29 Burst results for "Chronic Inflammation"
"chronic inflammation" Discussed on Acupuncture is my Life
"So contact accurate now. The next key indicators huge huge huge huge and this is why you know people think you know acupuncture just shoot pain and that's a key indicator body huge symptom of chronic information for slice chronic inflammatory shortage effect the muscles in joint and spine lot on causes a lot of paints. So when you walk into an acupuncture show seen in acupunctures here at acupuncture my life oldest hurts that hurts. This hurts that hurts life. We know right off the bat. It has a lot to do with information. Diagnosed as it can be a form of damp be syndrome. We would call an acupuncture skew. Cold damp be syndrome but it's damp accumulation. The joint and the key is is not all day. Just come and treat the pain acupunctures so awesome that you have no clue unless you acupuncturist explains to you. Wish they usually do how deep they're going to tweet that paints what is causing spleen and stomach chee deficiency what creating the dampness body allowing it to pocket itself into certain areas of the body. And that's how deep acupuncture get. What's calling for that. What's allowing for that to happen precisely. And we'll treat the roof with branch that being damp speech syndrome damp accumulations joint around spy. The body will start to clear it up on joan socializing thing. Oh you know. I got my knee. Hurt ninjas run off to the hospital and get knee. Replacement surgery on. My hip hurts winter to hospitals. Get hip replacement surgery. No no no no. No no no no no. It doesn't work like that. It's all about voice in most cases treating the route that the grand can cru and sometimes we'll treat the branch which is just a symptoms to support the body to clear the root-cause so in acupuncture we know how to deal with issues. and what. What's the best approach more times enough. Now keep in mind. I never speak in. Absolute terms is nothing in. Life is absolute except yeah. You're going to die. We are better absolute. But i won't be on these. Are these symptoms or signs that you have to pay attention to because some lash. Well what kind do to reduce get rid of chronic inflammation first and foremost seeing acupunctures. She and acupunctures next. Just change your diet. This is why thousands every week more and more window shade numbers listening to the eastern nutrition episode of acupuncture because changing your diet including more plant based diet. We'll really slice show change because now you're increasing levels of fiber getting rid of the cox. The patient solidifying diarrhea good bowel movement. Every day the other is removed processed foods from dice. Get rid of. I find sugars. Trans fat. saturated fat. Removing these tends to decrease inflammation include like more mega. Three fatty acids in your diet. So let's say from fish s life just as an example because that tends to decrease proteins that produce information another quality sleep. I say this so much and many acupunctures. My podcast sleep sleep sleep. A good night's sleep. You can't beat it. You wake up in the morning you feel so good and the first thing on your mind when you wake up after a good night's sleep is thank you acupunctures my life and let me go on one of your social media platforms today to see you're talking about sleep. Sleep equals chronic inflation. As a result of stress other things we've done episodes on porcelain. These things are import. Something to think about slice life definitely shopping to think about. But i'm gonna leave you be and i just wanted to talk about the webinars feedback concerns. How many individuals were unaware. Even those that come to the acupuncture clinic unaware chronic inflammation is to focus more reason why they have certain disorders. Why it's evolved the way which has left him with type two diabetes or some type of immune disorder. Us mission is health is west. But i'll leave you this acupunctures my life what's yours..
"chronic inflammation" Discussed on Acupuncture is my Life
"Have blood panel style. Kit kip blood test on and then contact your acupuncturist or acupunctures. My life as a follower shit with your acupunctures talk to them. You know you results from dr. Let them do their intake. You can even call contact acupunctures. My way i slice it will change your life. Trust them it will but a key indicating you should focus on like constipation default. Because that's a key. Indicator body is dealing with chronic inflammations. Some people.
"chronic inflammation" Discussed on Dr. Jockers Functional Nutrition
"To try them out today. Yes allows powerful carful explanation while tetons from doing body and other creating sailor energy. So let's talk about some of the best foods for helping. Heal the gut and also the foods that you know stephanie. Gophers from the food foods land bright restrict our ability to produce key talents and more inflammation got. Also foods helps us. Yeah so when when patients or people when we talk about what. We are most afraid of in terms of health conditions. The things that you see even the heart disease is the most common. That's not what tops the list. You tend to see cancer and alzheimer's disease. And then you see then you see cardiovascular disease great news. Ketogenic diet helps us to address all of those and so foods that we want to utilize first of all Less food less calories and that's a big stumbling block for people you know. We're moving into holiday season. It can be natural to want to over indulge and we have patterns. We come home. Maybe stress at work or stress with the family or just relaxing. And so it's a comfortable time to eat to eat more calories than we should So one of the nice things about being in ketosis or ketone bodies themselves is that they make us less hungry. It makes this the chiba at all. Every single one of us has thought. I should reduce my calories. I should be better about this and had a failure along the way. And that's because simply get hungry and we were driven to go look for alary so when we have kitchens in our system we are less hungry some birds that help us with that first of all you can take exoti- capetown's but we'll we'll talk about bad abbot some bands that help us with that coconut oils. A great goto. Those medium chain triglycerides are fundamental and our ability to make more a key towns and so we get those from coconut oil. It's a great thing. They start utilizing more of the diet. Whether or talking your protein sake and tablespoon and there in the morning or we're talking about saute some vegetables Giving it more substance giving it more fat can really be useful in terms of helping the gut and one of the things that we're learning. And so of course it goes without saying we need to get out sugary foods. We need to get rid of sugar. We need to get rid of the white flour. If it's white it probably needs to go. Those are going to be things that spike insulin. Those are going to be things that keep you from. Getting in kito says i while we know that it's high fat diet. I never liked to see the vegetables. Go so it's still a nice strong focus on greenlee things Having spinach around throwing some stews or throwing a shake you gotta keep the fighter nutrients and then from there what we're learning. Is that when you do that. This is moving into ketosis. Having a qatada diet is one of the best ways to restore a healthy gut lining in fact. They're even saying that. Some of the data around seizures is not just because of the intake. Fats so when i think of seizures i think of. Where's this happening. It's happening in the brain and the brain is eighty percents that so change the diet to better bats better fats in the brain. This must be how seizures work at or seizure. Control works from the diet and it does impart but we're also learning. Is that diet. Changes bluer in the gut. It produces something called ackerman and that akron has been found to be part of the anti-seizure potential that same achromatopsia creates a thicker lining on your gut creates this mucous lining that helps to protect the gut and buffer. The got making sure that proteins don't come into the body that shouldn't making sure the gut lining is soothed and working well so nutrition moves into our system and so a lot of the benefits of those ketogenic foods like coconut oil. Like good healthy nuts in the diet that can provide healthy fats to us like avocado wonderful source of healthy They're not only changing our fat biochemistry but changing our microbiome and that does a couple of things for us. Changing that microbiome. One way we reduce inflammation in the system and changing those bats also changes the inflammatory load because it works on this little part of the cell and we know the peroxy is an anti inflammatory pathway. This is why you've been taught about fish oils as being anti inflammatory. This wild why we've been taught about something like cla helping metabolism because it's a fat that works on those paroxysms ketogenic diet healthy fats. Also work on those barracks zones to create anti inflammatory fats. In our body anti-inflammatory prostate prostate landon. Which helps our brain helps. Our weight helps our energy. And so when we can incorporate these foods enjoy our diet a very powerful tool to help us with most pathologies out there. Yeah so good. So you're saying let's get these healthy bats the narrow lots of vegetables. Let's keep the carbohydrates so the grains the sugars things like that. Let's keep those out. They spike insulin. Osu wanna keep her insulin down. Low amnesty less often right. And so there's a big a big thing like if you eats once or twice today as opposed to three to five times a day using the same amount of calories. You actually have twenty five to fifty percent less insulin. That's released when you do that. And and there was a big study. That just came out that really confirm the low carbohydrate hypothesis sometimes were taught that the data is back and forth. I think it's a little less back and forth. And sometimes the media would like us to believe really every time they set up a study to try to prove that high fat diets cause you to gain more fat. So that's the bias. They're trying to show that it does that in when you have bias in a study you influence it so even with the influence. It's failed to show that high fat diets are the diets that keep us from releasing insulin. Guess what else keeps us from releasing insulin. Not but he tones. I used to think well the only good key tone is the one we make because it must come from fat cells and so if you're making your cheap then you're breaking down your own fat and that's the benefit that i was wronged. Yes there's benefit to that. Of course that's how we lose weight but exotic key towns helps mimic what our own she toned bodies do when i take some heat towns. I'm going to be less hungry first of all because my body says Food is scarce right now We're hunting we're gathering. Don't disrupt the hunt and the gather with billing more hungry so those kitomura a single to my brain to eat less then..
