35 Burst results for "Colon"
'Dear Christian: Your Fear Is Full of Crap' With Doug Giles
"I have as my guest right now, my friend, Doug, Giles, Doug, you encouraged me, just seeing you and hearing your voice. Thanks for being on. Eric, good to be with you, big dog. You're looking very dapper, man. Okay, the title of your books are sometimes they're hard to read. I'm holding the book here. It is dear Christian colon. It's a business letter. Dear Christian, you are fear is full of, I believe, the Greek word is scuba on poop. Dear Christian. Your fear is full of crap. Now, did you know that where the term crap comes from? Because people think it's like a bad word. It's not a bad word. Thomas crapper invented the flush toilet. He was an English man. He invented the flush toilet, so we would say, where are you going? I'm going to the crapper. And it's kind of taken on this weird meaning, but that's what it means. So you do not pull punches. So your book is titled dear Christian, your fear is full of crap and you have second Timothy one 7. So I don't remember offhand what a second Timothy one 7. Why is the title the title? Yeah, it's one of my favorite scriptures, Erica, especially in this day of mass delusional psychosis. It's where Paul told Timothy, who was raised by his mom and his grandmama, and he had a church in Ephesus. He's like, hey, Timothy, God didn't give you a spirit of fear, but of power, love, and a sound mind. And I'm looking at the church and how they embrace like Mark McDonald said a mass delusional psychosis from 2020 to 2021 plus. I've got a buddy up in Ottawa, Canada. His family goes to church up there. They're still masking up. Eric, they're still acting like, you know, the Bubonic plague is unleashed, you know, and that we've got to cower and fears poor little Christians and stuff. And you look at the scripture, the injunction to fear, I think it's the most replete command coming off the lips of the prophets and the apostles and Christ Jesus himself. And yet Christians decided that they're going to adopt fear instead of live bold wild and free. And the only people that I see in the scripture, Eric that have fear on them, according to, again, the scripture. I hate to bring that into it. It is the wicked.
Doug Giles Shares the Premise of 'Psalms of War' Book
"Of war that we discussed a few months ago. Tell us what that is in case people missed that program. Yeah, the book songs of war prayers are literally kick ass. It's a compendium of 28 imprecations. Wait a minute, wait a minute. Wait a minute. See, I can't let that go. That's so sums of war colon, prayers, go ahead, prayers that literally kick ass. That literally kick ass. Ladies and gentlemen, this is a family program. We have no problem using the term balaam's ass on this program. This is so funny. So sums of war prayers that literally kick us. These are called the imprecatory psalms, right? These are the ones where we're praying judgment down on evil on our enemies. Right. Yeah, and a lot of Christians are like, oh, Eric and Doug, we can't do that, that's for Old Testament times where God was an old meanie and now we've got sweet and cuddly 7 pound 13 ounce baby Jesus. And he has nary a Pete bad to say about evil leaders in their imaginations. And unlike widow, I can read and when I read Christ in the scripture, Matthew 22 43, he said that the imprecatory psalms on two that David wrote was inspired by this person called the third person of the godhead, the Holy Spirit. And so a lot of Christians back off from these imprecation Eric, they don't want to pray these harsh prayers, but listen, if we've got implacable enemies that are impenitent, that they are spot well that the bad ideas and demonic powers, then we don't go nice with them. We pull out this 44 Magnum dirty hairy prayer. This tomahawk missile, and we launch it at the powers of darkness, and yes, sometimes there are some human collateral damage, but they're in the Bible,
How Does the Anti-Defamation League Define 'Racism?'
"And it's been pointed out that the anti defamation league once took the position and I quote that racism quote is the belief that a particular race is superior or inferior to another That a person's social and moral traits are predetermined by his or her inborn biological characteristics Racial separatism is the belief most of the time based on racism that different races should remain segregated apart one from the other I don't disagree with that I think that's a pretty damn good Definition you want to know the truth But it's pointed out by Jerry dunleavy the anti defamation league changed its definition of racism sometime in July or August of 2020 So what To this racism colon the marginalization and or oppression of people of color Based on a socially constructed racial hierarchy that privileges white people You see the old definition couldn't work They couldn't work Because the ADL has apparently concluded like the Democratic Party for whom it effectively is associated And the media and the rest that racism isn't about treating individuals equally regardless of their race or your race racism is about as the critical race the remarks have been burping up The white dominant society oppressing everybody else
Howard Hesseman, star of 'WKRP in Cincinnati,' dies at 81
"Actor actor actor actor Howard Howard Howard Howard Hesseman Hesseman Hesseman Hesseman has has has has died died died died from from from from complications complications complications complications from from from from colon colon colon colon surgery surgery surgery surgery according according according according to to to to his his his his manager manager manager manager has has has has been been been been was was was was eighty eighty eighty eighty one one one one marches marches marches marches are are are are a a a a letter letter letter letter with with with with a a a a look look look look at at at at his his his his life life life life hi hi hi hi this this this this is is is is Dr Dr Dr Dr Johnny Johnny Johnny Johnny fever fever fever fever just just just just doing doing doing doing my my my my job job job job Howard Howard Howard Howard has has has has been been been been had had had had been been been been a a a a radio radio radio radio DJ DJ DJ DJ which which which which made made made made him him him him all all all all the the the the more more more more believable believable believable believable in in in in his his his his most most most most famous famous famous famous role role role role as as as as Dr Dr Dr Dr Johnny Johnny Johnny Johnny fever fever fever fever on on on on WKRP WKRP WKRP WKRP in in in in Cincinnati Cincinnati Cincinnati Cincinnati he he he he earned earned earned earned two two two two Emmy Emmy Emmy Emmy nominations nominations nominations nominations for for for for that that that that role role role role we're we're we're we're too too too too smart smart smart smart to to to to go go go go to to to to dances dances dances dances still still still still has has has has been been been been also also also also found found found found success success success success playing playing playing playing history history history history teacher teacher teacher teacher Charlie Charlie Charlie Charlie Moore Moore Moore Moore on on on on the the the the sitcom sitcom sitcom sitcom head head head head of of of of the the the the class class class class and and and and does does does does and and and and Romano's Romano's Romano's Romano's husband husband husband husband on on on on one one one one day day day day at at at at a a a a time time time time he he he he had had had had roles roles roles roles in in in in this this this this is is is is spinal spinal spinal spinal tap tap tap tap Billy Billy Billy Billy Jack Jack Jack Jack and and and and doctor doctor doctor doctor Detroit's Detroit's Detroit's Detroit's actor actor actor actor Howard Howard Howard Howard Hesseman Hesseman Hesseman Hesseman has has has has died died died died from from from from complications complications complications complications from from from from colon colon colon colon surgery surgery surgery surgery according according according according to to to to his his his his manager manager manager manager has has has has been been been been was was was was eighty eighty eighty eighty one one one one marches marches marches marches are are are are a a a a letter letter letter letter with with with with a a a a look look look look at at at at his his his his life life life life hi hi hi hi this this this this is is is is Dr Dr Dr Dr Johnny Johnny Johnny Johnny fever fever fever fever just just just just doing doing doing doing my my my my job job job job Howard Howard Howard Howard has has has has been been been been had had had had been been been been a a a a radio radio radio radio DJ DJ DJ DJ which which which which made made made made him him him him all all all all the the the the more more more more believable believable believable believable in in in in his his his his most most most most famous famous famous famous role role role role as as as as Dr Dr Dr Dr Johnny Johnny Johnny Johnny fever fever fever fever on on on on WKRP WKRP WKRP WKRP in in in in Cincinnati Cincinnati Cincinnati Cincinnati he he he he earned earned earned earned two two two two Emmy Emmy Emmy Emmy nominations nominations nominations nominations for for for for that that that that role role role role we're we're we're we're too too too too smart smart smart smart to to to to go go go go to to to to dances dances dances dances still still still still has has has has
AZ Senate Candidate Jim Lamon: 'It's Time for Washington to See Some Real Action'
"A friend of mine, someone who's been very generous to turning point USA and he's a great American Jim layman, and you're running for U.S. Senate in Arizona. Charley, it's time for Washington to see some real action on the U.S. Senate floor. Somebody's really going to stand up for America first, Arizona. I'm going there to make sure it happens. Well, I love to hear that. And so you built a business here in Arizona. Tell us about that. Well, a great foundation of 8 years ago, we brought in great guys from the colon gas industry, which I had led for many years. Second largest company in that industry was fortunate to not start it, but build it to what it was. And then bringing those guys over, seeing an opportunity that said there's a new form of energy that if we focus with utility types really strong power people, not looking at as a greeny thing, look at the power thing. The way of the potential for it to become the lowest cost power. And we've actually achieved that about 5 years ago. We hit parity with the lowest current then formed natural gas. We've continued to drive that down and today Charlie, it's half the price of natural gas. I'm a believer in American energy dominance, not just independence, as our past president said. Or asterisk, guys that are in there now would not believe it, but we just have a strong belief that we've got so much resources in the country. Add solar to that mix. We should absolutely not be doing what the Biden and Kelly administration are doing now. Begging Saudi Arabia for more fuel and just crazy things like that when we've got it all here.
