5 Burst results for "Dr Donald Kohn"

"dr donald kohn" Discussed on KQED Radio

KQED Radio

05:45 min | 2 years ago

"dr donald kohn" Discussed on KQED Radio

"York Times national baseball writer Tyler Kettner, you talked to hundreds of pitchers about what they throw and how they try to get a mental edge over the hitters. They face. His new book is K a history of baseball in ten pitches. Join us. Rush air Thursday afternoon. One pm Thursday evening seven PM on K Q E D. I'm Marco werman each day. We give you the world. Into the center of the world is curious at total chaos in Venezuela right now. The world is surprising. These governments is completely the world is unexpected Japanese really have history today the world is right here. Join us. Join us Thursday afternoon beginning at two. Thirty years ago when he was a kid guy created a superhero. And now lo these many years, then I did is an Amazon is easy to the, hey, you're out it's easier to just the fate out because there's so much fatigue. I'm KAI Ryssdal. The tick, and it's returned to the small screen exam. Marketplace. Marketplace on Thursday afternoon at four PM. And since it's Thursday, we'll have political breakdown for you Thursday at six thirty pm with Maria logos. And Scott Shafer, they will talk with LA county. Labor federation, president rusty Hicks in LA, he represents some six hundred thousand workers. And now he is vying to become the chair of the California Democratic party, rusty Hicks, political breakdown again, Thursday evening, six thirty here on K Q E D public radio. From NPR news. It's all things considered. I'm Audie Cornish. Nelson Chang sometimes rare diseases allow for scientists to pioneer bold, new ideas. That's been the case with a condition that affects fewer than a hundred babies a year in the US, those babies are born without a functioning immune system and the quest to cure them as lead Vance's in technique called gene therapy NPR's, Richard Harris reports the disease is called severe combined immunodeficiency or skid met Portia Stanford. Pediatrician says you might be familiar with it. It was made famous I guess in the mid seventies. When the bubble boy was described in in documented documentary, and I think he captured the imagination of a lot of people David Vetter spent most of his short life in a plastic bubble to protect him from infection. He died at the age of twelve things have come a long way since then all babies born in the United States are now screened for this condition and standard treatment of bone. Marrow transplant succeeds more than ninety percent of the time when it's done promptly yet. Skit remains a source of great interest to researchers. This is one of those diseases in which there's probably more doctors and scientists studying the disease than patients who have the disease in the nineteen nineties European scientists actually cured it in some patients. Using gene therapy this technique involves removing defective. Blood cells from a patient inserting, a new gene with the help of a virus? And then putting this back into the body those cells than build up the patient immune systems, Dr Donald Kohn at UCLA says at first it looked really good at initially together. Twenty patients, they all had immune recovery. But over time five of them went on to develop leukemia. Scientists scramble to figure out how to inject new genes into cells without triggering that blood cancer, and they're cautiously optimistic they've succeeded since then there have been gradual improvements in the technique the latest advance involving eight infants shows that a short dose of chemotherapy. Maybe helped the new sales take root the infants ended up with apparently healthy immune systems. I am thrilled to CDs. Outstanding results Eveline among Sasha at Saint Jude's Children's Research Hospital in Memphis is first author of a paper reporting these findings in the New England Journal of medicine to be able to see these babies in my clinic now is told l'urss Israeli very rewarding. They live normal lives are not any different from my daughter's today most children with skid who get a bone marrow transplant also need ongoing treatment, including lifetime injections of antibodies. Jennifer puck a pediatrician at UC San Francisco and a study collaborator says infants got the newest gene therapy don't need that medication and they're growing. Normally they're getting cold like everybody else and they get over infection. So I would say that that is a cure. Of course, she adds that they'll be watched carefully for signs of leukemia. And to see if the effects of therapy are wearing off. In her mind. The key is finding these children early through newborn screening before they start to get life threatening infections that had typically been the case. And now we're seeing happy about little newborns who just look perfectly normal. This is not only good news for those rare families that disease provides a good opportunity for all those antics to develop even newer, gene. Therapy techniques, for example, instead of inserting a healthy, gene met Portius at Stanford. His used a powerful gene editing technique called crisper to correct the genetic error in skid blood cells. It works with human cells in a dish. And this really sets the stage then for testing the approach in a clinical trial. Hopefully in the next twelve to eighteen months all this makes the leukemia setback from the nineteen nineties feel like a fading memory Cohn at UCLA said for more than a decade. It seems that the field was a dead end. But no more just nice to see another success for gene therapy, Richard. Harris NPR news. It came to be known as v.

