8 Burst results for "Facet Journal"

"facet journal" Discussed on A Light Read Read

A Light Read Read

13:18 min | 1 year ago

"facet journal" Discussed on A Light Read Read

"And until then this is going to be a problem. there's a seventeen million dollar lawsuit in New York state over the Tappan. Zee Bridge lighting failure. You may have noticed that the lights on it didn't work as advertised and seaport. Lighting is suing. Well everyone else. Involved light style. Automated Systems signify wells back electoral con on tractors because Well the specifications didn't include Booz surge protection when they should have. And that's why a whole bridge doesn't have lighting great stuff. Lighting practice is offering a primer on lighting controls. Now that we're entering a low contract world snap count has announced a digital convention. This is A. They're very on retrofit showcase their positioning it as a alternative to light fair. And I'm saying that more and more Marketing departments are going to work really hard to create digital equivalents. To all the shows. We missed out on this year Be Careful Mr Ted Cruz of the United States Senate is concerned about rare earths. He's urging the Department of Defense and the Department of the Interior to Source rare earths from more reliable places ideally within America. Good luck to him on that The DLC has extended their timelines related to version five of their requirements. New Products have three more months to sign into the sign on to it While existing products were just looking to go from Ford V. Five are have an extra month. Dimming requirements are GonNa sit tight until version five point one at this point the L. R. C. has a assessment on UV lighting in neo natal intensive care wards. And well certainly fine. They're not quite good enough for hospitals just yet is the finding episode. One thirty three of the grip on lighting should be live. This is a quick quick talk with Mark. Leeann talking about the lighting industry and the future weathering this and where it goes from there The is women are on germ seidel. Uv has been scheduled. This is set for May seventh And it will cover a range of topics related to you. E- lighting Are I joists a fire hazard authorities in the UK are concerned that I joyce combined with down. Lights are just too much heat. Keep an eye out for that Signify his refinanced Bunch you debts related to their acquisition of Cooper they are being issued one point two seven billion in eurobonds over the next seven years to cover that inventory onyx has added new safety procedures. This is a driver maker who are very keen to let you know that their employees in China the US and Europe will be safe as they start working again. Flex works illumination has settled a patent suit against O. Kt both parties are dismissing all claims. All counterclaims on a bunch of undisclosed conditions as well as the disclosed condition. That Okay T. will stop selling you one product in the US and Europe and modify another Big Data and smart cities is a topic of discussion at data topics. This is peace devastating into the implications of large scale. Iot Data analytics. Ms IS LOOKING FORWARD TO Q. Two they're saying that they're they're saying that the next half years going to do quite well for them. L. S. G. and TCP have rebranded up sorry L. S. G. and their TCP of an ongoing patent suit that has been remanded for further consideration. Solar Street leading projects are expected to that marketplace is expected to grow by seven billion dollars over the next five years. There's a new platform from quantity that is going to use a lighter for social distancing enforcement misses. Us light beams to tell how far apart we are. Hubble is still going to issue a dividend to their stockholders this quarter in this case. It's all-stock Ordos will receive ninety two cents per share. Lp's is continuing their digital conference series in this case talking about measuring road lighting quality of interest to anyone that's ever had across the street cree has reported revenue losses abysses Q. Three last year so unrelated to current troubles. But they're down about twenty percent compared to q three two thousand eighteen h e Williams has partnered with BIOS. A BIOS is a NASA spinoff research project for Circadian Lighting H e Williams will begin to carry their tech in a whole new product. Line is energy. I hope I'm saying that right. That said NERD G Has Hit he is predicting the future. They're an led conversion for business and they expect things to return to normal for them at least by the end of the year. Philip lay on of the PNN L. His talking about their integrated leading campaign so they've spent five years working on interior lighting awareness. And they're setting new goals for the next five years Professor Joseph G Allen and John D. mccumber are writing about what the hierarchy of building health really means. And this is not just Keeping things clean but keeping the occupants in good spirits and what that means right now A case study on fake neon signs is available to read this as a mix of glass tubing and. Led's that look much more like neon than tape lights or other sort of flexible solutions but still maintain that hath energy use that you get from led Nolte lightings offering. A weapon are in better sleep. Mrs On the Fifth Tomorrow at time of release and they're talking to lighting designers about incorporating light for better sleep We have a theoretical framework for wide band gap. Semiconductors that's been published this is from eighteen in Monte Carlo and it's a new structure for silicon wafers that will make for better eelectronics enlightening across the board. North Dakota wind farms have been fined for lighting violations. This is in Emmons and Logan Counties Fines are stuck with five thousand dollars because well the lights are still on at night and nobody likes that. Apparently the AWA lighting designers are talking about writing for wellness. This is a newsletter and offering videos on Home Office leading you in a bunch of other topics so a tube of San Diego or making P P one of the many leading fat firms that are converting some of their facilities to cutting face shields. Good for them Architecture daily has some tests for lighting in children's spaces that's worth a read a Alan Tula at lex review is reviewing terminable lighting tune. -able down lights so get an idea of what's good and great in tune -able down lights. Sauk city has installed solar store solar and energy storage hybrid lighting systems in their parks. This is in Wisconsin. And apparently switching to a micro grid is just cheaper by half then converting an entire wired system good for them Normal lighting as named erupt age in Idaho. Mrs From one of their former employees. But it's a new agency Northwest lighting will be covering the state Buyer. Beware because Some Ebay scammers are selling disco infection disco as disinfection lamps They're using party great back lights and pretending they're UBCV's now. I don't think any of us are buying disinfection lamps off Ebay but again going back to. Uv is not magic some people are going to exploit that so be better High brightness led market growth. This is from Predictions from premium market insights. They're expecting this whole space to grow by ten percent over the next two years. The Association for Advancement of Sustainability in Heiberg higher education is calling for three Texas universities to go green. They don't have any projects in the offing. And that's upsetting to them. Hazard is location. Led's are going to expand by about ten percent over the next five years. According to Port Lincoln signifies backing default Ri-. They've got new drivers under their certifications for Iot Chris. Hatschi is telling us what the best time switch for. Lighting is good read A. Here's a D I y project for you your own. Uv C. Disinfection Chamber. For your phone or your gloves or your homemade facemask. Whatever you need this is a handy little off the shelf project that you can build too clean that speaking of Dia y projects home talk wants you to know how to make a concrete lamp. Yeah it's brick and then inside there's a room for a light bulb and socket and everything it looks nifty. I don't know when I'd use it but it looks nasty. And the Imperial College of London has combined mushrooms and tobacco to create well a glowing tobacco plan bases Foley Bio Luminescent. And they're saying it's going to be of interest to botanists who will well use this spicing to examine how plants to better examine. How plants grow because it having lighten. They're just makes it easier to look at the cells but also probably for decoration The Marine Parchment tube worm secretes a Goo- that is bio luminescent. Well and they only do this when they're stressed same. Their tube worms This According to a Facet Journal this might be the light source of the future. A California couple would rather ask out of state friends to smuggle bombs than buy new dimmers. This is a editorial from Arizona. And well I try not to. Aditorial is much but I think this person is more interested in dunking on perceived values across state lines than Really discussing whether or not deductible. Led's exist progress. Lighting has released a new catalog. And it's been different in that you can print it at home so she saves on shipping and it's also a coloring book. I don't know what you're doing to kill time. But coloring book seems Nifty City of Dallas is calling for better Turks Sky Protocols and fast because a few hundred thousand songbirds are GonNa fly through the city and It'd would be nice if fewer of them hit windows. Getting into hirings and promotions. Chris Stockton has been named the CEO of Nordion. Sterling lighting hired. Nels Peterson is designed sales and support specialist and Levy Tron. Gabriel misogyny is set to retire. And that's it. That's me This this is it for the week. I'm Scott Walker. This has been the light read brought to you by nailed get associated get more than just the news get some get some connections. Get more out of your life through.

