31 Burst results for "Carty"

"carty" Discussed on The Adam Buxton Podcast

The Adam Buxton Podcast

10:07 min | 3 months ago

"carty" Discussed on The Adam Buxton Podcast

"He's quite an extraordinary person so he is to go back to alexis routine right. He's running along listening to an audio book about the third reich when he gets back cold shower of course it is. Isn't he tired of never going for the cold shower option candies. Have i ever any in jamaica. Have i had a cold shower. Because the option. It's that called because of their size and the war gets warm but apart from that never hear of a working. Boiler convicts boiler. I'm not going to do. I'm going to do it by choice. Or even if i didn't have a choice once or twice i've had a cold shower and thought that was invigorating. I get really yeah. I've had a couple of good cold shower experiences. I think it would make give me a cold. I agree back to the lex. Friedman verse time for eating lexi's on the keto diet low carb high fat the rest of the time fasting drinking water taking your sodium tablets having his carrots when it's party time that's his party vegetable then it's time for shallow work session and he is checking his emails. He might check his emails three times a day now. That is something that you do to keep a lid on though. Don't you find 'cause. I imagine when you have a book coming out and when you're doing promo and stuff like that it's just you can spend the entire day looking at emails right so i have like you've seen it now. Let quite strict out of office. The is i if you don't need to talk to me here. Is everyone else that you could talk to instead. And i may maybe cost iona. So that just absolves me of responsibility of emails. I think but i you know i do. And sometimes they most an ice and so enjoyed. But generally i ignore of stuff because it's just so loud you know what i mean. Everything is so loud and so demanding. And i'm just a mouse. You can't get at me. I'm like a teenager. You probably what this out by now. What were you like when you were a teenager. We trouble was yeah. I was what flavor of trouble. Choose switch to give very challenging. I was always described. It was very challenging and various certified as arsenal of questions. I didn't understand the answers to. Because now i'm older adults chat shit a lot of the time and they try and spin the logic and sideways question it because that doesn't make sense. Mum like dad doesn't sound true. And then i get in trouble but i'm glad i was like that. Yeah it's good to us questioning. Mind the questioning mind yeah. There's nothing wrong with that. We're coming to the end of lex. Friedman's day this final shallow work session. Where he's checking his emails and editing podcasts. That's the other thing. He's got one of these podcasts. They sometimes talk to people about three hours on them. Hourigan isn't it. Yeah but on the other hand he's quite good like he keeps it interesting. He's intelligent anyway. When lex is doing his shallow work session. That might be the time. Where if things get crazy he might have a little dinky. It's been known to happen right. And then it's time in the hour or so before he goes to for reading one hour of reading scientific papers and then what lex cools fund reading and at the time of his video. He was working through. The major novels of dostoyevsky he just finished the idiot and now he was starting crime and punishment reading it in both english and in the original russian. I'm just saying i'm just thinking. I'm thinking so many things i come night. He probably is having fun and icon. You know something called a boring guy. But then i'm not yet but he's really enjoying himself. Who am icicle him boring because he would find. Maybe what i do really boring. But he shouldn't. Because i do fun things but like he's obviously really happy with what he's going on even though i can't access that for myself i'm just thinking things. Oh may what is your idea of fun like. What is the most fun thing that you can do on a regular basis. The most fun i can do is exactly just reading. But it's just more fun than that crime and punishment of you raise the organization watching staff. Have i read punishment. Absolutely not stay long. Have you know my brothers read it. Actually my brother is a computer guy as well. Perhaps his and lex friedman's more closely aligned. There's certain people who are like that. They they just read big classic books. Classic literature. I didn't have the attention span for any of that to know exactly. What's the last enjoyable book that you read. Then let me say enjoyable. What we saying a book that you didn't have to struggle through a book where you weren't constantly thinking if this doesn't get good in the next chapter i'm gonna give up. Oh god where you're constantly just thinking. Oh i'm looking forward to this. And oh i better stop reading because i need some sleep but i could easily carry on. Okay i read. It's not like enjoyable. But i read an american marriage by terry jones. And that's the book. That i read that i was i got you have to go to sleep and i read it into savings because i was i is so gripping and i love i love these people. I wanna there okay. 'cause i bet you now that you're a successful published author. I bet people send their books to you a lot right. yes they do. And that's tough especially if you know the person and they send you or maybe you've just met them once. Maybe they're just a a very Passing acquaintance but they send you the book and you feel like oh shit. I better read this but then it's like i've got a big pile of that i haven't read. That's been there for years and years and years and now another one. Yeah all the time but actually if someone that you know then. You're just happy to do it. I'm happy to do it. Yeah very honored to be asked. Obviously you're having written as well. What goes into it is so extreme and you want to respect someone that you care about has done that or anyone really because it's fucking undertaking. It's exhausting it really is. It's emotionally exhausting uniquely. So i imagine that it must have been very emotionally shredding to write parts of queenie. Because i imagine that you would have been drawing on some of your own experience of of some of those things. Is that right not necessarily the bits that i found the hardest to write with with her mom and i would cry when i was writing those bits just because i really loved those characters by that point but will i have known so many people's relationships with their moms where they haven't felt loved or cared for haven't been supported or even looks after very base level by their moms and so having to channel something that i've had so frequently or just have witnessed or understood was really tough because i just loved them. Both the knows. Why was it not better for year. But i enjoyed writing most of because. She's just reckless. It was just like what mad fin. You're going to have this girl do now and i could just do it in the second half the book then she starts gradually getting her act together all thinking about how she can change her life in a positive way and part of that is going to a therapist. Those scenes felt very authentic. We recalling i mean. I've just started having therapy this year. Chelation yes thank you. Was that something. That was a familiar routine to you already or so. I thought therapy real long time ago. And i've only just gone back into as of the dos aac fema On zoom and so. It wasn't recalling anything. I'd stood for myself in my in therapy sessions. It was just more. Like i now therapists talk very well and so it was actually quite nice to be writing in those ways. Yeah we've reached the end of lex friedman's day. The last thing he does before falling asleep is returning to an earlier mantra from the beginning of the day and he considers with gratitude that he's still alive and he's made it through another day so he's got a very positive routine going Speaking of therapy. I actually told my therapist about lex. Redman's routine is described it to a and She rolled her eyes. Because also i just wonder how sustainable this is via him. That's the thing isn't it. Well control thing. Are you trying to fulfil what happens when you do fulfill it. Yeah i mean he's a. He's a single guy in his thirties. So i suppose it's more feasible to have that level of control when you're in that position because what happens if he does meet someone. Yeah exactly then. Having that rigid a routine is really going to cause a problem. It's not going to be impacting. it's not going to be fun to go out with someone. He's i've just got to go for seven mile run. I'll see you in an actually when i get back. I'm going to have to do twenty minutes of exercise. And then i caught a child but i can fit you in for five minutes after that you for my second four hour work session but you know. I know that part of me is slightly poking fun because i envy that level of control. I mean that is this part of me that thinks. Wow that would be.

lex friedman lex jamaica alexis lexi Hourigan dostoyevsky terry jones Redman
"carty" Discussed on The Adam Buxton Podcast