Doctor recommends 'routine surveillance' after polyp removed from Biden's colon
"The Pollock removed from president Biden's Colin last week was benign the president's physician says it was a slow growing but potentially pre cancerous lesion that required no further action in a follow up memo doctor Kevin o'connor says the specimen was similar to one removed from Biden in two thousand eight he says routine surveillance which normally calls for another colon Naskapi in seven to ten years was recommended the Mayo clinic's website says most colon polyps are harmless but some can develop into colon cancer over time my
Colin Powell, First Black Secretary of State, Dies at 84 From COVID-19 Amid Cancer Battle
"Show. The first black U.S. Secretary of State and chairman of the joint chiefs of staff a major political historic cultural figure has died at the age of 84, general Colin Powell died of complications from COVID-19, according to his family. Of course, lots of controversy during his career. He went before the UN Security Council made the case for war against Iraq. He, of course, reveal himself to be an Obama supporter and to many of us who at one point thought he might be a viable Republican candidate for office, that was all scuttled when he confirmed that he was essentially a liberal. And our political differences with colon Powell don't change our respect for his life and his legacy and most important the pain and grief that his family is feeling at his loss.
Americans take largest lead against Europe in Ryder Cup
"The United States team is extended their lead other you're about that the second day's play in the Ryder Cup and head into the last day singles with a seemingly insurmountable six point lead once again the U. S. dominated the morning foursomes winning three of the four matches Europe mounted a mini fight back in the fold old matches winning two of the floor but it's still left the star studded American team with the dominant eleven to five point lead Dustin Johnson and colon or a comma continued to lead from the front remaining unbeaten for the week after adding two wins on the second day I'm Graham I got
The Nutritional Advantages of Oats
"Week. We're talking about oats. Oh so very good. I always feel that everyone needs to know oats. Yes absolutely so. What would you like to share about oats well other than than the the typical health benefits votes. There's actually two compounds in oats that i don't think very many people know about and so wanted to talk about those today but then also talk about the various types of oats. I think a lot of people have heard of these different types but they don't really know how they're prepared and what makes them different from each other. Good good good topic all right. Yeah so. I think most people probably know that oats Help lower cholesterol. He also helped to lower blood pressure and stabilize blood. Sugar levels have also been known to help people with diabetes. So that's a one of the important things and a lot of these benefits In the past were attributed to a particular type of fiber that's in the oats called beta glue can And that has really kind of gotten most of the attention in previous studies on oats and their health benefits. But we're coming to find out that Oats contain more than twenty unique polyphenol compounds which are like phytochemicals Called evanston reminds have strong antioxidant anti inflammatory and anti itching properties which is why people can use. Oats says a bath like if you get poison oak or poison ivy. Get that itchiness on your skin. The compounds and oats are known to reduce that. Oh so that's why that you know they're known for that And then there's a couple of other compounds called avino kocides that Together with the of the ninian through reminds and the venacuro sides. Which are i mean. Both of them are really hard to say. Yes but these are just polyphenol compounds They've also been shown to prevent colon cancer And also heart disease because they help to reduce the the production of nitric oxide in the artery and And also help with the smooth muscle in the artery. So they're they've been studied widely for this now.
No. 8 Notre Dame Survives Toledo 32-29 After Wild 4Q
"A Frank Notre Dame escape with the thirty two twenty nine win over Toledo one Jack Collins eighteen yard scoring strike to Michael Mayer with sixty nine seconds left the rockets took a twenty nine twenty four lead on freshman quarterback dequan Finn's twenty six yard bootleg TD run with one thirty five remaining it took Colin just twenty six seconds to directed three play seventy five yard touchdown drive colon threw for two hundred thirty nine yards and two touchdowns both to mayor Colin also was sacked six times fumbled once and had an interception return by Chris McDonald for a touchdown I'm the ferry
What 9/11 Did to One Family
"Is one the thousands of people who lost someone. They love on september eleventh. Two thousand one twenty years ago now. Big brother bobby. Mcilvaine died that day in new york city at the age of twenty six. He was like reaching out insane. I want to show you my office and was specifically onto the because it was the last time i saw. He told this story to atlantic staff writer jennifer senior. Who wrote about the mcilveen for the atlantic magazine. How did this story come into your life. Well i mean the most obvious way it came into my life is that i knew bobby mcilvaine. He was my brother's roommate in college. He was my brother's roommate in new york city. When they were young then starting out. I would visit my brother at princeton. Bobby would be there and he would. Just be ridiculously precocious charming. He wanted to be a writer. But one of the things that bob learned early in his life in publishing is that a lot of people in publishing came from upper middle class families. They had cushions of money beneath their toes. And bobby's family didn't have that kind of money and bobby knew. He wanted to make a living and so he went into corporate. Pr after two years of being in book publishing. And that's how bobby ended up working for merrill lynch and going to work conference on one of the top floors of the north building of the world trade center on the morning of september eleventh. I went down had coffee and was going over my work like many americans on that morning. Bobby's mom. Helen was starting workday as a teacher and they had the tv set on in every classroom. And i my knees buckled and light. I had to be helped. Bobby's dad bob senior. Also a teacher at the time was also at work. It was on tv. I call home. Of course i try to bobby. We get colon now. The phone was ringing. No one could reach bobby. His parents is friends his girlfriend or his brother. Jeff
Downward Facing Log
"Week's guided meditation for the constantly constipated the digestive warriors struggling for regularity and release the gluten go-getters. The defiant lactose intolerant. The horse lynn princesses. It doesn't matter that you're filled to the brim with undigested food. You still reach for that. Grew yay cheese. Canape and glass of temper neo. And that's what. I love about you girly if you find yourself stressed and overwhelmed by the state of your colon. This one's for you. If you find yourself cradling your belly like your the fucking octo mom but instead of eight babies your pregnant with a penny. Ar abbiati this one's for you if you're five laxative. Sti writhing in pain over your toto toilet rain. Too sweet baby. Hey seuss for even a micro bowel movement. This one's for you. I'd like for you now. Throw yourself on the bathroom floor. Preferrably close to a toilet schussed in case the syrupy smooth textures of my voice act has a natural auditory stool softener.