Led US Europe e Williams L. S. G. New York Zee Bridge Mr Ted Cruz Department of Defense Cooper UK United States Senate New Products Ebay Philip Chris Stockton NASA Sauk city Leeann
"facet journal" Discussed on FoundMyFitness

FoundMyFitness

11:31 min | 1 year ago

"facet journal" Discussed on FoundMyFitness

"Hey folks today's episode was originally recorded for the cabin. Roadshow may already be familiar with Kevin thanks to his history. As a notable personality in the technology world his frequent guest appearances on the Tim Ferriss show and the many many podcasts hosted over the years however those of you who we're not familiar with Kevin he comes at a lot of this health and lifestyle stuff as an honest to goodness hardcore any self experimenter. I think this really impart certain certain. Spirit of practicality. An implementation emphasized a little more in this conversation than others. I've had not to mention. He has quite a few highly relevant anecdotes. Vikto he drops into given some of the unique discussion. We had I had no choice but to ask the Great Kevin. If you would let me re post it over here on the foued fitness podcast feed a request which he graciously obliged in this discussion with Kevin. We discuss the unique value phospholipids. Dha has has due to its propensity to be metabolized into a formidable mega three Dha metabolite that utilizes a specialized system of active transport mediated did by a transporter called SD to a which helps get the Dha across the blood brain barrier. This is important because an alternative means of transport report which is passive. Diffusion may become less effective as disease an aging impairs the blood brain barrier with as important as Omega Three. Dha is for the brain finding new and better ways to get it. Transported into the brain may be good news while phospholipid. Dha which is uniquely found in some specialized sources. I like fish row where it makes up to forty percent of the total. Dha content may stack the deck in favor of getting a greater quantity of this actively transported metabolite called Dha Lice. Oh false title calling women also end up with more of this metabolite just through greater intake of marine omega three fatty acids as a whole since at least some of the last lie so foster title colon gets produced even from more conventional forms of. Dha We get like the triglycerides form found in most fish oil oil supplements in addition to this Omega three discussion. which actually makes up a lot of this episode since it is based off of my own published work? We also cover some of my thoughts on Metformin a foreman as a health span strategy. We talk about animal and human research here. Both of which has some interesting twists and turns we talk about Sulfurophane and unique compound richly found in Broccoli sprouts and the somewhat recent evidence that it increases Gouda found in the brain in humans. Glutathione is a potent endogenous antioxidant. Can't we also discuss some of the concern surrounding sulfurophane. As a potential go Trajan we discuss supplementation and more we talk about my thoughts on magnesium. Am L. Three and eight thanks to some of the animal and limited clinical research suggesting it might enhance cognition. We talk about the Sauna a passion Kevin I share and and some of the research. That's come out. Since the last time I talked. Finally we talk about some of the recent updates on the foundmyfitness website particularly the new premium membership for those of you. That enjoyed this conversation. Please make sure to also head over to Kevin's itunes. which you can find googling Kevin Roche Oh he's had many any overlapping guests? We've had over here including doctors David Sinclair and Volterra Longo outside of health span. He also interviews founders entrepreneurs and notable we'll personalities from the investment world which you can also find represented on his recently relaunched podcast called foundation also on I tunes Beak Week. Thanks to Kevin for having me on now away to the episode. Everybody Kevin Rose here. Welcome back to another episode of the Kevin Rose Show happy twenty twenty. It's a brand new year her and so I'm really excited to have doctor Rhonda Patrick on the show. Because what better way and thing to address than health longevity in January. It's surely a topic topic that is on a lot of our minds. I for one. I'm going to try mostly mostly PESCA -Tarian Diet for this first month and get my blood work checked and let's see what it does to some of my numbers. I'm also going to be cutting out drinking for the most part because I have a trip planned to Japan. At the end of the month I will be drinking in Japan will be having Sakai and good Japanese beer but the first few weeks I will not have any any drinks and get blood tests before all of that anyway Doctor Rhonda. Patrick is one of my favorite scientists. She goes in reads. All the published studies around health and longevity and really takes that information out of there that is too technical for the average person understand and then translates it into things that we can incorporate into our everyday lives. This is the best way to get your health health advice. People like doctors are always always four five ten years behind except for Dr Peter Tia but but the average doctor is many years behind what the science is actually telling us to do. So if you want to know the latest and greatest it's best to go to scientists and thankfully do podcast and Rhonda has a fantastic podcast and also a great website called foundmyfitness.com. She has been able to give us that direct link to scientists so she interviews a bunch of great scientists and really help us make better decisions earlier on so for example in this episode. We talk about a Omega threes. And why they're not all created equally and there's various different forms of Omega three. We talk about which ones that she takes. How much she actually takes personally? Lots of great information there because not only is she understanding the science to relate to us