35 Burst results for "Blood Cancer"
"blood cancer" Discussed on WTOP
"25. At 45, start colorectal and breast screening. At 50, discuss lung screening with a doctor. Find resources for free and low cost screening at cancer dot org slash get screened. This is a public service message from the American Cancer Society. Did you know that there are currently more than 20,000 individuals in the Washington D.C. metro area living with blood cancers? Join the leukemia and lymphoma society in their mission of fighting blood cancers and improving the lives of patients and their families by attending an inspiring event celebrating the extraordinary achievements and brighter future in blood cancer research and survivorship at the 36th annual leukemia ball on Saturday May 13th. The leukemia ball is one of D.C.'s largest and most anticipated nonpolitical black tie events, bringing people together to save lives. This legacy philanthropic black tie event will feature an impactful mission program silent and live auctions, cocktails and plated dinner featuring headlining entertainment from critics choice nominee magician and comedian Justin willman continue to dance the night away while enjoying the Grammy Award winning DJ stylings of DJ jazzy Jeff. For more information and to purchase tickets, please visit leukemia ball dot org. With morning traffic is at its worst, Jack Taylor is at his best. Join John and Michelle and Jack on traffic. News. When you see smoke on the horizon, you turn on WTO. Because WTO P is first with the news when seconds count. Day or night, our reporters are live on the scene when news happens. We're here in del Rey. Breaking news from Reston. We're in hyattsville. So whether it's a fire, or some other breaking story, you'll be up to date. Everything you need every time you listen. Bundling up against the morning chill at WTO, three 28. Try to get weather on the aids back to Carlos Ramirez in the traffic center. Thanks Ian
"blood cancer" Discussed on WLS-AM 890
"Do. But I'm obsessed with having the best possible show. So I have this fomo, fear of missing out. So I sit there every single second of every day of my life when I'm not previously occupied or spending time with my kids or Paul or someone. And I scroll, and I see this video that's gone really nuclear. And it's Scott Adams. Now, I believe it wasn't even Dilbert creator to comic, I believe it is, right? So his claim to fame is a famous comic Gilbert. Now, I follow Scott on various social media platforms, says a lot of things I agree with, a lot of things I don't. But Scott had previously been self admitted very kind of pro vaccine for COVID that this thing is pretty good and effective and going to work out whatever I had hesitated. I've told you many times I'll say again, I am waged in a multi month now yearlong battle with significant partner in my radio show, which has been widely publicized over vaccine mandates. You know that. I say that because it's a personal matter to me, because early on, when the vaccine, I mean, first came out. And when I say first, I mean within days, I got a notification because I had a blood cancer and almost non functioning immune system. Sorry, if you've heard this story before, but it's relevant here. That I was eligible for this. And upon recommendation of not just one, but many people in the healthcare space because of my condition, they were afraid if I had caught COVID that I, I mean, I might not make it. I had no immune system and nobody knew back then really how. Well, they knew, but they were hiding really how fatal this stuff was. So nobody had really good accurate information. So in the worst medical mistake of my life, out of fear, which was dumb and stupid. I took this thing, but I want to be clear if you go back and listen to my podcast and I encourage you to do it because there's a lot of candidly bold stuff out there. I was never one of the ever one of these people who jammed this thing down your throat ever. And I believe me, I strongly encourage you to go and listen. As a matter of fact, I was very skeptical even about myself about what the long-term effects is we're going to be. And I laid out my situation and why I made the decision I did, which I now, and I think almost immediately afterwards regretted. Matter of fact, I was one of the guys who went very few other people in radio reached out, put my job on the line over fighting this vaccine mandate, a story that's been again widely publicized. Especially you know the story if you're a listener to this show. So to see a bunch of people now who are very not only pro vaccine, but people who wanted the vaccine for you and encourage you to take it kind of change their mind. Kind of little lady now, I think it's good that they've changed their minds and I'm not mad at anyone or angry at anyone. I think it's a mistake for us to I get the anger. I understand it, but I don't think it's productive now to solving the problem. We have a problem. And the problem is, I believe this vaccine is going to be one of the biggest public health debacles of our time. I don't think the long-term side effects are obviously understood. So to see a guy like Scott Adams, I like and I don't just say that. I hope I like him and then they go and trash him. I like Scott, we agree on some stuff we disagree in some stuff, but to see him put out this video that went viral by Jim cue it up for me, cut one, where he says, and I disagree with the language he calls anti vaxxers. I'm not an anti vax person. That's the left language at all. I'm a pro science person. That's why I'm skeptical science is skepticism, right? He basically says, listen, you anti vaxxers. You won. Here, listen to yourself. The things they're not worrying about is what I have to worry about, which is I wonder if that vaccination 5 years from now. Because really the anti vaxxers, I think we're really just distrustful of big companies and big government. That's never wrong. It's never wrong to distrust government. It's never wrong to distrust big companies. So if you just took the position, let's just distrust everything the government did. Well, you won. You won. You won completely. I did not end up in the right place. Agree? You would all agree with that, right? I did not end up in the right place
AP News Radio
Military probing whether cancers linked to nuclear silo work
"The U.S. Military is looking into cancer found among multiple crew members at a nuclear missile base. In slides from a briefing obtained by The Associated Press, a lieutenant colonel in the U.S. Space Force says 9 officers assigned over the years to maelstrom Air Force Base in Montana, all developed a type of blood cancer, non Hodgkin's lymphoma, and one of the officers has died. The base is home to a field of silos for minuteman three intercontinental ballistic missiles, and the miscellaneous worked deep underground in a reinforced bunker. More than 450 former missileers are serving as Space Force officers, including at least four of the 9 identified. The slides say there are indications the disease may be linked to their service, and that the disproportionate number presenting with cancer specifically lymphoma was concerning. In a statement to the AP and air force spokeswoman says senior leaders are aware of the concerns and medical professionals are gathering data to learn more. I'm Jennifer King
The Daily Meditation Podcast
"blood cancer" Discussed on The Daily Meditation Podcast
"When you're first diagnosed with multiple myeloma, a rare form of blood cancer, it's easy to be overwhelmed. But it's important to realize that there are prescription treatment options available for adults that you may discuss with your healthcare professional. Become better informed and find out what's possible with treatment. Start the conversation with your doctor today about the potential benefits and risks of treatments for multiple myeloma. This message is brought to you by Janssen. Welcome to the daily meditation podcast. I'm Mary meckley, and I welcome you to day 6 of the series we're exploring to awaken your inner joy and in today's episode you are guided using the different meditation techniques you've explored all week long, and if you are joining us now for the first time, you are in the right place and welcome. If you are a longtime listener, I welcome you and honor you for giving yourself such a beautiful gift as you do each time you meditate. This week, you'll have been putting some closure on this year as you get ready to usher in a brand new year. And you've had a special challenge this week. Your challenge is to do one thing every day that's going to allow you a little more inner joy. This is also a time for you to freshen up your meditation, space. So I invite you to take a look around the space where you are meditating, you may be in your special meditation space or you might be out and about meditating wherever you can make it happen. That is perfect. The goal is to have you meditate regardless of where you meditate. But if you're able to create a space, that's personalized that seems to backing you into sit down and meditate. This is going to help
The Bitboy Crypto Podcast
"blood cancer" Discussed on The Bitboy Crypto Podcast
"Sift your way into the holiday spirit with Starbucks peppermint mocha. Sweet creamy whip, chocolatey swirl, a dash of peppermint, steamed milk, and espresso. It's a little gift to give yourself. Find your cheer on the Starbucks app today. When you're first diagnosed with multiple myeloma, a rare form of blood cancer, it's easy to be overwhelmed. But it's important to realize that there are prescription treatment options available for adults that you may discuss with your healthcare professional. Become better informed and find out what's possible with treatment. Start the conversation with your doctor today about the potential benefits and risks of treatments for multiple myeloma. This message is brought to you by Jansen. Geico asks, how would you love a chance to save some money on insurance? Of course you would, and when it comes to great rates on insurance, Geico can help. Like with insurance for your car, truck, motorcycle, boat, and RV, even help with homeowners or renters coverage. Plus, at an easy to use mobile app available 24 hour roadside assistance, and more, and Geico is an easy choice. Switch today and see all the ways you could save. It's easy. Simply go to Geico dot com or contact your local agent today. Common question newcomers to the crypto space ass all the time is where should I keep my crypto? And the quick answer is anywhere, except in exchange. In crypto, it's important that you have self custody of your coins, instead of letting a third party do that for you. Not your keys, not your crypto. This year, we've seen insolvency issues turn less responsible platforms of this community on their heads. And the contagion effect, this has affected millions of users.