"chronic inflammation" Discussed on The mindbodygreen Podcast
"Don't have time like let's just be realistic. We don't have time. parents don't have time. i have canned sardines can mackerel and cam salmon. And they could choose whatever they would perform. I'll take that out. i'll put some. i'll just uncanny. I won't even. I mean. I just basically put it on like a salad for them and then i'll give that to them or you just make some olive oil. I know one of mine. Like little raisins and i know it's crazy it. He'll eat that for breakfast. That's great you love like he loves it. Can salmon mixed all boils. Himalayan see south of even raisins and output even throw in some celery. And it's like the easiest quickest fastest breakfast that i can get into their bodies and for me and then i'll put a With the plate of vegetables and fruit and then there are like i mean those are. That's my biggest. That i love but again as parents to have those snack type items also available also. My kids don't feel like they're left out. I always have almond flour crackers or we have cassava flour. Things that we can have like again. There's love taco shells that you can keep in the pantry along with bars and beef jerky stakes are so many things for pantry. Wise that you can do but again those are detroit so my kids don't feel left out but really just focusing on the vegetables acclaimed protein and healthy fats is really really love to start off with and then have the pantry stocked with golden berries and different types of not sincere that they commence net gun and then all inside kids love. Our lives can always start popping matt. So i'm telling it's really when they're empowered of their own bodies and they provide them with things that they need. They can then make those healthy decisions when and there's not. There's no food fighting in my house. I don't say don't do that don't do this. Don't do that. Because i think a lot of negativity that we have around food is the all of them when we keep telling kids that they can't have this. They can't have that we can't have this but not in my house thinking of anything they want and so it really empowers the child. So that's what i liked. Didn't do although snacks and then have the vegetables clean pertinent unhealthy fats. We also have a lot of the simple nells almond flour crocker's. It's a good snack for them or on the go absolutely and then i mean my kids actually are in love with right now. The there's cashew coconut chips. Also that are really great and even that hughes started making these common firecrackers super clean not some vegetables. But it's i love it. And because i have a flour once these things. I have in my house especially burritos burrito wraps cassava flour. Turn those quick meal throw in the coast of the chemicals. Slough throw in some whatever. I have in the protein throw in some salsa. Wrap that up broccoli sprouts at a time. I like to sneak on the Wrap it up. Give it to the kids. I mean it's so easy on so on the overall subjective gut health something else you talk about which i think is really interesting. And i'd love if you could just do a primer for. Everyone is gut associated lymphatic tissue or galt. It's pretty important. So can you give us a primer on galt absolutely so got associated. Lymphocytic tissue is a component of the new cosa associated lymphoid tissue right and that it which works in the immune system to protect the body from invasion and the gut. And there's lots of different. I mean the the gut associated lung tissue actually makes up seventy percent of the immune system by weight and has significant effect in the strength of the immune system as a whole so. There's lots of different pieces. I mean of the associated around product tissue we have the pires patches and the miz tonsil or rings and lymphoid. Tissue that accumulates aides in the in the stomach ms lots of different pieces but the gut association pat. The they're all really important for optimizing your in the like the first line of defense. And that's where they are because we all know that. The gut associated lymphatic tissue. That is all really first line of defense between every anything that comes in and out into our body right and so keeping your microbiome healthy optimizing the foods that you're putting your stress levels. All of these actually optimize their overall immune system because of the house of the immune system that got associated dishes that everything that we talked about to improve inflammation can actually optimize the ability of the immune system specifically house of the immune system that guy associated tissue. I'm curious beyond everything we've discussed. Is there anything specific that we can do to strengthen that tissue. We talked about. So they actually. It's really quote. I know that exercise is one of them. Nature getting out and major exercising. There was actually just a recent study that showed that progressive exercise progressive increases in physical activity can actually generate changes in the intestinal microbiome. That apt optimizes the gut associated among paddock tissue says the ackerman seattle. That was just twenty. Twenty one so it's really new research that we're learning more and more about the things that can increase optimize your micro bayada and that can then influence the associated with adaptation any mentioned nature. There was also a recent study. Essentially your gut microbiome takes a lead from your the microbiome of your surroundings in a positive or a negative way and so spent more time in nature. Probably better for your microbial. Oh absolutely because remember we are. I mean we are part of the earth right. we've been involved to benefit from like the earth a major. But because we've been moving away from that that now is leading to all of these microbial lack of microbial diversity that then is leading to increase of conditions like asthma and autoimmune disorders and food allergies and all of that. So i mean if the nature is really important to optimize over all immune function and something. I loved near book. it was like it. Was it the whole second half of the book. You have all of these home remedies for all sorts of ailments like any possible amen- you could dream of or think of and you had supplements aromatherapy herbs. You name it and you go into great detail in great detail and so in the same way that some people have the staples in in their house. What are the three to five multi-purpose staples when it comes to remedy for ailments that we should just all have in our home absolutely. this is for the basic. I think that we have this fearless start with the supplements right the supplements i that everybody needs to have the help of these of those. Are your omega three right. Vitamin d magnesium. Actually they did a study. Where in twenty twenty. Th they showed that magnesium is one of the most anti inflammatory nutrients at can help them sleep so just optimistic alba pain and can help with so many different obviously part of like a three hundred more than three hundred zero baltimore than three hundred matic functions in the body and then the other thing that i love for supplements as even to work site feel like everybody.
'Weight isn't always within your control': Why some states are prioritizing obesity patients for the COVID-19 vaccine
"State leaders make their own decisions on wind groups or eligible, but many people are not happy about obesity being considered a risk factor that should get early dibs at the vaccine joins us now to talk about this Dr Fatima Cody Stanford, She's an assistant professor of medicine in Massachusetts General Hospital. She's also in obesity, medicine, physician and adults, Adolescence and Children and MGH Wait center. Thanks for joining us tonight, Doctor. Thank you for having me. I guess the first question becomes one of the risk factors for those who are overweight when we're talking about Cove it so it's important for us to recognize that obesity is an actual disease, and I think one of the things that people don't realize is that it's the disease is not just how you look. It's actual, a disease process characterized by a high degree of inflammation. And so when we have that high degree of chronic inflammation associated with obesity, the disease it doesn't play well with the acute inflammation of covert 19. As such patients that have the disease of obesity do have a risk of dying. That's much higher, sometimes 3 to 4 times the likelihood of those that are leaner and wait. So it's important for us to recognize that this is important. We need persons with obesity to be vaccinated. We want them to live. We want them not to need ICU care and be on the ventilator. And that's why I think that this really is a prudent and a really important step for those that have the disease of obesity. Doctor. I want to read a quote from the chairwoman of the Obesity Action Co Elite coalition, who was featured in the USA Today article, she said, Wait isn't always within your control. With that in mind, and what we know about the risk of obesity and Kobe complications is the right move to get obese Americans in this next phase of the vaccine. One thing I'm gonna change I don't want to call people will be so this is a label. Obesity is a disease. And so that language can be highly stigmatizing for my patients that actually have this disease of obesity, but hands down. It's the right move to get patients with obesity vaccinated when we're looking at the vaccines, the fires of modern of particularly we saw that patients with obesity had a similar level of immunity with regards to the vaccines as persons that were leaner and wait status. So if we know that they're dying quicker. We know they're getting sicker and having much more Colton disease processes associated with covert. We need to make sure that they're getting vaccinated. Have you had a chance to talk to any of your patients? What was their response when the news broke that the possibility of them being moved to the next group? They're up to get the vaccine. What was that thought process. What was their feelings about that? There were some that felt you know a little bit guilty that their weight status would cause them a higher likelihood of getting the vaccine sooner than others. But many of my patients were actually very pleased, actually finally be able to get this vaccine so that we can return to some sense of normalcy here in the United States and around the world as we try to navigate these issues with social distancing physical, do, insisting and getting back to work, So I think that it's important to see that there's different camps in terms of what people think. But overall for my patients that have a B C that Aaron care they were very relieved to see that they were moving up in the ranks of the consideration for the vaccine. Alright,
Is Processed Food Making People Angry and Stupid
"Heireann droop wrote here host of the green podcasts. When it comes down to what we're made of so much of it is about food. Food literally builds us brick by brick cell-by-cell that means what we eat provides. The building blocks that make up the entire body which means unfortunately for a lot of people. They're made up of junk. Our poor food choices gravely impact our brain health resulting in behaviors. That leave us. More lonely anxious depressed illness prone and more overweight than ever before my guest on today's minneapolis owed doctors. David and austin pearl mutter and shawn stevenson talked to us about how our health our relationships and even our thinking have been damaged by our western processed food diet. They discuss how our lifestyles and diet. Impact our brain function and our ability to make good choices as well as how we interact and show up for our relationships. Let's listen in starting with my interviews with doctors. David and austin parameter. I want to read a passage from the book. Our are being gravely manipulated resulting in behaviors. That leave us. More lonely anxious depressed distressful illness prone and overweight than ever before. So we talked about those two aspects which is how do we help and support people to actually make these decisions and implement change in their life to achieve to achieve whatever goal that they wanna focus on. But let's start off with what is actually hijacking. Our brand that. It makes it difficult to do. So can you describe the landscape landscape and the state of threats that our brains are under today. Sure we'll start with one of the most important and probably most straightforward of the its food. We need food. We need to eat food to keep going. But what is it that we're putting into our bodies. A recent study showed that sixty eight percent of the foods that people eat and buy in. The store have added sugar. We know sugar isn't really a good thing for us but the question has to be. What is it doing to our thinking. What is it doing to our brains and is the question that i think were now able to answer but we haven't been looking into nearly enough. What is sugar doing to our brains. Will sugar fosters inflammation which listeners know is not good for the body. Chronic inflammation has been implicated in variety of problems. Things like heart disease. Things like alzheimer's disease. What we're understanding now is that inflammation this process that sugar up regulates changes are thinking. So let's let that sink in. It's not that it changes are thinking in the long run. It changes are thinking right now. Inflammation has been shown in several recent trials to bias our decision making towards short-term impulsive thinking so to put that into context if you're eating a diet that increases inflammation you're going to make more short term or decisions like eating diet that increases inflammation choosing the wrong foods to be eating and that transcends just diet it gets into other things if you're somebody who struggles with all nine shopping. Now you have a diet. that increases inflammation. You're going to be picking the short term reward and that means your your shopping. Cart might be filling up online with things that you don't need so again. Food is one of those entry points. It's something that has been made incredibly palatable over the years and while that means it might taste good. We need to appreciate that. It is activating these circuits within our bodies within our brains that are making our decisions more impulsive more short term oriented and in the big picture taking us away from the decisions that will lead us to health and will lead us to happiness and let me add Before we move on from food and because it is It is a very important topic because we recognize that in a simplistic model there to areas of the brain. That are involved in decision. Making the prefrontal cortex which is the more advanced area. If i may and the more primitive if i may amid della and you know there's a balance between the two we tend to With inflammation unfortunately have more input from the primitive and magdala and as such are decisions are not really looking at the future as opposed if we can reconnect to the prefrontal cortex and that is the area of the brain that allows us to participate in a process of thinking of the long term consequences of our actions today s to be more empathetic. It allows us to be more compassionate has to tamp down this sense of us versus them. That comes from the amid bella. So we're trying to reconnect to the prefrontal. Cortex and in a as per our discussion of food and inflammation inflammation absolutely threatens that connection and i have to say that A thought came to me this morning while in the shower some of my best thoughts come to me and shower and having read the new york times this morning they had an interesting article about what's going on in brazil with reference to deforestation the amazon. Not a good thing. I think most people would agree with that but that said what has happened to the thought process around the globe. is influenced by the globalization of the western pro inflammatory diet. That as this western diet a finds its way to every corner of the globe. It's changing how people across our planet think and behave
Beating Anxiety With Food With Liana Werner-Gray
"Well. Hey guys welcome. Back to the podcast. Today we're gonna talk about anxiety free with food. And we have the author of this great new book liana werner gray. She's a good friend of mine. She's written the earth diet cancer-free with food and now her new release anxiety free with fooding zaidi's such a big issue. There's so many people that are dealing with at especially with everything that's been going on in the world today and definitely a key link between gut health in the foods that were eating and how our brain is handling stress how reactive we are The way that we are processing the things are in our world and sewing. Zayed's is not something that is You know it's not a. It's not an end destination there. There's a lot of hope for a lot of things we can do for it and really starts with our nutrition lifestyle choices that were making so liana. Welcome to the podcast. Thank you so much. Thanks for having me on wolf for sure and again. This is such an important topic. And you know you're a young woman and so anxiety. Obviously all all all genders all demographics steel with anxiety but especially women and would love to hear your story. Yeah so anxiety. Apparently this year the stats have gone up to one in. Three people are really struggling with anxiety versus one in five last year in two thousand and nineteen. Now it's already into two one now. Yes so it's anxieties to skyrocketed and it does affect everyone end a small amount of anxiety to as a stress response is considered healthy. So if something happens to us and we naturally feel that stress. It's the mind in the body's way of saying okay need to have a resolution for this but anxiety that is happening for hours or days days. That is a severe anxiety that we need to be suffering worth of struggling with end. What i discovered was that there are actually some really simple and quick effective ways to clear out anxiety and he'll it especially with focusing on nutrition. Sir i was experiencing heightened amount of anxiety and i was curious as to where it was coming from because i have a lot of faith believe in god and goddess like dart have anxiety costs. All your kids on me. And i was constantly doing that so i was like. I don't think it's coming from from a spiritual reason. And i thought i don't think it's coming from a mental or emotional reason either and i thought this might be purely chemical and it could be a chemistry balanced my brain and so i went and got a blood tests. Done and sure enough isn't in one of the main things that if we're deficient in that we will have anxiety. According to science so short enough. I was deficient in her mega. Three fatty acids and my started taking fish oil supplements Wild fish and then eating more cheese hemp seeds and a matter of days. I could feel the difference. My brain felt more if that's visual. Nfl less scotteri. My nervous system felt more common for chris. I didn't feel more tired. I felt more alert and energize and it was incredible feeling and i thought wow if this is if it's as simple as this and a lotta people are also chemically imbalanced with their physical buddy than i wanna share this answer. I really went down the rabbit hall set of researching putting this book together and found out a lot of other nutritional reasons for the causes of anxiety and then do a lotta research. What foods can help clear out. And then what food. You're actually proven genetic that actually causes anxiety as soon as we put them into a mouse. Yeah it's a really good. Really good intro to this topic. And so we know that fish oil. Epa ya the long chain omega threes really play important role in the brain and also play important role in our inflammatory process. And so you know where people have been told when they have mood disorders that these things are chemical imbalances but the chemical imbalance is really downstream. It's you know it's not. The root cause cause oftentimes has to do with nutrient deficiencies and chronic inflammation. In the brain. We have inflammation in the brain. Were going to be more. Reactive are neurons can be closer to thresholds. they're going to be Firing off from stimuli. That probably probably shouldn't be firing off from right. Which makes them more reactive. And you know makes you have a lot more. Cha challenges just trying to control your emotions and so glad that you're able to figure that out and make a threes are really critical at this. So let's talk about the relationship between the gut and what's happening in the gut and what's happening in the brain. Yeah we'll i know you're a gun expert and i love the work that you do on this and serve all of the studies on anxiety pointed to the gut brain connection and how connected they are and that we have certain gut microbiome fascinating studies. That i found was that people with anxiety have a difference dot microbiome than people who dart have severe anxiety. That was fascinating to me. So then that tells us that we can change our gut microbiome and that will therefore change the anxiety that we experience and then we can also work on the the brain pot a bit and the part of it will reduce that. That's also going to change our gut microbiome so they work hand in hand with each other and so in my book. It's full of recipes and foods that really helped cultivate are very a very healthy gut. Microbiome and healthy gut environment and helped clear out d talks. I'm a huge advocate for detoxing especially people are just new to getting into this then. A detox is totally critical to clean out. That you know the dirty water so to speak dirty water we can fill it out with the clean water so doing a detox to clear out the gut and then start rebuilding it with all the good stuff and that helps out brain sorry much. Their source are connected that gut brain connection.
