35 Burst results for "Boston University"
"boston university" Discussed on WTOP
"At Boston University. He says these bank problems shouldn't be a surprise. A surprise to many people how suddenly the banking crisis in the U.S. leaped across the ocean and appears to have been a precipitating factor in Credit Suisse's immediate problems. The Wall Street Journal, meanwhile is reporting that UBS has offered to buy credit squeeze for about a $1 billion. So what will become of the arrest warrant issued for a Russian president Putin from the International Criminal Court? Former CBS News Moscow bureau chief Beth noble. Neither Russia nor China, nor the U.S., nor Ukraine. Has ever ratified the International Criminal Court's founding treaty, so they're not really part of its system, making it easy for Russia and China to just ignore the indictment against president Putin and focus on the matters at hand. Putin was seen traveling in Crimea this weekend, which was illegally annexed back in 2014. He also visited Mario, which was seized by Russian troops in May. This is CBS News. CBS News is brought to you by Paul Gauguin cruises, artfully authentic, all inclusive year round cruising to Tahiti in the South Pacific, visit PG cruises dot com today. Ten O three on Sunday March 19th, 27° of windy chilly day behind the mid 40s. Good morning, I'm Luke lucard and the top local
Newsradio 970 WFLA
"boston university" Discussed on Newsradio 970 WFLA
"They gotta have a little fun with this. Come on, let the kids enjoy them. Now when they're warning parents. Yeah, that's what they're doing. That's their job. It's always to warn the parents. Some are calling it a great way to limit alcohol intake and avoid a hangover. Boston 25 new support of George Greta spoke with health experts who say the trend could cause more harm than good. Drink water today. We have Morgan, building on myself. Northeastern student Daphne Peterson isn't sure what to make of the new drink of choice on many colleges. Daphne is a liar. Daphne is a liar. They brought the cameras to and she goes, I've never done that, but I've heard of other kids on the campus doing the Borg, but not me. No, no, no, no, no. I have never done that myself personally. Some of these other bad folks do it. Which campuses known as the Borg, but could understand why. This kid on TikTok labeled his board. He took all the whatever would be on your milk gallon or water gallon, ripped those labels off and then just colored Borg onto there with sharpie letters. Okay, we got to write Borg on our board. For sure. We were going to need a market to write Borg on the side of our board when we create ours. This guy is a professional. He knows what he's doing. He has his orange looking though. So he's got a different mixer in here. I mean, he also what? Go outside my dude. He's inside drinking borgs. No, but where's the party? Hi, everybody. I'm here to do my science experiment of boarding. By myself. Are you saying borgin alone is too sad? It's a little bit boring alone is really just alcoholism. At a party, it's a little more excusable, I think. Let's see if he's got friends. And positive reviews. We'll do liquid IV and then they'll fill up the rest with hard alcohol and then water. The Borg, which stands for blackout rage gallon, is now making regular appearances on TikTok. Serious stuff. Some are praising the mix of water, vodka, a caffeine flavored enhancer and powdered electrolytes as a way to pace their drinking and prevent a hangover. Calling this a trendy. Oh, he's a doctor. This is simply encouraging more binge drinking. Oh my God. Yeah, duh. Always find the Doctor Who's gonna be all pissed off about this. It's better than if they were just drinking straight alcohol, isn't it? No. Why the alcohol's watered down? If you're drinking a gallon of it. Yeah, but it's got electrolytes in there. I'm not even sure what electrolytes do, honestly, but they seem good. Yeah, so you're getting hydrated. While you're having your alcohol. And then guess what? Every other aspect of college and drinking encourages binge drinking. Yeah. It doesn't matter what you're doing. Keg stand. Just different ways to do the same damn thing. And now they're focused on the Borg side. Be the jernigan professor in the Department of Health law policy and management at Boston University believes the popular portrayal of borgs on social media as the potential to put students in harm. Oh God. It's just inviting you to drink it. It's as if you were carrying around a bottle of vodka. It's just, you're carrying around with some water. The concern. I'm about tired of you. This guy's crapping on somebody having a good time. The doctor has to say that, though, because the doctor can't be like, nah, actually borgs are good. Two thumbs up from this Doc. I approve of the borgs. And then they get a bigger problem out of it. They can't do that so they're kind of trapped. At emergency departments across Boston, which see their daily share of patients dealing with complications from binge drinking. It can be on a Friday night. Another doctor, 30, 40, 50, 70% of our patients in the emergency department in downtown Boston is sometimes they drank 5 manhattans and sometimes they drank a board. Emergency medicine physician. Perception that Borg's are a safer method for consuming alcohol is not reality. And in my opinion, that actually makes it more dangerous because rather than say having maybe a cup of alcohol and someone saying finish your beer, you have a gallon jug. And now somebody is saying to you, you got to finish that gallon jug. Oh my God. This is always something new that they find. It's the choke out game. It's this, it's sad. It's just so dangerous and it's like wildfire, spreading across college campuses. You all did it too. Everybody did it. Everybody who went through that same period of life had had something like this. And how do you learn
"boston university" Discussed on WCPT 820
"Many of us rely on the healthcare system to keep us well. However, in his new book, me versus us, a health divided, doctor Michael Stein thinks we may be depending too much on medicine. This book is really a critique of all the things that were missing when we focus entirely on the healthcare system. It's remained a beginner on how to measure the quality of the care that we deliver. And it continues to leave out of insurance, which is part of the healthcare system in the United States. 20 to 40 million Americans depending on the year. Stein is a primary care physician and professor at Boston University school of public health. He says the first issue when discussing public health is that most people falsely assume it's just another synonym for healthcare. You go to any party or bar or have a conversation and you bring up the word health and a person will immediately start telling you their latest doctor story. So that's healthcare. They turn right to doctor stories. Public health, on the other hand, addresses preventable conditions, such as obesity, alcoholism, and gun violence. Stein refers to public health as all of the actions we can take before needing medicine or hospitalized care. He often uses soccer as a metaphor. So I think of healthcare that is the medical system as the goalie, the goalie is healthcare, which is you want to have a good goalie. If somebody shoots on your neck, you're the last line of defense. But most of the game is played out in the field by the other ten players. And the goal for those ten players is to keep the ball away from their goalie. Never go to the goalie. That's a great game, right? Never have your goalie make a save. The other ten players are public health. All the lifestyle factors we can control to keep us healthy. However, our current use of the healthcare system is like we've benched the rest of the players, relying solely on our goalie to protect us. In fact, we annually invest about 40 times more money into healthcare. We spend $11,000 per American per year for healthcare. So that's doctor visits, hospitalizations, medications, x-rays, tests, et cetera 11,000 per person per year. And what I would call public health, we spend $285 per person per year. Stein says our real goal should be to use medicine and doctors as a last resort. It's lovely to have a good doctor. We want that. We have good doctors in the United States, but the goal should be to keep the game away from your goalie. And so public health is all about those things that create health in the United States that keep us healthy. And they are the things you think about food and water and pollution and politics and discrimination and poverty and all of the sort of big issues that we face, some of us more than others, depending on the issue on any given day in the United States. And that's public health. Unfortunately, Stein says it's something we've continued to ignore. He looks at life expectancy as one measure of overall health, noting that the rates in America have become drastically different than some of our European counterparts. In the 1990s, the average life expectancy for an American was pretty much the same as it would be for a person living in Europe. And now American babies are far more likely to die before they turn 5 years old and American teenagers are far more likely to die before they turn 20 and American adults are far more likely to die before they turn 65 than almost any country in Europe. In other words, Europe has just better life outcomes than the United States across the board. Stein argues a big part of the issue is that our society values medicine more than actual health. Why are we spending $11,000 when we've reached a goalie when we're already sick? And we have to go into the hospital. And why are we not spending more than $286 per person on doing things like instituting policies that can change the way we remain healthy? In an effort to address a main public health issue, President Biden recently hosted The White House conference on hunger, nutrition, and health. The first hunger conference was held more than 50 years ago, and people like doctor Franz Al Hamilton are happy that policymakers are finally revisiting this topic. It's never been like high up on their list and now I think they're realizing that this is a real issue and it's so bad because the medical problems are so bad. They've had so many studies that come out recently that have shown that there's deaths in heart disease and related cancers purely related to our food. Hamilton is a bariatric surgeon, obesity weight loss specialist and founder of neuro switch weight loss. She says this year's conference aims to provide healthier and more affordable food through several different strategies. One is they wanted to essentially make government funding a food to include more vegetables and produce, not just kind of some of the typical things that they're able to get on some of the known WIC programs. They also have a lot of other programs that they want to introduce in the school systems to make food more affordable. They would like to make free lunches if possible across the states for children because a lot of times when they go to school, that's the only time they're able to get a meal for some people. And so they're wanting to be able to make that an option to be free. Many of this year's ideas expand on the outcomes of the first hunger conference, hosted by the Nixon administration, that meeting pushed for the labels that come printed on all of our food today, as well as many fast food chains providing ingredient lists for consumers. In an effort to build on these practices, Hamilton says this new conference focuses on the community's most in need. A lot of the changes that they want to make specifically focus on underserved and minority communities because that's where we're seeing the higher ratio of medical conditions. And so they are targeting programs specifically for those communities. The previous conference did almost like big picture stuff, which is great. I think that was like a great move. But then you have these certain types of communities that are still on government programming, having to buy certain foods because it's cheap. So it doesn't matter if there's a label on it if they can't afford to be able to provide or buy some of that stuff. And even after increasing access to healthy affordable food, Hamilton says there's still an educational component that needs to be taught. She can see through her own career how a healthy lifestyle can only be achieved if you
The Charlie Kirk Show
The Founding Fathers Were Very Clear About Separation of Powers
"Go back to the founding fathers, they were very clear about separation of powers and consent to the governed and checks and balances. Three branches equal any fourth grader that's taught civics of which they're increasingly not taught civics could tell you exactly the moral premise behind separation of powers. Starting in the 1920s, simultaneous, by the way, with kind of the regime of scientists and scientism is there was this fourth branch of government, where Woodrow Wilson, one of the worst presidents in American history, basically made an argument that the kind of founding fathers and what they said and what they did, that's old, that's outdated. We got to turn our back on that a new era is here. We have technology and we can govern men through different ideas and practices. Now, the implications of that is that an entire new regime, if you will, of governmental power and control was ushered in, that does not really fit into those checks and balances. For example, the power is no longer in Congress or in the executive branch, the power is in the deepest kind of chasms of the Department of Justice, the FBI, the Internal Revenue Service, the EPA, and you have this unregulated regulatory agencies that are unchecked largely unknown with unlimited power. And it's very hard to then check and balance it, and then you all of a sudden have very bad things happen. And you ask yourself, who actually voted for this? So for example, Congress should say, if you're funding gain of function research at Boston University, not only should he lose your funding, like you should be arrested. This is insane.
