35 Burst results for "Fayed"
AP News Radio
A moment in time: AP journalists remember Diana's death
"Well wishes in Paris are paying their respects to Princess Diana on the 25th anniversary of her tragic death The flame of liberty stands above the pont del mar tunnel where Diana and her boyfriend Dodi Fayed died in a car accident when the driver lost control of their Mercedes as it was pursued by paparazzi Beside the tunnel American tourist and health worker Naomi Smith remembers the day Diana died I mean it was heartbreaking the day it happened It was a tragic loss for so many She was the people's princess She was down to earth real and it was such a tragedy After diner's death members of the public gathered outside her home to mourn the loss of a young woman who they'd watched grow from a shy teenager into a glamorous princess Charles De Ledesma London
AP News Radio
Diana's last moments: French doctor recalls 'tragic night'
"The first physician on the scene recalls the moment 25 years ago when Princess Diana died in a car crash in Paris Doctor Frederick Mayer was off duty when he drove into the Alma road tunnel in 1997 a few seconds after the high speed crash four people were in the car Two were apparently dead no reaction no breathing and the two others on the right side were living between severe conditions Princess Diana's companion Dodi Fayed and their chauffeur died on the spot I didn't realize that the young lady was the princess not one of the most famous woman in the world And I didn't expect that she died so quickly My a tells the AP he said second thoughts about his treatment of Diana Did I do correctly my job and yes I couldn't have done anything better Those grieving the loss of Diana in Paris still visit a statue near the scene of the crash I'm Ed Donahue
AP News Radio
Princess Diana's 'very special car' sells for more than $750,000 at auction
"A car once owned by Princess Diana sells at auction for just under $764,000 and you may not believe what it is 550,000 pounds on the four escort I've never said that before In the end Silverstone auctions Jonathan humbert sold Princess Diana's 1985 black Ford escort RS turbo S one with just under 25,000 miles on it For just under $764,000 a buyer from a village in Cheshire or England won the auction Silverstone said Princess Diana used a fleet of luxury vehicles for official engagements but preferred to drive the Ford escort for personal errands Next week marks 25 years since Diana along with her boyfriend dodi Al fayed were killed when the limousine they were in crashed
AJ Benza: Fame is a Bitch
Conspiracies Surrounding Princess Diana's Death Are Back in the News
"Back in October 1995, word is Diana asked for a private meeting with her personal legal adviser, Victor mishcon, and apparently she wanted to tell him about something that was on her mind. Something she knew was going to happen. So this guy Michigan takes very good notes of their conversation. During which Diana said that reliable sources and she would name them, but she said that she trusts these reliable sources. That they informed her that a car accident might be stage and apparently she predicted she would have end up dead or be seriously injured in this car crash. Now we go to August of 1997, Diana, along with her partner, dodi Al fayed, and her driver on report, they die after Henri slams their Mercedes into a pillar at 65 miles an hour in that tunnel in Paris. It turned out that Henri Paul was under the influence of alcohol and prescription drugs, but was also trying to Dodge a bunch of crazy paparazzi who were trailing them on motorcycles. Now, before I go any further, I don't know, paparazzi on motorcycles with a camera in one hand that are gonna get that close to a speeding car at 65 mph. I just, I don't know. I wasn't there. I could be wrong, but I don't think they get that close. They got long lenses on those goddamn things. But then again, they were looking for that shot right through the window where they can get her face real close. So it could be. And those shots are worth hundreds of thousands of dollars if they're sold. And they look just right, but according to people in this docu series, miscon gave the note of his meeting with Diana to the London Metropolitan Police commissioner at the time, sir Paul. And it wasn't until after condon successor's name, John Stevens, when he got the post at that point, the public was made aware of this notes existence because the first guy condon had locked it away in a safe. Why he did that? You should ask yourself, why? Why are you trying to hide something like that? It took the next guy to bring that out of the safe. It doesn't sit right with me.
Typology
"fayed" Discussed on Typology
"And the sad thing is that it to be labeled with this condition prevents you from doing your work and moving through that, growing through that, you alluded to that a minute ago, Sarah. But if it's too disruptive, if you can't go to the office, if you can't see your life. Well, then you might need a course of some kind of, we call it anxiolytics. So some kind of anxiety medication, which with which you have been incredibly careful. But you know, sometimes interventions are necessary for people to function normally in the world. Sure. In a way that feels fulfilling. But you just brought up is so important. And I didn't know this, and it also came as a shock, is that the DSM can't define dysfunction. So supposedly, a behavior thought and emotion and experience becomes a mental disorder when it's dysfunctional. But we have no measure of dysfunction. Wow. So we took enneagram types, you know, a twos anxiety disorder is going to be totally different than an 8 or something like along those lines. But so not knowing that, again, what started to, you know, it used to be the dysfunction, and this was in the 1990s. Meant that you really couldn't work and you probably couldn't live independently. That was sort of the ballpark that they were working in. And now, and I often hear this, it interferes with my quality of life. Well, my cat interferes with my quality of life. This is very needy. And I'm a 5. And it's just like, I don't know which type you would be. But you know, so quality of life, I mean, to be honest, being human, all the emotions that are part of that interferes with quality of life. If you look at it that way. So that's another big problem. And then you also raised a great point, which is that most of the time when you receive a diagnosis and certainly all the time, I would, well, most of the time from primary care physicians or GPs is that personality is not taken into account. And neither is context. So what troubles me is you've got kids growing up, you know, children of color, growing up in economically deprived areas. And they're being diagnosed with ODD, which is oppositional defiant disorder. I'd be pretty angry if I grew up in that environment, too. Or sad or whatever it might be. And it allows us to really sidestep a lot of injustices in the world, but also even just a person's own life. I mean, what do we consider justifiable grieving? What do we consider justifiable depression? I grieved, and this is in the book, but I agreed for two years..
Typology
"fayed" Discussed on Typology
"And this was the most shocking to me. They're called disease awareness campaigns or market the diagnosis. And what happens is so I'll give you a very specific example. In 2001, a company called GlaxoSmithKline had developed a drug called paxil. It was an antidepressant and prozac was the drug. It had stolen all of those thunder. They had no market, and they had to come up with another diagnosis for paxil to treat. So they could create another consumer market. And they flipped through the pages of the DSM and they found this very obscure diagnosis called generalized anxiety disorder that affected 1% of the population. It's now the most common diagnosis, okay? And it's upwards of 11, maybe 17%, depending on what statistics you look at. But they ended up getting approval from the FDA for paxil to treat it. So it's also an anti anxiety. And what they did, which is both sinister and brilliant is they didn't market paxil. They marketed generalized anxiety disorder. And what they did is they create fake patient advocacy groups. They also fund patient advocacy groups and those advocacy groups then popularized the diagnosis. And they pay doctors to say, all these people have this diagnosis, but they don't know it. And so that is just a couple of the ways that pharma is involved. And the only reason why I'm not anti medication besides the fact that I'm on it and probably will be for the remainder of my life is that since we know so little about diagnoses and what to do and how to help people with their mental and emotional suffering. I feel like if it's enneagram work or it's meditation or it's walking or it's a pharmaceutical drug, whatever helps you. Like we kind of have to just use all our resources right now is how I feel. You know, and you mentioned this in the book and I'll just moment of transparency. I have been on the same medication for 30 years. And it's saved my life. It really saved my life. Now, I will tell you a story. I literally did my own, I was going nowhere with doctors. And I was really suffering for a couple of years. And it was sort of a mixed state of anxiety and depression. So I was having I was depressed, but having anxiety attacks at the same time. You know, it's called a mixed state. And I went to a doctor, I was talking to a friend who described the exact same experience, right? And told me what the sheep and diagnosed with. I went to my doctor and he went, oh, I was just about to suggest that that was your problem. So I was like, okay, I'm done with you, because you're just stealing my thunder. I just told you the problem, right? And so then I went to see another doctor, and he said, okay, well, we're going to try you on a couple of medications. They didn't work. Finally, he tried the last medication. And it had a stunningly positive effect. Now this medication is used primarily for one quote unquote diagnosis, okay? And it completely I got to say it healed me. It's like it healed me. And so what he did is he essentially backed into a diagnosis, right? He said, okay, this drug worked. Therefore, here's the condition probably, but we don't know. You're not in your head, Sarah, what do you think? That's also the thing that happens, especially often with GPs..