Husband of 'Real Housewives' Star NeNe Leakes Dies at 66
"A cast member of one of the real house wives shows is facing a personal tragedy back in twenty eighteen many leaks of the real housewives of Atlanta told her Instagram followers her husband had colon cancer and now he has died a family publicist and friend says Gregg Leakes died of the disease at home peacefully and surrounded by his wife and children he was sixty six years old the rep says the family is in deep pain with a broken heart Greg and many leaks were first married in nineteen ninety nine two years before their son Brett was born they split in twenty eleven but reconciled and remarried a second time a couple years later I'm Oscar wells Gabriel
Politico Reports Biden White Hosue Wants 'Props' on Afghanistan Efforts
"Here. Politico. Natasha Karaki White house to media. Yeah. Here we go. That's this is the actual headline, Not a joke. They're giving their instructions. White house to Media Colon. We want our props on Afghanistan. We want our props on Afghanistan. What are you? What are they? High school kids? Give me my props, Man. We want our props on Afghanistan. Don't know who that That's a quote from the White House or a quote from the reporter. But maybe always for a moment or two. Maybe right, like adults. I mean, there's only like a bunch of human lives at risk, you know? Just saying We want our props on Afghanistan. He caused the
Physical Symptoms of Fat Loss
"Know everybody's going to be different with with what they experience. I don't know about eight. I've never heard aches as like really something related to fat loss. I would be concerned about an ache inside your body that you're having all the time so i don't know about that left upper. I don't know what that could be. So if you continue to have pain check with your doctor about that. You're gallbladders on the right right. I was just thinking like what is on your left. Upper your stomach or small intestines just found the coolest picture. Ever the left upper. Is your spleen colon. Left kidney increase. Is that where your spleen is. According to this picture. Okay so in the left. Lumber is you're descending colon and left kidney so yeah you might wanna check with dr gallbladders on the right but okay. I didn't know where the spleen was. I couldn't answer that for a million dollars. I would have thought the spleen was somewhere else. It's also in the the center top so it's like the center top to the left. Yep so i wouldn't think that would be something to just let go or assume that it's normal. I would not seem normal as far as that. What you're talking about that beads. Or ps under the skin. Yes i actually felt that. What is that what's happening. I don't know but that's something that you that you'll you'll feel right under the skin like i'll feel it on my abdomen like a little. It feels like you're rubbing a little something. I don't know what's happening like. I said but yeah people have reported. It smells you know. Yeah you talked about. Dna about ketosis breath. You'll certainly have different odors in your breath. Based on that as far as things coming out in your sweat urine that could also be related to if you're detoxing something because we know that toxins are stored in our fat cells and so as you're releasing fat. Whatever was in their stashed away. Whenever you stored that fat is gonna come out and if you were exposed to something weird during that time your body packed it away. You might be smelling it as it's coming back out. I did notice when i was in deep ketosis that my urine would have a certain kind of a smell to it. That sounds lovely to say right. Let's talk about the way our urine smells. But anyway it's just something like whenever i would do atkins for example back in the day i would always try to do atkins. There was a certain smell but always been long with that after a few days. So tim
The Dangers of Sugar and Children
"We all know that sugar isn't good for us but really let's take a deep dive into why we really need to limit it in our kids diets. Oh absolutely well. I think you know. Sometimes we forget that during times of rapid growth like in childhood and adolescence that you know kids bodies are really sensitive to the influence of dieting activity. Because they're growing so fast they're seltzer turning over rapidly and that makes them especially vulnerable to the effects of food of physical activity and weight and even environmental damage that can occur and so we really need to put an emphasis during this time of rapid cell growth to make sure that the genes that are being activated or turning on towards health not towards a genetic susceptibility and sugar can actually displace some of these high value. Nutrition foods that play in essential role not just in growth but an immunity but also cognition and genetic expression okay. That's something that we don't typically hear about. And so what about the things we do hear about a lot in terms of childhood obesity. Type two diabetes like these things. We should be concerned about. Oh absolutely i mean first off anytime you look at childhood obesity wolf whether you know kids are really actually normal weight or an overweight. Too much sugar again. Just places. high value nutrition and micronutrients that can increase the inflammatory process that leads to chronic disease over time. Even kids who were teenagers who are overweight and adolescents have a significantly higher risk of colon cancer later in life. I mean we're even seeing precursors in heart disease in children. I mean if you look at like obesity in preschoolers. I think it's risen from around five percent in the early seventies like nineteen seventy two up to close to fourteen percent
Millet Can Work Magic on Diabetes
"Today. We look at the best way to control diabetes. Starting with a remarkable results of crossover study randomized hundreds of people with diabetes to one and a third cup of millet every day. How does millet come to the help of diabetics a substantial portion of the starch in millet is resistant starch meaning resistant to digestion are small intestine so providing a bounty for the good bugs in our colon all way more than more common grains like rice or wheat but pro-seoul and kodo millet lead the pack. What's going on the protein matrix in millet not only access a physical barrier but actually also partially sequester. Is your starch munching enzyme. In the milit- polyphenyls can also act as starch blockers. In and of themselves mill also has remarkably slower stomach emptying times than other starchy foods. If you know white rice boiled potatoes or pasta your stomach takes about an hour digestive before starting to slowly dump it into your intestines in two or three hours to empty about half way whereas you eat sorghum or millet and stomach emptying doesn't even start until two or three hours. I may take five hours to empty even half way note. This was for both thick millet. Porridge or just like millet couscous. So since the non viscous millet couscous meal was also equally slowing emptying. this suggests. There may just be something about millet itself that helps slow stomach emptying which should blunt the blood sugar spike bud. You don't know until you put it to the
Beacon Aims to Beat Zoom with Unique Encrypted Video Conference Technology
"One of the things about About beacon that That is unique. Is that you know that soon got caught red handed that they were not there calls are not encrypted and so what we did is we understand why the calls are not encrypted. We understand that they're using all technologies zoom as an accompanying. It's not new. A lot of people think okay. Why hurt his last year so they must be now. They've been around for a long time. Their technologies is actually anchored in a three versions before of what the current technology is. We're on the latest. So with that. What happens is that you cannot really do encrypted calls if you have a server in between so the moment the only way to do an encrypted cau- is what's called true end to end meaning there's no server in between and you're i'm connected to your computer your connected to my. We tried that for a long time to scale that up. It can't be scaled but we were lucky that we have been working with. Google and google developed something this call searchable streams and suitable streams as technology. That you can put a what to call me a middle server amid server between the call and it stays encrypted on the server and that's what we're using the first ones to use them if you're a journalist for example in you know one day you know you may be doing an interview with someone that their location has to be private. They're being pursued by some government or something weird. Do you do that and have them. On video. colon let snowden to russia that is not what we want in our world. We have two factor authentication we have biometric authentication token of education so we use all of the ways for you to protect your beacon account so that no one law that log into your account so beacon has that all built it.
"colon" Discussed on Unclassical
"Off together with you now. The love fathers out soon lost without you all we shared together might again now i can die happy with you beside me stay close one tweet. Charm and cling again to loving father. I was lost lady for like five minutes. Way was it. Like i was last. I was catching kepting a now. I can never knew. We actually couldn't breathe but i must be no more. Tell me now shortly. What happened to you. Young lips need not be eloquent. To which i'm taking these. Let's deliver a tell you it was his work. The story shall be his not mine. Ain't that the fucking light go kidnapped and yet it's the became got me story is also report story just coop. Cram for them. Well we should just explain. The goodman is the dodgers through friday night data died and he's also anyway so theseus much to say just like did swaps it so then chatting when eat. Passats freaking out. Because his son pollen icees waltzing towards him. And he's like is my son my worst enemy the man whose voice i most hate to hear fanling friendly very friendly. So this is a bit like dude. That's your son. At least see. I am seeing where we're yeah. Luckily guys nice. He says rock fried up and we'll get to see what he's bringing with him. Next time so i can hold a nice sees is the one who wants to start a war. He's he's getting together people. Everyone has this five both probably starting the walls. I'm not sure whether the gods have said is gonna go that way and they're gonna be as bad as each other beneficial slipping facts. It's nice. He's actually literally going around the city and freshwater would be nice. Yeah it'd be good that'd be you'd like to tool to represent you but i shall start war that just as bad as each up pretty bad with tie the nice what. What's his name at least the clean. Clean the song. Yeah antiques raw deal. He's just like oh you try us. But anyway that that is halfway through a big little halfway through oedipus at colonus so join us next time for the concluding hot. I guess we should do plug. I guess we should. I mean a for listening to us you probably saw the Uploading again social media's follow but yeah we're on all the social media's classical on tiktok route. It's grabber on twitter on facebook account. And you're ron wherever you put cost you can find it on classical. You've had your friends about that and we're also on patriot. We are hit your that. You can come and join us. You'll get some cool stuff. Plus extras on early episode. Relief to slender. And we'll see you next week. Guys fi..
"colon" Discussed on Webcomics Reviews And Interviews
"I now have an actual twenty dollars many twenty dollars here in essence all tiers get access to you know all tiers get access to a deservedly because we can actually go on and talk and talk about writing or pretty much anything upset Just has to be populated will start getting higher tiers you get things like stickers and you also get slightly more interesting stuff to play around with it the twenty dollars here however the executive producer you also mentioned you get any see there for about a year. You're going to be sweeping interesting work. You're going to pick up a mug. You're going to take t shirt. You're going to pick up. A canvas bag is well as the same interesting stickers that are not available to everybody else so i think it's worth it and like you said you're going to be seeing the block also expect to see me start actually producing books on a regular basis. I want to get back into the writing resource guide and actually just have instead of doing like a serious. You know you have to worry about all these plots and all that especially most people do the writing resource type stuff where it's basically they go through in all critiques. And all that. I was dealing with some of the weirdest stuff like how to use a whiteboard per manage. Trust me. i'm starting to really loved having whiteboard around. Even if it's like you're something you'd be plod out everything and just basically do like murder board and other stuff like that. So you're going to be seeing a lot of really good stuff. I think franz basically for me for over the next couple of months gave me interesting to see what happens. So yes. I'm back unhealthy of doing fine. And here's hoping For an actual suggestively year calculator have fun..
