11 Burst results for "Brigham And Women's Hospital"
The Readout Loud
"brigham women hospital" Discussed on The Readout Loud
"That model is broken. Because that model requires rigorous adherence over decades, it requires regular healthcare access over decades and extensive healthcare infrastructure. All of these are really in short supply. And as I said, we think that model is broken. And we think the solution is a safe and effective, one time treatment that leads to permanent lowering of LDL cholesterol. So imagine at the time of first heart attack, the cardiologist treats that patient with a one time interventional permanent procedure to clear the clogged heart artery that's a stent, and also at the same time, delivers a second one time procedure, a 60 minute IV infusion of verve one O one to safely lower LDL cholesterol lifelong. This is the future we're working towards. Say, what's your thoughts about the need to show durability of a treatment like the one you're developing? That's kind of the durability of any sort of gene therapy or genome editing treatment has been an issue. How long do you have to show the effect? And what outcome would regulate or want to see? Do you feel like just sort of extended cholesterol lowering is enough to get your treatment approved or are you going to have to show some sort of outcome? That's a great question. Our current expectation is that the registration endpoint for verb one O one is LDL lowering. To date for every treatment modality that's come along that lowers LDL, particularly by the PCSK 9 mechanism, LDL has been the approval endpoint. Now you ask about durability and yes, we expect to show durability. So by the time we get to a BLA, we'll have durability data probably on average four years. Maybe even up to 5 years for some patients. And so the preclinical data to date strongly suggests that gene editing is going to be very different than viral vector gene therapy in terms of durability. And the reason this kind of gene editing is different from gene therapy is that we're making an edit to the endogenous DNA. And it looks like the cells that are responsible for liver regeneration. So the liver does regenerate, are actually edited when we first do the editing. And when they divide to give rise to new liver cells, they're carrying forward the edit. And therefore, it's durable. In addition, unlike viral vector gene therapy, we don't have issues around an inflammatory reaction to the exogenous virus or we don't have a requirement of ongoing protein expression that's needed for therapeutic benefit. So cardiologists as a group have a well earned and I think warbly referred to reputation for being pretty opinionated and very confident in those opinions and unafraid of sharing them. So I was curious what kind of feedback positive negative are you getting from all those chatty cardiologists Friends of yours? We do tend to be opinionated and one person's opinion that is carry a lot of weight over the last few decades. Is doctor Eugene braunwald. At the Brigham women's hospital. And as you know, he's a leading figure in world cardiology and the editor of the definitive textbook for the field called Braun wall's heart disease. He had two comments actually a couple of days ago after the verb one O one first patient dosing was announced. One is the lower the LDL, the better, and you can't have too low an LDL. The problems only how you get it down. The second comment was really on gene editing, and he said, to quote, so gene editing is the big stick because it's a one and done. It's a very big deal because Atlas card at cardiovascular disease is the most common cause of death in the industrialized world, and LDL is the primary reason. So. I think his comments really reflect the unmet need and the potential solution here. We'll take this work is really fascinating and we look forward to having you back on the podcast when you've got results reading out from the study. Thanks so much for joining us today. Thank you, Adam. Yeah, we expect to have data. Clinical data interim clinical data on this phase one study in 2023. All hot girls have IBS, just so you know. That's abbreviated JS yk. And that's a tweet from at piece of crust posted on May 16th, 2019. I mention it because it is one of the earliest examples of an in joke among the extremely online that grew into an unintentional movement for people living with chronic conditions. It helped clear the way for conversations about health, seeking out care and advocating for oneself in the doctor's office. Stats Isabella cueto got extremely online to document the hot girls have IBS phenomenon. She's going to explain it to a grandpa like me. And she joins us here to talk about it, Issa. Welcome back to the podcast. Thank you. Thanks for having me and especially to talk about this. Well, so maybe let's start with the origins. I assume people know that IBS is short for irritable bowel syndrome. But they might be curious as to just how it became a sort of tongue in cheek membership card for people on social media. Can you explain? Well, I try to explain, but like a lot of things on the Internet, it's extremely hard to figure out how or why something takes off and why it happens at a certain point in time. Since much of the Internet is just memes within memes, just Russian dolls of memes. So I suspect this is my theory that it's sort of like a combination of people getting really into WebMD and finding out health information online, and then the rise of Megan Thee Stallion, who I thought I thought my story was the first in stat to mention Megan Thee Stallion, but Damien, you actually had her in one of your stories. So I'm jealous. That's a side note. And then we have the pandemic, you know, mental health conversations happening online. We have like tummy trouble memes coming in, and then at some point we sort of wind up in this space of puck girls have IBS and that's sort of the trajectory that I've been able to trace by being online. So like a lot of things during the forest indoors period of the pandemic, the phenomenon quickly made its way to TikTok. Hot girls have IBS.