Psychologists Off The Clock
"fayed" Discussed on Psychologists Off The Clock
"Dot com and get a discount code.
The HeFluence Podcast
"fayed" Discussed on The HeFluence Podcast
"Okay no no. No no no good reason. The reason i asked is. Because i think it's you know it's it's We hear people talk about it. But i don't think we ever really hear people express what that means to them like we we say. Hey i want to inspire women. Okay what does that look like like. What does that look like your their cheerleader. Or you're pushing them or you're pulling them or are you leading them and i think I think that's that's super important so last question. I told ashley. I used to have like all these questions that i asked and and then i decided not to do that anymore. Decided to let the holy spirit kind of lead us and guide us and direct us. So when you think about identity about the word identity because we kinda hinted around this a little bit when we first. Before we i got on we were praying and talking about it. Because i think. I'm gonna give you what i think is is happening in our society. Today is my friend. Todd white is a pastor in in in texas and my friend. Theo kalaiana says now ahead of lifestyle christianity ministries. If you don't know todd why you should understand anybody. That doesn't know him. You need to know him He has brands lifestyle christianity He has a video on youtube. That's talks about our identity. If you go to youtube and you type in todd why identity and you watch it. You'll probably know you a little bit more about your identity from god's perspective but i was like to hear other people's but i think for me what i see Is a lot of you. Know one of my favorite books that i always give to My my men client my mail clients and then in one for my female clients. I give them a book women. I gave a book called captivating. Bhai stacey eldridge which is in colorado not too far from where you are and then her husband. John eldredge who i think is one of the most incredible humans that walks face that worth A book called wild at heart And it talks about you know what it means to be a man what. It means to be a poser. It means to you know. Have limiting beliefs in the stuff that Remain that read. It says i can never put it down. I like read it really super fast and never put it down. And so when i think about and i see the identity that we have in our country now and how. We've leaned more towards the immoral side than we have the moral side There's a lot of corruption I mean i'm not going to go down the monkey trae or the rabbit trail of politics. But i mean we can see it like when i when i go to my gas station and last year averaged paying about one hundred and eighty eight dollars for gas and now i'm paying who knows almost three dollars for gas right. So that's why. I say it's super important that we kind of understand that that. So what do you think about when you think about identity. So i did just by my husband that bugging. We're talking about wild at heart. He hasn't started it yet. They told hoping he's reading chased the lion. Which is like one of my favorite bugs. So he's finishing that and then he's going to jump into wild at heart but yeah so for identity. I think that just kind of going with the women thing we need to step into our light..
The HeFluence Podcast
"fayed" Discussed on The HeFluence Podcast
"What does that look like. And how important is that to you. Moving forward in your journey in your business and things that you wanna do that story because we have a long right over here in their letters in it says the world needs. You were made to be. And i look at it every single day and remind myself that god has so many blessings for me. I just need to reach out. Not be afraid to go for them in the he made me with a purpose. So for me. I think is zone in on women not on purpose but i i just feel like i called women because i remember what it felt like to felt feel so broken. Feel like this probably makes me sound really bad. But this is how i felt. My husband was off doing all these big things and i was just a housewife and i love being among more than anything in this entire world. I can see why like love those babies for me. It's not what i was born to do. As far as only being a mom you know an only being a wife. And so i kind of we went through phase. Where like. I blamed my husband for my lack of having purpose because he was gone all the time you know in so when i realized that i was being a whiny little girl the all. You're i can't do anything very much playing the victim card. And i had to get up and show up and do for myself and i really realized like man. I'm a warrior. Done a lie and so i i really speak to women because i i know that feeling so many of us have that mom guilt you know i used to always be someone that is Like going to the girls school. And i still love picking them up and stuff but i was like constantly being a volunteer their at their school at their gym and all of the time and i was like i hate this. What am i doing that you know you. You feel like that's what you were supposed to do. you know. My husband was off fighting for our country. I'm supposed to be at home taking care of these babies doing all the school stuff even though i was hating every second of it not the taking care of the babies but going to the school. In now i've realized i can say notre those thanks because that's not my realm of expertise in by me saying yes. I was taking that opportunity from somebody that really wanted. Anyway you know so for me. I just wanna help women's world and it's okay to have those feelings of like i want more like that's okay because i think for me. I felt guilty for a long time. Saying i wanted more because i have three healthy children a beautiful home in a husband that i love and he's my best friend in wanting more felt very selfish so i want to speak to women and like it's not selfish because those things are wanting four were giving to you by king by our god in. There's a purpose for four that a mission that you're supposed to be living on so i hope i hope that answered it..
The HeFluence Podcast
"fayed" Discussed on The HeFluence Podcast
"I'm risky his reputation. And so i'm just trying to yet just know that he'll get us to where we need to go. One of my favorite sayings is. Because i used to be very indecisive now make decisions very very quickly. It's pretty impressive Because i tell myself that god will. God will bless the good decisions in god will redeem the bad decisions. And so either way. I'm gonna be just fine. Wow that's awesome to hear that Explain this talk to me. A little bit about this so just you kind of know I originally started the he phones. Podcast for men. If you look at my logo it says he fluence right but if you look and you can see the shield of faith right then you can see. The arrow pointing up was for me. I thought it was he. Being god influences me to help i only thought it was men and then god and my wife and all these other women's said well what about us you know and i think as a man of god. It was at the beginning. What was if people don't know my store. My wife and our apart for about four for about two years renewed our vows been together now twelve years. Total and I think it was a protection thing. I think i wanted to let my wife know that there wasn't that was never happening again. That it was and now we all have friends curve girlfriends or my friends. And you know it's it's a there still boundaries there still boundaries. And sometimes i have to. You know i tell my friends i wanna be. I wanna be held accountable. I think One of my one of my new clients today. I just i just got a new high paying clients today that Started a jewelry business back. She had her stuff in over three hundred boutiques and now. It's down to about one hundred because jewelries changed and stuff and so I said what's your number one issue that you're struggling with in life she said boundaries and i was like wow..
The HeFluence Podcast
"fayed" Discussed on The HeFluence Podcast
"She asked him questions gave him every opportunity she asked him about integrity and humility and peace. And all these things right and she walked over he was finished. She walked over to her teams. She said you guys can leave now. She looked up at her lawyer. Said went like like this and walked over to. The guy shook his hand and said thanks but no thanks. You should probably be nicer to waitresses out the door right. So yeah okay. So you've talked about this little bit. Let's talk about this. So you just said for those of you. Listening k She said that she is now. Her husband's getting ready to retire. So now they're just going to go next level business. you know. it's good because your husband's can be husband can be your business partner which is even better so tell me about you. Said you're a little fearful. You're like a little scared about it so tell me about what this next. Season's gonna look like what you said. You wanna stink three to five steps ahead. What does that look like. So maybe somebody's lessening. Like maybe me the same And you know you're hiring. I just i was you now. We're talking about what we were praying before we started you know have hired some people I need to learn sales. But i hate sales of just i do you know john. Maxwell told me one time he said look It's okay to admit that you're not great at something he said but don't focus on it. Focus on what. You're good and i'm good at helping. People live longer healthier life physically on the cellular level. I'm good at helping. People have better vision in their marriage and in their relationships. And how they use that to overcome their fears about things that they're going into those are my superpowers so talk about that. Talk about your what you see the future like for somebody who's where you are you've done you've had success but now you're like okay. I'm going to go bigger. What's that gonna look like. So yeah he decided we. We went back and forth all last year about him resigning because they were offering him the world you know. He's a good soldier in so It's a air force. Now he's special forces army army okay. Yeah so So we went back and forth a lot that i really felt like god kept telling us like get out like you guys got this. Just you know it's time for you. It's time for us.