but also has published her own science around a mega threes. And she's done a bunch of research in regards to get through impact on dementia and Alzheimer's so great to have her talking about that. We also talk about metformin which is a very hot drug right now hot. I don't know if you can call a drug hot. But it's a very popular drug at least in Silicon Valley for people taking to extend life and some of the potential pitfalls hit falls that it has we also talk about a compound called sulphur fame which is found in Broccoli. She talked about at length on her own. podcast about sulfurophane gene but there is some new data out there that we cover and we also talk about a new brand of sulfur fame that she has imported that she takes so a lot of interesting stuff. There we cover sauna usage. Some new studies have come out there so a lot of really knew things to chat about in. This was a great episode. I really enjoyed it and I know you know that you will too so happy. Twenty twenty cheers to you. I'm really hoping that all of you stay happy and healthy this year introduced some new healthy habits. It's into your life and Hopefully subscribe to all Rhonda stuff as you'll hear her talk about Later in the episode when she talks about all the new things that she's building for her Website as well so I hope you enjoyed the show this is Doctor Rhonda Patrick Rhonda. Thanks so much for coming back on the show you were actually my very first guest in now. I look back and I'm Almost like forty plus episodes deep. So so thank you for returning totally. Yeah I totally remember that. For the first episode we recorded a few years ago. I was living in New York. I didn't have any babies like you didn't have any babies inch. Definitely things have changed a lot becoming a parent is like the definitely definitely definitely a huge change in the life. Yeah absolutely I'm just now returning getting enough sleep against the things are things are looking up especially for for Dr as well one of the things I want to cover. That has changed since we last talked as you had really gone. Deep and published a paper around the phospholipid form of mega threes and its benefits. I was wondering if you could bring us up to speed on that And what your current thinking is on Omega three supplementation tation so when it comes to talking about phospholipid. Dha When it comes to? Ha in general. D H as one of the Omega threes. He's it's predominantly found in marine sources. Really what I care about is getting it to the brain. That's like my number one interest and and the only type of Dha that crosses the blood brain barrier is Dha that is bound to albumin which is a protein found in your bloodstream? Transports a variety of you know goodies. In addition to Dha to other tissues including the brain but there are two forms of Dha that are bound to albumin and these two different forms are are transported by different mechanisms so the first is Dha that is not as terrified. It's not bound to anything other than albumin. So it's in a free fatty acid form and I often refer to that as Dha free. It's free it's not bound to anything. Aside from albumin eakins transported across the blood brain barrier via this mechanism. That's passive diffusion. which just means? It's you know passively crossing the blood brain barrier and the blood brain barrier. There's there's a variety of things that you know. Make it up but one of the things that's important in this discussion. Is that endothelial cells. Line the blood brain barrier and there the endothelial cells are attached to each other by tight junctions so this passive diffusion mechanism where free. Dha gets across the brain. Rain depends on the integrity of the blood brain barrier so unfortunately as we age the blood brain barrier becomes compromised and this is even more of an issue in people that have an April e four wheel April four is just a a gene and a Lille just means you know one copy of the gene when you have two copies of every gene one from your mom. When from Your Dad's we have to a- liles of every and just bring people up to speed if you have one copy of this gene? Your how much more likely to get Alzheimer's numbers as people that have one copy of the four wheel are about to twofold more likely to get Alzheimer's disease and people that have no copies of it. People people who have two copies of it. It's not very common so about twenty. Five percent of the population has at least one copy of it to copies much much less common. I don't know the percentage off off the top of my head but you can figure the math out. You know twenty five percent. Has One copy what you now. Two copies would be that increases the risk for Alzheimer's disease from anywhere between ten and a fifteen fold in. What percentage of the population that is diagnosed with Alzheimer's disease has at least one copy anywhere between sixty five to eighty five percent? Wow Yeah so this is a pretty big indicator then it is and we could spend like ours talking about the reasons why that is and I do talk a lot about that in my paper paper that published last October in Facet Journal but basically to get back to the whole. Dha Part of the story. I mentioned that. There's two ways it. Can you be transported brain. This one form that's free you know not bound to anything other than albumen. It goes through passive diffusion however April before actually disrupts that because it does compromise compromised blood brain barrier and that even gets worse with age things like traumatic brain injury also compromise the blood brain barrier the good news is there is another form of Dha that is is bound to albumin. It's a form. That is a specific type of phospholipid form called Lice. Oh foster title colon. Dha or Dha Lice OPEC. As I I.

Kevin Doctor Rhonda Patrick Rhonda Rhonda Patrick Alzheimer's disease Alzheimer Metformin Kevin Rose Omega Three Kevin Roche Tim Ferriss Japan Sulfurophane Trajan Facet Journal foreman Dr Peter Tia Lille David Sinclair Volterra Longo
"facet journal" Discussed on The Kevin Rose Show