WGN Radio
"brigham women hospital" Discussed on WGN Radio
"Number if you want to join the conversation and I'm going to get to that other study that I mentioned 8 6 6 5 O 5 four 6 two 6 8 6 6 5 O Jimbo Fascinates me that this is what it's at the top of this study website I look at Political mortality gap people living in Republican counties are more likely to die early This is coming out of Boston If you're in Boston give us a call I don't know how reputable this is You let us know Most voters probably know if they're living in a red or blue county they might live longer This new study finds that the choice may come down to whether Republicans or Democrats control your county Researchers from Brigham women's hospital have discovered a growing mortality gap in democratic and Republican led counties specifically the team found that death rates decreased in Democrat counties by 22% between 2001 and 2019 During that same time period the death rates and Republican counties dropped only by 11% Well that's pretty old data and great It's longitudinal It goes from 2001 to 2019 but I would love to know what the mortality gap looks like after 2019 because in particular 2020 2021 2022 especially 2022 because this is when things are really getting into the thick of it right This is where things are getting really hot and heavy We're not in great shape over here But I want to go to who is my caller here Doc and Wilmington Delaware Doc what's going on you're on with rich Valdez Welcome Rich you are welcome brother fresh air and Jim has to leave For any reason they make you the new host I would be totally satisfied whether I'm a long time Jimbo car and it's a great pleasure and an honor to hear you on the rarest or your greatest Let me give you let me give you a couple thoughts of mine almost going on and I'm a racial Republican I want to see Republicans win But here's my thoughts What I'm hearing from people in the my state of Della which is the deepest blue state is that people are fed up with the Biden administration even in Delaware due to the reason rich inflation People are worried about inflation But here's where I think Republicans I want your thoughts on this because you're a Tino American I want your thoughts on this I think we can really hurt ourselves as Republicans in the general on two issues Guns and abortion If we go too far on guns I'm a gun guy in the general and if we go too far rich on abortion and deny women their right to choose I think we would lose this whole thing in 2022 and 2024 Your thoughts sir Yeah well thank you for that I appreciate that Number one I think guns and abortion honestly are never really on the ballot although they're kind of always on the ballot But in particular abortion that's going to be figured out in a couple of days That leak was pretty much after a vote was already taken from the justices So there's a very slim chance that that's going to change So what we saw leaked is likely what's going to happen in the next few days because they're going to wrap up their session right now So I think that's actually going to happen And that's why the National Guard is on full alert and this is why Biden is saying there's going to be a mini revolution and I have audio of that will play that That's what he said on Jimmy Kimmel last night The president of the United States is expecting there to be a mini revolution but this is any time things don't go right for folks that are left leaning I think that's always the case Brace for the riots get ready They're going to tear things down They're going to loot they're going to pillage they're going to burn things So ultimately I think that's what we can expect And if it happens over the summer another ugly bloody summer that will definitely be out of our system by the time November comes around because people are broken You said that That's how we started this right People are paying more for everything And I think people are ultimately going to say look you know I love my right to choose or I love my right to life and I love my right to the Second Amendment but what I love more than anything is the ability to pay bills and I love my family and going on vacation and spending time and sending my kid to a good school So I think those things are going to be overpowered by the economy Clinton was right or I should say James carville the raging Cajun when he said it's the economy stupid That's really it It really is I think people won't be able to see past it Most people in life that I meet And I'm pretty sure you two Doc that you meet When you ask them things they're like oh yeah you know I like this team or that team or you know I do this or I do that But they're not necessarily hyper partisan political people Most people in fact say I'm not really into politics I don't care It's either crooked or crooked I don't care either way you know You're screwed either way And ultimately I think that's the majority of people are independent and disaffected and they don't care There might be some more now recently that you know as politics has become a little bit more of every day everything You can't even listen to the hip hop morning radio station think you're gonna hear some rap music without getting a lesson in politics on a music channel So I think politics has invaded the airwaves and of everywhere It's into everything in culture But ultimately that's my thought on it is that those two things are divisive and they get people to pick a team but I don't think it's going to change the outcome I don't think somebody's going to say we're going to vote for more instability globally We're going to vote for more inflation We're going to vote for higher gas prices We're going to vote for less baby formula I just don't see people lining up to do that If anything they'll stay home That's my thought Doc.
