we all understand. Non-hodgkin's lymphoma characterizes a group of malignant lymphocytes cancers. These are known as he malignancies and lymphocytes as we know at their b or t cells and these are part of the adaptive immune system. They collect mutations such that they can grow and then deposit in different areas of your body leading to non lymphoma so they're characterized based on where the lymphocytes and of depositing also whether or not they're indolent or aggressive so the inland version are very slow growing. And they're not always emergency such that they don't need to be treated necessarily immediately but they need to be monitored so the decision to treat with any of the different treatments that event lined here is really up to the doctor themself. Now when it comes to aggressive versions of non hodgkin's lymphoma there's obviously more of a drive to treat and to get rid of this cancer because it's leading to significant side effects on the patient so just to give a little bit more context here the prevalence of non hodgkin's lymphoma and this is the all of them. So i'm just including all of them in this calculation it's around twenty cases per one hundred thousand adults and this is around seventy seven thousand patients in the usa per year so it's a significant patient population treatments out there. That exist are pretty numerous. Though so there's chemotherapies immune therapies targeted therapies. And then i also put radiation stem cell transplants. And then just to give a little bit of a description on the different one. So for indolent non hodgkin's lymphoma. Cdl small lymphocytic leukemia lymphoma marginal zone. Lymphoma cutaneous t. cell lymphoma so that would be on the skin now. All of these cancers have been aggressive version. So if the indolent version gets more aggressive it would turn into these types of cancers that include p tcl deal mantle cell lymphoma or burkitt lymphoma. So keep all that in mind. And i did just wanna put here. So i'm showing a chart from various corporate presentation on Talk about them but just to sort of frame What we can expect in terms of objective response rate of what we want some of the approved drugs already. They hit ours in the range of twenty to thirty percent and then the drugs that verizon was looking at they did a little bit better. But when we're looking at whether or not therapy is is good or bad. You need a reference to compare it to so depending on where they are in terms of the line of treatment. They're looking at and the mechanism of action in the side effects. If they can garner in objective response rate of twenty thirty percent in general that is seen as decent or approvable at least for the fda now it comes to price this is also pretty critical because when we're looking at understanding the total value or potential value of a company. We really have to look at the potential addressable market so drugs that have originally like longtime ago been approved for different types of non hodgkin's lymphoma reduction was one of the original ones and right now it's approved for first line non-hodgkin's lymphoma and i didn't get into the details because they do specific indications but generally a course of this treatment for four months costs around thirty nine thousand dollars so that's kind of the the floor and then there's another one here that's approved for second line or greater see. Tcl cost around twenty nine thousand per month in this zelina but then this can go all the way up to. Yes carta which is approved for third-liner deal as a gilead drug and the cost for that is three hundred seventy three thousand dollars per treatment course so there's a big range and the total addressable market for the entirety of non hodgkin's lymphoma is around three point two billion dollars. So you have to think of all of the approved therapies that are out there and if companies are going to try and get drugs on the market you know how much of that three point two billion are. They going to be able to get for their specific drug.

Hodgkin's Lymphoma American Society For Hematolog Trillium Therapeutics Parkinson's Disease Malignant Lymphocytes Cancers Lymphoma Cancers Lymphocytic Leukemia Lymphoma Pharma Cell Lymphoma Burkitt Lymphoma Anna USA Verizon FDA TCL
Gilead's revenue rises 17% driven by sales of coronavirus treatment remdesivir

Bloomberg Daybreak: Asia

00:12 sec | 2 years ago

Gilead's revenue rises 17% driven by sales of coronavirus treatment remdesivir

"Gilead Science has reported a revenue jump of 17% that was driven in large part by sales of the code. 19 treatment room disappear. Even so, Kelly had chairs right now down about