The Kevin Rose Show

11:39 min | 1 year ago

"facet journal" Discussed on The Kevin Rose Show

"Everybody kept rose here. Welcome back to another episode of the Kevin Rose Show happy twenty twenty a brand new year and so I'm really excited to have doctor Rhonda Patrick on the show because what better way to address in health and longevity in January. It's surely a topic that is on a lot of our minds. I for one. I'm going to try try. Mostly mostly Pasqua -Tarian Diet for this first month and get my blood work checked and see what it does to some of my numbers I'm also going to be cutting out drinking drinking for the most part because I have a plan to Japan at the end of the month I will be drinking in. Japan will be having Saturday and good Japanese beer but the first few weeks they will not have any any drinks and get by blood tested before all of that anyway. Doctor Rhonda Patrick is one of my favorite scientists. She goes in reads leads. All the published studies around health and longevity and really takes that information out of there that is too technical for the average person to understand and then translates slates it into things that we can incorporate into our everyday lives. This is the best way to get your health advice. People like doctors are always always four five ten years behind except for some Dr Peter but but the average doctor is is many years behind what the science is actually telling us to do. So if you want to know the latest and greatest it's best to go to scientists and thankfully do to podcast. Ron has a fantastic podcast and also a great website called foundmyfitness.com. She has been able to give us that direct link to scientists and so she interviews a bunch of great scientists and really help help us make better decisions earlier on so for example in this episode. We talk about mega threes. Why they're not all created equally and there's various this different forms of Omega Three? We talk about which ones that she takes. How much she actually takes personally? Lots of great information there because not only is she Understanding understanding the science to relate to us but also has published her own science around mega threes. And she's done a bunch of research in regards to make it through his impact on dimension in Alzheimer's so great to half talking about that we also talk about metformin which is very hot drug right now hot. I don't know if he can call a drug hot. But it's a very very popular drug at least in Silicon Valley For people take into extend life and some of the potential pitfalls that it has we also talk about a compound called so for vein gene which is found in Broccoli. She talked about at length on her own podcast about sulfurophane but there is some new data out there that we cover we also talk talk about a new brand of sulfur fame that she has imported that she takes so a lot of interesting stuff. There we cover sauna usage. Some new studies have come out there so a lot of really new things to chat about in this was a great episode. I really enjoyed it and I know that you will too so happy. Twenty twenty cheers to you really hoping that all of us happy and healthy this year Introduced some new healthy habits into your life and Hopefully subscribe to all of Rhonda Duffy as you'll hear her talk about later in the episode when she talks about all the new things that she's building for her website as well so I hope you enjoyed the show this is doctor. Rhonda Patrick Doc Rhonda. Thanks so much for coming back on the show you were actually my very first guest in now. I look back. And I'm almost like forty plus episodes deep so so thank you you for returning a totally. Yeah I totally remember that. For the first episode recorded a few years ago I was living in New York. I didn't have any babies like you didn't have any babies excite change definitely. Things have changed a lot. Becoming a parent is like the the definitely a huge change in the life. Yeah absolutely fluently. I'm just now returning getting enough sleep against the things are things are looking up especially for for Doria's well one of the things I wanted to cover. That has changed since as we last talked as you had really gone deep and published a paper around the phospholipid form of Omega threes than its benefits. I was wondering if you could bring us up to speed on that And what your current thinking is on Omega three supplementation so when it comes to talking about phospholipid. Dha When it comes to DHA General D H as one of the Omega threes? It's predominantly found in marine sources. Really what I care about. Is You know getting it to the brain. That's like my number one interest and the only type of Dha that crosses the the blood brain barrier is Dha that is bound to albumin which is a protein found in your bloodstream? Transports a variety of goodies. In addition to Dha to other tissues including the brain rain but there are two forms of Dha that are bound to albumin and these different forms are transported by different mechanisms so the first is Dha that that is not as terrified. It's not bound to anything other than albumen. So it's in a free fatty acid form and I often refer to that as Dha a free it's free it's not bound to anything. Aside from albumin. It gets transported across the blood brain barrier via this mechanism. That's passive diffusion. and which just means it's you know passably crossing the blood brain barrier and the blood brain barrier. There's a variety of things that you know. Make it up but but one of the things that's important in this discussion. Is that endothelial cells. Line the blood brain barrier and they're the endothelial cells are attached to each other by lied tight junctions so this passive diffusion mechanism. Where'd free? Dha gets across the brain depends on the integrity of the blood brain barrier so so Unfortunately as we age the blood brain barrier becomes compromised and this is even more of an issue and people that have an April four L. E. L. April four is just a gene and A Lil just means one copy of the gene. You have two copies of every gene one from your mom one from Your Dad's we have up to a liles of every gene and just bring people to speed if you have one copy of this gene. Your how much more likely to get Alzheimer's Disease People that have one copy of the April. Four ELEO are about to twofold more likely to get Alzheimer's disease and people that have no copies of it people that have two copies of it. It's not very common so about twenty five percent around. The population has at least one copy of it to copies much much less common. I don't know the percentage off the top of my head but you can figure the math out if you know. Twenty five percent has one copy what you know. Two copies would be but that increases the risk for Alzheimer's disease from anywhere between ten to fifteen fold in. What percentage of the population that is diagnosed? Those with Alzheimer's disease has at least one copy anywhere between sixty five to eighty five percent. Wow Yeah so this is a pretty big indicator then it is and we could spend hours talking about the reasons why that is and I do talk a lot about that in my paper that he published last October in Facet Journal but but basically to get back to the whole. Dha Part of the story. I mentioned that there's two ways it can be transported brain. This one form that's free you know not bound to anything other than albumin. It goes through passive diffusion however April before actually disrupts that because it does compromise the blood brain barrier and that even gets worse with age things like traumatic matic brain injury also compromised barrier. The good news is there is another form of Dha that is bound to albumin. It's a form that is a specific type of fossil so lipid form called Leisa foster title Coleen Dha or Dha Lice OPEC as. I like to call it for short. And that's also transported across the blood brain barrier through an entirely different mechanism uses a transporter called. MFS D to a and basically when this phospholipid form of Dha binds to the transporter the transporter flips it across the outer membrane into the inner membrane of the blood brain barrier potentially bypasses any defects for example apple in tight junctions. NFL's just mentioning. which by the way April before does disrupt tight junctions in lining the blood brain barrier? So I sort of argue in my latest publication that this specific Dha Lice O.. P. C. Form of Dha may be a nice way to bypass that defect that April before it causes or even just normal brain aging causes where you can get Dha into the brain is. Does your hypothesis here. That lack of this. Dha is a cause potential cause of of dementia yet specifically making people with April four more susceptible to it so Dha plays a lot of important roles in the brain. It plays a role in preventing and ameliorating a couple of the hallmarks marks associated with Alzheimer's Disease Tangles and Amyloid Beta plaques and that's been shown in clinical studies it's been shown that Dha supplementation. Can Dan lower the amyloid burden. And also tangle pathology in people have them so specifically people with Alzheimer's disease and it also can improve cognitive function The other thing that. Dha does it's really important for transporting glucose across the blood brain barrier and this is a really really major hallmark of Alzheimer's Disease Not Getting Glucose into the brain. Basically that is actually something that can be observed before any other clinical features of Alzheimer's disease and it's specifically specifically found early people with April four so DHA's important for increasing levels of the transporters that transport glucose across the blood brain barrier the glucose transporters. So I I always thought that you know people for a while. We're calling dementia or Alzheimer's disease like potentially type three diabetes ladies. I'm sure you've heard it called that before I always thought an increase. Too Much Glucose in the body would be a bad thing but here you're saying the brain getting a lack of glucose is the bad thing what I'm saying here. Yeah is that getting not having glucose in the brain can be a bad thing. But that's separate from obviously from like district. Blood Blood Glucose I levels and insulin insensitivity lick. Those things are all hallmarks of aging and cause multiple multiple problems for sure. It's kind of a different thing that I'm talking about here So like brain glucose levels are important for preventing a lot of the the hallmarks associated with Alzheimer's disease. And this has to do with with a lot of like very specific molecular mechanisms having to do with like forming cow tangles and stuff like that so not being able to get glucose into the brain can play a causal roll out hammers disease. And perhaps that is also linked to this type three diabetes that you're referring to that would be you know a completely separate but sort of a parallel mechanism Gotcha. Dha I think it could play a role in addition rice or Dha is important for getting glucose in the brain but also some new research does indicate that you know insulin. Insensitivity can reduce glucose getting into the brain as well so those things could even possibly center. Dr Dr who knows I mean it'd be nice to see data on that but in terms of getting the and the brain and like the question you kind of asked at the beginning. I'm and I'm sure people are wondering is like what what are the dietary sources of these different types of Dha the free Dha versus Lice OPEC Dha the one that's phospholipid form..