Boston Public Radio Podcast
"brigham women hospital" Discussed on Boston Public Radio Podcast
"Dr troy had one more question about the television side and actually relates to what you were just talking about that These shows obviously want to create trauma and compelling stories that really draw people in but what some of the resistance you found knowing what you might be facing what you just talked about. So the the the grim realities the for lack of a better term the drama. You might be facing this winter. What's the resistance that you face when you bring some of those stories to the producers and how much they actually are willing to reflect given what you experience. I think what we see in the intensive care unit particularly at brigham women's hospital where we're affiliated with dan. There is there is so much sadness and in those moments of sadness there's also great grace and beauty and love but there is a lot of sadness and i think that it is hard for people to view multiple stories that leave them devastated that leave them. Sad people don't largely turn on the television for that. And so until. I think that i think that. In order to try to put across any amount of education or information The producers people who i worked with as this show have taught me that that this isn't a documentary That that we can reflect some of the reality of the hospital. Some of the medicines race in the setting of terminal illness but that we also have to give people hope for them to continue to watch. And and i feel that i can understand that and so i think that that is that is a balance that i'm always trying to navigate but one that i am hopeful that we come out on the side of giving people a reason to keep watching but also leaving them. Something that's real as well your doctor. I've thought many times during this whole pandemic that what we see of patients in the hospital is largely these very clinical pictures of people in bed with the ventilator all these machines they're attached to but we don't see what i read about. Which is people gasping for breath and and waiting to get attended to and the suffering that goes along with cova off. I know that they are obviously who wants to have one of their loved ones. You know in shown on any kind of video suffering the other hand. I've often thought if we saw that maybe so many of us wouldn't be so cavalier and say oh well you know. I'm young and healthy. If i get this. Now it'd be deal. Can you talk a little bit. Because i know you were very involved with covert patience right from the start it is. It is a big deal to gasping for breath..
Boston Public Radio Podcast
"brigham women hospital" Discussed on Boston Public Radio Podcast
"In life particularly amid a pandemic who does not want to have the opportunity to do a do over to go back in time and make things right the world of todd production when things go. Wrong industry lingo goes. We can fix that. It's a phrase that has a lot of resins for dr daniele llamas. She's a pullman Pulmonary and critical care physician at brigham women's hospital and in her spare time a co-producer on the tv medical drama. The resident in your latest piece for the new york times she writes about how the grim realities of being a physician are always the ones that should or need to make it onto the small screen. Either with us. Or she's about to be with he's about to be with us. Joining momentarily momentarily is danielle lamps and really anxious to talk to her. But you know something bar waiting for her jim night intruder before and she's done all this research about people in icu. Care in hospitals the trauma that they experience getting out of the icu assuming they survive alone. Tragedy don't survive. But how is they have nightmares about what went on there They they don't remember. They come they come back and take towards the icu so they can try to recollect their time. The issue it's amazing. It's groundbreaking so eager to talk to her about this. Because i was reading some of this. And i find it absolutely fascinating especially the people who want to go back and really understand what they went through also very eager to talk to her about she. Joining us now is that we're hearing from from our producers about the television shows. Are they as accurate as they seem to be. With all of that rushing around on the sets and the beeping and the tests and it seems like they are one of theses is that tv can teach us a lot about medicine because we have a lot of misinformation about About about medicine and the nfl that We're gonna talk to her about too. Is the idea of these miracles. That occasionally happen and i. Oh we're not. I'm not going to tell you because she's here and she can tell us. Okay you're late dr but we're glad we've got you better late than never right. I'm happy to be here. Thank you so much. Thank you so much for joining us again. We were just talking about what you mean. I talked to you before about your work with people getting out of us but if we have time to get to that too. We already talked about that. We've did want to talk about your kind of moonlighting job in your there at the hospital. And then you're helping a production of a tv show so tell us about that and what you've learned about doing both yes so long. Been an avid viewer of medical television. Dramas which is perhaps slightly unusual characteristic for a physician. Often people find him insufferable because of medical inaccuracy. But i love them and then trusted them. Not just for the drama but interested. Broadly in how medicine is portrayed to the public. And so you know for those two reasons. I found myself drawn to the are. I've seen all of those episodes multiple times and even all the current ones including great. I've watched all of that..