"chronic inflammation" Discussed on Green Wisdom Health Podcast by Dr. Stephen and Janet Lewis
"Hello and welcome to this week's edition of the green wisdom health show. I'm janet lewis dark lewis and we hope you guys are having a wonderful week so far and we are going to help you out a little more and talk to you about inflammation because as we are having a sedentary lifestyle boringness more of us are becoming inflamed so today's show is how chronic inflammation is related to anxiety amongst other things. And then we'll answer some of your questions you have for us as well. So dr lewis We'd like to know about inflammation you know. Most of us think is just something you live with. Most of us may not even know we are inflamed and some of us don't know what we're doing to 'cause it so can you help sort all of this out for us about. How does that have anything to do with anxiety. How this just sit and still have something to do with inflammation. Why do we care. That's an open ended question There there's a lot of things here and you know they I'm going to try to talk fast. Which is unlike me anyway because always have too much to say I think the the bad news is at time flies and the good news is you're the pilot so you know you can get it done. You can make decisions. That can have a positive impact on you and your family Pours inflammation and sedentary lifestyle. Well one thing. I think is creating a more inflammation being sedentary exist on social media in here and all this Stupidity that's been bounced around. Where if you put the boy sarrazin out there you get attacked for it so style social media go out walkin. Woods at definitely creates.
Leptin Resistance: Causes, Symptoms & Support Strategies
"While hello today. I'm talking about leptin resistance. The major causes the symptoms. They may experience. If you have it and support strategies you can take your body can heal and function at. Its best so when we think about left in it is an incredible hormone and actually comes from our fat cells so years ago we used to think the fat cells or basically just energy reserves but now we actually understand them as part of the endocrine system meaning part of the hormone system and the reason why they produce this hormone leptin also another hormone adiponectin as well as they actually produce multiple hormones but left in is the one that we know the most about and leptin plays a big role in helping regulate bone mass helps activate immune cells. It helps to balance. Dry blood pressure helps regulate thyroid. Hormone controls appetite. Which is what we know it mostly for is its appetite regulatory center But it also helps to Put the brakes on insulin release and it helps to regulate the menstrual cycle. So it's a major hormone very very critical and we start to release leptin when the fat cells start to grow okay. So as we're eating we naturally start to fill up fat cells and then leptons released it goes to the brain part of the brain called the hypothetical miss which is kinda the antenna of our body which is constantly sensing the blood stream and kind of seeing what hormones are there and what it needs to be able to adapt to the environment so when leptin gets released it goes up hypothalamus senses. That leptin is there and it says okay. I'm satisfied satiated. I can turn off insulin release. And now i can turn on a fat burning case now. I can go ahead and burning fat for fuel because the fat cells are filled up. And i can turn off insulin. The problem though is when we're dealing with chronic inflammation can affect our leptin sensitivity in our hypothetical mess and therefore we don't feel satiated and we don't turn off insulin release and we don't we were hungry. Wanna keep eating and we don't burn fat for fuel so the counterpart to leaped in is growling gremlin signals hunger so when our stomach is empty. We release growled. Grr elon goes up to the hypothalamus and tells us i'm hungry. I want to eat so ghrelin. And leptin are basically like on the see-saw they are the opposites. They're antagonists warmer satiated. We've got high amounts of leaped in nats over ranking or gremlin. When we're hungry we've got grown. being released. not much slept in their former hungary k. So that's basically how it works now. Here's how leptin resistance works so lapped in functions turn off appetite while promoting the burning of triglycerides that bloat fat cells as people accumulate excess fat cells. Or you know there another term for them. Is adam sites. Siri active protein. Which is an inflammatory protein is released. So as we start to accumulate Fatter boat. The fat we release c reactive protein that binds to in the blood. It impairs leptons transport across the blood brain barrier and thus prevents leptin in from performing its dual function of breaking down stored body fat and controlling appetite as more fat cells on the body greater amounts of c reactive protein are released binding leptin even more. This is the vicious cycle of leptin. Resistance helps explain why people often get fatter with each passing year. Because if you don't stop this just gets worse and worse and worse because you don't have the natural satiate switch c- continue to eat. You continue to produce more leptin which binds the c reactive protein which which turns on more inflammation in the body. We get more and more inflammation here and we have a major problem there and this is basically how we have the in weight gain cycle so basically we start with a disrupted signal and he can really start anywhere on this circle. But let's start with a disrupted signal so even though we have an abundance of stored fat and leptin. The signal to our brain gets disrupted. Like i was just talking about so the blood brain barrier the c reactive protein bound. The leptin can't cross. It's too big a molecule to cross. So it can't cross so the hypothalamus does not get the signal from leptin them we overeat because we don't get the natural satiate signal and that leads to food cravings and over eating which increases the amount of calories. We're consuming oftentimes sweet foods and foods that are healthy for us we gain weight and then that weight gain increases the amount of being released which therefore increases c reactive protein and we end up with whole body inflammation and leptin resistance and the cycle continues. And so the main causes of leptin resistance are stress and poor sleep chronic inflammation our body and that might be from like gut infections different bio toxic illnesses. Like mold toxicity or lime disease or something along those lines. Something that can drive up inflammation insulin resistance
Digital Tools to Measure Blood Sugar & Metabolic Health with Dr Casey Means
"Well, hey everybody, welcome back to the dr. Jockers functional nutrition podcast and you guys know that one of my favorite topics to talk about is blood sugar insulin and metabolic health and we had a great interview recently with Dodge van Dyckman. We went in depth on that and this is almost like a follow-up to it because we're going to talk about really the personalized approach to really looking at your blood sugar and how it's responding to the foods that you're consuming and so my guess is dr. Casey means she is the chief medical officer at levels and she is a Stanford trained physician again, chief medical officer and co-founder of the metabolic whole company levels, and she's the associate editor of the international Journal of disease reversal and prevention and he can find more information about her at levels health.com and we're going to talk about what the best food. Are for blood sugar management for metabolic health and how that could be variable depending on how your body is responding to the foods that you consume. We're talking about personalized medicine. So dr. Casey that joining us here. Thank you so much for having me. Dr. Jockers. So happy to be here. Well, yes for sure and I've heard of several of your interviews on other podcasts and you really do a great job of explaining how important blood sugar stability is and you know, this this new technology that we have now continuous blood glucose monitoring. And so what I love to do is start with your story and you know how you went from Stamford and trained in in medicine to now kind of branching out into a functional nutrition Integrative Medicine approach. Yeah. Absolutely. So like you mentioned I trained as a medical doctor conventional medicine. I trained at Stamford did my undergrad and Med medical school there and then I went on to become a head and neck surgeon. So I was deep in the surgical birth. Hold for about five years and in my role as a head and neck surgeon, which is really treating the conditions of the like your nose and throat. So an ENT surgeon something I noticed was sort of hitting me back, you know after about five years, like wow pretty much all of the conditions that I'm treating are inflammatory in nature. They're all related in some way to chronic inflammation. So some of the things you think about are like sinus infection, which is inflammation of the sinuses and chronic ear disease, which is inflammation of the eustachian tube the tube that connects the nose to the ear you get, you know inflammation in that tube and you get past building up in the ear, you've got Hashimoto's thyroiditis, which is inflammation of the thyroid you've got things like vocal cord granulomas which are inflammatory masses of the vocal chords and then lots of head and neck cancer, of course, which we know cancer has very much relationship between inflammation. So it was really interesting to me sort of step back and say wow. This is sort of a very common theme between a lot of the conditions that I'm treating and in some way it didn't make total sense wage. That we would be treating those conditions with surgery because chronic inflammation is fundamentally a issue with how our immune system is responding to perceived or real threats in in the environment in our bodies and thoughts were more were learning about how chronic inflammation is in many ways really rooted in our everyday exposures. So what we eat the toxins were exposed to in our food air and water, you know, how much sleep we get the stress in our lives how much or how little exercise were getting our microbiome all of these things have a direct relationship to chronic inflammation. So I'm treating it with this sort of very reactionary invasive more anatomic approach with surgery, you know, there was some sort of missing missing link there and certainly surgeries are really important in beautiful art but phone no other conditions really rooted in chronic inflammation. It kind of got me thinking there might be a better way to approach us. What could we be doing what sort of really personalized dietary and lifestyle interventions really foundational help to really quell bath. Chronic immune response. Well that threat the body is sensing and potentially keep Patients Out of the operating room. You're not going to prevent all surgeries, but I certainly think there's some low-hanging fruit we can do to help minimize the severity of the disease is and hopefully never have to get have them get that really end of the line where they see me in the or going under the knife, which is a really serious serious thing. So that really got me on this journey of trying to understand the root cause of disease and that led me to functional medicine and so I actually stepped away from the operating room got training with Institute for functional medicine and really started thinking of disease a lot differently. I started seeing things much more as symptoms and diseases often being the branches on a very similar true and that tree that we that that sort of route that that connects a lot of seemingly disparate diseases often comes down to things like inflammation and even deeper Inflammation metabolic dysfunction this was talked about so beautifully on your episode recently with dr. Bed big man who is talking about metabolic dysfunction and insulin resistance, but was so interesting is that you know in our country. It's it's not that about 88% of Americans have met have signs of metabolic dysfunction that was shown in a study a couple of years ago from UNC that 88% of adult Americans have at least one biomarker of metabolic dysfunction and metabolic dysfunction and insulin resistance, which are kind of two sides of the same coin really can directly feed into inflammation. So it's all really created and what's sort of hopeful about this is that those are things that are readily modifiable with smart choices in and how we live and what we expose ourselves to so became really interested in that and and really this system the network biology movement, which is really stepping back and saying, you know, we've we've conventionally looked at diseases in in conventional medicine. As isolated silos, you've got depression. You've got obesity. You've got diabetes. You've got prostate cancer. You've got IBS and these are all things that are different and we treat them separately with totally different with medications a totally different mechanisms. But when you step back and you use sort of more advanced research techniques, like whole genome sequencing and proteomics, how can we actually see? What are the molecular links between diseases and you create a web a network a system and that's really the root of systems and network biology. And when you start doing that you see these connections and I think the future of Iraq and its really treating conditions at that level at the connections between diseases cuz when you do that you can you know, hit a lot more birds with one stone that's sort of a negative metaphor, but you know what, I mean, it's it's it's got instead of playing whack-a-mole. You're really you can have multiple various effects with with some single interventions effect that root cause physiology. So my career really moved
"chronic inflammation" Discussed on Dr. Jockers Functional Nutrition