The Dinesh D'Souza Podcast
Researchers Have Created a Covid-Type Virus With 80% Lethality
"More lethal strain of COVID created in Boston University lab, researchers at Boston University have developed a new COVID strain with an 80% kill rate. And now let's think about this for a minute. First of all, an 80% kill rate, what? We're talking about 8 out of ten that get the virus die of it. Think of what this would do to the world that this kind of a virus were released. Now, I mean, think about how COVID got out. It now seems likely scientists continue to investigate or debate and not with sufficient intensity, by the way. Debbie and I often talk about this W is like, what's happening with the investigation of where this virus really came from? How did it get out? What were the motives behind it? Or was this just negligence? Did it in fact come for the lab from a lab? It looks likely that it did. It came out of the Wuhan lab, not out of a wet market. That theory, which was once treated as dogma, is now at least has a competing theory. And so here's the point, what are we doing with this gain of function research where we're taking viruses playing with them? Apparently what the Boston University researchers did is they took the omicron variant, and they took the original virus. The original Wuhan virus, if you will, and they mixed them together and they created in a sense a more lethal variant, which kills now it turns out kills 80%, not in humans because they are not doing human trials, but in mice. So yes, it's not humans. It's mice, but let's think about it when you give the omicron variant a mice. They have a very mild case of COVID, which means that that the reaction in mice is mirroring the reaction in humans.
ToddCast Podcast with Todd Starnes
The Things You Are Paying for at Colleges
"Should we have to pay for the gender studies majors and the goat yoga people? Is that a thing? It's a thing. Google it. It's a thing. There are some schools that are actually advertising infinity pools. You say, what is an infinity pool? Those are rooftop pools that make it look like you're going to swim over the edge. Which is a little bit. These are you would expect that at some sort of a high end posture resort, not the local university or college. But this is what they're doing. They're squandering our tax money. Who needs to go on a vacation when you can just go to college? Yes. Just do the actual campus that is. No, exactly. I mean, when you look at all the buildings going up, we're paying for all of that stuff. That's true. Michigan technical Michigan technological university. They have a campus on campus, ski resort. A 112 acres of ski friendly terrain. Pomona college. They have an annual ski beach day. They actually have buses that take the college kids to the beach and a mountain resort for fun in the snow and the ocean. Oh, that sounds like a lovely day. Boston University looks some of these schools are private, I get it. Boston University, 26 story glass dorm, a condo with private bathrooms, walk in closets, and you get your own complimentary flat screen TV. Pretty snazzy. The university of Missouri. You guys have a lazy river that runs through campus. There's also a sauna and Whirlpool, hot tubs, and an on campus beach club. There's also a racquetball court and various other full courts where endless games. This is unbelievable stuff here. The university of Wisconsin in Madison. The student union has a bowling alley, art gallery climbing wall, billiard hall,
AP News Radio
Demaryius Thomas Diagnosed With C.T.E., Family Reckons With His Death
"Demaryius Thomas died last December at age 33 The cause has not yet been identified but Boston University's CTE center researchers conducted a brain study and diagnosed the four time pro bowler with stage two chronic traumatic encephalopathy associated with progressive behavior cognitive and mood abnormalities His family says Thomas developed depression anxiety panic attacks and trouble with his memory in the years before his death Thomas played ten seasons in the NFL for the Denver Broncos New York Jets and Houston Texans winning a Super Bowl in Denver
Woodrow Wilson Curtailed One of the Pillars of Our Democracy
"Christopher B Daley professor at Boston University has written that during the lead up to America's interests the World War I the Wilson administration took immediate steps at home to tell one of the pillars of democracy press freedom by implementing a plan to control manipulate and central all news coverage on a scale never seen in American history Following the lead of the Germans and British well began to censorship to strategic elements of all out war Even before the U.S. entered the war Wilson had expressed the expectation of his fellow Americans which show what he considered loyalty Wilson started one of the earliest uses of government propaganda He waged a campaign of intimidation and outright suppression Against those ethnic and socialist papers they continued to oppose the war Together these wartime measures added up to an unprecedented assault on press freedom Wilson also created an elaborate domestic spy network to watch German immigrants and American radicals Federal agents arrested hundreds for making anti war speeches And sometimes for informal and private remarks Eugene debs four time presidential candidate for the Socialist Party Was arrested in June 1918 for suggesting during a speech The young American men were fit for something better than slavery in cannon fodder Sentenced to ten years in prison he defiantly ran for president in 1920 from his jail cell in Atlanta He received almost a million votes And during the war more than 2000 men and women were arrested for disloyal speech and over 1200 were jailed
Accelerate Your Business Growth
"boston university" Discussed on Accelerate Your Business Growth
"Matt started his career in the film industry with production and creative roles at Fox searchlight, Dreamworks Animation and Disney. He holds the BA from middlebury college and an MBA from Boston University. Thanks so much for joining me today Matt..
The Larry Elder Show
"boston university" Discussed on The Larry Elder Show
"Harvard Law. And he told me, and I'm quoting, I never got a job from a poor person. These are people who've gone to Harvard. People have taken courses, AOC has a degree in economic for crying out loud from Boston University. It's scary. Government's gotten bigger and bigger and bigger. Are the results any better? Remember when Joe Biden, when ObamaCare was sigh leaned in and said to him, it's a big effing deal? And now he's talking about high cost of prescription drugs and high cost of healthcare. I don't ObamaCare solved all that. The left thinks the only way for there to be cheap affordable healthcare. Is for a complete and total government takeover. Which will create shortages. Lessons in it for R and D, less than ten for innovation. They just don't believe the market applies to healthcare. And these are people who are running our schools. Running our universities. Making entertainment entertainment programming fair for us. They're in the media. And Joe Biden has the nerve to complain he's not giving getting enough positive coverage from the media. Are you kidding me? This man sits up there and says to you and me? It is multi $1 trillion plan will not cost a penny. They will decrease. The deficit. They will decrease inflation. Even as many economists say just the opposite. He still enjoys a nearly 70% approval rating among Democrats. Now that's down from the traditional 90 that they normally give them, but still 72%. I say again, half the country believes as a free lunch and at the other half is stopping them from eating it. Now Joe Biden says we have only 9 years left to stop global warming. Science tells us we have 9 years. Science tells us who science. Is there a guy named science who tells him Johnny science? Science tells us we have 9 years before the damage is irreversible. That it was ten. So my time travel results is my first four years as president. The jobs will create the investments we'll make and irreversible steps will take to mitigate and adapt to the climate change and put our nation on the road to net zero emissions, no later than 2050. So let's not waste any more time. Let's get to work..
Boston Public Radio Podcast
"boston university" Discussed on Boston Public Radio Podcast
"Professor emeritus of international relations and history at boston university and his new book which we should all go out and read is after the apocalypse. America's role in a world transformed. Thanks so much to andrew base for being with us coming up representative. Mike conway joins us to talk about his legislative. Push to reverse a states. Happy hour ban ki on eighty nine seven. Gbh boston the radio. Michael boston public radio mar dragon. Jim brady massachusetts band happy.
The Garden Rebel
2 Boston Trains Collide, Sending 23 to the Hospital, Authorities Say
"In Boston into the cause of a collision between two trolleys Friday evening, Massachusetts Bay Transportation Authority general manager Steve Puff Tak told reporters. Two trains headed West found on the B branch of the Green Line and the trailing train collided with the train in front of it. It happened around six o'clock last night near Boston University. 23 people were taken to hospitals, but none of the injuries were reported to be life threatening. This is
Dennis Prager Podcasts
Our New Post-racial Myth
"So it's all laid out in this piece in the atlantic which constantly publishes left-wing pieces that have a veneer of intellectuality that that is the way i would define the atlantic the new york times Opinion writers are are more street fighters. The atlantic has this patina of intellectuality. So the abram x. can be pieces worth analyzing. He is their foremost spokesman for america being a racist society so this article just published is their way of explaining it and it sounds very effective to his students. I am sure at boston university and tool your kids who go. Oh my god black baby style twice the rate of white babies that proves that there's racism in america. We don't care about black babies dying. No evidence ncis is given for how exactly. Racism produces this a fifth of native americans. And latino americans are medically uninsured. Does he include illegal. Immigrants in the latino americans. What if he does. Do you think it's an honest. Condemnation of the united states almost triple the rate of white americans in asian-americans native people see he switches when he can't find the data for blacks so he goes to native americans
"boston university" Discussed on Radio Boston
"Was thinking about going up for tenure in a in a senior white. Our colleague of mine wanted to sit me down and basically was was against me going up for tenure but then stated well you would probably get tenure because you're a minority and i had already published more than that faculty member had when they went up for tenure and so it just. It was striking to me that she would say that. Over the last year you have spoken a lot of truth to power when we use that phrase. The prophetic voice seems to me. You've set out to be prophetic voice. And as you mentioned at the beginning of our conversation that is not without taking a lot of criticism and often from people who haven't delved deeply with you into the subject matter that you're talking about a year later how has that been for you are you are you. Are you warn. Are you energized. Are you ready for the next year. Do you need a break. How are you after. A year of this was certainly has been a year and i think that i've tried to reassert. Reassert my faith in readers. And what i mean by that. Is you know if a critic who hasn't read my work or who just blatantly distorts my work in order to to argue against me or to frame in some way does that. I have to trust readers that the readers who read my work and read it closely will know that. That's actually not what i'm saying or doing and that that will actually discredit the critic. Rather than me. i've just tried to lean on readers. Entrust readers in all we can do is right An entrust readers to to read an an an and really grasp. What we're trying to say. Is there a fair piece of criticism you've received over the last year. That's that's developed you further. I think as i could write stamford the beginning or even have been anti-racist.