KCBS All News
"blood cancer" Discussed on KCBS All News
"Treatment resistant leukemia. But I am so excited about this story and what it potentially platoons. The 13 year old patient is named Alyssa. She went into remission a month after receiving what's known as base editing technology. It modifies donor cells to destroy T cells in the body, and months later, she continues to improve. For more, we're joined on the case ABS RingCentral newsline by doctor wasim Qasem, Professor of cell and gene therapy at university college in London. He led the program that manufactured Alyssa's donor cells. And can we begin a professor or doctor qassem? Thank you so much for being with us. I'm wondering, it sounds to me as if one of the differences here before some of the prior efforts at this type of treatment is that it is the donor whose cells are being treated, not the patients. Yes, sir. Good afternoon. Thanks for the thanks for the call. You're absolutely right. There's quite a few T cell therapies around the cold car T cell therapies where patients own immune cells are collected and engineered and given back. And we've had a program for some time to try and use donor cells and engineer them in such a way that you can use them in multiple patients. And those extra steps require gene editing. Now, the difference for at least treatment was that we've applied a new technology for the first time, which is called base editing. And that's pretty smart technologies come out of MIT and it essentially allows us to change single letters of the DNA code one at a time, which is the which is a new and exciting part of this type of treatment. How is alysa doing? Because actually, sir, we treated her back in the start of May, she received herself. It's been over 6 months. And we're very cautious to say, well, okay, she's doing well. Her bone marrow is clear of leukemia she's having repeated sampling and tests done. And we're very cautious to not try and predict what's going to happen because we know certainly the first 6 months in the first 12 months, let's say, a crucial for these patients to know if it's really truly gone or whether there might be some chance of it coming back in the future. So she's doing really well she's at home and in fact, I think she's quite enjoying some of the attention that's come from the release of the story. Well, she is a teenager, after all. She's remarkable teenagers. Teenagers, of course, it can go both ways, consciousness has been remarkable and engaging and has been happy to help all the way through. Fabulous. So I love this. I'm very excited about all of this. And I think everybody who's listening is excited about this. But this technology may be able to be used for more than leukemia. Leukemia is a blood cancer. Will it be able to be used to treat other cancers and potentially other diseases? And if so, when yeah, so look, it's really important to say that we're dealing with blood cancers, the keen is a lymphoma. And those have so far been, if you like the easier end of trying to treat cancer using cell therapies and immune therapies. So it's harder to treat some of the solid cancers prostate and breast and so on. They're just more challenging. They've got more difficult types of protection against cells and against chemotherapy and so on. So it's much harder to treat those cancers. The other area where this technology will be applied and it's imminent is to try and correct certain gene changes that are inherited and cause diseases, one good example of that is sickle cell where there's a single change in the DNA code that makes the red blood cells behave abnormally. And so there are program. We're not doing those treatments, but other people will. And I'm pretty sure sometime next year the studies will start to try and treat those types of conditions with this type of technology. Yeah, we're thrilled. We're so excited to hear about this in the treatment of leukemia and what it may portend in the future. Congratulations. Doctor wasim Qasem. Thank you so much for joining us as we talked about this wonderful treatment. It's a gene editing technology that treated a teenager with treatment resistant leukemia and was successful
"blood cancer" Discussed on Squawk Pod
"Who have already. And then you use it with keytruda, which also ramps up your immune system. But you put the messenger RNA in, it codes for those neo epitopes, but it's not cancer, but it shows the mutated part of the genome. You put that in, so your cells get all ramped up that we don't like this. But they know what to attack. They're teaching other things to attack the tumor cells have those neoepitopes. But you're not introducing tumor cells. You're just introducing the messenger RNA to make the neopets. I mean, that's like the Holy Grail that we've been looking for and looking for since we've got a lot of work since Nixon declared the war on cancer back in the 1960s. Had a lot of holy grails, but if you can actually personalize it and do it in an affordable way. And I guess that's the question too, how much does this cost? If you're doing talking personalized medicine, you're usually talking some pretty high redheaded kids and I've got, you know, it's fair skin. And I've hit squamous basal in situ in situ melanoma can be pretty scary. Well, that's like before stage one, but any of it, you worry, and I got things that I've never seen before. And most of them, there's nothing wrong with them, but they're horrific looking hair is growing out. Enough information, but we see your point. Every time I go in, I get scraped every 6 months too. To see what's happening again, fair skin. Right. What's most promising is the idea that they're going to go after other stuff too. Right. Exactly. So before they even get before this is commercialized or approved or anything else, let's start testing it with food on the steps. All right, that's great news. Join us now. Moderna CEO Stefan von Sel, when was the disruptive welcome? Good to see you. We did the disruptors day. It was about two and a half, maybe three months ago in the trials were ongoing. You had some positive data from previous trials, but this is more definitive. Yes, good morning, drew. We are very excited because this is definitely the study as read out by morphs out. And as you say, the P value statistical significance of a study is real. This data are real. We designed a study to be powered. As you know, the control arm was kitchen drawer alone, which is the gold standard in cancer. And so showing a 44% reduction of recurrence or death is a big deal for cancer patients. So we are very excited. We are moving very quickly with Merck on two phase three for this study, of course, we'll talk to regulators to see what we can do to accelerate this as much as we can. And we believe from a mechanistic standpoint that we are able to teach T cell how to organize your own cancer. And so we want to go aggressively in many different cancer at the same time in phase three in parallel, because we believe we will keep you at work. This should work. And we believe it might even be places where KT two doesn't work, but could you draw plus more than our PCV? Customers can so vaccine could work. So it's a big day for patients. The proof of concept, you're much more comfortable with now. So there's solid tumors. There's blood cancer. There's all kinds of cancers. They're all personalized to fund, but do they all have these neo epitopes that I don't want to get too into the weeds here, but do they all have different characteristics than normal cells that you can use to design the mRNA vaccine against? Almost all cancers have that. So you could theoretically go after a lot of different solid tumors or even blood cancer. So that's correct, drill. So at this stage, we think that solid tumors, which is around 90% of cancer cases are the right place for us to start. As you know, cancer is in mutation of healthy DNA, now thanks to sequencing technology, we're able to basically look very precisely what mutation do you have in your cancer right now compare this to a healthy cell of your body and design a product within a 45 days a day as soon as maybe 30 days just designed for you to teach your T cell hard to recognize the mutation of your cancer. So the keytruda cancer cells are devious because they try to fool the immune system into not recognizing it. So the keytruda sort of tries to strip away that the sort of the mask so that your immune system can see it. And then this ramps up the number of T cells that go after the specific tumor because the T cells should already see that tumor. They already see what are you doing multiplying the number of copies so that it they make many more your body makes a lot more T cells because they already know they see these neoepitopes already in the tumor. It's introducing more copies, makes it much more potent. I don't think it's actually more copies, Joe. I think it's teaching new epitopes that the T cell don't recognize in the data we presented at asco in the spring of 2019. We show that a lot of cancer patients that we take the blood before treatment and after, before treatment, a lot of T cells don't recognize some of the epitope that we know exists in a cancer cell because we sequenced it. And we call that instruction in our product and three or four those are three weeks apart. Three or four days after we take the blood again of those cancer patients and we see now thanks to all products, we have T cell can recognize more epitopes. I think that is really important in terms of recognition of new epitope. And more epitopes so that as you can say evolve, you can keep it in check because there's 34 mutations in everyone product for patients. Well, your stock was up about a dollar and a half earlier when we were talking about this. I think it's almost a 15 point. So would you always use keytruda with solid tumors or would it always be in conjunction with keytruda? And what's your next, what else needs to be handled? Long cancer, or it's all scary, because everything metastasizes and goes everywhere. So this would give you a way to introduce it into the body where it could go wherever it was needed. It seems like as you can't remove all the tumors. That's the problem. And that's why we're so excited that we'll be technology drew, which is exactly what you say, which is if we're able to prove to them to teach T cell of a cancer patient to recognize mutation of that specific cancer that it could not recognize before. That's a massive medical step forward. And so we believe it should work in many, many solid tumor. Again, we're going to have to prove it for clinical studies, but that's our scientific belief. We believe we could work in different settings when this one this was adjuvant after surgery. And so we're going to be using the strength of a balance sheet in a Moderna as $17 billion of cash, Merc obviously is very well capitalized. And as you know, for these 50 50 partnership, we share the cost 50 50 and we shove a profit 50 50. And so you're going to see us together very aggressive, as you know, Merck has done an amazing job with cathedral to test a lot of tumor at the same time. And so you should expect the Moderna partnership to do the same thing. We're going to be very aggressive for the sake of patients. The study, the trial that you were just talking about, how many patients are in it, how long has it run? Yes, it's a great question, Becky. So it is a 150 patients. It was designed to be statistically powered. So we always wanted to know is it working or not? We didn't want to have results. And as you know, because it's so hard as a disease, it was critical. So that's why the P value at 0.0266 really mean that these data is for real. And we did two patients out of three got Moderna and PCV. One got KT dry alone. We did less on the control arm because there's, of course, a lot of data out there on KT drive through its own clinical studies. And so that's how Merck and those designed the study. So it's real. So the blind, the blind study though, was they got keytruda. Nobody got
"blood cancer" Discussed on WTOP