"Triggers. That's one of the great things that you do with the by under virtual nutritionist work with with your clients. Now, going beyond nutrition, what are some of the other major factors you're seeing? Well stress in slate are two other things that are really talked a lot about with my clients nutrition stress in sleep to me are equal as far as if you're not sleeping well than your diet can be perfect. Not going to feel well and stresses the same way certain chronic stress I causes inflammation by modulating key inflammatory pathways. It also induces behaviors that lead to inflammation light poor eating habits in lack of exercise and drinking alcohol and things like at. A I've seen chronic inflammation can lead to things like depression and overlapping diseases because they're linked to that pro inflammatory released do chronic stress. Stress Affect your digestive. System. Of had a lot of clients tell me when they get stressed they'll have IBS type symptoms for example, or have to bring to the restroom and. That's because your body is inviter flight in a lot of us are walking around in fight or flight sympathetic nervous system, and it can be over activated where you're stuck in sympathetic for too long. So the Para sympathetic is your rest and digest nervous system and when you're in fighter fights of pathetic mode, then the rest in digest is compromised held the body. Leads can lead the bite all these digestive issues that I was talking about. So it's really important to dress dress deep breathing. One of my favorite ways the just getting out for walk in nature. It's amazing what that can do for the body you get the vitamin D for the sunlight you fresh air you're getting exercise just as simple walks trying to do that. Every day is great. In in power. -tising sleep. Sleep is really critical. I have. A lot of my clients are trying to get by on five to six hours of sleep and they wonder why they don't feel well each day and most people can't do that like there's a few people who may be able to do that for most people that's going to catch up with you. I've seen it over and over with people and when you have poor sleep habits in your deficiency late in, you're likely to have blood sugar imbalances in those blood sugar imbalances or another cause of chronic. Inflammatory responses. So it also increases cortisol. Asleep deficiencies are linked to obesity diabetes high blood pressure on a different conditions. So making sure you're in bed by ten PM, every night is one of my top tips for sleep. You having a consistent bedtime schedule where you're getting him bad turning the phone off I can't tell you how many clients late with their phone next to their head and tell them put it on airplane mode. Put it in the bathroom your alarm will go off on airplane mode. Music for alarm. So by is didn't shoes but it on airplane mode, you don't want those ems all night long bright their next year brain. And then using blackout curtains or sleep mask is most people sleep better in complete darkness away temperature very cool. Room can be helpful in avoiding artificial lightly get off your device at night. Don't sit there on your device still midnight in the wondering again obviously, you won't be able to fall asleep because it just keeps your brain going. So just different strategies, but really trying to broher Thais, lead into everything you can to manage stress. We're all have stressed especially in the world we're living as so you just got to bake whatever steps you can reduce the stress in your life and make it a priority because it is essential for your health. Yeah hundred percent agree with that and so when I think about sleep, I, think about detoxifying and draining the brain in. So just like you talked about sleep disorders associated with metabolic disease, diabetes, blood, sugar issues, weight loss resistance also very much associated with dementia Alzheimer's Parkinson's early degenerative conditions because you've got to basically take the trash out of the brain. That's what happens when you're sleeping. So very, very important prioritize at really won't heal as regenerating. So very critical, and then when we're stressed especially for stress Mer eating, you know tell people all the time the concept of fast food, not just the food quality there but also the idea of it. Really not congruent health because when were on the go or stressed, we are shunting blood flow away from our digestive organs we. Were in fighter flight. So all the blinds coming to the muscles extremities. When we take some deep breaths or you know like in our house will pray before we eat that act of gratitude and deep breathing tells the body. Okay. Let's turn on the Vegas nerve or the Para sympathetic nervous system start activating stomach acid bile flow pancreatic enzymes can really digest this food effectively we don't do that for eating on the go. We're not going to get that digestive juice release and actually eating the food even if it's healthy food can cause a lot more. In, the body because we're not digesting it properly and it's even more I, mean food food quality super important but also your ability to process and digest it maybe even more important than than even quality. So you WANNA POWER WANNA really protect those mealtimes I. think that's very important. Now what are some US mother things I mean talked about stress sleep nutrition off. Great. Thanks for people to get started with good foundation. What are some other areas that need to be addressed? Especially, let's say somebody's done a lot of these things still struggling. Often, they'll have some type of underlying infection like you're managing a little bit of Goad Konig infections. I see that a lot with my clients we have some great testing so we can really identifying address actual infection at the prison has that there is very commensal bacteria viruses parasites have lana clients with funnel infections. Candida. So they escape remains system, Bob, modulating the immune response. Instead, this can cause inflammation. So it's really important to address this chronic infections. Yeah for sure. So you have things like, for example, H. Pylori that is a normal inhabitant of gut microbiome, but when it grows out of Proportion with other bacteria, clinic lives in the stomach and it can survive stomach acid in particular it shuts down your ability produce stomach acid. When that happens, you're not going to digest your food. Well, it can also be vector for other pathogens because. Stomach acid is a way that we sterilize our gut right? We sterilize food that's coming in, and now that when we don't produce enough now, it allows for more pathogens to come in and. Find home and start to. Cause more problems in our systems that would be one for example, that you look at parasites bacterial overgrowth all those things can be major issues. So infections definitely need to be addressed. What are some were? Some warning signs at somebody might have infection an infection. A Lotta digestive Dems so often have clients with bloating. Gas Constipation. Or. Diarrhea. Food intolerances were they just do not fill well after they eat some. Clients that can barely anything without.
"chronic inflammation" Discussed on Dr. Jockers Functional Nutrition
"And don't have pain when they walk I had one client that came to the clinic than work in and I'll never forget her I follow up visit and sheep teared up telling me how she doesn't hurt when she walks anymore she had an autoimmune condition that was really debilitating for her so it's just A lot it but it was all just think she was doing the the tips human I share with our clients. Yes she just started. And she was very dedicated in. She saw the results very quickly. Yeah that's amazing and so what are the root causes? You talked about the root cause of the re- 'cause. So what are some of the big root causes that you're seeing that are promoting inflammation? Well, Diane is always key. Yeah. We live in America and they call it the standard American or sad diet because it really is sad to say people eight foods that are available. And a lot of those shades or most of them causing inflammation. You know if you go fast foods or processed foods, high sugar foods, the could not Wales like the vegetable oils people think vegetable oil would be healthy because it says vegetable, but it's really not they're highly processed seed oils and the calls all this oxidative damage in our bodies. So the conventionally raised me in dairy. Gluten. Containing foods are all those are just very toxic bodies unlike my clients that suit can either hill or damaged. Everything they're putting in their mouth. You ask yourself is disturbing. Me Is giving me the nutrients I need to perform my best in kill my body because a really liked to look at it instead of as a diet as as a nutrition plan. So nutrient density plant based whole food diet really what I encourage my clients to have because they truly can hill their anti inflammatory foods. You're getting the grass fed meat and dairy the pasture chicken that. Non Starchy, vegetables is typically what I recommend. Some people do really well on some of the moderate carbohydrate vegetables, the vegetables can be very healing. But for most people there carbohydrate intake is too high creating blood sugar imbalances or really try to help people work on foods that can help steady their blood sugar ought to healthy fats like Avocados, olive oil and on grass-fed butters. Awesome. Then lots of herbs and also things like garlic in onions in tribe as I'm sulphur vegetables or great to add. So thing is really the first thing. I like the focus on with people. As, a great place to start because that's something out we can really control. And like you were talking about three big changes, number one getting rid of sugars in grains those promote inflammations like throwing gasoline on fire. Number. Two getting rid of the bad fats was processed vegetable oils like you talked about corn oil canola, soybean oil. You see those in processed foods. Also a lot of condiments you gotTa really look your condiments as well. The number three getting rid of the conventionally raised animal products we want. We want to go with the grass fed organic pasteurize animal products, significantly less toxic metabolites that are in those better fatty acid ratios were nutrient density. So it's always what we're looking for air. Now I know you've done advanced training in bio individual nutrition and so when he started to see certain patterns. Talk about some of the other therapeutic diets that use. Gift only like a low five Matt Diet I use that quite did of my clients have what's called small intestinal bacterial overgrowth or CBO, and even healthy foods can be high involved maps and include like fermented foods. So they can really see some relief of their symptoms with using low five APP diet. There's also diets like a low oxalate Diane. Diane. There's a variety of different diets. We really try to tailor diet to the individual. We don't have a one-size-fits-all Diet. So hitting what the individual persons dealing with. A lot of clients with autoimmune conditions, and we have an excellent autoimmune elimination program that I put people through the client I was mentioning earlier we that with her and it's elimination diet to really try to eliminate those foods that are causing that overactive immune response in the body because when a person has food sensitivity every time they eat that sued even healthy food sometimes. They can be sensitive to. So every time they eat the food, their immune system over response to the food in that creates a lot of inflammation. It can damage the gut lining like he was talking about earlier so i. have different nutrition plans and programmes really trying to. Take out foods that can be harming or creating an immune response in including foods that are healing in serving the person with where they are at the time. Yeah. There's a statement in natural health that says what maybe one man superfood may be another's poison rights. He could taking something like an egg or if you look at it from a nutritional bow chemistry perspective eggs are one of the most nutrient dense foods especially if you get organic pasteurized eggs so rich in healthy fats, fat soluble nutrients good clean highly bioavailable protein. However, there's A. Lot of individuals out there that have an immune reaction. So they're immune system gets fired up when they consume eggs, promotes massive amounts inflammation in their system. So we can't just look attritional quality food. We also have to have to consider how some reason yoon system is reacting to each particular food, and that's like what you were talking about, and that's really where by individual nutrition comes in. Because, if somebody's reacting to foods that are prebiotic foods, right we hear a lot about prebiotics being really healthy for the body. That's only for a certain percentage of the population. There's a percentage that. They have too much fermentation going on. In their small intestine like you're talking about that bacterial overgrowth and so they consume something like Broccoli or garlic or onions which permit nutritional chemistry perspective are great foods. But when they consume those, they get too much fermentation and there's a release of a lot of toxic compounds and that ends up creating bloating stimulates more inflammation throughout the body including issues that could affect the breen. Again, once the inflammatory cascade get set off, it can affect any single organ system to by for some people they get anxiety and brain fog and maybe fatigue that's those are related to inflammation in the brain for other people, they may end up getting eggs, Emma or rashes, or high of or something along those lines that's related inflammation in the skin for other people, they may end up starting to lose some hair and having trouble losing weight and. Getting constipated not could be inflammation of thyroid, right? So Depends on the individual and we're all unique but we've got look at those major.