Gilead Science Kelly
Covid: US gives full approval for antiviral Remdesivir drug

Balance of Power

01:40 min | 2 years ago

Covid: US gives full approval for antiviral Remdesivir drug

"A Corona virus being a vaccine being available by year end. And yesterday, the FDA of granted its first approval for a treatment, not a vaccine, but a treatment room disappear to Gillian. Scarlett Foods here with some of the details, and, of course, from disappear is one of the treatments that President Trump was given. After he was diagnosed. We saw Gilead Sciences, the company gap higher at the open, rising as much as 4.9%. This is a drug that was originally developed to treat Ebola, and it's now become the first covert drug to get FDA formal approval before that it was available. Under emergency used authorization. So Gilly, I can now move forward with marketing the drug, The new brand name will be victory. I'm not sure why they're changing in. There must be something more to that. But given that everyone knows that, as from disappear, it's a bit of a puzzle to me. Gillian had said it would charge US hospitals about $3100 for most patients now in terms of the numbers, analysts estimate 2020 sales will be about $2.2 billion. Cos. Expected to sell 1.5 million doses this year. One blockbuster drug, of course, can make a huge difference for biotech firm and Gillian will need it because it's getting a lower return from its research and development. Then some of its peers only 40% versus a 42% at Vertex and Bio Marin. Now the FDA approved and disappear for emergency used back on May 1st. But if you look at the stock price, it actually hasn't done that. Well. It's fallen about 23%. Sadie Group says that Gilead has first mover advantage. But that only goes so far because The drug will provide a short term boost for revenue. But sales were actually taper off in the second half, when there's more competition from vaccines and anybody treatments are in development right now make so much the scarlet food for that

FDA Gillian Gilead Sciences President Trump Scarlett Foods United States Ebola Gilly Bio Marin Gilead Sadie Group
Mirati to Rival Amgen in Solid Tumors