The Munk Debates
"brigham women hospital" Discussed on The Munk Debates
"Options. And that's why we need to take this opportunity serious. You can prevent global warming unless china is part of the solution is not normal male. Behavior this predatory behavior all of that was thrown away in those eight minutes and forty six seconds. And that's the moment that i became an abolitionist. Extraordinary claims require extraordinary evidence. Welcome to the munk debates on every episode we provide you with a civil and substantive debate on the big issue of the day to arm youth the listener with enough information to make up your own. Mind today's debate. Be it resolved. The future of mental health is big data. Basement announced it will start using artificial intelligence to help identify when summers expressing thoughts. About suicide on your b- we comes. It's a new smartphone. App collects millions of data points. About a patient's behavior tracking their movements phone calls texts. What we have our exciting front of ai. There's so many metrics that objectively can help at a real time basis tap into a person's state of mind flow. I'm your moderator. Roger griffiths while those are just a few of the growing number of algorithms tracking our mental health that some experts say could revolutionize the field of psychiatry bring quicker and more effective diagnoses to millions of people in need of help. Instagram posts techs logs. Google searches activity. Trackers will all supposedly usher in a new era for psychology where clinicians will be freed from patients memories and maybe even more importantly from their own inevitable human limitations and biases critics. Say the problems with this. Big data approach go far beyond the obvious privacy issues that could come with outsourcing mental health monitoring digital oligopolies like google and apple the push for mental health algorithms reflexive reductive view of human emotions. And it has the potential to fatally undermined the traditional human centered field of psychiatric medicine. Diagnoses based on dialogue between two individuals grounded and intuition and empathy will always be better than machine intelligences in terms of drawing out personal histories explaining trauma and generating helpful treatments on this installment of the munk debates. We challenge the essence of these arguments by debating. The motion be it resolved. The future of mental health is big data. Arguing for the motion is daniel baron. Medical director of the interventional pain psychiatry program at brigham women's hospital. He's also on the faculty of harvard medical school and as the author of the recent bestseller reading our minds the rise of big data. Psychiatry arguing against the motion is gerhard gruner professor of psychiatry and head of the department of molecular neuro imaging at the central institute of mental health in mannheim germany. He's the author of his own acclaimed book. How do we want to live. Daniel gerhard welcome to the munk debates. Thank you for having us. It's great to be here. Well thank you both. This is a really interesting topic that i think Challenges us to think through two different key features that have shaped much of our experience collectively and individually this pandemic and that is technology and and mental health. So the opportunity to kind of explore the intersection of these two kind of important social trends and features in our day to day lives is really a privilege and an opportunity indeed. Our resolution is simple to the point. Today it's be. It resolved the future of mental health is big data. Daniel your arguing in favor of the motion. i'm gonna put a couple minutes on the proverbial show clock in turn the program over to you. Thanks for your. I'm pleased to affirm the resolution. 'cause i believe that not only the future but also the past president of psychiatry is big data and so to give us some perspective. It's worth noting that four millennia clinicians like myself and gerhard have sat with patients. Ask them questions by carefully observing. How and what they say. We've gathered data about what's wrong. In fact the very first recorded medical texts back in ancient egypt the medical papaya they described procedures for listening in organizing clinical data and then deciding to act benefit the patient. This is clean exercise and big data the difference between our assessments today and say what king tut's family physician bentiu would have done in thirteen hundred bc simply technology physicians today that are instruments and give or take thirty five hundred years of medical knowledge on and especially in the last hundred years technology and big data approaches