8 Burst results for "Gerontology Biological Sciences"

"gerontology biological sciences" Discussed on The goop Podcast

The goop Podcast

14:17 min | 1 year ago

"gerontology biological sciences" Discussed on The goop Podcast

"The power to change the way we see the world. Today is no exception a letter lease fill you in on her extraordinary guest. All right over to Elise Walter. Longo is fasting and longevity researcher the the NFL Jones professor of Gerontology Biological Sciences at the University of Southern California and the author of the Longevity Diet. He also developed pro lawn a fasting fasting mimicking diet. That is pretty popular here at group. While I've gotten to chat with vaulter Longo on the podcast before at our last in group health wellness summit got to sit down with him again and really drill in to all the components of fasting. And what's the most effective form of it long ago about sixteen eight hour fasting five to fasting costing and the fasting mimicking diet. He broke down the science behind it all the research which is fascinating. We talked about a tough G. biohacking fasting may be beneficial official for preventing diseases of aging much more. I think it's important to be well nourished but try to get as close as possible to the audio weight eaten and take your time. Doing this is.

vaulter Longo Elise Walter Gerontology Biological Science University of Southern Califor researcher NFL Jones professor official
"gerontology biological sciences" Discussed on Medicine, We're Still Practicing

Medicine, We're Still Practicing

14:13 min | 1 year ago

"gerontology biological sciences" Discussed on Medicine, We're Still Practicing

"Welcome to medicine. We're still practicing. I'm Bill Curtis and today we have quite data show first of all I'm really excited to introduce Janice O'Leary the executive editor at Rob Report as a matter of fact. She built the Robb the report health and Wellness Division. Janice Nice to have you here. Thanks for having me of course my co host of medicine. We're still practicing the triple board. CERTIFIED DOCTOR OF INTERNAL IT'll medicine pulmonary disease in critical care my very good friend Dr Steven Taback. How you doing Steve Two okay? Nice to see you nice to be here and now now our special guest Dr Vaulter Longo originally planned to be a rock musician. But luckily for us he became an international rockstar doctor. In the field of longevity evident nutrition Volker is a professor and director of Gerontology Biological Sciences at the longevity institute at the University of Southern California and he's also the director of longevity and cancer programs at the Institute of Molecular Oncology in Milan. Italy a little over a year ago Time magazine. Gene named DR Congo one of the fifty most influential people in healthcare for his work on forty two international clinical studies and groundbreaking research on the fasting mimicking diets. Away to read your body of well. A mutated cells while rejuvenating are healthy ones. He's the creator creator of the five day fasting mimicking.

Janice Nice Dr Vaulter Longo Janice O'Leary Dr Steven Taback director Institute of Molecular Oncolog Gene Bill Curtis Rob Report Steve Two Gerontology Biological Science DR Congo University of Southern Califor Wellness Division professor and director executive editor Time magazine Milan Robb Italy
Valter Longo, PhD - Nutrition, Fasting Mimicking Diets, Regeneration and Longevity

Medicine, We're Still Practicing

07:38 min | 1 year ago

Valter Longo, PhD - Nutrition, Fasting Mimicking Diets, Regeneration and Longevity

