35 Burst results for "Carl I"

Doctors grow frustrated over COVID-19 denial, misinformation

AP News Radio

00:55 sec | 2 weeks ago

Doctors grow frustrated over COVID-19 denial, misinformation

"The mood has changed for many healthcare workers during the pandemic people are behaving badly a year ago we're you know health care heroes everybody happened since now are being in some areas rast doctors do Kaufman works in an emergency room in Dallas in baton Rouge Dr Vincent Shaw is hearing doubts about the vaccine most common as I'm not sure what's in the vaccine Dr Carl Lambert at rush medical university center in Illinois says he's hearing downstairs that ship in the vaccine that it takes over your DNA that it that it gets into your genome which is which is impossible member tries to calm the patient hoping to change their minds even say like empathetically yeah there's a lot information it's easy to get confused but I'm so glad you brought it to me so that I can can kind of clear that up one patient told the doctor he wanted to strangle president Biden for pushing for vaccinations I'm at Donahue

Dr Vincent Shaw Dr Carl Lambert Rush Medical University Center Kaufman Baton Rouge Dallas Illinois President Biden Donahue
Biden Administration Reviving Trump's "Remain in Mexico" Border Policy

The Larry Elder Show

01:25 min | Last month

Biden Administration Reviving Trump's "Remain in Mexico" Border Policy

"I welcome back to the larry elder show. I'm here with my guest. Baena the meal. I'm carl jackson here. What my guess. Horry baena the media research center latino just real quick or hey I just wanted to get your take on this The biden ministration. All of a sudden seem to be cozying up to the or reviving. The trump's remain in mexico city policy. Give us a quick take on that for you. Go well it. Was it foolish for him to to unwind those those policies run but he wanted that on day one At the at the at the request of latino media basically and latino activist immigration activists you know biden unwound these reform the of these these. These measures remain the mexico the mtv program And that basically opened the door and that set an open invitation for basically the central america the empty itself out onto our southern border. I had enough And he got fired of all the winning so to speak trying to reimpose Remain in mexico. I don't know how you gonna do it when you got no mexico. Because when you unwind those agreements those other nations are no longer bound to them. And i'd with mexico so i need do remain in mexico with no mexico.

Baena Carl Jackson Horry Baena Biden Mexico City Mexico America
Don Brown Discusses His New Docu-Drama 'Call Sign Extortion 17: The Shoot-Down of SEAL Team Six'

Mike Gallagher Podcast

02:46 min | Last month

Don Brown Discusses His New Docu-Drama 'Call Sign Extortion 17: The Shoot-Down of SEAL Team Six'

"Had an opportunity to watch a movie that i can't wait to share with you. I've heard dan brown on the radio before great great great patriot a former. Us navy jag. Officer is the author of sixteen fifteen books including call sign extortion. Seventeen the shootdown of seal team six. This was a a nonfiction military. Expose on which this movie fallen. Angel documentary is based A real joy to welcome don brown to the mike gallagher. Show done first of all. Congratulations on bringing this thing to the to the big screen. This documentary is gonna be available at salem now dot com it's produced by rpm films available on our streaming platform. Tell us all about the documentary. What the event was that. That was such a pivotal role in your life. Tell us about. What kind of questions are answered by the movie by the book by the whole process mike. Thanks for having me again. I've been with you before you. You're the great patriot in his our country. So well This this docu-dramas very very powerful docudrama movie which tells the story of extortion seventeen or stores in one seven as they say military aviation parlance which marked the largest loss of life in the history of the american vomited. The war on terror in the largest loss of life in the history of our. Us navy seals. We lost thirty americans at day including uh seventeen members of seal team six and the one of the great tragedies that most americans still don't know about this we know about other things we know about six frivolous soundbites to the liberal media gives us but thirty american heroes lost in one swoop and we still don't know. The story is a general laughing. In this case to filmmakers students. Fiving carl horse are going to do a great great job of bringing this story to light. There are many unanswered questions. You say. I saw a preview on the big screen in the palm beach area. Friday night there was a dry that in see one very powerful expose story and we hope everybody will go on a salem. Now m and wash this move movie immediately in pass on your friends Avid involved in this case for seven years my book came out of in two thousand fifteen year. Kind of to have you on then. Chur cover lots of up a lot of things in this in this story and and the movie touches on some of that No one moving. The one book can tell the whole story but these men need to be honored and this movie is very very powerful. Thing is a great great steps in next step getting their story out. And i appreciate you for Forgiving some time today to remember them.

Mike Gallagher Don Brown Dan Brown Navy Carl Horse United States Mike Palm Beach Salem
Kaley Cuoco Files for Divorce From Estranged Husband Hours After Announcing Split

Radio Surgery

00:22 sec | Last month

Kaley Cuoco Files for Divorce From Estranged Husband Hours After Announcing Split

"Kaley Cuoco and equestrian husband Carl Cook going their separate ways after three years of marriage. They released a joint statement on Friday, saying. While they still have love and respect for each other, they're going in different. Directions with no feelings of animosity or anger, and they won't be commenting further on the matter. It's quote goes second marriage ending in divorce. The news is

Carl Cook Kaley Cuoco
Is Ed Asner in - 'Dug Days' Show on Disney Plus?

Wisconsin's Morning News with Gene Mueller

00:30 sec | Last month

Is Ed Asner in - 'Dug Days' Show on Disney Plus?

"Never died over the weekend. One of his final projects is set to rule out today. Doug Dead Squirrel. The Talking Dog done from up gets his own animated Pixar series, and he's not alone. Get out of my azaleas. Ed Asner is back as the voice of Carl and one of his last performances before his death. Sunday at the age of 91, But it's not his last I m D B list at least seven other projects. Asner filmed her voice that haven't come out yet. All four episodes of Doug Days are out today on Disney. Plus, you didn't dig you, Doug. I am Dog, Jason Nathan's and

Ed Asner Doug Pixar Carl Asner Doug Days Disney Jason Nathan
Trends for Voice Assistants Use in the Car

The Voicebot Podcast

02:27 min | Last month

Trends for Voice Assistants Use in the Car

"All right. So the first thing i want to talk about is how big is this space. So data shows in the us. There are one hundred twenty seven million consumer so that's one hundred twenty seven out of about two hundred sixty million. Us adults who are using a voice assistant at some point while they're driving. Now what does this mean. Let's talk about the definition there. This is the broadest definition of water. Voice assistant use is in the car and that means they could be using bluetooth connected to the sound system it could mean they're using their apple carl carplay or android auto which are projection technologies which basically are just the smartphone but it takes over the screen the payment center screen as well. So it's really that smartphone experience again but it's a little richer than just using bluetooth connect to the phone and then we have the embedded or in car voice assistance provided by the auto manufacturers embedded in the infotainment systems sometimes their custom. Sometimes they're provided by one of the general purpose players like amazon or google so this is the broad definition so about one hundred twenty seven million in the us now. We have three years of data on this from the us around the car. We've been doing this report since two thousand nine hundred. This was the first year we actually added and the uk and germany and the future years. We hope to add a few more as well. So in germany we have twenty seven hundred million. But also you know it's twenty seven million out of an adult population of sixty nine million and then in uk it's just under nineteen million out of fifteen million total population. She's starting to get a sense of how large these these are now the us adoption rates more in terms of people who've tried it. However if you go to the uk in germany what you're gonna find there's a higher proportion of users who are actual regular user so we break this down into people who have occasionally use it. People were monthly active users and people who are daily users so those daily users being the power users using it just about every time they get in the car. So what we see. Is we see a lot more. The casual users in the us a much bigger proportion of the users use it very carefully not in a monthly or daily basis when you move into the uk. Germany they tend to be more monthly active users at least and a lot more daily active user so in terms of the percentage of people were using voice in the car. They tend to be more more to be power users.

United States Germany UK Apple Amazon Google
Actor Ed Asner, TV's blustery Lou Grant, dies at 91

AP News Radio

00:40 sec | Last month

Actor Ed Asner, TV's blustery Lou Grant, dies at 91

"Actor ed Asner has died at the age of ninety one I marches are a letter with a look at his career you've got **** well things worked out differently ed Asner would have been a newsman he studied journalism at the university of Chicago until professor told him there was no money in it as mere is best known role was as Lou grants both on the Mary Tyler Moore show and on the drama Lou grant he was Santa in the film elf and the voice of Carl in the animated movie up as nurse said in a nineteen ninety five a P. interview even if people thought of him as Lou grant he had found his niche in barber's LPAR

Ed Asner Lou Grant University Of Chicago Mary Tyler Moore LOU Santa Carl Barber
Massachusetts Gaming Commission Mandates Vaccines for Employees

WBZ Morning News

00:46 sec | 2 months ago

Massachusetts Gaming Commission Mandates Vaccines for Employees

"Are rolling up again at another state agency, WBC's Carl Stevens, explains. State Gaming Commission executive director Karen Well says, given the evidence concerning the safety of the covid vaccines and the fact that there needed to stop the spread of the virus Commission requirement is in order. I am recommending that we go with the executive branch and says something about the attorney general's branches policy to acquire fascinations of employee expected Massachusetts Gaming Commission. The commission approved it unanimously giving commission employees until September 9th to either show proof of vaccination or to get one scheduled. Then they have to get the shot by October 27th. The commission, which met remotely also voted to fully reopen its downtown Boston office on Federal Street on November 1st.