Alzheimer's Disease Coleen Dha Doctor Rhonda Patrick Alzheimer Japan Rhonda Patrick Doc Rhonda Rhonda Patrick Rhonda Duffy Kevin Rose New York Dr Peter Ron metformin Dr Dr Doria Facet Journal OPEC apple L. E. L.
"facet journal" Discussed on The Kevin and Ryan Show

The Kevin and Ryan Show

11:39 min | 1 year ago

"facet journal" Discussed on The Kevin and Ryan Show

"Everybody kept rose here. Welcome back to another episode of the Kevin Rose Show happy twenty twenty a brand new year and so I'm really excited to have doctor Rhonda Patrick on the show because what better way to address in health and longevity in January. It's surely a topic that is on a lot of our minds. I for one. I'm going to try try. Mostly mostly Pasqua -Tarian Diet for this first month and get my blood work checked and see what it does to some of my numbers I'm also going to be cutting out drinking drinking for the most part because I have a plan to Japan at the end of the month I will be drinking in. Japan will be having Saturday and good Japanese beer but the first few weeks they will not have any any drinks and get by blood tested before all of that anyway. Doctor Rhonda Patrick is one of my favorite scientists. She goes in reads leads. All the published studies around health and longevity and really takes that information out of there that is too technical for the average person to understand and then translates slates it into things that we can incorporate into our everyday lives. This is the best way to get your health advice. People like doctors are always always four five ten years behind except for some Dr Peter but but the average doctor is is many years behind what the science is actually telling us to do. So if you want to know the latest and greatest it's best to go to scientists and thankfully do to podcast. Ron has a fantastic podcast and also a great website called foundmyfitness.com. She has been able to give us that direct link to scientists and so she interviews a bunch of great scientists and really help help us make better decisions earlier on so for example in this episode. We talk about mega threes. Why they're not all created equally and there's various this different forms of Omega Three? We talk about which ones that she takes. How much she actually takes personally? A lot of information there because not only is she Understanding understanding the science to relate to us but also has published her own science around mega threes. And she's done a bunch of research in regards to make it through his impact on dimension in Alzheimer's so great to half talking about that we also talk about metformin which is very hot drug right now hot. I don't know if he can call a drug hot. But it's a very a popular drug at least in Silicon Valley For people take into extend life and some of the potential pitfalls that it has we also talk about a compound called so for vein gene which is found in Broccoli. She talked about at length on her own podcast about sulfurophane but there is some new data out there that we cover we also talk talk about a new brand of sulfur fame that she has imported that she takes so a lot of interesting stuff. There we cover sauna usage. Some new studies have come out there so a lot of really new things to chat about in this was a great episode. I really enjoyed it and I know that you will too so happy. Twenty twenty cheers to you elam really hoping that all of us happy and healthy this year Introduced some new healthy habits into your life and Hopefully subscribe to all of Rhonda Duffy as you'll hear her talk about later in the episode when she talks about all the new things that she's building for her website as well so I hope you enjoyed the show this is Doctor Rhonda Patrick Doc Rhonda. Thanks so much for coming back on the show you were actually my very first guest in now. I look back. And I'm almost like forty plus episodes deep so so thank you you for returning a totally. Yeah I totally remember that. For the first episode recorded a few years ago I was living in New York. I didn't have any babies like you didn't have any babies excite change definitely. Things have changed a lot. Becoming a parent is like the the definitely a huge change in the life. Yeah absolutely fluently. I'm just now returning getting enough sleep against the things are things are looking up especially for for Doria's well one of the things I wanted to cover. That has changed since as we last talked as you had really gone deep and published a paper around the phospholipid form of Omega threes and its benefits. I was wondering if you could bring us up to speed on that And what your current thinking is on Omega three supplementation so when it comes to talking about phospholipid. Dha When it comes to DHA General D H as one of the Omega threes? It's predominantly found in marine sources. Really what I care about. Is You know getting it to the brain. That's like my number one interest and the only type of Dha that crosses the the blood brain barrier is Dha that is bound to albumin which is a protein found in your bloodstream? Transports a variety of goodies. In addition to Dha to other tissues including the brain rain but there are two forms of Dha that are bound to albumin and these different forms are transported by different mechanisms so the first is Dha that that is not as terrified. It's not bound to anything other than albumen. So it's in a free fatty acid form and I often refer to that as Dha a free it's free it's not bound to anything. Aside from albumin. It gets transported across the blood brain barrier via this mechanism. That's passive diffusion. and which just means it's you know passably crossing the blood brain barrier and the blood brain barrier. There's a variety of things that you know. Make it up but but one of the things that's important in this discussion. Is that endothelial cells. Line the blood brain barrier and they're the endothelial cells are attached to each other by lied tight junctions so this passive diffusion mechanism. Where'd free? Dha gets across the brain depends on