"boston university" Discussed on Radio Boston
"Two five five. We have ernie on the line. In quincy ernie go ahead. Yeah hi can you hear me yes. We can't ernie yeah thanks So you know my my flex. I remember a year. I guess exactly though and and welcomed the boston It they'd be thinking about when i was eight newspaper reporter. I applied for job at the globe. And i've been a reporter And i was nearing the end of the process and thought it would be hired was sold there. At that time i was. I was the wrong race. Which white and the wrong ethnicity. Which is irish and the globe had had a very long run of that. And you know my. My interpretation of that was honestly. I was grateful. Because i felt like we've had a long run. It's time for all of us to kind of step aside and and and kind of applaud the promotion of people of color also qualified to do this job. And i've never felt differently and i've i've told this story to many people over the years they said well. You must've been like angry. I i was not angry. I felt like it's time and this is over thirty years ago. There was still struggling with this and that to me is disappointing. Thanks for the call. Ernie professor candy. Well i mean obviously. I can't sort of comment specifically on. What would happen that story. But but but i do know that when an organization decides to hire a candidate of color over qualified over a white candidate that's qualified that typically white candidates don't have the same reaction that that ernie did and assume that that candidate of color is not qualified which then presupposes that people of color and are qualified Which presupposes that people of color only get positions because of their skin color And and that then only creates more division. It makes me think of the story. That's unfolding right now regarding espn. Rachel nichols a white woman. Longtime reporter anchor for the network was caught on tape making some disparaging remarks about maria taylor..
"boston university" Discussed on Radio Boston
"This idea of solidarity which came up and we'll talk about some other podcast episodes as well but there was so much in this idea of zero sum that seemed to get at the heart of anti-racist work you talk about solidarity It really resonated with me and doing anti-poverty poverty work people often argue that we deprive ourselves when we hold others back from being their full selves. I think of mona lisa smith and mothers for justice inequality in boston talking about you know. Every child is our child A year ago. When you and i talked i i asked you about policies that may be needed to be in place in boston. And you rightly said. At the time i just got here. Gimme a second. But it's it's been a year now. Are there policies especially policies towards poverty or children in boston that you think we need to see or reverse in order to become a more anti-racists city so few years ago a young one of the youngest mayors in the country but enabled michael tops Was mayor of stockton california and he decided to to to inaugurate a basic income program which he would provide a basic basically checks to to local people to particularly impoverished people and then study what type of effect it has on their lives study even what type of effect how they used the my and in that program that he started in stockton his spread around to other cities. And why can't we have a pilot basic income program in boston. The original study found that people do what other people would do it when they get extra money. They pay bills. They go back to school. They do things that that allow them to become more more productive. This thought that low income people are going to quote by sneakers a waste away. Money has never really been proven by science and by providing funds for people it lifts them out of poverty and so so you know poverty and in the city is disproportionately my understanding black and brown until it could. It's something that could lift sort of people out of poverty. We did have The town administrator in in chelsea after they did a pilot of guaranteed basic income program and the evaluation of it found that it was targeted towards hunger. In that people spent the majority of people spent the money for some foremost on food to underscore what you're saying. Are you ready to go to the phones. Are you ready to take a call..
"boston university" Discussed on Radio Boston
"You can't say something bad or good about a text that you haven't read but but obviously that's that's something that that that's done and So i've tried to figure out to learn how to respond to that. And i've learned to just not respond at all. I wanna think about this idea of the long step in there. Such a visual in that. And i'm also thinking about the conversation that you had with heather mcghee on your podcast where you talked about this zero sum framing and i wonder is there something that one has to be willing to lose or to give up in order to take that long step from learning to action. Well i i think at a personal level if it is it is. It is difficult for some people to admit that even though that the nation is is not a meritocracy and the reason why it's difficult for some of us to admit that because then that means that we are not in our position purely off of merit and and and and and it's hard for people to to to know into this admit that and And that indeed as me as a man that that. I've had an certainly benefited from from male privilege or even sister underprivileged or or. You know the fact that. I'm heterosexual a heads forms of privilege. That certainly have benefited me along the way and i know it's hard for people to to admit that because then they have to give up is idea that they are self made and everything that they've accomplished has been because they're so great and because they're so work. I i want to stay with that for a minute. And with this conversation that you had with author and activist other mcgee. She wrote the so the about the so-called zero-sum game your conversation made me think about a chapter in the book the warmth of other suns by isabel wilkerson. It also made me think of richard reeves's work on dream hoarding. It's this idea that we buy into that allowing someone else to rise means losing our own relative position. I i wanna play a little bit of the sound of you and mcgee talking about it using a really accessible metaphor which is flying here. it is in a way. Their child's school is almost like a first class school. They're like whoa. If we create equity than i'm going to be back and coach. Yeah i don't want that. I'm gonna lose my kid's gonna lose but it seems to me that white americans should be assessing themselves from other white people in the west. Yeah and when they make that comparison that's when they can see actually what they don't have how they're in coach right and in fact maybe and other societies in the western world. Everybody's just in last. There's no little that the flight attendant moves over right. Everyone gets food right. Everyone has a leg room. You know everybody gets to bring a bag. I wanted to ask after i heard that. Do you think there are places where everyone is in first class. Have we been able to overcome that kind of if i get mine. You can't have yours. And if you get yours than i can't have mine any more dynamic anywhere in the united states and and i think that i think that's what's sad In in the sense that.
"boston university" Discussed on Radio Boston
"Welcome back in command and as we start this conversation. I should note right at the top for full transparency. That boston university holds the broadcast license for us here at wbz. You are so. I was thinking this morning professor candy. The first time i spoke with you was exactly one year ago today here on radio boston. You were moving to boston to start the center You and i have talked a couple of times since then here on the show at another event. And we're always asking you to teach an a year into this. I wonder if i can start by asking you some of what you've learned. I wonder has it. Been a journey for you. And what have you learned in the last year. I've learned so much. Because i read so much instead he'd so much but You know a few major things would highlight is that the step from awareness to to action is a is a is an extremely long stepped and i think we as a nation are still trying to take that step in which is a a governing. Majority of americans aware of racism. Aware that it's a big problem. But but we haven't had the ability to to really take those major steps towards towards action toward ridding this nation of this proper. You only pause because you said. I think he said there were three things. I wonder if there if you want to stay on that one for a while or do you want to sort of elaborate. The three and then we'll talk. What's better for you Will i think secondly i. I've learned the way in. Which i i've had to figure out how personally to to respond to People who are criticizing my work web read my work and that's been very difficult for me because i'm just used to. People criticized a brit like as a scholar like or even as a teacher. You might classroom is not the united states so you know i know in my classroom..
Marketplace with Kai Ryssdal
Why Black Entrepreneurship Surged During the Pandemic
"Is of course the one year anniversary of the murder of floyd in a year of protests and reckoning there have been signs of hope even during a pandemic that hit black americans particularly hard and closed many black owned businesses new data suggests that people in black communities started new businesses over the last year in cities like new york and atlanta the study from the national bureau of economic research says. Black americans were more likely than white americans to take steps toward entrepreneurship. during the pandemic marketplace's euler has more on. Why so the study found that. After a relief package is passed last year. There was a big surge in registered business formations in the following weeks. Catherine facia teaches business at boston university and helped write the study. She says that's despite the cares. Act not directly infusing. Any money into new businesses are passed not to pat is a lot of start up formation so it was very interesting for us to see that cares out had that ripple of fat another reason for the surgeon. Black entrepreneurship could be the americans. Now have a better understanding of historic inequality or he goes. Mom is an assistant professor of management at columbia university and a co author of the study. There's being clear intends in banks and government to make sure all the financial reports out this year. Which is wachner hurts. And andre perry says that speaks to a bigger lesson to be learned from this study about access to capital. He's a senior fellow at the brookings institution. If you really want to see the economy grow figure out two ways to invest in the under appreciated assets in our community in that happens to be black and brown communities it happens to be black and brown entrepreneurs he says black people represent about fourteen percent of the population in the us but only two percent of all businesses with more than one employee this investment and black businesses. He says shouldn't be a pandemic induced
News Radio 920 AM
"boston university" Discussed on News Radio 920 AM
"We weren't like China where they were corrupt royal regimes. Don't corrupt monarchs know or or attempts at like a Democratic republic. No Marxism has to convince you that the system you're under right now. Is is bad and you need to replace it so they couldn't do it economically. Because everybody said, What are you talking about? Look at how people live in Russia and China. Forget about it so they can't do it economically. They did want to try to do it over race. In the past. What the United States did things like the civil rights movement. And all that, but But Now. You can't say. Well, you don't have civil rights legislation. You have this oppressive government Now you have to go after. Okay. You were founded on a lie. And you were founded on the backs of slaves. And this is what we have to do to rectify that revolution. I mean, it's it's It's so true. Think about some of the stuff. That is being proposed. Abram Candy ever heard that name? Um At Boston University, directs the center for anti Racist Research of Boston University. This is what you learn when you start digging deep into critical race theory. Well, Abram Candy wants to create a department of anti racism. So you know we have Department of Defense. Apartment of the Treasury Department of Justice. You know, we have all of those department know that that makes up the cabinet in the executive but hold on. Candy wants the Department of Racism. But waiting here this The Department of Racism. Answers to No. One. About themselves, and their goal is to go through the government and go through society and if they deem something racist to get rid of it. There's no like a new election to overturn that decision. There's no balance of power with the legislative and the judicial note. That's the kind of stuff that's coming out of this. Is. Racism is so evil folks, It's It's playing us. I know it sounds like with Jim. What are you getting crazy with the red scare? No, No, I'm just trying to tell you exactly what critical race. There he is. And it's not what you think. And why do you think they're pouring it down? Kids throats in schools? Force feeding them. Like a like a goose and frog wa Why do you think they're doing that? Air polluting little minds that will grow up to be big minds. 855403 98 46..
