34 Burst results for "Esters esters"
Ceremony formalizes tribal relationship with Kennewick
"The nez perce tribe reclaimed ownership of property from the united methodist church and a small ceremony thursday as emily swing reports. It's been more than one hundred and forty years since the tribe held rights to that land. Roughly forty people gathered for a small land. Transfer ceremony in will allow oregon nez perce tribal chairman shannon wheeler ended the deed to the property. The ceremony was broadcast live on facebook. This land and our people being forced off of this land and the tears of sorrow as we left today if you shed a tear. That's okay because they're tears of joy now and so are are tears of joy in our happiness today will also be felt by them are as esters in passed in eighteen. Fifty five nez perce chief. Joseph signed a treaty with the us government that granted millions of acres of land to the tribe but twenty years. Later the us army drove the nez perce from that same land. The nez perce are also known as the nemi. Pu people reverend karen hernandez is the district superintendent of the united methodist church in eastern idaho and southern oregon. She handed over keys to a now closed. Methodist church that sits on. What's now nez perce. Land and willa proved people in a gracious spirit of friendship are willing to meet us here as we take this small step toward justice. It blesses us knowing that land that methodists made good use of here but it was never rightfully ours. It is now most rightfully yours. This is the second land transfer from the united methodist church. Three years ago the tribe took ownership of one and a half acres along the lower river. Where the church held retreats for national native news. I'm emily swing
The Jewish Story - Six Day War, Something Miraculous
"I ask you to list. The three biggest miracles in jewish history. What would you say split the red sea plague of the firstborn the mono- sinai. Maybe you get a little more subtle and offer me highlights esters rise to her place in the palace but how many people listening right now would mention operation mccade the critical turning point in the battles of the six day war that we're going to speak about in a bit of detail in just a moment not simply throwing it out there in order to set the stage for what's to come. I'm giving it as an opportunity to contemplate. What exactly a miracle might be the work for miracle in hebrew is this and it has more than one meeting classically. Like i said if you ask person what's a miracle they'll start listing off the sort of cataclysmic events of the biblical narrative. They might also start talking about what we call the hidden miracles or the more subtle expressions of god's hand in their own lives but i think the deeper meaning of miracle comes out when we look at its other definition in the hebrew language in nasa's and just a miracle it's also a flagpole or a sign. It's something which is lifted up beyond the horizon in which we normally dwell. I mean after all in the battle or in frankly in the american national anthem. What is a flag on the battlefield other than a reminder of that which you're fighting for which lies above the plane of struggle it didn't occasion that there's a broader horizon with in which the events of our lives are taking place.
Is Astra the wrong vaccine for border workers?
"One of the big milestones we had about yesterday. Was that the oxford astrazeneca vaccine. I devices of that have arrived in australia. Which is something that we've been waiting for. We're in phase one of the role at at the moment and those are the priority people. And i thought that those people were getting the fis at shot. But now we've got the oxford esters shut here. Are they going to be getting that as well and should they be getting that as well. We're in the press release from the prime minister and the minister. They say that they will guess. That's what they say in the press release and in fact the minister himself a week or so ago a press conference said the same thing that there would be a mix of these vaccines and the trouble with. That is an an accord. Chris murray who ahead on seven thirty last monday which he was. Who's the head of the institute for health. Metrics evaluation in seattle is. That astra is the wrong vaccine. If you're looking at borders let's pull back a little bit about what you're trying to achieve and your vaccine strategy are vaccine strategy is really for a country that has lots of covid around in the middle of covid outbreak. Because you want to partake. H care quite rightly aged care. Workers quite rightly you want to get in there and then you want to protect the rest of the population you want to. Doctors nurses people who work in hospitals all that nor question and we still want to do that but if the virus gets in through the borders that's how the virus gets seen it doesn't suddenly pop aged care home or residential care or pop up in the alfred hospital in melbourne. It comes from overseas. We'll come back to the new zealand situation currently in a minute. So the total strategy in the first instance should be about the borders if we can keep our borders secure. The virus won't get in and then we've got time to immunize for safety reasons. The rest of the population and so astro is the wrong vaccine for. That is not the wrong vaccine. I'll get. I want to say up front. I will get the astro vaccine. I'll be happy to get it. It will protect you in severe disease. But it won't necessarily protect our borders. It will against probably against the uk variant. It's not going to protect almost certainly against us at african variant which only showed ten percent efficacy against. We don't know what is going to do against the brazilian variant which shows vaccine escape. And there's the california variant in american various which. Look as if they might be a bit vaccine resistant themselves and so what we should be doing is saying well astra's fine and the scottish artist suggests it's fine for preventing severe disease but that's for a country that we should be covered getting in the first place. So that's about the pfizer vaccine because it stops transmission. More effectively than the astra zeneca vaccine. I it works within three weeks. You don't have to wait. Three months for the efficacy. Second reason is that moderna there is no. There are no data drawn. Skerritt said on chronic is last week for pfizer. But it's almost identical vaccines to madeira and moderna reasonable efficacy against the south african vary not great but much better than ten percent and and it gives stronger immunity faster so for our borders we should be using pfizer and getting quick protection and we should be protecting their households. Because where's it gonna go after they get infected should he be infected. And if it's the south african is going to go to members of their households at a higher chance so their families or flatmates should be immunized with pfizer to and then the third thing that we should be doing which nobody's talking about just wondering why not but when i talk and by the way this is not necessarily me talking actually sounded out on people who know what they're talking about who aren't where willingness to publicly contradict the government. They say es actually what we should be doing and it's largely what new zealand is doing. They are immunizing. their hotel. boorda workers and their immunizing their families. They've had an outbreak which will come to in a minute. The other thing we should be doing is actually having a forward strategy. Which is if you want to get back into australia. Get immunized and we should help them so some vaccine doses could go overseas to australia. Scott send send it over to make sure the co chain right to our consulates and remember. Pfizer is not quite as temperature sensitive as people say. It's it's a problem once you've dominated you've got to get rid of it but it's not quite temperature sensitive as can last for a while so if you're an australian in london paris and new york senate to this german embassy or their physicians. They've got doctors attached and immunize streams. Get them to pay for. It is cheaper than a hotel quarantine and so you. Don't get on the plane until you've had two doses and you waited another two weeks so you're fully immunized
Skincare Journey with Michelle Lee
"Today we have a guest that iconic doesn't even begin to describe it I feel like we have to get into this. Yeah. I. Mean as per usual who wants to hear from you and I were disgusting trolls we have to. Fight. The woman who is here today? It's potentially going to change all that today. No promises, but baby. Today we have on the editor in chief that's e I see. Okay. That's industry slain of Allure magazine. Honey it's Michelle. Lee. You guys this is Michelle welcome to the show I am so starstruck grew up reading magazines on Friday nights. So the fact that I'm speaking to an actual editor in chief I just I'm like Holy Shit like she's she knows it all she has I'm so cluttered what an introduction and I don't want against her up too much. But please if I may gas a little more. This woman the. Incomparable Michelle Lee. Has worked at some of your favorite magazines not only are you the editor in chief of a law, which is like unbelievable I'm salivating I have. I'm Fan girling your editor in chief of nylon correct I was I was that was my job right before Lor and for that you've worked for Britain for like a million zillion different publications glamour you are on the founding team of I want to say COSMO Girl Yep. Yeah. Do you remember Cosmo girl? Do I S- I was the third higher at Cosmo girl. We created the sticker is we did the whole thing. So no innovative remember what magazines used to have stickers. I just thought about member lucky I mean, of course, Michelle, you remember Lucky magazine of course, the stickers I love serious by it. It was like they had like three options. It was like I think about it don't buy. Could you imagine like going through your magazine and being like I'm not going to buy that can put a sticker next to it. That sounds so fun. Anyway Michelle. You've seen it all you've written for it all and you know so much about beauty and we're so honored to have you on our show. Well, I am so honored also because I am a gloomy I'm a huge fan I seriously has done a whole marathon literally almost every single episode and I could listened I talk about you guys all the time I do like in the office attack about you to other people I'm obsessed I'm also. So embarrassed of all the things united me right now so Let. On, sorry yeah. Learn a lot about La 'cause I don't know that much about L. A. Things. So like Erawan, I feel like I've learned so much about oat milk from you guys. You would think there's not that much to learn when it comes to oats and water mixed together but. Lord knows Esther and I. Found the crevices and like some. A lot of stuff to talk about when it comes to. You wouldn't gosh I'm fan growing and I'm embarrassed I mean Michelle you know too much about ministers bodies. That my worst. About. Yeah. I I'm speechless. We had to make good use of this time her okay. So Let's just start by talking about. Your instagram which I really recommend everyone go follow I. Believe it's Hey. Michelle Li Yep. Your instagram is a treasure trove of so much stuff your interests when it comes to beauty or far-ranging particularly I, feel like what? I think of Michelle, Lee think of nail art and ask for. Today was staring at your nail since meeting. Oh good podcastone. SURPRI-? I'm so genuinely minor Kinda. Jenky like don't look through closer little crumbly idea your on. Let me say I who I do my own nails. You'll notice. They, look cute Think-i esters. Got Some. Cutie I do I started doing at sea press on meals? And I'm a I'm enjoying myself I'll say, Oh, you know I did press on nails for the first time recently Chill House No Chill House released on. It's very cool salon in New York. City, and they have I think they used to have two locations there now down to one and they just made these very cool press but they're very like a lot of the nail art that I have my instagram. They have as well because I get my nails there quite a bit but they're cute cute like really minimalist. Designs. Oh. I. Love that one you posted of the Purple Marble yes. That video is so cool. Yeah. I. It's like I do a lot of reposting of other nail artists to and I went down this rabbit hole of Russian. Nail artists are next level like the way that they do marble nails and other things. It's just like stuff you've never seen before.
How Do Glow Sticks Work?