the integrity of the blood brain barrier so so Unfortunately as we age the blood brain barrier becomes compromised and this is even more of an issue and people that have an April four L. E. L. April four is just a gene and A Lil just means one copy of the gene. You have two copies of every gene one from your mom one from Your Dad's we have up to a liles of every gene and just bring people to speed if you have one copy of this gene. Your how much more likely to get Alzheimer's Disease People that have one copy of the April. Four ELEO are about to twofold more likely to get Alzheimer's disease and people that have no copies of it people that have two copies of it. It's not very common so about twenty five percent around. The population has at least one copy of it to copies much much less common. I don't know the percentage off the top of my head but you can figure the math out if you know. Twenty five percent has one copy what you know. Two copies would be but that increases the risk for Alzheimer's disease from anywhere between ten to fifteen fold in. What percentage of the population that is diagnosed? Those with Alzheimer's disease has at least one copy anywhere between sixty five to eighty five percent. Wow Yeah so this is a pretty big indicator then it is and we could spend hours talking about the reasons why that is and I do talk a lot about that in my paper that he published last October in Facet Journal but but basically to get back to the whole. Dha Part of the story. I mentioned that there's two ways it can be transported brain. This one form that's free you know not bound to anything other than albumin. It goes through passive diffusion however April before actually disrupts that because it does compromise the blood brain barrier and that even gets worse with age things like traumatic matic brain injury also compromised barrier. The good news is there is another form of Dha that is bound to albumin. It's a form that is a specific type of fossil so lipid form called Leisa fos title Coleen Dha or Dha Lice OPEC. As I like to call it for short and that's also transported across the blood brain barrier through an entirely different mechanism uses a transporter Called MFS D to a and basically when this phospholipid form of Dha binds to the transporter the transporter flips it across the outer membrane into the inner membrane of the blood brain barrier potentially bypasses any defects for example apple in tight junctions. NFL's just mentioning. which by the way April before does disrupt tight junctions in lining the blood brain barrier? So I sort of argue in my latest publication that this specific Dha Lice O.. P. C. Form of Dha may be a nice way to bypass that defect that April before it causes or even just normal brain aging causes where you can get Dha into the brain is. Does your hypothesis here. That lack of this. Dha is a cause potential cause of of dementia yet specifically making people with April four more susceptible to it so Dha plays a lot of important roles in the brain. It plays a role in preventing and ameliorating a couple of the hallmarks marks associated with Alzheimer's Disease Tangles and Amyloid Beta plaques and that's been shown in clinical studies it's been shown that Dha supplementation. Can Dan lower the amyloid burden. And also tangle pathology in people that have them so specifically people with Alzheimer's disease and it also can improve cognitive function The other thing that Dha does it's really important for transporting glucose across the blood brain barrier and. This is a really really major hallmark of Alzheimer's disease. Not Getting Glucose into the brain. Basically that is actually something that can be observed before any other clinical features of Alzheimer's disease and it's specifically specifically found early people with April four so DHA's important for increasing levels of the transporters that transport glucose across the blood brain barrier the glucose transporters. So I always thought that you know people for a while. We're calling dementia or Alzheimer's disease like potentially type three diabetes ladies. I'm sure you've heard it called that before I always thought an increase. Too Much Glucose in the body would be a bad thing but here you're saying the brain getting a lack of glucose is the bad thing what I'm saying here. Yeah is that getting not having glucose in the brain can be a bad thing. But that's separate from obviously from like district. Blood Blood Glucose I levels and insulin insensitivity lick. Those things are all hallmarks of aging and cause multiple multiple problems for sure. It's kind of a different thing that I'm talking about here So like brain glucose levels are important for preventing a lot of the the hallmarks associated with Alzheimer's disease. And this has to do with with a lot of like very specific molecular mechanisms having to do with like forming cow tangles and stuff like that so not being able to get glucose into the brain can play a causal roll out hammers disease. And perhaps that is also linked to this type three diabetes that you're referring to that would be you know a completely separate but sort of a parallel mechanism Gotcha. Dha I think it could play a role in addition rice or Dha is important for getting glucose in the brain but also some new research does indicate that you know insulin. Insensitivity can reduce glucose getting into the brain as well so those things could even possibly center. Dr Dr who knows I mean it'd be nice to see data on that but in terms of getting the Dha and the brain and like the question you kind of asked at the beginning. I'm and I'm sure people are wondering like what what are the dietary sources of these different types of Dha the free Dha versus Lice OPEC Dha the one that's phospholipid form..

Alzheimer's Disease Coleen Dha Doctor Rhonda Patrick Alzheimer Japan Doctor Rhonda Patrick Doc Rhon Rhonda Patrick Kevin Rose New York Rhonda Duffy Dr Peter Ron metformin Dr Dr Doria Facet Journal elam NFL apple
"facet journal" Discussed on The Model Health Show