The Adam Buxton Podcast

08:33 min | 3 months ago

"carty" Discussed on The Adam Buxton Podcast

"Back excellent relieved. Yeah feel great. It's the worst feeling is it's harmful like i actually get quite shaky. What would if you need the horrible. Have you ever been in a situation where you can't go and it's becoming an emergency. No i think. I tricked myself into thinking. It's going to be even worse than it is. Do you know what. I mean. So that when i was in meetings we like oh my god and i was convinced i was gonna wet myself but i never have as an adult. I've got so many traumatic. We we memories. Why the because of times. When i just needed to go and i was embarrassed because i'd probably just gone about ten minutes before and i didn't want people to think i was a little. Pp freak and. i didn't want to cause a fuss. And i didn't want people to be looking at me. You know what i mean. Yes so interesting. So the king is interesting. Yeah just because of the way just because of we. Yeah but i think the the idea that people knew something embarrassing about people knowing that you need a we d think that i guess i must do otherwise. Why would it be a problem. But i do think people actually would leave that situation. Gosh really need to wait. And then i had another one though when i never mind the buzzcocks years ago it was when marc lamont was the host and i was on phil jupiter his team and they used to give you. Maybe they still do they ply with booze right To make you more fun. 'cause booze equals fun of course so i drank three or four bottles beer before we even started taping and said the prize. I needed to do away. Yeah and they tape for about three hours. Sometimes those shows a long time. And so i lost it as long as i could is about an hour in and then eventually i couldn't take it anymore and i just raised my hand thinking i'll make a joke out of this because you know there's an audience there and everything. I raised my hand. And i said. Excuse me sir tacoma can. I be excused please. Everything went silent and the audience. Like i was hoping that the audience would laugh but they didn't laugh. God's a martin was like what. And i need a we thought. What are you. Sure thought of that before we started taping. We're doing this as live. Whatever that means and so okay and we just had to carry on high seriously. Yeah we had to carry on but for only about fifteen minutes or so. And then eventually i hadn't said a single thing and i was about to. He could say. I was about to raise my hand again because like this is a nightmare. What's going on in. I don't think he liked me very much. And then he said go on then but the quick was like being told off was awful. And as i got up i kicked over a couple of empty beer bottles and they clattered very loudly on the concrete floor. The studio and everything was quiet. And the audience were quiet and crept out. And i went to the blue and when i was in the lou just thought fuck this. I'm not going to go back in digitally did because i thought it through. I thought it would be. I'd love to run away right now and never do anything like this again but my agent would be embarrassed isn't it. It's a contractual thing with most things. Yeah have you ever had anything like that. Luckily ling no. Because i'm the sort of person. Not public toilets. So i'll get on a plane been toward a maybe three times and a half. And he's the toilet were. Yeah that's eight and a half. That's eleven hours isn't it so now. Yeah because i just. I'm just not happen. And just tell them my bladder brain but we're not didn't it so then it's fine. I'm actually that's like one of my cisco because probably quite unhealthy but yes. I can't finish with any stories like that. Because i just have bladder of steel. That is very impressive. And you stopping yourself from drinking and eating before the flight in order to reduce the likelihood of you needing to go. I just didn't have t on it really drink alcohol. So that's fine talk tips. How about than just moments like the one i had in the lou where i just thought fuck this. I'm going to just run away not necessarily toilet based but just moments where you feel out of your depth professionally. We were no because what you know. What actually. When i worked in publishing i was often if not always the only black person on any black woman in the room and so there was always so much going through my head all the time i was always i call. You deserve to be here. And so i think having done that for so many years when i go into being a writer i guess and just having right now you kinda deserve to be. You've gone for a lo- so there was a lot of those situations to me was very hostile because when you look around the room and no one that was like hugh. It's a very alarming thing. There's a lot of stuff happening in your subconscious. I guess how did you come to be in that position because that is similar to queenie in the book. Isn't it that she is in this environment where she is often the only person that looks like her and she's working with a lot of white people she's going out with a lot of white guys and that's something that i notice people picking up on. I watched a few people doing logs on youtube about the book. Then if you've delved into that world ni- i have not. I haven't wow holy moses. I mean it gave me the chills just thinking. Oh my god. Maybe someone's done something similar with my book. But i certainly wouldn't seek it out. I notice though that people have a tendency especially with fiction to be quite literal minded again you know to review the book based on how they felt about the central character so people will almost reviewing queenie as a person yeah and judging her quite harshly on her choices. Yeah i've seen this a lot. And i've been that people have come up to me on the tube and been. Why did she only white guys. and i'm like she's not texture and askar. She's a character that of made and there's obviously reasons but people do respond to her. She's a real person and so yeah there is. There is a lot of enjoy it. Because i said like a conflict is or chaos. Not new things to me. So i'm like okay if that's happening over there i'm just over here is there is a reason internally why. She only dates white guys in that book. It's all sort of laid out for you. This is part of a person who's in turmoil and all sorts of ways and ends up. She's on a mission to figure out a load of things about herself and she is enacting all kinds of neurosis and that's in forming lot of her behavior and her hookups with unsuitable. Men and things like that so it's all in there but people. I got the impression because it's a book about a young black woman that comes with a load of responsibility in their minds. You know it's like well there's not too many of these books out there so you better portray a young black woman in a way that we can get behind. Did you feel that responsibility. I didn't because it's not my job. My job is to write the story that i want to write. You know the problem is there isn't enough of that fiction around and so when you are one of the first to do it. I guess i was one of the first to do it in the time that i did it. I know i'm not the first black woman to write about black woman but when you do people are asking for these characters to almost be perfect to what they would do and say you right then you right. One is great. And that's kind of why. I don't ever feel i don't ever feel offended. By critique of the book because i did one piece of work done icon. Serve everyone you know. Yes and also it was not the opinion of everybody. I mean the books done amazingly well. Congratulations on it. And i read a comment from someone. Who said i think what i liked. Most is that the character of queenie was flawed. And not just primin perfect. Someone who never made bad decisions made it realistic. I think it also.