Breaking Biotech

08:10 min | 2 years ago

Mirati to Rival Amgen in Solid Tumors

"So to start I wanNA talk about exact sciences ticker symbol e x a s, and they are now trading at around twelve billion dollar market cap, and what they announced is liquid biopsy testing data in six different cancer types showing a sensitivity of eighty six percent and a specificity of ninety five percent, and they did kind of a grab bag of cancer types. We have lung ovarian, liver pancreatic, and Alpha Jill. And so I did video on exact sciences quite a while ago I thought their evaluation was a little bit toppy back then and was waiting for dipped to buy, and that's what I did during the Cova crisis I took a small position and then I sold just recently at around ninety four and I think is trading just over one hundred dollars right now but this. Is Nice to see them kind of moving into new areas because I think one of the things that they're struggling with is leaning on their old testing kit the colours guard while all these other companies are trying to get into things like liquid biopsy, which it's going to be a real game changer in the space. Once these treatments get validated and approved by the FDA. Now. They're not alone doing this exact sciences is kind of just finally getting into this because other big players like alumina through grail they just acquired this private company called grail officially officially. We've garden health personalisation of been floating around and invitations. Well, who just acquired archer DSL there's a lot of companies in the space, but exact scientists has shown some pretty good success in their previous testing kits. So it just makes sense them to jump into this new area and be a good competitor. So I think right now probably a little bit toppy with the price around one hundred but I'm pretty pleased with the small profit. I made given the number shares that I have. So that's exact sciences. Want to move now into regeneration ticker symbol. And they're trading at a sixty billion dollar market CAP. I did a video on them also a few months ago, looking at kind of their staples in terms of the different products that they offer and I concluded that they were relatively over-valued back. Then I think now also a little bit overvalued, but it does depend on how well their product. So and the kind of revenue they can bring in obviously but the news that we heard is that they released data on their antibody cocktail for covid nineteen. and. What we saw is that it reduced viral loads and symptoms versus placebo in non. Patients who are infected with SARS co to and what they shared our results from initial cohort of two hundred and seventy five patients, and they also have nine hundred or more patients enrolled. So this is kind of a preliminary analysis that they're showing US and they've called it a phase one, two, three trials. So they're doing the PK the safety along with the efficacy and other sorts of secondary outcomes all at once and when I look through their stuff, they started off by kind of categorizing patients based. On Sarah Negative or zero positive and I, think it's important that they do this because we're looking at a treatment for covid nineteen and if people are already sero-positive in their bodies, already mounted an antibody response in order to bring down viral loads. So what regeneration is trying to pose here is that the negative patients which means they have not mount that antibody response have significantly higher viral load and they make a better target for most treatments probably also their antibody cocktail that they're gonNA share data with. So. Then the data that they show here shows a range of efficacy based off of viral load. So we have tended the power of four copies, parallel all the way to tend to the seven copies personnel. So quite a big range in viral load here and I just blew this up on the screen. What we're seeing is that at the higher viral load, the treatment and there two different doses here in the green and the red line, we see that much more dramatic decrease in the amount of viral load in. These patients and it does kind of make sense because if your body's already mounted an antibody response, the window of efficacy is just going to be a bit smaller than if it's before the at which your body's manning response. So I think for these patients, it's definitely positive data. They also looked at other other metrics as well and I'm not going to get into everything but they did look at a day to alleviation of symptoms and they looked at the overall population of patients. It's the difference of nine with Placebo. To between six and eight, depending on the dose that they gave the antibody cocktail with the negative group alone, the placebo was thirteen days and then the low and high dose was six and eight respectively. So obviously a big difference when it comes to whether or not the patient is zero negative or positive. So that's probably going to inform the FDA when it comes to approving the drug or giving some kind of guidance on which patients should take the drug and who are likely to see more positive outcomes from that. So overall. I think it's good. It gets a step ahead of the Gilead data where I don't think we've even seen a placebo group yet. So it's nice to see regenerate actually do this placebo controlled trial. We can see whether or not there is efficacy and I, look forward to seeing the rest of the data I'm not if this merits taking a position regenerate here given that they're such a large company already and they have so many different assets that are I would say more likely to contribute to their bottom line. This doesn't entice me to take a position, but it's nice to see that we're getting all these therapies are starting to see vaccine data, and this just makes me feel better in general that we're going to move towards being able to treat this disease and hopefully get out from under this and then Kinda recover with the economy. With that, let's talk about the main story for today, and that is morality Therapeutics Ticker Symbol M rt ex, and they're trading at a price of one sixty, two point zero five per share giving them a market cap of seven point two, billion dollars. Their Q. Two, twenty, twenty, net loss was eighty, three, million dollars, and this represents an eighty percent increase year over year there their q two net current cash is six, hundred million dollars giving them a runway of about until twenty twenty two I would say but let's also be careful that if they see positive data. This year or next year is a good chance that they're going to raise again. And what Morad is trying to do is develop targeted cancer treatments and they're specifically looking at solid tumors and even more specific than that are K. Rasa inhibitors, and so they have to compounds Marta six, eight, four, nine, and x, one, three, three. They're also looking at checkpoint inhibitor resistance with their compound sicher Vance it, and I'll talk about that in a bit later. To start though we gotta talk about chaos and the reason why this is so important is that chaos mutations are present in a large population of cancer patients. The first thing it's important to note is that chaos is pretty ubiquitous. It's a critical part of the map kinase signaling pathway, and this is very important in basically every single cell. This pathways involved in Cell Proliferation Cell Survival had differentiation here. There's a whole bunch of other stuff and it makes a little bit confusing because it is involved in. So many different pathways that if you were just to inhibit this molecule non specifically, you're likely to see significant side effects with patients. It's for this reason that it's important that we can come up with a targeted therapy that will only target cells that have a mutation in chaos rather than the healthy normal. KS. To talk a little bit more about its function, it works as a GT as and what this means is that it takes a molecule GDP converts it to GDP using that phosphate group to continue the signaling pathway. The next step is Raff or something like that mutations in. A company twenty, one point, six percent of all human cancers, and then I have here that chaos the predominant or exclusive Rask's mutated in three of the top four neoplasms that account for cancer deaths in the US lung colon and pancreatic. Cancer.

FDA United States Cancer Alpha Jill Sarah Negative KS Raff Rask Manning Gilead Solid Tumors Morad Marta
Trump receiving remdesivir antiviral drug as part of experimental treatment

Weekend Edition Saturday

00:50 sec | 2 years ago

Trump receiving remdesivir antiviral drug as part of experimental treatment

"Trump's physicians as the president is being treated with room to severe. NPR's Joe Palka reports. That's a drug usually reserved for hospitalized Covad 19 patients who are quite ill. Rendez severe, is an antiviral drug made by Gilead Sciences. It's administered intravenously, typically to hospitalize patients for five days, 10 days for sicker patients. So far, the best medical evidence suggests the drug reduces hospital stays by about four days. It's not clear if it prevents deaths from Cove in 19. An expert panel, convened by the National Institutes of Health concluded there are insufficient data to recommend either for or against the use of ram best severe in patients with mild or moderate cove in 19. The president also received an experimental monoclonal antibody therapy made by the company. Regeneron

President Trump Joe Palka Gilead Sciences Cove National Institutes Of Health Donald Trump NPR
The Obviously-Going-To-Die Stocks