"colon" Discussed on Webcomics Reviews And Interviews
"Your lowe's your home depot your place in your home supplies. But the osmosis the welcome house had an interesting situation set up read nullius occasionally have actually generated you actually rent for emergency situations but the also had away with minue that well as physically figured it was skinny situation where they weren't going to be getting a lot of shipments in they would actually redo the menu a little bit that way they basically be able to shop open even if it was reduced menu because he will house metric or walk laos code essentially it who was green at is waffle house was operating in normal. They realized that they could be there for. Maybe a couple of weeks tops. That was cool. If on the other hand the waffle houses slipped into its a special menu so to speak and was actually raining out generators in with in essence in emergency mode. While they realized that they'd have to be there for a couple of months this waffle will house code yellow. there's also waffle house code red which basically meant that. Yeah they were going be there for a long long time maybe a year or two issues. At that point the waffle house had been closed up was not in operations and obviously the community was pretty much hurting. It was still there. It was just pretty much hurting. Well of course had you extrapolate into wa blouse. Black which is a post apocalyptic scenario the straight up. I'll be going through. Various different scenarios as cast progresses also looking at farming a lot of army israel's general tactics for survival and should be an interesting podcast. That's technically getting me. Three podcast right there. Wc w shiite flashes flash produced and waffle house code black. I've also debate starting up a fourth podcast which basically will be the movie. Survival guides the only vestry you need. Yeah yeah now. I've got work on slogan a little bit. The basic ideas that they should be a modified top ten list. And how you survive sir. John movie genres. You know if you're put into a like a horror movie around com a sex comedy action adventure. Prisoners will be whatever will be the top ten thing he'd be worrying about when it comes your survival. Yeah is going to be interesting. And you're gonna be seen a lotta ross. Suffice to say. The picture on page has been modified a little bit. Well first off only backup to the page with his basically. You're going to be seeing a lot of t-shirts there's going to be set up for the Movie survival guide. They're gonna cute little figures the logo and then basically the actual top ten very radiated forms. Those shirts gonna be available for sale in fact already are so. Check that out door. I'll be putting a lot of these show. These leasing the show notes on top of that be be developing some merchandise for the other podcast as well so far i've got lanyard for. Wpri and walk allows code black. I liked under cute lovable and definitely worth checking out. Also if you're going to be there anyway add there is of course the dreaded things i'm not allowed to do t shirt is well as dad. The dad grandpa uncle shirts. The concept behind the view was basically while dedrick kids grandpa's teach kids and uncles corrupt. Kids as soon they basically be practical experiencing with the. You're talking about anti interesting little shirt. Line adults for that. He was a play. She goes to redesign this shirts. But the key here is. I am working on some ucr merchandise. You're also you see some changes over the patriot on page yet. That's skimpy set up as well. It's already been putting some interesting changes first off..
"colon" Discussed on Webcomics Reviews And Interviews
"The supplies on hand also means i also have a kid to basically put into my bag was cool. Seeing is that hoster company basically does most of the cost me. Supplies basically does as sampler kits yet talking about weird concept young classes meet. We're gonna give you a sampler kit and one of the cool things about this cure curie seculow baggie with it that you can actually put in bags to basically supplies the basically was ago so this of course me got my wafers. I've got me. I've got my barrier rings and all that are already go at a moment's notice. Cut that in my back. That's my emergency situation. When i'm on the go and yeah actually. I use it a couple of times. You see me going from the bathroom. Get outta my way but let's you know it's that's where my health is right now. Yeah i'm doing pretty good. i've got fuller. it's just. I'm trying to overcome a little bit of inertia and i think i'm actually starting to come out of it. See you can expect a lot more out over the next couple of weeks with this. Basically means if i can actually start pulling stuff off so that want to ifficially You're going to start seeing our backup on thursdays. Once a week it can be While before i start doing interviews but we started seeing reviews by month. Also you're going to be starting she a little bit more. Yeah there's going to be no real for wpri except you're actually going to be seeing it again. He's also means. I'm basically taking advantage effects shop and i'll be doing some t shirts for this particular podcast. Also you can start seeing the blogging coming back on and you're going to be seeing a lot more plugged into the patriots page. Let me put a pin in that one. Too humid awesome easy. That you're going to be starting to see the flash reefs a lot more often as well know these are the cube minute things basically were putting out every day on top of that. You're also going to be seen little about another podcast. I started way back. Lynn called waffle house. Could black basically better community through or better yet veteran community through prep. The vichy idea is to look at. What would happen if you could you do and propping but instead of looking at is just a person or even a family. What would happen if you actually get a group of people who are actually in a suburbs situation and see if they could team up and what they could do. And i think if you're doing a post apocalypse this situation and you're prepping for it. I think if a couple of houses together you have a totally awesome situation and so basically. I'm looking into tactic. Strategy has set all that up having a little bit of fun with it. D- consequence you about why it's called waffle house code black israel a really bad joke Basically back in two thousand eleven theed then person the head of the federal emergency management agency. Fema was looking for some sort of informal metric basically. He wanted to be she. They have a way of looking at community in being able to tell how long the group is gonna. How long have you had to be there. And he knows it. Certain companies certain agencies in that kennedy basically be a little bit better be able to look at those businesses until how community is doing..
"colon" Discussed on Webcomics Reviews And Interviews
"More accurately. had. The little chemo is she. We start dealing with cancer especially when rin hopefully because it was so light. My case lacy i was only stage to this means that was pretty much localized and we get pretty much all of it. Once fell swoop however they still wanted me to undergo chemo and radiation already. Basically make sure this of course meant that well. We had to go through a couple of weeks of radiation which he your five weeks exactly of radiation twenty five days go figure. We're basically go into a table. This zap it and twenty minutes later. I'd be on my way mary way. In other south. I was lucky..
"colon" Discussed on Webcomics Reviews And Interviews
"It was weird turns out it was just basically a physical therapy guy leading around could not look at the guy seriously. For the next couple of days at any rate discourse meant that eventually i graduated from going from the one unit to basically was specifically for people going through the same thing i was or other were basically needed intensive care and wasn't exactly an icu. Basically reportedly conscious needed the care. But you didn't exactly get couldn't exactly put you in a regular room so let's just say with the end of the week. I was very happy to be put into a regular room. Even though that took a couple of days beginning used is well. Like i said there was still a little bit of this. Who's nations going on. Nothing major is point but you know you never wanted to create. A person. Go to hallucinations. Not a good thing. At any rate with specially mean is that for a couple of data was basically out. How actually changed the cloth bag at this point. I mean the showing me a couple of times but this time we actually got seriously actually learning how to do it and yeah classmate bag is not a fun thing. Basically this means. I'm going to bathroom a little bit more often as arm. I'm a little bit nastier to deal with donnelley. Because he basically have a that. You have to empty beach. Have the timing down perfect or you get stuff all over the place and is just not really pleasant situation on top of this. If you don't put the classic bag on self the first time a yeah. I actually had nurse come into. The house actually showed me how to do this first couple of times so by the first couple of weeks or so. Y'all still trying to get it down issues. The class bag is an entirely new level responsibility. And you have to watch it because if you miss it once and it over fills while we're pointed out that this you've got all the stuff going on you basically have inside going all over your skin. I'm not really sure if this counselor beauty treatment or.
"colon" Discussed on Webcomics Reviews And Interviews
"Last time i've been at the hospital. I point i join exactly duke. Tear copy solid got was water. The broth the jello ended the next morning. We went into surgery scheduled for the next couple of days. Like you said could meet all basically you as bishop drugs Food or nutrients into an idea was my system. Yeah all sorts of wonderful miss right. I have all the ice chips. I want and yeah took advantage of that one. Unfortunately that apparently also help keep up the juices in the system what is visually translates. Down to between the pain relief. That was getting through the iv. While here's a fun fact for the day she warriors nowhere to go on a vision quest have to go for a date. Cleansing ritual cleansing ritual. They basically you see all sorts of visions. Yep this means basically shove you into a cave closed off and you don't get food for the next four days. Yeah you pretty much. she would. This one's going top of that because the colostomy bag. I was starting to develop a series of sleeping make sense when you have a cost. Me bag debasing is. Is that basically all that stuff that normally we'd go to your system stops its bag. The problem is that i knew the dag. Ub she's not really into regulating you're more accurately monitoring it as to basically to overfill as wins. A classmate bag feels. It's not nice because you've got you've got basically Message just went all over your lay and your lower abdomen. Not pretty not nice. And because of that. I'd be really quickly developed a fear of sleeping. You know straight up geds you sleep for too long. The bag fills up and it explodes. Not a good thing. So yeah this meant that Overcautious three or four days. I had no food almost no sleep in yeah house getting pain relief through i was asking nutrients through an iv here is we. Were doing basically drugs in my systems. See this net. We start seeing all sorts of things and well. i think established. I'm not exactly one of the least creative people in the universe. This of course method. All sorts of things became parents. You need very quickly. And he got all sorts of weird ami straight up. The hospital room was also charging leaders and deputies progressed more. We'd showed up and he became a little bit more shelby senior charles which was observing in of itself. This also meant that at one point. I honestly thought bishops into a version of the universe was nothing but repeating gifts. That's not exactly one of the most pleasant Really creative don't give me ross. But we seen universities three or four france at a time. It can get really weird really quick ami at one point i thought he broke the universe because i thought it recognizes. The place i was looking at was from a toy and yeah. Let's just suffice to say that. I have definitely respect for the whole. We see who's nations and tv that look absolutely nothing. Like reality and people are fooled by them. Anyway you're going. How the heck in that happen. Yeah i definitely appreciate that a lot more now so this went on for a couple of days until basically the juice include out of my system and i was finally cleared to actually eat. There was there to pretty much liquid diet but then he was actually allowed to actually and once that happened of the host. Nations of course subsided. Thank goodness exactly at one point. I was actually being led around neighborhood looking for evil..