lou queenie tacoma youtube marc lamont ling writer
Tuning the CAR T

Sounds of Science

04:54 min | 9 months ago

Tuning the CAR T

"I've always liked the word camera. It's one of those difficult to pronounce words that has many exciting definitions. Is it an ancient Greek monster cobbled together from several fearsome creatures? Is it an illusory pipe dream a wispy Mirage on the horizon or something from the island of Dr? Moreau each instance features heavily in some of my favorite fantasy books as a kid. Today is part of the subject of our podcast kyw Merrick Antigen Receptor T. cells better known as carty cells. You're in the real world. These Americ- antigens are much better than fantasy. They life changing therapies here to speak about these wondrous cells is Sunday. Halt! Group leader Biology for Charles Rivers Light. Incite welcome Sanni. Hi Mary thank you for having me. Thank you for being here. So I some background. Could you explain what these engineered cells are before? We get into how they're used? How long have they been around? Absolutely so t cells are cells near immune system that played important role in eliminating foreign. Foreign invaders they do so through target specific binding using receptors on their surface who owns a t.? Cell binds at it triggers the cascade which can lead to killing of the infected cells, commerical Antigen, receptor, or car you mentioned can be designed in a lap to bind only one specific target. If you add these engineers car onto a T. Cell, you generate new T. cell, which has the ability to bind and kill specific cells which express that target that you designed your car for okay defers, clinical trials into RT sells for a really reported, trying to buy two thousand and five and currently being. Over five hundred trials ongoing said this is a massive increase and really shows potential that these Arabs have. Currently there to fully APPREC- cartoon south at on the market, which I was approved in two thousand, seventeen so Howard, these sells used in cancer treatments so cancer, except it's very different expression profiles than normal cells. If you can find a target on a cancer cell, which is not present on healthy cells, you can design a car against his target by then treating these cancer patients with the cartel cells designed against cancer specific target, the Kartini cells will kill the cancer cells, but touch any healthy cells. This would be a major improvement over current chemotherapies or also healthy cells are killed. It also makes cancer treatment a lot more personalized for each patient. Unfortunately, it's not quite as simple as making it saint, and these therapies all that they have major potential have some serious challenges so basically what you're saying is you can design. Like a normal human immune cell, but give it a a sort of a key that will fit only into the specific cancers lock exactly that's very wave describing it, so this has been going on for a while as you said, but you mentioned that there's sort of a a new up start, which is t cell receptor therapy? Can you tell me about that? And why? It might be a better alternative? He absolutely so I'm not entirely sure of could call it a better alternative, but they're definitely turn it, and they've got some pros and cons same, said the car t-cells, so t cell receptor therapies are t, crt cells are. Are, in many ways similar to cells where you do engineer receptor onto a T. cell in this case, you just engineer a tea CR onto it instead of a car, the advantages, but also some challenges of t cells is that they bind through h receptor on the one hand. This means that you can actually select from much larger set of targets, which increases the chances that you can find that one target that's only expressed on cancer cells, but not on healthy cells, and on the other hand it also limits ED patient population because people have very different lots of different types at an it makes a safety testing in animals. Very close to impossible. You mentioned earlier. That safety can be a real concern. We can talk about I about some of the reasons. Safety needs to be so so thorough I understand that these can have some really serious side effects. So can you talk about those little bit? He yes, absolutely so as she mentioned your metaphor if she give these cells, the receptor, which could be key. Key and then it only fits in the lack of a cancer cell. You need to make sure that the key doesn't work on any other locks, and so if the target expressed on the cancer cell that you've designed to St CRT, sell or your car, T. Cell Four. You need to make sure that that target is not expressed on any other healthy tissue if Any of your organs express that same target, the Tesol will bind kill also your healthy cells near healthy organs, and that's something yet. You very clearly want to avoid.

Engineer Mary Moreau Carty Charles Rivers Light RT Group Leader Howard
Tuning the CAR T

Sounds of Science

04:00 min | 9 months ago

Tuning the CAR T

"I've always liked the word camera. It's one of those difficult to pronounce words that has many exciting definitions. Is it an ancient Greek monster cobbled together from several fearsome creatures? Is it an illusory pipe dream a wispy Mirage on the horizon or something from the island of Dr? Moreau each instance features heavily in some of my favorite fantasy books as a kid. Today is part of the subject of our podcast kyw Merrick Antigen Receptor T. cells better known as carty cells. You're in the real world. These Americ- antigens are much better than fantasy. They life changing therapies here to speak about these wondrous cells is Sunday. Halt! Group leader Biology for Charles Rivers Light. Incite welcome Sanni. Hi Mary thank you for having me. Thank you for being here. So I some background. Could you explain what these engineered cells are before? We get into how they're used? How long have they been around? Absolutely so t cells are cells near immune system that played important role in eliminating foreign. Foreign invaders they do so through target specific binding using receptors on their surface who owns a t.? Cell binds at it triggers the cascade which can lead to killing of the infected cells, commerical Antigen, receptor, or car you mentioned can be designed in a lap to bind only one specific target. If you add these engineers car onto a T. Cell, you generate new T. cell, which has the ability to bind and kill specific cells which express that target that you designed your car for okay defers, clinical trials into RT sells for a really reported, trying to buy two thousand and five and currently being. Over five hundred trials ongoing said this is a massive increase and really shows potential that these Arabs have. Currently there to fully APPREC- cartoon south at on the market, which I was approved in two thousand, seventeen so Howard, these sells used in cancer treatments so cancer, except it's very different expression profiles than normal cells. If you can find a target on a cancer cell, which is not present on healthy cells, you can design a car against his target by then treating these cancer patients with the cartel cells designed against cancer specific target, the Kartini cells will kill the cancer cells, but touch any healthy cells. This would be a major improvement over current chemotherapies or also healthy cells are killed. It also makes cancer treatment a lot more personalized for each patient. Unfortunately, it's not quite as simple as making it saint, and these therapies all that they have major potential have some serious challenges so basically what you're saying is you can design. Like a normal human immune cell, but give it a a sort of a key that will fit only into the specific cancers lock exactly that's very wave describing it, so this has been going on for a while as you said, but you mentioned that there's sort of a a new up start, which is t cell receptor therapy? Can you tell me about that? And why? It might be a better alternative? He absolutely so I'm not entirely sure of could call it a better alternative, but they're definitely turn it, and they've got some pros and cons same, said the car t-cells, so t cell receptor therapies are t, crt cells are. Are, in many ways similar to cells where you do engineer receptor onto a T. cell in this case, you just engineer a tea CR onto it instead of a car, the advantages, but also some challenges of t cells is that they bind through h receptor on the one hand. This means that you can actually select from much larger set of targets, which increases the chances that you can find that one target that's only expressed on cancer cells, but not on healthy cells, and on the other hand it also limits ED patient population because people have very different lots of different types at an it makes a safety testing in animals. Very close to impossible.

Engineer Mary Carty Moreau Charles Rivers Light RT Group Leader Howard
Did Covid-19 Coronavirus Escape From A Lab In Wuhan?

Mark Reardon

05:55 min | 11 months ago

Did Covid-19 Coronavirus Escape From A Lab In Wuhan?