"chronic inflammation" Discussed on Dr. Jockers Functional Nutrition
"Our website you'll have seen her work. She's one of our top writers crates, amazing content, and she's also been coaching people. She's a certified bio individual nutrition practitioner. And certified health coach and she's been working with people through my sight now for Gosh, about three or four years and taking care of at this point hundreds of of different clients with a wide variety of health conditions in seeing amazing results. So welcome to the PODCAST Melissa. Thank you excited to be here. Absolutely. Will I always love talking with you you're certainly a very, very bright mind. You're you're constantly looking at research and new findings that are coming out each and you're in the trenches working day by day with lots of people you're talking for the call busy you are with your coaching plans coaching schedule. And so I think it's important that people here from somebody that's really working one on one with I. Mean you probably have fifty clients actively clients right now and you're seeing so many different issues and so It's just so important we have this kind of conversation. So let's start by talking about what inflammation is what are some of the root causes they're creating inflammation. Yeah absolutely, and the reason I wanted to talk about inflammation is because like he said, I do see a variety of different conditions that people are experiencing and the thing that's at the root of most of them is inflammation. So everyone can benefit from what we're GonNa talk about today, check for reducing inflammation and really to heal. You got to implement these steps so. There's two types of inflammation not all inflammation as bad when were injured or our bodies encounter passage, and then we experienced acute inflammation and this is our natural protective mechanism of her body to help us hill. This last, just a short while and generally resolves itself a few days. What we're going to focus on today as more ECOMOG inflammation. So this is the inflammation. It's the low lying Chronic. long-term inflammation in based people experience some form of that. So there's a rod things that can cause it in it can lead to like we said a lot of conditions. He l. let's talk about some of the major symptoms that somebody might experience if they're if they're having chronic inflammation. Well there's a variety of symptoms definitely. So well, it depends on their condition that is being manifest by the chronic inflammation, but anything from car conditions, metabolic syndromes a lot of people have excess weight they can't get off due to insulin resistance. Liver issues they don't detox well because of inflammation in net, of course, it Canadian lead to things like cancer and Alzheimer's. For sure in why does the body create this kind of inflammatory process why you talked about acute inflammation? Why does it stay ongoing? Basically, what happens if limitation is very complex? So it involves the bunnies white blood cells that may produce different chemicals like antibodies inside kinds in these are released into the bladder, the affected tissues to try to help find the foreign invader. But what happens over time is? They are, but we can't. We're we're constantly dealing with an onslaught of different things. So I like to give my clients, this analogy, micro bodies, our bucket is so we constantly have things being put into the bucket like toxins and a poor diet and stress did not sleeping well in overtime our bucket gets full in in. That's usually when these chronic conditions manifest. So we've got to address all these things that are going into the bucket to help it from getting from spilling over into some type of serious condition. Yeah it's a great analogy understanding that you know your bucket may be filling up. Now you may not have any symptoms, but it may be filling up and you want to constantly be in a sense reducing the load that's on that and when I think about inflammation, you know we look at human history chronic infections have actually systemic infections have killed more people throughout. The history of mankind than anything else that would be like bacteria getting into your system getting into your brain and your spinal cord and causing meningitis die or bacterial pneumonia or something along those lines and so our body in order to survive humanity we've adapted. We've created this process called inflammation and inflammation protects us from dying quickly from an infection that spread throughout our body. And so that's a great thing. However, the problem is like you were saying when we have, for example, damage to our gut lining were constantly having bacteria, March proteins seeping into the bloodstream constantly telling the body while we're at risk for some sort of pathogen from invading the different tissues and creating this chronic systemic infection could kill me quickly. So we're constantly ramping up that inflammatory process and it's just an all day twenty, four seven. Thing that's happening plus for under stress your body associates stress with like being at risk for dying for example, you know so. Our bodies during the best candidate protect us from the thing that has killed more people throughout the history of mankind than anything else. But unfortunately, when we don't modulate that or balance that over time, it just damages tissues we can live a long time with chronic inflammation. We don't have well, and that's what we're seeing happening in our society today. What are some of the main tissues that we're seeing being damaged by inflammation? Well the brain the heart are to the mainland's any of our cells often see people with digestive issues due to chronic inflammation in loss of muscle tone like I said, wait gains a major issue. It even accelerate skin aging. So you can see it people scan I like to do Zun caused with my clients because I can tell a lot just by looking at them. You chronic inflammation just really common with people with joint pain and loss of -bility. So definitely something to address but. Our entire body can be affected by inflammation, and that's why it's so important to look at all the factors that are causing. It goes step by step with people you know to walk them through. What can you do because a lot of people come to me in they're hopeless about healing. Bendel. Doctors they've been on this healing journey for so long. That was my story. So I have set your heart for working with them in trying to give them that hope and motivation and empowerment. You really take steps to change their life in. He'll in the great thing about it is a lot of these things that causes inflammation are in our control we can really do a lot to. Mitigate the effects of inflammation by reducing our exposure so. If inflammation is the Ridge a disease. What's at the root of the root is what I like to say to people. So what what's causing that inflammation in? Let's go step by step in addressing those causes and over time you know people feel badly for so long they amish don't realize how badly they feel until they start feeling better in a row you in. So in a not be motivating in itself when they don't feel tired every day, they don't need a nap every day they wake up feeling refreshed in the ready to take on.
"chronic inflammation" Discussed on ECO CHIC
"I like adding it to sparkling water, and it's just a really delicious drink when you add it to sparkling water, so yeah time you could just go on and on, and then of course cooking with time has all those benefits and other thing about time in many of these other culinary spices, all of them really powerfully modulate inflammation and inflammation is something especially chronic inflammation that we're becoming increasingly aware of and how it plays an? Role many chronic illnesses, and so that question again becomes like you know what's causing this chronic inflammation. Why are we? Why do we have that? And of course there's no one reason by any means, but one one reason could be that we are missing out on foods that regularly helped to modulate inflammation in our bodies, and time is a really powerful way to do that as well so man he could. We could go on and on about time. Wow! Wow I would have never thought about time as so healing for the throat, and maybe that's just me. Being Unaware time is one that I just kind of add on top, because I haven't and I. Don't think too deeply about it. Which is sad now that I know of this because I'm definitely going to be doing that. Honey Apple cider vinegar infusion. I love adding things to sparkling water and making my sparkling water interesting. That's like by four. o'clock treat to myself is always like a flavored sparkling water way actually. Saying that the four o'clock slot to? Thought out that is so perfect exactly so that sounds awesome, and I'm also glad that you brought up honey, because when we think about natural remedies for the throw, my immediate thought is always honey when we talk about pollinators, herbs and relationships with the natural environment around us. I think that honey is a great gauge for that because it's very easy for people to now start thinking more consciously about buying local honey and. And supporting their beekeepers and this movement around save the bees, and by local honey, and honey is also a great way for people with allergies to help combat them a bit..
The Secrets of Wellness With Dr. Jeffrey Rediger
"Welcome to episode two hundred fifty five of live happy. Now I'm your host Paula Phelps. And I'm happy to have you back here again with us this week. This is a time when all of us are thinking a lot about healing and wellbeing. We have a lot of questions about wellness and today's guest is uniquely qualified to talk about that. Dr. Jeffrey Redder is on the Faculty of Harvard Medical School and his medical director of Mclean Hospital southeast adult psychiatric programs. He's a board certified psychiatrist with a Masters in Divinity from Princeton theological seminary and in two thousand fifteen he walked onto a tek stage and proposed a revolutionary idea to an audience of doctors. He challenged them to join him and create an a new kind of medicine built on hope and possibility rather than focusing on sickness and disease. His new book cured. The life-changing science of spontaneous healing provides a fascinating look into healing and how changing our beliefs about ourselves can change our outcomes. Let's hear what he has to say. Jeffrey thank you so much for joining us today on live happy. Now Glenn Beer well. We really wanted to talk to you because you have written a fascinating book and it looks at how people with illnesses. That were allegedly incurable. Were somehow spontaneously healed and I found this book so fascinating it really difficult to put it down and I wanted to know how you got started on this research. To begin with in. Two Thousand and two and oncology nurse at mass general in. Boston came to me and said that she had just been diagnosed with pancreatic cancer and she wanted to help her son about this. And so then she called me from a healing center saying that she was seeing some amazing recoveries and she alleged look into it and that time. I was a new medical director new faculty personnel harbored. I had just graduated from residency. Not that long ago the year before and I said No. I didn't think anything likely was going on there and refused but Nikki was persistent. She began having people. Call me from around the country and elsewhere saying that they had medical evidence for their recovery and did I want to hear their stories. I continued to say no for a while but letters were coming in and as I began to look at some of the stuff. That's being sent to me overtime. In spite of my resistance and my skepticism I began to become confused. Frankly because it looked like something in at least a few of these stories was going on and so long short of it is. I did begin researching the stories and that's been seventeen years now so things have gone a long way since then and how hard it sounds like. It really was difficult to reconcile what you were seeing with your medical education. That's very true. It was confusing to see stories coming in and having lab tests and by APPS results come in with cheers from cancer that I knew very well from my medical training were possible and so what I did was established three criteria and said that I wouldn't even look at the person story or listen to their story unless it really met these criteria so that I buy cherry was the person that had to have genuinely incurable illness. According to all the we currently understand number two they had to have medically indisputable evidence for accurate diagnosis and clear evidence for recovery and then number three there needed to not be any complicating factors such as an experimental medication or anything else that could potentially explain how the better so that helped me begin separating things out because certainly a lot of the story is a scheming and the data that was pouring in it was hard to know what really was going on because you know person can think that they got better but if they were also getting some kinds of chemotherapy and had certain kinds of diagnoses wasn't clear what was happening and so. I tried to just make the criteria really clear for the sake of efficiency and so I could figure out what's going on. And how many cases you say that you studied so this point of seventeen years. I've gone into over one hundred cases. It takes a long time to go into each case to separate out which of the cases that are genuine incurable and then to see if there is really good medical evidence to make sure there's not other complicating factors. Once you get through that level that removes a lot of cases and then from there to go deep into their lives and try to understand what are the factors that are associated that recovery takes a lot of work and so these cases are much more common than the research literature says. I've yet to give a talk where I'm not approached by someone afterwards at least one person who says either you need to talk to this patient where you need to talk to my aunt new talk to my cousin and most of the cases in company. I have not had time to go into this just because I have a job and responsibilities. So yeah how do you fit this research in with the fact that you do have a job as an RA small dog? How do you do all this well? This has been a very personal hashing for me at has grown over the years. I think I've always been driven by questions. And a stories raised a lot of questions for me and so it became something that I have spent a lot of early mornings on a lot of late nights and weekends over time and it's changed the way I think about a lot of things both as a human