The HeFluence Podcast
"fayed" Discussed on The HeFluence Podcast
"I said this to my wife about three weeks ago. We celebrated our one year anniversary of living here. And i said so. Do you like it here. And she said no said. I love it here and so when you talked about courage. That's what i thought about. You know what. I wanna do not to get off. But i'm trying to convince my husband. Because gets out of the military in april. When is set like i'm terrified but excited but we've always had that study income so we're going we're doing our thing and going all in on my business and so we're scared but i'm trying to convince them that we need to buy an rv and travel for a year. Oh no no. It's my wife listening right now where she wants to. Its listening when she listens to this tomorrow because she was listened to like like. I'm putting a bunch into the queue. So that i have some for the rest of that And it's. It's the worst thing for her to hear that you're like the third person female that the i've interviewed this month. That said that and now she's going to want to do that so our lease is going to be up in august. If you make. I'm gonna come back after you if you make me have to fly now just kidding. I'm just kidding but i think you should. I think you should may. We also what does have a big travel around the country party. And we'll just we'll teach people how to make all your stuff in different cities really is events and then make nutrition on same time. My goal is is speaking. i love being on stage. You know and and i would love to have my conference be like traveling conference. Because i'm putting on my first of mine not me just being a speaker but made putting one on june and so like if that can be traveling conference. This could work brian. We could and we all by yourself. Yeah i have marcus black speaking. I know you know marcus and alexander. Then i have a couple of other women and stuff so yeah. I'm kind of crazy. Marcus marcus on my podcast. Couple of weeks But back to courage row quick so people always ask me like how you do it. Here's my trick..
The HeFluence Podcast
"fayed" Discussed on The HeFluence Podcast
"In the greatest of all of this is every one of them started off very nervous and very scared and fearful to do live sales to put their product out there that you just you see them grow and really step into their light when they share their story. They all have these amazing stories behind them. We're just continuously helping women you know i always say were. It's collaboration over competition for us. And so we have thirty boutiques sharing their stories helping other women to step out share their stories again applications every day. It just blows my mind that started. I started really all of this. Because i hit negative fifty four dollars and i felt like god was telling me to go for it. You know and he had such a plan. I i told him no because i didn't think his plan was to give me here. I thought his plan was keeping production. But it wasn't in so yet here. We are awesome a so awesome. Because when i think about what you said. You said collaboration over competition and and and i kind of think about how you know I when i look at the thought process of how you know social media is and how people are frightened of it but yet then you have somebody like yourself. That just steps in to The area of something that. Maybe you're not real comfortable with. Can you talk about that like what that meant to you from like. Maybe i need to get a job. Maybe you know. What are we gonna do right to taking your idea and putting it into action. Even when you're like. Well how am i gonna do this right. And what that looked like just from your standpoint of saying okay. god. I'm gonna do this. And the fee because a lot of times people get fearful maybe can chat about that a little bit about what's going through and what those most well first let me say. Whenever i first started teaching people how to make tillerson. I got a lot of. Hey because people were like..
The HeFluence Podcast
"fayed" Discussed on The HeFluence Podcast
"Komo always ask me like how do you do it. Here's my trick. I wrote down my vision. I was very very very clear. I wrote it down and for me. My vision means three to five years from now. Where i wanna be in three to five years and so every opportunity that came up even if i was terrified because remember i'm a warrior and i'm very fearful person when even scared i said were. Were you notice. She was no longer those of you listening. She's fully free and set sees delivered and set free from all of that. If the opportunity align with vision. I said yes. I can give myself time to doubt myself or to. Let's feared.
Bulletproof Radio
"fayed" Discussed on Bulletproof Radio
"Will you take me down to the thrift shop. So i can buy code. And she said well. Are you sure you wanna do that. I mean some kids just wear a lot of shirts for the rest of the year outward michigan car with him and drives him down. The thrift story buys this old coat. Okay himself and in they're riding home and he now showing everybody this coat and is pretty tattered looking and by the way they just they happen to be a family that has some money you know and so people are like a lab. You're having problems with your business. Things like that and and mom said that coat. That will worn out coat that he bought for three dollars gift to him. Then all of the expensive things we him for holidays and so the point here Friends is that you know. We often talk about adversity as being like a really hard thing which it is okay. But there's a flip side of it. How does it feel when you see yourself working through it and you get to the other side. We steal that from people. Don't we we steal the struggle and then as a result we also steal the tremendous sense of confidence and joy that they can have knowing. Hey i got. I got what it takes. I can live this life. I can be honorable and in solve the problems i face. That's resiliency for you. What a what. A great story. And what a great lesson that is for parents and for kids. One of the things that i've found is my kids. Enter their preteen and teen years. I in its well-documented. It kids listened less and less to you and more and more to their peers and some of their peers have been taught to be victims and as soon as something bad happens when they're entitled to a whole bunch of stuff You know the whole victim culture And i would just say high anxiety. High fear peers as a parent. Would you do when your kids start hanging out with a bunch of who don't have any resilience and start picking that style. Well we're working through that right with this is this is really personally great. Dis- discussion so first of all the basic goal is for them to work it out not for us to work it out. We're going to facilitate them working at it out rather than us working it out see because if we work it out. Is it really part of there being no in so that. That's one basic principle. That i that i have to say is is very important. And so there's a lot of times where they'll be all this drama you know associated with hanging out with the kids and then our kids will come home or after they visit with a kid on the on instagram. Or whatever they are having trauma moment the hysteria and that and i think it's very important for us to set a limit with them. That sounds something like this. You know you're you're more than welcome to hang out with me and your mall right here in this room. As long as we're being treated with great respect and we're not having to hear her about negative things. So i sure hope you can stay because we love the this is this is now dramas though drama zone for kids is really cool. I'm like go garlic zone and we have to come across kind of like that because sometimes okay. Here's the deal. I'll admit it my mirror. Neurons are two active sometime. So the kid gets all this drama hysteria. And then i get hysterical about their hysteria. Why why do you want out with kids like that. Oh my goodness you know just modeling. What i don't want so i want to be real matter of fact but loving. Hey i hang out with kid. I do extra things for kids win. I know it's going to be pleasant for me. And it's just not pleasant when i just keep hearing this and that about so and so on this about that and all of the anxiety and worry just not fun for me. So that's part of the message in in a big part of love logic. Is this take really great. Care of yourself in loving ways. I mean when i was a kid i love those movies. They were the old westerns. And some guys horse didn't make or whatever stuck in arizona. Desert crawling along lauder water. You know and and that's like many of our kids now in a desert crawling begging for somebody to give them the leadership that that life sustaining water that they need in order to be successful and i don't know how to give somebody life sustaining water. If my bucket is totally empty the self care and modeling self care and you know. What do we want our kids to be able to kind of learn how to distance themselves from unhealthy peers. Of course we do. Do we want them to know how to take care of themselves around unhealthy peers. Absolutely and how. Well does it work if we're doormat for teaching them to be one. Yep yeah in my son mark Now he's twenty four and when he was little we were. We're constantly practicing we call them. Enforceable statements love and logic does and essentially where we describe what orbited rather than. Tell the kid what to do You feel free to keep the toys that you pick up. A dinner served until such and such a time. And i allow teenagers. Who drive my car. When i don't have to worry about when they get home or were they are. Oh listen when your voices calm like mine things like that and and so one of the things. One of the rules we had is. Oh you get to play with us in hang out with us when you're being sweet to us okay. Well he had a friend over hello played in his four in there in his bedroom. And i sneak around the corner. Because i just love to watch a little kids play you know. And they don't know in adults watching time little matchbox cars on the floor before long. The the friend is taken my son's matchbox cars and smashing them against the baseboard. And here's a little mark lamar. He's got a baseball cap on. He takes it off. He puts all the matchbox cars in his baseball cap. He puts it back on his head. Turns to this little kid and he says i play with kids who are nice to my stuff just walked out of the room pat. You learn that by how say it over and over again.