MarketFoolery

19:19 min | 2 years ago

The Obviously-Going-To-Die Stocks

"We're going to start with the stock of the day. Don't call it a comeback bed bath and beyond has been here for years. It's just all that time someone else was running the company but now that Mark Trittin has been in the Corner Office for about a year. We're seeing days like today second quarter profits came in exponentially higher than expected. Same store sales were positive for the first time in four years. The stock is up more than thirty percent this morning. I'm assuming at least part of what we're seeing with the stock is some shortsellers saying that's it. I. Think. I'm. Probably. Bed, bath, and congratulations to march written and Beth by best buy bed bath and beyond. For this quarter, March, written formerly of target, of course, and a few other places before that, I think Nordstrom's and I believe. He had a stint at Nike to could be misquoting. This bed bath and beyond is in a group of companies retailers that I like to call the obvious obviously going to die crowd. And the funny thing about companies that are obviously going to die when they get the right mix of management decision making and in some help from the environment and you know just a little bit of because no one's more aware of a company's struggles at least no one should be more aware of a company struggles then the people inside the company. And that's when you plan your strategy. What are our tools? How can we navigate our way through whatever we found ourselves in business is not easy and certainly for this group retailers that I'm Gonna I'm GONNA hold up. Bed Bath and beyond as one Chris. But you know how about Game Stop Game Stop. The seller of video game systems and Software that of course is going to be the next blockbuster. Right if they writing that headline since two thousand and nine, how `Bout Michael's the craft store everybody knows I. Y has an Amazon run over. And the granddaddy of all of these. Companies that are obviously going to fail. They're obviously going to be taken bricks and mortar is dead is best buy which just before the podcast we were talking about how? How many listeners? Realize, that best buy has been at ten bagger over the past decade they went through some struggles they brought in new management. WHO had a plan? and. I'm sure they were mocked and I'm sure people were skeptical and they executed on that plan and best buy, which was a sub twelve dollar stock in. Two Thousand Ten two thousand eleven is today roughly one hundred twenty dollars stock. And so when you see. I'm a kick myself a little bit on dust by iron best buy bed bath and beyond his too many bees. Bed Bath and beyond. I actually did a little bit of work about a year ago as I was discussing with one of our with one of our foolish coworkers. About this basket of Taylor's who are sure to die. And we had this one. We had game stop we have Michael on the docket and I went through you know what this company's history of cash flow was and what they've done with it and how they've raise capital, and this is before Mr Trenton came on but I. It laid the groundwork for someone with. A better vision to come in and knocked the ball out of the park which you've seen today and and best bed bath, and beyond is as we speak it's now a six th bagger since March of this year and so in the a roughly a year ago when I did my work because I was vigorously debating co I pointed out that in the previous six years here was bed bath and beyond had produced four point two, billion dollars in free cash flow. They had also issued one point five billion dollars in debt and debated smart about the debt because the debts. Basically staggered I think is a ten twenty and thirty years. and. They have to pay it back anytime soon, and they had gone on a massive buyback program. They've they've retired a ton of their shares. Now. Slowly melting ice cube no one's going to want to own this business what have you. But at the time the stock was about ten eleven dollars the company is training but four times enterprise value of free cash flow. that. That is rock bottom fools that is something that is going to go away. That's what the market is telling you. Flash, forward, to today and oh positive cops. Oh. We have a plant. They've they've suspended their dividend they've they've halted their. They've halted their. They suspended the dividend halted their share buyback plan I believe in. April. But with this. With this. report, they have generated a ton of cash flow. They've deployed it smartly they took down some temporary which they had out as part of the PARCO vid. They have bought back twenty percent of that long dated not in any danger to come calling debt they bought that back at a discount. Which is brilliant. They. So they're down to their down net debt down by about thirty percent from where they started the year. They have a store optimization program, which is something that a lot of these retailers the slowly melting ice cube crowd will call them. They are reducing their store count 'cause they don't need it because they can move to ECOMMERCE, which they've done a little bit they can move to. The geography is able he served by less stores and you see a lot of. Traffic that previously went through one store transitions to another and. They are steal a Ron grosses them here they are firing on all cylinders and I'm not sure. Anyone. Thought is coming. I am I am both thrilled that they are doing this they're