Carl Stevens State Gaming Commission Karen Well WBC Massachusetts Gaming Commissio Boston
"carl i" Discussed on 990 The Answer

990 The Answer

01:31 min | 2 months ago

"carl i" Discussed on 990 The Answer

"Carl Jackson common name because there's Carl Jackson, Carl Jackson, Carl Jackson and myself, Mr Carl Jackson. I heard about Carl Jackson for years. You know that It was a great son. Clearly a Carl Jackson fan Carl Jackson. Call Jax, Carl Jackson, Carl Jackson, Carl Jack Carl Jackson. Carl Jackson was born and raised in Los Angeles, California, Carl Jackson This journey began at the age of 11. He was introduced. The hard work, faith and family values, however, is a struggling team. He wandered down the path of least resistance, fighting himself, jailed twice and with a child he had to fight to raise by the grace of God. He attended an evangelical church and found that there was a better way. Carl Jackson, there's my hero. He discovered that despite America's flaws, God used our founding fathers to create our constitution. It's divine. An exceptional nature is undeniable. There's just no fake stuff about Carl Jackson, while the seed from South Central is saving California Dangerous out here, Let's roll. Carl. Okay, go dance. A free thinker from Florida is in. Carl Jackson is the reason that I was born. It's the Larry Elder Show with special guest Carl Jackson. If not who Carl Jackson is existence, who you All right. Welcome to the Larry Elder show. The number two called into the relief factor dot com studio is triple 89717243 Triple 89717243. We gotta jam packed Show for you today, Joe Biden's poll numbers are slipping. Obviously, Afghanistan is a big part.

Carl Jackson Joe Biden Call Jax Carl Jack Florida Carl Los Angeles, California South Central California twice today God Afghanistan dot com studio America Larry Elder 11 triple 89717243 89717243 years
US Puts F-18 Jets on Standby in Kabul as Evacuation Chaos Continues

The DeMaio Report with Carl DeMaio and Lou Penrose

00:32 sec | 2 months ago

US Puts F-18 Jets on Standby in Kabul as Evacuation Chaos Continues

"18 jets on standby, Um in the evacuation chaos at the Kabul airport. Major General Hank Taylor. Taylor says the Jets are on standby if the need for air support arises to ensure the safety of U. S troops and operations, video footage and reports of the Taliban stopping people from getting to the airport. When asked about whether the planes would carry out airstrikes. Neither he nor Pentagon spokesman John Kirby, who was nearby provided an answer. 2000 people have been evacuated in the past 24 hours. He avoided a new restraining order filed

Kabul Airport Hank Taylor Jets Taylor U. John Kirby Taliban Pentagon
Dodgers Pitcher Trevor Bauer Has His Restraining Order Rescinded by Judge

The DeMaio Report with Carl DeMaio and Lou Penrose

00:43 sec | 2 months ago

Dodgers Pitcher Trevor Bauer Has His Restraining Order Rescinded by Judge

"Woman. But an L. A Dodger star will not be returning to his team just yet. Despite scoring a legal victory Thursday, we are grateful to the Los Angeles Superior Court for denying the request. Or permanent restraining order. Dissolving the temporary restraining order against Mr Bauer. Trevor Bauer will remain on administrative leave the L. A Dodgers pitchers attorney Shawn Holley, speaking outside of California courthouse after a judge denied a request from the woman accusing Bauer of sexual assault regarding restraining orders. After four days of hearings Now, Bauer was set to come off leave from MLB at the end of the day Friday, but Major League Baseball in the MLB Players Association electing to extend leave for 1/6 time to August 27th. The reigning NL Cy Young winner has been away from the Dodgers since July. 2nd. That's Mount Napolitano, the Dow Down

Los Angeles Superior Court Mr Bauer Trevor Bauer Shawn Holley Bauer Dodgers Mlb Players Association California MLB Major League Baseball Mount Napolitano
California Expands COVID-19 Vaccine Proof Order to Indoor Events of 1,000 or More

The DeMaio Report with Carl DeMaio and Lou Penrose

00:36 sec | 2 months ago

California Expands COVID-19 Vaccine Proof Order to Indoor Events of 1,000 or More

"Change to masks in California I'm Marilyn Hider in the Cove Oh news center beginning September 20th everybody who goes to an indoor event with more than 1000. People in attendance will have to show proof of covid vaccination or a negative covid test within 72 hours of the event. The rules were announced by the state Department of Public Health. The rules previously allowed people to self attest to being vaccinated or having tested negative, But now people will have to show proof. The previous rules also applied only to events with 5000 more people. But the new rules lower the threshold to 1000.

Marilyn Hider Cove Oh News Center Department Of Public Health California
New York Lawmakers to Publish Report on Cuomo's Conduct

Houston Public Media Local Newscasts

00:50 sec | 2 months ago

New York Lawmakers to Publish Report on Cuomo's Conduct

"Lawmakers say they're planning to issue a final report on their impeachment investigation into governor andrew cuomo npr's hansie lo-long reports new york state. Lawmakers recently decided to suspend their investigation after cuomo resigns from office next week democratic governor andrew cuomo had been under growing pressure to step down after an independent report by the new york state attorney general concluded cuomo had sexually harassed at least eleven women. Cuomo has denied any wrongdoing days. After he announced plans resigned on august twenty fourth new york state assembly speaker. Carl hasty democrat said lawmakers will be suspending their investigation. Because new york's constitution does not allow the legislature to impeach and remove an elected official. Who's no longer in office. And a statement hasty says lawmakers will not interfere with investigations by local law enforcement into criminal allegations against cuomo on. Npr

Andrew Cuomo Hansie Lo Cuomo New York NPR Carl Hasty State Assembly Legislature
Cuomo Resigns: What We Know and What's Next

Car Pro

02:06 min | 2 months ago

Cuomo Resigns: What We Know and What's Next

"Was a shocking announcement from New York Governor Andrew Cuomo This week. The three term governor of New York will step down and be replaced by Lieutenant governor Kathy Huckle, despite denying any claims of Sexual harassment. Cuomo said he had become too much of a distraction and wanted the state to move forward. Even as his governorship comes to an end, however, Governor Cuomo could still be facing some legal challenges. Here's a B C's Aaron Carter ski, We went up the mountain. We went down the mountain. New Yorkers flatten the curve. It wasn't all that long ago, Governor Andrew Cuomo captivated the country with his briefings about Covid 19 is frank talk and some legitimate successes bolstered his profile. With success, though, came criticism he killed thousands and thousands of people. Cuomo faced questions about an early decision to return hospital patients to nursing homes and whether his administration later tampered with statistics whether he gave friends and family access to covid 19 tests when they weren't widely available, and whether he improperly used state resources to help him write a book American Crisis. Leadership lessons from the Covid 19 pandemic. State Assemblyman Charles Levine opened an impeachment investigation in the Judiciary Committee into those allegations and the accusations of women who accused Cuomo of sexual harassment. You know when there are two women, there are more than two Charlotte Bennett was among 11 women who state Attorney General Letitia James said she believed when they talked to her investigators about Cuomo's behavior. Governor. Cuomo said his instinct was to fight but at the start of the week his top aide had told him she would resign. And Assembly Speaker Carl Hasty gave Cuomo no way out of possible impeachment. I am not negotiating any deals. On Tuesday, Cuomo announced he would resign the best way I can help now. As if I step aside, he made clear, though he thought the investigation was political and biased in my mind. I've never cross the line with anyone. But I didn't realize the extent to which the line has been redrawn.

Governor Andrew Cuomo Cuomo Kathy Huckle Governor Cuomo Covid New York Aaron Carter State Assemblyman Charles Levi Charlotte Bennett Attorney General Letitia James Frank Judiciary Committee Carl Hasty
Allmendinger Gets 1st Indy Win in Crash-Marred Brickyard 200

AP News

00:43 sec | 2 months ago

Allmendinger Gets 1st Indy Win in Crash-Marred Brickyard 200

"AJ Allmendinger survived a chaotic finish to win the first ever NASCAR Cup road race at the Indianapolis Motor Speedway a loose curbing late in the race lead to a pair of wrecks that took out multiple cars early in the second shoot out chase Briscoe pump race leader Denny Hamlin taking Hamlin out and putting almond digger in front I don't even know like we know showing up the road course races like we can we have fast race cars but like at Indy the way that played out like I mean this is just pure enjoyment it was all men diggers first win of the year Ryan Blaney finished second Carl Lawson was third and leads the Cup points standings Tom McCabe Indianapolis

Aj Allmendinger Indianapolis Motor Speedway Denny Hamlin Briscoe Hamlin Ryan Blaney Carl Lawson Tom Mccabe Indianapolis
New York Gov. Andrew Cuomo's Long Career Ends in Scandal