"Dr Vaulter Longo originally planned to be a rock musician. But luckily for us he became an international rockstar doctor. In the field of longevity evident nutrition Volker is a professor and director of Gerontology Biological Sciences at the longevity institute at the University of Southern California and he's also the director of longevity and cancer programs at the Institute of Molecular Oncology in Milan. Italy a little over a year ago Time magazine. Gene named DR Congo one of the fifty most influential people in healthcare for his work on forty two international clinical studies and groundbreaking research on the fasting mimicking diets. Away to read your body of well. A mutated cells while rejuvenating are healthy ones. He's the creator creator of the five day fasting mimicking Diet and the author of the international bestselling book the longevity. I I was nineteen. I think when I started working on aging and At the time it was a music student in Texas University of North Texas. FAMOUS JESSICA CESCO. Obviously it was in my head all along because I did not think about what I had to do. I say I have to study aging and I always thought what an incredible challenge bald scientifically but also taught. Why is every doctor working? and He seems to me and like that's where the problem is So yeah so I. I have to say beside the years very early years. I I've always worked on this that's that's all I've ever then. Because I had read about you that you had initially wanted to be a rockstar. I started the same way my my initial thought was to be a Rockstar Rockstar. And then I realized that I was lacking one key ingredient and that was talent So I quickly switched to something that I felt I could do better and you still involved in music. It's a little bit more now I think in the You know fundraising levels over thinking of doing some some cancer onset or something like that to raise money for research. Yeah so I always Worth an aging. Since the early nineties was like enough to be a student of Roy while for Ucla was a pathologist there and it was my first mentor new at the time. The the world Most well known person working on calorie restriction and the longevity and saw I followed up on his on his he's working and So for the best Twenty seven years. We've been focusing on other. Take this old idea of station fiction and make it make it a newer idea that can be brought to the clinics all over the world so so Dr Longo. You've been looking into various diseases that are related to aging That I guess are anti longevity Diseases such as cancer and and auto immunity and cardiovascular disease obesity and how these diseases might be affected and possibly even untreated with a modification of Diet and With intermittent fasting. Yes so what we really focusing. Because he now is What I call the longevity program and and and saw a mouse Has It on. DVD program that is it's about two and a half years long Into I ran. The lifespan is two two and a half years but this the health span is maybe one and a half years of mice started developing cancer maybe after one and a half years out of the two and a half years lifespan so then the idea. Da is why is it that people don't get cancer in most cases until they're forty or fifty or older So there is clearly Did the possibility of getting cancer is under the control of this program. So what we're really talking about here are cells that have kind of an aging problem. Yeah that's what we're going after we're going to have to the fundamental changes in cells And in the collection of south that eventually will lead to dysfunction. What does the Diet that you are proposing that has been shown to have these immune modulating effects and the longevity? Well let me just interrupt for a second here You know I think we're talking about two different kinds of diets there's one there's the Intermittent Diet that you would do three times a year optimally on. But then there's your daily diet so can you comment on each of those we did Epidemiological study using the CDC database. A few years ago. Oh where we showed that Americans eight the highest level since they had About seventy five percents increase risk of overall mortality about three to four fold increased risk for developing cancer Compared to those that had the lowest protein intake so this is about you know out you eat every day and Now this was true only up to sixty five so if you When when the CDC asked the question two eight year-olds There was no longer true. In fact people eight year old were reporting. Having a law protein intake did not do very well So Oh you know this is really important that To understand that this is not we liked to have simple answers like low protein high-protein. This is good this this is bad. It doesn't work like that. It's a complex environment. You just have to learn how to navigate it and and it's not you know once you learn and you have the right physician or or or or Dietitian helping you. I think is fairly straightforward but there are a lot of data that says that high fat diet has an increased risk of colon cancer and breast cancer Animal fats and high protein seems to be Bought associated with increased mortality increased risk for Cancer increased risk for cardiovascular disease the ideal everyday diet seems to be a fish plus plus Vegan Diet That is you. We know high nourishment and low protein Then the fast moving the festival making that is really something very different. And it's not even intermittent in nature. Can you describe the intricacies of the fasting mimicking diet. What does it entail? Yeah so the fast making diet is is a law sugar. A high fat good fats are low. Protein colorist diet and fats. By that you mean Omega three versus Omega Six. Then what are you referring to good fats. I refer to Type of fats. That are associated. Will Jerry the And health span extension so the the olive oil plant plant based of a certain kind that the is for example Avocado as an daas thus far not been associated with longevity extension but Not have and so as olive oil So those yeah that's what we're focusing on the ones that provide the fats the certain type of fats but also that are being consistently associated with higher health status in longevity

Cancer Dr Vaulter Longo CDC Time Magazine Professor And Director Milan Italy University Of Southern Califor Omega Six Volker Jessica Cesco Gerontology Biological Science Institute Of Molecular Oncolog Gene Texas University Of North Texa Dr Congo Director ROY Jerry Ucla
"gerontology biological sciences" Discussed on The Wellness Mama Podcast