having success because everyone loves a comeback. I'm less thrilled that you own it and I don't. But. That's mainly because I had this in my hand a year ago Chris and I'm holding it up. The skull of York. And and I'm looking at it and I didn't at least put a little field position because as I said, at the time training for four times free cash flow that is close to no-brainer territory for me. So two other quick data points before we go to our next story. Not. Surprisingly digital sales of big driver this quarter. That goes hand in hand with the store closures so Another smart move by Trittin and his team. And also Happy to see that they're you know suspending the dividend that they're. Suspending the sticking with the we're not going to buy back shares. I'm also happy to see they're not offering guidance. Their New Orleans. No need to at this point. Let's move on the third quarter sales, for Pepsi, grew five percent and. Kind of like we saw three months ago snacks and some of the beverages particularly the Seltzer. Part of their portfolio helping to make up for the fact that somebody restaurants are closed. So many sports and entertainment venues are closed and. That's that's the stock is basically flat and this kind of flat for all of twenty twenty but. Nice to see that the the salty snack part of the business is making up for the sort of the tried and true Pepsi part of the business. Gilead household particularly the soon to be sixteen year. Old Member of the Gillies household has been doing his part to. To to help with the salty snacks portion and shareholders. Thank him. Yeah I was GONNA? Say. You know dude. There are other food groups other than Doritos. Look it was a perfectly acceptable boring quarter from a perfectly acceptable boring company and and I think you know Chris but maybe some of the listeners not know. For, me to call a company perfectly boring from for me. That's a compliment because I like businesses that are boring. Not Terribly exciting person myself I enjoy. Investments in companies that just actually do what we expect them to do, and essentially just get it done quarter after quarter. Pepsi is not GonNa. You know if you'RE LOOKING FOR PEPSI TO BE A. Ten bagger. You know anytime soon like the aforementioned by we mentioned earlier. That's not gonNA happen. They are just a steady bedrock performer for your portfolio and we all need a few of those. So we can go after the more exciting things in our portfolio. Yes. So it was it was A. It was a boring it was a boring quarter but boring is nice because boring boring says, oh, we end up four four plus percent on. Organic revenue growth total revenue growth went up five plus percent. EPS Is up ten percent year-over-year just for the quarter. It's still down for year to date, but of course, Mindy Stan why because the previous quarter? Cova. no-one no-one was new what was going on? So we kind forgive that. They are they're pointing towards the full year. They did give guidance their point point to a full year of approximately four percent revenue growth approximately five fifty core earnings. Stocks at about one hundred, forty bucks. So it's not cheap. But it's not terribly expensive, and again, this is one of those widows and orphans stocks. You can buy put it away and we'll see you when you retire. Hugh Johnston, who's the CFO at Pepsi? Granular on CNBC this morning talking about because when you think about all of the food and beverages they have across their portfolio he got granular talking about the new cheetos macaroni and cheese saying you know they're trying to keep up with demand as a fan of both cheetahs and macaroni and cheese I haven't tried it yet but I can see why it's popular. Any. Do they give any color on the? Two. Portals that they were direct to consumer sites that they launched earlier this year snacks dot com and Pantry shop dot com. Sadly, Chris they did not at least in the conference call or the press the presser maybe in the ten Q I haven't read the ten q yet obviously but. Yeah no snacks dot com I can confirm both of those sites are open and accepting offers as of this moment. SNACKS DOT COM and Pantry shop I think is an interesting one because they are. You know you are buying your you're you're buying all of your Pepsi Slash quaker products. Simultaneously in in in the various groups. So if you want your everyday Pantry, you want to get your your oatmeal and your healthy. Your healthy Chia bars and your rice cakes do people still eat rice cakes and if so why? You can get all those delivered at the same time or your snack package your breakfast package You know it's it's interesting to to have it delivered. I I'M NOT A. I I'm one of the three people in North America is still doing own grocery shopping. So I'm probably target here but I know a lot about the people how to use it and I think probably if I let my as I mentioned a sixteen year old note that this thing existed. It might be his only source of nourishment. So yeah, don't don't. On, the first time I went to that website I kind of went crazy to the point where in the box showed up to two days later even my kids were just like. This is a lot of snacks and was like, yeah I may have ordered too many but but I regret nothing. Playboy. Enterprises is returning to the public markets after nearly a decade and because I was are out of fashion, playboy is going to be doing this through a speck. Mountain Crest acquisition is a current special purpose acquisition company that is