Olympia Dukakis, Oscar-Winning ‘Moonstruck’ Actress, Dies at 89
"Winning actress Olympia Dukakis has died at the age of 89. She was born in law and went to Boston University. She also was the cousin of former Massachusetts governor Michael Dukakis when she accepted her Academy Award in 1988 for best supporting actress for the movie Moonstruck. Caucus gave a shout out to her cousin who was running for president that year to my friends and colleagues in New York and the whole theater. Thank you very much. Okay, Michael, let's go. Olympia Dukakis was one of the BU theater graduates who started the Charles Playhouse in Boston in the late 19 fifties.
The Nutrition Diva's Quick and Dirty Tips for Eating Well and Feeling Fabulous
What the Heck Is Seitan? Is It Healthy?
"My editor. Who is way cooler than me has been hanging out on tiktok lately. And she says she's seen lots and lots of videos about cooking with satan. Apparently this meat substitute is having a bit of a moment. But i think there are still plenty of people who are still unfamiliar with this ingredient. And what the heck is it. How does it stack up nutritionally. And how do you eat it. Satan spelled s. e. I. t. a. n. is not a new thing. The word is japanese and it was coined about fifty years ago by one of the proponents of the macrobiotic diet. But the food that it refers to has been a staple in asian cultures for at least fifteen centuries. I remember seeing it but not buying it at the food cop that i belong to as an undergraduate at boston university now. That wasn't quite fifteen centuries ago but it was still long before the days of whole foods stores and yoga studios on every corner back then food co-ops and health food in general occupied sort of a fringe culture leftover from the age of aquarius. Today of course it's another story. Plant based in plant. Forward diets have become relatively mainstream. And you're much more likely to run across satan at your local grocery store. It's often next to the tofu or the plant based meat alternatives. If your local grocery doesn't carry it you might need to seek out a health food store a food co-op and yes. They still exist or an asian grocer. You can even make your own and have more about that in just a minute. Is most frequently used as a meat substitute in vegetarian diets. It has sort of a stringy chewy texture that makes it a fairly good substitute for meat. Unlike some meat substitutes however it's a decent source of protein but the source of the protein may surprise you because satan is made from wheat gluten.
The Nutrition Diva's Quick and Dirty Tips for Eating Well and Feeling Fabulous
What the Heck is Seitan?
"My editor. Who is way cooler than me has been hanging out on tiktok lately. And she says she's seen lots and lots of videos about cooking with satan. Apparently this meat substitute is having a bit of a moment. But i think there are still plenty of people who are still unfamiliar with this ingredient. And what the heck is it. How does it stack up nutritionally. And how do you eat it. Satan spelled s. e. I. t. a. n. is not a new thing. The word is japanese and it was coined about fifty years ago by one of the proponents of the macrobiotic diet. But the food that it refers to has been a staple in asian cultures for at least fifteen centuries. I remember seeing it but not buying it at the food cop that i belong to as an undergraduate at boston university now. That wasn't quite fifteen centuries ago but it was still long before the days of whole foods stores and yoga studios on every corner back then food co-ops and health food in general occupied sort of a fringe culture leftover from the age of aquarius. Today of course it's another story. Plant based in plant. Forward diets have become relatively mainstream. And you're much more likely to run across satan at your local grocery store. It's often next to the tofu or the plant based meat alternatives. If your local grocery doesn't carry it you might need to seek out a health food store a food co-op and yes. They still exist or an asian grocer. You can even make your own and have more about that in just a minute. Is most frequently used as a meat substitute in vegetarian diets. It has sort of a stringy chewy texture that makes it a fairly good substitute for meat. Unlike some meat substitutes however it's a decent source of protein but the source of the protein may surprise you because satan is made from wheat
"boston university" Discussed on Cardionerds
"You for joining us. Thanks so much for having us. This is awesome. Thank you now. I'd like to introduce our acp. Our speaker dr kerry schafer who is an attending in the department of cardiology at children's hospital at brigham and women's hospital and at boston medical center. Dr schaffer is an adult congenital. Heart disease specialists who loves to take talents all across the city of boston and is the perfect person to offer an easy. Pr perspective on this fantastic case. So thanks dr schaffer. We look forward to hear your thoughts. Hi this is keri schaefer. I'm an adult congenital cardiologist. And i'll be discussing this very interesting please. That we've heard about today so in seventy eight year old woman. With the sinus minnows defect partial in almost pulmonary. Venus return and coronary artery disease. We really have a lot of physiology to think through one of the critical parts. When we integrate such complex physiology is to really understand each individual component. Well so that we can kind of identify which parts are related to each abnormality for that reason. I'd like to focus a little bit just on the sinus. The knows steve. Act and the partial anomalous pulmonary venus return and as we go through this physiology. I just want to remind all of the listeners out there that when you do. Ach physiology really have the opportunity. To kind of apply the knowledge you have for medical school about just truth. Physiology to the human heart can't make assumptions as we sometimes do in the setting of normal cardiac anatomy and so we really need to think about exactly what are the compliances of the downstream structures and whereas the blood flow. Okay so let's start off with this patient's issues so she has a sinus venosa defects with partial anomalous pulmonary vein so first. Let's talk about sinus. Venus sixty x so sinuses defects happen about five percents of the atrial level defects. Many of you might have heard of atrial septa defects as being part of this family. I think we as cardiologists really need to refine that definition and remind ourselves that the defect. We're talking about today. The sinus defect actually isn't in the true atrial. septum atrial septum defects are really just. The ostiense accused him in austin primum defects that we see much more commonly sinus knows. Defect is actually a defect as the pulmonary vein. The typically right upper pulmonary vein runs behind this superior vena cava and it's the lack of that wall that results in this defect the shunt physiology is quite similar to asd's and so i think physiologically kind of both them all together. When we think about a sinus analysis defect when i see a patient with an with a sinuses defect the first thing. I do is really get a lay of the land in terms of anatomy. One of the most important associations is what we've talked about today. This partial anomalous pulmonary venus return and typically the vein drains into the sbc near the sinus defect however. It isn't entirely uncommon for patients to have another anomalous pulmonary veins and so as we think through cases like our patient today. We want to be sure that we do an anatomy scan including the assessment of the. Sv see up to the level of the anonymity because on occasion there can be higher pulmonary vein anomaly and that will radically change our strategy for repair so after we get through assessing all of our anatomy we wanna make the next step in to determining what is the effect of the shunt and there's really two main ways to look at the effects of the shunt the first way which is nicely outlined in our case is to look at the cardiac physiology on imaging so typically we start with trans theoretic echo and we look at what the size of the right atrium and right ventricle and this is an important part in which we think about where the shunt goes so. Let's just pause for a second in think about this blood flow as it goes through the shunted area so if we have a sinus noces defect but we really have is a defect right. Where the right upper pulmonary vein would be. Coming into the left atrium. That wall is missing. And so what can happen. Is that left. Atrial blood goes into the right atrium. Really very very superior -ly near the sbc so the Go left atrium right atrium right ventricle pulmonary artery pulmonary vein and then back to the left atrium again to make that shunted cardiac output so then we look for the effects of shunting. We wanna look at all those structures. Do we see right atrial. Dilation do we see right ventricular dilation. Do we see pulmonary vein. Dilation in pulmonary artery dilation and in this case we saw all of those things. And i think it's it's especially important to think through the effects of that volume loading of these chambers so our patient had significant tricuspid regurgitation. At least in part due to the fact that the right ventricle was dilated and dust. The tricuspid in euless. We can also think about the fact that she has atrial fibrillation now. Certainly there is definitely plenty of reason for a seventy eight year old woman with a history of heart failure with preserved ejection fraction in coronary artery disease to have pulmonary vein dilation but even patients who are younger than this patient who only have a partial in almost pulmonary vein and scientists noces defect. They also can have a fifth in the reason the same as every other patient. That when you how this shunted blood that goes through the pulmonary vein that dilates the pulmonary vein indus- puts the patient at risk very so she really had plenty of reasons. Not just the standard ones to have adrian relation so after we get through assessing the anatomy and we get through assessing the effect of shunting on imaging. The next thing we typically do is assess the effect of shunting on the human of this patient. And that's really where we make our final decision in terms of our next steps and in this case we talked about the fact. This patient had a significant left to right shunt. We don't discuss a ton about the possibility of a bidirectional shelton. I think that's appropriate because there's going to be plenty of reason for a patient like this with la hypertension to have a left to right shunt and when we do the shunt calculations we find that. There's probably shunt fraction of about two point. Five to marie depending on how we make our calculations and what that means essentially is that. There's two and a half to three times as much blood going through the lungs and the pulmonary veins and the right ventricle. Dan the normal amount of cardiac output going out of the left ventricle. And a wardha. When we think about that we have to remind ourselves that the pulmonary vascular resistance is going to be calculated based on the flow through it and we might remind ourselves of the law which is how we calculate all pulmonary vascular resistances where the resistance is the change in pressure over the flow. So in this case we would use the trans pulmonary gradient and we would divide it by the q p so.