World News This Week

02:08 min | 2 months ago

New York Gov. Andrew Cuomo's Long Career Ends in Scandal

"York state. Now just days away from getting a new governor after andrew cuomo announced. He's resigning amid allegations of sexual harassment. Questions over his response to the corona virus and looming impeachment. Here's abc news correspondent. Aaron katersky the mountain. We went down. The mountain. New yorkers flatten the curve. It wasn't all that long ago. Governor andrew cuomo captivated the country with his briefings about covert nineteen. Local leadership starts at the top. Is frank talk and some legitimate successes. Bolstered his profile. Welcome governor thank you so much for for being here is our first show back in the studio. Yeah no it's a pleasure. Thank you for having me and welcome back. New york is really opened. Now that you're doing your show with success. Though came criticism he killed thousands and thousands of people cuomo faced questions about an early decision to return hospital patients to nursing homes and whether his administration later tampered with statistics where he gave friends and family access to cove in nineteen tests when they weren't widely available and whether he improperly used state resources to help him write a book american crisis leadership lessons from the cove at nineteen pandemic date assemblyman. Charles levin opened impeachment investigation in the judiciary committee into those allegations and the accusations of women. Who accused cuomo of sexual harassment. When there are two women there are more than two you know we know from experience that it's not just one person and that's why we need to believe every woman who makes these allegations. Charlotte bennett was among eleven women. Who stayed attorney. General latisha james said. She believed when they talked to her. Investigators about cuomo's behavior independence investigation. Found that governor cuomo sexually arrests multiple women many of whom were young women by engaging an unwanted groping kisses hugging and by making inappropriate comments governor. Cuomo said his instinct was to fight but at the start of the week his top aide told him she would resign an assembly speaker. Carl hasty gave cuomo no way out of possible. Impeachment i am not negotiating in deals

Andrew Cuomo Aaron Katersky Cuomo Abc News Charles Levin Frank Charlotte Bennett General Latisha James Judiciary Committee New York Governor Cuomo Carl Hasty Assembly
New York Assembly to Suspend Cuomo Impeachment Investigation

AP News Radio

00:38 sec | 2 months ago

New York Assembly to Suspend Cuomo Impeachment Investigation

"The New York State Assembly will suspend its impeachment investigation into governor Andrew Cuomo once he steps down speaker Carl Heastie said in a statement that the assembly Judiciary Committee had heard from its lawyers that it can impeach and remove an elected official no longer in office Andrew Cuomo who wanted a fourteen day transition period announced his resignation this past Tuesday over sexual harassment allegations which he has denied some members of the Judiciary Committee said they wanted the group to at least release a report of their findings to the public it wasn't immediately known if that will happen I'm surely after

Andrew Cuomo Carl Heastie Assembly Judiciary Committee New York State Assembly Judiciary Committee
California Sheriff: He, Not Doctor, Diagnosed Video Overdose

The DeMaio Report with Carl DeMaio and Lou Penrose

00:35 sec | 2 months ago

California Sheriff: He, Not Doctor, Diagnosed Video Overdose

"County Sheriff Bill Gore is acknowledged that he not a doctor concluded a deputy overdosed from fentanyl exposure while searching a vehicle for drugs. Body worn camera footage released last week shows the deputy following falling to the ground and struggling to breathe after coming within about six inches of the drug. The union Tribune quotes the sheriff is saying it was classic signs of fentanyl overdose. That's why we called it that. Health experts told the newspaper. Fentanyl is extremely dangerous, but inhaling a small amount doesn't lead to an overdose and say they suspect the deputy essentially passed out due to fear.

County Sheriff Bill Gore The Union Tribune
Ex-LAPD Officer Charged With Manslaughter in Connection With Deadly Costco Shooting

The DeMaio Report with Carl DeMaio and Lou Penrose

00:40 sec | 2 months ago

Ex-LAPD Officer Charged With Manslaughter in Connection With Deadly Costco Shooting

"Facing manslaughter charges for the deadly shooting of a developmentally disabled man and the wounding of his parents at a Costco in Corona while the officer was off duty two years ago, former officer Salvador Sanchez was arrested this morning and is facing felony charges of voluntary manslaughter and assault with a semi automatic firearm for the shooting. 32 year old Kenneth French was killed. Sanchez lawyers said he was holding his son and knocked to the floor, fearing for the safety of his son fired his weapon. Riverside County prosecutors have decided not to charge Sanchez and Sanchez lawyer says the charges are politically motivated by the state attorney general in Chicago this weekend.

Salvador Sanchez Kenneth French Costco Corona Sanchez Riverside County Chicago
"carl i" Discussed on Citation Needed

Citation Needed

08:36 min | 4 months ago

"carl i" Discussed on Citation Needed

"Think. I don't know tom's gonna explain. Let's say. Hey carl greetings steven. Yeah so the guys now. We're going to go out for a few beers after work. You wanna come along alcohol. Where does the senses. Why would i wanna feel this world less than i can. I don't know it's it's taco tuesday. I care not for the taco. it is man's attempt to hide his kills beneath the taco. Shell of his own fear when your life you should know it. Stephen you should celebrate it. You are become a gall fun. Yeah totally totally. Hey speaking of you talking like that. We got a chance to look over your proposal for you going to a different continent and not being on this one and approved. It was approved unanimously. So go ahead and do that. Everyone would like you to do that. Excellent i she'll freeze the world's most exotic life and tie for all of the sounds good and just one of the thing. There's cake in the break room for carol's birthday if you want them Cake the sweet replacement for life this show so no you would not cake. No i'll have cake okay. Cool it's it's back there. Is there a quarter piece is not quarterbacks. And we're back when we left off. Jeffrey dahmer was really taken to his job at the canon. He's okay i anyway. i do. I expedition africa. Carl's in somaliland hunting for warthog and hyena and he got one of each earlier in the day. However would carl went to look for and retrieve the dead animals. They were not worried seeing them. Go down and said there were two long blood streaks leading off into the bush carl realized something had grabbed his kills and it hauled him off to eat them and justice. He had this moment of clarity. He heard a noise coming from the bush. Carl fired a shot into the air to frighten away. Whatever just drag off a big ass wart hog corpse rather than scare the predator in it an eighty pound leopard bursts from the undergrowth and leapt carl. Carl dropped his rifle was able to raise his arm in time to protect his throat but his hand was now firmly locked in the jaws. Leopard which is also attempting to eviscerate. Carl with its back ause. Carl struggled to free his hand but every time he pulled away. The leopard bit down harder. So carl stop trying to pull his hand out and he began to punch the leopard at its own. Goddamn throat from an leopard. Lego carl picked up the eighty pound flailing screeching hell beasts slammed it against the ground then leapt upon it and choked to pictures or get the fuck out. None of that is almost word for word. The same story. I've heard from like twenty drunk irish got at the end of my bar. I'm sam store. If you africa for denny's parking lot leopard for an ethnic slur leper was daddy pulled off the mask and it was ramos stereo senior down there all right all right fine if fighting a leopard to death. Isn't it clearly. it's not yes. He did this while he was also recovering from malaria and the hand that he used to throat punch. The leopard was absolutely shattered and he was bleeding. Like a son of a bitch from all of them has more gallons and lobo muffin pill to get back to school. Naturally that he picked up the dead leopard walked back to camp. Bill and that fucking thing as taxidermied and has become a museum exhibit on another occasion. Car was on expedition in kenya. One of his orders alert him that the big elephant reporter had ever seen was around. So i decided track this elephant for a while and they can kill it so when all the other elephants are dead. We can look at one of them that we killed and say hey that was. It'd probably should've killed all those now. Anyway these guys are tracking this elephant. They think they've lost track of it. When all of a sudden explodes interview and it charges. Carl is able to get out of the way quickly enough and the elephant wax him in the face with its giant elephant knows peanuts. That's amazing that they use the they use the nose to like whip. You arsenal punched awesome clothesline. A burst open. Carl's face broke his nose and through the ground. Carl stood back up just in time to see the elephant charging again down and tusks forward. So carl cut jukes bit. Grabs one of the last slips is body between them to avoid getting reviewer. the elephants unable to just shishkabob. Carl then mashed. It's enormous head into the ground with carl pinned potential grooming so hard for this elephant image immediately carl's lung was punctured by one of the six ribs that broke upon impact the elephant then got up and chase a few other guys around for a bit and then ran off triumphantly. Not that i just love. that coral thinks he quote. Duked it right like this elephant charged in being lack riposte remain my fencing moves basic slam now flash the elephant walking away. That was for you. I'm an run stiff arm so the elephant ran away. Carl are wasn't looking so well he wasn't looking so bad. That is local. Native guys thought he was dead fish. Start stopping him. What he would of water in local customs in the area forbid the locals from touching a corpse so they lit a fire nearby and they just went away. Mary ways unaware that he's dead. Everywhere littered with dead people. No matter what so he gets us that we get a new house. Makes the experience of visiting people's grave. A lot to kara wasn't dead though he was severely and gravely wounded. Carl lay on his back for five hours in the rain. Alone with a punctured lung and six broken ribs until he regained consciousness and dragged himself back to camp. His wife nursed him to health for three months before he was able to walk. Elephant comeback. six hours later. The bagasse straw under one arm and a carve sign. That says thought he could juke me. He's looking around. Fuck this t shirt for nothing. That's that's your leopard took it. Mother acme elephant gun on a trip to uganda. Carl was hunting crocodiles and he shot a huge nearby a river. So carlin is order. Start sweating across the earth to retrieve the dead beast with a border was attacked. Killed any eaten by a crocodile just yards from where carl was himself swimming. The carl made it across. Japan was alone and across a river full of hungry dinosaurs. That didn't get their memo sixty five years. So carl did the only thing i can think of. He pushed the crocodile that he just shot into. The river climbed aboard its korb's and pedaled a dead crocodile across the river full of very much alive crocodiles to get himself to the..