"Brain stuff. This is Christian Sagar you have seen glow sticks before I. Bet they bring a festive glow to Halloween trick or treating and New Year's eve celebrations, and they are a useful gear for explorers from scuba divers to spinnakers. When you find a bunch of people gathered at a party in the dark at least a few of them will probably be wielding glow sticks. But what the heck are these things and how do they work? Well, glow sticks are powered by process called Cama luminescence don't let the name scare you luminescence is just a fancy word for any emission of light not caused by heating we see luminescence and stuff like TV's neon. Signs and firefly's the chem luminescence in glow sticks is a pretty simple reaction caused by mixing chemical compounds. Compounds are made up of different elements bonded together in specific proportions so that they can't be mechanically separated. It takes a chemical reaction to sort out for example, the oxygen from the hydrogen and water. When you mix a compound with other stuff, you can set off that reaction and as the atoms rearrange themselves either absorb all release energy. If you look inside a glow stick, you'll see that there's a small glass vile in the tube. This file typically contains a hydrogen peroxide solution called the activator it's floating in a solution containing a compound called phenyle oxalate. Ester and a fluorescent dye you still with me. Okay. When you snap a glow, stick the vial breaks in the Hydrogen Peroxide reacts with the phenyle oxalate Ester creating to other compounds phenyle and a pair oxy acid ester. Okay. Still with me again. Okay. This para oxy acid stuff is unstable. So it decomposes and produces additional finol. It also produces a cyclic Perry compound which decomposes to carbon dioxide. This decomposition releases energy to the die the electrons in the atoms jump to a higher level than fall back down releasing energy in the form of light the other in the fluorescent dye, determine the color of this light all this happens within moments of snapping. And shaking your glow stick depending on which compounds are used, the chemical reaction can continue for anywhere from just a few minutes to hours warmer temperatures will accelerate the reaction making the stick glow brighter. But for a shorter amount of time when it's cooler, the reaction will slow down making the light dimmer, which means that if you want to preserve your light stick, put it in the freezer overnight, it won't stop the process, but it will slow it down and drag out the reaction. So it turns out that there's some pretty nifty science behind the humble glow stick check it out the next time you're scuba diving partying or you know whatever it is you.
"esters " Discussed on Ben Greenfield Fitness
"Using like a magazine or calcium lactate pre-workout to enhance the activity of of lactic acid, buffering enzymes before like a really anaerobic workout to allow you get less burned pre-workout saying what you that you might use sodium bicarbonate loading pre workout. Yeah so yeah. Sodium buffering is yeah. It's like by car or buffering is an interesting topic, and I think that actually actually ties into uses of exotic. Keaton's for acute workout. There's actually a really really recent study published around looking at potentially the flow of electrolytes winner, and he told US versus not right and I think this might make sense to people that have done a lot of fast. Diet where as insulin reduces, excrete sodium. Do you need more sodium? For example so there's a also interesting parallel to how you actually use that in conjunction of ketone extras for example. The last point I wanted to touch on was the interest in I think important area of research which is cognitive impairment TBI's What happens when the brain? Brain injury or a concussion is that does a catecholamine release the gentlemen everything dumps. You have a hyper metabolic state for all the sugar is used up and then one important enzyme pyro pyro, dehydrogenation, which is the enzyme that Converts Glucose Indepedence H or pirate into Seco as a cycle that enzyme, that's a that gating factor of glucose uptake in the brain is actually inhibited to all of oxidative stress and an area that I'm excited about is what happens in that post, traumatic brain injury brain state. Obviously acute damaged there. You can't repair. Things are just shattered, but what happens is that if you actually look at the brain after he is very very low energy, because no clue, 'cause can be utilized in the brain. Actually look at the Post. Hebron versus the Pre Tea Banh is literally like huge fractions of difference between the amount of energy being consumed in the brain, so it's interesting. Can you go around Ph? Can you go round glucose pathway to feed these starving neurons with other substrates like itunes like lactate and again they work in similar ways where they're not ph limited. And it also has interesting implications for neurological conditions like. Alzheimer's Dementia. I know that there's you know. There's researchers like Steven Khoo Nain in Canada, than looking at agents for this use case as well as efforts at the NIH looking at this applications well so very interesting early, but promising research threads yeah I a few little anecdotes to to throw in there I can definitely attest to the fact that in in terms of not just management of TB. I all clear-headedness on a busy day. You know I've been experimented quite a bit with hyperbaric oxygen therapy as a matter of fact during this this corona virus. Corentin I have been in my own little soft-shell. hyperbaric chamber every single day and I have experimented dosing with Kito nesters prior, and you come out of the hyperbaric chamber with a great deal of clear-headedness, compared to what you would achieve with doing HBO OT in the absence of Ketone, astor's and more clear-headedness than what you get from the keystone. Esther is used by themselves so some different interplay between this hyperbaric oxygen therapy, and the use of kitone esters, dictating that I I would imagine the two would be a pretty useful combination for management of something like I even though neither of us are physicians, and no one should misconstrue. This medical advice the other interesting thing. Ju just to close the loop on the lactic acid piece. Is that we we touch briefly on the use of these these lactates supplements pre workout and I should note that the prevailing amount of research shows that the do indeed not seem to work for for buffering to an extent where a an athlete able to perform better with high intensity bursts of exercise, however, sodium, bicarbonate, or baking soda still stands out as the best way to buffer lactate. Now that being said I know that there is good evidence out there that the supplementation of Ketone esters lowers blood, lactic, acid, and so. What I'm curious about based on this then Jeff is, have you come across anyone who has done something like stat sodium, bicarbonate and Kito Nesters pre workout. You're a smart man Ben. People are exploring that and I would say that some people consider that kind of trade, secret or proprietary. This is how we. have an advantage to our competitors. Of what I will say is that. You're exactly right. There's actually an interesting effect of esters on blood P., p., H., blood, acidity, and We'll see if there's published research coming in the next couple of months. That described that. But it's been exactly thinking the right way. You're controlling a system. Keeping esters offer a novel tool into that system. There's pros and cons, but can you using something like bicarbonate balance out some of the? Acidity when you have high keyed engineer blood. I will I. Will, we'll start seeing published literature on that very very shortly. and and just so you guys know that the problem that researchers always run into and using sodium bicarbonate as something that you would dose with pre workout is that it can cause a a a a steep intake of a fluid volume into the bowels and result in diarrhea. And Diaper Pants pre-workout, and so the trick and the, and this is what most people found through experimentation, and is now being used in some research studies is you do little micro doses? It lets you plan on doing a workout at six PM. This be a tough workout. Maybe you're like Jeff, go. Crush Murph or you've just got some super intense coming up or even a race or competition, what you do is for the two hours leading up to that competition every twenty minutes, or so like have a little bit of water. You know like four answers or so of water, and just put like the tip of Teaspoon of baking soda into each glass of water. You know we're taught that it. It probably comes out to somewhere close to a grammar so. And that actually mitigates a lot of those effects of doing like a large bullets of baking soda like. Twenty to thirty minutes pre workout so that that's a strategy that seems to work and I would imagine that combining that with like a dose of Ketone esters. Then you know twenty to thirty minutes prior to that workout. As part of that scenario would actually be a pretty good lactate, but what is the only thing I could think of throwing in if we're going to stack these type of things would be. There's a lot of evidence now on Karna seen in Carnoustie's lactate buffering effects, and there are companies like. lacked ago is one that comes to mind that are now producing really absorbable, transdermal Carnoustie in applications that you'd put on the arms or the legs, and so this could be like a pre. You know suffer fest type of workout stack would be kitone esters, sodium, bicarbonate, microdosing, and then like the topical application of Karna Seen, and that this would be something that for you. You've super competitive athletes out. There would probably serve you well and be kind of like a a tool in your in your back pocket for for lactate buffering Now there's actually one other thing kind of a fun topic I wanted to ask you about Jeff. Fun for some people I suppose, and that would be that you know there. There's this rumble in in the..
"esters " Discussed on Ben Greenfield Fitness
"G., which is the trade name or the or the commercial name for the Keel Mono Ester, which is that Beta hydroxybutyrate butane mono ester? Long Story Short, you had to prove out the human safety. Could you actually feed the stuff that people and does it actually work? There's actually elevate. Ketone levels of effectively and then I would say within the last four or five years with one, a lot of the publications came out for the organic or performance, enhancing aspects of Keaton's and it's been interesting kind of journey being a part of the ecosystem that's working a lot with the scientists for therapeutic use cases for performance enhancement use cases as well as working a lot with. The end users which are professional athletes, military applications as well as folks that are experimenting using this for weight, management, longevity or potential therapeutic use cases, so it's a it's a very fast growing volving field, but it really interesting historical story with how? Everything came together and I think that just the way I see. It is that we're all standing on top of the shoulders of giants, and think Vita cool story where he actually studied under Hans Krebs, who decrypt cycles named after I think that training with metabolism understanding all the intermediates, all the ratios I think informed him of why key tones were interesting from a fuelling perspective. Yeah I know that you actually on your own podcast had an interview with Joseph Belitsky the. Chief Program Manager. DECADE-LONG KITONE ESTRA development as part of this metabolic dominance program that was initiated by Darpa to basically enable superior physical and physiological warfighter performance by controlling energy metabolism on demand. Now that was a fascinating podcast that you did I think a couple years ago, a link to that in the show notes for those of you who who want to hear that, and so the these Kito Nassar's. You've developed them and you guys have hd HBO. Have kind of packers them in a liquid form as a couple, other companies on the market have done you know these liquid kitone doors, which admittedly, and of course I know this isn't news to. You are not considered to be the tastiest supplement that that exists because it is very difficult to get kitone esters which have a little bit of a bitterness to them to actually be palatable. And and you know I. I haven't really found much of a way around them. You can add a little Stevia and you know. Put some coconut water, or you know or Toss Minna smoothie I found the they impart a mild kind of like acidic taste. Even when added to smoothie, but you know for me, it is what it is. I'm so used to testing supplements and formulating supplements and getting random powders sent to my house that I must be. Dumpster into my mouth and taste that I may have killed awesome taste buds, and so for me I. I could be jaded and I have no problem, just just drinking the stuff and continuing on throughout the day. But these these liquid kitone esters. That one would drink when it comes to actual dosage. What's kind of like the gold standard scenario in terms of how the typical person is using these throughout the day and I'm fine. If you break this out into the person who might be using it for you know the executive using it for cognition, the athlete using it performance during events but what's kind of the the general gold standard use case for these. These type of things in terms of of dosage and frequency. Yeah, that's a good question and yeah, the taste is the taste think we've all seen yet. Your conversations as well as folks have written blog posts in the early days eating sort of like the rocket fuel versions of Kita Nassar's. They are not the most pleasant thing, but I like to say it tastes like it works so also with what's been studied. Studied in clinical academic research so typically the dosage is if you want to be very very precise based on body weight, so the clinical gold standards around six hundred milligrams per body weight kilogram, four cute performance use cases, so if that's a seventy kilogram man, hundred fifty four pounds, that's forty two ish grams of Keaton Esther, which is almost two bottles of h on esther product, so you actually need pretty high doses for. For Acute pre-bout pre exercise, use cases, and would the I mean because I, you know I. I began to use ketones back in two thousand, thirteen for Ironman triathlon, and obviously there's a big difference between iron man. Let's say you know whatever a forty five minute murph. So what kind of what kind of level of exercise are we talking about here when you're taking to full bottles of this stuff in terms of volume? Volume, this is primarily geared towards Tour de France athletes so okay very high, Ville, yeah, so so these are pretty serious athlete, so it'd be doing to full bottles of something like kitone Astor's prior to to performance exactly so there's been a number of studies on a number of different applications. Right like you've seen studies where Keaton Salts, either no difference, some Kito Nestor Studies, showing some different some sewing not and sounds like. Like the really the threshold is one body, weight or two, which I think is actually more applicable. You need. Hit a threshold of bed hydroxybutyrate in your blood, and it looks like that number is that you want to at least have two point. Oh, minimal Beta hydroxybutyrate in some of the best performing studies, people are showing blood levels of three to five million mole as going into the most critical parts of their race. Race or competition right, which is very it surprisingly difficult unless you've been fasting or consuming low carbohydrate ketogenic diet for quite some time to achieved that level of mill, at least in my own personal experience without the use of Ketone esters and yet someone who is who is not even fat adapted who you know, be eating seventy to eighty percent carbohydrate can achieve that level acutely upon consumption of these esters and I you. You know for me being relatively fatted Aptidon Kito adapted. If I were to do two bottles, I would be up around seven melamine or easily for for kion values. Yeah, I think that's something that I think is again like I think a lot of people just entering the Kito community are chasing tones and I think you're exactly, right. There's a Lotta adaptation where you get more out that your buys this more efficient. You just never want extra substrate floating around so yeah when you're dumping. Keaton's in your system. I would expect something like that high if you see a lot of. Athletes. We've seen people uptake on so quickly that even for dumping masters in their blood levels correct very very quickly, so it's interesting to see again. Application of the context were some athletes who are very variable train will uptake very very quickly so to answer your initial question for acute use cases with application I would target like the the most professional customers blood HP is the most important thing.