NPR leukemia Richard Harris UCLA United States rusty Hicks Marco werman KAI Ryssdal Audie Cornish Tyler Kettner Scott Shafer Amazon David Vetter LA county York Times severe combined immunodeficien writer
"dr donald kohn" Discussed on 90.3 KAZU

90.3 KAZU

04:36 min | 2 years ago

"dr donald kohn" Discussed on 90.3 KAZU

"Silly your childhood home can be an emotional transaction. Not least because the things you like about it might be a turnoff to buyers. Unfortunately, it seems like a lot of people these days they want a whole new house on the anti people went off the shelf ready on resolve the house, you grew up in and today's housing market next. Marketplace. Stay with us for marketplace. That's coming up at five thirty tonight right here on KABC. You the time now four fifty. From NPR news. It's all things considered. I'm Audie Cornish. Nelson chain sometimes rare diseases allow for scientists to pioneer bold, new ideas. That's been the case with a condition that affects fewer than a hundred babies a year in the US, those babies are born without a functioning immune system and the quest to cure them has led to advances in technique called gene therapy NPR's, Richard Harris reports the disease is called severe combined immunodeficiency or skid met Portia Stanford. Pediatrician says you might be familiar with it. It was made famous I guess in the mid seventies. When the bubble boy was described in in Documenta documentary. And I think he captured the imagination of a lot of people David Vetter spent most of his short life in a plastic bubble to protect him from infection. He died at the age of twelve things have come a long way since then all babies born in the United States are now screened for this. Edition and standard treatment a bone marrow transplant succeeds more than ninety percent of the time when it's done promptly yet. Skit remains a source of great interest to researchers. This is one of those diseases in which probably more doctors and scientists studying the disease than patients who have the disease in the nineteen nineties European scientists actually cured it in some patients. Using gene therapy this technique involves removing defective. Blood cells from a patient inserting, a new gene with the help of a virus? And then putting the cells back into the body, though cells than build up the patient's immune systems, Dr Donald Kohn at UCLA says at first it looked really good and initially twenty patients, they all had immune recovery. But over time five of them went to develop leukemia to scramble to figure out how to inject new genes into cells without triggering that blood cancer, and they're cautiously optimistic they've succeeded since then there have been gradual improvements in the technique the latest advance involving eight infant. Shows that a short dose of chemotherapy helped the new cells take root, the infants ended up with apparently healthy immune systems. I am thrilled to CDs. Outstanding results Eveline among Sasha at Saint Jude's Children's Research Hospital in Memphis is first author of a paper reporting these findings in the New England Journal of medicine to be able to see these babies in my clinic now as toddlers Israeli very rewarding they live normal lives. There are not any different from my daughter's today most children with skid who get a bone marrow transplant also need ongoing treatment, including lifetime injections of antibodies. Jennifer puck a pediatrician at UC San Francisco and a study collaborator says infants who got the newest gene therapy don't need that medication and they're growing. Normally they're getting cold like everybody else, and they take it over infection. So I would say that that is a cure. Of course, she adds that they'll be watched carefully for signs of leukemia and to see if the. Of the therapy are wearing off in her mind. The key is finding these children early through newborn screening before they start to get life threatening infections that had typically been the case. And now we're seeing happy bouncy little newborns. Just look perfectly normal. This is not only good news for those rare families the disease provides a good opportunity for all the scientists to develop even newer, gene therapy techniques, for example, instead of inserting a healthy, gene. Matt Portius at Stanford. His used a powerful gene editing technique called crisper to correct the genetic error in skid blood cells. It works with human cells in a dish. And this really sets the stage than for testing the approach in a clinical trial. Hopefully in the next twelve to eighteen months. All this makes the leukemia setback from the nineteen nineties feel like a fading memory Cohn at UCLA said for more than a decade. It seemed that the field was a dead end. But no more just nice to see. Another success for gene therapy. Richard Harris, NPR news. It came to be known as Chella..