"boston university" Discussed on Cardionerds
"What is presumed to be group to pulmonary hypertension who presented to the hospital with recurrent disney onyx or shan notably. She's had multiple admissions in the past year for was ultimately diagnosed with heart failure with only really mild interval improvement in her symptoms. Each time this time she again complains of dismay that was worsened over a period of several days and at the time presentation she really denied worth. Thought mia perks. Zeman nocturnal dismissed or cough. She had not noticed significant change in her appetite and didn't really have significant abdominal or extremity. Swelling she did reports on exerts lightheadedness. Though she had not had be she also describes him exertion chest pain that was sharp nature. Alex thanks history. We so often take care of patients with heart failure and admissions compensation that it's almost hard to zoom back out and think about their overall trajectory right. But when i hear a patient who has hartfield in his head multiple admissions over the course of the year that pretends very bad prognosis over all right so my level of concern is already pretty high this particular admission when she's denying the usual review systems for fluid overload or thought me up. Pnd i m curious what this particular. Admission is about regardless. It'd be helpful to know more about the context of this presentation like her overall the rest of her medical history. Just c-can start identifying the reasons why she's having so many presentations. What else do we know about her for. Sure i think the social and medical history context is super important in this case in terms of her social history. She had recently emigrated to boston to live with her daughter. From haiti as she did not drink any alcohol smoke. Tobacco use any illicit drugs. Her family history. She really didn't know what time She had no known allergies and in terms of her medications. You really was not on a time. She was on looting. Hypertension and then froze might forty milligrams. Vip for her heart. Failure begs alex. I think one thing to highlight is that she really did not get much medical care in haiti and she had been having kind of disney a- and symptoms similar to this for several years. And so it's kind of unclear as we'll see as the case involves how much medical care in the past. She'd received but she did not remember really being worked up for this in any meaningful way. Prior to moving to the boston area exactly So moving onto some objective data from her initial presentation. Vials are notable for a hurry. That range from seventy two to eighty nine. She had a blood pressure on thirty over seventy in her. Auctions duration was ninety five percent on room air on physical exam. She was a learn ranted times three. She was in no obvious distress in speaking dress. In full sentences cardiac exam was remarkable for irregularly irregular rhythm a normal s one in a fix let s to she had an elevated jvp to twelve centimeters of water. Her lungs were clear to osco tation bilaterally. She had some mild diffuse abdominal tenderness but did not appear are distended and then she had traced long extremity edina so alex i was a great description of this patient's presentation and it's it's not an uncommon presentation that we see and we say that frequently on the cardio nurse case reports on the podcast in general that these patients present sometimes quite similarly but the key is trying to differentiate those small little tidbits from the history of the small tidbits from the exam that can of differentiate the next steps. So i'm trying to start thinking through if putting in buckets the large bucket. The symptom is dyslexia. And it's in someone. That's older and the carries a diagnosis of half half and a lot of times when we get that half path diagnosis. It ends there for a lot of clinicians. We fail to ask why. And we know. And we're learning from people like sanjiv shop and dr sherma at hopkins and across the country. That have half has so many different types and then we really have to near down in what we're talking about when we speak about half half so one of the first things that i'm thinking about here is. What is this diagnosis right. It's a chart bagnis as far as we know at this time right. But is it truly a diagnosis. Where the patient. One of the things that sometimes helpful is the half half score. And we put a link to that in the show notes and that can be distinguisher. What's the likelihood they have some of the markers of that. Are they heavier. The hypertensive afib history and echo parameters of filling pressures and. This patient certainly has a higher half half score and just clinically. This is someone that fits that phenotype right afesip is. Hypertensive is older. So certainly we're thinking about that but they're also factors. That doesn't quite fit for me. this is someone you're describing with a bmi around twenty eight someone that isn't grossly volume overloaded so striking to me. Is there something else going on. And what could be. The ideology of the patients have path on my thinking. When i start to hear it think about. Could this be an amyloid diagnosis on my exam. I'm gonna be really paying attention for clues that may be fitting to that. Ought autonomic rathi or the multi organ involvement as their suggestion of Pat omega lee or dysfunction on the lives could this be a patient that has a another restrictive cardiomyopathy the prominent right sided symptoms. So we're not going to delve into the full differential of what can be half path but the key question is always asking. Why and i think you guys are setting that up nicely of what could be going on. And is it just have path is that phenotype that we're all so familiar with or is there something else that's brewing here. That's actually right. Garon especially when patients come back with recurrent hospitalizations. I think it's always important to revisit every time and always think about. Do we have the right diagnosis for this patient. This time so her labs are notable for a cbc with a white count of four point. Five human trump point one in platelets of one fifty six. Her bmp was notable for gratton in of one point. Four eight with the un of thirty five was elevated at point two three and subsequently up trended slightly two point two four three her. Bnp was eight hundred eleven and it had been about five hundred to eight hundred on her. Prior admissions her chest x ray demonstrated cardio magli pulmonary vascular enlargement with no consolidations or fusions ekg demonstrated fibrillation with right axis deviation in an incomplete. Right bundle branch block her. Most recent echo had been one month prior this demonstrated normal. Cavities is wall thickness at the upper limit of normal injection fraction of fifty five percent. Interestingly she had a severely dilated. Rv with reduce global systolic function with a taxi of one s prime of flattening of the septum in both sicily. And i asked. She had severe by a drill marchmont. There was also severe. Tr and her pony artery systolic pressure was estimated at fifty nine millimeters mercury. So this really kind of piques. My interests and i'm kind of honing in on some of the exam findings as well as what you just talked about on echo alex when i mentioned a severely dilated and similarly dysfunctional right ventricle. I think that in the context of split as to on exam really makes me suspicious for initial central defect. Which i think we all probably remember from step one being highly associated with an ast the asked can cause longstanding rv volume overload lead to profound right-sided failure symptoms leading to this patient's presentation. Now we didn't note an inter atrial shunt on the t. t. e. But that means we may have to look further. Go hunting and rb failure. You know the right ventricle can sometimes be considered the forgotten ventricle. But it's really a huge mistake. Discount this half of the pump because so many patients can present with isolated right ventricular failure and have life limiting symptoms and have a very high mortality especially in the setting of heff path. Rv failure and try casper regurgitation when thinking about rv failure. I find it helpful to break down the causes in two buckets specifically volume overload pressure overload or primary cardiomyopathy processes and so some of the volume overload issues that lead to right ventricular failure include valvular disease like tricuspid regurgitation or insufficiency as well as intra cardiac shunts like atrial central defects. And then some of the biaggi's right heart failure that fall into the pressure overload. Category include things like pulmonary. Embolism or chronic thromboembolic pulmonary hypertension pulmonary hypertension from other ideologies or severe. Lv failure leading to elevated right sided pressures. That also goes along. With mitral valve disease have path anything that can elevate pressures on the left side can lead to pressure overload on the right side and then things like chronic hypoc see mia and onyx to know sis that also lead to elevated pressures for the right ventricle. The see i meant things that lead to cardiomyopathy is causes right. Ventricular failure are cardiomyopathy area. C current mentioned previously amyloid and things like right ventricular septic cardiomyopathy post transplant. Rv dysfunction just kinda round card in my pathak diagnosis. So right now. Based on our patients presentation. I'm kind of leaning into more the volume overload ideology for her right ventricular dysfunction. But this is kind of super super interesting. I can't wait to see more diagnostics. That may lead us to specific geology. So they need. That was truly a fantastic description of what your thought process of going through here in this cases interpreting the exam findings in the echo findings. And i wholeheartedly agree with some of the things you mentioned on your differential and also thinking about what's going on is this rv volume overload rv pressure overload. What's going on the left side. And i'm still trying to reconcile in my own. Mind what this patient has been diagnosed with in the past and what they're presenting right now this diagnosis of half path. And then what. We're seeing a least on exam and echo predominantly right side symptoms. And so some of the things that i'm trying to figure out is danny. Alexey both mentioned at this. Point is what's the contribution to each side of the heart of these patients symptoms. How much is the lv contributing. How much is the left. Atrium contribute which is critical aspect of thinking through half path. Sanjiv will say when we think of raff. It's an issue of lv failure when we're thinking about half path it's a issue of atrial failure and then thinking again. What combination of these factors is. What's leading to the patient's symptoms so to me what you've described so far is a patient has some evidence. Potentially of lv stiffness or essentially a disease or cardia. My empathic process there. You're describing some wall thickness at the upper limit of normal ejection. Fraction approaching borderline area's predominantly a patient. That has rv dysfunction. So is this isolated p. h. Is this a combination of pre and post capillary. Ph or is this predominantly. Lv and one of the things that sometimes it's helpful especially for me not just on the symptoms which we've discovered on previous episodes including predominantly right side. Symptoms like pat omega aside as lower. Extremity dima isn't as an echo finding paying attention to some of the diastolic and eat at a can be a marker of predominantly. Lv verses rv involvement in our listeners. That are still training and not in cardiology. The a meaning. What the inflow across the mitral valve is the velocity of it and early and late diagnostically and impatience with predominantly. Rv dysfunction that ebay is less than one and the reason is that there's tends to be increased resistance across the pulmonary vascular meaning that there's reduced filling of the lv and it tends to occur later. So when i see a patient characterized with half path. And then they have a either a less than one. then i'm starting to think well Is this really an. Lv issue or is this predominantly rv issue and what's leading to that rv issue. Now it's a crude marker but it's one of the things that's helpful to me so as we begin to think that a differential one of the big buckets that i'm thinking about here is this isolated v. combination of lv. Rv are predominately rv. And that's going to help me break down difference further almond any other thoughts. You wanted yucca. And that was beautiful. And i think the question you asked is sort of existential one. But it's so important when you say what is half path and we're still trying to figure that out but it's not just heart failure in the lv f. is preserved. Right i mean if you have heart failure because you have mitral valve quarter rupture in so now. You're in acute heart failure. It's not that you had sought dysfunction in the lv right and so two categorized Who would do the