35 Burst results for "Aspirin"
Jake Paul Wins Latest Boxing Match in First Round Against Ben Askren
"The fight last night. The trailer fight club is what Snoop Dog is calling it and I would literally I would play. Jake Paul knocks out An aspirin. Jake Paul is just that YouTube star who was like 15 million Instagram followers. Ben Aspirin is a former M M A fighter who I've never heard of before. And he made $500,000 for this fight against Jake Ball. $500,000. That's his biggest payday ever. And he's in his mid mid mid thirties like 35 36 something like that, right? Take Paul knocked about the first it was. I think it was 119 seconds under two minutes of the first round. I would play that we would play the play by play for you. Except it's nothing but F bombs. Take everything you think you think of her thought of in a boxing match and throw that the hell down out the window or down the toilet, flush it down the toilet. Snoop Dog and company are doing this broadcasters F bombs. There's profanity everywhere, so I wouldn't have. I think I'm gonna ask Anthony. You're James to try to try toe sensor that to get it on the air. We miss one and people get in trouble. All right, but people love
Going red for women and heart health, raising awareness
"Today is national Wear Red Day It's aimed at raising awareness of women's heart health. Cardiovascular disease is the number one killer of women in the U. S. And effects about 44 million people. CBS views. Senior medical correspondent Dr Terror in the ruler who's a cardiologists and a spokesperson for the American Heart Association, appeared on CBS this morning with more on women's heart health. If a woman arrives at the hospital, she's going to wait longer than a man to be seen for chest pain Less often, she's going to get aspirin or guideline directed medical therapy or diagnostic testing. This is a big problem. I have a lot of patients telling me my doctor told me I'm just anxious. I'm just stressed out when in fact they have a real problem. Alarming new survey by the Cleveland Clinic found coronavirus confront Could coronavirus concerns Rather are preventing some heart disease patients from going to the doctor?
DECLARE-ing Another Victory for Dapagliflozin
"Well hello and welcome to the i former x podcast where we explore the evidence that informs aleatory care pharmacy practice. This is stuart hanes the host of the i former x podcast in about a year ago we reviewed and discussed the data h f study which evaluated the benefits of the sodium glucose transporter two or s. l. t. two inhibitor. Adaptable flows in in patients with reduced ejection fraction. Heart failure even in patients without diabetes. And if you are not familiar with a data h f study. I strongly encourage you to read the original study. And the i former x commentary of course. The data regarding the use of the sglt two inhibitors to prevent cardiovascular events and to treat heart failure or quite compelling but can they also slow the progression of renal complications in patients with chronic kidney disease. Well i was excited to see the much anticipated data. Ck d. study published in the new england journal of medicine a few weeks ago. And i knew just the right people. I wanted to review this study for i former expert. Dr jennifer clements dr stephanie. Nitro jennifer and stephanie are no strangers to i former x. They are members of the i former x oriel board and have been frequent contributors over the years. That clements is clinical pharmacy. Specialist in diabetes transitions at spartanburg regional health. Care system in spartanburg south carolina indoctrinate grow is associate professor of pharmacy practice at the university of connecticut. Stephanie jennifer it's great to welcome you back on the i former x podcast. Thanks for the invitation stewart. Thank you for having us back so before we get started per usual. I'd like to get your thoughts on a patient case. A i think that is not unlike. What many of our listeners encounter in their practices and want to imagine. You're seeing k t a sixty one year old african american female in the primary care clinic today. The patient has a longstanding history of hypertension type two diabetes dyslipidemia and. She's morbidly obese. She also has osteoarthritis internees. She recently was diagnosed with chronic kidney disease in her primary care physician referred her to you to make certain quote. We are doing everything we can to protect your kidneys. According to her medical record katie has been prescribed lysenko pearl twenty milligrams twice daily resume astatine twenty milligrams daily metformin thousand twice daily and insulin Twenty it's bedtime and in addition over the counter. She takes aspirin eighty-one milligrams and naproxen sodium for arthritis pain. She currently weighs two hundred sixty four pounds of bmi forty point. Nine blood pressure today when thirty. Eight over seventy six and her most recent labs yesterday include a fasting glucose of eighty seven and a one c of six point seven percent. Sam crat nin of one point seven milligrams per deciliter and an estimated. Gfr of thirty seven seven potassium of four point seven. Ldl cholesterol fifty six hdl cholesterol. Forty eight triglycerides of one. Oh seven in addition. The patient had a timed urine protein tests performed and the album into creating ratio was three hundred fifty. So stephanie. Before we talk about the study that you reviewed in your i former x commentary. I'm wondering what's going through your mind in this case What are some of the