Stephen kenya uganda carol Jeffrey dahmer steven eighty pound five hours Japan tuesday somaliland Mary sixty five years Carl six broken ribs one arm one carlin africa Lego
"carl i" Discussed on Citation Needed

Citation Needed

07:15 min | 4 months ago

"carl i" Discussed on Citation Needed

"Obviously the field. Not yet in. Its prime and carl was convinced that he could do better than he could create pieces that were vastly more realistic and lifelike. And that would better represent the truth and beauty of the beasts of the wild so carl took an apprenticeship with the only taxidermist round wasn't just over stuffing bloated animal skins to bursting. Vegas is the guy named henry any operator. Ward's natural science establishment and reward struck a hard bargain with carl and for the some of three dollars and fifty cents a week. Carl agreed to work every single day sunday through monday with no vacations and no holidays and no meal breaks slow from seven. Am to six pm. But in exchange she was free to practice his own methods just as soon as he had completed his eleven hour shift. Somehow carl found the time to work on his own methods for taxes. There are a hundred and sixty hours a week tom. He's only working seventy seven of them. Okay so people just don't want to work anymore is what it is hand out. Gotta get rid of that. Eighteen hundreds unemployment right. What are the first things. Carl notices that fairly quickly actual bodies were not in fact just like skin tubes. Build undifferentiated sneak for yourself again. Ted cruz is recalled. In the moment it's a desire lifelike effect was not going to be achieved by simply piling a bunch of rats with dr animals it turns out were in fact full of bony skeletal stragglers and muscles and be like carl said about creating a framework matched the build and composition of the original animal sometimes using the original animals own bones as that framework he then used plaster and modeling clay sculpting interior of the animal that he was working with that the musculature and shape of the creature was realistic before carefully laying the preserves skin and hide over the framework masterfully. Hiding any seems he was thorough and he was meticulous and honestly his results were extraordinarily. Okay so. I want to downplay the importance of carl's innovations here but he revolutionized the industry by realizing that animals had no missing must've been so much easier. Do one guy to another guy. Animals used to be crunchier today now. He was of course fired. Yeah now for his work but for falling asleep on the job from exhaustion a carl felt hurt and betrayed it having been fired and he left rochester to work for commercial taxidermist in new york city. This job was worse than last though is the owner was described as irascible and dominating and the work was uninteresting and unfulfilling leaving car with no room to expand on his craft thankfully henry ward quickly realized he had fucked up and firing carl and wrote him a letter apologizing and asking him to come back to rochester which carl did in eighteen eighty four hundred. Just read sorry. Carl you're right. They are filled with bones. There's no garbage in their reward entirely bonds or to a. Where's karl point. That things began to get interest. You promise off shots fire. Cpt barnum's elephant jumbo adjust died and he needed to be taxidermied for reasons. They don't say way. Barnum turned award and ward carl the process of preserving the massive beast. Carl way took five months to complete a because they didn't have enough garbage legroom stomach but the result was a presentation far. More life. liked taxidermy to ever before produced that elephant was in some ways a big break and two years later. Carl aac lee was working at the field museum of natural history in chicago. He's stuck inside the elephant. He's trying to fold of fitted sheet these. I'm the finally just wanted up at sticking in the fucking time again for a quick moment of digression how many digression steeper with exactly right. Remember this into a tub of cold water back remember. This was the late eighteen. Hundreds and america and the world hadn't figured out a god damn thing about how the world worked yet but we had figured how go yes and anyone at this point who felt like doing so could just travel on a big game trip to africa and kill the ever loving shit out of whatever caught their eye the idea of conservation while not strictly a new idea was not widely accepted an enormous populations of massive game animals in africa. Were being slaughtered just for the funsies of it. There was a real concern. That many of the large game species that would be hunted would be hunted right into extinction leaving no trace of having ever existed those who curated natural history museums felt the need to preserve the legacy of the natural world not just to document it but to literally physically conserve evidence that these animals were in fact real so when i tell you the next part of the story keep in mind. The hunting and stuffing of animals was thought of at the time as a legitimate scientific documentary record after some time at the field museum. Carl took a job at the american museum of natural history in new york for zero dollars. That was his. Sal could work yeah. He's only stipulation on. His work was at the museum finances. Expeditions to africa that he could hunt kill and ultimately preserve a number of species he found fascinating across the continent. His goals to be basically a kind of reverse new does this to people in georgia. He goes out matter no lucians. It was very confused. As the original noah on this recording the namesake. Okay so the idea would kill between two and five of every big animal he could find and then take them back to his weird build. A bear franken preserve their corpses. So we could all feel a little guilty looking at them. One hundred and forty years later so comme sure. They survived the future. He killed them. Yes house mary american. All right well red flags. The guy is about to go on his first killing animals. So it's good. I.

Carl aac lee africa georgia chicago Carl five months new york Ted cruz six pm zero dollars two seventy seven carl monday three dollars eleven hour karl five today new york city
"carl i" Discussed on Citation Needed

Citation Needed

08:02 min | 4 months ago

"carl i" Discussed on Citation Needed

"Everywhere seasonal and no. It's the ancient remedy for the opposite of male enhancement to know that explains all the things i've been seeing under boxes and also joining us tonight. Two men who assure you they each want their own rhinoceros heath and what is for the table even here with i'ma three that's why dine alone it avoids any of that awkward confusion. That's what i'd tell you so lonely. Just missing he. thomas sees. It's ooh april year before we begin tonight. I'd like to take a moment to thank our patrons and if you'd like to learn how to join their ranks be sure to stick around until the end of the show and win that out of the way tell us know what person place thing concept phenomenon or event. Will we be talking about today today. We're gonna be talking about karl and tom. You're obviously trying to get on. Karl's good sites that you're not as next victim follow this trail wherever it goes all. Eli have lived my whole life just trying to feel stuff. So let's do it so tell us tom. Who was carl kelly. All right guys. I've been wanting to tell this story for a long time. But it's a timing just wasn't right until now because this is a story of a guy so unbelievably bad as we just like rush right into it without being properly prepared. We'd almost certainly tear something. I'm going to tell you a story today about a guy whose name you almost certainly didn't already know but whose work you may have seen. And his influences you have certainly felt and his occupation and craft is absolutely buggy whip outdated. This is a man who lived enough life for you me and everyone else you've ever met. This is a story of carl ache. Like i feel like you're avoiding. Alleged question on was just asked to name his favorite supreme court battle question. You see and then we'll start there. Five formed an ad hoc committee to decide spending more time with my family in lieu of recent about okay or on a farm in clarendon new york in eighteen sixty four. Carl was even at a very young age much more interested than most animals. Now you might be thinking. I don't know tom. I really like animals and yeah ok you probably do. Carl spent his time in the woods. Teaching himself to paint incredibly realistic renderings of them with absolutely no training still not impressed. Okay well he was poor and his family didn't have any proper paints so carl improvised and taught himself to paint without direction on how to paint and also using his own blood as meet his own. Hey carl just so many other read things. There's so many things that are. I feel like you shut down that brainstorm real quick heath. It is than watercolor ally is obviously blood. Porteous of chipmunks weren't just going to cut it forever we we all have to learn that last top one. It's a tough one. Carl was just really fascinated with nature and animals at the age of twelve discovered. What would end up being the first step toward his life's work. When his cousins pet canary died he saw that she was distraught and asked if he might be allowed to stuff the bird for her to quote. Fix it you see. Carl had seen the work of taxidermist. David bruce at a free exhibit in rochester not long before and he was mesmerized by the idea of the whole thing so we took his cousins canary skimmed. It stuffed it so couple of glass beads for ships and presented. This nightmarish craft project tour presumably. So that her fear and revulsion clip. Terrible i abby your cousin who paints his own blood took it upon himself to create sort of an hp lovecraft freeze oppose liver. And say thank you. So that we're not as i victims garlands or next. Six years learning could about taxidermy before moving to rochester to pursue his passion. It is at this point though. I feel like. I do need to pause and needs. Explain to you. What was meant by taxidermy in the late eighteen hundreds before carl egli came along. Taxidermy was at this point to put it very gently a crude affair. Yeah it's not the classy art attacks by comparison eline taxidermist would typically take the animal. They were working with it. would skin it. They would treat the skin. It mostly didn't rot entirely. Then they would stuff the skin with and here. I am not exaggerating at all. Just whatever crap they had lions for real so many page you a picture. Imagine for yourself a lion which has been shot killed and skin that skin now treated as just a formulas. It's not really lion-shaped in any way the taxidermist just start stuffing. The empty skin like cramming a pillow into a lion chan awkward. And would they stuff. This lion skin with will straw sometimes if they had it or cotton or actual bitch that they had just laying around. They weren't spending money on this season. Whatever was about so instead of at the end instead of a lion. You basically had a weird distorted overstuffed novelty sideshow lion-shaped thing that mostly didn't rock. Carl referred to this as the upholstery method of taxidermy. stuff garbage in their couches. I know we're laughing but this this method is still in use today. That's literally how ted cruz keeps shape. Ask it is a garbage. Someone's holding ted cruz under their skin. And things. Resisting are gentlemen. I can't just leave it there. And i know this is not a visual medium but i would be depriving you. If i didn't share with you a photo of taxidermy which was in a fucking museum in eighteen thirty eight this picture gentlemen take. Okay this was newseum plug in eighteen thirty. We're looking at a lion. Are we supposed to be a lion. It's just take a bite of an antelope or something like that and shape of the lion. Yeah it's great. It's not it's not great highs are the women who like this lines. Mom very clearly just walked in from the other room being like honey. Just make sure you don't eat the live antelope with irby's in the fridge. We started all my cut. It is to lion as like when you're nearsighted grandma but beenish ban. Sorry you said this was in a museum folks if this is museum quality. We just don't do this. This is like starting a space program when you just have catapulted time. I wanna pipe in here as a medieval recreation est. I think thing it looks fine until.