"colon" Discussed on Webcomics Reviews And Interviews
"Game she'll host a web contribution of us tonight. It's whereas my colon to sit back relaxing this to geeky begin as a lot of people figured out i haven't been doing whole podcasting or blogging for the last couple of months and yeah there's one heck of a good reason for it and well. It hasn't exactly been front as you can imagine. The yield is back november. I was diagnosed with stage. Two colon cancer. Not all major nasty Just a little bit unnerving so this of course meant we had to go through. All the rigmarole michigan michel testing me. Sure i was good to go and and actually schedule the operation itself. Let's say january twelfth under the knife and had seen in the hospital who Or so while it was there it was sort of interesting. The operation yourself was a success. They removed eighteen inches of colon and install the colostomy bag. That's been all sorts of fun but we're going to put a pin in that same. The fun part was a while it was there. Well there were one or two minor complications. This complication is out for some reason. My stomach is filled with a lot of gastric juice. This of course meant that they basically had to get rid of all that use any way you it was basically well for many. This of course meant the to patti to go through the nose throat in the stomach and of course that point start sectioning wherever juicy could find yet that wasn't funny calendar a basically nurse showed me to ask you. I basically told me to start goping when felt the pressure girl. And the hey. Y'all deviated septum. Before i can ask you that. He is pretty much goping to this. Went on for a couple of days. Only problem is is that when you have a tube down your throat. You can't eat what you think about. That mean. the problem is that before a gun into the surgery. The only meal. I had was what they call meal in. American hospitals is basically means you get a cup of broth additional jello.
"colon" Discussed on KQED Radio
"But you can't be blinded and you need to be wary of what could go wrong and where the costs are and the peril of our actions. So when you think about people who deferred to things happen for a reason, people who Who hand that back to someone in a bad place like Kate, who has stage four colon cancer. What's your response? I just watched my brother leave the world with colon cancer. You know, Harry, thank you. Been thinking about this for a couple of years is In some sense, That's the question of life, which is What's the reason I'm here? And why do I go when I have so many precious relationships and things to do in the world? And I know you've thought a lot about this. Kelly like When we asked that question was the reason for this the end of life for This disease. We get to the rial essential inquiry, right? It gets us to like why my Here and that in our own what William James really encourage us and it's a great tradition in American thought of find out the answer on your own, you know, and you will arrive at your philosophy of life. But I worry about when we turn over the answers to other people and to institutions as a lot of people have Yes. So when you say things happen for a reason, it can almost feel like You're adapting a posture of passivity. I agree. I agree. And and you know, that is a deep worry that we handed over Teo ideologues or two institutions that provide answers, which is ah, deep tendency. The other thing that that phrase everything happens for a reason. Denies us. The opportunity to think about is is that well, you know, parts of life are really complicated and chaotic and unfair and unfair and unpredictable. And that's part of the game, too. There's a lot of science that says, you know, as I encountered grappling with my own brother's passing is which was unfair and he was way too young is We have to face that stuff squarely, too, and not just handed off. What was your brother's name? Ralph? It's for you off. Thanks, Doctor. Thank you. Kelly took a lot of notes during that conversation. Here's what I jot it down. Pain comes to everybody. All our specialness. All the particularities of our lives. Don't exempt us from suffering, and that should make us much nicer to each other. When tragedy hit someone you love better to listen more and talk less. May we count ourselves lucky If we have only had one belly button. There's no cure to being human Kakarrot E is the theater of life..
"colon" Discussed on Thrive Bites
"Invasive type of screening options for patients. So you know there are stool based tasks that look for microscopic amounts of blood in the stool most recently, one of the newer tests not only looks for blood, but it also looks for. Certain proteins or parts of DNA that are shed by large high-risk polyps and colon cancer, and so if any one of those things is identified, it kind of flags it as a positive. So, those are options for people that are less invasive than a colonoscopy. But let's say if you choose the the the the stool test route, the immune, a chemical stool test route whether it's simply looking for blood in the stool you're looking at needing to repeat that test every single year if we're talking about the other tests, the that incorporates the the stool DNA which is known as Cola guard Then if it's negative, you would need to repeat that in three years. So it really depends on. What type of test you're doing which will determine the the timing of your next? Screening. So, let's say you have a patient for example that would opt for the less invasive you stole tests right like could they go for you? That screening period from fifty, the seventy five for example, just on the stool tests or would you recommend like? Hey, you know I think it might be a good idea. We throw in scope you know somewhere in there like could they go theoretically from fifty to seventy five without having to do A scope, would you recommend that if it's someone who is average risk without any symptoms than that is an option for them to to only have to do annual stool tests, but it's really important I emphasize the importance of this if someone decides to go that route, it's really important not to miss not to prolong the the test, the duration between tests. It's very important that every single year that that tests get done. yeah, and we can be so busy in our lives that we can put it off for forget about it. So but what's the importance of emphasizing these choices? Is that many options rain and we have? Enough knowledge and experience and data. You know to be able to say like, Hey, you know this works you know but we just have to educate the patients educate and reinforce that relationship between patients in healthcare provider to be able to say like, Hey, here's your options. Let's get this done. You know in review their history. Which is a nice segment to you know as we close out like what are the things that you would recommend like looking out for like what are the signs and symptoms we talk about this in the beginning but like you know, what are what are things like you know someone was curious like? I am really distraught with you know Chadwick Wolfson's death. You know I know a lot of people that had colon cancer like how can I? What are some things I need to look forward to be like, Hey, you know this is a red flag I need to go see my doctor for things to ask them when they see them. So it's yeah, I'm glad you kind of brought us back to. To the the different symptoms that people should be looking for. You know you know typically when we're talking about colon cancer screening were thinking of someone who's completely symptomatic right someone who based on their age and their family history requires a screening. But when we deal with a systems alarm symptoms that require a diagnostic evaluation that's completely different. So you know for heat for especially the young. Population under fifty. It's really important that if anyone is having rectal bleeding, please don't attribute it to just hemorrhoids. It's very, very important to have that evaluated by a gastroenterologist. Even your primary care doctor start the conversation. Let him know how often that the bleeding you're seeing the bleeding it's really important to to be mindful of maybe changes in in your bowel habits whether. Regular let's say with with not having destroyed and all of a sudden you know you're you're going several days without a bowel movement it's not getting any better. You try to modify your diet. Don't wait months and months to let someone know about that. It's really important that you start that conversation. With your with your primary doctor other healthcare provider yeah. I'm so glad that you brought that up because a lot of people you know from my experience working with these patients is they attribute to hemorrhoids basically it's like, oh I just ate a bag of you know flaming hot cheetos and you know it's bleeding and I haven't pooped in a few days and those are just attributed to that. Young and older and and I'm just like, no any type of blood you know we gotta make sure that you know we. Do our due diligence and follow through like you said. So you can't over overstate this enough on really really glad that you brought that up. So. Absolutely, and especially now that we're seeing this the slow rise incidents and younger people know in the past, we would just say you know less likely anything dangerous anything significant. Probably hemorrhoids work on your fiber for several months and let us know but. It's really hard for someone to just attribute the that rectal bleeding to simple hemorrhoids. So it really is important that people. Get out talk to your doctors listened to your body's and and really kind of start that conversation. Yeah. Yeah. Definitely and so you know as much as we love Chadwick Bozeman how much you brought to the world I would hate to. See other people not actually talk about this and go to their doctor and and and start that conversation. So Tom, thank you so much for being on the show today I, really appreciate you taking the time and sharing your expertise on any follow up. You know a finishing thoughts on you know to give to the audience. Well. Thank you very much for the opportunity? It's it's always a pleasure. It's always great talking to you Colin. I'm really excited for what you're doing and you know the audience you're trying to reach. I think. As. Far as any last minute thoughts, really my suggestion is just to emphasize that colon cancer is a big problem here in the United States it's a very common problem and it's very lethal if caught Leo. So really start that conversation listened to your body's if something's not right if you're having abdominal pain, erectile bleeding or changes in your all habits just and it's not going away after a few weeks. It's really important that you reach out and. Medical. Attention. So yeah. Yeah. Yeah definitely. Yeah. Thank you. Again for those lasts last thoughts. Guys again you know this is a special episode. Forthright Bites on please as much fun and conversational. We tend to get in the previous episodes in over time you know the information comes across says, you know we want you to be well, you know we want your family to be well, you know these are tough times were in the together and but don't. I. Don't want to overstate You know see your doctor and see your healthcare provider and get checked health is wealth thin I always emphasize health is priority. So thank you again, guys this has been another episode three bites. If you'd like this, you know please subscribe and follow on if you feel like this is. Of importance to someone else please share this as well, and we will see you on the next episode. Thank you, everyone. Hey, guys. That was another episode three bites. If you like that episode, please describe and follow for new episodes and don't forget to rate us on apple podcasts..