key questions you ask this patient during the encounter and what additional apps if any might you want to obtain and is there any additional treatment options. Who'd be considering at this point to stewart. I would agree that. Kt really does mirror. Many of the patients that are encountered in clinical practice. And i think this case excites me because there are many opportunities for the pharmacists to intervene here and if we're going to utilize the ppc process. I would. I want to collect additional information from kt. for example. Does she smoke. How often is she using her naproxen. And at what dose. I'd also want to collect possible. Her a. one c. Blood pressure and serum craton and trends and we know how important it is to not evaluate labs in isolation so seeing her patterns would provide additional insight or care planning. It's really important to know. Kt's renal function is stable or if it's consistently fluctuating as this information would help our assessment of how we can manage. Her current metformin does since her egfr is approaching the cutoff for continue at minimum. She needed both reduction. And also story the for thinking about the potential use of sglt two inhibitors for katie ensuring that arena function is stable. What help us feel more comfortable recommending. Its use since we know that there have been reports of a two kidney injury and volume depletion upon initiation of these drugs. I don't want wanna collect a bit more information about her. Lifestyle habits including a general understanding of her dietary choices notably her sodium and protein intake and see if she is engaging in any physical activity given her need when the patient and osteoarthritis. I'd also wanna know her insurance provider and learn if she's burdened by any of the cost of her current medications in case we want to add anything in the future cd management perspective. I'm really happy to see that. She's on than a pro because she has albumin. Urea but further management is needed to help delay rano progression and when we think of good. Ck d. management. We need to consider it. I optimizing her glycemic control which looks really good for. Kt at this point and also painting and maintaining a blood pressure will have less than one thirty over eighty if we can do that safely
‘I feel betrayed’ — Ken Langone blasts Trump and Capitol rioters, vows to support Biden
"Katie kramer today on our podcast. Ken langone in an extended interview. The famed investor and home depot co-founder weighs in on crisis in the capital feel. the trade. Last wednesday was disgraced. It should never have happened in this country. And if it doesn't break every america's heart something's wrong it breaks my heart. In spite of civil unrest he certain about one thing or i care about is one thing january twentieth. Biden's go to be sworn in as president. And i'm going to work my ass off anyway i can. If he's a great suggestion. President we all went. Landon speaks out as the patron of a major new york hospital and a product to the city's public schools. What are we going to start as a nation to realize double to be eaten alive by our foreign competitors for one basic reason. Public education in america is disaster. And i've said years ago. What are we gonna fit. And he's got a message for the one percent we need to put. The greater good of the country. Had a philosophical beliefs are on our own aspirin. You want to spend more money. You know what i'm saying is let's pay more taxes. Everybody i know that's a feels the same way. It's
Kim Kardashian and Kanye West discussing divorce
"At the end of kim. Yea oh my gosh. Welcome to daily problems. Get right into the story. Everyone is talking about this morning. Is kim divorcing konya. Here's what we know you guys a source tells us they're trying to work through things in marriage. Counseling divorce has been discussed. But kim really wants the relationship to work. We've been hearing. They've been living separately for months. However another source says. Kim will always care for connie but it's over between them. We're told kim is hesitant to file for divorce. Because she wants to make sure she's making the right decision for their kids. Any news reached out to their reps for comment. It's a lot to dissect. I mean what's your first thoughts when you heard this justin. I feel this has been going on for quite some time. I feel like the writing has kind of been on the wall that these two are taking some time away from one another and this didn't come as a shock to me because from what i know of came in. They were inseparable for six years when he came to red carpets. When it came to family things. Once i started seeing on you pop up kinda sporadically throughout things. Not showing up at christmas and not being on the aspirin trip. I feel like i kinda sorta felt like these two are taking time apart. Yeah and i revealing that you know. She had an abortion. That was very telling that they were out of part where they definitely did. Not win. didn't have almost ad. Sorry you're right. Sorry about north am sorry. Let me correct myself. Yes almost had an abortion. And i felt like it was just yeah. We could just foresee that there were problems. I just didn't know it got at this point. Is there any way you think that they could actually save this marriage. Do you think they even want to know. I feel like i feel like this marriage. At this point. I feel like they've been doing this. Limbo for a very very long time. I think they have tried their hardest to make it