David Vetter leukemia NPR UCLA Richard Harris United States Audie Cornish Matt Portius New England Journal of medicin Eveline severe combined immunodeficien Dr Donald Kohn Nelson Portia Stanford Cohn Jennifer puck
'Bubble Boy' Disease Helped By Advances In Gene Therapy

Fresh Air

03:54 min | 2 years ago

'Bubble Boy' Disease Helped By Advances In Gene Therapy

"Sometimes rare diseases allow for scientists to pioneer bold, new ideas. That's been the case with a condition that affects fewer than a hundred babies a year in the US, those babies are born without a functioning immune system and the quest to cure them has led to advances in technique called gene therapy NPR's, Richard Harris reports the disease is called severe combined immunodeficiency or skid met Portia Stanford. Pediatrician says you might be familiar with it. It was made famous I guess in the mid seventies. When the bubble boy was described in in Documenta documentary. And I think he captured the imagination of a lot of people David Vetter spent most of his short life in a plastic bubble to protect him from infection. He died at the age of twelve things have come a long way since then all babies born in the United States are now screened for this. Edition and standard treatment a bone marrow transplant succeeds more than ninety percent of the time when it's done promptly yet. Skit remains a source of great interest to researchers. This is one of those diseases in which probably more doctors and scientists studying the disease than patients who have the disease in the nineteen nineties European scientists actually cured it in some patients. Using gene therapy this technique involves removing defective. Blood cells from a patient inserting, a new gene with the help of a virus? And then putting the cells back into the body, though cells than build up the patient's immune systems, Dr Donald Kohn at UCLA says at first it looked really good and initially twenty patients, they all had immune recovery. But over time five of them went to develop leukemia to scramble to figure out how to inject new genes into cells without triggering that blood cancer, and they're cautiously optimistic they've succeeded since then there have been gradual improvements in the technique the latest advance involving eight infant. Shows that a short dose of chemotherapy helped the new cells take root, the infants ended up with apparently healthy immune systems. I am thrilled to CDs. Outstanding results Eveline among Sasha at Saint Jude's Children's Research Hospital in Memphis is first author of a paper reporting these findings in the New England Journal of medicine to be able to see these babies in my clinic now as toddlers Israeli very rewarding they live normal lives. There are not any different from my daughter's today most children with skid who get a bone marrow transplant also need ongoing treatment, including lifetime injections of antibodies. Jennifer puck a pediatrician at UC San Francisco and a study collaborator says infants who got the newest gene therapy don't need that medication and they're growing. Normally they're getting cold like everybody else, and they take it over infection. So I would say that that is a cure. Of course, she adds that they'll be watched carefully for signs of leukemia and to see if the. Of the therapy are wearing off in her mind. The key is finding these children early through newborn screening before they start to get life threatening infections that had typically been the case. And now we're seeing happy bouncy little newborns. Just look perfectly normal. This is not only good news for those rare families the disease provides a good opportunity for all the scientists to develop even newer, gene therapy techniques, for example, instead of inserting a healthy, gene. Matt Portius at Stanford. His used a powerful gene editing technique called crisper to correct the genetic error in skid blood cells. It works with human cells in a dish. And this really sets the stage than for testing the approach in a clinical trial. Hopefully in the next twelve to eighteen months. All this makes the leukemia setback from the nineteen nineties feel like a fading memory Cohn at UCLA said for more than a decade. It seemed that the field was a dead end. But no more just nice to see. Another success for