in healthcare have led to this blossoming in the medical sciences and clinicians to detect things that are otherwise invisible for example we use electric cardiograms to measure and trace the flow of electronically through the heart muscle. We use molecular sensors to detect oncogenes. That can you tell us which treatments may benefit of patient in psychiatry. We don't spend nearly as much time measuring as other disciplines. And i make no mistake. The problem isn't that. I speak with and listen to my patients. Every doctor every specialty does that either. The only instrument that i used to gather data that i think is clinically. Relevant is my brain. I don't measure the behaviors. I think are important treatment of psychiatric disease and yet it's likely you have one of the most sophisticated behavioral measurement tools ever design in your pocket. Or maybe even in your hand at technology like smartphone or risk sworn smart watches would allow us to instead of simply asking a patient how they're sleeping to measure the duration and quality of that sleep. We're instead of simply listening to someone's description of their mood. I could analyze the patients facial expression voice the way their ideas flow onto another things that my brain simply can't detect types of signals that are too subtle for even a trained observer to attend to and to make use of so. The tools that we're going to discuss today are still in the research stage in without question. There are valid very reasonable concerns about data security and privacy concerns which i should add apply any clinical tool that is used today and yet every other field of medicine has successfully added bigger and better data to improve clinical care and so really. The question is big. Data is the president and future of medicine. So.
America Dissected with Abdul El-Sayed
"brigham women hospital" Discussed on America Dissected with Abdul El-Sayed
"Thank you so much for taking the time. I'm really excited to have you on the pod. This is the topic that keeps on giving man. It's just it's such a fascinating story. Yeah it has been. It has been a very interesting few weeks for sure. I can imagine your life. Well thank you for a leadership. Be sharing with us. Ready to get started for sure. Yeah absolutely Can you introduce yourself with the type shore. My name is aaron kessel. Hi i'm i'm a An internist and lawyer and a professor of medicine at brigham women's hospital and harvard medical school. Dr aaron kessel. Hyme is one of the country's top experts on pharmaceutical policy teaching at harvard medical school and chance full of public health. He sat on the. Fda's advisory panel which overwhelmingly voted against the approval of algae home just months before it was approved after the fda ignored the panels decision. Dr kessel along with two other colleagues resigned from the panel. I reached out to him to help us understand all the contours of the decision. And what it means for the future of the fda and prescription drug affordability in the us overall. Can you tell us about how a drug usually goes through the approval process. Sure well you know about sixty or so years ago. We decided in the us that drugs prescription drugs should be tested For their effectiveness and safety before they are allowed to be widely sold by manufacturers and so as a result of that decision Now drugs go through a relatively extensive testing process that starts with early testing laboratory testing and then eventually moves in two human clinical trials and then it goes through a process of clinical trials. I usually in healthy volunteers to get a sense of of what a safe dose of the drug might be And then eventually gets tested in patients who have the disease in order to determine what affects the drug has and what safety profile is and then ultimately that massive data get submitted to the fda and if the benefits look like they outweigh the risks than the fda will approve the drug for widespread use and presumably right when we talk about benefits..
The Ortho Show
"brigham women hospital" Discussed on The Ortho Show
"Once again it is just unbelievable. The guests that we have on the ortho show. We bring you dockery antonio in this episode. This woman is on a mission. She does not sleep. She is a professor at harvard medical school at the brigham women's hospital. She has literally three hundred peer reviewed articles. She's got forty five books in chapter. She's only been clinical practice for seven years. She is an outstanding surge in and and outstanding researcher which is so incredibly rare. She has so much energy we laugh. We have fun. Hers is another amazing unique story. I know you're gonna love it. I.