The Wellness Mama Podcast

07:13 min | 2 years ago

"gerontology biological sciences" Discussed on The Wellness Mama Podcast

"The. Bobby podcast. This episode is sponsored by just thrive. Probiotics. I found this company. Win searching for the most research back and affective probiotic available. And I was blown away at the difference. I found in their products they offer to cornerstone products that are both clinically studied. And highly effective. The first is there probiotic which has been studied to help with leaky gut and to survive up to one thousand times as much as other products. Whereas the beneficial organisms in something like rape yogurt. For instance, the difference is they're spore base strains work completely differently than other types of probiotics. They're probiotic is vegan dairy free histamine free, non GMO and has made without soy theory sugar salt corn, tree nuts or gluten. So it safe for practically everyone, I even sprinkle it in my kids food or bake it into products because it can survive at really high temperatures there probiotic contains. Patented strain called bacillus indicates h you thirty six which produces antioxidants in the digestive system where they can be easily absorbed by the body. Their other product is a K two dash seven, and this is a nutrient. You may have heard of it's known as activator ex super nutrient that Weston a price a dentist known primarily for his theories on the relationship between nutrition good, health development or house bound he founded this is prevalent and foods in the healthiest communities in the world. The K two from just drive is the only pharmaceutical grade all natural supplement with published safety studies like the probiotic it is also gluten dairy soy, not an GMO free and Besser both taken with food. So I keep both on my kitchen table. Here's a tip to my dad has trouble remembering to take supplements. So he actually taped these to his pepper shaker because he uses that at practically every meal and now they're on his daily supplement list as well. You can check. Out all their products. And learn more by going to thrive probiotic dot com. Forward slash wellness, mama and using the code wellness mama fifteen to save fifteen percent. So again that's thrive. Probiotic T H R I V E P R O B I O T. I C dot com forward slash my and the code wellness mama fifteen to save fifteen percent. This episode is brought to you by Alatorre naturals skincare. You guys loved the founder ADI when he came on this podcast to talk about his own healing journey after a tragic accident caused massive scarring on his face from this experience. He developed some some of the most potent and affective natural skin care options from serums and mask and a lot of products between the results are super visible on his perfectly clear skin that is free of scars. I personally love the mask, and I use it. A couple times week and often use their gold serum at night to nourish my skin while I sleep all of their products have super clean ingredients. And they really work India's absolutely dedicated to creating the highest quality products possible. And it shows you can check them out at Alatorre naturals dot com. Forward slash wellness, mama and use a discount comb wellness to get twenty percents off. So again, that's Alatorre naturals. So a l t u. You are a an AT U R A L S dot com. Forward slash wellness, mama and the discount code wellness to save twenty percent. Hello and welcome. To the wellness podcast. I'm Katie from oldest dot com. And I am so excited about today's guest because I wanted to interview Dr Walter Longo for years and in this episode, we go deep on fasting, and especially the fasting mimicking diet, which he has pioneered research on DR Congo is the director of the lung jeopardy institute and professor of gerontology biological sciences at the university of southern California. He has made tremendous contributions in research related to lunge Eddie aging fasting and metabolic disease. He is the inventor of the fasting mimicking diet, which was granted the only patents in healthcare on promoted longevity and health span and on treating diabetes. So to say he is qualified would be vast understatement. It's a tremendous honor to have him here. And I can't wait to share this interview with you, DR Congo. Welcome. And thanks for being here or thanks for every mean, I have. Wanted to chat with you probably for years. I've read your book, and I think also several of your research papers and love what you're doing to help advance the field of longevity and all of your work related to fasting and the fasting mimicking diet, and I find there seems to be a lot of misinformation out there when it comes to fasting especially now that it has started to really gain popularity and you are indisputably one of the top experts in the world on this topic. So to start off can you walk us through some of the high level effects and meta Vitz of fasting in general. So I usually start by saying that fasting doesn't mean anything and it's like saying eating, right? And so there are many many different things that you can eat and in. So we usually don't use the word eatings eating good for your not in. So the same is true for fasting. So the the will we be focusing on is what we call the realistic fasting fasting mimicking diets and the older. I think very popular forms of fasting are alternate fasting in which essentially people don't eat dividend today. And then some gold sixteen aid or timelessly eating feeding in which the period in which people don't eat is extended to anywhere from twelve to sixteen hours per day ended his house on another one called five two in which usually people at will have maybe around five hundred calories to this week for two this week five hundred calories instead of the normal number of calories. Saw. So those are the major ones now that are that are positive negatives about all of them in. I think it's very important that we move away, but the would would fasting because it's so powerful in very is similar to to medicine or. Certainly has kind of a powerful effect. And so I think we need to start describing exactly what we talking about in. What is it going to be used for or not so festive making diets we moved away from what it only fasting for number reason in the mostly our compliance in safety. So to to ask somebody to be say three four five days or a week on a water. Only fast thing issue only be done in a clinical setting with doctors that are specialized. So we end even then it's not clear that that's beneficial. Saw