David Vetter Leukemia United States Ucla Severe Combined Immunodeficien New England Journal Of Medicin Matt Portius Portia Stanford Eveline NPR Dr Donald Kohn Richard Harris Jennifer Puck Cohn San Francisco Memphis Saint Jude Sasha
"dr donald kohn" Discussed on KCRW

KCRW

04:05 min | 2 years ago

"dr donald kohn" Discussed on KCRW

"Us updated. With the news four fifty case yard NPR news. It's all things considered. I'm Audie Cornish nine sometimes rare diseases allow for scientists to pioneer bold, new ideas. That's been the case with a condition that affects fewer than a hundred babies a year in the US, those babies are born without a functioning immune system and the quest to cure them as lead to advance in technique called. Gene therapy. NPR's Richard Harris reports the disease is called severe combined immunodeficiency or skid. Matt Portia Stanford. Pediatrician says you might be familiar with it. It was made famous I guess in the mid seventies. When the bubble boy was described in in Documenta documentary. And I think he captured the imagination of a lot of people David Vetter spent most of his short life in a plastic bubble to protect him from infection. He died at the age of twelve things have come a long way since then all babies born in the United States are now screened for this condition and standard treatment a bone marrow transplant succeeds more than ninety percent of the time when it's done promptly it. Skit remains a source of great interest to researchers. This is one of those diseases in which there's probably more doctors and scientists studying the disease than patients who have the disease in the nineteen nineties European scientists actually cured it in some patients. Using gene therapy this technique involves removing defective. Blood cell. From a patient inserting a new gene with the help of a virus? And then putting this back into the body those cells than build up the patient's immune systems, Dr Donald Kohn at UCLA says at I looked really good at initially. I think of the twenty patients they all had immune recovery. But over time five of them went on to develop leukemia. Scientists scramble to figure out how to inject new genes into cells without triggering that blood cancer, and they're cautiously optimistic they've succeeded since then there have been gradual improvements in the technique the latest advances involving eight infants shows that a short dose of chemotherapy helped the new cells take root, the infants ended up with apparently healthy immune systems. I am thrilled to CDs. Outstanding results Eveline among Sasha at Saint Jude's Children's Research Hospital in Memphis is first author of a paper reporting these findings in the New England Journal of medicine to be able to see these babies in my clinic now as toddlers Israeli. Very rewarding. They live normal lives are not any different from my daughter's today most children with skid who get a bone marrow transplant also need ongoing treatment, including lifetime injections of antibodies. Jennifer puck a pediatrician at UC San Francisco and study collaborator says infants who got the newest gene therapy don't need that medication and they're growing. Normally they're getting cold like everybody else and they take over infection. So I would say that that is a cure. Of course, she adds that they'll be watched carefully for signs of leukemia and to see if the effects of the therapy are wearing off in her mind. The key is finding these children early through newborn screening before they start to get life threatening infections that had typically been the case and now are seeing happy bouncy little newborns who just look perfectly normal. This is not only good news for those rare families that disease provides a good opportunity for all the scientists to divert. Philip even newer, gene therapy techniques, for example, instead of inserting a healthy, gene. Matt Portia at Stanford has used a powerful, gene editing technique called crisper to correct the genetic error in skid blood cells. It works with human cells in a dish. And this really sets the stage then for testing the approach in a clinical trial. Hopefully in the next twelve to eighteen months all this makes the leukemia setback from the nineteen nineties feel like a fading memory Cohn at UCLA said for more than a decade. It seems that the field was a dead end. But no more nice to see another success for gene therapy. Richard Harris, NPR news. It came to be known as.