Bulletproof Radio
"fayed" Discussed on Bulletproof Radio
"From us where we're compassionate but we model strength. And can i tell you story about that. These and by the way. We're not on my outline. Are you okay with that doesn't outline. Jeez well i felt obligated. Okay because you know you're a guy and it's a conversation there's only a few hundred thousand people listening no pressure i loved that i'm going off outline okay and this is the true story. See i i grew up in a in a ranching community and ranching communities all the dogs were aborted collies. Blue healers dogs ran after things. They chased everything they heard. Everything including cars and my dad was of the variety that believe kids needed character-building experiences. Now what let's character building. Experience is doing something hard that you don't want to do but it's good and then afterwards you say to yourself i'm strong i'm capable anna. Did something good so lead. Engineer all these character-building experiences for me one of which was playing my baritone. At all the different places like elks lodges in the small towns and and The rotary clubs in all those. Vfw's so i go and play those little recitals and well got my baritone in the car. And there's buster now busters run an after a saab sobs coming down the road and buster knows that anything that looks as strange as a saab has got to be evil so he tears off after this thing he's going to hurt backward belongs and he gets hit by this car grad from and he manages stumble himself up the driveway. And i still remember neil over him and pet him and my dad ran out and buster died right there. It was a horrible thing in my dad. Loved that dog to a love me and my dad cry just a little bit. This is kind of a silent and he said son. I'm so sorry that happened..
X96
"fayed" Discussed on X96
"Well, it's the battle to be the richest person in the world. Continues. Now there's a story here who says that says that? This Frenchman. Uh, Bernard. Uh, you know, Is Arnaud is the richest person in the world. But then it says, Hope, Hold the hold the phone. A since since the story was written, Jeff Basis is now pushed himself back into the number one spot. But this story was just written yesterday could be different today. I guess French fashion tycoon Bernard Arnault is the world's richest person as of Monday morning. With an estimated net worth of $186.3 billion, putting him 300 million ahead of Jeff Day. Zoe's who was worth 186 billion and then ill on mosque follows with 147.3 billion Arno's fortune jumped From 76 billion in just March of 2020 to 186.3 billion on Monday. A massive rise over 110 billion in the past 14 months thanks to Pandemic defying performance by his luxury group LVMH Louisville home Muay My weight like Moet Shandong Champagne and Hennessy, the fine cognac. Now who's he married to? Is he married? No, No, I was wrong. So, so Salma Hayek husband. His name is very similar to his name, and he also owns luxury brands. Okay. I thought it was him. He's very wealthy, but Well, it's obviously but apparently, Jeff Bezos has just managed to pop back into The top spot, and there's a word. Now that Basis is buying buying Hollywood essentially buying Hollywood. Yes, Frank Get me Hollywood on the phone. He's he's He's pretty much gonna loan Hollywood. Amazon is going to buy. Apparently thean MGM studios. Do they get the lion to? Yeah, comes with it. Yeah, that Jeff. That's the main reason they wanted to Abi. MGM because Jeff Wanted the lion as a pet. The negotiations went like this. It was, but I really want the line. Can you make it worth my while he goes Well, I'll tell you what we're gonna have to charge you. An extraordinary amount of money for the lion, however, will throw in James Bond for free, but, you know, none of that can compare to really the wealth. Masked by Larry Fine, one of the three Stooges. Apparently, he did quite well for himself because His house has been for sale. And dead to me. Writer lives. Feldman and her wife, singer songwriter Rachel Canto has dropped $4.75 million. By the 1925, Spanish Mediterranean. Mansion once owned by Larry Fine. Of you know, the three Stooges, Larry Curly Moe. Oh, yeah, I got wallpaper for that was a bitch. Oh, come on, Bo, let him a load. Larry, fine, Known for his wild, yet balding head of hair lived in this stucco lost, fearless California at the height of his career. From about 1941 to 59 with his wife is my wife, Mabel and their their two Children, is it Johnny? This is Phyllis before buying their stucco. Ella home finds lived in this They lived in hotels. Before they bought the home due to his wife. His wife's dislike of housekeeping. Wow, Come on, you can hire a house. Contrary to listen, Listen, Curly will come in and do some cleaning for us. Not since the stroke. Columbia Pictures ended the Three Stooges movies in 1957. Nearly forcing find into bankruptcy, But he so he decided to sell the home on cut his losses. So this hasn't been Larry's home for quite some time. No, but it is still referred to as As Larry. It's the fine mansion that's Italian bobble. Bo made you head of bounce off the top of it better. That's right. Let's see coronavirus in the United States, Young Americans are lagging behind. With covert 19 vaccines, and experts are pressing for the vaccination of young people. I think Carrie saw of news flash this morning which I haven't seen. This is, um Now. Previously before today, Fizer was the only vaccine that was available or recommended for kids. 12 to 16. Now a now apparently, Moderna has said there's has also been, um Approved for vaccinating people, 12 years old and older, but experts say that Young Americans are facing, Um They may not face High risk forgetting the covert vaccine or serious symptoms, but they still have to contend with long term symptoms. If they get it. Vaccines have been praised as the key to getting the pandemic under control and strides have been made in vaccinating the adult population. And at least 25 States plus Washington, D. C. They have now fully vaccinated at least half of their adult residents, But many experts have identified young Americans. As a critical age group for inoculation success. And actually, Utah's doing a really good job, but getting kids 12 to 15 vaccine er. There's a story that I think is irresponsible today about that, though. Let me find that It's a story about somebody here in Utah who's saying Let me funny? That's right here. Coronavirus among young people in Utah. Where is it? Is heart inflammation, a side effect of covert 19 vaccine fourteen's okay. I don't think you should read this. Well, that's what I said. I wasn't going to but you but you know, you brought it up as Utah's doing very well with the vaccinations for Teens, and this is a story that's trying to Just scared. It's click Fayed. Yeah, it's in the desert at news. And it says that with recent reports that inflammation of the heart muscle may be a side effect for covert 19 vaccines in some adolescents and young adults around the country. Being reviewed by the Centers for Disease Control. It's not a thing so so there have. So there's that report that website We've told you about where people can self report Um, reactions to vaccines on and anybody can post on it. Now there's been an, uh think they said 80 cases. Out of the thousands and thousands of dollars Self reported case 80 self reported cases where they were they have reported myocarditis, which is like an inflammation of the heart now. That could be just that population of kids. There are 80 kids out of how many thousands that that report having that just vaccine or Novaks. It doesn't necessarily have to be related to that. But them reporting it like this is irresponsible, and the CDC actually takes that website that we've said while everybody can come post on it. And they actually look at that and go well. Okay. Well, maybe we need to look into this. But that's as far as it has gone and see. I hate this. This is the headline in the desert, right news exactly His heart inflammation of side effect of covert 19 vaccine for adolescents. Ou Holly Doctor says it's still unclear. Yeah. Meaning? Meaning it's not a thing, but like on this story, meaning this. In this population of this age kids they're studying. What is the normal rate of mild curd itis that's reported in this age group during this time period. Has it gone up? Hasn't stayed the same. They haven't even looked at it yet. It's just a couple of anecdotes that get people all worked up. There's a good story for you. Theo s O Land. And Copeland. He's one of five Utah man charged with crimes connected to the insurrection at the United States Capitol. He said he wanted to talk to members of Congress on January 6th about police brutality and the presidential election..