work. In every single capacity try different versions of what marriage looks like. And i think at this point they love each other. They have respect for one another. They obviously have four children that they are very much devoted to. I think the romantic involvement between the two of them has just fizzled out. And i just think that. Kim has really tried as hard as you possibly could. And as well as conway and i don't think this is going to be one of those breakups turns into this bitter mass and turns into this tabloid food that everyone wants it to be. I think it's going to be these people. They've had four kids. They've tried for six years to make it work. It doesn't work. They're still going to be in each other's lives in a creative way. They're always gonna be there for one another and having involvement off. But i just i don't i. Don't foresee the two of them reconciling in a way that's like you're my husband and my wife. I just don't see that for them.
"aspirin" Discussed on Stuff You Should Know
"What chemical processes at work. Yeah we just know that it does work in this way and we also know from all these studies that it has this side effect and it might affect this group more in this way than other groups Apparently aspirin has the largest chemical database of any compound anywhere I don't know if that's true or not. I read it in a croatian brand profile of aspirin By it's a great. Knock your socks off kind of fact if you ask me yeah they. They eventually did learn didn't they. They definitely did learn that. It does work. And exactly how i guess. Yeah that is kind of one of those rare examples of how we did figure it out. Isn't it. I think so In the late sixties and early seventies And they were using a building off the work of harry collier john von priscilla piper They figured out that the was a substance in the body. It's weird. They have figured it out in a roundabout way. 'cause they figured out. What the substance was that actually causes inflammation than in the body which is The release of prostaglandin and they figured out that insides actually stop this from happening an aspirin inside like we said and so in a roundabout way. They ended up figuring out how it worked. Yeah and so. Prostaglandins are like a whole class of hormones that are produced at the site of like an injury or an illness to help your immune response like inflammation pain all sorts of stuff that basically says like this needs to be taken care of in the. We need to get some some immune response here as fast as possible and so aspirin blocks prostaglandins from being released By enzymes called cyclo oxygen. As which kind of kick off the production of prostate gland. And they figure this out. This is how it works. This is how the anti inflammatory process works. And it's kind of a. It was a big enough deal that john wayne received the nobel prize for nine thousand nine hundred eighty two for medicine. Yeah and they also figured out and this is kind of key with aspirin Not only does it Does that enzyme inhibit that release but it kind of can do it permanently. Which is what separates aspirin from What's one the other one. The big one Advil advil yes. I'm blanking 'cause. I never take any of that stuff really. I'm an advil guy. Try not to take it. 'cause i don't want my kids to blow up inside of my body but Like when will you take it like headaches. Basically just a headache. If my headache is bad enough i will. I will take an feels. Pretty rare that i actually do but Yeah i mean that's that's that's my go-to because the other stuff doesn't work like tylenol doesn't work. I mean it doesn't do anything for me. It's weird you get headaches like regular No it's pretty pretty. Infrequent say i have been like the last couple of weeks But yeah. I probably have more evelyn last couple of weeks than i have in the last couple of years in the run up to the election. That's pretty funny yeah. I don't never get headaches. I mean the the rare hangover headache. But i don't get just like regular headaches for no reason Yeah no i. Normally don't either. So what do you take you take away. We established a spec- right. Yeah and that's again just for hangover cures. I hate that. That's the only time. I use that stuff but because i don't want to come across his a drunk but it's the rare the rare hangover remedy. Gotcha okay yeah. I think that's what most people use that stuff for to. Yeah it's it's the caffeine and they're really gives you a little boost. Sure but you know all you gotta do when you get into when you're approaching. Fifty is learn when to stop drinking right but the problem is as you're approaching fifty. It takes like one drink to get a hangover. Oh no really sure now. That doesn't happen to you. Know i'm good okay So there was one other thing that happened to when when people were studying aspirin like like this is the point. So many people are taking aspirin that an average dr conduct like a basically straw poll or some sort of study on his patients or patients. not to investigate the effects of aspirin. That's exactly what happened with one doctor. And i believe the fifties name lawrence craven who basically said. I've noticed that there's some sort of weird connection between more blood loss And tonsillectomies that. I'm performing on my patients. It seems like the people who take aspirin regularly. bleed more and he figured out that aspirins. A blood thinner from this. Yes and I guess let's take a break now. It's going to save something for a Surprise but that was the surprise. But.