Cardionerds
"brigham women hospital" Discussed on Cardionerds
"And wait and wait reduction. We've done several studies. One who first authors tetreault who's also electro physiologist at brigham women's hospital and she published a very important study in jack. Where we showed in bunks women. Even being slightly overweight had elevated to risk of fibrillation. And then if you lost weight you lower that risk. And in addition some of the other research we did was around. Exercise and showing that exercise is beneficial to atrial fibrillation. But as we all know too much. Exercise can actually have an adverse effect and this again was a study that was done by tony acer who was also an electro physiologist and his now at nyu worked with me for a while. So both of those manuscripts were very important. With regards management of atrial fibrillation. In addition we also published one of the first studies looking at alcohol intake and h fibrillation. Now there have been multiple multiple studies showing that alcohol is related to atrial fibrillation. And as you know a randomized trial now that shows that if you abstained from alcohol you lower your risk of atrial fibrillation so all of these studies are not just by myself but multiple. Investigators have really changed the practice where we as clinicians think about lowering. Risk factors as electra physiologists event and approach sanders. Work in australia really took it to another level by actually doing clinical trial in showing that reduction of weight and modifying risk factors lowers incidence of atrial fibrillation. So now it's really one of our pillars of treatment and it is rewarding to see something go from observational research to clinical trials in actually to practice got is fantastic and so inspiring so many key findings have directly impacted our clinical management of arrhythmias in all of our practices. It's interesting speaking of lifestyle modification. I myself have converted to a plant based diets and starting cardiology fellowship. I have to blame slash credit by husband. Couldn't tell the interventional pain doctor for paying the most attention to cardiovascular prevention and converting our whole family's diet richard i can definitely relate. I myself went vegetarian because of my wife and recall. Actually how hard of all things it was to give up. Panda express have no disclosures new relationship with express hint so dr albert. We've heard so much about the beneficial effects of certain diets on coronary disease and really discusses at length as part of our esp preventive cardiology series. But i was curious about which diet or diets you recommend to patients with heart rhythm disorders. That's a good question. You know one of the first studies that i did when i was actually an ep fellow working at m. g. h. was to look at the association between fish intake and sudden cardiac death than we found that there was an inverse association and others after me and also found similar results. And you know. The american heart association has recommended that fishing take is important is a healthy heart diet and i do believe that and i do recommend that now a take off of that was that maybe people should be taking fish oil and in fact there have been some randomized trials suggesting benefit on death but others that than were smaller that did not show that benefit and with regards to atrial fibrillation. We recently presented a trial at the american heart association where we looked at random izing visual to twenty five thousand people and looked at atrial fibrillation and did not find benefit as you know. There's some studies suggest that there may actually be an increased risk associated with america threes. So there's a lot of controversy actually on that specific topic right now but regards to your question about what i would recommend to patients. That hasn't really been a good diet. Harry trial or one. That's conclusively proven that a specific type of diet lowers your risk of atrial fibrillation for sudden-death. There is the says he's with fish and also the mediterranean diet has been a we published on that as well socio with lower risks of sudden cardiac death. So in general..