DR Congo Alatorre naturals Alatorre Bobby histamine rape India Weston Besser metabolic disease Dr Walter Longo founder E P R O Eddie university of southern Califor lung jeopardy institute professor
"gerontology biological sciences" Discussed on The Rich Roll Podcast

The Rich Roll Podcast

03:43 min | 2 years ago

"gerontology biological sciences" Discussed on The Rich Roll Podcast

"That's why I call the yoga yoga Jain means hail or praise or victory. And it's a great three letter word that you beautiful for branding. Right. It's good. So I had this whole vision. And my home is called Gye John house, and it was yoga, and we were doing these retreats. And then I was doing giant virement? I was designing people spaces, and we had a community that would come and sink. You're on in our teepees called jibe. So we had the whole thing we had the whole thing. And it was good. It was really good. And in like, a good idea. Good good intention, and yet in order to really be the way showers that we were meant to be we were to mature. There was too much personal ambition in there, and I always refer to Derrick zoo. Lander is like. We wanna make a school for kids who can't read good. But the problem is we haven't really gone through the Elke. We hadn't really gotten real. We were still wanting it for a different reason, we weren't totally empty. We weren't really totally empty because there were still some wounds or some image or some things that we were trying to achieve for that reason. And so we had a beautiful sacred wedding on our land. It was magnificent one of the most beautiful days of my life. So gorgeous we had bog on does doing of vague fire ceremony. We had gospel singers. We had channels we had African wedding singers. My boys were adorable and walk me down the aisle. We were on our land. And it was truly just a joyous. Joyous day. And on that day, we we activated the initiation that would lead us through the fall and allow us to Risa so many of us in this room are being faced with challenges. We have very serious things that are going on in life. I don't know all the details. But I just know because we have a collective group of around fifty people. So within that there's going to be a whole sort of array of things, and so what we can offer. You is that you can't get away from life's challenges. You can't you can't avoid whatever your life plan is for. For you. But what you can do is you can shift the lens, and you can meet it in a different way. So again, we have all heard people say, it's not what happens to you. But who do you become in the face of what happens to you? And mostly every time that something's happening to us. We can't imagine that are higher soul would have chosen this for us. We're just kind of like what the fuck. Are. You kidding me? Like, this is not what I want. What how is this happening? Right. But if you shift the way, you come to it, and you view it as a spiritual test or an initiation, and you refined your emotional reaction to it, your judgment, your labels of what you attached to it. You will find that? You can transform it. Okay, next. We have one of the world's leading scientific thirties on the subject of longevity. Dr vaulter Longo vaulter is an expert in gerontology biological science as well as the director of the longevity institute and the program on long Jovian cancer at I f in Milan is the author of an extraordinary book called the longevity diet urge to read and episode three sixty seven we sat down to.