'There's No Quick Fix For COVID-19,' Cautions Pennsylvania Secretary Of Health
"Going to talk more now about how states are preparing to distribute those vaccines as they become available, and to do that, we're joined by Dr Rachel Levine. She is the Pennsylvania health secretary and also president of the Association of State Health Officials. Dr Levine welcome 12 Things considered. Thank you very much. I'm very pleased to be here. Will you walk us through the logistics for when Pennsylvania first receives its initial shipments of vaccines? I mean, where does it go? How do you keep it cold? What do you actually have to do? Sure. So we're all waiting the meeting of the FDA on December 10th. And then they will consider all of the data of submitted by the Fizer Corporation for the first vaccine. When they issue their emergency use authorization or you away, then operation Warp speed will distribute the vaccine. To hospitals in Pennsylvania and throughout the nation just to get specific is the federal government or or fives or corporation, sending it to the state of Pennsylvania to distribute it to hospitals. I I asked, because this vaccine has to be kept incredibly cold. It's not just like you can send a bottle of aspirin, right? So you are correct. This is an ultra cold chain vaccine that has to be kept at minus 80 C or or Celsius. So it will be operation works speed that will be sending it to the hospitals that we designate now will depend, of course about how much we're going to get, and it comes in trays of 975 bottles. So these have to be hospitals that can Deal with the cold chain and can deal with that amount of vaccine to then administer. Now, the CDC recommends that health care workers and residents of long term care facilities should get first access to these vaccines. That's a large number of people have you decided whether you're going to start With older healthcare workers or people with underlying conditions are only doctors and nurses who see covert patients. I mean, how are you going to prioritize within the priority groups? Sure. So we're going to be developing a decision tree for hospitals to use and we'll be finishing that this week. I want to point out that the distribution for the nursing home and other long term kitchen facilities Goes in a different way. So operation works speed working with Walgreens and CVS will be receiving the vaccine with those two pharmaceutical companies, and then they will be working to administer the vaccine in nursing homes and other long term care facilities. Do you have a sense of how many doses The first shipment is likely to include and how that compares to the number of people in this top priority. First group, so we don't exactly know how many doses we're going to get in the first shipment. So you know, we had lots of discussions with Operation Warp speed, you know, will be looking to attack the end of next week or certainly when they're going to be sent out to know exactly how many doses we're going to get in the first week. And then the expectation our weekly shipments to the hospitals and to Walgreens and CVS for those distributions. I gotta ask a lot of depending here on the ability of operation Warp speed to carry this out effectively And with Corona virus testing, the federal government kind of fell down. I mean, There weren't enough tests. Some of the tests were not accurate. Initially. How confident are you in the ability of this Trump Administration program to get this very difficult job done? We have heard directly from General Purna. You know, we have confidence in them, but I'm sure it will be a significant logistical challenge. This has to occur throughout the United States, all at the same time to all of the states, the territories. And then some specific large cities. And are you also concerned about the smooth handoff from one administration to another? I mean, if the distribution depends on Operation Warp speed, which is a Trump administration program will the Trump Administration only has so many more weeks in office. Now, the Department of Defense under General Karna, you know, will still be there in terms of continuity, But in terms of the representatives from helping human services and the administration, we would like to think that they'll be robust conversation. Nation and communication as the administration transitions. Obviously, that has not happened as much as it should have yet, But we're hoping that all those communications will be going on forthcoming. Just to get back to the scale of the logistical challenge here. This is a vaccine requires two doses weeks apart. Do you have the infrastructure to track and time who has had a first dose when yes, we do. But that is a information technology challenge in terms of making sure that we get the right vaccine into the right person at the right time. And then not only the visor vaccine, but the Madonna vaccine that also is a to dose vaccine. We've heard so many states talk about the extreme budget pressure that they are under and this is an expensive undertaking. Do you have the money? You need to do it? And if not, do you think the federal government is ready to provide it well, it will be essential for the federal government