NPR David Vetter leukemia Richard Harris United States UCLA Matt Portia Stanford Audie Cornish severe combined immunodeficien Eveline New England Journal of medicin Matt Portia Dr Donald Kohn Jennifer puck Cohn Stanford San Francisco
"dr donald kohn" Discussed on KQED Radio

KQED Radio

04:40 min | 2 years ago

"dr donald kohn" Discussed on KQED Radio

"An estimated twenty five thousand of them are in the San Francisco Bay area here from some of the bay area's meeting voices on issues surrounding homelessness. Meena Kim leads a panel of experts to discuss the state of the crisis. How we got here where we're headed next tonight at eight PM on. Real person fiction has got millions of people reading and talking. I'm Joshua Johnson. The impact of fan fiction about real people next time on one A B with us for one a tonight at eleven here on kqed public radio. From NPR news. It's all things considered. I'm Audie Cornish Chang. Sometimes rare diseases allow for scientists to pioneer bold, new ideas. That's been the case with a condition that affects fewer than a hundred babies a year in the US, those babies are born without a functioning immune system and the quest to cure them has led to advance in technique called gene therapy NPR's, Richard Harris reports the disease is called severe combined immunodeficiency or skid met Portia Stanford. Pediatrician says you might be familiar with it. It was made famous I guess in the mid seventies. When the bubble boy was described in documented documentary, and I think he captured the imagination of a lot of people David Vetter spent most of his short life in a plastic bubble to protect him from infection. He died at the age of twelve things have come a long way since then all babies born in the United States are now screened for this condition and. Standard treatment of bone marrow transplant succeeds more than ninety percent of the time when it's done promptly yet. Skit remains a source of great interest to researchers. This is one of those diseases in which there's probably more doctors and scientists studying the disease than patients who have the disease in the nineteen nineties European scientists actually cured it in some patients. Using gene therapy this technique involves removing defective. Blood cells from a patient inserting, a new gene with the help of a virus? And then putting the cells back into the body those cells than build up the patient immune systems, Dr Donald Kohn at UCLA says at first it looked really good at initially together. Twenty patients, they all had immune recovery. But over time five of them went to develop leukemia. Scientists scramble to figure out how to inject new genes into cells without triggering that blood cancer, and they're cautiously optimistic they've succeeded since then there have been gradual improvements in the technique the latest advance involving eight infants shows that. Short dose of chemotherapy, helped the new cells take root, the infants ended up with apparently healthy immune systems. I am thrilled to see outstanding results. Eveline among Sasha at Saint Jude's Children's Research Hospital in Memphis is first author of a paper reporting these findings in the New England Journal of medicine to be able to see these babies in my clinic now as toddlers Israeli very rewarding. They live normal lives are not any different from my daughter's today most children with skid who get a bone marrow transplant also need ongoing treatment, including lifetime injections of antibodies. Jennifer puck a pediatrician at UC San Francisco and a study collaborator says infants who got the newest gene therapy don't need that medication and they're growing. Normally they're getting cold like everybody else. Take it over infection. So I would say that that is a cure. Of course, she adds that they'll be watched carefully for signs of leukemia and to see if the effects of the therapy are wearing off in her mind. The key is finding these children early through newborn screening before they start to get life threatening infections that had typically been the case. And now we're seeing happy bouncing little newborns who just look perfectly normal. This is not only good news for those rare families the disease provides a good opportunity for all the scientists to develop even newer, gene therapy techniques, for example, instead of inserting a healthy, gene. Matt Portia at Stanford. His used a powerful gene editing technique called crisper to correct the genetic error in skid blood cells. It works with human cells in a dish. And this really sets the stage then for testing the approach in a clinical trial. Hopefully in the next twelve to eighteen months all this makes the leukemia setback from the nineteen nineties. Feel like a fading memory Cohn at UCLA said for more than a decade. It seems that the field was dead end. But no more nice to see another success for gene therapy. Richard Harris, NPR news. It came to be known as.

leukemia NPR David Vetter UCLA Richard Harris United States San Francisco Bay Matt Portia Joshua Johnson Meena Kim Audie Cornish Chang Eveline severe combined immunodeficien Portia Stanford New England Journal of medicin kqed Dr Donald Kohn