"esters " Discussed on Ben Greenfield Fitness
"That's been my own personal experience. You know like we were chatting about even before we began recording, my wife and boys are out of town for five days and I told my wife when she laughed. I'm like. Don't go grocery shopping. Don't leave anything in the refrigerator. I got some rib eye steaks that I'm going to have a little bit of liber pathway that I make an and some homemade sprouts for dinner every night, and sometimes I'll throw in a little bit of like a organic Pumpkin Mash, and then I'm just planning on jamming through breakfast and lunch on key tones, mcat's and liquid calories in a little bit of bone broth because you know if my wife's. Wife's out of town. I'm go into hyper productive. You Know Work Fourteen to sixteen hours a day and that works very well, I don't I. Don't get hungry at all when I'm doing that. Even and you feel while you're burning view of your own fats, Ben, actually I'm probably bring more of my own fats because I'm I'm once. I added up at the end of the day. Probably consuming fewer calories than I would normally consume, so I would not necessarily throw out the idea of not using, or I will not throw out the idea of using exogenous key tones. If you're trying to lose weight, I think the pros outweigh the cons in that respect. Now you mentioned you know. Know Kitone esters and I know that's the particular flavor or form of key tones that you guys specialize in implementing in in your Hvac. Men, product and Ju-, just briefly, and again I've I've packed this in detail in previous podcast. You don't need to spend too much time on this. Because I'll linked everything. We discussed you. Guys at Ben Greenfield Dot com slash, Woo, W., O. O., but the these kitone esser that using are remarkably different than kitone salts and a I wonder if you can just briefly describe the difference between the two, and then in terms of your product to men how you're using Kito. Nassar's like what form of Ketone Astor's in why it's interesting history and And I've been spent a lot of time talking to the principals, the folks who've been part of this area of research for the last forty fifty years, so to answer the easy part which is what is a Keaton sufferers is what our Akito nesters well, they're really described two classes of exogenous ketones, and then you have things like mcat butane dial where a ketogenic agents or peaking precursors things that readily convert into Beta hydroxybutyrate or Keaton's in your in your system, but aren't actually directly ketones. Okay, so what is the key to insult? It's simply Beta. hydroxybutyrate bound to mineral assault, so a lot of common consults are sodium, magnesium, calcium the pros and cons. There pros relatively cheap relatively. Available the potential cons is that if you actually look at the percentage of salt versus Beta hydroxybutyrate, you're eating a lot of mineral when you're eating Akito insult product, so if you look at the label, oftentimes, you're seeing one hundred two hundred percent your daily. RECOMMENDED VALUE FOR SALT, not necessarily a bad thing, but something that is just part of the molecular construction of a key consult so what are key to investors in general? There's also a whole family of compounds that are ester forms of heat owns what isn't esther. Esther is just a molecule that has a oxygen double bond in between different components, molesters with one Esteban diasters to Ester bonds and there's a whole swath of folks looking at keystone esther, in different types of Keaton Esters, which I think we can. Can Talk a little bit about later. Which is I? Think in the future there'll be a whole family of potential executives. Keaton's just like there's a whole family of carbohydrates from dextrose multidex strength to starches, just like Omega three new make six fats. I think in the future. How you see this industry will evolve, or this notion nutrition evolves is that will be a whole family of exogenous kitone variance with pros and cons, but to talk about what is focused on today and something that we focus on Hvac. is a specific kitone molester that is Beta hydroxybutyrate astaire fight with our one butane doll, which is referenced before a kid agent that readily converts in debate drugs. In your liver. Why does this matter will? It's pretty cool that kitone. Esther basically delivers one hundred percent. Be HP, equivalent versus something like a kitone salt which delivers. Over half of its molecular weight and minerals, there's another Keaton. Esther that Dom Dagestan has done a lot of work around which isn't a CTO asked diaster, and that's a Saito Acetate, which is a derivative form of Beta hydroxybutyrate bound to butane dial into a seato acetates to that so a little bit of different configuration. Okay, now I I was looking at the ATM in Ketone bottle and on there it says Delta G. as the active ingredient in the kitone, esther, A and. Then, it says invented by Oxford and h scientists is part of the Darpa Metabolic dominance program so a lot to detail there, but what is Delta G., and and what is this kitone? Esther? That was an inventive as part of the Dr Program. It's a fascinating story so back in the sixties and Seventies. There was a gentleman in this is a popular. That's been reference a lot lot I think we've talked about this fasting study where they starved Harvard. Divinity students for over a year, and that's he was actually convert conducted by Harvard Medical School professor by name, but George Kale and he was friends with Dr Richard. Vh who I know you will also spoken to and he I would say one of the earliest folks looking at key tones and understanding the metabolic implications of Kito. In, the early nineteen hundreds of nineteen fifties posted a genetic Diet I. Think a lot of people thought of key tones as metabolic waste product for type, one diabetics, but people didn't realize the broader implications as a feel substrate as well as a signaling metabolite so. As people realize Beta hydroxybutyrate could be a useful molecule. There was a lot of research around. Okay, can we do? Key tones in different formulations, so there's lots of on. Intra Venus kitone salts. Other earlier versions of a ketone astor's. But what happened was in early two thousands. There was a Darpa. Program stood up by Dr Joseph Belitsky he actually before his program management spot was actually the chief veterinarian officer for NASA so very interesting guy with interesting career he had. The purview to set up a program to enhance the human factor side of warfighting, so there's a number of different research projects that we're looking at things like quercetin which I think is interesting. Given the COVID recent conversation there were also had things like the the the the cooling glove that came out of Stanford, which showed enhanced recovery was also part of that program, and of course Kito esters also part of that program, so Dr Vh, recruited and brought on board Oxford, professor, who specialist in cardiac metabolism by the name of Prosecution Clark quite work closely with on the commercialization side of Kito esters. And they kicked off a research program this the size and scale up Delta..
"esters " Discussed on Ben Greenfield Fitness
"Professor, Peter Hezbul who's also interesting enough a consultant. Some of the Belgian Tour de France teams started looking at the application dosing protocols for Keaton Esters, so there's been a lot of anecdotal. Hate the we used to work anecdotal, but I will say like the craft of sports performance. I think this is something that you think Ben like know a lot about which is that the practitioners oftentimes are the leading signals or the. With leading signals for academic research, the randomized clinical trials, so one of the observations in some of the early toward Francis was that people felt better, recovery or fresher legs, quote unquote if there were using ketones more for the recovery aspect of versus the pre performance, acute pre-bout use cases, so has bull did a great study that was published in two thousand nine summer right ahead of the two thousand, Nineteen Tour de France, showing that when people mimicked or cyclists mimicked a twitter fence style, a training protocol which is. Around thirteen hours of training a week, which had to workouts per day over that week period and using kitten extras plus protein and carbohydrate versus a calorie, equivalent protein and carbohydrate drink alone after three week training period of that regimen folks that had the Keaton Esther plus intervention had a fifteen percent increase in overall trading volume, and at the last thirty minute time trial a five percent. PERCENT, increase in performance, so it is, this is one of those interesting study points where the anecdote or the practitioners who were actual athletes experimenting pushing. What was possible, actually informed what the academics did in the clinic. That's an interesting point. I think there's a lot of speculation of why key tones would do this and one of the interesting mechanisms that I really liked from that study. Or was informed by previous Peter. Husbands study was that key tones plus protein and carbohydrate actually up regulates Amtrak one so m tour, which is kind of the muscle synthesis protein synthesis pathway that has been interesting in some of the jets third up regulating anabolic pathway exactly exactly. So I think that's one of the interesting things with tones where you can talk about them. In terms of cannibalism or anti catabolism, which does make sense from evolutionary perspective, because when would the ancestral human go into ketosis while they would go into? Starvation, state so having anti-catholic facts is consistent from evolutionary perspective. Okay, got it now now. That's interesting because you know in the past. What one of the benefits that has been highlighted in terms of being a ketogenic state is the blockage of 'EM TOR via the increased activity of amp K, meaning that when amp K. is is increased, then it would be a signal that that that ATP stores would be in a state of depletion and you'd see. See an inhibition of things like uncontrolled cell, growth, proliferation or oxidative stress, therefore, a lot of people would associate ketosis with a non anabolic state. If it blocks m torso, what was different in this in this study or or what's occurring from a pathway standpoint that this would actually activate Amtrak, because we've been studies on pubmed that say that Akita Ketogenic Diet would inhibit tour. That's exactly the right question. I think that's something that I've been really focused on which is. There's application specific and context specific use cases for something that is like a macro nutrient, so the difference here is that, yes, in an ancestral consistent state of a ketogenic diet or fasting, you will not have the presence of carbohydrate in protein so when there are key tones through a ketogenic diet, it is exactly correct that you would expect to see 'em tour being down regulated and amp k being a down regulated as well because there's kind of that lower available energy substrates from glycolysis, and then you see up regulation of. Life policies and fat mobilization, but the difference with exogenous cue tones. Is that now you can have exogenous. Plus external subjects approaching carbohydrate, that's where it's interesting piece of research or a new field where when you have ketone stacked with availability of protein and carbohydrate. That's where you see the divergence between endogenous. Chitose and EXOTI- ketosis. I think that's a under studied area or area that will be a major field of study I would say in the next to five ten years. Okay, so so to clarify for folks. Then what you're saying is that if you were interested in using a ketogenic state for recovery? What you would actually want to do is have adequate nutrient ability with adequate calorie intake, and arguably even you know a enough carbohydrate to allow for liver muscle collection levels to be full, and you would achieve that via feeding as you normally would, but then including ketone. And that would induce an anabolic pathway that would be over, and above what you'd see in the absence of the same approach without kitone esters, however, if you wanted to instead trigger pathways of Autophagy, enhanced vetting or decrease 'em tour been what you would do is use a similar approach, but instead use nutritional toasts and or use of kitone astor's, but in the presence of a lower amount of carbohydrate and overall calorie availability, so there's kind. kind of like two different ways that you could use ketosis hundred percent I think it's a nice summary. Okay and I think that opens up an interesting many topic around why cholera restriction works in is triggered. I think the consensus is that Kito or the key tone Beta hydroxy beater itself May, at least partially mediate that response so I think there's an open research. Question Does Beta hydroxybutyrate itself be the signaling molecule that triggers. Inhibition Fox three somebody's longevity pathways, or is it the calorie restriction itself? That's an open field of study so basically the way this study. This is that if you just have an executive Keaton without calorie restriction. How much of the calorie restriction benefits do you see? That has been questioned? Okay, got it so we we know though thus far that especially based on this recent study and cyclists that if you throw ketone esters into a recovery fueling based equation, you're going to see enhanced recovery up regulation. M Tour an activation of anabolic pathways. Pathways over, and above what you'd see in the in the absence, keystone esters correct. Okay, got it now. kind of backpedaling just a little bit here. Let's talk about the difference between what's happening in the body, if in and we kind of talked about this, but I like a little bit more thorough explanation if someone were to achieve Kito says via what might be called. You know endogenous ketosis. You know carbohydrate restriction, Calorie, restriction fasting, etc.. Verses entering into Ketosis simply via the use of what many people call cheating or the USA. Ketones like what's the difference there? As far as pros versus cons of each all star, what's happening physiologically so indulgence Kito service necessarily, there's some sort of carbohydrate restriction which could be calorie, restricted or not right. kitching diet is not calorie restricted, but there is definitely a carbohydrate restriction. So what happens there? Is that the brain senses? Brain, but US other tissues also care about energy sensitivity. There's it starts detecting away PK because there's a lack of glucose what happens. The body responds by increasing like policies, increasing fat mobilization, and the interesting thing about the brain is is that there's a blood brain barrier that prevents. Fat Directly, entering the brain to provide fuel or subject for neurons, so what do animals in a number of animals have this metabolism metabolic pathway of what happens all? They evolved this pathway Kita Genesis Chitose where it converts fat into Ketone, bodies and ketone bodies or small molecules like do cross the blood brain barrier. So what's what's The T.? L. Dr the summary. They're usually in the dodgers. You see an increase in free fatty acids because he mobilized more fat, you see.