Gye John house Dr vaulter Longo Derrick zoo Lander Milan director
"gerontology biological sciences" Discussed on KQED Radio

KQED Radio

06:27 min | 2 years ago

"gerontology biological sciences" Discussed on KQED Radio

"But. That that seems to have been associated with one of the worst or the worst epidemic in obesity in history in the United States. So I think this five meals a day idea is a bad idea. Let me mention your book if I can't walk through long long goes book is called the longevity diet and his his record longevity institute at USC, founder of create cures dot org. This diet of yours. I mean, there's kale chips, and there's a viscous tea, and there's a lot of things that one one author said sounded like in terms of the benefits like steak oil three hundred dollar mail order kit that essentially prevents cancer and diabetes and increases the aging process. Even I think you're acknowledging that it may sound on the face of it like a bit like snake oil. But you've got washes is a distortion of the article written by forget what what newspaper. But you know. Absolutely. I mean what I mentioned earlier signs like snake? All right. If you think about these are these are thirty years start is a monkey's eliminating diabetes, reducing cancer and call in cardiovascular disease by fifty percent. It sounds like snake oil. But it's it's it's real then makes you skinnier, right? I mean, that's that's essentially what you're saying. It it also makes you thinner. Yeah. It makes you much dinner. Of course, the Monkees were very thin. And and so it's it's a reality. So people shouldn't CDs Neko, but it's a reality is a mentioned for calorie stick, Sean that, you know, in decades, it came with not much of an improvement in lifespan in the monkeys. Right. So the question is are we get as I mentioned earlier are we get all these incredible benefits, which are already a reality without the problems. For example, one of the problems is immunosuppression, so the immune system, if you have these long-term calorie restriction can become weaker the wound healing can become weaker. This is what we've been trying to do with these periodic fasting mimicking diet is to say what if you do five days only three times a year or four times a year. What effects does that have? And are there side effects? And this is why we're we're following long-term. Thousands of people and thousands of doctors that are falling people. And you know, we don't have all the answers yet. But we're getting there. And and so I just hope that people don't walk away with is negative view of these wards fascinating because happened before and that's just a bad idea conceded that almost every religion has head fasting incorporated into it. You know, whether it was Christians or Muslims or Buddhists and in India Christian. Group. Actually, I've got a caller here. Dr Longo who I believe is a Muslim who's talking about fasting from his experienced teric. Join us here on the air. Good morning. Very interesting discussion yet as a as a Muslim fast thirty days out of the year. And that can that means depending on the season how far Muslims living from the equator could be a painting from twelve hours to fourteen hours per day. And I've seen anecdotally the evidence for myself, I can speak to that. But I'm just wondering as a as a population of one point two one point three billion people wouldn't that be a source of data for your researchers for personally, I've got into the month where I start with a slight cold. And I think oh great. It's gonna get worse because I'm fasting. Obviously to me to me, it seemed. That would get more sick. And then it would have to stop the rules preclude. Anybody was sick Nick medicine. So, but then I I have always happened two or three times in my lifetime. Fifty I've always gotten better almost within within a twenty four to forty eight hour period. So again, that's my question to your tier researcher. Can can we study the populations out there can you use? In fact, I think I believe DR Congo. You come from a village in Italy where there are a lot of centenarians that also might be a good pool to look for study. But I'm thinking about the listener's question, you have all these Muslims. Can you look at for that matter Buddhist is you say Christians who fast juice fast on Yom Kippur? Maybe look at these populations in terms of the overall effects. Yes. Oh, absolutely looking. Why defining my book is the fifth pillar monitoring centenarians or population out there doing this on their own the problem? I think with the the fast in the Muslim fasting is lots of people are now over eating and night. So they fascinating today by the overeat and saw that. It causes a problem because in the in the old times there was not the case meaning you will fast during the day, and then you'll have still a somewhat calorific meal. But now that is no longer practice by the great majority of the Muslims. And so it would be difficult. And there's lots of studies actually under Moslem in some studies the weight gain during during Ramadan. When I'm looking at a comment from a listener named Chandra who says I practice the Hindu tradition academic see where I fast completely till sundown. No water as well. I feel very energetic the next day and look forward to necessarily a lot of testimony along these lines Jimmy Kimmel fasts if you like the popular culture verdict Cumberbatch fast Plato and Socrates fasted, and yet what about the side effects, and how do we measure longevity and get to the clinical data and so forth. Those are big questions that remain. We'll go to more of your calls and emails when we return here reminder of Valter Longo with us, professor gerontology, biological sciences at USC, and the director of the UFC longevity institute his book is called the longevity diet, Dr Jason Agata here in studio with us clinical fellow in pediatrics are UCSF Benny of children's hospital in San Francisco when we let me read. One more comment. Do I have time. Well, here's John. Yeah. Who says fasting two or three days a week at six hundred calories for me from on a fast day is the most successful intrusive method. I have ever tried and for anyone who drinks alcohol, not drinking two or three days. A week is certainly that idea. We'll.