being and as a physician Woohoo or some of the commonalities that you found in the cases that you've been researching so feared I talk about the four pillars of healing and wellbeing and. I tried to tell stories that illustrate really well how these factors played a role in people's lives and I tried to choose stories from my research that illustrated really well how this works for people so the first pillar is nutrition. Nutrition is a big part of most people stories. Actually and it's not a one size fits all it's not like everyone became vegetarian or everyone followed the Atkins Diet or something like that. It's really a unique journey for each person. About what helped them feel better and feel their best and we all come from different parts of the world with our ancestors and that sort of thing and so I think different diets weren't better for different people. Some people went completely vegetarian. Other people chose a more ketosis diet. But what's true? Is that in nearly all of these diets? The commonalities were very real whether it's one type of nutritional plan or another almost. Everyone eliminated processed foods. They eliminated the vast majority of sugar foods from their diet. And also enriched flowers so they really began eating much more plant. Based Diet by enlarge. A number of people did eat meat but they tended to eat meat. That one person talk about eating animals had been happy when they were alive. Not with not with stress Hormones grass-fed so they get the healthier fats and knock on full of chemicals and so even though the diets looked different on the surface underneath there is a lot of similarity so that's efficient. The second pillar is that you need to heal your immune system so one of the really exciting things. That's just starting to happen. In medicine is that we're starting to realize that we've missed the real story about illness for decades as doctors. We are trained in body parts. If you're a cardiologist you studied the heart if you're a psychiatrist he studied the brain if you're a gastroenterologist he studied a GI system the gastrointestinal system excetera. But what we now are learning. And what these people with such remarkable recoveries have shown me with such clarity is that illness doesn't exist in these body. Parts as much as in the chronic inflammation that's created by our diets and lifestyles. And so if you want to heal your immune system then you need to lower the chronic inflammation in your body. That's really interesting as especially right now with people being concerned about the krona viruses and other things where they talk about. I need to jack up my immune system. I need to boost it up and no insane. I need to reduce inflammation. Yes but show. Chronic inflammation is immune system gone awry and is attacking your body for example. If you're causing little micro cuts in your endovascular system because of the kinds of food and sugar. You're ingesting constantly into your body. Then your immune system goes into repair mode constantly trying to repair all these little micro vascular cuts and injuries and not only. Are you expanding a lot of energy for your immune system to do that? You also are setting up. This scarring cycle in your endothelium. That is over time going to create hardening of the arteries so. It's not really a cholesterol problem than deeper level is it's an inflammation problem and the cholesterol is just a symptom of deeper chronic inflammation. And so we had this amazing immune system with all these brilliant cells and cell subtypes that want to do their job crisply and efficiently. But you have to give them the proper conditions so that they can do that and so I tell people to address the nutrition to avoid toxins to knock over. Medicate to flush lymphatic system regularly with lots of water to spend time with people. You love. Who Make you laugh? Because we know that laughter and positive authentic emotions are great for your immune system and to make sure you get plenty of rest. A lot of the things are things are moms told US growing up. She just kind of present it differently and didn't realize that she was giving. Us medical advice asks right. It's very true because your mom probably knew some common sense things that were more about seeing the forest for the trees in terms of what creates vital immune systems then what we were thinking about for a long time when we are just looking at the individual body parts. So it's not a diabetes problem. It's not a high blood pressure problem. It's not a cancer problem. It's not our problem or
The Health Benefits of Turmeric
"A bit of background about Turmeric Turmeric is a spice from the temperate. Plunked is is commonly used in Asian cuisine and has a yellow colored chemical which often gives the coloring to curry's for example cold cumin and again it's also used to flavour different Asian food as well. Curcumin is the main active ingredients and turmeric and has a powerful anti inflammatory effect is. It's a very strong antioxidant as well. You'll know from previous podcast episodes that anti-oxidants can help defend your cells from damage on this damages caused by potentially harmful molecules known as free radicals. It is worth mentioning before we continue this episode. That Cu Cuban human content of turmeric is not that high. It's around around three percent by bodyweight. Most studies conducted have looked at Turmeric extract which contain mostly itself so it's hard to get high doses of around one grandma day of curcumin just from the spice in your food. So we do want higher levels that you'd be to take it in a supplement of all so curcumin within turmeric is as anti inflammatory as I've mentioned and inflammation is important within the body to help your body fight foreign entities and help repair damaged in the short term however weather chronic inflammation can become a problem and scientists now actually believed that chronic load L. Inflammation can play a major role in a number of different conditions such as Heart Disease Cancer Metabolic Syndrome and many many more so the anti inflammatory properties of Kirkman Camby extremely beneficial. So what's actually going on here. Is that the curcumin is blocking a molecule called NF. K B that travels in the nuclei of your cells and it turns on the genes. The related to inflammation also believed play a major role in many chronic diseases. As of late as well there is evidence that suggests that turmeric can help alleviate. TV eight domes delayed onset muscle soreness a study called curcumin supplementation. Light play attenuates delayed onset muscle soreness looked at oral curcumin intake in seventeen men to determine the effects of curcumin or muscle damage inflammation and domes in humans. So the seventeen people were split into Placebo Group you and the group that took two point five grams of curcumin twice a day on there were evaluated by looking at single leg. Jump Performance and domes following unaccustomed uh-huh heavy eccentric exercise on the study found the top twenty four and forty eight hours post. Exercise curcumin caused motorists large reductions in pain injuring a single leg. Squats and Sir sheets with that. Pain reduction was also a small increase in single leg. Jump Performance and a small reduction in creating kind as activity. Not and Can Rise of skeletal muscle injury and Turmeric can reduce these levels. Therefore reducing indicators of muscle damage potentially aiding being recovery but of course more research needs to be done on this finally curcumin. The active ingredients in Tamarac has also been linked to improve brain function. So Kirkman has been found to increase brain levels of be D. and F. which is brain derived neurotrophic factor not say grow fall known functions in your brain in aiding the ability of your new Ron's to form new connections annisten Ted may age or memory recall and cognitive
The Ins and Outs of Elimination Diets
"I question let's keep it super basic as always elimination diets. What is the idea you behind doing an elimination diet? I'm going to say on the word. Elimination it's not to help you go to the bathroom. It's not that kind of elimination. So ideally the process of eliminating foods is I have susie. It's done with the supervision and and assistance of a medical professional and that it's safe and reliable so you determine food allergies and intolerances. That's the idea. I know that many the people on their own just temporarily scrapping what the down to the bare minimum and trying to eat clean and detox. Or what have you so. The basic basic premise is that by removing potentially offending foods and beverages and spices. Whatever you put in your mouth you're starting with a clean slate? And then the handful full of items that are safe you can begin adding them back or a type of food and for a few days see which items prompt the symptoms to reappear. Okay is who would benefit from this kind of diet is it. I would everyone. Are there people that don't need to worry about this diet. Surprised in in in looking at it that it's not just food allergies which I think we're going to get into but also there's so. There are different names of specific elimination diets. Hunch the autoimmune protocol and the Gut Psychology Syndrome Diet and the specific carbohydrate diet so I think it would be very targeted. has to whom it's going to apply to such as so the autoimmune protocol well that sounds more applicable to someone say with rheumatoid arthritis someone with that kind of condition that they have to manage on the other hand. There's the whole thirty that we've mentioned in a previous podcast. And you can kind kind of think of that challenges and Elimination Diet too. Because you're committing describing things for a period of time and it it does have a reintroduction face to kind of understand this little. Is this kind of what obviously to young children now. Is this kind of what we do with young children where you start introducing them to foods and you kind of you're like okay. I'm GonNa give him something with peanut butter and you're going to see how they do for a week or two hit the nail on the head. Zakariya weaning them off from breast milk or formula. It's what you do with solid food. It's like okay. We'll try rice. Cereal do that for a few days. Canal will try a little bit of green beans. Try that for the weekend and you just do like one in food at a time and make sure that they don't have an allergic response so it's very similar to solid food interaction with interesting and just a little tidbit it For Gloria out there. Today you tried mango for the first time. So and you get okay. Well how how long do you typically have to wait to gauge to see whether you're intolerant allergic is a pretty quickly or is it like you introduce a food and then you kinda gotta wait. Wait a couple of weeks before you move onto the next one. Well I thought it would be days or weeks and everybody's system and sensitivity is different so I asked a colleague and Jenny ask you a balanced alands fitness and nutrition in Georgia. said that client should feel better in ten days if they've eliminated the right foods so she runs blood. Work to create a customized plan. And so that way you know she can see exactly that they're getting the right items out and usually she says about fifty percent improvement in symptoms in the first two weeks which is kind of market? You know if you're gonNA commit to doing something he says and it Kinda go you want to be able to see that benefit right. Okay so I feel like for kids. It's easy to you know. Bricks slowly introducing them to new things that they've never had before but to eliminate something from our diet and then slowly reintroduce it. How is that on our digest? Is this some kind of a different game. Plan there so I would say that overall on the contrary most elimination diets. It's our intended to relieve gastrointestinal issues. Bloating gas so that's what the gap diet that Gut Psychology Syndrome Diet. Why it would do? But I've also heard from some people that say initially you know if they're doing the extreme elimination phase that they can get stomach aches from their extreme hunger so you could get a short term negative and then if you're eliminating certain foods you could get constipated just as as if you're replacing other foods with something you don't normally eat so much of raw vegetables runs. It's an adjustment period. And so what are some of the typical reasons people we kind of. You mentioned some used the elimination diet. I mean I've definitely heard allergies. That's one of the big ones is. You're trying to find out what you're tolerant too. But I've also heard. Is it like pain like maybe. That's another reason to to inflammation so again. Another one of my colleagues so Tammy Broderick of have healthy feet nutrition in southern California told me that elimination diets helped break. The cycle of chronic inflammation. So Gluten. Dairy sugar could could be the top three food offenders and gluten in particular is now being tied to like leaky Gut Syndrome but mother inflammatory suits could be soy and corn oil. Processed meats needs fried food. Alcohol Sodas and I didn't know that because I know in Allergies Brittany. The big eight are the common ones like egg and tree nuts peanuts peanuts wheat. Soy Milk fish shellfish those are the ones that typically have to be on a label knowledge statement. But they're all these other things can affect planet pain and inflammation as well. This time of day it would really help somebody who has maybe say like Crohn's disease or is like has it is or just finding out and finding a way to Yeah I. I won't even touch those because I'm not the digestive an expert so I'm going to Pass on that one but I know there's a lot of autoimmune Kinda in that realm exactly so it helps it helps you find what works best for your body and it's kind of like just to reiterate what I think we mentioned before but like this is meant to. You're not eliminating like one food food at a time and seeing if you feel better not eating it you're laminating several and then reintroducing them and seeing how you react once you reintroduce them catch food reintroduced is basically a challenge and so you're looking to see those adverse reactions in a few days which is where the commitment that consistency and logging in a diary you know comes in so you can't do this half half way you can't do it willy. Nilly or while you're trying to travel and have all these you you have to pay attention and so it's like. Oh well if I I feel heartburn or I feel this you know that it wasn't from stress or it wasn't from You know crazy sleep that you had or whatever so you're just really paying attention to each food and your good and your system and your anything your skin Dan.