patient of service right insult in this context by looking at the echo that alex beautifully outlined for us. It's really the right side that suffering great. I mean you've got the right side. It's our dilated. The septum is flattening and blowing into the left side. Both during sicily indicating rv pressure overload diaster indicating volume overload. And then i think okay is the lv. Just an innocent bystander. Here right i mean. It's just trying to do his job. And so i go back to danny's categorization of how he approaches rights had heart failure. Nothing is this volume overload and we certainly have a suspicion for volume overload dystopic simple flattening and that may be presumably from the severe. T are now. We didn't hear anything in the equerry to suggest. A primary tricuspid valve pathology if you recall from our last few episodes from carcenoid valvular heart disease with severe tr. But here it may just be functional tr. So is there rv pressure overload predominantly from says the pulmonary hypertension and here we do have an elevated vs sp which in the context of severity are may actually under call. Maybe the pulmonary hypertension is worse than it actually is. There is systolic central flattening indicating pressure overload. Right in. if that's the case the question is why is it that the patient may have pulmonary hypertension right so at this point in the case. I'm really excited to dive into the next phase of diagnostics. Right in one of my favorite things about cardiology is to use all with multi modality diagnostics to identify lesion. So here i'm thinking. Okay danny outpointed out fixed but as to is there a shunt at a level that we can see in a trance theoretic echocardiogram. You may consider getting a trans office. Echocardiogram cross sectional imaging and then also further. Interrogate the cause of pulmonary hypertension. Right heart. cath could potentially be useful especially with with oxygen. Saturation is to calculate a shunt fraction to both diagnosed plumbing. Hypertension consider the causes pulmonary hypertension. Whether or not. It's left cited as well as interrogate for a possible shunt. So what was the next step here. We've got a number of questions resulting in to the fact that this patient probably has a picture that's more complicated than just have pets alone. What did you do next to figure it out. Absolutely i'll also echo karan's point about what is the contribution from the left side. What is the contribution from the right side. I think when we saw this patient in heart failure consultation we were really struck actually by her lack of left sided symptoms. And so we were also really thinking about. Why does she have such profound rights and rights dysfunction on her echo absolutely so back to our case. The patient initially had been restarted on her frozen night. Infusion at the prior effective diuretic dose and after about a day or so of attempted diary says cranny began to rise in her symptoms were really unchanged and at that time. Actually the team. That was taking care of her. Pursued a cd pulmonary angiogram. Due to the persistent dismissing really kind of limited signs of crime overload. The exam showed no evidence of pe but did show in anomalous insertion of the right superior pulmonary vein into the sbc this partial Venus return was a super interesting finding especially in light of her. Rv dysfunction and really helps the blow it off this case. So partial anomalous pulmonary venous. Return is a rare congenital. Finding and knowing about the associated congenital lesions can be super helpful. In clinical practice re flee harshly novelist pulmonary venous return or pa. Vr exists when one or more but not all of the primary veins return blood from the lungs to stomach venus system. It's actually very commonly associated with scientists minosos defect. There's also a variant called scimitar syndrome. That exists when part of our all of the right long has drained anomalous into the ib see it gets its name from appearance on chest x ray given the appearance of you gusta scimitar in ancient sword. Our patient didn't have that. But i still think it's a really great name. So based on this we're thinking about what study we could do next. So alex i just want to clarify. When we partial anomalous pulmonary venous return essentially anatomy. You've got four major pulmonary veins that are draining. Oxygenated blood into the left atrium in this case won the pulmonary veins right upper pommery vein instead of training onto left side. It's training to the right side of the level of the spca and so essentially functionally. This is a left right. Shut and could help explai- some of the findings. In this case. I agree with the blows. The lid off the case here. I know about what what we're gonna do next diagnostic imaging and going back through the patient's history and so forth. But as you mentioned. I think there's still a couple of things here left to explain right and tell me if i'm thinking through this right alex danny but a partial anomalous henry munis return is a is a volume issue and the question is what we saw on. Echo was definitely evidence of diastolic sept flattening. Which would be indicative of volume of lord of the rb. Well we still have to explain the pressure overload. So the question is is this from longstanding anomalous pulmonary vein return or is there something else that's contributing to it. That's a great point koran. And i think that this comes up all the time when left to read schanzer found and as you diluted too long standing left to right shunts can cause volume load to the right ventricle and eventually cause pulmonary hypertension from that longstanding volume overload leading to elevated pressures in the right side circulation and can oftentimes lead to this both volume and pressure phenomenon that we see in this patients and as you had said. I don't think we've necessarily performed all the necessary cardiac diagnostics and even in the setting of partial anomalous pulmonary venus return. It's highly associated with sinus. Vanessa's were to talk about but are a form of st. That is not necessarily seen on super well so as you'd mentioned there's a lot of other diagnostics that we still have yet to do. And so the team. In this case proceeded after they found this partial anomalous pulmonary venous return. They sent the patient for transit. Safa jill echocardiogram which did in fact identify science knows minosos defect with a left to right shuts and so that kind of additional left to read shunts was probably the reality. For long standing right ventricular pressure volume overload. So i wanted to talk a bit about sinus. Vanessa's because we hear about these and we know that they're not well seen on t. e. but it can sometimes be a blackbox people in that they don't really know. Exactly what the senate knows. This is what a senator minosos defect can present like. So not as mrs defect accounts for ten to fifteen percent of all these and is commonly seen in association with an anomalous pulmonary vein often superior. Sinus defect goes along. With a right upper partial anomalous pulmonary venous return an inferior sinus. Vanessa's defect goes with right. Inferior partial anomalous pulmonary venous return and one big takeaway should be that in cases of right. Heart enlargement were an. Ast is not readily visualized on t. e. a. t. e. or a cardiac. Mri can be extremely helpful. Diagnostic tools to assess for sinus analysis or coronary sinus defects. Which often sit in a place. That's not readily visualized from the trans-pacific thoracic imaging modality danny. That was such a great explanation and thinking about the sinus vanessa's defects along with a partial anomalous public. Venus return to essentially have left right shunting at two levels whether it's a superior centers Effect but i'm just kind of thinking about all the different types of ast needs whether it's awesome premium rostrums dome scientists noses etc. What is the sinus of enosis structure. You're talking about. Can you take me through that a little bit absolutely so. Let's roll back the clock and put back on our embryology hats and pretend were sitting in the primitive atrium so in the beginning the primitive adria are one chamber and the science knows is entry way for multiple primitive venus structures to drain. Blood into this single atrium. So the sinus been assist sits behind this primitive dream between the two developing vena cava an early on the primitive venus structures including the common cardinal veins the fiddling veins and the umbilical vans all drained through the says into this atrium and then into the primitive ventricles so slowly as heart develops hemodialysis shifts. Forced this sinus venosa towards the right specifically three major things happen number one. These anterior cardinal veins anastomosis to become the internal jugular veins and sbc and this naturally drains more towards the right side of the sinus fenosa polling blood and pulling pressures towards the right. The second thing that happens is the left umbilical and villain veins degenerates which directs blood towards the right side of the sinus thrombosis again and third. The right umbilical vein. Degenerates with more blood. Coming through the right villain vein from the caudal portion of the developing fetus. Now these he dynamic shifts in this primitive sinus von assists and primitive single atrium shift blood towards the right side of the sinus. And this leads to degeneration of the left side of the sinus. Vanessa's which then becomes the coronary sinus. And the oblique vein of the left failure of the left side of the sinus fano. Cystic completely degenerate can leave a little tunnel or a little israel. Central defect between the left atrium. And the right atrium. Then in adults the sinus vigneault says becomes the smooth poster wall of the right atrium or what is called the sinus venire and adults and this is separated from the rest of the atrial wall by the crista term analysis. Danny you outline the steps within the embryology so beautifully. I just have to say he had to take a moment to appreciate you. Not just how amazing this whole processes in how incredible it is that we don't see defects more often. Miami's just fascinating at. It's so true. It is remarkable heart twists and folds turns and degenerates. It's a true miracle it really is but yeah let's let's go back to your case which you do next. So we've identified an anonymous right superior pulmonary vein and a science knows this effect but as you kind of alluded to before the next step is really to quantify the shunts assess for complementing pulmonary hypertension and kind of get in there and measure some pressures volumes and some oxygen saturation. So she proceeded to the table of truth. The catholic taylor to define the extent of the shots. At possible sequentially stewart. Take us through the right heart. Cath absolutely danny. Let's start with her. Initial pressure measurements. So i like this sort of imagine myself walking through the heart and of magic school bus style. So let's go. We start in. The ra were patients are a pressure was twenty one as a reminder normal being less than eight so next we moved through tricuspid valve into the rv where we find significantly elevated pressures with a systolic pressure of seventy two and an edp of twenty four. Notice that rb diastolic pressure will remain similar to the ira pressure. The absence of significant valvular disease next. We move through the pulmonary valve and into the pony artery here. The pressure measurements. Were sixty eight over thirty. Six was a mean. Pa pressure of forty seven pa. Sp is normally similar to that of the rv but we expect to see a step up in the diastolic pressure due to pulmonary vows preventing backflow of blood. We continue our journey into the pulmonary circulation with our balloon inflated and wedge ourselves into the distal pulmonary circulation. The wedge pressure approximates la pressure which we take our proxy of lv edp. In the absence of significant mitral stenosis. Our patients kohner capillary. Wedge pressure was estimated than six significantly above the normal of eight to twelve so in summary. This was super helpful. We nassau that. She's volume overloaded and confirmed a diagnosis opponent hypertension as a reminder as of the six world symposium on pulmonary hypertension the definition of is now immune pony artery pressure of greater than twenty danny. We know she has sinus noses. Defect on t. e. now we've seen these elevated pressures. How can evaluate the shunt fraction while. She's on the table. This is really great stuff. Let's dive right into it. So shut slow from the systemic circulation to the pulmonary circulation or so left to right shunt can be localized and quantified during a right heart. Cath by performing. What's called an symmetry. Saturation run or sat. Run or a shunt run and to do this as the catheter is passing through the great vessels to the pa. Or should i say as the magic school bus drives down the wonderful vascular that is the cardio pulmonary circulation. Small amounts of blood can be