"Charity of the month is the leukemia and lymphoma society. Join LLS for life the knife is October, as they gather in Frederick, Baltimore, Rockville, Reston in Washington, D.C. to bring light to the darkness of cancer. You won't want to miss this family friendly evening in memory and in honor of those who have been impacted by blood cancer. Learn more at light the night dot org slash mid 18 for more information visit WTO P dot com. Search charities. Hi, I'm rich McKenzie, owner of metropolitan bath and tile. I had a customer call me recently and ask if I could recommend someone that could do a small repair in her bathroom. A little surprised at the question, and I said, misses shepherd, we've done two other bathrooms for you. Why wouldn't you have us do the repair? She said, oh my, I didn't think you'd be interested in such a small job. So it got me thinking. I wonder how many other folks out there wonder the same thing. While I'm here to tell you that at metropolitan bath and tile, we love small jobs. If it's in a bathroom, we're happy to do it. Everything from recall to a whole new bathroom. It doesn't have to be a big job to make us happy. Small jobs are large. Serving our customers with honesty and integrity, that's what makes us happy. So call us at one 800 new bath, or visit us at metro bath dot com. That's metro bath dot com. Bathroom remodeling. It's what we do. It's all we do. Whether you're migrating to the cloud from the cloud or between clouds, protecting your data and ensuring business continuity are critical priorities. Veritas can help you build a unified multi cloud strategy with resiliency at its core to help ensure strategic and mission critical decisions. Our enterprise data services platform is designed to give government agencies the confidence and control to transform, protect, and optimize your multi cloud. Visit veritas dot com forward slash government for more information. This is WTO news. Three 53. She was expressed. I'm Ross crystal, but cast of jackass led by Johnny Knoxville and Jeff tremaine battle it out to see who will win the grand prize for their chosen charities in the season finale of celebrity family feud. Steve Harvey hosts season 8 prawns to a close Thursday night at 8 on ABC. Gloomy and Reynolds rally around max as he deals with the fallout from Helen's decision. Franco stars as max
"blood cancer" Discussed on WTOP
"Now the Kremlin has lost apparently a large number of spies. This morning, WTO national security correspondent JJ green has more. Since the war started, Russian spies have come under intense scrutiny around the world, especially in Europe. We've taken some pretty concerted effort against them. Richard Moore, chief of MI 6, Britain's secret intelligence service. Across Europe, roughly half the last count of something in north of 400 Russian intelligence officers operating under diplomatic cover have been expelled. And that he says has cut deeply into Russia's ability to spy and gain an advantage in this war. We reckon in the UK, that's probably reduced their ability to do their business to spy for Russia in Europe by half. And recently, there have been a couple of highly publicized blunders by Russian illegals, deep cover spies, who were caught and are now facing decades in foreign prisons. JJ for a while now people have been reporting on Vladimir Putin's health and whether or not it was good, and apparently there's some new information on that. Yeah, we've heard everything from Putin being ill with blood cancer to having Parkinson's, but more Richard Moore, who you heard in these pieces, who really does interviews, said last week at the Aspen security forum, they, British intelligence, MI 6, have no evidence that Putin is ill. Now the question is, how much visibility do they have into Putin's personal life and that was a question that was put to him and he declined obviously to answer. Deviled national security correspondent JJ green with the latest of the war between Russia
How to Live A Fantastic Life
"blood cancer" Discussed on How to Live A Fantastic Life
"Just got out of surgery, so no. I'm like, okay, okay. Tell me what it does. Anything. I still believe it. I'm gonna be, I'm gonna have my cycle. Well, two weeks from that surgery, I woke up and I started my cycle and I just sobbed. I sobbed, it was the best thing ever. I called Kevin, and I'm sobbing in the phone and bless his heart. He was freaking out because his wife just had surgery and now she's calling him because, you know, she sobbing by told him that my cycle started. And I was so excited about the grocery store to buy vivid and hygiene products. I couldn't wait to load up my cart. I had the worst cramps ever. I'm like, this is amazing. I cramping again. Cashiers like this. What's up? Woman is crazy, right? But after that, two weeks later, we got pregnant and we had baby number two, miracle a little too. Yes. Pretty incredible. But along the way, Kevin had some obstacles too because I guess nature didn't give enough to you guys to handle so they wanted to give you a little bit more of your plate to handle as well. Another curve ball is you would say, right? Another curve ball. The curve ball. So we talked about baby number three. And by the way, for those keeping store at home, we no longer talking about more kids because every time we do, we have another curve ball. Yes. But we're talking about baby number three. And all of a sudden, I find this lump in my jaw. And it ends up looking like a golf ball. And oh gosh, we go to specialist and they inform me at the time I was age 36. And they informed me that was non Hodgkin's lymphoma, which is a form of blood cancer..
The Dan Bongino Show
Dr. Peter McCullough: Spike Proteins by Vaccines Could Be an Issue
"For a guy like me who's recently hopefully recovered from lymphoma I'm in remission now And my wife was an autoimmune disorder herself and lupus If that turns out to be the case and I understand some preliminary study you know you were very cautious in your approach to it as well But if it turns out that we are producing spike proteins long term What could that mean for people with autoimmune difficulties and people with various types of cancers blood cancers and immune system cancers I think it's going to be a matter of degree If it's one or two shots and it's echo cells and there isn't much passage to daughter cells this thing can in a sense burn itself out or be cleared out over time Bruce Patterson who leaves a company called Intel DX doing terrific work is formally professor at northwestern and Stanford He's actually shown in the respiratory illness that the spike protein is in the body a long time to end but up to 15 months in CD 16 positive monocytes And I did have him on my show and I asked him about what has he seen in vaccinated people And in fact he does have samples He's seen both the S one and the S two segment of the spike protein in humans after vaccination as long as he's observed them So for a month I asked him I said can you predict how long it's in the body He said probably over a year SARS CoV-2 the virus And then the spike protein installed in the body with vaccination It has a persistence in the body That's the reason why people feel bad There's a long COVID syndrome And I estimate is there any other infection that's similar to this He said yeah there is I said what is it He said Lyme disease Lyme disease does an install of the organism called borrelia bardia It takes forever to clear out lime That's the reason why people get this post lime syndrome So I think people who are immune deficient people with lymphoma they've had chemotherapy or radiation or they have other autoimmune illnesses This could be a
The Dan Bongino Show
Are We Close to a Cure to Leukemia & Lymphoma?
"So you had mentioned before and I know some of the treatments have gotten very advanced I know therapies and even the chemotherapies gotten very targeted I went through a lot of that But are we close to a cure and do you think the money we can raise here will help us get to a cure Maybe it may be in my lifetime I mean I'm 47 I mean that's the whole time in 2021 alone LOS helped to advance nearly half of the blood cancer treatment approved by the FDA and in the past year 5 years alone we've helped to advance 75% of those treatment options So those numbers are definitely giving us hope that they're the cure
The Dan Bongino Show
Staggering Statistics on People Diagnosed With Blood Cancers
"So Ari when I was going through treatment I was out at both Sloan Kettering and MD Anderson and you see the devastation of this disease I would be sitting there waiting for radiation and chemotherapy and one moment that really stuck out to me as I was getting treatment one day and I was talking to this woman and she told me she'd been given basically a month or two to 11 and she'd been dealing with the disease forever And it's just kind of hit me because mine had been diagnosed early at stage one That even though we've made tremendous advancements against leukemia and lymphoma those advancements aren't enough A lot of people a matter of fact I saw in some of the statistics a third of people don't live 5 years after a diagnosis Is that accurate It is Yeah we're getting closer and closer but yeah just like you said more than a third of patients don't survive after 5 years How many people per year are roughly diagnosed with this dreadful disease these blood cancers leukemia and lymphoma What's the give me a rough idea of how prevalent this problem is I don't have a number on it per year but about a hundred every 180 seconds someone in the U.S. is diagnosed with a blood cancer
The Dan Bongino Show
How Your Donations for Leukemia & Lymphoma Society Work
"As you know this is political show but not everything in life is political thankfully right And one of the things that wasn't political for me was when I was diagnosed with cancer last year it was a really traumatizing moment as it would be for anyone is diagnosed with lymphoma Here to talk about lymphoma and to help us raise some money to hopefully decrease the number of people who ever have to have that moment again is already Dylan from the LLS leukemia and lymphoma society Ari thanks for joining me really appreciate it Thank you so much for having me I appreciate your time No listen this is obviously a very important topic to me We raised a lot of money for the LLS last year My daughter Isabel thought it was really important because this is such a devastating disease and this year we're looking at top that We have great listeners in this audience The website if you'd like to donate folks bongino dot com slash LLS Ari about leukemia and lymphoma all of the money that's raised Where does it go What is it Is it research Is it assistance What happens with the money Yeah so the funds that our campaigns raise it goes through a few different things It goes to continuing research for life saving therapies like targeted immunotherapies that are saving thousands of lives It goes towards blood cancer information education and support for our patients and our families It goes to support our patients in their communities and also to drive policies that are increasing development and access to new
"blood cancer" Discussed on Daily Pop
"To him and, you know, this massive hit, I would do anything for love. It was just solidified him. And what I liked about him is he was different and he was himself. Yeah. You know? And he used it theatrics and he used his weight and all that. You know, even the name meatloaf, it was just unusual, but he used it and he used it well. And of course, the Rocky Horror picture show, I mean, he's just gonna be he's iconic. 100% definitely, you know. And you know the hits just keep on coming. We've also learned that just moments ago comedian Louie Anderson died this morning after a battle with cancer. He was only 68 years old. Yeah, it was a blood cancer and, you know, I've worked with Louie many times. And this is the thing about comics. They start out in comedy, but he had a great career. I mean, even in his later age, he got the Emmy for baskets. And that's the beauty of stand up comedy is that you can write books, you can do stages. You can do acting. He will be iconic in coming to America. He worked in the McDonald's. But when I say the nicest guy, Terry, he was the nicest, and he was a joy to work with. Always laughing. He would see me on the red carpet. This is years ago. And he would come and give me an interview. And I never, ever would forget that, because he never forgets who his comedy brothers and sisters were. So rest in peace to all RIP everybody. You remember yesterday when Lonnie became a Christian expert? I just want to point that out for everybody. If you did not know right here on this show. I have to ask a question because the internets are buzzing because people think that west side story star Rachel zeigler just blew her chance to win an Oscar. The actress posted a dramatic reading of Britney's recent tweets about her sister, Jamie Lynn, and some people are pissed. Take a look at this. Uh oh. Please,.