NAD+, Nicotinamide Riboside, and Nicotinamide Mononucleotide with Rhonda Patrick
"I'm going to talk about a molecule that has become in recent eight years extremely relevant to the field of aging specifically. I'm referring to any D. plus which I will refer to. As N de for short and some of the related precursor molecules kills Nicotinamide riboside often referred to as an R. and nicotinamide mononucleosis tired often referred to as an these two precursor sir molecules are called an boosters which can both be found as consumer available supplements. Just in case. You've never heard of any. It's probably one of the most important molecules accuweather on the planet so important in fact that without it life would cease to exist to NATO boosters nicotinamide said nicotinamide mono nuclear tied at very high doses. This is an animal. Studies have both been shown to improve the way multiple tissues and cell types age including skeletal and heart muscle brain and stem cells. There have also I've been to preliminary clinical trials in humans showing nicotinamide riboside may raise energy levels in white blood cells. which is pretty darn cool however I still? I think there are many open questions that need to be answered regarding. Ad Boosters and I will touch on some of these concerns in this episode but the possibility that intracellular NASD may be increased from a supplement or several types of supplements is awfully interesting if not downright exciting for one. Simple reason energy levels decrease with age and a decrease in energy eighty levels across a variety of types of tissues is associated with many and naming many hallmarks of aging these hallmarks of aging that are associated with age related plated changes in the pool either directly or indirectly include things. Like loss of Proto. Stasis Might conroe Dysfunction Glucose Intolerance Insulin Insulin Resistance Cellular senescence altered epigenetics and more this is partly because the availability of promotes. DNA repair capacity while its decline is associated associated with the accumulation of DNA damaging reactive oxygen species another reason is because Nada's required for energy production so when energy levels decline as they do with age this results in less energy production in many tissues like the brain immune cells muscle etc.. That means those organs do not work as well as they once insted. During youth. When energy levels were maintained? Any ideas also required for the activation of a very important family of enzymes involved in longevity called Sir Tunes and the complete answer to why energy levels fall with age is still an open question. But there's a few things we do know. As we age chronic inflammation and immune activation two processes that consume NASD tend to go up and with them our need for DNA repair placing an immense demand on our energy pool. Meanwhile while our ability to produce and recycle tends to fall with age we're GONNA cover a lot of ground in this episode but I wanNA start with an overview of any D- Any any deal has a very important role in energy metabolism and can be synthesized in the body from a variety of dietary sources including the amino acid trip to fan which which is in tons of healthy foods like salmon spinach and nuts and the three forms of niacin which is vitamin B.. Three also found in foods like lean meats legumes veggies edges these three forms of vitamin B.. Three include nicotinamide also called Niacin nicotinic acid and nicotinamide riboside they are commonly referred to as Nice in equivalents but dietary sources of energy are not the major source of any D. The major source of energy is through a recycling mechanism that we will discuss later. The reason for that is because our organs require such large quantities of that it would be impossible to consume enough from our diet. So why why do we require such large quantities of any first and foremost energy plays a critical role in energy metabolism critical. Meaning without it. You can't make energy entity participates in back and forth processes of reduction and oxidation often referred to as Reebok's reactions these alternating conversions of NFC's oxidized form which Canady to its reduced form. An Age are crucial for the metabolism of glucose and fatty acids and the formation of ATP. Since both the oxidized is in reduced forms of amd are essential for these linked sets of reactions cells need to maintain massive concentrations of both and a D. and an age basically without these molecules. Not only would we cease to exist but life on our planet would cease to exist and it is also a cofactor for many different important enzymes in this context a cofactor means something that is required for an enzyme to work at has to bind to the enzyme and this activates the enzyme so it can performance function so. Let's talk about a few of these enzymes. Several these NATO required enzymes are inside the Mitochondria and this is another way and participates in the generation of energy aside from itself being a type of energetic currency it also acts as a cofactor for enzymes involved in the production of energy from glucose outside of the minor Qendra this is referred or to as glycolysis many types of cells us look like Hollis's as their primary source of energy. For example. Red Blood cells do not have any medical Andrea so one hundred percent of the energy. They require to perform their function of delivering oxygen and other goodies to other tissues in the body comes from glycolysis and plays a very important role in mitigating DNA. A damage you need repair damage to DNA. That is because any cofactor for one of the most important enzymes involved. In repairing DNA damage called part one the activation of part one requires an enormous amount of any D for example excessive DNA damage in subsequent one activation have been shown to decrease energy levels to twenty to thirty percent of its normal levels. The ability to repair DNA damage is important for longevity. LYMPHOBLASTIC cell lines established from blood samples of humans who were centenarians. One hundred years or older have significantly higher part one activity than cell lines established from younger individuals. That are seventy years old part. One activity has also been correlated with maximum lifespan. In mammals the higher the part one activity the longer lifespan. For example the activity of part one one was measured across multiple Mammalian species and the difference in powerpoint activity between the longest lived mammals tested which were humans and the shortest lived mammals tested. which were rats? It's was fivefold so not too much of a surprise but genomic stability which relies on energy in general and pop ones specifically maybe very important morton longevity is required to activate signaling proteins knowns or two which are highly conserved enzymes play roles in health span and longevity in multiple organisms uh-huh so to ends are linked to the regulation of variety of metabolic processes like the response to stress and the modulation of lifespan. The way they do this is through EPA genetic regulation so twins utilize ad to remove specific chemical structures called seal groups.
Cutting Just 300 Calories Per Day May Keep Your Heart Healthy
"Cutting just three hundred calories a day can impact your heart health serial a baked potato chicken salad soup and yes six oreo cookies one thing they all have in common they're all about three hundred calories new data from Duke health says simply cutting three hundred calories each day will not only help keep you trim it'll also be great for your heart a new study found shedding those three hundred calories each day improve levels of cholesterol blood pressure blood sugar another heart markers and after two years participants in the study showed a reduction in a biomarker that indicates chronic inflammation which has been linked to heart disease cancer and cognitive
How Gut Bacteria May Be Linked to Lupus
"Here's an article related to a link between the bacteria in your gut the intestinal microbiome and certain chronic diseases in this particular article has to do with lupus. Which is a systemic autoimmune disease that many of you have heard of and with any of these autoimmune diseases. It is your body's own immune system. The very thing that is supposed to keep us safe and healthy and pretty is attacking us. I tell my patients that it's a civil war inside your body with the immune system. It's like the police. Or attacking the good guys. And this particular study has found that within those people that have lupus or systemic lupus. S L E. Which causes chronic inflammation of the connective tissue involving things like your, cartilage and lining of blood vessels affecting by the way, one point five million Americans. They have found that a particular form of lupus that affects the kidneys. It's called lupus nephritis, which can be fatal. Can cause significant impairment of kidney function. They found that a certain microorganism or bacteria in the intestine was much higher. During these flares are exacerbated of lupus nephritis. And what they found is that a particular bacteria was found five times more likely. Rubino caucus nervous room in a caucus nervous in seventeen William will seventeen women that they studied. I'm sorry. Sixty one women diagnosed with lupus had five times the normal gut bacteria, then seventeen Williams similar ages and racial backgrounds that did not have lupus. So there were sixty one in the lupus category. Seventeen into control. They did not have excessive. This particular type of bacteria. And so we have known for quite a while that this imbalance of bacteria. This imbalance of the microbiome is associated with all sorts of of different diseases, everything from irritable bowel inflammatory, bowel disease, hypertension, certain heart issues. Lupus now lupus nephritis fatty liver and psoriasis. So these bacteria play a very delicate balance win we have the right amount of the good guys and the right amount of the bad guys. And there's growing evidence that a lot of these changes in the bacteria where you you. You lose the good bacteria in substituted for back. Abed bacteria is associated with what with what we eat processed foods stripped of fiber stripped of the nutrients tend to cause a shift to the more bad bacteria. So dietary fiber is key. Where do you get dietary fiber eat vegetables? There's also a fair amount of evidence that artificial sweeteners screw up these bacteria. So it's very interesting article. I posted it for those that have lupus, and maybe something for you to
"chronic inflammation" Discussed on Nature Podcast
"Lung cancer has been linked to chronic inflammation. The quite what the connection is between the two has been robbed unclear so scientists in the US turned to mice that have been genetically modified to develop tumors similar to a common form of lung cancer in humans the research has found differences in both the type and abundance of lung microbes found in the tomb ridden mice compared to those that remained cancer free. The microbes present in the cancerous mice boosted production of type of immune cell the produces and inflammatory protein, but germ free mice raised in a sterile environment. Didn't experience this suggesting that the microbes were playing a key role in Chula development. Check out that research in the journal cell. Discovering new medical drug is a loan and resource intensive process. It can take a decade or more for the drug to go from the drawing board to the hospital hospitals in a process involves a huge number of researchers. But for every the Manx it many more fall by the wayside in a process coast. Billions of dollars naturally research is a keen to streamline exceleron the discovery process in order to save money and time one possible way to do this is by using computer simulations to screen, a drug candidates wos is technologies existed for some time this week in nature as a paper describing how size is important in the world virtual screening as Brian Ralph new university of North Carolina. One of the co authors in the paper describes we were trying to basically see if we could enhance the. Process by several orders of magnitude by speeding up the initial screening process. The initial screen typically would take months, and is usually limited to say one hundred thousand compounds to to maybe a million compounds usually the initial screening in both physically testing thousands of compounds in this case relevant test in the activity of a relatively small number of compounds against a particular drug target in the lamp the team used a virtual library catalogue hundreds of millions of compounds. And so what we did here was we took advantage of a large resource of potential chemicals. These are chemicals that are theoretical in that they have have not yet been synthesized, but could be made by chemists using sort of common. Chemical reactions are typical chemical reactions. And this is using a resource called the zinc database, which was developed by my co authors, Brian show cat and a John Irwin at UCSF. And over the last few years they've been able to increase the size of the zinc database to nearly a billion compound. So a large number of compound so more compounds than one could ever physically screen using a lot of competing. Pella detained able to actually testing into actions of these compounds against a number of drug targets napr assist known as automated docking. You might think that simulating more automated docking would slow down the discovery process. But Brian suggests the for a number of reasons when it comes to virtual, libraries bak- is better. The main advantage of the large library is you get access to a large number of different KEMA type. So these different molecules with different shapes. And it's it's become clear over the past several years that if you have compounds that have unique shapes, then when they interact with the target, they're likely to have interesting biological activities that never would have been predicted before. And ultimately could be therapeutic in ways that were previously unanticipated by testing diverse array of chemical structures, including molecular shapes completely novel the team able to find interesting chemical reactions the haven't been seen before and they were able to quickly for example in just over a day. The researchers were able to Dutch -ly test over a hundred and fifty eight million compounds for ability to dock with the dopamine bull receptor a drug target for treatment of.