The Model Health Show

04:17 min | 2 years ago

"facet journal" Discussed on The Model Health Show

"This is one of the times of year when they're doing things special for the people that they care about Valentine's tend to be a time that lovers. Go the extra mile for each other right Dana's chocolate cook for them, fellas. Have you ever cooked for your lady as a whole different level right there? Bubble bads rose pedals the people go all out. And when I think about that kind of thing, though, the rose penalties genetic I don't know if they're safe or not but play lists. You might put a playlist together. Have you ever made a playlist for your significant other? You know, one that helps to support the mood. Right. Getting it on. Well, with all of that said every year, I like to do some things around a certain theme in last year around Valentine's Day, I did a really special episode focused on how to increase your level of self love in how your self love impacts, your health happiness and success. And it was one of my all time favorite and most powerful episode. So if you happen to miss that one definitely check it out. It'll be in the show notes for you. But this time for this year. I wanna talk about a subject matter that is often overlooked, but it's a huge part of our overall health and wellness today, we're talking about how sex helps you to live a longer and healthier life. And I think that these studies are straight up going to blow your mind. I so this episode is not for the youngsters. All right. So that should go without saying. But today, again, we need to really make some of this stuff clear because he's studies just blew my mind. And I was so shocked that we don't know more about this. So we're going to have this conversation today, we're gonna talk about sex. Hit me with the little bit of that. So that's what we're getting into today. And again, get ready to take some good notes and just have your your your mind, really shifted your perspective shifted because this is something that we really take for granted. We don't really talk about. So again, I think you're gonna get a lot out of this. But before we do that I cannot have a conversation about longevity because today we're talking about how sex impacts your longevity and you'll see why. But I can't talk about longevity without talking about some nutritional components. There was a study published in the international journal of molecular medicine that found that fruit flies, given quarter sets live thirty two percent longer than the controls who didn't interesting, but that's just fruit flies, right? What about lay mammals or there's another study published in the facet journal that found that mice given court assess lived several months longer than the control group that didn't receive quarterbacks do not have on. That is a mouse years. That's like. That's literally like a few extra years of life. We think about mice. I don't know. Just for me. I think about like master splinter, right? I'm just thinking all their old. They get old whatever. No, not like that additional months means additional years. And so what does this all correlate to publish in the American journal of Chinese medicine found that court protects model Qendra, right? These energy creating power plants in all of ourselves. They protect them by scavenging reactive oxygen species or these are S's. And so this is what's kind of correlated with aging as we see this uptick in inflammation and uptick of this free radical activity kind of a hyper experience of this free radical activity now several human studies have found that cortisol improves cardiovascular function veto to max, insulin sensitivity as well. All right. So long history in also today, we've got so many different clinical studies that are proving the efficacy of court. So if we're talking about longevity, really gotta take a look at this. And so for me in the different studies that I looked at were doing different extracts. They're doing different extraction methods of the cortisol. So this is why I'm a big fan of four Sigmatic is because they do a dual extraction because you hear studies, and you don't know what extraction method or they using..

Valentine cortisol Dana American journal of Chinese me international journal of molec Sigmatic Qendra thirty two percent
"facet journal" Discussed on 77WABC Radio

77WABC Radio

07:24 min | 2 years ago

"facet journal" Discussed on 77WABC Radio

"Is no exception. It's now in ocean caps. Ocean caps is the latest technology. It's a fish capsule. So this is a completely aquatic Paschke -tarian product. It's a million percent aquatic Pesca -tarian of krill and the capsule. Now, I put it in a fish capsule because you can't put krill in gelatin capsule, the krill interaction with gelatin and Nelson. So excuse me, you see I apologize. I said the wrong thing you can't put krill and a vegetable capsule the krill interact with the vegetable cellulose in Melcher. Shall we had no choice, but to use gelatin and people did not want us to use beef gelatine? So I found fish gelatin fish gelatin, twelve ocean cops, but that has specific advantages. Over gelatin the ocean caps have specific advantages one. It improves the bioavailability of the Crowell. And other words, you absorb the krill better. You're going to absorb more to krill faster. More completely you're going to get more benefit from me grow. And to the ocean caps as a very powerful barrier to oxygen as you know, oxygen can make fats go bed at oxidized system. Like butter. It oxidises butter. So fish oils are fat. So putting the krill. It's a little relative of shrimp. Crustacean, putting the krill oil and eve any ocean cap Apache -tarian capsule. Shields it totally solidly from oxygen and approves its absorption now. I would call that great technology, and it's really clean. That's not from a Cal, right? From a fish. By the way, the the fish gelatin is good for your skin. Fish gelatin makes your facial skin better than any other source of protein. So when you take the Criollo capsules you're also getting a nice boost fear facial skin. Now, that's just like added benefit. They found out faulty brain plumbing is partially to blame for blame for Alzheimer's at university of Virginia health system. See about about in about twenty fifteen the year. Twenty fifteen researchers from the university of Virginia and conjunction what Univer researcher from the university of from Trinity College in Dublin found out that your lymphatic system goes directly into your brain. They never noticed before. Irish researchers and soon after working with the university. The researchers in Virginia they found that your lymphatic system goes directly into your brain. And it drains lawf- toxins from the brain. It's called the Glenn fabric system, and they found out a reduction in glum fabric activity. Was a build up of the beta amyloid plaque that eventually rot your brain and causes damage to the nerves and leads to Alzheimer's disease. So they found that krill oil specifically, it's an facet journal does a great job of restoring the fabric system, the drainage detoxification system of your brain, these these organs Bolom fatty tissue that goes directly into the middle of your brain. They run down your spine. So they can actually sheet a plaque leaving your brain. That I found out when they give krill oil eclipse waste products out of your brain. Now, that's important. What you hit about fifty or sixty the ability to remove plaque and toxins from the brain starts to decline. Just like circulation into the brain decreases removing junk from her brain removing Thompsons from the brain. Also decreases. So by taking fish wells or eating fish, you helped us by taking crow. You you help it a little bit more. That's a little bit better at it. And you restore the ability to move to move the plaque out of your brain. It's great. That's great. You're restoring plaque removal and fifty or sixty or seventy year old person to data of like a thirty or forty year old you're detoxifying the brain equivalent to a person thirty to forty. But they found out something else. Freaky about about Alzheimer's. It comes out of deliver. They found out as you grow older. The lever is not able to create as many plasma allergens. It's funny university of Pennsylvania school of medicine. Okay. That's the Ivy league. University of Pennsylvania and Philadelphia's Ivy league. My sister-in-law half their family are doctors that came out of university of Pennsylvania. They know so much. Bright and they're so into medicine, you know. The way some people enjoy tennis golf these people. I mean, it's like me reading research. I enjoy reading researchers much as most people do playing golf. That's a good thing. Because that's how I make a little bit. So it works for me. Okay. Let's get back to it. They found that your liver as you grow older makes less plasma allergens. Now. That's really important. Plasma allergens build bone tissue. Plasma allergens, create brain tissue. They create structures and make the brain work properly. This is really interesting stuff. They found this by. University of Pennsylvania medical school. They were studying veterans and the veterans affair medical center over there in Philly. So they found out. There's no doubt about it plasma login data created an a they're made out of crow. You get a little bit of the sources of plasma allergens in egg yolk egg yolk has some of the sources like it has some teen at has some phospholipids has a little bit of choline. You also get out a dark, meat and chicken. But the best source is krill the best source of plasma. Because you get everything you need you need you need to glacier, a fossil LePage. You need foster titled choline you need choline you need fish oils. They're all found in the grill. All the essential ingredients that deliver puts together to make plasma allergens for your brain are found in krill. Whoa. Casual so this is edit value for krill oil that you're not getting what a regular official capsule. Not only does krill oil restored a glimpse paddock leaching of toxins out of brain, detoxification of the brain it restores plasma plasminogen production in the brain. We'll talk about that. Because that's intimately involved with slowing down of preventing the Alzheimer's process..