"The house will vote today on another coronavirus relief bill right now because I I do hear from folks pretty constantly about the we have lab and investigating we have left to party right about this in the Washington examiner he's a resident fellow at the American enterprise institute the author of a book called alienated America Tim Carty welcome to candle wax our you doing well how are you doing I'm good I I approach the you know the information about the lab with caution but as you point out in the piece it would maybe be irresponsible to at least not look at this and what happened in this lab considering via the fallout globally right now so what what do we know about what happened in that lab well we know that it was a lab that investigated among other things corona viruses now did I mean that corona virus we never use the word before the spring obviously but scientists Dr is that the words for all a whole family of viruses that include the common cold and they are so this was a lab that investigated those investigated those that originated in the back as well and most scientists actually agree that the the corona virus sweeping the world right now the pandemic is one that probably originated in a bat the other thing we know about this lab is that when C. U. S. state department officials visited there because they said that the security the safety the cleanliness all of that was not what you would want from people who are handling a very contagious virus and very contagious diseases and so all of that adds up to sanction I wonder if some of the work the scientists were doing there is still some sloppy action the virus came out of that laboratory and ended up infecting somebody in will on now it in again you point out here you're not saying that it was made in this land right back right now that's that's your thing that's an easy confusion to make if you say that seem out of the lab that can sound like it was made in the lab and in our editorial when we say investigate the lab what we're suggesting is that it rather than some guy who bought a pangolin that had been cooked on buy it back that might have been how it happened but it also might have been that is the is research facility which again was noted to have so the poor safety techniques and methods that this research facility allowed it to escape why is that important because China's government has steadfastly denied it and if this is a government lab if China's government through its own sloppiness let this out and then lied to the world about it well that would tell us a whole lot more about well about a Chinese state but it might also be able to tell us something about the nature of the virus we're conducting experiments on it they might know more about it will be out to if Saddam assigned to share might be able to know more about it than we do now when you say pangolin that's the that's sort of the anti that's that's like an ant eater right that's the connection to the back that's that's that's gets worked with scientists basically say you know I think the the sort of the gas of the sort of natural way but the virus enters the human population with somebody bought either eight or touched a pangolin which is a scaly little it looks like it's an acorn and an anteater had a baby what it does here it's very prehistoric looking bizarre now it it does seem like you want to time that somebody bought something like that which is a very rare animals sold in some of these markets and in China and that bad bad bad bad tangling have probably been infected by it that that's the best gas that scientists looking at the DNA X. cetera are are making right now and this is all going to be guess work because this is our first time encountering but again there's a possibility that if that if there were experiments done on this particular strain of coronavirus if that were shared with more of the world then we would be able to better fight than we are now all right so let's let's kind of stipulate that were operating from that perspective and say yeah this is certainly worthy of an investigation but how with the Chinese in particular we move forward and get real answers that you can trust well that's that's a very good point because this is every game that is famous for covering up and so we certainly don't believe that it would be as easy as the F. B. I. showing up in you know going through the at the cash register of the a mop around troops store or something like that their ability to cover up their ability to completely deny anybody from outside their government to inspect would be pretty strong but right now the simple demands that there be an investigation trying to pressure the W. H. O. to ask for an investigation using diplomatic pressure to press on investigation board at least reveal a little bit of where the Chinese government St Thomas and it's possible that we could do an investigation and just getting bad off the hook or maybe it was not even sloppiness but just the sheer bad luck accident that had to happen and it wouldn't even be China's fault but it still could tell us something about it or if we knew we came from a particular animal that could also tell us something the closer we get the more we get in Wuhan whether it be in the wet market or the lab the more we know about it is right I mean think about all the things that are mystery about this paper saying it cannot do as well in the hot weather maybe if they're different strains of it maybe yeah a lot of I think you're right types of people and so the more we know about it the better we can

"carty" Discussed on Biz Talk Radio

Biz Talk Radio

02:46 min | 1 year ago

"carty" Discussed on Biz Talk Radio

"Is filled with not in it so Carty on health none of them seem to know what it's so great to have used to help Michael how are you good thanks a guardian regarding on guardian okay Carty RD one make sure people fight so let's talk to us you have thirty years experience in building businesses privately held publicly traded on the server talk to us about how you ended up here and talk about the company well this is a passion of mine off to my lost rodeo which was a public company and because I had a lot of times through a non compete that I wasn't supposed to get back into business but my dad had with macular degeneration so my guess is my to I've always had a passion for full health sciences and so I was very fortunate that I was in an area I used to walk every morning with a of tonic scientist we walked five days a week every morning you got some education and I go to the doctor cannot believe and but and that was the beginning there was in two thousand and nine when the company was first formulated and the rest is history I can tell you that my father who is still full you know want vinegar at ninety one years old suffers from this disease and there is no there there is a huge unmet medical need there isn't any effective nutritional tree treatments for it it's all medicinal talk about you know glaucoma talk about this disease in particular because if you if you have any dry macular degeneration is not a fun thing for some to have to go through to talk about that so to understand macular degeneration correctly with macular degeneration comes off the dry macular degeneration people should know that you don't just get with macular degeneration but when you have dry macular degeneration it is actually something you can do about it okay and it is nutritional really it's now becoming front and center with all the clinicians and there is in your eye there's something called the macula protect the pigment in your eyes in your eyes which is right rising lies right over the Soviet getting too technical now that I've never jog my that's that's you were you were you get your central vision and what it is like it looks like your internal sunglasses basically okay and it still does not only damaging oxidative blue lights in the axes it acts as a protector of the redness now as we get older and as things normally happens when you get older you lose the the the density of immaculate pigment the macula protected pigment has become a very important biomarker full full that's.

Carty Michael scientist
Kanye West Held Sunday Service At Bayfront Park

All Of It

00:57 sec | 1 year ago

Kanye West Held Sunday Service At Bayfront Park

"Like Kanye west performing some kind of church service in in downtown Miami in an open empty theater that's right and at bayfront park Connie west brought a choir invited a pastor from a local church that actually married him and Kim Kardashian west to to calm and give a sermon and they played these are gospel a remixes of his music and other pop music from the last several decades and just a very Miami moment and you've been there covering it also have you rub shoulders with any famous celebrities over the last few days we've been reporting on sightings all over town folks like Bryan Cranston and Aaron Paul from from breaking bad rap stars playing in Miami gardens Carty B. and DJ Caledon JZ arriving at the stadium in Miami is a nexus for for Hispanic music for hip hop music for for a lot of celebrity and so I think the Superbowl kind of amplifies you know of five that's already there

Kanye West Miami Kim Kardashian Bryan Cranston Aaron Paul Dj Caledon Jz Bayfront Park Connie West Miami Gardens Carty B.
"carty" Discussed on Z104