The Charlie Kirk Show
Nurse Sees More Children Die From the Vaccine Than COVID
"Meanwhile, a nurse can cut one O 5 says she talks about how they're seeing more kids die of the vaccine than of COVID her words cut one O 5. My name is collet Martin. I'm an RN. I have 17 years, 12 years oncology, and the past 5 years I've been afloat resource nurse to all the different floors in the hospital. I'm extremely concerned with the IDA mandating this vaccine for our children. The reactions we were seeing in the hospital with adults are terrifying and they're being ignored. Just some examples of post vaccine reactions or blood clots. Heart attack strokes encephalopathy, heart arrhythmias such as atrial fibrillation. I personally had a patient die three months after his vaccines at pericarditis, which we know is an own side effect. Diagnose 30 days after a shot, no mention to VAERS. Majority of our nurses nurse managers and some doctors do not even know what theirs is. I've spoken to our chief medicine, managers, other nurses, and why we're not reporting to VAERS, and the most common responses, what is VAERS? We have chemotherapies that we know have side effects causing blood cancers such as leukemia and ten plus years after giving the drug. We know this because we have real long-term trials on these drugs. We are not just seeing severe acute reactions with this vaccine, but we have zero idea what any long-term reactions are. Cancer is autoimmune infertility. We just don't know. Our children are not even at risk for this. As of now, we have more children that die from the COVID vaccine than of COVID itself. Most people don't even know what VAERS is, she
The Eric Metaxas Show
"blood cancer" Discussed on The Eric Metaxas Show
"Been happening? You mentioned something about angels and Costa Rica. I love this stuff, so what's cooking? Well, let's start in November. November was a really busy month. I was only home four days, although admittedly, 5 of the missing days were because I went to Texas for Thanksgiving with my wife, my daughter to visit my other daughter. So anyway, but in November, we went and did a meeting in Ohio and two people who were in wheelchairs got out of their wheelchairs in that meeting in Ohio. And the one woman, she was in an electric wheelchair, which I mean, to me that is an indication that it's worse than just standard wheelchair, right? Because with the standard one, you can at least push yourself over along if you need to. But anyway, she got out of her wheelchair and ran around the sanctuary and then when she finished that lap, she fell on her face, not because she fell, but she, as we say, hugely. She fell on her face, bowed down and was weeping and her husband stood there weeping because his wife had gotten out of this wheelchair. Okay. So where was this? This was in Ohio. In Ohio. Well, I have to ask you why was she in a wheelchair? Can you give us those details? Because I think interesting. Yeah, she had a form of a blood cancer. And she also had massive neuropathy and just pain in her bones if she tried to walk. So anyway, it was a kind of a complex healing. I probably spent, I don't know, 30 or 40 minutes praying with her, but anyway, that was the end result. And, you know, everybody, she just sort of vaulted out of the chair and started running. So nobody even had time to grab their phones. Somebody did actually have a phone in their hand, so we got some video of her running, but it's not a complete and total video from moment of vaulting out of the chair until moment of falling on her face. But anyway, we posted it on in my God is not a theory group on Facebook. And obviously it had a big impact on people seeing these sort of things are still going on. And they are. And there's nothing contrived or made up about. And he just was what it was. There was another woman who was in a standard wheelchair. And I can't remember what her situation was at this point. I sometimes I just see so many people I can't remember them all. But what I remember is it wasn't anything like a blood cancer. It was something, you know, you would say in the scheme of things somehow less serious. But anyway, she got up and walked around and so that was another one. Do you, you know, when I hear about a woman having blood cancer, neuropathy and this kind of stuff, I always think I wish I could hear from a doctor afterward. I know you've been making an effort to follow up on this because that's where it gets fascinating for people who just say, oh, I don't know what to think. When you get a doctor to say, we have no explanation for how you can. I'm just wondering if you or somebody or this woman and her family are following up because this is big stuff. Yeah, so this woman I actually am going to talk with her about that. But what most listeners wouldn't understand at all because they've never been in this situation is many people who come to meetings like this, they either don't have good pre medical history or they don't have good post medical history. And you actually need both to document something fully to medical standards. So they either show up and they didn't go to the doctor, but they know they're a mess. And they might be in a wheelchair, or whatever, it doesn't even need to be a wheelchair. It's just whatever their condition is. And then afterward, they might go to the doctor, but there's no prehistory in another times. They have plenty of prehistory they get healed, but then they don't go and get a confirmation. They just know they're fine and they go about their life as it was. And I think this is part of why when Jesus healed people, he would say, go show yourself to the priest. That was the equivalent of getting medical documentation. But having said all.
The Eric Metaxas Show
"blood cancer" Discussed on The Eric Metaxas Show
"Been happening? You mentioned something about angels and Costa Rica. I love this stuff, so what's cooking? Well, let's start in November. November was a really busy month. I was only home four days, although admittedly, 5 of the missing days were because I went to Texas for Thanksgiving with my wife, my daughter to visit my other daughter. So anyway, but in November, we went and did a meeting in Ohio and two people who were in wheelchairs got out of their wheelchairs in that meeting in Ohio. And the one woman, she was in an electric wheelchair, which I mean, to me that is an indication that it's worse than just standard wheelchair, right? Because with a scanner when you can at least push yourself over along if you need to. But anyway, she got out of her wheelchair and ran around the sanctuary and then when she finished that lap, she fell on her face, not because she fell, but she, as we say, hugely. She fell on her face, bowed down and was weeping and her husband stood there weeping because his wife had gotten out of this wheelchair. Okay. So where was this? This was in Ohio. In Ohio. Well, I have to ask you why was she in a wheelchair? Can you give us those details? Because I think interesting. Yeah, she had a form of a blood cancer. And she also had massive neuropathy and just pain in her bones if she tried to walk. So anyway, it was a kind of a complex healing. I probably spent, I don't know, 30 or 40 minutes praying with her, but anyway, that was the end result. And, you know, everybody, she just sort of vaulted out of the chair and started running. So nobody even had time to grab their phones. Somebody did actually have a phone in their hand, so we got some video of her running, but it's not a complete and total video from moment of vaulting out of the chair until moment of falling on her face. But anyway, we posted it on in my God is not a theory group on Facebook. And obviously it had a big impact on people seeing these sort of things are still going on. And they are. And there's nothing contrived or made up about. And he just was what it was. There was another woman who was in a standard wheelchair. And I can't remember what her situation was at this point. I sometimes I just see so many people I can't remember them all. But what I remember is it wasn't anything like a blood cancer. It was something, you know, you would say in the scheme of things somehow less serious. But anyway, she got up and walked around and so that was another one. Do you, you know, when I hear about a woman having blood cancer, neuropathy and this kind of stuff, I always think I wish I could hear from a doctor afterward. I know you've been making an effort to follow up on this because that's where it gets fascinating for people who just say, oh, I don't know what to think. When you get a doctor to say, we have no explanation for how you can. I'm just wondering if you or somebody or this woman and her family are following up because this is big stuff. Yeah, so this woman I actually am going to talk with her about that. But what most listeners wouldn't understand at all because they've never been in this situation is many people who come to meetings like this, they either don't have good pre medical history or they don't have good post medical history. And you actually need both to document something fully to medical standards. So they either show up and they didn't go to the doctor, but they know they're a mess. And they might be in a wheelchair, or whatever, it doesn't even need to be a wheelchair. It's just whatever their condition is. And then afterward, they might go to the doctor, but there's no prehistory in another times. They have plenty of prehistory. They get healed, but then they don't go and get a confirmation. They just know they're fine and they go about their life as it was. And I think this is part of why when Jesus healed people, he would say, go show yourself to the priest. That was the equivalent of getting medical documentation. But having said all.
The Eric Metaxas Show
"blood cancer" Discussed on The Eric Metaxas Show
"You're traveling all kinds of places and you pray for people and stuff happens. There are a lot of people that don't believe in the miraculous, and I would think if they would hang out with you, that would go away very quickly because you have a gift from God where you pray for people and stuff happens. And I grew up in a world where that never happened. And I think the people need to know God is alive, and it doesn't mean he's going to answer our prayers just because we want him to, but he does. And he can, and we need to know that. So you where have you been recently and what's been happening? You mentioned something about angels and Costa Rica. I love this stuff, so what's cooking? Well, let's start in November. November was a really busy month. I was only home four days, although admittedly, 5 of the missing days were because I went to Texas for Thanksgiving with my wife, my daughter to visit my other daughter. So anyway, but in November, we went and did a meeting in Ohio and two people who were in wheelchairs got out of their wheelchairs in that meeting in Ohio. And the one woman, she was in an electric wheelchair, which I mean, to me that is an indication that it's worse than just standard wheelchair, right? Because with a scanner when you can at least push yourself over along if you need to. But anyway, she got out of her wheelchair and ran around the sanctuary and then when she finished that lap, she fell on her face, not because she fell, but she, as we say, hugely. She fell on her face, bowed down and was weeping and her husband stood there weeping because his wife had gotten out of this
AP News Radio
Watch Live: Colin Powell's funeral held at Washington's National Cathedral
"Former diplomat Colin Powell will be remembered by family and friends at a funeral today at the Washington national cathedral Paul rose from humble beginnings to become the first black chairman of the joint chiefs of staff and later served as the first black secretary of state he'll be eulogized by Madeleine Albright who preceded him as the nation's top diplomat Richard Armitage who was deputy secretary under pol and pol son Michael Powell died two and a half weeks ago of complications of Colbert nineteen at the age of eighty four he had been vaccinated against the corona virus but his family says his immune system had been compromised by multiple myeloma a blood cancer for which he had been undergoing treatment my
"blood cancer" Discussed on WCPT 820
"A break about this tragedy on the set Baldwin fired a prop gun on the set of the movie rust that killed one person and injured another We were just saying I mean yeah we were saying the footage is out Baldwin's crying and obviously But John Erik hexam and we were saying Brandon Lee they were both also prop guns and I wasn't even aware that they shoot anything but blanks I didn't either But I guess they would Travis you said something comes out which is a blast comes out The glass comes out Yeah Hexam was the first one that this happened to me and this was in the 80s and it was a scene where he was Russian roulette and he picked up the prop gun and held it to his head and pulled the trigger There's a blast and just charges a cotton and when it's up right up against your head that causes the perfected that by now is that it also happened to Jason Lee you were saying Excuse me But this sounds like it wasn't even up a close against the director and the DP I read projectile Yeah So I don't know what happens It's clearly an accident I think I mean it's just awful For two people to be struck by it something had to have been just Right I'm gonna guess on cue because alcohol went a liberal right wing is already being awful about it Blaming him I'm just gonna I'm just gonna do it No were you surprised Well I guess we shouldn't be at how fast the right used Colin Powell's death to jump on anti vax stuff Not at all We were just saying that absolutely Absolutely And the misinformation Yes Yeah As we keep saying Colin didn't die because he was vaccinated He died because you weren't Step Yeah That's exactly it He was 84 years old He had had prostate cancer He had that the blood cancer And Parkinson's he was had you know a whole he was very vulnerable and he had scheduled his booster but he was already sick And it's like an Angela again the blood cancer multiple myeloma is a cancer of the immune cells And the treatment for it further it decreases your immunity So yep Yeah So if we were all vaccinated like we could be We'll probably be alive Thank you Thank you 29 minutes after the hour Fridays with fra Angelo Stephanie with her show You are listening to 8 20 Here's the latest Chicago traffic update 80 94 east traffic is slow from Burnham avid with Lansing to call you about avenue the trip time for the patient Ford freeway to the Indiana toll road is 16 minutes westbound 14 west belly on ramp from South Park about its closed crews are trimming the trees there Asia Ford freeway inbound traffic hitting the brakes the steel bridge to a 115 there is a crash passed a 130th ride shoulder 16 minutes 80 94 to the verge Inbound Kennedy 28 minutes so hair to downtown up on 19th As an hour 35 minutes from three 90 I found 25 Steven said 27 minutes from the veterans memorial You saw the Lake short drive to the cast of county line Ryan from dotty 50 downs out 13 minutes That's traffic.