going to be taking playboy public through a reverse merger and wants to deal is done that company where the ticker is MC. ABC? Is. The playboy name and the ticker symbol P L B Y? I guess I, I saw this story and I thought, okay I'd that's one way for playboy, which is a private company and has been since twenty eleven. I. Guess That's one way to raise money. I, I, I'm hard pressed though to think that. The second round of playboy being a public company is going to go any better for the company and for investors than it did the first time around. That was my initial take as well, and you say it's one way to raise money I'd say it's one way for insiders to cash out. Tomato Tomato. The more I think about this though. I could be spectacularly wrong and it wouldn't be the first time. This might be quite this might be interesting I can see. I can see a number of thing, and I just find this interesting from a number of re. I as you point out. Yes, playboy. Is private the SPEC the Special Purpose Acquisition Company Mountain Crest Acquisition, company. It's out there. Now it's got. It's a walking wallet got a bunch of cash their stocks over ten dollars specs go at ten bucks. There's nothing you can. You can go buy today Chris if you want. And You can just sit there and wait until the transaction is completed in q one. If. You WANNA own playboy. So, playboy today is not playboy of the past for thing, magazines have died. So, there are no issues of the iconic famous magazine. These no regularly published issues and I believe they went to quarterly publishing versus. Monthly publishing before that. So what playboy is trying to be or this new iteration trying to be a licensing company and they're calling it across four major categories they're saying sexual wellness, which I'm just going to skip to the next one, which is style and apparel which is. Apparel. and accessories for men and women globally gaming and lifestyle also digital gaming hospitality and spirits. So you can get yourself some playboy-branded Bourbon. And beauty and grooming, which is fragrance skin care grooming cosmetics for men and women. Okay. That sounds interesting. They're not a publishing company more avoiding that and I guess they have a bunch of online stuff as well which. Tell people they can go look on their spare time but. They are calling themselves a streamlined high growth business. The company has four hundred million in cash flow contract through the next eighteen years. and has products available for sale and in ten thousand major retail stores. In the US, this is a brandon company. Now, now, what you think of the brand and what you associate with the brand, the iconic a bunny ears brand, of course. Is Is. is going to be probably a nuanced and varied. I can understand why some people. Would not want to do with this brand I completely understand that is not. Bend the most shall we say progressive brand in history? It has fostered some. Attitudes, particularly women that. I think it's fair to say some would find distasteful and I I completely understand why? And for those people, they're just not going to be shareholders and that's that's fine. But what I find interesting about this if this, if the licensing deal and we have, we've already had a certain dry run of this in. Do you know the magazine Maxim? It was. So it's a men's lifestyle magazine, girly pictures, and whatever it was bought by an entity called big holdings. I'm going to say eight nine years ago. With the goal of they went into change it from the the lad magazine into more of a lifestyle brand licensing deal what playboys doing. Now. I mentioned earlier it's important to have You know leaders businesses, you respect and trust big lorry holdings is not one of those businesses but I do know that they even though they're circulation sales are down significantly there they have turned that profitable on a small scale with the licensing strategy. I suspect the playboy will do a better job. And It will depend on the valuation coming out but you know when analogy I might throw up as. As a comparison is. Franchising businesses in the in the restaurant space. So a restaurant brands international, which owns importance and Burger King. Dunkin brands, which of course owns your beloved Dunkin donuts. Those are those are check cashing businesses, they they sell the franchise to a Franchisee. And then take tax six percent of their gross sales and royalties every month plus x percent for advertising they sell you a system and so those are very asset light cash-rich capital Genita- businesses. And part of me wonders here it's obviously not the same as selling. Coffee and whatever. But part of me wonders if that is what this business will look like, and if they are truly in the growth business and the cash generation business, this might be an interesting opportunity. And you just hit on what I think is the most interesting thing to watch. Once it becomes a public entity again, the high growth aspect of this because now we're going to see Now, we're GONNA see through quarterly reports. Okay. Are you growing? Because that's one of those things where we investors and the market in general get to decide what we consider to be high growth And I again I had I had your initial take which was. Oh please. Like if it didn't work the first time. It's going to work less well this time. The more I read about like. I'M GONNA keep an eye on this. Curiosity. Jim Gillies always talking to you. Thanks for being here.