AJ Benza: Fame is a Bitch
The Crazy Lives of Fay Wray and Robert Riskin
"Fay ray, and the screenwriter Robert riskin, they were an early Hollywood power couple. They each had a very lasting legacy in that town this town. Ray fay ray more people know she's more easily, you know, in definable. She she's the most famous scream queen of them all if you want to get technical. And Robert riskin probably considered the father of the romantic comedy. So they were quite a couple. I mean, men loved fay ray before she was with risking. She was married to a guy named John monk Saunders who was a Rhodes scholar who wrote the story for the first best picture Oscar winner wings, he ended up taking all of her fucking money and kidnapping their daughter. Jesus, later fay ray has a love affair with the playwright Clifford O debts. He's no slouch. And then she starred on stage opposite Archibald leech, and he fell head over heels in love with her, and this was before he changed his name to Cary Grant. Gary Cooper was hot and bought all the Fay Wray. They were in a few films together. But Robert risking a little less recognizable, but like I said, he penned great stuff. He wrote the Frank Capra movies meet John Doe, mister deeds goes to town and it happened one night with Claudette Colbert and Clark Gable. He actually invented the term doodle for mister deeds. Actually, when Adam Sandler remade mister deeds, he kept enough of the original script to give Robert riskin a screen credit. It's pretty cool. But brisket was no slouch himself. He had a lot of pussy after him. Loretta Young Carol Lombard, who Clark Gable went bananas for and when he died, still wanted to be buried next to her, even though they hadn't been together for years and Clark cable had remarried after her. Somebody wild stories when it comes to Hollywood and love lives and who dies and lives next to someone so and eternity at this funeral. I mean, at this graveyard it's insane.
Data Engineering Podcast
Managing The DoorDash Data Platform
"I'm interviewing said here. Taunts about how. The team at doordash designed their data platform. So can you start by introducing yourself. Give having meet tobias. I'm a big fan of your data engineering podcasts. As mentioned earlier. I definitely find it a good source to include mike knowledge. This a lot of good interviews. A lot of good information that can be had from there a duly the engineering organization that we call data platform at ash consists of a few disciplines such as real time streaming platform machine learning platform experimentation platform it a warehouse etc and vina dodi fayed about a year and a half and came from over there for about four years doing something similar managing the data of the marketplace organization at river. So glad to be here looking forward to shut definitely. Do you remember how you first got involved in. The area of data management date as ls fascinated me. When i was a kid rock my first access to computer the first thing i did on. Ms dot crown to type into plus three and hit enter and was hoping that it comes up for the right answer. Percussion it said. Bad commander filename and i was like what anyway. That joke is said to me. Computers were always like number crunching machines and data crunching machines. And of course your rent of internet. Now it's a messaging machine and together with the data crunching capabilities and messaging capabilities. At think is what has made the martin technically possible. As far as my professional engagement goes for the most part of my career. I was a generalist back in engineering. Started my junior netscape back in the days. My first introduction to specically about data and data management was at net flicks reused a joke aren't net flicks that it really is a log event processing company which just happens to be in this teeming movie business to make money and really the volume of data that we had at netflix's what got me really interested in the crunching area. That's where my journey began. It just took it forward at uber who had the passion continued and sheremet that door dash continuing search gonna passionate all the now. Seventy an interesting career are going from netscape to door dash with many stops in between and so you mentioned a little bit about what you do at doordash where you head up the data platform team. Can you give a bit more of a flavor about seven. The responsibilities that fall on your plate and some of the ways that data is used to power. The business adore dash eileen the data plaque from engineering organization. Which for as the internal customers are date. The endless data scientists machine learning engineers. The operations folks are the folks that manage the business on the ground so those are my customers. The goal for the team is obviously to station. The best possible big data stack if you wanna use a buzzword that enables all of the computing power that we need to gain insights entered the marketplace as far as where data is used at nash. A little bit of outdoor show. I'm pretty sure people have heard of the company but a little bit of a primer on doordarshan. That explains why we use. Data jordache is really a multisided marketplace. There's the merchants which could be restaurants are stored owners. That are the dashers who essentially are the folks that drive or or right and and deliver the items and then there are consumers like you and me to that order food or any other items to the app. i'm so that's the multisided marketplace and a few other areas include convenience and groceries where that are other actors in order as well so anyway. This huge marketplace generates a lot of data and the goal of the organization. The data platform organization is to figure out how to harness the power of this large large data set to optimize the market. This essentially ended up to my business. A few examples could include something like eta. Ats estimated time for. I will when you order some food. We door he obviously wanted to come. And as soon as possible and it's critical for us to be as accurate as possible when we come up with eta while if he under predict what the is going to be then it lead to bad customer and bad user experience or or called the likelihood the customer is going to churn and go competing app for example. So these are the kind of work that really are my responsibility on my teams responsibility work with a lot of data scientists tick endless machine learning and genius together to make this possible because you have so many different actors within the platform that you have to try and understand the behavior of nba to optimize for imagined that the current state of the world with the pandemic has thrown your overall capabilities of being able to work with that data and some of your existing models of out the window and of curious what the overall effect has been in terms of the scale and volatility of the data that you're working with and your ability to be able to use it effectively. It's certainly as although we've had steady growth. I should say for many years now if you look at the chart but the pandemic definitely accelerate the shift in our consumers behavior for the most part. They're embrace the denver. The option wholeheartedly. And there's a lot more growth to be had there as well but you're right in terms of wallet tenacity especially talking. The machine learning martyrised that we had earlier bids machine learning modules that typically built on historical features. Which is how the custom whereas the the prediction were based on historical data. Of course that all change when the pandemic hit and yet to retrain our models pursued than new world that was an interesting exercise in addition to that it's about the volume yet volume is increased. Many folds the wisdom of data. I mean and so that brings in challenges in terms are scaling the services that we have the right to set to address the increasing volume the complexity of the use cases that we have now
The My Future Business™ Show
"fayed" Discussed on The My Future Business™ Show
"It's it's a real credited the work that you're doing tennis about the three games. What's et share. Motivation is a big one so a kind of cheerleader. I'm not you know too much in your face knowing and get back. But i try to stay positive and coach you through it and just keep you motivated and get you to the point where it shifts to a drive motivations only an so far i want. I want to build that drives. She got that passion to keep going. So that's a big one movement it's essential even if it's a little bit every day when you're not like if some walks around the block a nice job or a run here and there like just to stay moving it changes so much like you can just be sitting on a couch depressed seeing on tv. Not know what day's gonna come next traded. Promise you yeah if you get off that couch and even if it's as simple as just twenty minutes walking around your neighborhood the combination of the fresh air sunlight just that movement can change everything. Go for a walk up ever. I promise you you'll help out. And then the last one of the three the music which will forever be intertwined with. I spin class background is. That's my favorite part of teaching. Those classes is that i get to create a custom playlists and we ride to the rhythm. So when you connect to fund music that you can relate to whether it's from today's current music. I go back to like the fifties people that makes a difference and so i take that same kind of mindset into my training and when people start up with me i say give me five or so whether favorite bands. Jonah's whatever music they like. That's all i need and you can give me new ones imatra. Whatever it's fluid a changes. But just gimme something to start with and i will build platelets playing in the back on the whole time and that helps keep you motivated..