AP News Radio
Powell's age and cancer bout left him vulnerable to COVID
"Colin Powell's death from covert nineteen complications despite being fully vaccinated highlights the continued risk too many Americans until more people are vaccinated Powell had been treated for multiple myeloma a blood cancer that hurts the body's ability to fight infections people with weakened immune systems from illnesses like cancer don't always get the same level of protection for vaccinations as healthier people age also plays a role with the CDC tracking dips in protection among older Americans who were among the first vaccinated how old was eighty four and it's unclear whether he received a covert nineteen vaccine booster experts are again stressing widespread vaccination is the key to helping protect the nation's most vulnerable Sager mag ani Washington
Your Grandparents Did What?
"blood cancer" Discussed on Your Grandparents Did What?
"Month. Okay where you could drink. Sheep buren or rabbit. Blood cancer okay. They also relied on rituals like circling spots of pregnant wolf pissed on okay so obviously a big part of middle ages in birth role. That is the catholic church. Okay a similar hands. A fuck the catholic church in gender statement. Fuck does motherfuckers. Yes a feels like all the time. More and more information comes out about why their garbage people were your garbage having so so The catholic church viewed procreation as an essential end of marriage and the sole purpose of sex was Was means to conceive children so anything outside of actively trying to have a child was considered like sinful so you weren't allowed to have sex for pleasure now. Were supposed to that sucks so going to get wine like waiting for marriage especially in these situations like a good idea to take care of yourself. Take care of your kids whenever ira i mean. It's not right. But i understand. Why but like winter marriage. Yeah that's what i mean. You can't be just fucking now. I guess on like what's the okay. So pope gregory. The ninth declared in the early thirteenth century that marriage contract contracted by parties intending to avoid having offspring or considered no saint on pope gregory. The ninth declared that in the early thirteenth century that marriage and contracted by parties intending to avoid having children. Were considered to be null so basically if you didn't plan having children you weren't actually married because that's the sole purpose of marriage. Oh my and the catholic church deemed birth control immoral obviously in one nine century. Text a quote a woman who has taken a magic potion however many times she is otherwise. Become pregnant giving birth month must recognize herself to be guilty of homicide. Oh god literally have like fourteen children. I just can't have fifteen children and you are considered and if you take something for an abortion if you take something from birth control either orcas. Wow i mean the the things are both right. Yeah there probably wasn't. I mean god someone they were doing guest so yes nonspecific anyways so man this is. This is all the bar starts. I'll get back to some more or less number on. This of course didn't stop efforts to prevent unintended pregnancies. And in some cases of birth control and abortion methods failed families would refer resort to infanticide. Yeah a lot of killing their baby. Yeah i mean. I mean because like i literally cannot imagine that but i also am like in live in central place of like well. If i had another kid i can take. I've had another kid. I could take care of la like you could just have to take care of it or have the means to put up for adoption family means to take care of it but if everybody you knew over their head everybody you knew was dying from all of the millions legs. We talked about all of the like have outside of wedlock. And whoever your on by because you were the mistress whatever and i have no support woman you can't get a draft milkmaid and like the lord of the manor. Whatever is yeah totally. I mean it may have been like the like highly decided like sympathetic. Saying yes you child because otherwise it would have starved to death or dive like a meaningful ways. Terrible so Pope innocent..
Talk Radio 1190 KFXR
"blood cancer" Discussed on Talk Radio 1190 KFXR
"RC arthritis treatment. Drugs now known to be responsible for heart problems can certainly on the front line of that and talks about that, with a really credible angle that you want to hear a good day health show dot com Also in this current podcasters The discussion about new high tech equipment that can has in his office. He described it any good cardiologist to have all of this high tech equipment. They don't often because it is expensive. By definition. It's a very important thing, though, to get the latest. If you really want to know what's going on in your body. That's why I like sending people they can because not only does he have The intellectual tools, but he has the physical tools to go through your body and figure out what the heck is going on. Or if anything is going. Maybe nothing got nothing to worry about. It's good to have peace of mind. You get that from visiting with Ken. Again. The number of the offices 35 to 735 1400 the way also and this current podcast can as his weekly shot at recreational marijuana use. And it's always Ali. Good ideas focused on your good health and well being. Get the podcast that good day health show dot com. Um I was were the whole business of exercises such a important threat to our conversations here every week and now another good reason for you to be focused on what you're doing. With your body and how it affects every thing. It isn't just the muscles that benefit but you've got this study on and who would have thought, frankly connecting the Dutch. The body is so Connected that if you are exercising well, it will have an impact on the possibilities of you getting colorectal cancer or not right? You you have pointed out in the past dug about how it's amazing how there are certain friends each week and I am amazed this week. How much In the extra medical journals. Information there is about exercise this week is amazing. And here you have, as you say, unexpected in the Journal of Clinical Ecology, this good news That walking and other light workouts may help to extend the survival time of people with advanced colorectal cancer advanced colorectal cancer patients. Doug, who perform low intensity exercise four or more hours a week, they have close to a 20% reduction in cancer or death. Yeah, well, that's very, very significant. And is this something new? Do you think this has been brewing? Do you think this has been on the back burner removed to the front burner now specked it but never proven. Mhm. Really? All right. Well, listen, here's something else when it comes to cancer department, blood cancer and how you get it. That's always been a mystery to me. How do you get things like Blood cancer..
Coach's Corner with Paul Ybarra
"blood cancer" Discussed on Coach's Corner with Paul Ybarra
"Nineteen ninety five nineteen ninety six I had an issue a blood. And i have a rare blood. Cancer and the doctors Found it. Because i have passed out in my parents home and is to kind a blood cancer that they find in older older adults and the doctors. All you're going to have to do this and you're going to have to do that. And so all of these remedies now. I'm gonna fasttrack. I've been on thirteen different forms of chemotherapy for this blood. Cancer anti reminds me of the woman with the issue of blight. Because she was going to all of these physicians and all of these physicians..
Z Morning Zoo
Mark Hoppus Reveals He’s Battling an Aggressive Form of Lymphoma
"From blink. 1. 82 was on twitch on Tuesday and revealed that he was diagnosed in late April with stage for a diffuse large B cell lymphoma. This is cancer. We knew yet cancer. He talked about the type of cancer. He has its blood cancer, he says. The taxes white blood cells is my blood's trying to kill me now, if you want good news. His mom had the exact same type of cancer and beat it. She also beat breast cancer twice so that mark that gene and is in him. Someone did. Um, he described chemotherapies in the first round, felt like being an electrocuted zombie. By the third round, he felt nauseous and sick. Um, he had a test done to determine the effects of the chemo. But there isn't an update. Yet he is optimistic and said, We're beating this cancer. It's just a matter of time. So staying optimistic. So
The Gee and Ursula Show
Chemical Linked to Cancer Detected in Dozens of Popular Sunscreens
"School kids, because right now the workforce desperately needs them. What's in your son's grain test by Val ashore in online pharmacy and lab show dozens of popular sunscreens and after Sun products contain a chemical tied to blood cancers. Benzene, a known carcinogen was found in 27% of this phrase and lotions. Test it That includes products sold by Neutrogena, Banana Boat and CVS. The problem with benzene is it can cause leukemia, anemia, things like this, CBS chief medical correspondent John Luke Luke says. One of the things the FDA will look into is how the chemical is getting into the
How COVID-19 has forced cancer patients and medics to juggle deadly trade-off
"Covid nineteen has affected cancer care in all countries rich and poor. Say what should the advice be to cancer patients who still need diagnosing treatment and potentially a coronavirus vaccine to to get some answers and to highlight how health authorities have been ensuring continuity of care. I've been speaking to dr andre bowie from the world health organizations department of noncommunicable diseases in geneva the impact of covid on cancer care profound because it has impacted all dimensions of cancer control from diagnosis to survivorship care and in that regard it has been a high impact and unfortunately very challenging time for the most vulnerable cancer patient seven this is worldwide as it in rich and poor countries. This impact in both high income countries and in some countries is that the case that health authorities have scaled back their cancer care after reports that covid nineteen outcomes are significantly worse among patients with cancer. Most governments are avoiding this concept of. Let's reduce cancer care because we know cancer is a time sensitive disease if we in fact delay cancer care either because of a government order or because of patient choice or because of the situation in team the consequences can be detrimental and for this reason. We've seen governments spun favorably to the extent that they are encouraging cancer patients to pursue care right. So let's put ourselves in a patient shoes a cancer patients shoes so they should carry on going to the hospital even though they might have heard somewhere that if they catch kobe they have a greater chance of being at risk. Is that right. That is the first starting point. As you rightly point out is the understanding bed. Some cancer patients are at higher risk for covid related disability or death if they can track the virus but because it has to do with immunosuppression the exact mechanism for which the viruses causing this increased risk of death for the cancer population. We are still trying to understand from disease perspective but one of the primary drivers is weakened immune system and the likelihood that the virus will take a greater hold spread more rapidly within the body and by extend to cause greater damage. That is the hypothesis but we are also trying to understand which cancer patients are at greatest risk is not all cancer. Patients are experiencing you potential harm of covid and cancer to the same extent. For example you've noted at some cancer patients that have what we call blood cancers or human to logic cancers are those that are experiencing grizz as compared to solid or the oregon based cancers like breast colorectal that may be lower risk but the exact likelihood that each cancer type incurs greater risk is something that again. We don't have a clear understanding because the data are still not well available for us to understand who is at greatest risk. The general message though is we know as a general group that cancer patients are experiencing greater disability and death from covid and because of this there is a tradeoff at many cancer. Patients are making sometimes in isolation but importantly in discussion with their healthcare provider. Understand what is it the right course of action for treatment.