Cardionerds
"brigham women hospital" Discussed on Cardionerds
"Thought we could start by discussing some of your major contributions to the management of atrial fibrillation even since my medical school days. It seems like the emphasis. On lifestyle management for diseases such as atrial fibrillation has increased exponentially as we learn more about arrhythmia mechanisms and now we specifically screen patients for sleep apnea diet alcohol use et cetera. So from all of the landmark clinical research that you've conducted over your career. That's far could you. Maybe summarize for us. What you feel are the biggest takeaways whether in eighth hundred prevention or in any of your other areas that sudden cardiac death. Thank you when i started doing. Research on the epidemiology of heart rhythm disorders really wasn't an emphasis as you say on. Risk factors for h. fibrillation or sudden cardiac death. And then you know a group of us not just myself but amelia benjamin in the premium study and patrick eleanor. We all started to get interested in looking at atrial fibrillation as you would cardiovascular disease and some of the major findings are really related to lifestyle and how it can impact each relation including body mass index. And wait and wait reduction. We've done several studies. One who first authors tetreault who's also electro physiologist at brigham women's hospital and she published a very important study in jack. Where we showed in bunks women. Even being slightly overweight had elevated to risk of fibrillation. And then if you lost weight you lower that risk. And in addition some of the other research we did was around. Exercise and showing that exercise is beneficial to atrial fibrillation. But as we all know too much. Exercise can actually have an adverse effect and this again was a study that was done by tony acer who was also an electro physiologist and his now at nyu worked with me for a while. So both of those manuscripts were very important. With regards management of atrial fibrillation. In addition we also published one of the first studies looking at alcohol intake and h fibrillation. Now there have been multiple multiple studies showing that alcohol is related to atrial fibrillation. And as you know a randomized trial now that shows that if you abstained from alcohol you lower your risk of atrial fibrillation so all of these studies are not just by myself but multiple. Investigators have really changed the practice where we as clinicians think about lowering. Risk factors as electra physiologists event and approach sanders. Work in australia really took it to another level by actually doing clinical trial in showing that reduction of weight and modifying risk factors lowers incidence of atrial fibrillation. So now it's really one of our pillars of treatment and it is rewarding to see something go from observational research to clinical trials in actually to
Cardionerds
Managing Atrial Fibrillation With Lifestyle Changes Dr. Christine Albert
"Thought we could start by discussing some of your major contributions to the management of atrial fibrillation even since my medical school days. It seems like the emphasis. On lifestyle management for diseases such as atrial fibrillation has increased exponentially as we learn more about arrhythmia mechanisms and now we specifically screen patients for sleep apnea diet alcohol use et cetera. So from all of the landmark clinical research that you've conducted over your career. That's far could you. Maybe summarize for us. What you feel are the biggest takeaways whether in eighth hundred prevention or in any of your other areas that sudden cardiac death. Thank you when i started doing. Research on the epidemiology of heart rhythm disorders really wasn't an emphasis as you say on. Risk factors for h. fibrillation or sudden cardiac death. And then you know a group of us not just myself but amelia benjamin in the premium study and patrick eleanor. We all started to get interested in looking at atrial fibrillation as you would cardiovascular disease and some of the major findings are really related to lifestyle and how it can impact each relation including body mass index. And wait and wait reduction. We've done several studies. One who first authors tetreault who's also electro physiologist at brigham women's hospital and she published a very important study in jack. Where we showed in bunks women. Even being slightly overweight had elevated to risk of fibrillation. And then if you lost weight you lower that risk. And in addition some of the other research we did was around. Exercise and showing that exercise is beneficial to atrial fibrillation. But as we all know too much. Exercise can actually have an adverse effect and this again was a study that was done by tony acer who was also an electro physiologist and his now at nyu worked with me for a while. So both of those manuscripts were very important. With regards management of atrial fibrillation. In addition we also published one of the first studies looking at alcohol intake and h fibrillation. Now there have been multiple multiple studies showing that alcohol is related to atrial fibrillation. And as you know a randomized trial now that shows that if you abstained from alcohol you lower your risk of atrial fibrillation so all of these studies are not just by myself but multiple. Investigators have really changed the practice where we as clinicians think about lowering. Risk factors as electra physiologists event and approach sanders. Work in australia really took it to another level by actually doing clinical trial in showing that reduction of weight and modifying risk factors lowers incidence of atrial fibrillation. So now it's really one of our pillars of treatment and it is rewarding to see something go from observational research to clinical trials in actually to