carl kelly tom today karl Eli Carl Six years tonight rochester carl egli carl ache Two men Karl David bruce clarendon new york Five each first step thomas three
"carl i" Discussed on Citation Needed

Citation Needed

01:35 min | 4 months ago

"carl i" Discussed on Citation Needed

"And when it turned out she'd been a horse the whole shell. I know it was a it was right there in the title the whole time so good look to the left. My left or comes my my left. I'm yours yeah monday monday guy okay guys. I'll bite this time. What why Yes no see so. Welcome to the hall of podcasting. Thought we hadn't settled on hall of podcasting. I didn't we didn't put a pin in the tidal conversation. Tom eagle using a heath. Tom and i were thinking about this. Week's episode. carl egli. Yeah he worked so hard to preserve what he cared about. You know and we got to thinking about podcasts. Okay but they're on. The internet. People can just narrow no not that part of podcasting. No like the lived hearts. Nobody gets to see this. Is this like buying a microphone that you'll never use yay use it. I might use it. My backups could fail backups. Backup field for this exhibit going over the just time even though you know the episode is done. Oh okay so that's an important one. I get that people down of course a core of the exhibit explaining to your parents. What a podcast is. Yeah that's a good one right. really captured. The disappointment in the dads is there.

Tom carl egli Tom eagle monday
"carl i" Discussed on First Rounders

First Rounders

03:22 min | 5 months ago

"carl i" Discussed on First Rounders

"Of war. I mean <Speech_Male> <Speech_Male> <SpeakerChange> <Speech_Male> You know. I really <Speech_Male> love patient contact <Speech_Male> and <Speech_Male> my i have a son <Speech_Male> wants. A phd <Silence> in was an md <Speech_Male> and <Speech_Male> one sees patients. Full-time <Speech_Male> one sees <Speech_Male> labs fulltime. <Speech_Male> And i <Speech_Male> had to end up making <Speech_Male> a choice because <Speech_Male> as like <Speech_Male> sports and stuff <Speech_Male> Things become more <Speech_Male> specialized <Speech_Male> and then my own experience <Speech_Male> with my wife. <Speech_Male> I basically <Speech_Male> i spent five <Speech_Male> years taking care of her. <Speech_Male> And then i never went back <Silence> to seen patience <Speech_Male> <Speech_Male> after that. <Speech_Male> I've concentrated <Speech_Male> on the basic <Speech_Male> and translational <SpeakerChange> research. <Speech_Male> So but <Speech_Male> <Speech_Male> you mean. <Speech_Male> <Speech_Male> I wrote the <Speech_Male> isd <Speech_Male> said investigational <Speech_Male> new drug. <Speech_Male> That i got to get <Speech_Male> what became <Speech_Male> mind <SpeakerChange> was seven <Silence> hundred pages long <Silence> <Speech_Male> while no <Speech_Male> you. Don't get any <Speech_Male> grants or papers <Speech_Male> out of that. <Speech_Male> Yeah you have to <Speech_Male> dedicate a whole <Speech_Male> lot of time <Speech_Male> and so as a tenure <Silence> professor. I could do that. <Speech_Male> But <Speech_Male> there's a lot of people <Speech_Male> who are qualified to <Speech_Male> see leukemia. patients <Silence> here at penn. <Speech_Male> But i <Speech_Male> had the kind of unique experience <Speech_Male> to write. <Silence> You know how do you take <Speech_Male> <SpeakerChange> a t. <Speech_Male> cell culture thing <Speech_Male> and then make it into <Silence> a drug <Speech_Male> so i'm <Speech_Male> more value. <Speech_Male> You know if <Speech_Male> you look at value added <Speech_Male> on much better riding <Speech_Male> <Speech_Male> and getting <Speech_Male> new bench experiments <Speech_Male> in the translational <Speech_Male> trials <SpeakerChange> and i <Speech_Male> am seeing patients <Speech_Male> yet <Speech_Male> makes sense <Speech_Male> one of one versus <Speech_Male> is you know <Speech_Male> read maybe <Speech_Male> thousand benefits <Speech_Male> by you know <Speech_Male> if they have <SpeakerChange> a trial that's <Speech_Male> works at <Speech_Male> all. Yeah <Speech_Male> <Speech_Male> thank you <Silence> really enjoyed this <Speech_Male> <Speech_Male> through a fun talking to you <Speech_Male> brittany. Hold on one second <Music> hold on. <Music> <Music> <Music> <Music> <SpeakerChange> <Speech_Music_Male> <Speech_Male> That is your <Speech_Male> first rounders. Podcast <Silence> with carl. June <Speech_Male> as <Speech_Male> usual fully <Speech_Male> enjoyed myself. I <Speech_Male> learned a lot. <Speech_Male> Thanks carl for <Silence> participating. In this. <Speech_Male> I <Speech_Male> would like to point out <Speech_Male> that we have a sister. Podcast <Speech_Male> called forum. <Speech_Male> You can find <Speech_Male> by searching form <Speech_Male> in each biotechnology <Speech_Male> wherever you get your podcast. <Speech_Male> We just released <Speech_Male> a new episode <Speech_Male> roundtable <Silence> optogenetics. <Speech_Male> <Silence> If you have comments <Speech_Male> on that <Speech_Male> podcast this podcasts <Speech_Male> or anything that are journal. <Speech_Male> Does you can find us <Speech_Male> on. Twitter <Speech_Male> or handle is at <Silence> nature biotech. <Speech_Male> A measure <Speech_Male> of thanks to the mid west quite <Speech_Male> for use <SpeakerChange> of your music <Silence> in i would say i'd <Speech_Male> like to say <Speech_Male> that the positivity <Speech_Male> rate uncovered <Speech_Male> nineteen tests in <Speech_Male> new york city over <Speech_Male> the last fourteen days. The average <Speech_Male> two percent <Speech_Male> two percent <Speech_Male> positivity rate <Speech_Male> the vaccines <Speech_Male> work. thank you madonna. <Speech_Male> Thank you pfizer. <Speech_Male> Jj astrazeneca <Speech_Male> everyone working on <Silence> covid nineteen vaccines. <Speech_Male> The <Speech_Male> city is. <Speech_Male> At least it feels like <Speech_Male> it's healing and a lotta shuttered <Speech_Male> restaurants. A lot of storefronts <Speech_Male> boarded up. <Speech_Male> But at least feels <Speech_Male> like we are on <Silence> the <SpeakerChange> way back. <Speech_Male> <Silence> Thank you for listening. <Speech_Male> <Speech_Male> I'll talk <SpeakerChange> to you on the next <Speech_Male> one <Music> and goodbye <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Music> <Advertisement> <Music> <Advertisement> your <Music> <Advertisement> own.

two percent five new york nineteen vaccines Twitter hundred pages nineteen tests Jj astrazeneca June one second first rounders Speech_Male seven brittany each pfizer leukemia one years last
"carl i" Discussed on First Rounders

First Rounders

03:03 min | 5 months ago

"carl i" Discussed on First Rounders

"Payloads into the brain from the peripheral blood. Antibodies traditionally have a really tough time. Do yep so inflammation. I had a paper with john epstein about a year ago in nature targeting fibrosis in the heart and there we targeted fiberglass activation protein and the paper nature showed we could prevent congestive heart failure in mice and it turns out in various forms of heart failure and adults. You if you treat the fibrosis the heart repairs itself in where our mouse model show and so there may be well big opportunities targeted information in the brain and l. r. p. Three for instance. And it's huge malacca complex. And i think we can get reagents there and whether that will repair alzheimer's or prevented you know all those things need to be tested. Having novel ways to target inflammation. I think is really important. Those for for dementia. I mean alzheimer's is like we're always looking for new ways to tackle that nothing seems to be have really pegged at yet no and so what we do know is inflammation has a big role and how we get and then once you have targets than you got to be able to drug them yet and I think So i'm really interested in working with a c. Immune on taken and they have really good targets within an l. p. three in particular and some and i think i may have roles than. In the periphery for cancer. You know there was really huge. Finding an artist had a few years ago with al one and tag them and they did a trial to see blocking. I'll one and the systemic inflammation would in people with bad heart disease would it prevent progression of atherosclerosis and heart attacks. Fix would they found was there was a huge anticancer effect. The trial was large enough that this was an annoying journal. That blocking inflammation decreased the diagnosis of cancer. Many of the patients have been smokers stuff off. Kansas of all kinds. Yes well lung. Cancer was was the main important trial so that was a mean. Novartis has targeted nile. One and it was. You know it was powered enough. That was a subgroup analysis yet. So so there's gonna be. You know their liquid biopsy techniques and all that diagnosing cancer early preventing and treating inflammation will be have anti cancer effects as well as i think. Anti Affects on dementias when when I think maybe this is the last thing. I'm gonna ask you but when you when you were seeing patients did you enjoy it. The way that you enjoy you did. Yeah so it was a big.