The Bio Report
Bringing Innovation to Cell and Gene Therapy Manufacturing
"Farland. Thanks for joining us. Please join me. We're going to talk about or a biotech selling gene manufacturing and the company's efforts to use its platform to bring scouts to the manufacturing of selling gene therapies. Perhaps we can begin with the problem. You're trying to address. How gene and cell therapy is generally manufacturer today and what limitations do existing processes place on access and growth of the market. So i think Selling gene therapies are manufactured in a very similar way as when i scuffles in academic laboratories so that is very manual cell-culture prices which involves quite a lot of people Manley moving cells around the lab genetically modifying them dana cell culture expansion purification and really as you move towards the clinic what The major thing that happens is the those labs academic labs get tun into. Gnp manufacturing sweets where everyone scanned up. Sorry not any of the original problems with being highly money A manual prices in very labor intensive. But then you put on top of that. All of the Extra cleanliness requirements to jam manufacturing. A new end up with really expensive manufacturing prices. That require lots of people. Lots of very high school people actually and also a lot of spice space you need of the amount of Manufacturing facility need to produce a single device is very large. And what that means. Is that if you were to mention. The largest jam. Pay manufacturing site that you could ever imagine struggled to produce more than thousand isis pierre site. That's that's a major issue is selling therapy. Looks to move beyond our initial successes with the coffee therapies full for blood cancers and as we move forward. We're moving towards some really large indications where it's not going to be a case to just produced a fee thousand doses of therapy wigan each produce tens of thousands thousands of doses a moment as it stands. This is physically impossible. It can actually be done. There's no papal The space required is is mind boggling. How much of a bottleneck does manufacturing. The growth of these technologies is commercial products. Yeah this is the major concern. I think a lot of paper looking around investments In this space and they won young startup to have a clear To manufacturing scale and the reason for that is they've seen the struggles of the early entrance into the into the space and it's quite clear the you know the the there. All potential kills under development in very early startups. We may be in a situation. Where unless we get we get a grip of this manufacturing issue. Some of those early startups might stop not to get funded as people start to wonder can have make return on investment in in products or a biotech has developed a manufacturing platform for sale gene therapies. What is the platform consists of. So we've we've gone to some length start with the design for scaled up manufacturing. So how would you manufacture hundred thousand ices back engineered to a single unit on a lab bench and may shoal the pricing unit we designed which intensifies manufacturing automates manufacturing can still be used in an academic lab. So you can still do. You'll preclinical what the amount studies on a on a single already by pricing unit. But the real trick is is the the system is being designed to scale basic level. We've put a load of effort incident. Intensification of the volume. The physical volume needed today. This kind of process and we've come up with some really a novel engineering solutions. Which means that we can stack units horizontally and vertically. They're about the size of a microwave. And because we've brought in the stock ability. What you can do is you can stop envisaging. Scallop of your manufacturing in quite a small area getting to really high three putts. How does this change the manufacturing
AP News Radio
Tom Brokaw says he's retiring from NBC News after 55 years
"Hi Mike Rossi a reporting Tom Brokaw says he's retiring from NBC news Tom Brokaw of NBC news says he's retiring from television the eighty year old Brokaw who anchored NBC nightly news from nineteen eighty two to two thousand four says he plans to continue writing books and articles Procol last appeared on air on MSNBC's morning Joe on December thirtieth in two thousand seven Brokaw reflected on his arrival at NBC news after just two years on local TV in the Brzeska arrive in California working for NBC in nineteen fifty six just four years off the Great Plains working class families and small town Brokaw was with NBC news for fifty five years in twenty thirteen roll call was diagnosed with multiple myeloma and curable blood cancer that affects the bone marrow hi Mike Rossio
Living Healthy Podcast
Dr. Richard A. Van Etten: Cancer
"Please welcome to the show Dr Rick van how you doing. Thank you very much Andrew and Brittany I greatly appreciate the opportunity to be able to come and talk to your talk your listeners today. Yeah. Well, thank you for taking the time out of your busy schedule to talk to us. So we're GONNA be talking about obviously cancer and how you can prevent cancer do your best to prevent it. But as I mentioned in the Intro, most likely someone knows someone who's had cancer or they've had cancer themselves even it's pretty it seems like it's touches a lot of people but can you kind of tell me how many people does cancer impact on a yearly basis? Well. Thank you for the question Andrew. The lifetime risk of getting cancer is approaching thirty eight or thirty, nine percent. So more than one in three Americans will get cancer during their lifetime. So that explains what you said that basically almost everybody is either been personally. Involved with cancer knows a close family member or a loved one that's been stricken by cancer. So some of the statistics nationwide in the United States, there's about one point seven million people diagnosed each year with cancer. And they'll be about unfortunately six hundred thousand Americans will die every year of cancer. Here in Orange County it's interesting that cancer has overtaken cart diseases, the number one killer, and as soon gonNA happen nationwide. So a very very. Prevalent disease what kind of has led to what's led to that trajectory? Why is that happening? Well, actually the the the death rate from cancer has been falling and it's been falling significantly over the past fifteen or twenty years, which is a success basically for the research that's gone into it through the National Cancer Institute and other mechanisms. But the fact that cancer is now the number one killer has actually also reflected progress in cardiovascular disease. So doing which used to be the number one killer. So we're doing a better job at preventing. Heart disease through the things that you know about treatment of the risk factors like high lipids, blood pressure, diabetes et CETERA. Right? Interesting. Okay. All right. So we got some work to do on the cancer and Kinda catch up. And, that generally, like I mentioned usually happens through education funding, which we'll talk about in a little bit What types of cancers are the most prevalent today? I know that you specialize are a believe in like blood cancers by what are the most prevalent that people run into so we can talk both about incidents, which is the new diagnosis that we have each year and prevalence, which is the number of people living with the disease at any given time. But the top four in both categories are pretty similar. So there's breast cancer which obviously predominantly affects women but also can affect men. Then there's lung cancer there's prostate cancer which obviously is a male cancer and the last one is colorectal cancer. Those are the big four. Close on their heels are diseases like skin cancer and melanoma that's particularly relevant for Orange County where we have two hundred and eight, hundred, ninety days per year rate. And after that come some blood cancers that I specialize in, which is mainly things like leukemia lymphoma and Myeloma Okay. What kind of leads to these types of cancers occurring out of those top four that you mentioned, what? What's the biggest contributor to people getting? Is it? Is it just genetics you got bad genes or something in your lifestyle or in your the world around you I guess causing it. So they're. Probably, equal contributions both from genetics and from lifestyle. Okay. When I say genetics I mean the cancer is principally in the opinion of a lot of primarily a genetic disease in the cancer cells have acquired mutations that contribute to their malignant or cancerous phenotype, their ability to grow and attack the body. Most of those mutations are acquired in other words they happened just within the cancer cell and they're not inherited. So you don't get them from your mother or your father. Now there are exceptions there are well defined cancer susceptibility syndromes the most the one that may be most familiar to your listeners is the bracket jeans Brca which segregating families particularly people, of Ashkenazi, Jewish descent that are inherited either from your mother or your father, and greatly increase your risk for developing breast cancer or ovarian cancer so that the risk for women who doesn't ever bracken gene mutation is about one about eleven percent or one in nine during your lifetime. If you inherit one of these genes, it's virtually almost everybody will get breast cancer ninety percent risk over your lifetime. So, this cancer susceptibility syndromes are very important the need. For instance when there's a new cancer diagnosis, you need to take a careful family history and in some cases be referred to a genetic counselor to determine whether testing family members is indicated. Yeah. Well, that's interesting that you bring that up because my wife actually we went through that process, and so she was found her mother had breast cancer and through that process they found out, she had the bracket gene Brac to and then and so my wife decided because they kind of give you choice like do you want to get screened? Do you not like you kind of have? Do you want to know more or or like not and stay naive to it I guess and so what I've discovered, we went through it and is interesting out of the split my wife got it and her sister didn't so the fifty, fifty there and. It. Seems like. It's I think my opinion is it's good to know because now they're just more aggressively screening her and is that typically the case when you find out about something like that, you're more your screened even more regularly than the average person should be. That's right. A change basically changes the surveillance. In it not to make it more complicated. But there are some genes like the broncos where the penetrates which means that the chance of actually getting breast cancer. If you have the have, the mutation is very high I think there it's pretty straightforward to decide whether to get screened. Right. There are other mutations that can be inherited that don't increase the risk that much increase it above the background, but it's not nearly as high and there it's more complicated to try to decide what to do about that. But. My advice to your listeners is to seek the advice of a NCI cancer center in a a qualified genetic counselor. Those are the people best qualified to help guide you through that decision making process right? Right. When you're going through like you said they ramp up the screening process if you had the genetic mutation but how does how did we get to discovering these genetic mutations I? It sounds like you kind of have somewhat of a background like you discovered or help discover this protein that was causing leukemia right and. How does that process even work? How do we make these discoveries? How do you make these? Discovery I was involved in is one of these acquired mutations not inherited, but it came about from studies done many many years ago actually nineteen sixty that showed that patients with this particular type of leukemia had an abnormal chromosome in their blood cells. And when to make a very long story short when that was tracked down, it was shown that the chromosome was actually an a Barrett. That was acquired in these cancer cells that lead to the expression of this abnormal protein. And that protein. Hasn't is an enzyme which means that it has a ability to catalyze chemical reactions. Okay and that particular reaction stimulated the growth of those blood cancer cells. So. That led a drug company, which is today is no artis to develop us a drug a small molecule inhibited the action of that protein. And that That drug which has the trade name GLIVEC revolutionized the treatment of that leukemia so that in the past everybody died of this leukemia, unless you had a bone marrow or stem cell transplant. Today everybody takes a drug likely. And most people go into remission and when they do, they have normal age adjusted life expectancy. That's example would that's Therapy likely that can do to cancer right? So does this all come from these discoveries? Does it come from just? Tons of data over decades like this one you're saying, it came from research started in the sixties and this didn't have until the early nineties. Is that right or wealth the the The structure of the protein was discovered. I'm saying Circa Nineteen, eighty-four which I got involved. The drug development efforts took place shortly thereafter I'm and the was FDA approved in two thousand one. So it's been on the market now for almost nineteen years I and there are many many other efforts in other cancers that are parallel parallel that. The thing that's happened today is because of our new technology and the genomics and the ability to determine, for instance, the genome sequence very quickly that's accelerated the progress that we can make. So what took forty years from sixty two to the drug being approved now can be done in a couple of years. Wow. Everything's happening much much faster. That's awesome. That's great news for those of US living right now.