to provide more funding to the States territories in cities that will be tasked with ministering the vaccine. Operation works speed cost billions and billions for the development of the vaccine on Lee $340 million has been allocated for the next part of the mission, the distribution and the administration so clearly states and territories and cities. They're going to need more funding from the federal government to finish and accomplish this mission. These issues you're talking about could occupy you for more than 40 hours a week every week, and you are at the same time dealing with a spike in Corona virus cases and having to contact trace people who may have come in contact with exposed individuals, overcrowded hospitals. How are you juggling all of this at once? Well again. This is the public health challenge of a lifetime. I don't think any of us have seen a 40 hour week. You know, in our memories I stand corrected three ways to deal with the pandemic. You can work on containment that involved the testing and contact tracing very hard to contain a virus that has spread this far. For example, Today we are reporting 11 over 11,000 new cases. In Pennsylvania. It's impossible to contact that many people, so we have to prioritize. We prioritize to congregate, setting such as nursing homes and other long term care facilities, Correctional institutions, schools, etcetera, Then we have mitigation. Basic mitigation sets his mass and hand washing and social distancing. And then in Pennsylvania, you know we had to have a stay at home advisory. And you know, we have really tried to recommend that people avoid not only large gatherings but small gatherings. And then they'll be the vaccine those of the tools and the public health to box that we have to work with. When you're dealing with community spread on the level that we are seeing now, where there is so much of this disease and so much transmission of it. Do you have to change your approach? I mean it, Zeke gone from hand to hand combat to fighting an army out. Imagine it has And so the basic public health tool of containment, which we would do for a small measles outbreak or for it outbreak of tuberculosis? That is extremely difficult for public health to do when we're seeing this type of widespread community transmission, and then we have to pivot to more and more mitigation. It's a very unpopular it is made public health officials sometimes unpopular throughout the nation, but they're absolutely essential to try to stop the spread. And then we have the light at the end of the tunnel, which is the vaccine, but there's no quick fix to hope in 19. After Rachel Levine, Pennsylvania Health Secretary and president of the Association of State Health officials. Thank you for talking with us in the middle of everything else that you were doing. My pleasure. Thank you very much.
Carmen's Immigration Story
"Your favorite cuban dynamic deal is back at it again and this time we have immigration story. I'm carmen and i'm freda and welcome to take it easy carmen. I know you're going to be sharing a lot with us today. Where do you wanna start carmen. If my story. Oh god over the course of my life. I've told the story countless times and every single time tell. Everyone is always so appalled end. It's remarkable it is remarkable story end yet for me. It doesn't really feel that way because it feels like just another thing in my life and on top of that. It's something that happened so long ago. I immigrated when. I was only three years old and so a lot of the details of the story are the recollection of a three year old. And there's also the fact that as i said it is a pretty remarkable story. There's a lot it's not just a lot emotionally but it's a lot politically. It's a lot economically and natural that my parents have really wanted to dive into the subject. Too much over the years at this point it's been over twenty years and only now away really starting to feel like my mom specifically is opening up about any of this but it's been really hard so that's why i wanted to open up and also i just wanna say i'm really excited to share my story because i think the stories are important to conceptualize where we're coming from in the grand scheme of this podcast to just give you a little bit more insight into who we are freed as story is coming at some point soon so we hope that you will tune in for that as well yeah carmen. I think it would be great to hear a little bit more. About what got you to this point. You've been able to have any conversations with your family around your story in terms of asking just to ask my family over. The years hasn't been very open. I i often will approach the conversation and say. Hey mom. can you tell me about the time of time we spent in guantanamo and my mom would say what do you want to know. You already know everything. I already told you everything. And that's kind of dismissive way of going about it. But in a sense. I understand where she's coming from to. She just want to talk about it and the same with my dad and my brother will. He was only eight so he remembers a lot more. He's a lot more open. Now that i have this podcast. I'm able to sort of approach it from a more structured