"colon" Discussed on Thrive Bites
"We're in September. We're in the in the pandemic. What I what I found you know as we talked about, you know the past slash few months. We did UH during we're in season three and season at the season two when the pandemic hit I started highlighting a lot of covid related like when I started a wellness series with that and then throw it over time. You know we just heard a lot of health disparities. The reason why we're being making you know we're talking about the stats is because you know people of Color Black and browns and you know they are disproportionately affected. With colon cancer. But with like Diabetes Heart Disease you know all these different things and I don't know Tom in relation to colon cancer. Why people of color are more but in terms of other disease processes, you know you have health access contributes to it. You have poor quality diet contributes to it and you know just so many different reasons and it's just it really sucks. You know and this this been hitting the news over and over and over again and you know we need to, we need to work hard to kind of you know not. Blacks, but like across the board be, would it help as many people as possible? So I don't know from a coin transit perspective like. Is there a reason why in religious say like you know y you know there are affected absolutely the whole goal is to raise awareness and. That's a great. We. Really don't understand why the there's this such a disparity within. The different races however we assume at this point that it has something to do with the socioeconomic status and their access to health care as you mentioned. As, well, as access.
"colon" Discussed on KTLK 1130 AM
"With colon cancer. He was 43 merger, Jordan and this is Fox News from the Cremation Society of Minnesota Weather Center. A beautiful day today with lots of sunshine. Some clouds in the afternoon and behind the upper seventies showers and storms developing tonight Low near 60, then clearing out Monday afternoon high 72 I meteorologist Mace Michael's on Twin Cities News, Doc Am 11 30 currently 57 degrees I. Heart radio is the number one Choice for music, radio and podcasts. All in one. No one makes it easier to hear everything you love in one free act. It's alright here. My favorite radio station. It's every song that I've hit that thumb up button thing That's a perfect next. My favorite song. I like listening to my station back home, So I feel like I'm going somewhere is the only way I get a vacation I heard has it all. If you're not one of the tens of millions who have the APP, download I heart radio for free today and start listening. Justice. True Information and entertainment 86 Twin Cities News Talk Am 11 31 3.5. Thiss program has been pre recorded. Greetings, Mr Mrs Middle America and all the ships at sea Coast to coast Am this.
"colon" Discussed on 710 WOR
"This past year she dropped a colon cancer in the C. compute a mass of the cecum shed some lymph nodes involved at some symptoms should a massive starting mass and some bleeding and some in the media and she refused all the surgery refused all the chemotherapy says this terrible fear of anesthesia and this fear of surgery and just the refusal to go in the hospital and she came to me with his colon cancer the cecum part of the colon where the large file the small bowel meat and she chose our treatment and we treated I talked about all the options she was very eager says such good experiences with the kidney cancer when our surgeons twenty years ago she had to remove the kidney well obviously she live twenty more years doing well cancer free in remission with their two kidneys like god intended and now she intends to be treated to those seek the sick colon cancer and Richard last year and she came for the first follow up and got a skin and you can already see the cancer mission the masses already shrunken by eighty percent she's in remission she's moving bile she's had no blood transfusions she's doing great no chemo no cutting those surgery for her she co colon cancer treatment takes minutes she lays down in the frame we make a mold around the body it's all old phone there's no claustrophobia there's no cutting there's no pain or stolen decisions we send an invisible beams from thousands of angles to attack this seco colon cancer and she is so pleased and she's so please of I'm so pleased for her this mass is already shrunken down this is the work that we do.
"colon" Discussed on Mayo Clinic Talks
"Do we know how often polyps are missed? I imagined musty tend on the size and the degree of flatness of them. But what do we know about that? We don't we don't really know there are some sobering statistics though, that can kind of give us a sense of the an estimate of the magnitude of the problem. Anywhere from about three and a half to in some series as highest thirteen percent of all colon. Cancers are diagnosed in patients who reportedly had a normal screening colonoscopy less than ten years ago. So that's that. That's one starting point. We also know that there is tremendous variation among individual colonoscopy, providers at their rates of finding these lesions in the colon famous series out of Indiana University suggested that there may be as much as eighteen fold difference between the top detector in their program and the bottom detector and their program. So that gives you some sense of the spectrum. Interesting out. What do we do with patients who are on chronic adequate, relation say, with or friend, or one of the newer products? And we'd know they've had polyps in the past. And so we're expecting some polyp or sections. Can they remain on the antiquated? We need to bridge them. Excellent question in one, we encounter in practice virtually every day for the most part, our, our management of patients when when we're pursuing to me removal of Apollo were increasingly trying to lean towards the use of cold methods. Meaning those that do not require electric, Audrey to be placed through a snare or other device to actually remove the polyp, and we're increasingly reserving the that, that approach for lesions that are larger typically nine ten or, or, or greater millimeters in diameter or ones that have a, a large broad base stock where there may be a feeding vessel. So we're increasingly trying to use cold approaches to try to prevent post polyp to me bleeding, and we would generally say that for a patient coming in for what we think would be a low risk procedure. A diagnostic coal NAS copy with biopsies, for instance, an upper endoscopy with biopsies we generally as long as patients on medicines, like warford or in the therapeutic range, we would actually not stop them. We are, are traditionally not stopping Plavix, or, or the newer, thrombin inhibitors, either unless we end -ticipant that there's going to be a high risk intervention. So dilating stricture using a needle knife, or a, Kanye leading, the, the Bill airy tree placing a peg tube and then the use of hot techniques for polyps to me. Those would be good indications to have the patient off their medicine during the time of the procedure. And there we'd tipping. Cly insist on an I in our of one and a half or less struck about the current available screening tests. When I first started practice, basically, if we were gonna screened for colon cancer, we did a rigid practice copy examine a barium enema don't do those anymore, but what adequate tester out there right now. So currently the endorsed methods where there's fairly broad consensus in guidelines colon. Aw, Skippy is, is still probably the most commonly used screening method in the United States. Fecal immuno chemical testing, which is a newer method of detecting. Occult blood, flexible sigmoidoscopy is still endorsed, but probably only visualizing about half the colon. And so has some drawbacks there rigid proctology copy has gone, and berry is, is going. There are now increasingly few people that. Can interpret that. And it's, it's never been a particularly sensitive test, the newer, modalities like CT colon. Aw, graffiti are our endorsed, but maybe difficult to get covered, and then probably the newest test is the, the, the multi target stool, DNA test, which is also available and broadly, covered. Let's talk about that test who is a candidate for using the DNA based, fecal, fecal test short presently, the, the FDA labeling is approves the use of the test for average risk patients. So, you know, we talked earlier about those with family history. So those people who have first degree relatives with diagnosis of colon cancer in their fifties or younger, or who have advanced adenomas in young relatives. Probably would not be good candidates. Those genetic syndromes, and inflammatory bowel disease patients that we talked about earlier would would not be good. Good candidates. Or if you were personally known to have had prior polyps, especially advanced at enormous that, that would also be an off label use of that test if it were performed. So in general, it's the big the big basket of everybody else. And in particular, the hope with introducing that test into an already crowded field is that as you mentioned earlier, we try to encourage those one in three adults in the United States who are not participating in regular screening to, to come in from the cold, if you will that one in three number comes from survey data, if you actually do chart review and figure out whether or not people actually had the tests that they're reporting they head in the surveys. The answer comes down to probably one in two or not getting screened. I've had this happened with one of my patients where I did the fecal based test, and it came back positive at colonoscopy was negative. What do I do with that patient? Great question. One were asked every day. Keep in mind that the, the multi targets tool DNA test was designed to have a false positive rate of ten percent. And that was calculated from people who had completely normal structural colon. Aw skippy. Exams in a very large study prior to the pivotal trial that was conducted for FDA review that number probably is holding up in, in routine clinical practice. So there will be a substantial number of people now that over two million people have used that test who will be in the same position as the patient, you describe having a positive stool DNA test report. But a negative colonoscopy, the first thing that we need to. Do in that situation is to look at the colonoscopy report carefully is their clear documentation of intimation of the seek them with photograph, the appendices orifice or intimation of the terminal Ilian is there. Good or excellent quality, bowel prep to make sure that the dos campus was able to see everything he needed to or she needed to and was the withdrawal time during the coal NAS copy adequate by definition at least six minutes