Z104

15:44 min | 1 year ago

"carty" Discussed on Z104

"It's could lead some house he was stopping his ego Carty be Hampton Roads number one hit music station Z. one oh four he had a black on black have you been all about them nobody right and about it two thirty here in the mornings on this money January six morning and welcome back everybody if you get back from holiday break you got sunny in fifty five today and then tomorrow we'll be back in the mid fifties by this weekend seventies yep believe it or not so you have that to look for two so seriously take your tree down we're trying to tell you doesn't make it with your friends and this is a major give me it is yeah as did you get your name from you thank you for having now do you think of me I Trina that's been to see one for a she is that you planted in click so D. I got a you just hook it up the line known talking seventeen only because you know you you want to freaky sweet sweet get a the scene was so please take a he sees what I am trying to get see please I justice so this she says you can see what changes this yes just as Japan with the baby laid out with because the girls will whether yeah you'll really want to chance go back and see what a mess so black laugh that will not be yeah cancel my vacation so you have yeah you for free so you want to so please well the AP wire at users bring with me a once upon a time in Hollywood maybe three hours long Leonardo DiCaprio attended the premiere of by the end is that I was too old for it your ray is hosting the golden globe awards last night and yes he was off the chain I mean like even though everything back last night I think there was so much of it the one thing that I kind of was like it was kind of like funny but it seems I'm like kind of like a scratch may going he's right he said you're fired Kevin Hart for some offensive tweet and then he goes I like all the ways of the golden globe awards were last maybe you fell sleeping or you didn't watch of forgot about it will cover that coming up this morning for it's Monday January six with the mortgage you I Nick that shaggy was up and actually is off to you should be back tomorrow don't worry about that partly cloudy hi from fifty five right thirty eight right now so it's a little chilly out there this morning coming up for you this week on the show free money now you're back to back in work mode you spend all your money over the holiday break in your broke we get it so about a thousand dollars starting every hour at eight AM first chance we're calling instagrammed that makes sense right so your first chance quite a bit to eight o'clock we've the first key word so playing your morning run its telephone alarm or something so you ready eight o'clock here that key word also we got auto issue tickets that's this weekend you know we've got admirals tickets this weekend as well we'll have that for you up for grabs we've got to bring the war the roses coming up this morning around eight o'clock as well plus is you said the golden globes to winners the surprises and the moments that maybe you missed the people are gonna be talking about that are trending this morning a Twitter will cover that for you so you don't feel like you missed anything this morning plus if you ever latest rumor about Lori Laughlin eight K. out Becky it's crazy it's right out of a movie to be honest with you plus a dell people are starting to say now that she's losing too much weight is there a middle row I don't know Khloe Kardashian would not start twenty twenty bike taking back cheating Tristan Thompson would she says are because of some tweets she posted people think she is also you've heard of breaking and entering before how about breaking entering and sucking it yes it's a brand new crime that we can't wait to tell you about this morning speaking of crimes you would call the cops if you heard this coming out of your neighbor's house rent yeah probably Hey it's not what you think it is and it's not the other thing you could get is either we'll talk about that this morning plus one of the top words slash raises the need to go in twenty twenty how a guy who manages Cape prison forty years ago finally got caught in an uber driver story that is so good should probably be a movie all that and a lot more on this Monday morning we get started with you know two or he's coming Saturday March fourteenth eight PM at the Hampton Coliseum.

Carty
NH Man Pleads Guilty To Double-Voting, Loses Right In His State

WBZ Midday News

00:39 sec | 1 year ago

NH Man Pleads Guilty To Double-Voting, Loses Right In His State

"The New Hampshire attorney general's office says a man accused the voting in the state after voting in Massachusetts during the November twenty sixteen general election has pleaded guilty eighty one year old Charles card here of Madison New Hampshire has lost his right to vote in New Hampshire Carty was arrested last year and charged with knowingly casting ballots in both Madison New Hampshire and Attleboro Massachusetts he pleaded guilty in Carroll County Superior Court on Friday he was sentenced to sixty days in jail all suspended for one year on the condition of his good behavior he also was fined over a thousand

New Hampshire Massachusetts Madison New Hampshire Superior Court Attorney Charles New Hampshire Carty Carroll County
Lizzo named The Associated Press' Entertainer of the Year

AP News Radio

00:34 sec | 1 year ago

Lizzo named The Associated Press' Entertainer of the Year

"Liz always dominated the pop our indie and rap chart with truth hurts and because I love you it's all coming six years after release of her first album and he's received praise for her live performances lives there was a leading contender in the upcoming Grammy awards he has eight nominations outside of music Liz has won over fans for promoting body positivity and denouncing fat shaming Liz though is branching out with the role alongside Jennifer Lopez Carty be in the movie hustlers the entertainer of the year votes come from the AP entertainment staff I'm a Donahue

LIZ Jennifer Lopez Carty Donahue Grammy AP
"carty" Discussed on KROQ 106.7FM

KROQ 106.7FM

01:39 min | 1 year ago

"carty" Discussed on KROQ 106.7FM

"You're you're you're doing a Carty be line right there yeah I get lines let's answer to it is what we're saying you guys remember when mugs told us that you shouldn't use your heat at night because you'll die for ER room in our part of an oxide which whatever yeah yeah proven wrong yeah but that there was a problem in the past yes it could happen but he learned it from his father that was born I believe the war of eighteen twelve is when he was conceived the tough time here's the thing I I mentioned how I never have the heat on at night I can't sleep without on I need a colder room when you sleep well because so many people want to crank up there he they're saying don't do it right before bed sleep expert James Wilson says it's better let your bedroom get a bit cooler before turning in for the night because it encouraged encourages the body to drop to the core temperature needed to fall asleep successfully so may not even colder for awhile older a lot of people think oh no I wanna be cozy and warm then I'll be all snuggled up and fall asleep no it takes your body longer to fall asleep when your warmer greeter sting I I knew this could ask me I did not yeah a festa do you go by James Wilson sleep expert yeah I have yeah in the past yeah it's a it's an alias yeah another expert warns that leaving the heat on all night can leave you thirsty suffering from dry mouth and you wake up dehydrated which makes you more prone to infection we should do is drink water can't drink water while you're sleeping helps if you're hydrated I think that's an issue but also turn your heat off and then you won't be as.

Carty James Wilson
"carty" Discussed on KIIS 102.7

KIIS 102.7

03:53 min | 1 year ago

"carty" Discussed on KIIS 102.7

"Ten a post Malone Carty be arrested writing on the wall number three we can see because three weeks three weeks Jo Jo on the radio six you will want to set five memories number he is doing do you ring the bell the memories of everything we've been through the Jews bring and.

Jo Jo Malone Carty three weeks
Cardi B joins the cast of 'Fast and Furious 9'

10 10 WINS 24 Hour News

00:21 sec | 1 year ago

Cardi B joins the cast of 'Fast and Furious 9'

"Fresh off her role in hustlers Carty beat to appear in universal's fast and furious nine we know this because vin diesel made the announcement on Instagram with a video that showed the two of them on set on one so on the last day of filming in the U. K. all low all no word what role Carty plays in the film

Carty
"carty" Discussed on Z104

Z104

03:18 min | 1 year ago

"carty" Discussed on Z104

"Weekend plus coming up in each of the city we have a lawsuit to talk about the loan I sexing Carty be it still somewhat the one there is a good idea.

Carty
Travis Scott unveils Netflix doc 'Look Mom I Can Fly'

Big Boy

00:28 sec | 1 year ago

Travis Scott unveils Netflix doc 'Look Mom I Can Fly'

"Fan so Travis got recently dropped his new Netflix special documentary which you should definitely watch what my can fly and in there they have behind the scenes look of the night of the Grammys and as you know astroworld went up against invasion of privacy Carty be won that award and he did it now when you watch it yeah you've got emotions in there you're rooting for Travis the entire time you like all that way and it's a great album as he showed you every being like the recording them

Travis Netflix Carty
"carty" Discussed on Z104

Z104

03:26 min | 1 year ago

"carty" Discussed on Z104

"On the Z. Carty being who apparently does not like the NYPD and Taylor swift yes she has a plan to get her own music back and it probably won't work right now I just need you to get real loose so they're at now take a faint little years this next the rats who have a good time due to but Hugo time this take it take it down now bring it bring it up yeah right here due to it was not so bad that would that wasn't so bad that was not so bad that was so bad was it it was not so bad that was so bad it was not so bad that was so bad it wasn't going to do it it's well the no you can't yes three on.