Science Magazine Podcast
Fighting cancer with CRISPR
"Now we have staff writer Jennifer cousin Frankel. She wrote a story this week on Crisper and cancer immunotherapy to big ideas says mushed together for the first time in human patients. Hi Jennifer Hi. Thanks for having me sure. I said something scary. It's not every day that we get to say a something is a first. There's always a lot of pushback whenever we put it into a story or if it comes up in a research paper but this is some type of I. This is the first time that that researchers have reported on taking immune cells in this case the T. cells which we kind of think of as the soldiers of the immune in system that fight off infection using crisper to modify them together and then putting them back inside a human body and seeing what happens. It's that hasn't been done before. It hasn't been described before their trials that are going on. That are testing this and this is why we never put I in a headline exactly far to do was dive into the techniques. We're GonNa talk about cancer immunotherapy and then we're also going to talk about crisper. We need to kind of understand both of those things to understand what happened in this paper. This is a specific kind of cancer. Immunotherapy right yes. That's right so cancer. Immunotherapy is essentially trying being to harness the immune system to fight cancer. And it's something that's been really hot in the cancer field for the last several years in fact won the Nobel prize is just the other year. What this study is making use of is one technique in cancer? Immunotherapy that uses the T. cells and it tries to to sort of help. The t cells recognize tumor cells and then destroy them some of the problems that have come up as people have experimented with that. Were things like it. It doesn't really get into solid tumors and some other things. This is still a really new field and people are still working very hard to improve. Its success it's been pretty successful in blood cancers leukemia in lymphomas and there are two Cardi cell therapy's that companies have developed in that have been approved there are some additional additional hurdles in solid tumors. And it has been more difficult to consistently get the therapy to work in solid tumors solid tumors or things. Like brain tumor pancreatic host humor. Like I think yeah any tumor. That's kind of a solid mass as opposed to in the blood. That's the cancer immunotherapy side of things. Let's talk about the crisper side of things. Can you just tell us what crisper is. And then maybe we can talk about how. It's been used their politically or not so far. So crisper is another really hot area in biology Jay. It's a technology that essentially cuts DNA and then the DNA can kind of recombine in different ways it can be used in different settings to add genes or DNA to remove them. It depends but it can give a lot of flexibility around modifying DNA A and it's used in all different settings not just in medicine but strongly medicine is one area where there's been a lot of interest in using crisper because it's a way of modifying lying. The genome in this case crisper is used to modify immune cell so they took immune cells out of a patient and then use this gene editing technique to make changes to them. They had these three patients and what they did was they took out blood cells and then they modified those cells in the lab. They had to add in a gene gene. That was going to target a protein that was on the surface of their cancer cells. The other thing that they did was they used crisper to edit the genome such that they were knocking out three other genes and the genes that they chose they chose because they I hope they would make the T. cells even more powerful. They hope they would help them. Hang around longer in the body more effective against the tumors than they reintroduce introduce those cells. They gave them back in. That whole process takes several weeks. It takes four to six weeks to from the time you take the blood out to the time you put the cells back in. They had to go through a number of layers to make sure that they were really doing everything safely and carefully. So what were they worried about when they reintroduced these cells into the body. One one question was just you know with these cells even survive right. He just kind of disappear which has been a problem. In general with some genetically modified t cells it can be hard good for them to kind of thrive in the body and these these were cells that had been modified in several different ways. Then of course another question is are they going to cause harm MHM if they do survive and one particular concern with crisper. Is that when you go in to do this. Editing you can have these off off target effects. Were you accidentally cause modifications to other DNA. That you weren't aiming for there was concern that that could happen then of course that's changing other. DNA in the T.. Cells who knows what effects that might have on the patients so those are the big two questions and then also you know they probably wanted to know if the people would get better. Everyone of course hoped that that it would help. These patients get better at the same time. The trial was not really designed for efficacy it was too small and it was also also so new and so they made certain choices in the very specific details of the treatment. They offered that improved safety. There were certain things they did did to try and make it less likely that the immune system of the patients would react in a sort of dangerous way to the cells but in doing so that could potentially elite reduced. How effective the treatment is you know the target that they picked on the cancer cells? They pick that specific target because there had been a number of trials targeting doing that with traditional therapy so they knew was probably a pretty safe target. But it may be isn't the best target unfortunately and as you might expect from. I'm talking about it. The patients did not recover from their cancer. Because of this therapy. What were some of the other results of the experiment that we can talk about now so I would say the results were that for the time for which they've been followed? The treatment appeared safe so far. Nothing scary happened nothing. There were no showstoppers. They saw some off target effects. But those off target effects didn't seem to cause any obvious harm to the musicians in the cells that had the off target effects. The percentage of cells with those effects seemed to kind of fade out over time about the target effects like the changes made to the T.. Cells of these patients. Were those persistent in the body. One thing that I think was quite heartening. Is that these. He sells really stuck around in a way. That other t cells going after this particular target haven't in other published studies and so they've they've lasted so far up to nine months and they're continuing to follow these patients and also when they took out the cells over months which they did did they would take blood from the patients and then look at the sells again it could get them back and study them in the lab and those sales were targeting cancer in the lab now like you say in the patients. The benefits were definitely limited. There were three people treated one of those people has since died and in the other to their disease has progressed and they are getting other treatments. MHM so the effects were limited. You know it can be hard to kind of know how to understand that on the one hand this is just three patients and so we were very very sick. And so if we're thinking about what's going to be an effective treatment you need to treat more people to really know and then again you're thinking about this. First Time in people have focused on safety safety from your story from boats. It really seemed like that people in this field were saying this is a step. This is getting us over a really big hurdle. Yes I think it's a step and I think it's kind of layering on the use of crisper onto this other area of cell therapy that have gotten so much interest interest in generated so much excitement cancer but also still have a lot of room to improve and it's a way of saying can we make better use is other technology. What's expected to happen next more of the same thing? Are they going to try to infer different targets. One of the exciting things about this field right now. Is there so much happening. And people have so many he different ideas for what they could try and there are a lot of different theories and we don't really know what's going to pan out and what's not and so there are a lot of different. The group's thinking about different targets different cancers other diseases of course to apply crisper to their companies. That are involved. They're just a lot of different ways. You could go with this but right now. There are other trials that are recruiting patients for crisper modified t cells else and some people. I talked to said you know. There are surely going to be many more trials opening in parts result of this study. What kind of of regulatory oversight was there for this is there a body that governs crisper studies? There's not a body that's specific to crisper but there is as a group called the recombinant DNA Advisory Committee which is a a panel that has traditionally vetted the safety and ethics of different gene therapy trials funded by the US government or other other funders and so this went through the review of that committee. which is colloquially known as the rack of the and also so went through you know a lot of review of the National Institutes of health a lot of review from the US Food and Drug Administration? You know as you can imagine anything new. Where you're you're genetically commodifying cells to a degree? You have four earn away. You haven't before writing them into people you have to be careful and of course you know. Everyone has hopes for this therapy in the years ahead. And because of that you have to be so careful when you're starting out. The hopes of a lot of people were pinned on gene therapies. His and yeah you know some early problems. Really put a damper on the field for a long time. Yes if something really terrible happens not only is that obviously terrible for that individual it has these ripple effects across the field and so I think the people running this trial. We're thinking of both of those things as they designed and pursued the study. Thank you so much Jennifer. Thank
Morning News with Manda Factor and Gregg Hersholt
9/11 first responders may have increased risk for cancer
"A new study shows that nine eleven first responders are at a greater risk of developing leukemia the lead author from the I con school of medicine at Mount Sinai says the study is the first to show an increase in the incidence of cancer which may take years to develop after exposure the study found that those exposed to the toxins found at ground zero have a forty one percent higher risk of developing the blood cancer compared to the general
Healthcare Triage Podcast
CAR T-Cell Therapy and the Future of Cancer Treatment