way and say. Hey look for the podcast. I want to know xyz and so they'll start to open up able to ask more pointed questions. But in the past. When i've asked in a more open ended way it's not been something they wanna get into which i think anyone can understand once we go into the story so let's begin yet. So the year is nineteen ninety four and it's august and i'm three years old in nineteen ninety. Four cuba was going through. What is known as the video espec- and this is a special period of time in history when it followed the fall of the soviet union which was a big support to cuba and cuba started experiencing severe shortages of resources from things. Mom has told me that she would go to the store and there would be no food on the shelves to buy. It was difficult to come across basic necessities like soap. Medicine was difficult to find simple medicine. You would need to go to a hospital or have like a hookup to get simple. Things like aspirin and so life became increasingly difficult. I don't remember any of this. My life is for all intents and purposes pretty happy. I'm just a little kid running around the neighborhood and looking forward to starting school my parents at this time new or my dad knew someone who owned the boat fishermen and he had been planning to leave the country with his family on. This book and my dad was a pediatrician. He knew this man from seeing his kids as patients and also from their childhood they grew up together in this really comment like cuba is a very small place uneven. Cuban communities are pretty small in the sense that everybody knows each other in some way. And so this man emi. My dad agreed that my dad and my mom my brother and i this boat with them it was not a raft or anything that he and his family had built over years buying parts. You know it's your first time. Bring up the word raft. And i know that some of you might have heard of the cuban rafter crisis which happened in nineteen ninety four so we know that a lot of cubans like tens of thousands of cubans came over trying to get to the us or at least trying to escape cuba and a lot of them were on makeshift. Rafts put together from pieces of equipment that they found so. It's really helpful that you carmen. You're able to find someone with a boat that was meant to be about let it started the bolt right yes vote. It didn't start off as bad or as a tra- bobby kerman quick aside. Did you ever hear this story. I think it happened later on way. After the nineties there was a scoop of cubans who came over to the us in a truck. No no. I've never seen her but it didn't surprise me. Actually yeah in. This was an actual pickup truck. That floated okay. So it's ridiculous. That's amazing that is as please look this up. You need to see photos of this. It's amazing they made it over to the. Us and a lot of people were following the story because of how ridiculous it was so yeah. I just wanted to take a moment to add color to the variety of transportation methods. That were used at this time. But you know back to little carmen and her boat and this is a common theme in a lot of cuban stories like the sheer amount of absurdity. A lot of things anyway so we left in the wee hours of the morning before it was even light outside. We got on this boat and we left from this river. Called shielded santo
Combo pill alone and with aspirin lowers heart disease risk
"Disease. Still the top killer worldwide and a new, larger national study could give a boost to so called Polly pills, which combined several cholesterol and blood pressure medicines. The study suggested cheap version daily, along with a low dose of aspirin could cut the risk of heart attacks, strokes and heart related deaths by nearly one third.
Aspirin use reduces risk of death in hospitalized COVID-19 patients
"It appears aspirin use can be beneficial in fighting covert 19 Hospitalized Rota virus patients who were taking a daily low dose aspirin had a significantly lower risk of complications and death compared to those who were not taking aspirin. That's according to researchers at the University of Maryland School of Medicine, they found aspirin takers were less likely. To end up in a nice EU or hooked up to a ventilator. That's Jim Crow Sula
White House physician says Trump is taking Remdesivir and 'doing very well'
"President. Is doing very well. I'm Pam Crusoe Fox news that from his doctor Sean Conley moments ago as the president receives treatment at Walter Reed Military Hospital for the coronavirus, Dr Sean Connolly saying, I'm happy to report the president is doing very well. He's not requiring any supplemental oxygen but in consultation with specialist we've elected to initiate them disappear therapy he's completed, his first dose is resting comfortably. That is, in addition to the Regeneron antibodies that the president Not yesterday morning while still at the White House. So Regeneron medicine veer the two experimental drugs. The president's getting then zinc, vitamin D Pepcid melatonin and Aspirin is part of his regiment. That's what we know. So far. Fox is Leland Vitter. The first lady is resting at home after testing positive for Copa 19, a spokesperson said today. Her symptoms have not worsened.