Z. Carty NYPD Taylor Hugo
Simone Biles makes history with a "triple-double"

The World

03:09 min | 1 year ago

Simone Biles makes history with a "triple-double"

"City gymnasts Simone Biles had looked as one commenter on Twitter put it a quiet talk with gravity Biles landed a triple twisting double for what's known as a triple double and it's the first time a woman has done so in competition among those watching Simone Biles make history yesterday it was NBC sports reporter at Nixa Carty he joins us now head neck thank you for having me on I feel like we should begin by noting when we say she landed at I mean it looked pretty perfect I've had it on repeat on Mike her whole working it was beautiful there was the epitome of what Simone Biles is the height the power and the clean execution there's nobody else that I can do that skill at all and certainly no we can deal with that sort of precision if they try and just explain briefly for that lay people out here what is a triple double what exactly is it that she managed to do yesterday to basically coming up in the air and in the air before coming down she is doing three twists while flipping over twice so that's what the name triple double comes from no other woman has done it some men have done it but very few she's obviously an incredible role model for younger gymnasts coming up behind her in competition she's also been outspoken and public about being a survivor of Larry Nasser than former USA gymnastics team doctor who's now behind bars for sexual assault she has been vocal about sizing USA gymnastics for the way they handle that and other things it gave me speak a little bit about just what her role is in the sport beyond whatever you know beyond this incredible achievement on the floor yesterday that's what I think makes this come back for Simone so special is that she's not only shown that she has better gymnastics skills and she did before but she is coming back a time where there is so many troubles associate with their sporting mention the Larry Nasser scandal and everything this happened with USA gymnastics she has taken that head on she came forward as an access provider in January twenty eighteen and she's only since then in interviews spoken up and spoken loudly in criticizing USA gymnastics shortcomings with all their leadership changes she's been careful about it about how everything's a factor and how she goes to you know get checkups with physicians or physical therapist and she still you know little has a ten which you obviously you can imagine and to deal with all that at twenty two years old and still go out and dominate more than ever before it's just speaks to her mental resolve wow so I mean what are you looking for we sit too early to start laying bets on what might happen in twenty twenty in Tokyo I mean is she is more dominant over in the United States field and the world field now than she was at this point the last Olympic cycle when we were one year before Rio after taking a year off to be able to get back to a level better than you were before at an age where Jim the so usually deteriorating at this point she's a favorite for not only won two gold medals but for five she won form real I think she

Simone Biles Twitter Twenty Two Years One Year
Carty, Indianapolis And One Day discussed on WBZ Morning News

WBZ Morning News

00:26 sec | 1 year ago

Carty, Indianapolis And One Day discussed on WBZ Morning News

"Carty be cancelled a concert in Indianapolis last night less than an hour before show time because of some kind of security threat the concert has been rescheduled for September eleventh fans disappointed I hope this here one day but probably not September eleventh just saying I formally police say the threat was on verified and not a public safety

Carty Indianapolis One Day
Senate, Carty B. And Bernie Sanders discussed on 10 10 WINS 24 Hour News

10 10 WINS 24 Hour News

00:21 sec | 1 year ago

Senate, Carty B. And Bernie Sanders discussed on 10 10 WINS 24 Hour News

"Well she had this to say on Instagram when it comes to the Senate seems Carty B. has made her pack she teamed up with Bernie Sanders for a video on issues of concern to millennials including student debt and minimum wage for his part Sanders told Jimmy Kimmel the card is really smart and he's delighted that she's a

Senate Carty B. Bernie Sanders Jimmy Kimmel
Beyonce, Google And Carty B. R. Grande Halsey discussed on The Lake Show with Henry Lake

The Lake Show with Henry Lake

01:46 min | 1 year ago

Beyonce, Google And Carty B. R. Grande Halsey discussed on The Lake Show with Henry Lake

"Well Arianna Grande killers one day yeah yeah yeah she's a girl top of the MTV VMAs Beyonce's My Girl Beyonce's your girl early the list of the top nominees for the MTV video music awards the just the pop music is the farthest thing from the dude ranch now of course because it will not sex and the horse he rode on Billy ray Cyrus ereli they've got the something about an old town in a road or something like our room I don't I don't my nine year old loves it she's got like the whole dance down and I'm like I have to Google the words I don't even know what that means but apparently apparently that's the thing but I tell you what I mean Taylor swift will not sex I don't think they're even in the artist of the year category which console I really okay I kind of surprises me I think it's Carty B. R. Grande Halsey who seems like all these kind of the it girl right now too and she I'm not really hip on our music to be honest with you yeah full transparency but in the best new artist low NAS axes in there as is list so she is very she's represent me she's got the the law did get will she she's talking about the Vikings and all that because she spent some time in Minnesota so she cannot represent a little bit here in regards to the six you're not originally from Minnesota but she spent time here in lived here so a lot of people are excited for her but yet via the VMAs always something that we all pay it a lot of attention to what some of us anybody anybody that love to claim that they're from Minnesota even if they're not from here give me up you want to be one of us you're one of us they spend time here

Beyonce Google Carty B. R. Grande Halsey Vikings Minnesota MTV Billy Ray Cyrus Taylor Nine Year One Day
"carty" Discussed on AP News

AP News

02:37 min | 1 year ago

"carty" Discussed on AP News

"The Carty and the bad device are trademarks pretty limited the card cable Florida run forty percent alcohol by volume Facebook plans to launch a new digital currency but as the AP's at Donny reports it's making some senators nervous to grill the company on Capitol Hill the new currency is called libra wouldn't it be easier and safer if people could securely and inexpensively receive money transfers through their smartphones Facebook's David Marcus says he wants the US to be a leader in digital currency but the company is still dealing with privacy issues Facebook is dangerous Ohio Democrat Sherrod brown says Facebook moved fast and broke political discourse move fast and broke journalism surely they don't respect the power of the technologies they're playing with like a toddler who's gotten his hands on a book of matches Facebook is burned down the house over and over David Marcus says Facebook will take the time to get this right and Donahue Washington Cambodia's government says plastic waste shipments sitting in a Cambodian seaport came from the US and Canada Cambodia's environment ministry said almost seven dozen shipping containers were found to be filled with plastic waste a ministry spokesman says the total weight of the waste which was discovered on Tuesday with sixteen hundred tons the cross border disposal of waste became a major regional issue after China barred imports of almost all foreign plastic waste early last year we shipments have sinned shifted to other countries including Indonesia Thailand and Malaysia which also started rejecting shipments the ministry spokesman for the government committee established to look into the matter will investigate how and why the containers ended up in Cambodia a major terrorist is been made in Pakistan A. P. isn't Charles bill does more reports of forties have in custody a U. S. wanted suspect in the two thousand eight Mumbai attacks Pakistani authorities say they have arrested a radical cleric and US wanted to terror suspect blamed for the twenty oh eight Mumbai attacks in India just days ahead of Pakistan prime minister in run call on this trip to Washington leading Pakistani counterterrorism official says hi fi society was taken into custody in Punjab province well he was traveling from the whole he said so I eat has appeared before a judge and was ordered held in jail until the next hearing I'm Charles sort of this month radio why president trump continues his attacks on for first term house Democrats for the hate filled extremists.