"Today we're GONNA be talking to Cherie Virago professor of medicine and medical molecular genetics and also director of the stem cell program. I use school of Medicine. He Generals General's GonNa talk to us today about stem cell. Therapy and car T.. Therapy in particular which you may have heard in the news but before we get to that. Let's start with some basics first of all. Welcome to the program program thank you. Can you tell us in general what it means to be not only a professor of medicine but a professor of medical and molecular genetics so medical Michael Molecular Genetics. It's a very broad term It's it's really looking at the molecular basis of disease Not just inherited a disease but Many of the diseases have a molecular basis. Even if they're not directly inherited had he actually look get to the molecular basis. What kind of research technologies are you using? The biggest technology at the moment is Sequencing genes particularly in in terms of Chewers in my area sequencing can cell's genome to identify particular mutations. That could be targetable identifying mutations Sion's that in future could be Way We could design drugs perhaps decided Also there are ways of personalizing Medicine in a way Way We can identify Because not all cancer even the same kind of cancer is not all Homogeneous there's a lot of heterogeneity so if you can identify certain mutations in a person's at cancer cell you may be able to target that specifically perfect for that person's cancer as opposed to all the people with that kind of cancer. So how do you train to do this kind of work so in your career career how what did you do to get to this point. Well I guess there are various ways of getting there the way I got there. I trained actually in Australia Did all my hematology. Aw called you training in Australia. And then I did a PhD. That was more related to stem cell transplantation rather than molecular medicine at the time and then I moved to Ohio state where I stayed there for about six years on faculty and then the opportunity came to lead the transplant program. Ram At Indiana University. So I moved there in two thousand six. So we're talking about treating cancer. Is it all kinds of cancer or specific kinds of cancer. Turner accident well as a stem cell transplant. we're really focusing on hematological. Kansas blood cancers So leukemia multiple myeloma lymphoma. These are the ones that are amenable really to stem cell transplantation. You talk about what the differences are between those three short so It's really the cell of origin or the origin of the cancer so leukemia we're really talking about Cancers of blood stem cells the bone marrow in multiple myeloma. We're really talking about Cancer cells plasma cells which really part of the immune system in lymph falmouth with talking about cancer cells that are also part of the immune system that the less differentiated cells than the Coloma. So what what causes these. What makes someone developed one of those types of cancer? Well that's a really good question and we don't know all the the answers to that but It the it's silly as with other Kansas to I'll just blood cancers there are Hits in the genome of the the cans of the cells that turns them on to become cancerous essentially and so once they become cancerous. They just start growing multiplying without controls trolls. That the gist of it. Or Yeah. That's basically it they. They're able to multiply without control but they're also able to survive better They have a survival advantage compared to their normal counterparts talking about the history of treatment of those types of cancer. Like what do we do. And what are we. What are we got into now? And specifically of course what is stem cell therapy. Happy at the end. Yes so you know historically the we have been treating and we still the do treat These cancers with conventional cytotoxic agents these agents are essentially cellular toxins that cause DNA damage to the cells and as a result they The cells sells died and they because cancer cells tend to divide more frequently or more rapidly than normal cells and these conventional channel cytotoxic target the proliferating cells more than the Doman cells. So we're able to Mo- selectively kill cancer cells. But they are. They also affect normal cells as well as things have evolved We are now able to. We learn more about the genetics of the Kansas. His when now able to design drugs that particularly targets in pathways molecular pathways. That these cancer cells depend on so Treatment has become Less toxic to the to the patient in general so we're trying to target specifically just killing the cancer while not killing other other rapidly or any other kinda cells in the body. So what is then stem cell. Therapy like what. What's the difference between what skyping there and then going all the way to say? We're GONNA do a stem cell. Trance have so in some cases not all Kansas but some Kansas are also amenable to stem cell transplant therapy. And they're really too broadly. Speaking to approach is one where we use. The patient's own stem cells called tolerance stem cell transplantation. And where we use dona cells or allogeneic stem cell transplantation so with autologous transplantation plantation would really reverting back to the classic cytotoxic approach way we give very high doses of chemotherapy to Kill Oh as many cancer cells as possible. One of the side effects of this is that it will also cools a permanent damage to the bone marrow of people without stem cell support report. They would Essentially die of marrow failure so to collect stem cells. I there on stem cells assuming their stem cells not diseased. Then when you can give high dose. Chemotherapy give back stem cells and allow the marrow to recover so I have a couple questions there first of all. How do you get the stem cells? Out So stem cells live predominantly in the bone marrow But they do circulate the blood so you can either collect directly from the bone marrow but more commonly family today in the autologous approach we give growth factors which can move stem cells to circulate more in the blood and then we collect them. I'm by a process called a ferocious. Where basically they are collected a blood donor machine essentially that will collect them from the blood? How do you how do you how are you sure? You're not collecting cancer cells at the same time you do Some of these stem cell products will be contaminated but to some extent by cancer sells but it seems that most relapses after autologous transplantation occur not because of contamination. But because you really the the chemo a high dose chemotherapy that you've given has not killed the last cancer cell in the body. So how are you also assured that the stem cells are not. Can't where's the cancer come from. If it's not coming mm from stem cells as the simpsons or what about the sort of the the. He met a poetic stem cells. That give rise to the sherm tie. He met a point system. MM-HMM SO For example in multiple myeloma these inadequate ext themselves are not cancerous. Okay and in lymphomas Somali. They are not not cancerous. Can you just give us just a brief description of what the poetic system is so the Humana poetic system is essentially all blood forming cells and immune cells so the very primitive stem cells that give give rise to the humanitarian existent. They give rise to white cells red cells platelets as well as the components of the immune in systems such as B. Cells. T. Cells natural killer cells. We're just trying to figure out in my head and where it comes from. Because if if the are the white blood cells coming from the bone marrow in the stem cells though in development I it depends on the Canada Essentially for example if we take multiple well my Lama so the Within the immune system one cancer cell becomes Transform to become malignant and phones a clone in that clone of actually expands and has sub clones of its own and that's really the cancer but that's not arising from a in the actual stem cell of the very primitive stem cell that gives rise to all the blood forming cells in the Merrill.
'Bubble Boy' Disease Helped By Advances In Gene Therapy
"Sometimes rare diseases allow for scientists to pioneer bold, new ideas. That's been the case with a condition that affects fewer than a hundred babies a year in the US, those babies are born without a functioning immune system and the quest to cure them has led to advances in technique called gene therapy NPR's, Richard Harris reports the disease is called severe combined immunodeficiency or skid met Portia Stanford. Pediatrician says you might be familiar with it. It was made famous I guess in the mid seventies. When the bubble boy was described in in Documenta documentary. And I think he captured the imagination of a lot of people David Vetter spent most of his short life in a plastic bubble to protect him from infection. He died at the age of twelve things have come a long way since then all babies born in the United States are now screened for this. Edition and standard treatment a bone marrow transplant succeeds more than ninety percent of the time when it's done promptly yet. Skit remains a source of great interest to researchers. This is one of those diseases in which probably more doctors and scientists studying the disease than patients who have the disease in the nineteen nineties European scientists actually cured it in some patients. Using gene therapy this technique involves removing defective. Blood cells from a patient inserting, a new gene with the help of a virus? And then putting the cells back into the body, though cells than build up the patient's immune systems, Dr Donald Kohn at UCLA says at first it looked really good and initially twenty patients, they all had immune recovery. But over time five of them went to develop leukemia to scramble to figure out how to inject new genes into cells without triggering that blood cancer, and they're cautiously optimistic they've succeeded since then there have been gradual improvements in the technique the latest advance involving eight infant. Shows that a short dose of chemotherapy helped the new cells take root, the infants ended up with apparently healthy immune systems. I am thrilled to CDs. Outstanding results Eveline among Sasha at Saint Jude's Children's Research Hospital in Memphis is first author of a paper reporting these findings in the New England Journal of medicine to be able to see these babies in my clinic now as toddlers Israeli very rewarding they live normal lives. There are not any different from my daughter's today most children with skid who get a bone marrow transplant also need ongoing treatment, including lifetime injections of antibodies. Jennifer puck a pediatrician at UC San Francisco and a study collaborator says infants who got the newest gene therapy don't need that medication and they're growing. Normally they're getting cold like everybody else, and they take it over infection. So I would say that that is a cure. Of course, she adds that they'll be watched carefully for signs of leukemia and to see if the. Of the therapy are wearing off in her mind. The key is finding these children early through newborn screening before they start to get life threatening infections that had typically been the case. And now we're seeing happy bouncy little newborns. Just look perfectly normal. This is not only good news for those rare families the disease provides a good opportunity for all the scientists to develop even newer, gene therapy techniques, for example, instead of inserting a healthy, gene. Matt Portius at Stanford. His used a powerful gene editing technique called crisper to correct the genetic error in skid blood cells. It works with human cells in a dish. And this really sets the stage than for testing the approach in a clinical trial. Hopefully in the next twelve to eighteen months. All this makes the leukemia setback from the nineteen nineties feel like a fading memory Cohn at UCLA said for more than a decade. It seemed that the field was a dead end. But no more just nice to see. Another success for