john epstein Kansas few years ago One about a year ago Three atherosclerosis Novartis
"carl i" Discussed on First Rounders

First Rounders

03:29 min | 5 months ago

"carl i" Discussed on First Rounders

"Is i mean he thought he was going to die as i mentioned papers funeral. And then so he gets. He bought an rv and he and his wife toured the country all kinds of photos. We got gone to the grand canyon. Things like that. I mean he lived a normal life. Yep and then. Then got snuffed out right. I was thinking about this. Because of the terrible response that he had that he was literally his body melting the cancer way but if he had died that would have been a jesse gelsinger and that was shut down. Incomplete correct. i mean did you get. Is you get one chance to hit a home. Run on air. I trump patient if you have if you have a lethal adverse event. You are shutdown. I mean there is no place to hide that. That's that's it. you're exactly right. So if he had died Our protocol would have been closed end up and that would that would have stopped work in this field for who knows how long no until right and So we were extraordinarily fortunate to and then similarly know so. That was two thousand and ten. We treat amply whitehead our first pediatric patient in april. Two thousand twelve and she almost died. She you know with the pediatric have actually more severe s decided storm. Yep i mean their immune system is better and We didn't we does not a scaling between body. Wade's interns turns out. You need less sells for kid. We didn't know that. And we treated her and she had a really potent response and and almost died and if that happened know would have been game over. Same thing right for pediatric. But but there we had. I was serendipity played a major aspect in her life So we were major insider kinds in real time and she you know we treat it on tuesday on friday. She was transferred to the icu. With multi. organ failure was Kidney failure was comatose. Oh my god placed on a ventilator. And can i let me ask you because you've seen this with bill did you think. Did you think plus you might come out of it or did you think. I mean the organ failure. You have to think that's gonna you know. I mean so. She was sicker than bill and pediatric. Patients are or more resilient. But i mean our pediatric physician. Steve grow up. Said he'd never seen a patient that sick and cover and but My daughter who was at harvard then undergraduate has juvenile rheumatoid arthritis. And you know. I mentioned my mom has lupus. I have to our immune diseases and So as a result. I follow what experimental therapies are out there for you know autoimmune diseases and i knew about a drug that only three months before benn. Fda approved arthritis. It's called in our totalism at that roche. Mix and it blocks. I'll six receptor signaling. Yes and we masur decided kinds and publish them in emily. I knew about him in real time. Horizons six went up a thousand thousandfold about baseline and so that was act. Aside said i called. And i was actually giving a talk and seattle and got the lab results back from my lab and.

Steve april Two thousand jesse gelsinger tuesday on two thousand Wade grand canyon Horizons six one chance bill ten friday harvard first pediatric patient benn. Fda three months emily twelve
"carl i" Discussed on First Rounders

First Rounders

05:57 min | 5 months ago

"carl i" Discussed on First Rounders

"As soon as i got the pen. I see okay. Then you had your freedom to sort of investigate. I wanted to exactly. Yeah okay and then so you somehow okay. Well we've got these cd. Nineteen is a target for b. cells. Can we can we reprogram these t. cells to attack that yeah began. I was initially Studying using cd. Twenty of yeah and But it's dan. Rebel was working on that with all the press. One of my fellows. When i was training at the hutch in seattle and manure branches mills. Michelle satellite know working with their gamma retroviruses memorial. Sloan kettering and they they decided. Cd nineteen if you look at the expression see nineteen was probably better target than see twenty. So that's what we all and in conjunction with fda's target with the first car t. Cells was see nineteen. The drug industry had ignored it. While because genetech atas big success with saab you know targeted cd twani initially and so they just stayed with that because of inertia but see nineteen is actually a better tarp. Okay it's brighter more copies per cell and it's expressed earlier in the lineage of these cells than cd twenty. But did you know knowing that genetic. It's sort of pave the way with a cd. Twenty did you have to convince people that this other target might be worth pursuing where we so ali The group actually did trials and with mike jackson. Who is dan down at city of hope. They actually did trials with retirement. See twenty base cars and on the east coast michelle satellite and and and my group a pin so memorial and penn we targeted see nineteen okay and fda had no real problem because we could in preclinical models. Show that leukemia cells. Express that and there's a lot of genetic data that cd nineteen lineage marker. That was only on the only thought to be on the cells and And but you know we just had a paper and sell this last year..

mike jackson Twenty last year first car Nineteen One east coast Michelle twenty twenty base cars seattle nineteen lineage nineteen Rebel Cd michelle
"carl i" Discussed on First Rounders

First Rounders

04:09 min | 5 months ago

"carl i" Discussed on First Rounders

"You know what are you working on. How your grad students. Yeah so it was. I had i was only one of the navy to have an ro one grant so back. I had had data on how to grow cells. Yeah and that was a couple of papers in science and we found out that. Cd twenty eight was a very potent growth factor. Yet and so. I've been studying. These co stimulatory. Nice and four of my senior lab people move from bethesda here a pen okay. That's got started. Yeah yeah. And then i started getting 'cause my lab before but as been had post docs so now i started having both graduate students and post docs and in things really took off. I mean i had one of my first graduate students in. mvp students. Here at penn was marcella. Mouse elkins now associate professor harvard yet. You know doing cartesian therapies. But her project was studying foreign bb on t. cells and we found out that it was a really potent growth factor. You know in addition to see twenty eight so we studied one amalgamates traff signaling pathways and the other allies and fat and so on so we found out how these pathways were different and with a shared and then use those as card designs right. This is the first step sort of like okay. Yeah i need to grow t cells. How can we do it. We can't if we take it from the patient we can grow them them back. That was the first step right. Yeah and when. I was in the navy. Bruce levine came my lap from hopkins. Phd ins in biology. And i had him start using. Because i don't see two thousand eight Antibodies may t-cells grow so then we found out it had. This is the truth of this experiment. Which the two papers. In science we started studying hiv up. And what cd. Twenty eight did there and we found. We could grow t cells from patients with hiv and the virus never came out. We when you normally grow t cells from hiv infected patients. A whole bunch of ours comes out and then kills a cd four cells while leaf and and so we normally would grow up you know. Hiv infected volunteers to take their cd. Four cells outgrow them and then use that to make viral stocks of hiv pathogenic virus to use experiments. So bruce door my lab and we had used cd twenty eight conjugated on the beads. As a way to conveniently activate cells and the t. cells. Were gross at bruce when she go make your own stock of hiv so he got a couple of donors who had hiv aids and grew their t. cells and then three days later. When when they're dividing light you harvest the supernet and spin it down and that now you have a viral stock in you. Measure p twenty four. Well he did that. And there is no virus and i literally got angry at him. So how can you can you screw that experiment off you know and so i went down and did it myself. Then yeah and no buyers get and so what we found out and this was in science was cd. Twenty eight in in like that actually transcriptionist shuts off the course after cr five okay and activate and if you use the other molecules see till a four which is related to see twenty that turns it on and makes a cell sitting duck for hiv. So there's this yang-yang t cells can be made resistant..

bethesda Bruce levine twenty eight Twenty eight one two papers first step Four cells two thousand eight Antibodies three days later four four cells Mouse elkins harvard both graduate first graduate students four of my senior lab cr five eight donors
"carl i" Discussed on First Rounders