"esters " Discussed on Ben Greenfield Fitness
"Fifth Murph in a row realized that you're doing pretty anaerobic movements right like doing a bunch. pull ups push ups and a mile. Run is not a big endurance run. I felt like I needed additional carbohydrates right there. There's some definite glick throughput, and even more when you're doing it for forty five days sequentially, or you're looking at some some hefty needs for for liver muscle glycogen replication. If you if you actually want to not be out there for two hours. One hundred percent, so I started adding carbohydrates pre and post, and then I would have either key astor's or other exonerates key tones like mcat, oil, powder, or something along those lines to. Increase kind of the key tone plus protein carbohydrate recovery benefits that some of the some of the more recent literature has shown to be effective, so I was mainly using key a key topic approach for the recovery side rather than performance side because one. This was not for an acute time. Maximal effort this was. A marathon if you will right right and by the way, the simultaneous elevation of blood, Ketones and blood glucose is something I experimented with a few times when I was doing obstacle course racing, and it is like rocket fuel, you know it is admittedly from an evolutionary ancestoral standpoint, probably not a physiologic condition and I. Don't know if you agree with me on this that. Humans would have frequently experienced elevated levels of key tones which normally would be listed by carbohydrate, restriction and physical activity and fasting. But instead you know are brought on by the ingestion of something like Kito. ESTERS or kitone salts, which are then combined in the case of the way that I was doing it with either a dextrose based fuel or a Maltodextrin fructose based fuel. You've got incredible amount of glucose uptake on the high glycemic index of the dextrose or the multiple glucose transporters being used by the combination of Maltodextrin fructose. You essentially are kind of like hyperglycemia and hyper key todic, and it's like rocket fuel for for exercising, but I would argue that that is a that it's. From an ancestral standpoint, a physiological norm as far as the place for the human body to be in that is correct, it is not physiologically normal or typical state, and that's because if you think about how why kisses exists, it's really a sort of a backup metabolic process in carbohydrate, restricted states so in a typical metabolism. You either have high availability of Glucose. Glucose therefore not carbohydrate restriction, so there's a lack of need for up regulated like policies and up regulated Genesis so the interesting thing with keystone ezzor exotic locations in general. Is it really was conceptualized as a research tool, and I think a lot of discussion about kigen nights or Kito? SIS has always been conflicted around a high fat, low carb Diet and. With exotics Ketones, you can finally have a tool that does not require a high fat low carb Diet to induce Ketosis so I think one of the refrains that you hear different researchers talk about is that key tunes can be thought of as a fourth macronutrients, so as opposed to looking at key tones as it endpoint to reach to or Akita's endpoint to reach to one can now start thinking about key tones as almost equivalent. Equivalent to carbohydrate or protein or mcat or fat, as a starting point in terms of nutrition and input into metabolism, so I think that's where the paradigm shift is interesting from a research perspective, and exactly in terms of an accident perspective I, think what you're referencing has been a very interesting last couple of years for there's a lot of uses in the top levels of sport and military where you just unlock this novel physiological state. State that does not occur in nature right right exactly now I wanna I wanNA quickly. Visit something that you mentions when you were talking about your forty five days of Murph and then by the way for those of you, listening in who might be somewhat knew to key tones in kitone esters and in key in general. We're not going to spend a lot of time on Ketosis one one, but I will in the show. Show notes put links to a lot of previous podcasts. I've done kind of walking you through the basics of Ketosis, and so if you want that as as a foundation, just go to Ben. Greenfield fitness dot com slash Wu as in W. Ho which is Jeff's last name and Ben Green Dot, com slash Wu all linked to other podcasts that I've done on. Kito says if you need to kind of get a refresher. You know folks like Jason. Fong in Jimmy, Moore and Dominic Diego Dino and host of other people have interviewed on the basics of. because we're really going to delve into some more specialty areas on today's show, but you mentioned Jeffrey the use of kitone. ESTERS or or Ketosis in general for recovery, and some of the new literature around that it's not really topic I've talked about much versus say performance or cognition, so what role do keystones tones play when it comes to recovery? I would say that a lot of the early research, but early is in sort of mid two thousand tons of two thousand sixteen to eighteen has been focused on acute performance benefit so using ketones, esters, or exotic dunes as a pre fuel do a time trial. Usually a lot of these studies done on cyclists or runners, because these are very simple, quantitative sports rights much easier to measure the performance of someone on a bike versus someone playing soccer for his technique strategy involved in winning in two, thousand, eighteen, thousand, nine, hundred twenty. Research Group based in Belgium. Kayla von by a.
"esters " Discussed on The Peter Attia Drive
"Maybe explain for people. What the differences between assault and esther? So we'll leave Procedo acetate out of that for a moment yet but if you talk about Beta hydroxybutyrate but you can have this. Us state salt too. So I can mention that. I didn't know that I thought it was only a diaster. So that's definitely want to hear about that and so on the beach front. People are sort of inundated with kitone salts ketones esters and then a whole bunch of complete like weird stuff like raspberry key tons and stuff but yeah. Let's just leave the nonsense off the table? Yeah but if you talk about comparing Kitone Abi. Hp HP salt with the chemical difference. Yes so a salt is just an iconic bond rate between the keystone molecule Beta hydroxybutyrate. A monovalent or a divestment cat eye on or an alkaline amino acid like arginine citrulline history lycene so you can literally I honestly Bond Beta hydroxybutyrate to a number of different things? The easiest thing to do is to bond with sodium potassium calcium and magnesium or calcium and magnesium have two positive charges. You could put to. Hp's on them on the advantage. Sort of an advantage a disadvantage. I guess with magnesium be HP which is actually very bioavailable magnesium. I measured my magnesium after taking it went quite quite high disadvantages that your Gi tolerability to something like magnesium Beta hydroxybutyrate may be only somewhere between one to three grams three grams. Max Produce. One Gram three times a day. At least for me had no issues. I could probably tolerate two or three grams per day. So it's Nice I mean it's something that's contributing but ideally what you WanNa do with Akito. Salt is because all. It has a stigma. I call them kitone. Electrolyte formulations is to spread. The Beta out across monovalent. Divan like Canada. And they're the four that have the most utility and then an Ester of course is a valence bond. Not An iconic bond right. Yeah so you can take one three butane dial and you could create a Mono Ester with Beta hydroxybutyrate ray and just add it to a trans extra vacation reaction and combine that Beta hydroxybutyrate. Two one three butane dial or a CTO ACETATE. You can combine two with one three or you can take glycerine so with glacier all you can come up with a trustor of glycerine which we have creating a triglycerides that is instead of three fatty acids. Yeah but three. Hp's it's pretty cool molecule. Yeah so we have some experience using anything that so. I told a story like many many years ago. Four or five years ago on Tim. Ferriss podcast about how I drink as jet fuel and almost thought it was going to go blind. Of course what I may have were may or may not have omitted from that story. Was that you gave it to me. The key tones today taste a heck of a lot better than that earlier. Jen stuff even when I told you that I just took the fifty m L. Vile you sent and chugged it in one sitting. Even you were sort of horrified. You're like way you didn't read the note I wrote you explaining how do deluded and mix it talked about. Assuredly talked about your very enthusiastic about getting started. Yeah I couldn't resist. I was too. That's stuff's unbearably bad. So what I mean whereas the keystone salts actually don't taste bad they're awesome. Yeah Yeah so. Why does the astor is there? An obvious reason from an olfactory slash taste perspective. Why they are so staggeringly horrible. Yeah they were. I mean I'm told they're better today. Yeah I would say the ketogenic potency is inversely proportional to taste so it just seems like you know the more the more potent these compounds get even the triumph Esther Beta hydroxybutyrate with a pretty nasty stuff. Meaning that Glycerine triglycerides that. Yeah it's a great molecule. I mean it has like loss of tremendous utility will making a keystone esther with three butane. I'll is really cool. Because the one three butane dial substrate broken down. Yeah so that goes into another question the whole an anti MIRA so if you use the are Beta hydroxybutyrate with the are one three detained. I'll then you can really get kitone levels up pretty high and that would be sort of the Delta G. or the human. You Know Kito Nestor. That's out there. Hope you enjoyed. Today's special bonus. Episode of the quality new episodes of the qualities released Tuesday through Friday each week and are published exclusively on.