of inspection of the colon Yukos. In order to be sure that the every chance was offered to see any lesions if all those criteria are met at that point, we do not have any evidence to suggest that there is benefit from additional diagnostic testing that information comes from a couple of sources, we have three published abstracts and published manuscript showing that long term follow up. Of patients with discordant stool DNA and colonoscopy results are no more likely to develop cancer than a person with a negative stool, DNA tests, or Anna, negative colonoscopy, and that came out of chart review and data from both our practice here at mayo, and also from other centers participating in the average risk screening trial that got the test approved, we have a manuscript under review looking at that with a total of more than I believe, more than two hundred apparent false positive exams in comparison to more than a thousand true, negative exams, the rates of cancer, whether that's anywhere in the body, but particularly in, in areas that could exfoliating biomarkers into the GI track such as the lungs or the Pat ability, tree, or the GI Lumine those cancers, not more likely between the two groups and. Both lower than what would be expected from the general population as estimated by the, the seer project. What's in the horizon, we have screening tests for colon cancer? But that's pretty much the only organ, we screened for her a screen test with what else is out there that we may see in the future. Yes. So I think the, the research community is incredibly enthusiastic about blood based screening tests, so the concept, there would be a patient would go in for their annual exam and have a vial of, of blood drawn and some of the same markers that we look for in the stool, DNA tests might also be present in the bloodstream in patients who have an early stage cancer, and that would be one, you know, very exciting approach the big challenge with this so-called liquid biopsy approach is that we need to know in a human being who could have cancers arising anywhere in their body, where that marker came from, and that's a, a major point of emphasis in, in our laboratory to try to develop liquid biopsy screening tests for common diseases, such as colon cancer, but also to be able to. Detect multiple cancers at the same time, which would allow us to screen for diseases that we currently don't due to their lower relative incidents in the population. An important example, there would be pancreatic cancer, which will become more fatal than colon cancer, very soon, but it's not screened for in the general population because it's quote unquote, too rare. The other application for liquid. Biopsy type testing would be in diseases that predispose to cancer, where patients again or in a surveillance pathway, one particular example, where there's a lot of research interest right now is in the detection of Pata cellular cancer in patients with psoriasis. For instance, our current surveillance tools ultrasound, alpha beta protein, probably only about sixty three percent sensitive for curable stage, h c c the Pata cellular carcinoma a liquid biopsy test may be a big advantage over that performance. So that's I in development as we speak finally one big question I have to ask, and I don't know if you've probably like an answer to this, but why can't we get a prep that tastes decent at probably the most common thing that people are reluctant to have colon cancer screening? I wish we could have. Something that tasted a little better, I think that's universally in demand. We do have, you know multiple new choices to us. There are..
"colon" Discussed on Mayo Clinic Talks
"I'm your host Daryl Cheka, a general internist at mayo clinic in Rochester, Minnesota colon. Cancer is the second leading cancer killer in men and women in the United States. One in twenty will develop colon cancer during their lifetime, and it's predicted that over one hundred forty thousand new cases will be found in two thousand nineteen colon cancer screening is affected and colon. Cancer is preventable. According to the American Cancer Society colon cancer, incidence has declined as a result of screening, yet it's estimated that one in three adults from age, fifty to seventy five years have never had screening for colon cancer. Today's topic is colon cancer screening in our guest is Dr John Kissel, a guest Renner allergist add male clinic in Rochester. Minnesota, welcome John Darrow. Thank you for having me. Well, let's start. By talking about the patients who should be screened for colon cancer who when, when should this start happening? So there is broad agreement and endorsement by multiple guidelines that virtually all adults in the United States, who are at average risk for colorectal cancer should start screening at age fifty and that recommendation is supported by guidelines from the United States preventive services task force, the multi society task force for colorectal cancer screening, which includes the American gastroenterology association and the American college of gastroenterology, there are guidelines were issued about a year ago from the American Cancer Society that suggested that based on some modeling studies, and computer simulation, that there would be benefit to starting screening as early as age forty five even in the general population that recommendation has been met with some con. Traversee. I think the benefits are clear, but there may be substantial additional costs and there are some risks associated with screening. And so there's been a general call to develop evidence in support of changing or keeping the current guideline. There are some suggestions from, from other societies that we could start screening African Americans as early as age forty five but in general, I think there's broad consensus on age fifty patients who are younger than fifty and interested in starting screening. Early should talk with their doctor. And they should also probably talk with their insurance company to make sure that, that test would get covered. So that's the recommendations for average risk individuals. How about those who may have a family history of colon cancer, or a family history of colon polyps, do they need to have different recommendations? Yes. Now the evidence supporting those recommendations is. Is is, is low quality, but and there, there are recommendations from guidelines, especially the multi society, task force document from 2017 that suggests that patients who have a first degree relative with colorectal cancer, who was younger than age sixty or younger. When they when they had that diagnosis, or an advanced at enormou- that would be a large polyp one that contained villas or high-grade architecture. So I agree relatives of patients with young, onset colon cancer, or young, onset advanced adenoma, defined by age sixty should start colon cancer screening at age forty or ten years before their relative was diagnosed, whichever comes first, and it's specifically recommended that those individuals be screened with colon. Aw Skippy instead of other screening modalities, and that. They would receive their screening tests more frequently as often as every five years, if you have a first degree relative age, sixty or older with colon cancer or advanced adenoma guidelines have suggested that they start screening at age forty as well. But they can have any of the modalities, and they can be screened at the standard intervals for each of those tests. So no modification to how often so any change in recommendations for those who may have had like a grandparent, who has had colon cancer. No so presently, if, if you don't have a genetic syndrome, and we can talk about that later a second degree relative grandparent, or a first cousin or a an uncle or an aunt. Those individuals would not be believed to be at such increased risk that they would alter their screening pathway. Okay. All right. Well, who's it? Increased risk for getting colon cancer. So there are variety outside of, of family history or rather within family history. There are patients who will be recognized to have a hereditary cancer syndrome. The most common of those is a disease called Lynch syndrome in which patients, lack and one of four enzymes that repairs DNA damage during that, that may occur as part of proof reading errors from normal cell division and Lynch syndrome. Patients can have a very high lifetime risk of colon cancer upwards of seventy percent, depending on the mutation patients with familial ad Nomex polyposis. They will form literally hundreds if not thousands of polyps that will carpet, their coal, and during their teenager early adult years and they have virtually one hundred percent lifetime risk of colon cancer. Rare diseases, such as juvenile polyposis or point Yeager 's these are the syndrome it cancers. And oftentimes those are picked up by a very careful and detailed family history. Those are for the most part, autosomal dominant diseases, where you start recognizing not just a first degree relative. Like, you know, dad had colon cancer, but dad's dad had colon cancer or other cancers occurring in women such as those of the, the, the guy neca logic tracked would be a red flag for for provider to consider Lynch, syndrome, or other hereditary disorders. We are increasingly when we find a person who has colon cancer. It's also been recommended by USPS Tf that we test that tumor for either protein expression or DNA proof proofreading errors that would suggest the presence or absence of Lynch. Syndrome, and now we're increasingly testing all colon cancers that way to identify families who may be missed by the, the older pedigree based methods so outside of those genetic mutations. We also have over a million Americans, the United States who have inflammatory bowel disease Crohn's disease of the colon or all sort of colitis for ten or more years place. Those patients at increased risk, and that's actually, the one of the clinic environments, I practice in commonly, so each of those patients with inflammatory bowel disease, or these hereditary syndromes, fall well, outside of the standard colon cancer screening guidelines, and they now fall into a pathway that we call surveillance because of their increased risk. They're going to have a customized often very intensive and infrequently colonoscopy based testing regimen to try to spot those cancers early or remove high risk polyps. Okay. Well, most of my patients are elderly and. And I need to know. When can I stop colon cancer screening? Is there some general guidelines that absolutely USPS Tf broadly states that screening should be stopped around age, seventy five unless there are extenuating circumstances? There are also models that have been conducted that, that try to demonstrate where a number needed to screen and a number needed to harm