Gum infection could be linked to Alzheimer’s, study says
"Is that gum infection could be related to Alzheimer's. Wow. And I was talking to a dentist about this about what does this mean? And know one of the things he told me is just even gum inflammation. What to do is use warm water, salt water, gargle gargle, and that takes out, the inflammation. But the Alzheimer's so gum infection was found to be a potential risk factor for Alzheimer's. And this was a study deal. Let these back-back studies. This was a study published Wednesday in the journal of science advances. So this Jinja Vallis known as PG. Led to gum infection, chronic problems, and chronic inflammation of potential tooth loss. So think about that that same 'Bacterial found in fifty one out of fifty three brain autopsy is of Alzheimer's disease
"chronic inflammation" Discussed on Untangle
"And diabetes, and prostate cancer and high blood pressure and high cholesterol, and obesity, and Alzheimer's disease as being fundamentally different from each other that they're really. Not that they're different expressions of the same underlying biological mechanisms things like chronic inflammation, oxidative stress changes angiogenesis in the micro biomass in gene, expression, telomeres and in. Hey, Potosi and other things like that. And in turn each one of these mechanisms is directly influenced by what we eat how we respond to stress how much exercise we get and how much love and support we have. And so although there's a lot of talk about personalized medicine personalize this. I mean, if you're talking about a targeted immunotherapy for a particular type of pancreatic cancer melanoma. That's awesome. But for the vast majority of chronic diseases in our forty years of research, it wasn't like there was one set of diet much sub recommendations for reversing heart disease and a different one for reversing prostate cancer, diabetes, or whatever it was the same for all of them that again, it's because they all share the same underlying mechanisms it also helps explain why so many people have so many of these diseases at the same time. Many times people have cholesterol high blood pressure. Be overweight, they'll have heart disease because it's not like they have four different diseases. There's it's really the same disease manifesting different ways. So this is fascinating most of the disease that we have stems essentially from eating poorly, not moving and not having loving connection and being too stressed. That's right. And also we found that you know after doing this work for forty years. I think this is finally the right idea the right time because on the one hand, for example, eight randomized trials has shown that in men and women who have coronary heart disease, and they're stable stench classes, really don't work, they don't prolong life than or prevent heart attacks. They don't reduce angina. You know, we spend tens of billions of dollars these each year for this operation, that's really not affective dangerous expensive and and ineffective. If you look at tattoo diabetes. The studies were showing the getting your blood sugar down with drugs does have help prevent the horrible complications.
"chronic inflammation" Discussed on Newsradio 970 WFLA
"I open it's a roadmap to your health, you, learn about. Your what is it The body mass index and body fat, percentage in. Your hydration levels and all of that to three hundred dollar value if you use code Ryan r. y. n. you can get that for only twenty seven dollars and. And really the. Key number data or shop before we get to our next guest Pasha in a. Moment to key, number that I was most, fascinated with and concerned about was my visceral. Fat number yeah very very specific and I do I. Wish everyone in our community understood what is exactly your visceral fat radio what's intriguing about that number is every. Surgeon I mean this every surgeon every medical. Doctor that comes into my facility. They all point to, graph number four right which is your specific visceral fat rating but that dangerous really aggressive fat that surrounds the heart the lungs the, liver the kidney. The pancreas it, just produces a high level of. Toxicology it creates a, high level of Chronic inflammation and it's so unique this is why I want patients in our facility, but as we take them through this protocol almost, physiologically speaking it's almost, hand but your level of toxicity your level of chronic inflammation will dissipate at a super dramatic pace but it's all the things we talk about the. Way you sleep the way you rest the way you breathe the way you move but really tapping into that energy tapping into that fountain of youth I don't want weight loss I want very specific fat metabolism but it's turning that body back on I want your system to flourish I want your. Health, to, take off but I want. To rebuild kind of that metabolism which is so critical now is the number. I wanted to get under control I did. An alum obsessed with the body fat percentage that's that's my number that, I look at every day because you, you? Just it becomes a habit we've talked, about this on the show before you go on the, scale every, day you, check your, numbers and, and that's what you you know you do. And that's how you stay account Able to yourself let's go to the phone, lines now Pasha joins, the shell Pasha how are you I'm doing great. How are you Ryan. Good thank you so much for taking the time to talk to us today so let me go I always like to go back to the beginning because I kind. Of want. To. Get a what year state of mind was like and what your physical issues war desperate desperate okay so explain what exactly was going on. That made you decide to to do. The.
"chronic inflammation" Discussed on KWAI 1080 AM
"To to defend and and ward those off as your immune system weakens with age you're thymus gland begins to shrink when you foreign it's about the size of naval oranges largest organ in your body as you get into your twenties starts to reduce by thirty it's about the size of a walnut by forty it's about the size of a p into your fifties looks like a little droplet of fat hanging by a string and and this is the reason why preview bessant and and people more mature into their late forties and fifties become more likely for chronic disease and even even terminal diseases because our immune system weakens so when one of the symptoms of this on on this dialogue that i somehow launched into sherry beg your pardon is is inflammation that's a good sign that's that your body's first line defense but chronic inflammation mation leads to a number of diseases in it's well documented as a matter of fact they chronic inflammation and and auto immune disorders like that lead to things as as perot psoriasis the you can see it on your skin it's it's the thick reddened skin scales flare dermot often in the skin and in joint structures which which causes and contributes to scar tissue chronic fatigue syndrome if any of you are suffering from this often misdiagnosed or non diagnosis syndrome it it is real and and you're you may want to listen intently here your inflammatory bowel disease which which often is diagnosed as all sort of colitis or crohn's disease that's that's it may be just as as as minor for you as frequent diarrhea and abdominal pain addison's disease which is the adrenal glands hashimoto's disease thyroiditis many people in america began to suffer from that fibromyalgia again another often undiagnosed or misdiagnosed that's the muscle and soft tissue surrounding the joints causing chronic pain and tenderness in specific sites rheumatoid arthritis nearly everybody knows what this is you probably have a relatively may be experiencing this yourself the joint inflammation and pain and defamation that goes along with it lupus affecting the.
"chronic inflammation" Discussed on KWAI 1080 AM
"Defend and and ward those off as your immune system weakens with age you're thymus gland begins to shrink when you're born it's about the size of naval oranges largest organ in your body as as you get into your twenties starts to reduce by thirty it's about the size of a walnut by forty it's about the size of a p into your fifties looks like a little droplet of fat hanging by a string and and this is the reason why preview bessant and and people more mature in into their late forties and fifties become more likely for chronic disease and even even terminal diseases because our immune system weakens so when one of the symptoms of this on this dialogue that i somehow launched into sherry beg your pardon is is inflammation that's a good sign that's that your body's first line defense but chronic inflammation leads to a number of diseases in it's well documented as a matter of fact they chronic inflammation an auto immune disorders like that lead to things as farrah psoriasis the you you can see it on your skin it's it's the thick reddened skin scale splitter dermot often in the skin and in joint structures which which causes and contributes to scar tissue chronic fatigue syndrome if any of you are suffering from this often misdiagnosed or non diagnosed syndrome it is real and.
"chronic inflammation" Discussed on WDRC
"Specific methods legal undertake lee believe it or not they wanted to help out eighteen inches of mine tested and i said no let me give it a natural try and i probably uruguay from way back when yeah i'm going to tell die if fish oriel el glued amene particularly were the the one i really concentrated on eventually things got settled down believe it or not 25 years later well i certainly believe it because we see again and again and the other diet that we favour for this is something called the scd the specific carbohydrate died which i can't claim credit for because i learned it from elaine god shell the originator of the diet who herself borrowed the diet paradigm from a german physician who learned about it in the early 20th century so anyway i when it comes to mushrooms if you have a structure which means they're scarring there's a bottleneck in your intestines due to chronic inflammation which causes corny that's pretty common in patients with crohn's disease that there's some narrowing due to chronic inflammation and scarring mushrooms and i i've learned this from patients mushrooms are no no if you have a stricture or if you have episodes of obstruction which can happen if things get cut a bottled up and stuck there because mushrooms act like sponges they absorb a lot of water and they swell and they can clog the narrowed passage ways in the intestinal tract so we learned through bitter experience that while mushrooms may be allowed from the standpoint they're not causing an allergy they're not you know full of sugar their natural the nice high fiber of beneficial nutrients oh just from physical standpoint they may have sponge like characteristics probably not for you because you been remission for a long time you don't have a lot of scarring and you should do okay so give a shot pension that creep out at you know congratulations to you like and and your idea it's important that i think could people i q share your experiences so that those suffering from crohn's disease know that there are natural options natural alternatives that can really turned the condition around a number one is diet but we also talk about other methods low dose no trek so now canada dialers cb ds help for sufferers there many nutrients that are helpful like occur cumin and fish oil as you.
"chronic inflammation" Discussed on WTMA
"First thing you should be doing is kind of warring of being worrying about digesting better but the reason why i'm is because a lot of times that these things go handinhand so a couple of the solutions kinda give ya on the kind of help with this the first thing you can do which is a very very easy step it takes really know kind of timer energy at all the really do this but again if you feel like you're inflamed and you need to digest better i would recommend you even doing something like an apple cider vinegar which is which is very easy do you throw you know maybe a tablespoon or two tablespoons in water you know before about thirty to forty five minutes before you eat a meal and this guy she help with digestion so the better you digest the less responds or chance you are you're buys in again become inflamed or also to you know if you don't digest all the food particles you eat these particles ask you want to you're hitting your gut lining became kind of worked away through the gut lining into your blood and now she can cause this inflammatory response lead to chronic inflammation so again if inflammation is a problem for you the first thing you to focus on is digesting better and it will always help i know it seems controversy indicated we said okay so that's how you can of hewliss from a church we said also to you know you have to have that nerve system them you know kind of evaluated because you know if you're doing all these right things nutritionally and you know if we qatar you just take a person and cut all year stomachrelated digestive system i you know your gut would now work at all it's very simple equation your brain has to have control your brain controls your got your brain controls your arm your brain controls everything so that communication between your brain your body disconnected those organs don't work now we said that earlier leader if you haven't had that connection checking to make sure you call us up here you at five five six.
"chronic inflammation" Discussed on WSRQ Talk Radio
"Because i don't have chronic inflammation but i have many girlfriends especially and friends that have chronic inflammation like my one fan she gets up in the morning and she's got to take a hot bat before she could started on the day just because of the aches what is causing this inflammatory condition that now seems to be an indicator in major degenerative diseases on on it is really the indicator and i think pretty much every disease that we have inflammation and something that we have done to art felt we leave incredibly struck whole lifestyle we don't eat correctly we don't we don't exercise we don't breathe clean air we are in on and contact with chemical or an hot and contract with light we don't ground the earth anymore i think it's a combination of all of that i know some that found a little out there aren't weird but a inflammation and you can't deny that inflammation causes heart disease or what causes diabetes or what causes it'll be headache or will call those eight and pain that your friend has every single morning it not normal wake up with eight and paint like that and it's normal to wake up and take a um alive and it's another day let's go to work or let go play tanit so let go do whatever it makes you happy but that really to me to be bogged down inflammation and let's not forget that imf one man who live and reside in at belly fat that most people have that belly fat is just one big alop of inflammatory what we call quite a kind.