The My Future Business™ Show
"fayed" Discussed on The My Future Business™ Show
"I get up pretty early and i try to get my workout in first thing because in the rest of the day can just be a mix of different schedules. Each day depending clients. I have And as a matter of taking care of the dogs and then my day of work starts going. And if i don't have a client right away that i work on programming and other business plans and then i want gear up and start getting clients. You're my virtual sessions. I do for some clients have a distance. You're then it's just you know kind of nonstop until bedtime few breaks here and there. But that's pretty much my day. So i make sure to get myself that i need to care for my health and fitness done early and the motivation really comes from my clients and you know my friends. Having my stink class is doing. Because you know. I know these people are hustling and they're working hard so i gotta show up even on the days where it's a struggle and we do voice where as long as you're human you to fate heartbeat susceptible to those days where you just want to pull the covers over your head aren't you. Yes absolutely now. In terms of your your business headed that come about. I know you've talked about it a little bit. I was wondering if you just expand on that compensation and and tell us a bit about when you decided to put some you know physical location in place and what was that whole process. Look for you you know. It was accelerated unfortunately by the pandemic. I was working as a trainer in a big box gym and several clients and was gaining experience there and was just happy to be there and could have been there for years but when the pandemic happened it was everything can't hall. And then when the gyms close i retained some of those clients virtually but most of them just said. I can't do anything right..
The My Future Business™ Show
"fayed" Discussed on The My Future Business™ Show
"Now. You're i love the fact that you focusing on the light hearted stuff because like you say he's just you just don't have to look too far to see the negative in the world. Nothing what you're doing with your businesses absolutely fantastic. We're going to pivot to that. In the moment i wonder do you. What do you think about the upcoming summer olympics. They think it's going to go ahead. Yeah it sounds like it's going to move forward the you know. They're getting really strict on the spectator part and no one from outside. Can no trailers come into the country. And and watch it. And i totally get. That amine shocked that they're allowing spectators at all but he didn't really tight and i think that's smart because these athletes you know just worked so hard so it's nice. They'll get a chance to compete. No do you follow any particular athletes. Do you get your inspiration from anyone in particular. Who do you. who do you follow. Who houston yeah. Few at the moment so many years. That doesn't they talent pin just in general. Yeah because you know it's cool to washington. There's that in that arena. That i can take off hand but i'd say like migration actually comes from purchasing pelleting bikes and the instructors. That are behind that they're kind of just powerhouse olympian level in some ways in what they do and how they inspired people. So that's kind of where i drew from early on as you have a long history with into assortment classes. Don't you tell us a little bit about that. Yeah do that was kind of the start of off all of it. I was running to as part of my cardio. What my workouts. At the time years ago where it makes running and then working with kettlebells for the strength side when we were in a tiny condo and limited on space and went down to the gym and did that and it got the point. Where i'd never really. I liked the kettlebells strength side a lot but the cardio struggling define what i liked and i hated running. I did it just to check the box. And i make the best play. Listen the world and it still was just suffer through all of it and then it started to kind of just take its toll my knees my joints more and i just said you know i don't know that built-in i really wanted to low impact and discovered the sim bike. And at the time. I was pretty. You know always been pretty introverted. And so i went with the at home. Pelton bike route. So i you know. I'm embarrassed and in the comfort of my own home and i just immediately took to. It was just. It just became like a healthy addiction and i loved it and i was bright after ride building up hundred rides two hundred rides and then finally i had friends and family say why. Why don't you think of teaching this like just inside on jam or one of those boutique studios you have a teaching background. You love fitness side of life. Like why don't you try it out. And i just kept pushing it away and then i remember vividly hitting five hundred rides and i was like i never thought i'd hit fifty rides hundred now. Five hundred. I'm just going to take the plunge sign up for the certification and if i'm horrible at it and whatever so i i did it and then i got certified and then you have to audition to get a spot somewhere whether it's out of our studio which is terrifying..
The My Future Business™ Show
"fayed" Discussed on The My Future Business™ Show
"In this big wide world of ours and it's relevant that i mentioned that because on today's show him with wonderful journey faith from a j fitness. Welcome to the show. Thank you thank you for having me. No more we'll just touching momentarily on the pandemic and obviously we're gonna take a deep dive into that chinese bet First of all for everybody who was on the show. This don't know much about journey at the moment by the end of the show you. She's a personal trainer. And we're going to be talking about talking about what it's like to start a business during the pandemic and how to pivot in the fitness industry but before we do any of that journey i'd love to learn a bit more often. Start off by asking a located. I am located in virginia and in fairfax county virginia. It's one of the largest counties in the state and the country. actually what you have is landmark. What people are just about half an hour. Forty five minutes from dc so use of credit pretty close to the capital fantastic. It doesn't get much closer to the center. You're the left to learn a little bit more about you personally in terms of your hobbies and you sports. No you're roy into fitness but did you have any other hobbies outside the fitness industry. I'd say you know love for animals. My husband and i recently adopted our second rescue dogs so we have to rescue dogs now when we got a couple of years ago then one just about a month ago. They they k. What types adults one in particular given skis. Yeah it's what typically with rescues it's really kind of guesstimate what the breed is. There's no way to do one of those little fun doggy. Dna swab test use but so one of them is is the first one we got. More of a terrier chihuahua mix and the second one one we got is more like a terrier chihuahua. Dachshund make tiny and law it'd be quite comical was a loving beautiful tim from indeed..
Houston Public Media Local Newscasts
Houston day laborers suffer wage theft in post-winter Storm Work
"In the wake of the winter freeze day laborers and other immigrant workers are already reporting incidents of wage theft. Is they help houstonians recover. Elizabeth trove all has more on. How many of the storm's second responders are in positions that are easy to exploit houston's fay who st. A worker center has received reports of people going unpaid for their work after making repairs after the winter storm. The group's legal manager jessica. Da's says they're expecting to see more claims she says it's part of a pattern she seen in houston disaster after disaster people new day laborers and the workers put themselves into vulnerable positions to secure job. It's a no question kind of scenario right. You just get in the car. Whoever gets in the car Get the job right. You don't even ask how much you're gonna pay you. You don't even ask about blair who they are. Where they're taking new gives says over the past year. Her organization has received reports of over three hundred thousand dollars of unpaid wages in the area from two hundred workers. I'm elizabeth travel in
News and Perspective with Tom Hutyler
Asian couple assaulted in Chinatown, Seattle PD investigating possibility of hate crime
"Johnson Come on news. We're working to learn more about the 41 year old man arrested for a random attack on a couple of Seattle's Chinatown International District last week. Police still trying to figure out if this was a hate crime. Rico now also and Michael Poppin Barger were hit with some kind of heavy object. Noriko has a fractured nose and broken teeth. Michael needed eight stitches in his head. Coma, spoke to the couple by text about the arrest. Michael told us quote. I'm very happy the police made it happen. I won't feel like someone I pass or around the corner. Everywhere I go. I hope his arrest will help that stress. Fay, those the
Airline Pilot Guy - Aviation Podcast
Indonesia Plane Crash Probe Centers on Engine Control Problems
"Okay. The first item in our news segment is from wall. Street journal dot com indonesia plane crash probe centers on engine control. Problems the dad. The data indicates the data indicates the so-called auto throttle system which automatically adjusts feel flow and thrust to maintain the paths at. My pilots wasn't operating properly on one engine. At some point during the boeing seven. Thirty seven five hundred. Climb away from the nation's capital jakarta on january nine according to some of the people familiar with the matter instead of shutting off the system. They said the flight data recorder indicates pilots tried to get the stuck throttle to function such engine control. Malfunctions can create significant differences in power between engines making a twin engine jet harder to control and it kapit potentially distract pilots from maintaining a safe flight. Okay twin engine aircraft such as the seven thirty seven are designed to fly safely on a single engine. I don't know why they're talking about now. Single engine because we're talking about an auto throttle anyway. I'm sorry i should read the wall street. Journal article twin engine aircraft such as the seven thirty seven are designed to fly safely on single engine and pilots are trained to do that in various situations but large differences in thrust between engines according to pilots and safety experts require swift pilot recognition of the problem. Which would ideally be followed by quick responses and manual commands. Harjo sought meco deputy head of indonesia indonesia's national transportation safety committee confirmed the probe is looking into an auto throttle problem. He said investigators may obtain specific information about the pilots handling of the auto throttle after listening to the cockpit voice recorder which authorities are trying to retrieve from the crash. Site that device. The plane's second black box could shed more light on what pilots were saying on the flight. Deck as they responded to the malfunction Let's see those familiar with the details of the probe. Along with safety experts tracking. It said it was too early to draw definitive conclusions about why two experienced pilots lost control. The jet or what other factors may have contributed to the crash information from the flight. Data recorder is under further analysis while pilot records and maintenance files are being examined. Investigators haven't detailed the primary focus of the probe. Though they they say that both engines were putting out power when the jet hit the water killing all sixty two onboard they also have said the location of debris indicates the plane was intact when it hit the water so it goes on in this article a talk about the flights and information. I think that we've already discussed on the show that