Valter Longo USC United States Monkees immunosuppression epidemic obesity founder Jimmy Kimmel DR Congo Sean Dr Jason Agata UFC San Francisco researcher UCSF Benny clinical fellow Chandra
"gerontology biological sciences" Discussed on KQED Radio

KQED Radio

12:29 min | 2 years ago

"gerontology biological sciences" Discussed on KQED Radio

"And by the listeners of cake. Mostly cloudy skies today with showers off and on throughout the day. We'll have highs from the upper fifty s to the mid sixty s along with north westerly winds. It'll become south easterly later from ten to fifteen miles per hour. Sacramento today. We'll have a high of fifty nine degrees here in San Francisco. It'll reach sixty one Oakland can expect a high of sixty three degrees, Mountain View, and San Jose will both have a high of sixty four forum. I'm Michael Krasny. Intermittent fasting is gaining attention with followers of diets like the five to plan crediting calories calorie restrictions with increased energy smaller waistlines and better overall health and some in Silicon Valley say fasting leads to higher productivity. We're going to hear about the newest research on fasting including possible long term benefits side effects and dangers, and we're joined by Valter Longo. He's a professor in gerontology biological sciences. At US's also director of the USC longevity institute and author of the longevity. Diet. Welcome to the program. Professor longo. Good to have you. Thanks, very mean. We also have Jason the gotta here in studio with us as a clinical fellow in pediatrics at UCSF Benny off children's hospital here in San Francisco. Welcome. Thank you very much for having me. Good to have you as well. And voltage lingo Longo. Let me begin with you. And let's begin by talking about intermittent fasting. What is perhaps wise would become so popular? Intermittent fasting refers to a few different methods and one of them is what's called timers to defeating. So for example in for eight hours fasting for sixteen or alternate day. Fast and easy one day. Not the older or Sunday called the fight to you have about five hundred calories. Two times a week. And then that will we been studying which is periodic fasting actually something that you do maybe three or four times a year. And you're saying that not only could you lose weight, but you can get health benefits from this based on research. Yes, you can get benefits, and you can get problems, you know, and intermittent fasting. I I don't like that word. I never liked it. Because it just it's like saying eating, it doesn't really mean anything. So we need to separate the good from the bad. Like we've seen for calorie restriction. That's something that has been around for a hundred years and really relates to just eating less all the time. We see lots of benefits and lots of problems, and I think by just doing things like intermittent fasting using words like that. We're going to end up in the same place. Lots of benefits lots of problems the list talk about the benefits I have in your body can shift actually from fasting from essentially storing fat burning it, right? Well, actually, most people don't understand that takes longer than those most of this intermittent fasting take Knicks that I've described in entail. Saw usually it takes two to three days for the body to fully switch to Akita genyk mode and the emotional dogs don't even get near there. So you must cases the body will have sufficient glycogen reserves and even food in the in the gust intestinal track to to provide energy saw. Yeah. In most cases, you don't you don't really switch in what we do which is pretty fasting mimicking diet less than longer the last five days. Yes. Then you fully switch to this fat breakdown mall that where there is really no food come in from the outside. And there is no food left in the in the intestine, then we know from humans. Studies actually that there's small short term studies showing periodic fasting. I'll call it periodic fasting since you don't like intermittent. But that's really what we're talking about can actually reduce cholesterol. It can also affect the glucose in the blood, which I think you were also just referring to and all kinds of effects on flam diseases, potentially because of proteins all that. But at the same time, I think indicated this in your last response, we don't know how long these affects last or if they make really for longevity to be greater. Well, I mean, we know in mice that if you do periodic fasting, and this was done a couple of times a month for four days these extend lifespan and reduces cancer and tumors by about forty five percent reduce inflammatory diseases now in our human trial. Did you just referred to? We see lots of benefits particularly in those that have. Problems to begin with. So if somebody has high cholesterol, high blood pressure, high, triglycerides, fasting, glucose, etc, etc. They come down, and they come down more in those that have the highest levels most of the data's with maestro at this point. Right. No, no, this is with this human trial is there was one hundred. Beeson I'm talking overall with longevity and with the decrease of diseases and so forth law mostly mostly indications. We have our from work with mice. Yeah. Most of the studies and the different types of fasting that we described earlier are with mice now with did periodic fast in now, I think there is over fifty thousand people that have done it. Now, we're collecting the reports from the doctors dozens of doctors are falling patients. So I think the periodic fast and he's moving into a different category. You know, I'm biased, of course. Because I I I started all of these. But also I have to say they make also comes from twenty five years of star watching in my own boss, ROY walford here in Los Angeles struggle with the calorie restriction idea, and then learning from all these different practices and then finally coming up with sauntering. There is less invasive and people can do just two or three times a year. And and we think that that's likely to have as we've seen clinically in the surveys now, thousands of patients get a lot of benefits and and at the same