WBZ NewsRadio 1030
"brigham women hospital" Discussed on WBZ NewsRadio 1030
"Extraordinary physician, Dr Daniella Llamas, Brigham and Women's Hospital. She's a pulmonary and critical care doctor. She has been writing for the New York Times down for some time on she wrote this extraordinary piece. If you have a chance over the weekend, just tow Google it. I think to read the piece. Will really give you give you insight into what it's been like for these doctors caring for covert 19 patients and covert 1919 patients. Who are in extreme danger, The hopeful future and the patients who won't see it. Let's get back to the calls. Get as many folks in his we can going to go to piggy. In south Boston. Peggy Welcome your next on nisei with Dr Daniella Llamas. Go ahead, Peggy. Almost to talk to you, Director and get given teal feet while impatience. My nephew was operated on Friday. There. Exxaro operation. And he's a radio ologists down the Cape. His wife had a stroke. Last month. And it's Sunday. Uh, The intercept him best. Taken with My life is in New Hampshire, and he died off that cliff in 30 years old so I can come in. You can't visit anybody you know I created for in a couple of weeks. That it is a suitable I feel so bad cause Yes, it is a wonderful, wonderful guy. He just sent me a thank you know, before he went in the hospital, and he's done to his wife. Is called to the wink who I said she could hear him. And he went to see her before he went in Brigham Women's Hospital, but I don. I came here from Florida to take care of them, Rachel And I feel bad because you know nobody can visit you See if they're not neglected around, Peggy, I'll tell you this. I think if if you've listened and I know you've listened tonight I would hope that what you've heard Dr Lama say, and the stories that she shared with us, Uh, gives you complete confidence that your nephew is receiving Wonderful, wonderful intensive care in any Boston hospital, But particularly And tonight it happens to be the doctors from the same hospital where you were. Your nephew is tonight so Well, everybody, maybe we'll say a prayer for him. It does it look like he's going to pull out of this. This He is not covert related, obviously, right? No, I don't think so. Okay. Huh? That's a Z. I'm not. Er Thank you for all you do His sister. Is that your hospital? She's in the operating room Travel I was today. And my other niece is this practitioner in Michigan. Really you people So so, so good to while these people it's awful, but I feel so bad because I took care of my system and no juicy I kind of take care of the Marvin. I'll be 84 a couple of well, you just sit back and relax. And Peggy just sit back and relax and know that your nephew is is in good hands, okay? Yes. And we can promise that you know doctors, nurses, everybody, we we We are tender and, you know, make sure that people are lonely or scared and hopefully Before too long way. Hopefully your nephew gets better quickly, but before too long my hope is that the visitor policies will start changing some as covert numbers drop. So that's also a potentially hopeful thing. Because that has been awful. And I'm sorry for your family for so much loss. All right, Thanks, Piggy. And I got to get another call in. Okay. Thank you so much. We'll talk soon. Stay strong. Let's go to Kathy. An end over Kathy and hand over your own with Dr Daniella Llamas. Corretta head, Cathy. Dr Loomis. Thank you very much. Thank you, Dan. Um, thank you for all you, Diogo. Um, I was wondering if you could help me. Do some research. I I am allergic. I have analogy. Well, I think I have validated techniques to a tetanus shot when I was in high school. I tried to introduce my hands into the hands next door and I got bit. So I was told this week when I went to go get my coded vaccine that I couldn't get it because I had an allergic reaction to Tetanus vaccine. Um My primary can't position doesn't think it was actually a natural allergy. He believes that was probably the emotional reaction because Cause my mother hit the roof because she had to bring me to the doctors. They don't know how old do you can't be mad. Kathy, How old were you? 67. No, no. How old were you at the time that time? 0 17 16. Okay. My entire life I've never had. You know, I've never had a reaction to anything else any other? I've been getting the flu vaccine for 40 years. Um So the reason I was I was getting the vaccine early was because I volunteered with the senior center and I I bring people toe medical appointments and doctor's appointments, and I'm one of the few people that will drive to Boston. Well, let let's let's see what Let's see what Dr Lama says about your spent 15. It's been 50 years. Okay, let's let's let's listen to see what Dr LAMAs has to say. Cathy. Doctor llamas. I don't know you can't diagnose over the radio. I know that so we put you on the spot. Go ahead. Yeah. You know, I think I think the messaging about allergies in vaccination can be very worrisome. But also misleading. You know, I've I've heard of. Ah, actually, you know, a couple of sort of worries about Specifically the routine tetanus shot. Somebody had a reaction and covert vaccine have heard that anecdote from one other person on Bento worries that you know people have any reaction to anything shouldn't take the vaccine. At the same time. Uh, you know, hundreds and thousands and.