so apparently there was on previous flights. There were a couple of write ups individual write ups on different flights About the auto throttle system and if that is indeed what happened. Here i i. Don't it's hard for me to mel again. I i hate to say anything because it's all speculation but if the bottles don't work properly than shot the auto throttles off the airplane flies. Just fine without a throttles. There are a lot of airplanes out there today. Blind without auto throttle system. So i hope they didn't get so distracted or focused on the system. They let the airplane. Get away from them and Crash but they tend to be pointing in that direction. I think yeah. I wish i knew more about the seven. Thirty sevens systems but If if i'm guessing correctly The throttles would move In response to the auto throttle which would generate the correct response in the The fayed echo the macula. Whatever feel control system there is On the and these engines So i'm just a bit bemused as to why particularly when you have got You can see the throttled move in response to what the throttle is doing. You can detect the problem. I would be very surprised. That they if they got uncommanded or throttle movement that they wasn't an essay shaded warning with it a bit surprised that the oldest shuttle didn't attorney itself because normally what all throttle does something unusual it's detected by whatever full system there is in the system mandate will turn itself off So yeah. I think you're probably right jeff I think they may have got Over very interested in trying to solve a problem on weren't paying enough attention to what their plane was doing In this situation. It's very important for the pond flying to concentrate on his job and who was trying to find the issue It just to Do their thing almost independently both get involved in trying to fix. What is effectively is just at part throttle full. As you said is relatively minor pro.
The Bio Report
Using Computational Discovery to Build Better Immunotherapies
"Team. Thanks for joining us dan. We're gonna talk about immunotherapy compuserve and its efforts to pursue novel targets for ahmed cancer types. Perhaps we can been gin with the idea of checkpoint inhibitors what are they. And how do they work. He'd be taurus. Are actually proteins modulating the immune system responds in the context of fay affair. Kasim yuna therapy. It was identified. There is a crosstalk between immune cells and and the cancer. This crosstalk is being done through immune checkpoint and and usually these are inhibiting the immune system response to the to the cancer to the cancer cells and and the drugs the few drugs that are out there that are dressing these same immune checkpoint skin to treat cancer. Patients are actually am inhibiting. The inhibition exerted by immune checkpoint on the cancer cells in diff- therefore allowing the immune system to be stimulated and actually fight the cancer. This has been a a real revolution in cancer. Care but these still have limited efficacy. How how effective are these therapies at treating cancer today as of today about twenty to thirty percent of the patient population of the cancer patients are responsive to these drugs. It is increasing with time. We're more proven are being done with the current in hebrew tours. But i have to say that you know. Cancer is a movie factoria disease and and it's actually a collection of many different diseases and we're not in a situation where one treatment fits all basically declined immune checkpoint a drugs are addressing only few number drug targets and they're still many mechanisms that need to be a still a explored and and identified and drugs need to be developed in order to address the various mechanisms of action by which the kansas are actually avoiding the immune system. And here's actually that were. Competent fits in and see what we do. Discover new drug targets and developer first in class drugs to address. These struck targets copy. Jen has developed a computational based drug discovery platform. What is the platform. And how does it work. So the platform is is basically based on twenty years a fan and know how that was built at computation with being a computational discovery company for many years and then after we established a critical mass of discovery capabilities. We turn to be to. We are today. Pretty discovery and development company in generale with built computer systems tucson algorithms in order to be able to address the challenge of new drug targets discovery. And you biological halfway discovery. Identify new drug targets is a is a is a very complex isn't f. fourteens. Multiday mentioned effort and for that we had to develop a multiple systems. We've built a lot of know-how in the company and we've built a Expertise in what is called multi onyx analysis. We're not limiting our platform to a specific data type or a specific technology. Actually we're very flexible. Tools and systems an algorithms are really designed to address multiple data sources multiple data technologies and. This is because this is multifactorial and complex and filled to work in. An all of these are augmented with human expertise that we have in the company in the last twenty years. How do the targets. You've discovered differ from the targets that today's checkpoint inhibitors go after and it's very good question. Actually it's not very different in terms of you know still it's checkpoint but i think that the nature of checkpoints one as compared to the others those that are known and those that we discovered these are proteins. That are very different from one. Another so yes all of them. At least those are defined as negative customer tour costing military checkpoints. They're all inhibiting the immune system response against the cancer. But they're doing it in different ways and what we discovered is as i said you know the checkpoints are now have been translated to drugs that are in the market. A really only very few. I think about three or sociology for pd one. Pedia want and what we discovered. Is you know you biological pathways debts allowed us to discover new immune. Checkpoint that are still inhibiting the immune system response against the cancer but in a different way a different mechanism and this allows us to be able to develop hopefully no new treatments solutions. That will address those cancer patients the not responsive to the current checkpoint inhibitors check on earth. What are the issues with. Existing immunotherapy is the ability of cancers to develop resistance. Where are you doing to address that issue so this is actually exactly what we're trying to do. Am that in cancer. Immunotherapy is there are two issues right there. Ease the patients that are not responsive in does that with time that are developing what is called acquired resistance. We're we're trying to do in. The company is to try and focus on those biological pathways that we believe would address those patients that are not responsive to the current checkpoint blockade. So they're in different ways with different. Mechanism does cancers data and actually deliver a different solution to the problem. And this will were trying to work on. You know the leading the leading drug that is in development at is now owning phase one studies and we have owning michel data in the clinic but the days actually am supporting designs behind. We discovered so we discovered a completely new biological pathway identified sen typically that it is addressing am in. You am a new mechanism that still this family of immune checkpoint. The preclinical data suggested that it should address
Short Wave
How A 100-Year-Old Treatment Could Help Save Us From Superbugs
"In twenty fifteen. Stephanie strategy and her husband tom paterson. Both scientists were travelling in egypt. They sell the pyramids the nile and then as she tells it in this text talk after dinner one night. Tom became violently ill. He vomited all night long. And i thought oh gee he's just got food poisoning and i pulled out a couple of antibiotic pills that we take with us on our trips and i gave it to them with some water. Nothing happened the next day. Tom kept vomiting. Stephanie called doctor he thought yes food poisoning and set up an iv drip for more antibiotics. But tom only got worse at a local clinic. He was diagnosed with pancreatitis. Inflammation of the pancreas and medevac to a hospital in frankfurt and there. He was diagnosed with something even worse. A superbug a bacteria by the name of oscillator b-actor bowman scary name scarier bacteria it tops. The world health organization's list of most dangerous superbugs bacteria that are very hard to treat often resistant to many antibiotics. Now we'll never really know for sure where time got his superbug infection. But we do know that. It was an egyptian stream. And we know that. By the time he was medevac. Thome to san diego that it was resistant to every antibiotic. Tom was in a coma. His organs were shutting down. He was on three different drugs to keep his heart. Beating and the doctors told me that tom was going to die. But seventy refused to give up. She turned to the scientific community for help. I'm maddie safai today. on shortwave. What stephanie found and how it saved her husband's life. It's a century-old treatment. That could be a new tool in our war against super bucks for months stephanie's husband. Tom would remain hospitalized fighting for his life and losing. Yeah i was just really scared out of my mind. But i knew that if i just sat back and waited then he was going to die and i needed to know that i'd done. Every last thing that i could do that i would leave no stone unturned so i hit the internet and i did with anybody else would do in my shoes. Google it well. Luckily you know there's google for scientists and that's called pubmed and it's this wonderful search engine where you can put in any words and a scientific paper will pop up and you know i punched in words like multi drug resistance and the name of his superbug which is assassinated b-actor mania and popular within an hour. I found a paper that mentioned something called page therapy. So tell me a little bit about fish there. Well fay jr are short for bacteria phages and that's derived from the greek word meaning bacteria eater and they are viruses that have naturally evolved to attack bacteria there's ten million trillion trillion pages on the planet. It's all a matter of finding the ones that will kill the bacteria that you want to get rid of. Okay real quick phase one. oh one i like. Stephanie said bacteria phases the viruses that infect bacteria are everywhere pretty much anywhere you find. Bacteria you'll find a phase we're talking and artika deep-sea ocean vents your. But i swear that'll make sense later. Second facials don't actually eat bacteria in this case the fees injects its own dna into the bacterial cell. Then the virus forces the bacteria to make more and more copies of itself feeling up the cell with viruses eventually the bacteria bus open releasing all those new viruses. Go off and kill other cells. It's ruthless
Vicki McKenna
Wisconsin Supreme Court Hears Arguments In Challenge To Evers' Emergency Powers
"The Wisconsin Supreme Court is hearing oral arguments today in regards to Governor Tony Evers, statewide mask mandate box sixes and delicate area, explains Waukesha County resident Jared Fay. Vic. Filed a petition against the governor's power to issue the statewide mask mandate, according to the lawsuit Favorite argue state law prevents a governor from issuing more than one emergency order for the same pandemic. Governor, Evers declared the state wide mass mandate after he had declared a state of emergency and asked people to stay home. The Supreme Court is looking to answer two questions. Did Governor Evers violated state law when he declared a state of emergency and put those orders in place? And whether the orders are an unconstitutional legislative power used by the executive branch.