intersect. Meaning winter, we actually doing our patients disservice by performing screening abroad rule of thumb for an older patient would be that if they had co morbidity that you thought would would reasonably shorten their life span that you should be thinking about that. And, and typically a rule of thumb for a healthy patient would be deciduous, have at least ten years of very high quality, high functioning life. So, you know, I think as we start to have conversations with patients who have COPD or heart failure, poorly, controlled diabetes, chronic kidney disease. It's important for, for people to understand that the colon cancer screening starts to carry increase risks both for sedation. And also the procedure itself. I've had patients look at me when I have this conversation and say, but are you canal condemning me to, to die of colon cancer? And the answer is no, I'm, I'm trying to avoid harming you with with screening test. That could ultimately result in an invasive exam, or well, the dilemma, I often have is a patient, who has had a history of colon polyps at minutes, polyps with the each colon us copy, and they're now getting into their eighties. Do I continue doing colonoscopy is and this despite their advanced age? But given the fact that they've had polyps I think, again, that needs to be an individualized conversation with the patients and again, their age, especially their medical coolmore biddies more so than than a numerical value for age begin to dominate the conversation. What do we know about how long it takes for a pile up to actually develop into a malignancy? So, you know, dogmatically we've thought that it takes about ten years for a garden variety polyp to arise from completely normal tissue to get all the way to the point of an invasive cancer. But that is essentially an empirical estimates, and the answer the realistic answers that actually nobody really knows. We are very interested when we're doing colonoscopy at making sure that we're finding large and small polyps because the success rate with, which we find polyps predicts, how likely we are. Prevent cancer. But it's not a one to one relationship for polyps that are smaller than five millimetres diameter, probably five out of every six of those polyps might invalid and go away. So I think advocates of a non invasive screening tests stool based tests are focusing, mainly on, you know, the, the success with which we identify advanced or high risk pre cancers as more likely to contribute to the prevention of the development of cancer over time. Right. Do all Flynn cancers, develop from polyps. We think that they do the question is whether or not, we're actually able to recognize the polyp when we're when we're doing an exam. So we think in general that all lesions will proceed through some form of a dysplasia transformation into what we would call. Athle- Apollo up before proceeding to cancer. But. We'll probably need to talk a little bit about the different types of polyps that can be found. And how likely we are during a screening program to find, and remove those, we traditionally think of polyps as the, the adenoma polyp, which in many persons minds, I would be sort of a mushroom cap or a polyp on a stock. However, we also know that probably a third of colon cancer is a rise from Sarid precursors. The, the sessile serrated polyp or sessile, serrated adenoma, the antiquated name are, are flat, and they don't have a particularly large raise surface, they can often be obscured by poor prep and can be very, very difficult to see as a community. We probably didn't even recognize these until less than a decade ago when. We started reporting them through our, our pathology group and actually started trying to devote attention to training and dos campus to recognizing these lesions. Their present predominantly on the, the right side of the colon for the most part. And they probably account for about a third of all colon cancers. So do do the Cecil pilots have an increased propensity to turn into cancer? Or is it just that they're often missed because they're harder to see? I think it's the latter. I think the time line with which the lesions would progress to cancer is probably similar for conventional adenomas our post Pollock to me, surveillance recommendations are similar in terms of the, the intervals for follow up based on features under the microscope. But I think it's actually the case that we tend to miss these more often it's been shown in large observational studies like the Nici har- paper from the New England Journal in. Twenty fourteen that the majority of cancers that occur between colonoscopy, the so-called interval cancers, actually bear molecular features of the series had pathway, and so that makes the argument that they were missed about hyper plastic polyps. Do they carry any malignant potential? They really don't now hyperplasia polyps. We tend to think of as a rising in the, the rectum or signaled colon. And when you have a pathology report that tells you that you have a hyper plastic Pol up on the right side of the colon. Typically, you know, proximal to the splendid Fleischer that might wanna give you pause, especially if the daas copy report says it was large and the daas COPA spent considerable time wagging it out and have a photographic features that would otherwise support the diagnosis of sessile to polyp. So the, the two may be subject to some inter observer. Disagreement by pathologists and the, the.
"colon" Discussed on Fore Play
"Now, I looked at. It's a colon cancer screening made easy. The only reason I could possibly imagine that Tyler would Email us. This is like do you shove the color guard up your ass or something? I'm I'm confused by the question colour guard cola guard sponsored a was the new sponsor of champion's tour event. I believe this past weekend. Okay. And all his Email said was you guys have to discuss cola guard as the new sponsor of this past weekend champion's tour event on the podcast this week. That's all he wrote, which leads me to believe based off his podcast, the type of listener that we have the type of things that we discuss this thing has to be something you like show is you have to insert it somewhere. I mean, there's just no way. You don't have to own like, it's got a cute name. It's got a very cute mascot. I'm looking at the website right now, they made it like this friendly guy that you shell up your ass. That's like, I don't know. If that's the case. I know nothing about this. No clue. However, there's just like if I'm putting together we don't get that Email for somebody unless something like that has to happen with this thing in this website has all the makings of. Yeah. It's going to be fine. You do this. It's very cute. That means. Something uncomfortable is going to have a hundred percent. And it's it's a what a champions tour sponsor. Oh, you start getting up to that point where they check your colon. Stick a couple fingers up your, but which we're not there yet. Right. No. I don't think. So. Okay. Say forty forty forty. That's not that bad actually, stick older that. So anybody look, I don't know exactly what the deal is. I looked for like two seconds at the, you know at the at the website. And like you said it looked like they're trying to make this fun friendly thing not harmful not a problem, not painful now, just your little buddy. And I guess based off what I saw I think, you know, my my show of the thing, you know, you're it's like when you're a kid, you don't know you collect the DNA through your stool. You gotta go digging through your shit like address apart. Yes. When what's his name sick the rhino?.
"colon" Discussed on Stuff To Blow Your Mind
"Yeah. I, you know, I think I'd run across in mention of him in passing that I don't think I'd ever actually read any of the tales about or even the poems about him. I mean, there's a there's a Yates poem colon comforted. So he's not an obscure character of in Irish myth by any stretch of the imagination, but coup Holon is so cool. How could I have not heard about this? I like the people who study Irish mythology gotta get in touch with Hollywood or something get some movies going. So people know these myths better. Well, yeah, he's quite a figure so colon is a mythological hero that has been described as the Irish achilles. Okay. Or even the Irish incredible hulk because maybe a little closer. Yeah. And if you can probably already get a sense here, we're talking about yet, another mythological killing machine an ancient soldier streaked in gore and honor. So in many respects, he is what you expect from from a mythological hero. You know, he's mighty warrior. He has a sense of nobility, and he's sort of pushed into tragic circumstance. He's tough. He's brave. He's brutal. He meets a tragic end right now. He's the he's a central character in the Wall Street cycle, one of the four great cycles of. Diva Irish myth and the cycle takes place in the first century. See and was written in old and middle Irish he also appears to factor into certain Scottish traditions as well largely Irish. So well, let's let's do the life story of colon. So he wasn't born. And he was born Setanta sultanas has given name Coghlan's more like like Kalo becomes superman. Right. So he's the nephew of the Irish king king Connor and he's the offspring of the union between Connor sister. And the God lug we lug was mentioned in that dramatic reading earlier lug is a member of the two author did on the sort of spiritual. God elf beings of of Irish myth. Okay. So like, it would be so as with the likes of say achilles, and Hercules, we have a hybrid on our hands here part human. In part, divine. And and he certainly looked like a like a half divine creature. He has he has some some unnatural aspects to his appearance that definitely line up with what you might expect from a Demi God what like maybe a few too many of certain body parts. Yes for starters. He's just just unnaturally beautiful. He's a paragon of masculine beauty and strength. Okay. And then he has seven fingers on each hand seven toes on each foot, and then seven pupils in each I seven pupils in each I well that sounds like a paragon of beauty now. Even as a child his exploits made him famous and then king Connor himself ends up bestowing the new name on him colon after he kills the great guard dog the hound of Hollan on being Smith here with his bare hands at a banquet. And so he has to take on this new name as penance. Yeah. Like after he kills the Smiths hound. He I think offers to serve himself as the guard. The Smiths forge. Yeah. And so now he is calling and then, you know, at the end of that dramatic reading he's referred to as the hound. So I'm thinking because he's this paragon, masculine beauty and strength. There's got to be like a trendsetting chemic- thing that people just can't match..