India president Charles Punjab Mumbai Pakistan Indonesia Canada Sherrod brown Ohio trump official Washington prime minister Carty Charles bill Malaysia Thailand China Cambodia
"carty" Discussed on Power 106 FM

Power 106 FM

02:14 min | 1 year ago

"carty" Discussed on Power 106 FM

"You thank thing we're not talking about you got a call singles are worked out yeah that was the two thousand and Hey I think I've been in the strip club maybe talking to minutes out let's go check you might cause the DD from corona DD was going on well good morning good morning we're in the middle of court right now and I'm trying to represent my client Carty be guilty or anything I email are you always be compared you know well there would be a what do I was talking about different things thank right unfortunately in this day and age thank but not like you have made the status it came in now is the double standard you're you're absolutely right now so I'm just trying to wreck but of women one time just say sometime JD I which I love I love him as a friend of mine but I think it was a little out of line just just categorizing women he was doing exactly what he was talking about by just saying all this is all there rapping about no that's not a can you not like let me in by one I'm I'm guilty of that thank you so that you thank you because of the also you have the card in the South Bay all right I think I'm ready to make my decision thank you to all soul and mind full of male rappers is very big and so we do have love dogs and now we have the people who too bad you know the the good stuff we noticed that the female pool is smaller and so when he says that they're not rapping about anything else is that maybe we should have some diverse city so it is needed I think that's all he was trying to say you're I hear I hear you prosecutor ninety you counsel.

Carty South Bay prosecutor
Carty B. discussed on Wayne Cabot and Paul Murnane

Wayne Cabot and Paul Murnane

00:19 sec | 1 year ago

Carty B. discussed on Wayne Cabot and Paul Murnane

"Carty B. is celebrating your daughter's first birthday by releasing a song about her one called the hunter music aficionados out there will recognize this speech from the nineteen ninety nine single love is blind Carty be thank the artist you for giving her the green light for

Carty B.
Don Carty And Rhode Island discussed on Ron St. Pierre

Ron St. Pierre

00:23 sec | 1 year ago

Don Carty And Rhode Island discussed on Ron St. Pierre

"Following pro-life advocates lamenting the passage of an abortion rights Bill, which was signed into law this week, they gathered today to discuss their concerns with the law, which supporters say, protects abortion rights in Rhode Island. No matter what may happen at the federal level among those speaking out. Former governor Don Carty ARE who says abortion is an abomination in that life is an absolute says, too many people in the state have lost their moral

Don Carty Rhode Island
"carty" Discussed on Power 105.1 FM

Power 105.1 FM

02:43 min | 3 years ago

"carty" Discussed on Power 105.1 FM

"Don carty be kodak yellow dan ma news team now demi more onboard now i am sitting down with them neon bowl eilat jose malone brock's dr manet i'm a little i remember above improvement on futures i go rockstar dj kenner we honor and rising to live vile thoughts wow when i would find out who we did the iheartradio sunday march eleven gbs tnc andrew tv in here all too nominees now on iheartradio use award station powell 105 was close and charlemagne the god warning everybody is dj mg angel ye shall amina guy we are the breakfast club now we have a special guest joining us a she's a actress producer and screenwriter we have ms lynne away in a building were i thought lena last night she asked me she said now heavily actually seen have you probably not if we have seen it all guys at the gym training and much i was like i got to check out the shot and i'm like why he was like charlemagne postponed is this agreed that immediate crowd lubitsch so he was that i've got to go said yes the mission was on with me cry twice in one shot i had to say so i i watched it did you like it i love that action i'll thank you very very did you pulse about it no i didn't pull pulse about it imposed we had a stick together on imposed by wackos we have ruled the mine emma house that i can't watch the show without my wife and i watched do without my way okay and it'll be destruction in my here's the deal to my wife and i can this would i need to know yet lease on watch it together okay all right and then bogota tweet about it okay your gums about it knew that i appreciate that tweeted about and that's how we guy jason mission to come on the run angela appreciate jerry was great and then handke's my shot and i said we love to have come on up years worked out as marble louis the operator of the show right leaner live here the first black woman to win a of emmy for comedy writing correct said yeah it's kind of crazy told me last night and you want to be to konya west of writing yeah yeah i think because i think my mission is to.

Don carty andrew tv powell producer lena charlemagne jerry handke amina bogota jason mission konya eleven gbs
"carty" Discussed on Power 105.1 FM

Power 105.1 FM

02:43 min | 3 years ago

"carty" Discussed on Power 105.1 FM

"Don carty be kodak yellow dan ma news team now demi more onboard now i am sitting down with them neon bowl eilat jose malone brock's dr manet i'm a little i remember above improvement on futures i go rockstar dj kenner we honor and rising to live vile thoughts wow when i would find out who we did the iheartradio sunday march eleven gbs tnc andrew tv in here all too nominees now on iheartradio use award station powell 105 was close and charlemagne the god warning everybody is dj mg angel ye shall amina guy we are the breakfast club now we have a special guest joining us a she's a actress producer and screenwriter we have ms lynne away in a building were i thought lena last night she asked me she said now heavily actually seen have you probably not if we have seen it all guys at the gym training and much i was like i got to check out the shot and i'm like why he was like charlemagne postponed is this agreed that immediate crowd lubitsch so he was that i've got to go said yes the mission was on with me cry twice in one shot i had to say so i i watched it did you like it i love that action i'll thank you very very did you pulse about it no i didn't pull pulse about it imposed we had a stick together on imposed by wackos we have ruled the mine emma house that i can't watch the show without my wife and i watched do without my way okay and it'll be destruction in my here's the deal to my wife and i can this would i need to know yet lease on watch it together okay all right and then bogota tweet about it okay your gums about it knew that i appreciate that tweeted about and that's how we guy jason mission to come on the run angela appreciate jerry was great and then handke's my shot and i said we love to have come on up years worked out as marble louis the operator of the show right leaner live here the first black woman to win a of emmy for comedy writing correct said yeah it's kind of crazy told me last night and you want to be to konya west of writing yeah yeah i think because i think my mission is to.

Don carty andrew tv powell producer lena charlemagne jerry handke amina bogota jason mission konya eleven gbs
"carty" Discussed on Power 105.1 FM

Power 105.1 FM

02:43 min | 3 years ago

"carty" Discussed on Power 105.1 FM

"Don carty be kodak yellow dan ma news team now demi more onboard now i am sitting down with them neon bowl eilat jose malone brock's dr manet i'm a little i remember above improvement on futures i go rockstar dj kenner we honor and rising to live vile thoughts wow when i would find out who we did the iheartradio sunday march eleven gbs tnc andrew tv in here all too nominees now on iheartradio use award station powell 105 was close and charlemagne the god warning everybody is dj mg angel ye shall amina guy we are the breakfast club now we have a special guest joining us a she's a actress producer and screenwriter we have ms lynne away in a building were i thought lena last night she asked me she said now heavily actually seen have you probably not if we have seen it all guys at the gym training and much i was like i got to check out the shot and i'm like why he was like charlemagne postponed is this agreed that immediate crowd lubitsch so he was that i've got to go said yes the mission was on with me cry twice in one shot i had to say so i i watched it did you like it i love that action i'll thank you very very did you pulse about it no i didn't pull pulse about it imposed we had a stick together on imposed by wackos we have ruled the mine emma house that i can't watch the show without my wife and i watched do without my way okay and it'll be destruction in my here's the deal to my wife and i can this would i need to know yet lease on watch it together okay all right and then bogota tweet about it okay your gums about it knew that i appreciate that tweeted about and that's how we guy jason mission to come on the run angela appreciate jerry was great and then handke's my shot and i said we love to have come on up years worked out as marble louis the operator of the show right leaner live here the first black woman to win a of emmy for comedy writing correct said yeah it's kind of crazy told me last night and you want to be to konya west of writing yeah yeah i think because i think my mission is to.