Chicago Woman Is Second Patient in U.S. With Wuhan Coronavirus - What is the Impact on Markets?
"Second case of the Corona virus was confirmed today in Chicago. It involves a woman in her sixties who had travelled to the Chinese city of Wuhan where the outbreak began. Chicago's health. Commissioner says. The woman has been isolated in a hospital and is doing doing well. Meanwhile the virus continues to spread in China the state run broadcaster now reports twenty six deaths and at least eight hundred eighty one confirmed cases cases authorities or canceling large public gatherings and locking down cities. The outbreak is also rattling markets here in the US and abroad. Some are predicting it could have an even bigger economic impact than the two thousand three SARS outbreak joining me now with more on this Wall Street Journal markets reporter Gudgeon Banerjee Gene so gun. It's still relatively early and to this outbreak but how our economy is feeling about the potential impact of the corona virus on China's economy. Especially especially that it's hitting during the Lunar New Year celebrations sure so investors and economists are closely watching how this mysterious pneumonia causing virus will impact act the economy and even stock markets. It is too soon to tell but there is a worry that the sickness could spread and hurt areas like transportation shopping business meetings and therefore ended up crimping economic growth for example this week luxury retailers travel companies and casino stocks were hit by news of the virus what about consumer consumer spending and the impact there especially as we head into the Lunar New Year holiday which formerly begins today on Friday. Does this outbreak complicate any other headwinds ends. We've been seeing in the Chinese economy. That's a really good question. The timing of this outbreak is important with China. Entering one of its busiest travel periods of the year heading into the Lunar New Year holiday the Chinese consumer is really important to the global economy and the Lunar New Year is the busiest travel season and the world's largest annual human migration Chretien so millions of Chinese travelers are estimated to visit families or go on vacation during the holiday but even before all of this. The outlook for economic growth in China China was a little bit cloudy. Chinese officials recently said the country capped off twenty nine thousand nine with an official economic growth of six point one percent so that was within the government's target but also the lowest level in nearly three decades we've also been reporting that. US businesses and just reminder listeners. There now now to confirmed cases here in the US US businesses. Operating in China are taking steps to mitigate the impact and you found. They're also facing some questions from consumers and investors esters exactly so the Chinese consumer is really important to the global economy and Walt Disney recently said that it would temporarily close its park in Shanghai. Starting Saturday and McDonald's said that it closed doors and parts of China and some cities that had suspended public transportation. So China is one of McDonald's largest foreign markets. And I've been tracking corporate earnings as they trickle in this week and just yesterday proctor and gamble executives said that they're monitoring the virus and they also said that it could affect consumer confidence in large parts of the market because it can affect travel which also affects proctor and gamble's business us now. This particular outbreak of the corona virus is also drawing comparisons to the SARS outbreak even though it's currently believed to be a milder illness but SARS did to have a substantial impact on the Chinese economy right. The SARS outbreak did weigh on China's economy at the time and again. It's still a little bit tough to tell what impact this virus this will have on the Chinese economy or the world economy but previous outbreaks. Like those of SARS or Ebola in two thousand fourteen suggests that markets tend to see short-term turbulence but can bounce back pretty quickly for example stock indexes in mainland China and Hong Kong saw double digit percentage drops after SARS before bouncing back all right Wall Street Journal reporter Engine Banerjee joining me here in our studio in New York. Thank you so much. Thank you for having me.
Tips for a Smooth Cruise Embarkation Day
"Make him vocation stress free by arriving at the cruise port. The day before. That means that if there's any hiccups with travel flights trains. Whatever you're using to get there you have plenty of time to resolve it flying hanging on the day of the cruise? It can be really really risky so I like many experience cruises always aim to go the day before it gives you a chance to settle in solder order knee issues. You've got and if there are any hiccups some travel you can resolve them so one of the most important things to do is to build your budget and plans to get to the port the day before my second big tip is prearranged and book as much as you possibly can online before the crews and there's a couple things to really focus on first of all if you're flying into during the cruise in Canada or the United States and you from outside there. Make sure that you've got all the esters the same if you're travelling to any countries where you might need these. Make sure that they're all done and sorted. Secondly you'll find most cruise lines ask you to check in online at your credit card for details so when you arrive at the port already have like an e ticket print it out and you can get through the check in with just that and your passport and get through the ship really quickly. Also make sure that you've pre-booked things with that's excursions drinks packages especially dining or any other things that you can pre book online search search. You know that everything's Sorta so you don't have to get on the ship rush around and Molly trion bookshop excursions before they go get your specialty dining times that you want or whatever it is so basically do that before so you have time to think about it. You can look at the deals in the office and not locked down. Also make sure that you've downloaded the cruise line APP if they have one because you find one show on board you might find that more difficult to download so download it when you have good Wifi or data
Trump considers dramatic escalation of trade war, stopping Chinese firms from US listings
"We begin today in the realm of what if what if the trade war gets worse what if in addition to tariffs and the currency ward that's been threatened. What if the trump administration puts limits on the actual all movement of Money Bloomberg first reported that the White House has been thinking about D. listening Chinese companies from American stock exchanges and putting limits on how Americans can invest invest over there. We should say at this point that the Treasury Department says there is no plan to block Chinese companies from listing on US exchanges for now but as marketplace's places tracey Samuelson reports to get going this whole idea is a bit of a tone change restricting investments would open a big new front in the trade tapeworm says Dan Rosen with the Rhodium group as big as the A to a trade is between the United States and China the financial interaction. It is a much much larger number about four million dollars a flows in both directions according to Rhodium estimates Lee Miller is CEO of china-based book a data and analytics six firm. You've got over a trillion dollars market cap of Chinese companies. They're on US exchanges. You've got enormous opportunities to invest in in in Chinese financial and capital markets going forward what would essentially do is it would shut off a good portion of the investment universe from US investors esters. Miller says US regulators don't have access to the same financial information about Chinese firms listed on U. S. exchanges as they do American ones so strengthening those requirements me aiming sense. If you're Walmart you are subject to a certain set of standards. If you are Alibaba and you're behind the Chinese firewall here then you're able to you push back against this oversight and it's it's becoming a bigger problem. Rosen with Rhodium group says imposing investment restrictions isn't unusual against adversaries. The series like Iran North Korea Cuba. What's very abnormal here is that we haven't at all as a nation or even as a government decided that that's how we you want to consider the People's Republic of China. He says historically. US policy has tended to treat China as more of an economic opportunity than a threat. I'm tracey Samuelson for marketplace
"esters " Discussed on NBC's Songland Podcast
"Hi I'm Audrey Morrissey. I am the Creator and show runner of Song Land and today. We have a really special edition. I'm going to be joined by Ester Dean. The incredible Spitfire of a woman. She is and she and I will be discussing how this show came together. We'll be talking about a lot of the amazing things that happened off. Camera that people who enjoy the show have not had a chance to see. I am the showrunner of the voice and have been since start. I had a lot of experience with how music connects to people on TV. My experience on the voice is all about finding big broad songs. That people know they can enjoy. They can connect to but I realized I was only showing a stage execution of somebody's art. I was never in rooms with these artists as they considered their material or they were writing their material or they were thinking about new songs and getting pitch songs so I thought wow the songwriters and the songs there's nothing without them and it's everything and people know so little about how songs are made so my partner had a meeting with Dave Stewart and he came back and said you really need to meet Dave Stewart. He has an incredible show about songwriters and songwriting so realizing that is spent so much of my time thinking about songs with these coaches. I realized this is a genius idea. And there's a real need for it because most people I know love music. It's part of their daily lives yet. They know so little about how songs are made and I thought we need to do this but we had to come up with a format. That would be interesting and also I do have concerns. Are there a ton of great songwriters? All over the place. I mean it seems like a really difficult thing to do but talking to Dave. It was as if they're just dropping from the sky. You just bump into them so one of the first things we did is NBC. Gave us a little money to do a casting to see it. We had the first meeting of what they found. It was unreal. The songs were incredible. But what was most exciting? Is that the people themselves were such characters and I realized. Wow this has such a different feeling than a typical voice casting and it's really because these are people who have something to say they're writers. It was incredible so that really gave us a lot of confidence that there was a real rich pool of talent to pull from but then the next thing that was really difficult to navigate. We needed an organizing principle around the show and we had this idea to. Have you know a recording artists? Come on every episode to anchor the show looking for a song and then we had to. Of course come up with our panel. Who is going to be on the show? And it was Dave who said Ester Dean you have to have Ester Dean. I'll never forget I. I met Esther Dave had a studio at Hollywood and vine had an office there and esters here with us. Yes I am but he invited me to meet you and I think he told me he. D M Ju like on twitter or something I always wrote songs for interscope for Jimmy Ivine. That's how you know that was my platform and I was a signed to interscope. When I met Dave in I was I was always writing. And Jimmy Ivine love for his writers producers to get to know the industry so I've always been told to be exclusive. But he would take me around to meet the people who he felt. Would matter to me and my life and Dave Stewart is one of those guys Jimmy fell. It was good for me to meet Dave Stewart. So then later in life he did me. And he's I gotta show and you're going to be on an ask. Hey whatever you doing. I'm down so I didn't even question it. I said. That's Dave Stewart. He wants to do some. I'll do it when it's time amazing. It was amazing. It was amazing so I met this fireball and it was like done and done I think. At that time I had already been talking with Ryan. Tetter about the show. Adam Levine is a producer on the show and I have been asking him while at the voice. Look what do you think about this? Show who do you think should be on the panel so he was really instrumental in helping me identify people? That would be good because he's in these rooms with these people all the time so I have been talking with Ryan for Awhile. I now had superstar esther very important to me to have a female on the panel and I needed somebody in country. That was kind of the last piece. There is no way I was going to do a show about songwriting without Nashville represented and all roads pointed to Shane. So they all sign on week before the pilot. I have them out to my office. We have a little studio there and we wanted to see what would happen. That was the other big thing with this. Show trying to explain to executives and people what would happen. That would be a common question will what am I going to be watching? What will people actually say because unlike the voice you're not trying to get them on a team or whatever and you say astor going to say when she hears a Song? I have no idea but she. I'm sure she's going to have something to say. So that's what we're really testing to make sure we knew what would happen and for them to get a feel for each other. So that's really how it came.