time, really minimize side effects. We've seen almost no great three and four side effects. Very few. After fifty thousand over fifty thousand people have done this talking with shelter Longo. He's professor in gerontology biological sciences. US's also director of the USC longevity institute and author of the longevity diet, which we will talk about that's his diet. Jason the Ghada is a clinical fellow in pediatrics at UCSF Benny off children's hospital in San Francisco, and let's find out Dr Nagata about your research and fasting. Oh, thanks very much. So I do population based research, and as you mentioned, my specialty is really an adolescents and young adults. So we used a nationally Representative study that looked at fifteen thousand youth in the United States. They are mostly in their twenties and early thirties who reported fasting or skipping meals with the intention of losing weight, and this is a community sample. This is a nationally Representative people not just patients, and these people were followed for seven years and those young adults who reported fasting or skip. Getting meals with the intention of losing weight actually gained more weight in at seven year follow up than those who did not report fasting. So I think that, you know, one of the challenges with nutrition research, these days is that a lot of the randomized control trials are released short term, and and it's hard to sustain sort of fasting behaviors in the long term. And you know, this is just one study, but we did find that bathrooms actually associated with greater weight gain at seven year follow up, then also connected to eating disorders of young people. The researchers. Yes, so fasting also. Associated with greater risk for eating disorders such as anorexia nervosa or Belean nervosa. And after long periods of fasting, many people may compensate with binge eating or eating large quantity of food in a short period of time, and then they can go and disciples where their fasting and then eating more fasting and then eating more, and eventually they can develop a full blown eating disorder, which has very serious health consequences vastly could be dangerous. I mean, let's put it out there because I think it needs to be seen in the whole picture here. I mean, somebody with cancer shouldn't be fasting. If we're talking about side effects there's dangers involved in pretty much bare set out. Yeah. I think that I like to intervene here if possible I mean, again fasting doesn't mean anything it's like saying eating can be dangerous. I it's really irrelevant. You know, when we use words like that. I it just does damage and nothing else. I think we need to start talking about what are we talking about here? And and just to put it all in in one group is like Putin eating one group and say eating. Hurts people and you say what Dr. Yeah. I mean, I think that the challenge with research on eating or fasting is that people have freedom to do what they would like. And so while one person thinks that their fasting fasting may be defined I giving one meal, but other people may define path thing is skipping for not eating for twenty four forty eight seventy two hours. Look if you skip a meal can affect your blood sugar. Right. I mean it does diabetic. I'm aware that all the time. Yeah. And I think that the message that I would like to get out is that. You know, I especially the more long-term fasting. I don't know about this periodic fasting can be very dangerous, especially for people with type one diabetes. If you have kidney or liver disease. Pregnant women and even children are adolescents growing would not I would not recommend fasting in both population. So I think that there are you know, it can be dangerous in in certain clinical no argument with that. Doctor Longo, would you? I mean. Yeah, obviously it can be dangerous. But it can also be very beneficial. This needs to be for example, cancer patient type one diabetes patient type two diabetes. Patients. We have now many clinical trials suggest on those three diseases in in all cases. We're looking for. We have strong animal data suggest impassively facts. And again has to be standardized has to be tested in clinical trials eventually has to be tested like we're doing in large population long-term, but let's scare people into thinking. They're now this should be now putting the in the category of bad ideas. It's not the debate ideas have to do with poorly executed interventions and fasting is one of them or calories tuition. So there are reasons why people gain weight if they do these yoyo diets, and we know that when people for example, fast an exercise for long periods metabolism source down even compared to the new or based on. On the new weight. Right. So now, you have a problem because now your metabolism so slow and this protective effect to prevent glucose level to become to law. Right. So as we understand this as we combine clinical data epidemiological data basic research now, I think we can turn this fasting which means nothing into something that is actually very beneficial. There's very little doubt about the potential. But absolutely the way it is right now is probably going to end up causing more problems than than benefits. But let me ask you vaulted Longo just about the problem of over eating a non fasting days in why fasting is better than just a regular diet where you cut your calories every day. Well, yeah. So the the guardian the calorie even that depends what we're talking about. But I say calorie restriction. So if you can't your calorie to very low levels for a long period. What happens eventually your metabolism? Not only you adjust based on the the new wait you now your metabolism slows even further. Right. And so that's why it doesn't work and also a puts you in an anorexic like state, and this was what ROY walford may may mantle many years ago. Did it's called calories fiction. It doesn't work. But at the same time if you look at the monkey studies, for example in Colorado. The results and diabetes, cardiovascular disease, cancer, etc. Are extraordinary it'd be completely wiped out diabetes. It reduced cardiovascular disease and cancer by fifty percent..