First Rounders

03:40 min | 5 months ago

"carl i" Discussed on First Rounders

"And so i had. I applied and got accepted to caltech into stanford berkeley from where i live and then i got a draft number that is vietnam war graduate high school. Seventy one seventy one okay. Yeah so i ended up going into the navy. Where for two stale rice. I went to the navy naval academy. And we're on the east coast and in the war got over and seventy four real graduated and the navy started a pre med program. And i had done things that have you know biology experiments just at a natural curiosity instead in high school. But i know one of my family ever been a position. So i had no clue. I decided 'cause i went into the navy thinking i've ever going nuclear power program for our viewers out. 'cause i had a five year obligation paybacks in the naval academy and then it turned out. I mean they paid for medical school. Sr got interested in that may people out of my class the rest of them went on the submarines and serious latte style. Okay i was the naval academy your fulltime obligation the navy then for five years to pay back the got a bachelor science chemistry. Yeah so then. I ended up saying well. This sounds pretty cool. The medical Wasn't even their brochures and stuff like that that they had a pre med. And then i could get into medical so so i went straight to medical school from college. And then you know it's been adjourned at end in. Initially i couldn't do research got trained in in leukemia. all because a navy had reactors and they're worried about limited radiation exposures. And so i beaumont transplantation in the fred hutchinson before you realize that draft going to be a problem. Did you think that you want be a physician. Then or no you. You're thinking oh our and but they never had backed in these kind of things of what are your real interested in you know and and i you know obviously the cap goes club and all that and i like math and science but but i did have i just never thought of maybe i should go be a physician because no one done that met family but i had a couple of experience in high school and under you know where physicians really helped me like. I broke my arm badly a couple times and a couple of got in a fight in fifth grade. An arm was was bent. I mean i literally had to have it set by an orthopedic surgeon alma. God i remember what that was like. And then i you know but and i had done. Experiments actually bought mice rats and dissect them i'm my i got trichloroethylene for my mother's cleaning fluid and use that as nanas and did lot survival surgery on rats when i was in seventh or eighth grade. Just because i've i've interested in. But i didn't think i'd be a anything. Do the research but an these. Its first off this fighting. Fifth grade sounds terribly vicious for breaking an arm of you know what happened. Actually so this guy had ripped my jacket and we had kind of ongoing thing going and then what happened was i started chasing him and i caught him but then he went out and i flipped over him and there was a whole and i fell into the whole and that bridged across broke my all my god. This is what happened. I mean that was fifth grade And i broke it twice. I mean three months at a cast. He said he can't do anything where it in a sling for like six weeks. The very next day at broke my arm again plant soccer..

six weeks three months navy naval academy five years five year fred hutchinson seventh naval academy twice caltech first fifth grade Fifth fifth stanford berkeley eighth grade next day vietnam war two stale rice leukemia
"carl i" Discussed on First Rounders

First Rounders

03:54 min | 5 months ago

"carl i" Discussed on First Rounders

"Welcome to nature biotechnologies. First rounders podcast. My name is brady hugged. I'm the host of this show since two thousand and thirteen the host. This show. isn't that crazy. We've been doing this That long the guest today. it's big guest. Well they're big guests but carl june. And why is he a big. Because he's a pioneer encarta cell therapy. He's also a co founder of team unity therapeutics and he runs june lab out of the university of pennsylvania We talked about how the vietnam war disrupted. His college plans sent him into the navy. We talked about How the death of his wife actually caused him to look more closely at translational research. This is the second straight guest that has talked about navigating the oceans by the stars. Just by chance craig. Mello talked about that too in episode before this carl talked about if you're doing work that outside the box as he said it's going to be hard to find funding and we talked about Saving emily whitehead's life what that meant to him and her obviously. That's that's in this podcast to. I don't know there's anything else you need to know. i'll have some housekeeping things at the end but for now here. It is your first rounders podcast with carl june. Listen up. oh you're in the office the items that are come in a couple of days two days week bread now. I.

Mello carl two days two thousand today First vietnam war rounders carl june june lab second straight guest first rounders brady hugged pennsylvania emily june thirteen whitehead
"carl i" Discussed on Bloomberg Radio New York

Bloomberg Radio New York

04:38 min | 9 months ago

"carl i" Discussed on Bloomberg Radio New York

"Carl, you know, he talked about a lot of things that we often talk about. Or he often talks about the Fed chief. What stood out for you specifically. Good afternoon, Carol Loud. What Sit up for me was the consistency with prior messaging, which again? No news can be news in the context that we have seen more economic data. We've seen that GDP. We've seen a few more jobs reports. And so what? Even though he echoed a lot of themes that he expressed that the Jackson Hole conference last year and the insulated Fed meeting the fact that he still is standing resolute, even though we've seen this rising market yields and some concerns out there about inflation pressures mounting that Jay Powell is that not swerving in the least he is entirely focused on this huge Deficit of jobs that has to be filled before we can even consider whether the economy has normalized post covert. Okay, So Carl, what is his message to those people who are so concerned with rising inflation? Well, The message is that there is not rising inflation in the economy and this is something we emphasized that this morning in a note as well as that was corroborated with the latest consumer price, said data. We can see that consumer prices are decelerating. The trend is even more pronounced in the service sector, which is tied into the labor market to have greater deal in good thing. Good prices. For instance, there simply is not inflation and the economy and that should come as little surprise. When we think about it if macro economists because inflation is a lagging indicator of activity in activity has been pretty lousy over the course of the last step four quarters and so that tells you that we're not generating much inflation in the economy. And for that reason, I think a lot of these concerns about whether stimulus three point no. The latest Biden proposal is going to cost the economy to overheat. I don't think that's the case at all. It may shave some of the trough off of inflation this year, but this is not pushing us into some sort of wage price spiral by any stretch of the imagination, and I just felt that everybody know I feel like there's been a little bit of firming in the equity market. Doesn't peace now up about eight points douse up 124 points in the NASDAQ's better by about 14 15 points. If I look at the Treasury market, which can often be sensitive, obviously to what the Fed says, and certainly what Jay Powell says the 10 year note with yield of 1 13 5 Year note building 50.45 that two year notes with the yield of 20.11 you know, it's interesting, Karl. So you guys have been putting out there about not being worried about Inflation. Jay Powell once again being very firm, very consistent in his message about you know, no concern at this point when it comes to inflation. Does the Treasury market support that in your view, the trade that we're seeing there? Well, certainly yield. They're extremely low. So in that context, yes, absolutely. The Treasury market is signaling low inflation and environment. However, we have seen this steady climb and Treasury yields over the course of the last step three months or so. So does tell you that they're starting to price in better prospects for growth and what better prospects for growth comes a little bit more inflation, but by no means a lot of inflation. Just to rewind back to where we ended the discussion last Friday. Carol, Basically the U. S labor market is in deficit about 11 million jobs, which means it will take a very considerable period of time or else some dramatic off the charts. Payroll gains this year to re absorb that labor slack. And as long as that flack is out there, then there's not gonna be a lot of pricing power for workers, and if workers don't have pricing power, then they can't tolerate higher consumer prices suddenly see pockets here and there of demand their supply disruptions that lead to higher prices for certain goods. But the overall inflation picture is really limited by workers incomes until we re absorbed that flag that we've got, you know. Ah, lot of disinflationary. It's not outright deflationary pressures in the economy, right and safe to say right now there's a fair amount of labor slack. Unfortunately, in the economy, all right, Carl, we're gonna leave it on that note. Listen, thank you so much. I really appreciate getting your thoughts There are chief U. S economist with Bloomberg Intelligence. Or call Rick Adana. Would you want to get back to your top business Stories? Also check on that trading day. Let's turn things over to Charlie Pelant. I feel like there's a little bit of firming the operation right about that final are.

Jay Powell Carl Fed Carol Loud Treasury Rick Adana Jackson Hole Charlie Pelant Biden Bloomberg Intelligence flack U. S Karl
"carl i" Discussed on Back To Back

Back To Back

05:48 min | 1 year ago

"carl i" Discussed on Back To Back

"Is this your studio in Detroit is this like a complex you live in? ? Do you have a separate studio? ? Built a a built room in the backyard. . So onto the back of the house, , I had the guy who <hes> whose company who originally designed Electric Lady Land Studio else I'll add <hes> his firm did the did the <hes> design? ? Architecture so they did the whole. . The whole space. . So it's almost like another building mess right on the back of the House so We, , we call it an extension, , but as you know, , it would be like A. . Size of of maybe a small party store or something you know candy shop if it was in the building by itself nearby, right? , ? Yeah one it's I think it's good to have a separate space mentally. . Just do something that doesn't feel like you're working out of your house just a separate. . You know that work life balance yes. . Go is good for me because. . I had a building. . <hes> kind of a kind of a not you allowed like a big Detroit building, , but it was you know a spacious building on its own. . and. . Not, , definitely. . Not In walking distance from from either where I was living when I when I got it or where where we live now. . But. . In in the sense of of <hes>, , you know a bigger city like New York <hes>. . It will probably take about forty minutes to get there. . But in Detroit time, , it takes about fifteen herreid. . So so relatively close in comparison to. . Other cities stuff and. . That one was like. . It was like running a boat. . Because you can be in one side of the building and it's raining and you don't even know that is coming through the other side of building and we had that on on many occasions where it would just you know it would just pour through. . We had damaged records. . We had <hes> kinds of things and and <hes> you know the the the Detroit. . I think is always to you know own a big building because. . The cheap in Detroit rather still chee even though the <hes> the cost of them went up there still still very cheap. . and. . You get into owning a building has five floors. . Floors and you can't even use a quarter of it. . But you know you have this big as building. . So it's like <hes> you know buying a Rolls, , Royce? ? And maintain it right exactly, , and then having to maintain it. . You know. So . you're. . You're <hes> rolling around town in this big ass. . Rolls Royce is not really necessary good roll around in a you know a a a s quarter. . Something smaller. . Yeah. . I mean it's interesting that we're talking about spaces and creative spaces. . Because I was actually just reading that your <hes>, , your art installation just reopened now in New York and I was reading up about you know the space that that's in for the people who don't know united in. . A converted Warehouse Space and Yeah I was just thinking about like. . repurposing spaces in how how reuse spaces and how that's tied into your music and Techno Music in general I think techno is a lot about Rican text to allies, ing , sounds and spaces, , and maybe just to start off or anybody who doesn't know what is the party after Party installation exhibit that you did. . A project. . which is a beacon which is. . CONSIDERED UPSTATE NEW YORK In some way but I think it's called Hudson. Valley . is is what it sounds so so <hes>, , they have this big. . <hes> former box factory, , and I think they used to make boxes of packaging Nabisco or or something like that so you know it's it's A. . Really a gigantic again space. . <hes> with multiple. . Rooms. . My favorite room is <hes> the Warhol Room that's got a a beautiful. . <hes>. . A series one series of Warhol, , goes all the way around the whole room though <hes> world ms probably five thousand square feet or maybe even more you know so. . My piece is not directly below it but. . <hes> but below it in in what's considered a basement and they usually have like Dan Flavin pieces down there light the light installations from Dan Flavin and in another part of of the basement, , there is a big flavin wall this that's down there and glows neon. . And <hes>. . My Room is A. . Mighty. . Twenty thousand. . Square feet maybe and a lot of columns. . And <hes> a lot of windows and <hes> when I first saw of course there were all these these ideas that that will come into mind you know it definitely is going to you know rave back in the nineties