"esters " Discussed on NBC's Songland Podcast
"Hi I'm Audrey, Morrissey I am the Creator and show runner of Song Land and today. We have a really special edition. I'm going to be joined by Ester Dean. The incredible Spitfire of a woman she is and she and I will be discussing how this show came together. We'll be talking about a lot of the amazing things that happened off camera that people who enjoy the show have not had a chance to see. I am the showrunner of the voice and have been since START I had a lot of experience with how music connects to people on TV. My experience on the voice is all about finding. Big broad songs that people know they can enjoy. They can connect to, but I realized I was only. Showing a stage execution of somebody's art I was never in rooms with these artists as they considered their material, or they were writing their material, or they were thinking about new songs and getting pitch songs, so I thought. Wow, the songwriters and the songs. There's nothing without them, and it's everything and people know so little about how songs are made. So my partner had a meeting with Dave Stewart and he came back and said you really need to meet Dave Stewart. He has an incredible show about songwriters and songwriting. So realizing that is spent so much of my time thinking about songs with these coaches I realized. This is a genius idea and there's a real need for it because. Most people I know love music. It's part of their daily lives yet. They know so little about how songs are made. And I thought we need to do this, but. We had to come up with a format. That would be interesting. And also I do have concerns. Are there a ton of great songwriters all over the place? I mean it seems like a really difficult thing to do, but talking to Dave. It was as if they're just dropping from the sky. You just bump into them. So one of the first things we did is NBC gave us a little money to do a casting to see it. We had the first meeting of what they found. It was unreal. The songs were incredible, but what was most exciting. Is that the people themselves were such characters and I realized? Wow, this has such a different feeling than a typical voice casting, and it's really because these are people who have something to say. They're writers. It was incredible, so that really gave us a lot of confidence that there was a real rich pool of talent to pull from. But then the next thing that was really difficult to navigate. We needed an organizing principle around the show. And We had this idea to have you know a recording? Artists come on every episode to anchor the show looking for a song, and then we had to of course come up with our panel. Who is going to be on the show? And it was Dave who said Ester, Dean, you have to have Ester Dean. I'll never forget I. I met Esther Dave had a studio at Hollywood and vine had an office there. And esters here with us, yes, I am, but he invited me to meet you and I think he told me he. D M, Ju, like on twitter or something I. Always wrote songs for interscope for Jimmy Ivine. That's how you know. That was my platform and I was a signed to interscope when I met Dave in I was. I was always righty and Jimmy. Ivine love for his writers producers to get to know the industry, so I've always been told to be exclusive, but he would take me around to meet the people who he felt would matter to me and my life and Dave. Stewart is one of those guys. Jimmy fell. It was good for me to meet Dave Stewart so then later in life. He did me and he's I. GotTa Show, and you're going to be on an ask. Hey, whatever you doing. I'm down, so I didn't even question it I said. That's Dave, stewart he wants to do. Some I'll do it when it's time. Amazing it was amazing. It was amazing so I met this fireball, and it was like done and done. I think at that time I had already been talking with Ryan. Tetter, about the show Adam Levine is a producer on the show and I have been asking him while at the voice. Look, what do you think about this show? Who Do you think should be on the panel? So he was really instrumental in helping me identify people that would be good because he's in these rooms with these people all the time. So. I have been talking with Ryan for Awhile. I now had superstar Esther. Very important to me to have a female on the panel and I needed somebody in country. That was kind of the last piece. There is no way I was going to do a show about songwriting without Nashville represented. And all roads pointed to Shane so. They all sign on week before the pilot. I have them out to my office. We have a little studio there and we wanted to see what would happen. That was the other big thing with this show trying to explain to. Executives and people what would happen. That would be a common question. Will what am I going to be watching? What will people actually say because unlike the voice? You're not trying to get them on a team or whatever and. You say. What is astor going to say when she hears a song? I have no idea but she I'm sure she's going to have something to say so. That's what we're really testing to make sure. We knew what would happen and for them to get a feel for each other. So! That's really how it came.
Most scientific studies only use male subjects
"Welcome science for the people. I'm i'm bethany brookshire science writer at science news and society for science and the public a good chunk of what we know about the human body and brain comes through studying animals such as mice and rats scientists study animals to understand issues like anxiety drug addiction depression cancer much much more. There are of course questions surrounding miss people might worry about animal testing how good these animal models really are at modeling the human condition. Those are important questions but here's another one. What if i told you that most of those studies have been conducted only in male animals. Wouldn't you wonder why oddly many scientists haven't wondered why they just assumed you study males because females were variable. They had these things these hormones so so weird but who said that who said that males were the default in animal studies and why here to talk about it. Is rebecca shanansky a neuroscientist at northeastern university in boston rebecca. Thank you so much for making time for us. I'm very happy to be here in fields like neuroscience zero science as i've just mentioned male animals tend to be studied more often than female animals. Do we know how much more often what are the percentages of studies that only study males or <unk> studies that study both sexes. It's about a five to one and radio <hes> at this point where with males being the preferred sex to study so that would be about eighty percent of studies are for males only correct yet and the issue that scientists frequently site for studying. These male animals is that females are seen to be more variable. What does that mean and why is that so the reason for that is based on the on the rodent estrus cycle which started like an abbreviated menstrual cycle for female a female roads and so the idea idea here is that every couple of days hormone levels are high and then they get low again and so if you're testing group of female animals you <hes> <hes> you might have some of your animals with high levels of estrogen and some of your animals low levels of estrogen and that might cause your beta to <hes> to be different depending on which phase of the extra cycle the animals were in and so the perception and based on that information is that you shouldn't study females emails because it's going to be very complicated <hes> in your data whereas males don't have a cycle and so their data will be essentially cleaner and you mentioned engine. There's these high levels of things like estrogen do do rodents have progesterone as well. Do they have that so they have progesterone too so per gesture on <hes> just after the estrogen week <hes> an and both are low after that. There's this concern that it will introduce this this variability in the data. How much variation is there over this cycle. I mean is it like two times as much estrogen three you times fifth light. It's more like four or five times higher so it is a lot higher. It's a lot higher <hes> but but the the premise that that is going to be guaranteed to affect your data is one that is not founded in reality i was i was going to ask i mean do we know what the behavioral effects of these cyclic hormonal variations in and females are so certainly people who have you know been brave enough to study females <hes> have found that the ester cycle can chan affect <hes> behavioral outcomes but it doesn't happen all the time and the magnitude is certainly nothing like the magnitude of <hes> <hes> variability in hormones dot right so if whatever your behavioral outcome measure is it's not going to be five times greater in animals that have high levels master. Jan versus animals have low levels of estrogen. <hes> it you know you can sometimes pull out significant statistically significant differences but <hes> it's not as wildly wildly crazy as you might imagine given the amount of <hes> you know sort of magnitude of change and hormone levels and these
"esters " Discussed on Smash Boom Best
"In michael jeffrey be so on esters in peter egland brandy is there anyone you wanna think today yes i'd like to thank my mom alice brown and my cat cookie lion and what about you katie i'd like to thank my boyfriend match you go to that shot up at my dog that's a shame good an de new yorker writer kathryn schultz who wrote a great article and instability in how about you rhonette any special shout outs yeah i'd like to think there were general science talent search dia awesome program that i was able to find out about this really cool podcast awesome end before we go let's call up a limb and malcolm their listeners who suggested the ten vs pencil debate i think pailin no initiation penciled wins this is a generational you have to worry about running out of his brothers on either side of the debate who do you think would win if you have an idea effort ethic debate battle had to smash boom dot org and tell us all about it that's it for this episode of smash boom best will be back soon with another debate battle pizza invisible man in a magical a pattern and the magic man.
"esters " Discussed on THEMOVE
"To just, you know, keep doing this, and I haven't talked to you, too, about its esters pry talked y'all about that offline but I would love to I think for the tour as well this, this element of, of trying to preview what's going to happen in those stages. What we'll figure that out? But it's been you know as we program out more and more of the move and build this audience bigger and bigger. It's just, you know, I mean for me, I'm I'm really glad you'll let me yell at me jump in every now and again, but I'm just humbled that, that people continue to support and I and I think I speak for Johann. I think, you know, everybody knows the story. I don't need to I need to remind anybody and Johan Bruyneel is not an evil person. He's an amazing man and he's the best that ever was at his at his disciplined. And so it's been an honor having him sit here and and, and express his genius to us. And I and that, that came through loud and clear. We heard it and read it and all the comments, and it's been. It's been a real treat Johan any final thoughts reflecting on the last three weeks. Yeah. Well, I mean first of all, I really wanna thank both of you end the whole team behind the move to, to have me on the show. It was a first for me. And I've really enjoyed it a lot more than I expected and. I mean it was it was really it was really good for me to for myself, because, you know, I have a have kind of kept a low profile for a long time and. Is the first time that I kind of came out and gave my opinion again. And I, I discovered that, you know, I I'm still in love with the sport of cycling very much. I've enjoyed watching every stage and analyze it then, and I really I mean, I took pleasure from from from doing this, and as land says, you know, we, we should probably talk about how we can build this further, and how I can contribute to if it's the tour of welter or other or new new pieces of content but I really enjoyed it. I, I really liked and, you know, read all the comments loud, a lot of positive comments, and really nice feedback and also want to thank all the all the listeners for, for tuning in, and then following so closely so yeah, I I'm up for. I'm up for a repeat. Definitely. Yeah. Great. Well, J B. What do we have thanks for saying that, you know what would? But what do we have? What did we have on tap? We've got the tour coming up just for you. Obviously that, that, that listenership viewership is, is large, but we've just a little preview and I've snuck some stuff on Instagram and Instagram's stories but we're going to completely revamp, the we do store, some of the some of the old faithfuls in the bestsellers will will remain, but all new designs on tees and hats, and then some fun little new things we got we got a notepad. We got pulp point pin. We got a coffee mug. We got I it's just, you know, keep an eye out for that. We'll go live with that, obviously, sooner than later, and then and then on the membership side, which I don't know if we all remember not a great membership program last year, that too will be amped up and beefed up. And I guess last thing, I'll say is, it's gonna look a little different because we're we're, we're out of the we're out of the airstream and into. You know what it's gonna look like a legit studio. We got we got a studio desk built. We got you know, it's, it's we're going straight sportscenter on this shit. And, and we'll see. It'll be interesting. J B. I don't know. I, I, I wonder what the how the dynamic will change from just sort of sitting around casually in mobile or an RV versus sitting at a desk. So hopefully, we can we can keep the trash talking at a maximum. Well, the energy, the same in Georgia is going to be there for the entire tour. Correct. Yeah..