Bloomberg Businessweek
An index of small-cap stocks just notched its first record-high close since 2018
"Look at some of the stocks on the move and the sectors of the move on Carol Master along with Bloomberg News process that reporter Sarah Pounds Act, both of us in our Bloomberg Interactive Brokers studio. Let me just do big picture. Definitely risk on trade 473 names in the S and P 500 higher today 31 lower to unchanged And if I take a look at those major industry groups in the S and P 500, there are 11 all of them up. For the day energy at the top of the pack of 3.8%, followed by real estate of about 2.3 bottom of the pack information technology, but still up about 9/10 of a percent Sarah Ponds Act, Man, It wasn't the week. Well, maybe it's starting more like the week. It's ending. More like the week it started. See, that's what kind of weak it's been, and there's been a lot of stuff in the middle, right. We have come full circle. Granted, Today's moves were not as drastic or as large as Monday's, but they were reminiscent of them in the middle of the week. We saw that Monday rotation, Fayed was attacked, Take the lead once again. That was not the case today. At the end of the day, we just heard it. Russell 2000 more than 2.3% today at a record high. This is the first record high for the Russell since 2018. We had not seen it. It really is. It's been got. It's getting close, right and just never breaks it right, exactly exactly have been getting close. But we have not been able to see small caps really breakthrough. While today was the day also a record high for the S and P 500 today, as well as the equal weight version of the S and P, So we're seeing breath come into this market. Well, that's what I was going to say. What's the significance about the small caps in the large caps right to see the Three indexes that you just put it point out there all hit records. So the idea is that sure you can see the SNP it records. You can see the NASDAQ hit records, but they're very, very top heavy. So what that means is that it's really representative of just a few stocks, many of them tech thing, names all year long pulling higher seeing Russell 2000 at record seeing the equal weight version of the S and P. It records What this shows you is that it's not just a couple of stocks pulling you hire. Rather, it is many more and you are seeing more participation, which is seen as a healthy climb. What's the fundamentals behind it? You know, it's a great question. So a lot of hope this week on the optimism over the visor vaccine is truly It's unbelievable. When you see these stark comparisons between the Fizer vaccine news, then you see Record covert 19 cases. You see restrictions coming in what the reality is and what investors are saying is that the vaccine news helps you look beyond all of this. That helps you realize that there will be an end. At some point. I hear it all The time. Markets are forward looking mechanism, and that's exactly what they're trying to do what you got visibility right? And even if it's still a few months away, or maybe it's into next year well into next year. At least we have an idea of when this will end versus some of the conversations we had earlier this year when we like We don't know. We just don't know
Ben Ferguson
Man shot, killed at Northwest Dallas gas station
"County. A man was shot by a wolf City police officer last night. Prince and family say Jonathan Pryce, the man shot by the officer was trying to intervene in a domestic violence situation before he was killed at the quick check gas station at 103 Satya Fay Street. The man in the domestic violent scuffle assaulted price. And then when officers arrived, they used a Taser on price before the shooting, the officer involved has been placed on administrative leave. Relatives and friends said Price was a city employee and beloved in the wolf City community. Ah
John Batchelor
Tropical Storm Isaias Forms In Caribbean
"Tropical storm CCS is now forming in the Atlantic. With tropical storm warnings for several Caribbean islands. Now, in effect from meteorologist John Trump Tropical Storm Essa is has formed in the Atlantic Ocean. There are tropical storm warnings throughout the Caribbean. Most of the models are now trending that the storm will move more to the eastern side of Florida and be near Jacksonville, this coming Saturday night. Lisa is broke the record for the earliest ninth Atlantic named storms so far this year. Crystal ball Danielle Eduard Fay Girton. Hannah also set records for being the earliest named Atlantic Storm system for their
WBZ Afternoon News
NEMA urges public to prepare for 2020 Atlantic Hurricane Season
"And tis the season hurricane season that isthe Mima wants you to make sure you're ready for it. The 2020 Atlantic hurricane season is off to a blazing start. And with Fay, the sixth named Storm of the year, having whizz through these parts last week, 2020 is on a record pace. We are going into the peak of hurricane season and we certainly are and exactly where you live could heighten the amount of risk you face for people that are along the coastal area. Flooding is the biggest risk when you look at the winds and heavy rain. Fall even far away from the coast, pretty extensive damage it can happen. Chris Bessie is with the Massachusetts Emergency Management Agency. He suggests we all build an emergency kit of supplies. Everyone sort of emergency supplies would be a little different, but everyone should be sure to pack face coverings in sanitizer. Anything you may need to protect yourself from covert 19 in the event. Your home needs to be
WTOP 24 Hour News
Washington, DC - Tropical Storm Fay causes flooding in Ocean City
"All parts of the East coast, including Ocean City, Maryland, have some cleaning up to dio were soaked by that tropical storm There was flooding reported from Maryland's eastern shore to New York City from Tropical Storm Fay after the storm developed suddenly on Thursday, just off the mid Atlantic coastline. The storm was at its peak yesterday morning and afternoon and maximum sustained winds hit 60 miles per hour. Ralph Sasser lives in Ocean City, he tells w. B A. L T V. He's never seen so much flooding on the north End of town. The water was coming up like underneath of my truck and I thought that it was going to flood my trunk out. It did lead to a lot of flooding in Ocean city, dumping six inches of rain in a short period of time, but no serious damage was
WTOP 24 Hour News
Effects from Tropical Storm Fay causes flooding in Ocean City
"East Coast, including Ocean City, Maryland, are