obtained and sent symmetry in each different chamber. So never gonna perform a complete sat run. We take the chambers from the proximal and distal. Sbc the proximal and distal the right atrium the right ventricle the pulmonary artery and the to obtain a true systemic saturation taking multiple samples in each chamber can also be done but are only necessary when the level of a suspected shunt is unknown. And you really want to identify where it is in which particular chamber so a left to right shunt detected when you detect an asymmetry. Step up where oxygenated blood from the systemic circulation mixes with dioxin jaded blood from the venous circulation up with more than seven percents is considered significant at the level of the great veins. And the right atrium. While i step up of more than five percent is considered significant at levels distance. The right atrium. The degree of left to right shunting can be quantified by calculating the ratio of pulmonary blood flow to systemic blood flow or the q p q s and this ratio is calculated using the fick principle for cardiac output and by making a few subjects. So i because the cardiac shunts will affect the mixed venous oxygenation or the pulmonary artery oxygen saturation a systemic mixed venus. Saturation needs to be calculated to essentially reflect pre shunt mixed venus. Oh too and this is defined by slams formula or three times. The sbc plus one times divided by four next. We make the assumption that oxygen consumption hemoglobin concentration. An atmospheric pressure are constant. This allows for many of the terms in the complex equation to cancel out leaving only the asymmetry saturation's to calculate the peak. Us ultimately wants simplified. The equation boils down to difference in saturation across the systemic circulation or a arctic saturation minus your calculated mixed saturation divided by the difference across the pulmonary circulation or the pulmonary veins sat minus the pulmonary artery. Sat at practically the pulmonary administration cannot be obtained without a transept Puncture or retrograde catheterization through the left side valves but in the absence of a significant right to left shunt. We expect the systemic arterial saturation and the venus situation. Thirty the same in other words. The left atrial. Saturation should be the same as the arctic. Saturation and so the pulmonary venice situation is often replaced by the stomach. Arterial saturation the arctic saturation. Ns equation. danny. That was such beautiful explanation about how to interrogate are cath saturation's for admiral shunting. The formerly went over to help us. Determine what we call the cue s where you know we can't get it noninvasive lee using echocardiogram again marai but a gold standard gray p being the cardiac output through the pulmonary circulation and q. S being card apple through the systemic circulation such that q s is a ratio of the put in the pulmonary circulation over the cardiac output systemic circulation. And given that normally everything is in a series without communication the ratio normally. It should be very close to one so when you go through the math. Danny how do you interpret the q. S beyond that. That's on it so as you say. In normal situations the pulmonary circulation and the systemic circulation should have an equal amount of blood flow so ratio should be one but when the pulmonary circulation has more blood flow going through it than the stomach circulation that ratio will become greater than one. And so what. We typically think of as a small left to right shunts is accused of less than one point five but when we think of a large left to right sean to wear a lot. More blood flow is going through the pulmonary circulation. A ratio of greater than too often indicates a larger left to right shunt and these are patients who often present symptomatically who require closure or some other procedure to.
"boston university" Discussed on Cardionerds
Masters in Business
Vincent Jackson’s Family To Donate His Brain To CTE Research In Boston
"The family of a former NFL player is donating his brain. Sarah Bartlett explains Why Vincent Jackson's family says his brain is going to Boston University to be researched for CTE, a deadly brain disease associated with repeated concussions or head trauma with the donation of family spokesperson says Jackson was the type of person who wanted to help as many people as possible. The 38 year old who played for the Buccaneers and Chargers, was found dead in a Florida hotel room last week. His cause of death is still
Vincent Jackson's brain to be donated for CTE research
"Military. The family of a former NFL player is donating his brain. Sarah Bartlett has that story. Vincent Jackson's family says his brain is going to Boston University to be researched for CTE, a deadly brain disease associated with repeat. Concussions or head trauma with the donation. A family spokesperson says Jackson was the type of person who wanted to help as many people as possible. The 38 year
Colorado's Morning News with April Zesbaugh and Marty Lenz
Former Los Angeles Charger Vincent Jackson’s Family To Donate His Brain To CTE Research
"Football standout donating his brain for research The New York Times is reporting that Vincent Jackson's family has donated his brain to Boston University to be research for CTE, The former wide receiver was found dead last Monday in a hotel room in Florida. The age of 38. The cause of death is still unknown. He reportedly had an alcohol problem. And years worth of research is the
AM Tampa Bay
Vincent Jackson's brain donated to Boston University's CTE Center
"Former Buccaneers star receiver Vincent Jackson may have been dead for three days before anyone called for help. That's according to a new medical examiner's report. Jackson's body was found in the Homewood Suites in branded on Monday, and hotel staff actually entered his room twice in the days before. Mistakenly thinking he was sleeping in a chair. Jackson's family says his brain is being donated to the Boston CTE study, which researches the effects of severe concussions. Cognitive impairments be behavioral abnormalities. Uh, mark MOOD instability, depression, anxiety, behavioral impulsivity, neuropsychologist Michael Schaumburg at USF, telling News Channel eight effects of CTE can only be studied actor and the victim dies. Sheriff's office says Jackson's family indicated he may have suffered from chronic
"boston university" Discussed on KCRW
"The afternoon with highs in the fifties and sixties, it's all things considered from NPR news. I'm Ari Shapiro in Washington, and I'm Elsa Chang in Los Angeles as the country tries to address racial injustice and police violence, much of the accountability and responsibility for that. Falls, two mayors and you surveyed is giving us a look at the attitudes of mayors on policing and how mayor's feel about the relationship between law enforcement officials and the communities they're supposed to protect. NPR political reporter Juana Summers got a first look at this new survey and joins us now. Hey, Wanna Hey there. Hey, So let's dive in. Tell us about this survey. What did it find? Yes. So, l said. This is an annual survey from Boston University and its of mayors who leads cities of more than 75,000 people, and it collected the results of more than 100 mayors. And that is about a quarter of all mayors of cities of that size. One of the biggest takeaways is that these mayors overwhelmingly acknowledged that black people are treated worse by the police compared to white people. Other views are more mixed. When they're asked whether black people distrust the police here is Katherine Levin Einstein. She's an associate professor at Boston University and helps around the survey. Mayors do recognize deep racial disparities in the experience of policing in America, and they in particular, see that experience as much worse for black people s O. They recognize this deep racial inequality, But at the same time that they recognize this serious problem, they're also unwilling to in large numbers recognized police violence in their own communities. So I want to just dig into what she's saying here a little bit. Roughly. 40% of mayors say they do not believe that police violence is a problem in their community, And the authors of the study told me that they did not see significant differences here, based on the race of the mayor, responding to the survey, so white and nonwhite mayor's alike said that police violence was not an issue it fairly similar rates. One place that there was some difference as you may expect was between Republican and Democratic mayors. Right Interesting. Well, something else is survey asked mayors about was funding for their police departments, something that has been a flashpoint in politics this past year. What did the survey results find? Yet found that the vast majority of mayors do not support sweeping changes to the funding of their police departments. 80% of the mayor said they believe their police budgets last year were about right on Lee about, 12% said They believe those budgets to be too big, which is particularly interesting, given the outcry that we have heard over the last year from some across the country. To defund police departments to re imagine these budgets and what public safety tactics could look like in local communities. Right? Well, did you get a sense from this survey for what types of changes to police departments that mayors are willing to support? Yeah, Broadly speaking, these mayors did not suggest that they support broader transformation of their cities. Local police departments, the reforms, they suggested, and the open ended questions in the survey where things that I would say arm or a part of the existing structures of these departments. I did call up Mayor James Butts of Inglewood, California who's also a former police chief. When I spoke with him, he pointed to cultural and leadership issues within police departments that he says need to be addressed. You have to look inside at your culture. How you police? How you think Look at your complaints and to receive And use those as a barometer of guide as what you need to do to change behavior and thinking in the department. And I should point out that butts is someone who does not believe that cutting police budgets is the answer. And on our conversation, he said that that misses the mark that it doesn't address the root of the problem entirely. And he believes that cutting funding of some might suggest would actually lead to communities like his being less safe. Course. This is all coming during a week in which President Biden has promised to put a focus on racial equity. Did that promise did it include anything about local policing? Yes. So we saw the president this week sign a number of executive orders that his aides have said are aimed at dismantling systemic racism. But none of the orders that have been signed so far, specifically addressed policing. We do know that during the campaign, Biden promised to address police misconduct through the Justice Department, and we should point out that his nominee to leave that department Merrick Garland has yet to be confirmed by the Senate. Is NPR Political reporter Juana Summers. Thank you Wanna you're welcome. In Wyoming, the name Cheney has been gold for decades. Liz Cheney has easily won all three of her congressional elections, and her father was a popular congressman before he was vice president. But after she voted to impeach former President Donald Trump for his role in the insurrection, the younger Cheney is getting pushed back at home. Wyoming Public Radio's Bob back reports. Wyoming. Republican Liz Cheney's says her vote was not a partisan issue and that Trump crossed the line are Republicans very fragile and we all have an obligation to ensure which doing everything that we're compelled to do by oath. Genie says. She hopes people in Wyoming will understand, but many don't Cheney joined in with the war on top, So I'm gonna say it's Pelosi's Warren Trump. That's GOP state Senator Anthony Bouchard, who quickly filed papers to run against Cheney and two year Cheers. The state Republican Party issued a statement critical of Channing and Darrin Smith, a former county Republican chairman who attended Trump's rally ahead of the riot at the Capitol, says Cheney must be held accountable. He's thinking of challenging her in a primary as well. I think that it's much bigger than what she thinks in 18 months from now. I don't think that people are gonna forget roll over and say, Oh, it was no big deal. In many ways. She undermined the principles of the people that put her in office. No state supported Trump more than Wyoming. That's why Carbon County became the first in the state to censure Cheney for her vote. The county chairman is Joey. Currently the fourth every point that was made by representative Cheney in our statement violated the quantifiable will, if you look at election results of the people of Wyoming, if actual evidence to the contrary wasn't brought, and at that time we didn't have evidence, but some supporters are coming to her defense..