Decanting Wine Changes Its Chemistry
"The wind Kanter is fairly standard vessel found in many glassware collections. But it's also a rather mysterious object that inspires questions about how to use it and what function decanting actually serves. So what does it mean to decant wine simply put? Simply put decanting involved pouring wine or any liquid from one container into the Decatur while some decanting serves more to ornament presentation of dining experience, the canting certain wines has an evident effect on their aroma and drink ability as wine ages, it's our Ganic molecules grow larger through polymerisation, which reduces its stringency and makes the wine softer less Truckee. But over time a wine may deposit, crystal tar, traits and pigmented organic substances called tannin's that collect sediment at the bottom of a bottle. Do gathering separates out though, sediments that build up. This is usually only required for high end wines with vintage date over ten years to canton can also help to release volatile compounds in wine that mask it subtle flavors. These volatile 's are a combination of organic compounds that at aromas such as fruit oak, tars esters or aldehydes deterring young one group rates oxygen. Helps to evaporate any harsh volatile xlt. Now, the winds tastes and smells will be more discernible than the astringent alcohol red wines acquire their chemical characteristics because they're held in relatively oxygen free environments during aging in bottles white wines. However, don't benefit from decanting because they aren't aged bottles long before serving so feel free to skip decanting your Chardonnay, but if Malbak is on the menu bring out the cancer for the sake of showmanship and flavor whose moment of science comes from Indiana University. I'm Don glassed. I'm Yale Cassandra.
Bankruptcy Filings Indicate Times Are Tough For Many U.S. Farmers
"This message comes from NPR sponsor snowflake. The only data warehouse built for the cloud unlock. Deep data insights with the instantly scalable, cloud built data warehouse. Start your journey towards data driven decision. Making it snowflake dot com slash NPR. Bankruptcy for farms in the mid west rose sharply last year. And it's not just one thing that is pushing farmers over the edge. Esther Hoenig of harvest public media reports that many of those farmers have been hit by a trifecta of trade disputes, continuing low crop prices and now extensive flooding. Corn is pouring into a semi trailer. Ben Steffens farm in southeast Nebraska. Corn out, and we will call it to atchison Kansas. That's about eighty miles one way staffing calls this past winter. Brutal on this frigid day in March most farmers couldn't clear their snow packed roads. He could which meant he got a bit more money for his corn. We're in a situation where we're we're counting nickels and pennies on every transaction and we're trying to capture every every penny weekend over the last few years. Farm income has dropped by half since high point in two thousand thirteen when you spent five years of your life pouring, your energy into a business and you're worse off today than five years ago. It feels like a crisis if dismal situation for many of America's commodity farmers, and it sparked concern that the agony tree may be on the cusp of a major downturn like in the nineteen eighties. When scores of farms went out of business. One indicator could be the number of chapter twelve filings, a special bankruptcy. Code for family farms last year. It reached nearly five hundred that I'm looking at right here suggested. Actually, we had higher. Bankruptcy rates in twenty ten in twenty eleven David Whitmore is an economist with the website agricultural economic insights. He says well overall, the farm bankruptcy rates look relatively normal to get the whole story. You have to look at all the numbers bureau wanted took into my phone with the dash the metrics that we all talk about our trade being the wrong way, metrics lake farm income would says trade disputes have hurt markets and slashed exports of major crops like soybeans and Nathan Kauffman of the Federal Reserve Bank of Kansas City says that means excess grain is piling up. And it's pulling prices down to at or below the break, even Mark whatever may or may not happen with trade policy. I think those supplies are likely to continue to weigh on commodity prices for this receivable future. Kaufman is watching to see if this drags down. Other key financial indicators like loan repayment rates. Land values at the moment. He says, it doesn't look great. But it certainly has not gone to the point where I think that that we would call it. The kind of crisis that we saw playing out in the nineteen eighties. But tell that to the farmers in states like Nebraska and Iowa were recent floods killed livestock and drowned hundreds of millions of dollars worth of crops. Nebraska farmer. Ben Stephan says he dodged the worst of it. But if prices and trade continued to slump he along with many others may have to file for chapter twelve that's because this special bankruptcy code helps. Farmers resettled, dead and stay in business. And if that happens, lawmakers won't be ready or more going to push ahead with reform chapter twelve bankruptcy because we need to update that law. I was Senator Chuck Grassley says he wants to make sure more farmers can qualify for chapter twelve bankruptcy to do that. He's proposing more than doubling the amount of debt. They're allowed to take on from around four million dollars to about ten million. For NPR news. I'm Esther Hoenig. An ester story came to us from harvest public media reporting collaboration focusing on agriculture and rural issues. Support for NPR and the following message. Come from the seventh annual charm city bluegrass festival with the bridge deer tick steep canyon, Rangers and the Jeff Austin band, April twenty six and twenty seventh at Baltimore's druid Hill Park tickets at charm city, bluegrass dot com.
Tennessee Whiskey Relies on Missing Ingredients
"This is scientific American sixty seconds science. I'm Christopher Dodd Yata all bourbon, whiskey doesn't have to be made in bourbon county Kentucky. But it does have to be produced from at least fifty one percent corn. And it has to be aged in unused charred oak barrels Tennessee, whiskey on the other hand must be made in Tennessee as the name implies. And in addition to the steps that create a bourbon, the distilled whiskey undergoes, another one called the Lincoln county process where you take your fresh whiskey this lie and you filter through sugar maple charcoal. It's also called charcoal mellowing trend. Curly is a graduate student in food science at the university of Tennessee institute of agriculture and just for the record personally, I prefer bourbon whiskey filtration through charcoal made from the wood of the sugar maple tree is known to mellow the flavor of Tennessee whiskeys like Jack Daniels, but the underlying chemistry was a bit. More of a mystery. So curly teamed up with the sugar Lynn's distilling company in Gatlinburg Tennessee to. Put their whiskey to the test. He used gas chromatography coupled with actual human sniffing to identify about three dozen aromatic compounds contributing to the whiskeys flavor profile, he then tracked the quantities of four of them to branch dock halls and two ethyl esters before. And after the Lincoln county process turns out the charcoal stripped out, a third of the branched alcohols in nearly half of the ethyl esters curly's advisor food chemist, John Peterman Afo. Hey, co message is that the branched alcohols and at the last Jewish that we analyzed in this study decreased, and that the distillate was smoother tasting and less harsh after the Lincoln county process. The researchers presented the work at an American Chemical Society meeting in Orlando and the goal. Curly says is to take some of the guesswork out of making great, whiskey, especially when the stakes are high. There was a head to Stiller at one of the big bourbon distilleries who said you really only get two chances to make a fifteen year old with. Munaf again, basically, we're just optimizing the tools to help the distillers get to the flavor profile that they want as for the flavor profile. He wants well. I'm not saying that Tennessee, whiskey is better just is. Thanks for listening for scientific American sixty seconds science. I'm Christopher Don. Yata?
"esters " Discussed on TalkRadio 630 KHOW
"Ester. This message is brought to you by glory days grill. You may know us for our great, burgers and wings but glory days pros mix it up with fresh, cedar planks, salmon, cut in house and grilled to perfection or sizzling juicy stakes media ribs, we even have handcrafted salads and sandwiches buyer talented chefs to change tastes good. We promise experience the glory days grill menu in all its glory glory days grill. Great food, good sports. Text maven maven new boyfriend. No, just Vicki my free hair appointment with then. Wait, did you say free? Yeah. Just takes world two three four six four nine to make your appointment with the maven expert. Silence texts world two three four six four nine right now when you buy maven hair stylists put it in free with the free shampoo breakdown sewing and Silje free here is so expensive. And by the time, you get to put in everything else that has Andrew here. Always look so good. Now, you know, my secret is the top of the line. Here company is backed and worn by celebrities. They offer the highest quality of virgin here fast free shipping plus top notch certify styles. Expertly install your maven here. And if you're in the Clintons all Whigs mavens got you covered there too. I wish you knew about even sooner. It's not too late. But you better make your appointment now. Text world three four six four nine. That's W O R L D three four six four nine. You want to talk about regarding addiction anything like how do I approach an attic? What does the cost what kind of treatments are there? What does the Raleigh house? Do that's different than others. What can we do? What? How do we confront them any questions? There's nothing off base. You can call.
Trade Deficit Soars to Record Level
"Street now stocks were mostly lower in early trading. Esters digested the latest trade deficit and job creation numbers and we're keeping tabs on U S. China trade talks the US trade deficit shot up. Nearly nineteen percent in December the highest monthly trade deficit in a decade and setting a record high annual trade gap of six hundred and twenty one billion dollars trade deficit with China Mexico and the European Union all surged to record
"esters " Discussed on KIIS 102.7
"Pack again. Downtown. What? Bill. I'm a dangerous, man. What? Second. Visit. Hashtag. Dangerous. You bet. Like. That'd be like. Bragging. Channel now. Just. Saddest thing going now. Esters? Nine. Get to him. Not your fault..
"esters " Discussed on KIIS 102.7
"Dose had been as close. Rina's? International. Day. I gotta say. Spain. Going now. Esters? Runaways? Two. Every time I guess through. Sabotage. I really want to say that. I want to let you..
Amazon H2Q Sparks Long Island City Real Estate Boom
"Amazon has selected northern Virginia and Long Island City New York to be the locations for the company split second headquarters, but even before the decision Amazon's interest in Long Island city had sparked a condo buying frenzy in the area located in the queens borough of New York, if it seems reminiscent of the pre crash property, boom. Well, that's probably accurate. Joining us with more on the story is Wall Street Journal real estate reporter, Josh barb anelle. Josh you right that until recently the Long Island city property market was pretty sleepy. When exactly did client start flooding brokers with inquiries. It was about a week ago. When the first word came out that Amazon was close to a decision that might involve Long Island city, and it began almost immediately like that night and the next morning brokers were getting calls from mostly. Esters at I who will looking to make offers on apartments later people who are looking to live there themselves. Also got the idea and started showing up in significant numbers. Yeah. How busy has this been for brokers? Demand. Must have or inquiries must have grown exponentially. It was incredibly busy. There were several stories predicting massive changes in both Long Island city and Virginia if this happened, and I kind of waited to see when we would get some documentation of this actually proof that it was really happening. And I came rather quickly by Thursday evening. I heard from a broker that all the appointments to look at apartments there through the weekend were failed. And there was no way they could get in except to go to open houses, you describe one example, this this building, I guess is going up. It's the glass building that's going up Jackson avenue in Long Island city called the gallery. Yes. And their sales manager gave me. A week by week reporting on the weekly visitors and in the week before this Amazon rumor emerged they had thirty three visitors or so for the entire week in the week after actually on the weekend after they have hundred visitors nearly a hundred visitors who they saw in their sales office in groups and individually, and they turned away sixty three people who left their names, and they were going to call them have them come back after that. And there is another broker that you talk about this broker at modern spaces and this person oversee sales at at court. I believe in is it's an eight story condominium that went on the market in August. And even before the decision went down prices were expected to go up. And I think she sold twenty units via text while the head of the firm says his personal context, including people he hadn't seen in seven or eight years texted him and said, we're interested in I don't know whether one owner at w-. Wants to buy ten of them or there were twenty individual purchasers, but he claimed to have an essence taken their offers, and they were gonna make deals and we'll see what happens at the court. What actually happened is after they thought it seeing traffic the developers began the process of increasing prices somewhat. We don't have much so that that was a direct result of the Amazon intrigue before the announcement. And there are hundreds of new condominiums on the market in Long Island city and dozens of resale apartments, and I am magin that business had been saw for these units. And for these condos for for quite a while because the the market has been so sleepy until now right Long Island city when they began with development there about decades ago began as a condo neighbourhood and after two thousand eight it's which to being doing rental buildings only and only in the last year or two. Have developers began investing again in condominiums and the market was like other places in the city was soft and that reversed completely hundred eighty percent when the rumors started circulating as mentioned before Josh one real estate agent told you reminded him of New York's condo, boom, just before the market crashed in two thousand eight. Yeah. The idea was it wasn't that? It'd be for the crush. It was a period when there was a frenzy and some buildings had people lining up at the sales office before the open the first day with checks in hand for deposits. It's not quite like that yet. But they felt it went from being a buyer's market had been to a very intensive seller's market all at once. And even before people even sure that Amazon was gonna make the move.