Carl Craig Detroit New York Dior Beacon Gallery producer Kate Elsworth Willie joy
"carl i" Discussed on Born to Impact

Born to Impact

04:30 min | 1 year ago

"carl i" Discussed on Born to Impact

"This concept of ballots. There's a lot of people who are out there. and. Perhaps they're like me back in the day where they're just starting and I was working as a fulltime teacher and I was trying to get business off the ground now granted I'd have younger and have a family at that time, but there's some people all three going on the day job, but trying to get off the ground Manley Life Right. For somebody like you call your. You're one of the busiest guys that I know in. That's not. I mean it's a great way you put your time into things that you believe matter. But somebody. Of who has grown into your notoriety and success. Has a lot of opportunities and then there's certain things that you're gonNA. Say Yes to. You. Say No to, but I mean granted I. Think even even for me and Dan will probably say the same thing. That as much as we say no to things, we still always have a full plate. So I, want to talk to you about. Somebody who would say. Carl I really. Feel like I'm struggling. Families get attention that they need, or this is not able to get attention. That's just have too much going on if you're overwhelmed. I don't have time. How Sin Twenty four hours herbals. How can I live a more balanced life or how? How do I have ta? How do you have time to do it? All you know and for somebody who says. Living a balanced life, you know or encourages people to live a balanced life. What's your opinion on this whole idea of a balance? Insignificant Question Okay, so. My semantics are going to be different here, but it. It helps me frame it so maybe someone learns the same way I do. I'm not a big fan of the word balance in the way, most people use it and the reason. Why if I go back to a mindset thing again because I'm a Christian. You know when Jesus talks about how we should live our lives. You will not find balance my brother like A. in fact, there's a the most famous sermon ever recorded is from Jesus and it's in. If anybody wants to check it out, it's every sermon on the mount. One of the things he says. Don't worry about your clothes. Don't worry about you. Know the little things in life. Look at the birds put feathers on them. Look at the sky. Put Stars in it. Seek first the Kingdom of God. And then. All of these things will be addity right? It's a mindset. There's no balance..

Carl I Dan
"carl i" Discussed on QUEERY with Cameron Esposito

QUEERY with Cameron Esposito

05:59 min | 1 year ago

"carl i" Discussed on QUEERY with Cameron Esposito

"Of fundamental fundamental experience for me as a professional rate of course as a teacher but also as just a queer person in the world Yeah Yeah I learned a lot. Wow you know I actually have a just a little bit of malaria with a population that you're talking about I after school after college. I I worked at data. I worked at a charter school as a tutor which then kind of got me into the school system? And and then I went and worked at a A school that was just for kids. And this is the work that the school used. I don't know like maybe now. The appropriate wording would be a handicapped but at the time people were using the phrase severe special needs so severe physical special needs was was how it was like even written about on their Their language and the things that the parents and the kids used. So it's it's I don't know the answer on updated language there but because I was having this familiarity with the school system and I was also or with different school systems. And I was also doing doing Improv at the time Improv comedy. I see my girlfriend was a social worker. And she worked at a she worked worked at she would use the phrase residential treatment facility but it was What you were talking about? It was not Not simply kids. Who couldn't be placed in foster care but but some some youth who were Serving time yeah and I would go there and teach them improv classes. Yeah it's incredible. It was incredible. It was incredible and This was actually all all female was the it was for juvenile female sex offenders And so I would go and you you know again. This is a lighter Set of involvement in these people's lives but it was is very apparent to me that this is like mostly folks people color. Obviously the other thing that really it is true because then I eventually worked at a then. I eventually worked at a at a group home slash treatment facility city and the other thing that I don't think we talk about is how if like you're a young person in this situation Mutt like the percentages are very very high. That that this is generational for you And so that is another thing that makes it very It's tough to then interact with somebody being incarcerated straighted for something. They're a minor. This is something that happened to them. They're generally generational acting out the way that they know how to interact with people and then we as a culture are only responses to that we know of now is to just like you know isolate and try to redirect or punish right So I can really imagine that that that would be a lot to see for somebody Because I felt very impacted five these apperances and and seeing these different ways that you know How how different young people grow up and ways that if you fall all through the system You can get really stuck site. I go ahead all is just going to say thank you for sharing that with me I guess you're sharing it for the listeners. Also but I I appreciate you know I think a lot of us who are connected to fields where we are you know building connections with people and and and giving care to people Have Been In. These have worked these kinds of jobs and I was ill prepared. I mean by I and I had a pretty decent teacher education but I was not prepared to deal with as as you as you really aptly described the generational trauma of incarceration in the fact that For a lot of the families of these young people. They weren't aren't they. They were not being given other Options to help care for their children right except for like certain authorities and certain justice systems uh-huh and those systems are really geared to funnel people in a certain direction So there were a lot of youth there. I mean when I say adjudicated as sex offenders I think people's is kind of bullshit out and they get really Afraid and not sure what that means. But you know. We're talking about things where and I'm not trying to minimize any kind of inappropriate hit Sexual behavior but you know I'm talking about kids. Were there for things that were bona fide sexual assault and all on the other end of the spectrum like an inappropriate Touch on a bus rate and they would be literally in the same facility getting the same kinds of treatment And and there didn't seem to be a lot of recognition about the varying kinds of interventions that that folks need Or that there was a way to help them. That didn't focus on incarceration so I learned a lot of this after the fact In the moment it was just very it was a lot to just process Every night at home with my partner and with my friends and family and You know I I really transformed the way I thought about who who gets educated in our country and how and why and and It just gave me great insight.

malaria assault partner
"carl i" Discussed on Girls Night with Stephanie May Wilson

Girls Night with Stephanie May Wilson

02:37 min | 2 years ago

"carl i" Discussed on Girls Night with Stephanie May Wilson

"Like, but that he did not notice. But I think that we all their things that were like, that's the guys driver grows job, whatever there are a set number of jobs that have to be done by every family and Carl I think felt frustrated with me because I really wasn't carrying by weight in some of those specific like household kind of things. So we sat down at one point. Really? Okay. What's yours was does that too? And Carl is we come the laundry fairy because I wake up in the morning, and my laundry is done. I need like. Laundry, but he gets them sort of like satisfaction of. It's just sort of the monotony of in getting things put away I kind of like the dish wash. Art, he doesn't like doing that. And so like, I feel like we we each took our things that were better at than there were some things left that neither of us wanted to do. And we each pick some of them. So my things even though I was not gifted in these areas all was keeping track of our budget. I just inborn like task oriented everyday like that's why I keep track of our budget Carla's all big money stuff. I make sure we have groceries in the house somewhere or designed tonight. We're going to play I sort of cook for us. I think we're bed. It's not my gift. But I know that Carlos so many other things that that's one of the things that was left on the table. And that's one of the things I took. So I think like figuring out what is your thing. What do you care most about or like, you know, you're going to have to take things that are not your favorite thing like health insurance and just deciding who who's in charge of that and communicating all wiles. Yeah. We definitely did that. And I I think I underestimated the amount of work that outdoors is I don't do any of that stuff. And I didn't even get credit for it. Like he's out there trimmed hedges cutting the grass doing having a whole day of stuff. And I'm inside vacuum. You've never cleaner to literally yesterday, I'm cleaning behind the sink in our guest back and sending still thirds of he starts cleaning it, and he's like, I don't think this is ever been cleaned by it has been gleaned. A lot is never been cleaned by never not. I don't think he's ever scrubbed toilets. Just never. He's never done this. I'm totally glove to acknowledge or anything that's outside that he does. Now. My my bad sorry. But yet you do list and compare. Yup. Yup. And each you'd have to take things some of like, some of the things you have more of skill for some ends, you don't than you just figure it out. So I've got a couple messages from women. Actually who said we thought. On our honeymoon is that about sign..

Carlos Carl I Carla