All Things Considered
Personalized brain stimulation alleviates severe depression symptoms
"Two studies out today suggest ways to improve treatments for depression and obsessive compulsive behavior. Using brain stimulation. Thea Pro just delivers pulses of electric or magnetic energy to certain areas in the brain. Scientists report that stimulation is more effective when it is customized for each patient. MPR's Jon Hamilton has more Brain stimulation is usually reserved for people who haven't been helped by drugs or other treatments. People like this woman in her thirties who had severe unrelenting depression, the world was slow. And gray and flat. Everything kind of tasted the same. No actual sense of enjoyment or No ability to imagine NPR agreed not to use the woman's name to protect her medical privacy. After five years of searching for help, she got into a study run by Dr Katherine Scan. Gus of the University of California San Francisco. Scandals is part of a team trying to improve deep brain stimulation, which implants wires in the brain to deliver tiny pulses of electricity. Traditional deep brain stimulation has typically stimulated in one location. In every patient without really an understanding of how that effects each individual's depression symptoms. Scandals thought she might be able to relieve the woman's depression using a different approach. So she created a map of her patient's brain that showed which area was associated with each symptom. She had an iPad and she marked off her level of depression and anxiety. An energy level in response to each pulse of neuromodulation. Then scandals used that information to design a deep brain stimulation system that monitored these areas and delivered pulses on Lee when there were signs of trouble. Our goal is to develop a brain pacemaker. That can nudge these depressions circuits back into their healthy state and keep them there. And for this patient, it worked, she recalls. The first time doctors stimulated one particular area of her brain. I wasn't really expecting anything to happen, and then suddenly It was this kind of wash off the sense of pleasurable happiness and glee, and I literally think I giggled. She says The implanted stimulator she went home with is still doing its job. Months later. The world is Is back. I'm back. I feel like myself again. A personalized approach to brain stimulation also seemed to help people with obsessive compulsive behaviors. Trade. Grover, a graduate student at Boston University, was part of a team that studied people who had thoughts that wouldn't go away or behaviors that they felt compelled to repeat, checking whether we've switched the stove off or not. Have you washed her hands enough in, particularly in times like ours today in the pandemic, Such behaviors can be exacerbated. The team knew that these kinds of behaviors are linked to problems in the brain's reward network. So they studied the activity in this network for about 60 patients. Then they devised a unique stimulation treatment for each person. Grover says The treatment sends pulses of alternating current through electrodes placed on the scalp. It allows us to stimulate the brain. And mimic the kinds off Ray to make activity patterns that are typically associated with healthy behavior, He says. People who got the treatment instead of a placebo got better. By the fifth day of stimulation, obsessive compulsive behaviors had significantly reduced. On average. There was a 28% reduction, and Grover says the treatment works best on people with the most severe symptoms. Both studies appear in the journal Nature Medicine. Jon Hamilton NPR news
All Things Considered
Personalized brain stimulation alleviates severe depression symptoms
"Two studies out today suggest ways to improve treatments for depression and obsessive compulsive behavior. Using brain stimulation. Thea Pro just delivers pulses of electric or magnetic energy to certain areas in the brain. Scientists report that stimulation is more effective when it is customized for each patient. MPR's Jon Hamilton has more brain stimulation is usually reserved for people who haven't been helped by drugs or other treatments. People like this woman in her thirties who had severe, unrelenting depression. The world was slow and gray and flat. Everything kind of tasted the same. No actual sense of enjoyment or No ability to imagine NPR agreed not to use the woman's name to protect her medical privacy. After five years of searching for help, she got into a study run by Dr Katherine Scan. Gus at the University of California San Francisco. Scandals is part of a team trying to improve deep brain stimulation, which implants wires in the brain to deliver tiny pulses of electricity. Traditional deep brain stimulation has typically stimulated in one location. In every patient without really an understanding of how that effects each individual's depression symptoms. Scandals thought she might be able to relieve the woman's depression using a different approach. So she created a map of her patient's brain that showed which area was associated with each symptom. She had an iPad and she marked off her level of depression and anxiety. An energy level in response to each pulse of neuromodulation. Then scandals used that information to design a deep brain stimulation system that monitored these areas and delivered pulses on Lee when there were signs of trouble. Our goal is to develop a brain pacemaker. That can nudge these depressions circuits back into their healthy state and keep them there. And for this patient, it worked, she recalls. The first time doctors stimulated one particular area of her brain. I wasn't really expecting anything to happen, and then suddenly It was this kind of wash off the sense of pleasurable happiness and glee, and I literally think I giggled. She says The implanted stimulator she went home with is still doing its job. Months later. The world is Is back. I'm back. I feel like myself again. A personalized approach to brain stimulation also seemed to help people with obsessive compulsive behaviors. Trade. Grover, a graduate student at Boston University, was part of a team that studied people who had thoughts that wouldn't go away or behaviors that they felt compelled to repeat, checking whether we've switched the stove off or not. Have you washed her hands enough in, particularly in times like ours today in the pandemic, Such behaviors can be exacerbated. The team knew that these kinds of behaviors are linked to problems in the brain's reward network. So they studied the activity in this network for about 60 patients. Then they devised a unique stimulation treatment for each person. Grover says The treatment sends pulses of alternating current through electrodes placed on the scalp. It allows us to stimulate the brain. And mimic the kinds off Ray to make activity patterns that are typically associated with healthy behavior. He says. People who got the treatment instead of a placebo got better. By the fifth day of stimulation, obsessive compulsive behaviors had significantly reduced On average, there was a 28% reduction, and Grover says the treatment works best on people with the most severe symptoms. Both studies appear in the journal Nature Medicine. Jon Hamilton NPR news
AP News Radio
King honored at Boston University, his alma mater
"Remembering Martin Luther king junior who once said darkness cannot drive out darkness only light can do that Margaret Wong is the president of the Southern Poverty Law Center and on this MLK day she reflected on the uprising at the capitol less than two weeks ago he pointed out that he does not drive out hate only love can do that and it can be very hard to hate those urges to love those who hate you but it is more important than ever that we understand what Dr but he also important to help the poor Martin Luther king led the fight against poverty and we need to restore that and one and stuff but I didn't administration is a start but we have to commit ourselves to enabling their efforts to be felt and doing what we can in our communities to help one another I'm shelling out there
WBZ NewsRadio 1030
"boston university" Discussed on WBZ NewsRadio 1030
"Tunnel route three south new problems that all down password 18 24 South is a little stop and go at the beginning. Miking WBC's traffic on the three we've got the clouds around will have the rain around later on after midnight or so we'll start to see the Precipitation over spread the area and it will become heavy towards daybreak. Tomorrow. Cold enough temperatures outside of 4 95, north and west could see a little bit of wet snow mixing in overnight Tonight. Temperatures should be about 40 at the coast. For tomorrow. It'll be rain heavy at times in the morning, tapering off of the afternoon temperatures into the upper forties. The wind sticks around for Saturday night. Mostly cloudy. Low of 34 real fields in the twenties. Sunday. Ah, windy day. Some sunny breaks through the clouds temperatures into the forties, but real fields twenties and thirties on Sunday looks like we'll have some sunshine for Monday. With highs in the forties slide local and fiercely independent. This is WBZ news radio. Good afternoon. I've been Parker. Here are the five things you need to know. At 4 45 President elect Joe Biden pledging to ramp up Corona virus vaccines under the Defense Production act, as states have warned their supplies are running out. Just over a year after the Corona virus was first detected. The death toll from covert is now topped two million worldwide. Boston University today began giving out vaccines on campus. The school has received 500 doses. House Speaker Nancy Pelosi asking for a review into capital security following last week's violence.