Don carty andrew tv powell producer lena charlemagne jerry handke amina bogota jason mission konya eleven gbs
"carty" Discussed on Biden's Briefing

Biden's Briefing

02:10 min | 3 years ago

"carty" Discussed on Biden's Briefing

"Ace celluloid and houstonbased beligum pharmaceuticals silly add recently started a trial of its car carty and colorectal cancer belgium miss testing it's carty and pancreatic tumors and is told investors to expect initial results in 2018 juno plays catchup in carty 2016 was a tough year for dzhuna therapeutics which was once considered a leading player in carty then was sidelined by side effects seen in its trials but the company showed signs of life in 2017 most recently in december when it presented data from a trial of its leading car t j car seventeen in patients with aggressive bcell nonhodgkin lymphoma those data stacked up well against other carty treatments a sixty eight percent complete response rate and a relatively low rate of side effects june on his promise to file for fda approval in the second half of 2018 investors are still nervous the stock is taken a dip in the past month but shares have doubled since the start of the year in anticipation of a comeback on collided viruses pick up steam many viruses have a natural ability to kill cancer and several companies have been working on engineering viruses to target certain tumor types antigen won the first fda approval in the space with its on kalinic virus mlive jake and engineered form of herpes in melanoma the field has been relatively quiet since then but is expected to pick up some momentum this year among the on kalinic viruses generating excitement recently is uk based sileks is therapeutics which has partnered with bristolmyers squibb to develop an armed form of ad no virus the therapy called n g three 48 uses the virus to transport to therapeutic genes directly into tumors in the hopes of recruiting immune cells to attack the cancer in december the company announced it is getting ready to start human trials in solid tumors prompting a fifteen million.

carty cancer solid tumors dzhuna fda uk sixty eight percent
"carty" Discussed on a16z

a16z

02:02 min | 3 years ago

"carty" Discussed on a16z

"Sell engineered cell therapy approved and carty historically you know fda risk or regulatory risk was really used as this barrier in this essentially fear factor but i think as the therapies become more powerful as we target things were we understand fundamentally what's driving the disease biology and therefore understand fundamentally how best to intervene i think what becomes pretty clear that regulatory risk in many ways was just a euphemism for scientific risk for experimental risk gene therapy an area that historically has been considered to be very risky has been shown to be so effective in this form of treating inherit a bull form of blindness that that passed the fda panel recommendation unanimously the thirteen deserve vote car t similarly also passed the fda panel at a thirteen deserve vote i mean those are two things that two modalities to therapeutic modalities to treatment modalities that were considered to be very very risky but they were shown to be so effective that that sort of risk goes away and i think when we see a lot of these therapies emerging the benefit the effect is so powerful that it's very clear that the therapies work and therefore the regulatory risk is low so traditional therapeutics companies ghana market through a regulated process of clinical trials and they've kind of look the same way for quite a long time as we see this new type of baiocco many will will does look any different there are emerging technologies that are going to change the way we think about testing and ensuring that our drugs are safe and effective so just to take a step back in history or at least to where we are today even the way we ensure a drug is safe and effective his first we determine whether or not we think a drug might work and the way we do that is by tested in animal models and cells in the petri dish and once we convinced herself that drug might be safe and might be effective in those models we then go to human clinical trials were we of course need human volunteers to confirm that the drug is in fact safe and effective.

carty
"carty" Discussed on Start the Week

Start the Week

01:59 min | 3 years ago

"carty" Discussed on Start the Week

"And you argue that actually if we really understood modern science more more deeply on better than we would get a sense of all from signs not from religion well i don't i don't i don't think i say any way that we wouldn't get it from religion i what i hope to explore and to share is a sense that wonder in some sense that state of being that state of mind is at the root of philosophy that's what what plato and aristotle star with that philosophy starts in wonder but it's also the root of many cultural activities including religion and science as a cultural activities i wonder if you like as the is the source of many many kinds of human flourishing and science is one of the biggest in our time it that's where the money goes a lot of it goes towards destructive applications but much of it also goes to create extraordinary artifact which in some sense one could compare in their cultural significance to let's say medieval cathedral you can think of those in was telescopes in the outcome a desert bringing us pictures of galaxies with a carty we've never seen before an extraordinary beauty and they are great cultural achievements and their another way of finding wonder the importance of the word as in the dna code of human beings for instance it's another kind of writing yes i suppose it is i mean there's there's great wonder in in getting trying whether one has had the training or not in in trying to get to grips with what we can learn about the nature of human being from our dna we can none huge amount but we also learned that there is a vast amount we can't begin to learn from just looking at dna and it's just one one of many levels in which we can explore and deepen our sense of what it is to be alive as he saying this very brief the time we have indeed the dynamism of you book comes from your could of exhuberant sense with delight about many of the things that we are just discovering at the moment for instance let's talk about sound waves in the brain i was made by this.

carty
"carty" Discussed on The New Yorker Radio Hour

The New Yorker Radio Hour

02:13 min | 3 years ago

"carty" Discussed on The New Yorker Radio Hour

"We should listen to vote at kelo did some good stunned and caused the student housing student june brad nitz says let's not forget about forty percent of this on the radio dix like so carty gray s from the south bronx and she is really interesting because she did not become famous as a musician she became famous on instagram and vine in two thousand thirteen early two thousand fourteen why at first she was just another girl who is making funny videos that people used as memes as response gifts that kind of thing but then she actually started building her own following and that's because she's stressed a miracle of streaming but akyayla was supposed to introduce s taccardi be but it ended up being a blockbuster it's the music story of the year i think that a lot of industry people aren't they aren't sure of how to integrate streaming into the way that we understand what listeners are into the cardi be has shown us that's where the money is and that's how you create a community of people who are willing to you know build your profile in a way that is nearly unpacked unprecedented i'd say in you and so now we we make a rapid transition from cardi b two what what else it would spin off we should talk about chopped junior loves his as she does maybe you now a bit of i give her a slightly despairing the secret watching it i have to it so top junior has same pat premise as the original chopped which has to say there are three rounds in which four contestants have to make an appetizer and main and the desert from four random ingredients as a chili peppers vanilla ice cream makes odd dog and something at in like sardines ya.

kelo brad nitz instagram carty gray forty percent