Playboy Chris Pepsi Mark Trittin Jim Gillies Michael Mountain Crest Acquisition Nordstrom Nike Beth Corner Office North America Amazon United States Taylor Hugh Johnston Cnbc
Merck to Invest $1 Billion in Seattle Genetics

Bloomberg Surveillance

00:54 sec | 2 years ago

Merck to Invest $1 Billion in Seattle Genetics

"Which is more than doubled up 106%. This company makes the cancer drug traditional V had accepted a $21 billion takeover offer from Gilead Sciences now tried. L ve won. US clears in April to treat triple negative breast cancer and immuno medics plans to seek broader approval later this year. You've also got Merc moving into breast cancer treatments as well. A Seattle genetics up 9% after Merck agreed to invest a billion dollars in the drugmaker. At $200 a share as 33% higher than last week's close. The purchase is part of a Siri's of deals worth as much as $4.5 billion for two breast cancer drives, and indeed one of them Treats triple negative breast cancer, so you'll have a competition to Gillian A. Merc in that segment of the drug industry varieties is up.

Gillian A. Merc United States Gilead Sciences Siri Merck Seattle
Evofem To Launch On-Demand Contraceptive

Breaking Biotech

05:16 min | 3 years ago

Evofem To Launch On-Demand Contraceptive

"Today we're GonNa talk about a company that is trying to commercialize a female contraceptive and the company's called Yvo FEM and their product is called sexy and it's going to be launched actually in the next few days. So I wanNA talk about them as the main story, and then we're going to start with some updates from Gilead O'Donnell as well as bio Merrin and actually we got some news from Amarin today that I'm GonNa touch on just very very briefly because I haven't. Totally incorporated it into my portfolio yet, but we did see some dramatic news from them. So with that, let's get going and the first thing I want to talk about is the Gilead, news that we heard and what we found out is that they were issued a complete response letter for the approval of Phil God's Nib, which was their treatment for rheumatoid arthritis. So, this is a bit of a surprise I would say and Phil God was going to be something that replaces revenue streams that are slowly starting to fall off a patent for Gilliat and they're gonNA start to feel that in the form of loss of revenue and forgotten it was kind of shoe into get approved by the FDA issued them this complete response letter saying that they will not approve the drug unless certain conditions are met and usually when companies receive Sierra L. either it's unconditional in the sense that they don't have any recourse or it has conditions on it and hear what we. Found out that the FDA wanted more data from their face, three Manta and Manta Ray studies before completing its reviewed, the NBA and they're specifically concerned about issues in male sex organs. So Gilead is going to have to provide this data, the FDA before they will approve it, and it looks like from what I looked very briefly on the clinical trials dot Gov site is that the primary completion date isn't until early twenty, twenty one where they final completion date of twenty, twenty four. Now Juliette is pre savvy. So I feel like they'll be able to eventually overcome these hurdles once they provide some data. So I. don't see it being long long-term hindrance of the company, but we've seen the stock get hammered pretty hard since the glory days of remedy severe and in general has been kind of slow to adopt new therapies to their pipeline in order to maintain that growth that people expect. So hopefully, with the approval of Fil gone, they'll be able to replace those drugs that are falling off of patent and be able to maintain their value that way. But personally no position for me from Gilead but I thought it was interesting to point this APP. Nasr Company. I WanNa talk about is by Merrin, and they are trading at a fourteen billion dollar market cap now, and they were also issued a complete response letter for Rock Avian and this was their hemophilia, a gene therapy and I've touched on Hemophilia A and. A number of different videos but I haven't touched the topic in a while. I did notice the CRO though and it's interesting because the conditions that the FDA wanted in order to approve the drug was evidence from two years of data for its ongoing phase three trial to support the durability of the gene therapy. So this is obviously kind of rough for the company because the bar is rarely set this high for other companies that two year window of therapy is going to be maintained. This has me questioning the gene therapy space as a whole that you know other companies that have invested in say route Jenex bio if they're going to have to show two years of data to show that it is a Gerbil effect, this obviously plays into the models and delays the time at which it's GonNa take for them to get revenue. So kind of. makes. Me Nervous about the gene therapy space but you know different diseases seem to have different thresholds for what the FDA wants and it's tough to predict. So thought it was worth bringing up and just for those who are actually following by man, their last phase three patient will complete two years of follow up in November twenty, twenty, one, serve you're expecting revenue from this drug. Now you're GonNa have to wait until twenty, twenty two proudly see any revenue. So that's a disappointment even though the drug does help us significant number of patients. All right. Moving on I WANNA touch on otani therapeutics ticker symbol od T, and they're trading now at around five hundred, seventy, four, million dollar market cap for those that don't remember I, touched on this a while ago they were short candidate that I had once I seemed like they had a run up in the stock for no obvious reason, and then I sold it off in anticipation of run up to this event that we just saw news to, and they're commercializing a tax seen that is given orally. So right now has to be given IV in a lot of complications surrounding that a lot of hurdles that patients he'd go through to get this. Treatment and it's Kinda tedious. So if he can come up with an oral version, it would be much better for patients and that's what Oh Donald Trump do here. So what we heard is that their face three contessa trial achieved primary endpoint and what they were looking at is test attacks will their drug plus bean compared to just capital being alone, and the results showed that the progression free survival was significantly better in the tax will plus Kapustin group rather than just cap aside to being alone nine point eight months versus six point nine months with a hazard ratio of zero point seven to just pretty good and value point zero, zero three.