"esters " Discussed on The Peter Attia Drive
"Triglycerides the stored energy in your liver and cholesterol esters the stored cholesterol in your liver cholesterol. I think I mentioned me for binds to the cholesterol, ester binds. The or free cholesterol binds to the ape obeef. I, some of the cholesterol will be terrified even in the circulation some in the liver via a cat ends on. And so once you get the little primordial spiritual via LDL than triglycerides are transferred in using and Tiki Microsoft truck, let's transfer protein, and now you got a real via LDL ready to be shipped out other as it passes through something called the space, which is a little space between her Pata sites and the plasma other April proteins. Join Nair many of them as soon as that nascent VOD l. or whatever you wanna call it interest plasma, a ton of the April proteins. Just leave your HDL plot. As one of the functions of shows remember, I told you transport proteins. They transport a ton of these proteins that are involved with liposuction catabolism. So see two jumps off of. HDL's e jumps off HDL's and goes right onto the surface of VOD l. if it was not put there as pastor and space this so and they all determine the cata Bolic faded at veal DO particle. So fiber aids through several mechanisms. One toget- is an enzyme involved with the synthesis of triglycerides. You know, it's adding fatty acids to glycerine. Fiber are potent hitter that you just stopped triglycerides production with fibrous omega three fatty acids work in a similar way. So they deplete the hypnotic pool of triglycerides and you're gonna make less via LDL particles. Remember a fiber is not gonna blow away your LDL pay a statin does, but it's going to blow eight, ten fifteen percent reduction in part depending on triglycerides richness. Not the serum triglycerides level, but the trigly- snow richness of the core. So that's one of the, where's the backup of. Free fatty acids because at some point, if you're not synthesizing as much triglycerides, but you still have you still have enough Eddie said, you're absorbing fatty acid your a site storm, but is there a hip haddock backup of fatty acids noble synthesis. So in other words, this would not decrease novelty if you had a patient because because at first blush you'd think, well, five rates should be able to reduce fatty acid to reduce thought that for years, but it's just never been proven in a trial that that alone would do it. Whereas actually Zetter my has more Gada on reducing fatty liver than a fibroid still and most people all blame fatty liver on triglycerides. It's a sterile that really cause a large part of the Lippo toxic city results in injury to the sills and your liver..
President Trump, Kim Jong Un will meet 1-on-1 in historic Tuesday summit
"A day and it starts now president trump met with singapore's prime minister lee sean long ahead of his summit with north korean leader kim jong un the president and the prime minister lee held bilateral talks at singapore's donna palace prime minister lee said it was a quote real honor to be with mr trump president trump starts denuclearization talks with kim tomorrow and what will be one of the most closelywatched summits in history kim jong un has arrived for the talks with president trump a meeting hard to imagine just months ago there is a lot of concern among those that have studied this issue carefully people who have studied and worked on the north korean issues intelligence experts foreign policy experts there is concern about how much the president knows about the details of any possible agreement that's abc's chief white house correspondent jonathan karl reporting from singapore todd ant abc news meet nightclub ester of talon wealth management the reason i really really liked to sit down with individuals is everybody's situation is different you have to find a way to navigate through all the information and then coming up with that list of what you need it applies to you very very specifically take a moment to sit down and look at what you're doing and let's make sure that your plan is right.
YouTube shooting: Woman shoots 3 before killing herself in San Bruno, California -- live updates
"Shots fired during the lunch hour at the video colossus youtube the upturn chairs the bullet casings and the police emergency calls nine one cherry now tragically familiar but not this a female suspect that's what we were told you we believe to be so quick to female with the investigation is ongoing this is believed to be the first female mass shooter since at least twenty ten the first call came in at twelve fortysix local time two minutes later police arrive searching for the shooter this is very esters encounter voice flee from the building very chaotic as you can imagine police moving forward finding hundreds of youtube employs their hands raised teams proceeding to clear the building and searching each employee by the college junior and ten renault accolades this man tended to one of the winded at a nearby business a gunshot wound site play like attorney kate on her to try to help her then came and then they took her away but a realtor kit of on her spills and police reporting at least four victims had been hospitalized and mack up and joins us now matt as you reported police say they found four victims what do we know about the victim's condition right now right now we've spoken to one of the major hospitals treating them san francisco general they say they have received one male in critical condition another female in serious condition and a third person another female in fair condition and right now police are just trying to figure out what happened here and figure out the actual nature of this attack tom it's all still so fresh.
Israel vows tough response to Gaza protests
"Wbz news time to twenty a computer glitch grounds flights and also causes massive air travel delays across europe cbs's vicki barker reports from the foreign desk in london on the technology that caused the problems most europeans probably had never heard of the enhanced tactical flow management system they have now the technology that keeps europe's crowded skies safe and efficient is on the blink and the folks at euro control haven't been able to restart it result about ten percent of flights grounded across forty one countries potentially affecting half a million air passengers vicki barker cbs news at the foreign desk in london israeli's military now vowing to maintain its tough response to hamasled mass protests near the border of israel and gaza the country's defense minister gave a warning today to those trying to breach the border saying that they're putting their lives in danger eighteen palestinians were killed by his rayleigh troops last friday hamas however says the border protests will keep going for at least six more weeks in downtown boston today a group of young jewish people chain themselves to the israeli consulate this to show support for those protests as wbz's kim tunnicliffe reports several of the protesters were led away in handcuffs they chain themselves to the front entrance of the park plaza building where the israeli consulate is located eight protesters were eventually arrested by boston police carted off in handcuffs they were there to protest the israeli army's killing of seventeen palestinians in a demonstration in gaza on friday elisa kaplan from jamaica plain was one of the protein esters who was not arrested by them putting their bodies on the line that really demonstrates our commitment to freedom and dignity for all people and really demonstrating how atrocious we found the killings of the palestinians in gaza and i think that was really clear wbz has tried unsuccessfully to reach the israeli consulate's office in boston kim tunnicliffe wbz newsradio.
"esters " Discussed on Effectively Wild: A FanGraphs Baseball Podcast
"I don't know how good the berge are going to be in 2018 and and henceforth but they were eighty two and eighty in 2014 five recall that was a year they were kind of in the hunt to win the division for wild than they bottomed out later on and then 2015 in 2016 they took deliberate steps back they began the regal than last year they won eighty six games and and this year clearly they think they are good enough to finish above five hundred and win this is all said and done the brewers might have handled there rebuild in a far less painful way than even the astra's in the cubs who graded they'd won their world series of they've got the jerry on top but we could have a new example of a model rebuild right here's the milwaukee brewers who were not they're not a team like the cubs that has that amount of resources now granted the astra's don't have that many resources compared to other teams so you know astra's urged right there is may be a model rebuild as well but the brewers did it in in even less painful way which is remarkable yes definitely yet i don't know whether it will pay off in the way that the cubs and astra's re bildt's did but there's definitely something to be said for never having to go through the fifty in sixty wind seasons season i don't know how many teams i mean if the brewers don't win a world series with this team that they've constructed then i guess most fans ends most future front offices would rather have the astor's and cubs rebuild in its entirety than the brewers one but certainly up to the point of getting could again you'd much rather have the brewers path than the esters her recovery path i don't it's maybe even harder to replicate i think it's that's one of the reasons why i wrote about it last year is that it was so impressive that the brewers seemed to be going from bad to good again without really having a stage of of being very bad so that's that's tough to do and i think they should be recognized for that if in fact they don't take a step back and they may have been in line to take a step back but now with yellow church and with cain and maybe with some pitcher or pitchers the.
"esters " Discussed on WGTK
"Yeah and that's i mean it's an evolving phenomenon dennis because of people like george will and max neuter beyond that even i mean they've gone to the next level where they're questioning uh not just the message the messenger but the messenger supposedly is so bad that the message itself now is not acceptable and uh and so george will is swept the republican party and so he really doesn't have anything in common with people who would vote for trump and max food is gone to the other side almost so i think we it involves foot people dig down and they feel more orphan from their twenty four constituencies and base and they look around them and they end up on msnbc beat basically uh but the progressive message and it's very sad that you don't know whether it was they were always progressive mcveigh nearly scraped off by trump or whether the anger or whether it's career esters culturally putt driven the anger is such that they're they've renounced what they wrote and said for twenty years is there anyone else at hoover who thinks like you yes shelby steele wonderful wonderful a bike and tom sold course tom rights that they're skeptical but he so that essentially this there were no whites think like you in your book which is wonderful all the almost glided of viktor keep up the gregoire thank you fairview your will.
"esters " Discussed on KSFO-AM
"The experts said that addis is does kind happen he said sometimes more dramatic but it also happens during heavy rain snow melt cold temperatures the freeze thought cycle can have a lot to do with it but they call it exfoliating believe it or add they say it happens a average of one a week drew generally not as dramatic as the one you ask today there there was somebody at the top yesterday that managed to capture the photo of yesterday's rockslide are i guess a giant chunk walling off which has more rockslide it looks like the valley covered with dust and smoke i mean it looks like smoke but it's just a giant plume of dust that you know debris it's very dramatic it's it's unbelievable and i guess a guy esters listener who are one of the reports earlier this morning were couple was driving out of the they they heard the rockfall they were park they're driving who the park and they were getting out of there and they heard the rockfall winner she said her husband get out of your quite quick quicker quick an awesome you just said how may pulled over the side he gotten hit on the head by one of the rocks one adult they had airlift him out of their the cut was so bad on the top of his head the first rockfall was estimated to be the size of five singlefamily homes that was that he said granite that was the first one hour now the second wind from yesterday apparently easily threetimes that size lives hiker says so the second one much bigger than the first amazing he added really is and here as i said geologist comex fully asians they say that as temperature rises from morning to afternoon the thin outer layer the rocks moves ever so slightly way from.