gelatin Alzheimer university of Pennsylvania sch Ivy league university of Virginia health Melcher Virginia University of Pennsylvania university of Pennsylvania university of Virginia Alzheimer's disease Crowell golf Thompsons Nelson foster veterans affair medical center official
"facet journal" Discussed on 710 WOR

710 WOR

05:01 min | 2 years ago

"facet journal" Discussed on 710 WOR

"'cause I know it's good for my heart. And I know what you could from my brain. But a social could feel your bones and your muscles. Why it creates plasma allergens? This is one of the reasons why Sochi Brandon's krill oil. Krill oil does a bunch of things for the brain better than fficials. Krill. It's the weight officials are made and the crow krill is a crustacean little tiny speck. That's a relative of shrimp little tiny speck of an organism as so tiny. But when the krill is in the ocean, the ocean turns red because billions of trillions of a mall. That's what the blue wells. The biggest animal that ever lived lifts on krill based on a lover Lewisham crew. And we have ours from a sustainable fishery. It's not a problem. There's plenty of krill of over for the penguins and the sea lions and the blue the blue whales plenty. If there wasn't I wouldn't make. So it's a sustainable fishery. A friend of the certification. So krill. More. So than fficials is good for the brain and good for the heart. By the way to officials and krill been known to lower the risk of breast cancer about twenty four percent. And they also help keep your bones strong the platform for building bone is a structure called plasminogen krill is the best source supplies. Melgen ingredients watching Quillet makes plasma fficials glycerin phospholipids foster title, choline calling. They're all in krill oil. There's a structural part of the body. That was only discovered rather recently called plasma. You could get a little bit of the ingredients to make this from egg yolks or chicken. But you get a lot from krill. You get a little bit from Fisher student kept me rock, you get a lot more from crew krill is the best source. Krill or ocean? Scallops the big scallops day also help. Now krill has all these things started rather amazing for the brain it as glycerin phospholipids. They allowed a brain to think and to remember and to learn because they help create acetylcholine acetylcholine is memory neurotransmitter. They help you release Gaba at the appropriate time and glutamate at the appropriate time. She can learn and acetylcholine she can remember. I mean, the krill does done because choline in it and it foster title choline and it has foster title sharing. All these things are involved with memory. But krill also stimulates the fabric system in the brain. Now. What's that all about? You have a system in the brain. It's made out of lymphatic tissue kind of like a shadow circulatory system. Lymphatic lands go right up your spine. Right. T- deep into your brain and remove plaque and toxins. They remove plaque and talk the glum. Fatty system was first discovered by scientists at university trinity university in Dublin and the university of Virginia back in two thousand fifteen. So it brings the immune system right into the heart of the brain. But also it removes toxins. It breaks down the plaque that builds up and Alzheimer's and removes it flushes out of your brain. And that's a portent the ability to break down plaque, and detoxification starts to decline in your forties and fifties. So a person who's thirty breaks down any brain plaque removes it on a daily basis much more efficiently than somebody in their fifties. Or sixty. When you take the. Krill. It restores functionality of FedEx system, this is research from. It's an facet journal. And also from the university of Virginia health system's when you take the crow. It buffers the glimp- fabric system and lymphocytic system breaks down that deja cruel of plaque and removes it when you got to build up a plaque is related to Parkinson's disease, and it's related to Alzheimer's disease because ventured a plaque poisons and destroys your brain cells, and you have Alzheimer's. But that's one benefit of krill. When we come back. We're going to talk about a second incredibly important benefit of krill for your brain, which is above and beyond. What the Fisher was gonna chief. That's why I believe in krill. I love fish oils. I just think role is a better choice. You get added.

plasminogen krill Alzheimer Fisher university of Virginia Brandon acetylcholine FedEx Quillet Lewisham university trinity university Alzheimer's disease Parkinson's disease Dublin twenty four percent
"facet journal" Discussed on Good Life Project

Good Life Project

02:05 min | 3 years ago

"facet journal" Discussed on Good Life Project

"Join the movement and we are back with this week's good life science update for those of you who are new to the podcast pretty much every week we sneak in assigns update i'm a bit of a geek citizen scientists and i love diving into and keeping up on research that in any way shape or form effect your ability to live better life sometimes it's about health environment work all sorts of different stuff also tend to geek out on stuff that affects our body at a specially are pouring millions and i'm really fascinated with how the we we move our body and the things that we can affect our brains or cognitive abilities or state of mind this week were bringing you a study that was done out of loma linda university and recently presented at experimental biology 2017 meetings in san diego and published in facet journal now what is all that meanwhile if you want to go into the details of this we always include in the show notes so check it out in the show notes a direct linked to the fuller study report for fellow geeks like me who want to athlete look at the uh the research deconstructed see what the experimental design was and try and better understand what's going on my job here is simply to share the simple realizations and awakenings from this week we are talking about nuts and your brain so when we talk about nuts the nuts eat than at a crew from the ground and are part of your diet you may be aware that there's been a fair amount of research done on how those may affect your physiology health your inflammation all sorts of different things it turns out that your of course barring any allergies or a unique reactions at you may have that very often nuts can be considered a very important part of a healthy diet and they have a lot of benefits on you and your physiology your disease risk stuff like that this study ashley looked at whether.

loma linda university facet journal ashley san diego