Professor longo San Francisco United States cancer ROY walford professor USC UCSF Benny clinical fellow director Jason Longo Sacramento Michael Krasny Representative Dr. Yeah Knicks Oakland Mountain View
"gerontology biological sciences" Discussed on FoundMyFitness

FoundMyFitness

01:51 min | 4 years ago

"gerontology biological sciences" Discussed on FoundMyFitness

"When you're done with that get on my email newsletter list you can find that at found my fitness dot com use use the newsletter to announce podcast share interesting studies informative articles and much more and now onto the podcast hello everyone i'm very excited to be sitting here with dr vaulter long ago his professor of gerontology biological sciences at the university of southern california is also director of the longevity institute dr long ago has made huge contributions to the field of aging he is made a significant contributions looking at the effects of fasting and other diets look in the role of human aging life span on bio markers of of health span as well as looking at other metabolic fasting therapies for the treatment of human diseases so vaulter on the podcasts we've talked a lot about time restricted eating from a doctor such an pandas work in how what the effects are eating within a certain timeframe lake at twelve hour at least a twelve hour time window that's in a with a corresponds with a circadian rhythm and how that's really important for a variety of different metabolic factors because our metabolism is on a circadian rhythm but also looking at the effects of having a longer fasting period when arresting so maybe you can tell us what you've done significant amount of research on fasting animals and humans so we are very interested in in asia and really world interventions that extend longevity safeway in investing periodic fasting or better yet fest mimicking diets so these diets that are designed to sarah trick the system and make it thinks it's fasting when you're not fasting so that's where we focus on in the idea really came from a trying to substitute the color restriction.

dr vaulter professor director circadian rhythm asia university of southern califor twelve hour