FDA Nasr Company Phil God Gilead O'donnell Merrin Donald Trump Amarin Manta Ray NBA Juliette FIL Kapustin Group Gilliat
Dow Jumps As Gilead Says Remdesivir Coronavirus Treatment Reduces Risk Of Death

Bloomberg Businessweek

00:30 sec | 3 years ago

Dow Jumps As Gilead Says Remdesivir Coronavirus Treatment Reduces Risk Of Death

"That laid Corona virus fears in the stock averages gained 2/3 to nearly 1.5%. The Dow rose 369 the NASDAQ 70 to another record close at 10,006 17. Yes and Pete gaining 33. Those gains followed an analysis of Gilead sciences drug round death severe, which indicates it may have reduced deaths of Corona virus patients by 62%. Dude sent Gillian shares 2% higher and allowed investors to ignore another record increase in cases of the disease. Facebook has been

Gilead Sciences Facebook Gillian Pete
BioNTech aims to seek approval for Covid-19 vaccine by year End

Curtis Sliwa

00:16 sec | 3 years ago

BioNTech aims to seek approval for Covid-19 vaccine by year End

"Biotech partner Beyond Tech said it'll be ready to seek approval for its Corona virus vaccine by the end of the year. The company tells The Wall Street Journal. Several 100 million doses could be produced even before it's approved. Another drug company, Gilead says tests

Beyond Tech The Wall Street Journal Gilead Partner
Gilead's remdesivir will cost $3,120 for private insurance

AP 24 Hour News

00:44 sec | 3 years ago

Gilead's remdesivir will cost $3,120 for private insurance

"Has helped reduce the effects of Copan, 19 and some patients will cost thousands from desert here has been shown to shore in the recovery time for seriously ill Cove it 19 patients maker Gilead Sciences says a typical treatment course will cost people under government health programs and the U. S and other rich nations. About $2300. It will be roughly 3100 for those with private insurance in setting the price. Gilead CEO says it had to focus on wide access to the drug and not solely on value to patients. But the cost is being criticized by a consumer group who calls it an outrage and buy a Cleveland clinic doctor who says he'd prefer the government take over production and distributed for free.

Gilead Sciences Copan CEO Cleveland U. S
Gilead's coronavirus treatment remdesivir will cost $3,120 for patients with private insurance

Morning News with Manda Factor and Gregg Hersholt

00:24 sec | 3 years ago

Gilead's coronavirus treatment remdesivir will cost $3,120 for patients with private insurance

"A drug that has been shown to shorten recovery time for severely ill covert patients. Says it's quite a charge $2340 for a typical treatment course for people covered by government health programs in this country. Gilead Sciences announcing the price today for rendez severe. And says the price would be $3120 for patients with private insurance. The

Gilead Sciences
Gilead prices coronavirus drug at $2,340 for rich countries

AP News Radio

00:47 sec | 3 years ago

Gilead prices coronavirus drug at $2,340 for rich countries

"The first drug proven to show a benefit in the corona virus pandemic now has a price tag when disappear has been shown to shorten the recovery time for seriously ill Colby dying teen patients maker Gilead sciences says a typical treatment course will cost people under government health programs in the U. S. and other rich nations about twenty three hundred dollars it'll be roughly thirty one hundred for those with private insurance in setting the price Gilead CEO says it had to focus on a wide access to the drug and not solely on the value to patients but the cost is being criticized by a consumer group who calls it an outrage and by a Cleveland Clinic doctor who says he preferred the government take over production and distributed for free Sager made Ghani Washington

Colby Gilead Sciences Gilead Ceo Sager Ghani Washington Cleveland Clinic