President Donald Trump Taken To Walter Reed Medical Center In Washington DC
"Night at Walter Reed Medical Center. After being flown there yesterday. He's taking experimental drugs as he combats covert 19. Before the president was hospitalized. He received a cocktail of to experimental drugs through an I V I meant to supply antibodies to help him fight the infection. The one time 8 G dose from Regeneron Pharmaceuticals has not yet been approved for treating Corona virus. Trump is also taking over the counter supplements and medicines like Think, Vitamin D the aunt asked the matter dine melatonin and aspirin, which he takes to reduce the risk of heart attack or stroke. The president is a high horse patience, and there are currently only to Kobe 19 Therapeutics with FDA approval for emergency use. Isha has me the president is expected to stay at Walter Reed for the next few days before he left last night. He posted a video on Twitter. Thank everybody for the tremendous support. I'm going to Walter Reed Hospital. I think I'm doing very well. At this point. There are no plans to transfer power to the vice president. Others close to the
Trump to travel to military hospital after COVID-19 diagnosis
"Won't read Military Hospital in Bethesda, Maryland, the White House says. I'll be there a few days working while docks keep an eye on him. Sources close to the president say he's tested positive for Cove it and as symptoms, including a low grade fever, chills, congestion and a cough. Before I left the White House. The president recorded a short message. Thank everybody for the tremendous support. I'm going to Walter Reed Hospital. I think I'm doing very well. President Stocks is Mr Trump is being treated with an antibody cocktail, aspirin, vitamin D and other meds. Mrs Trump tested positive but has no symptoms. Joe Biden, Democratic presidential challenger at a campaign stop in Grand Rapids, Michigan, says that he's praying for the recovery of the president and first lady urging people to wear masks. Chuck Stevenson ABC News So
After FDA Set Back, AI Driven Drug Company Advances with New CEO
"Joining US pleasure beer. We're GONNA talk about far next. It's unique approach to drug discovery and its efforts to develop a therapy for the rare degenerative nerve condition shark Marie Tooth Syndrome. A let's start with the company's platform technology though and its efforts to discover what it terms, his cleo therapies what's meant by the term cleo therapy. Therapy. Comes from the idea of field tropic meaning that that there are often multiple pathways for any drug to follow. In fact that most drugs don't act on a single target but rather act on multiple targets. So for example, we all know that you know aspirin can treat a headache, but it also can. You know prevent clotting by. Platelets from forming clusters that. Eight including so. Many many approved medicine have multiple pathways, and the concept here for us is that diseases are not. Just single genetic kits that that that does exist. But often I'm diseases are the result of an imbalance between multiple pathways and insofar as multiple drugs acting on multiple pathways can correct that that's been the goal of far next our work we call it also polly pharmacology. This is a data intense platform uses a I. How exactly does it work and what's the range of data that draws upon? Well it starts with essential genetic data or G wash data. and. What we aim to do is look at a specific disease and look at the genetic lesions if you will within that disease and then all the pathways that are affected. When there is a genetic lesion liken charcoal, Mary Tooth, and then by looking at all those pathways, we can figure out which drugs or which molecules might interact with those pathways in start to put them together in combinations insofar as the combinations provide. A novel and non obvious exciting results that are true synergies. Synergies meaning that the result is greater than the sum of of each response and we do that with a lot of data. It's a lot of data inputs in a lot of a inputs and a lot of experience in pharmacology by our experts. Working at for next on our teams in. So with a multitude of approaches knowing that the output are combination medicines as opposed to single medicines, we've been able to achieve I think some some remarkable results. The company is focused on using this platform as a way of repurposing combinations of existing therapies. What's the case for doing this from a time cost speed on view? We in the past have I'm combined existing medicines although I would say going forward in the future we'll probably. Use a novel molecules are new chemical entities, so-called ease as the combinations of new medicines. It does afford when you're using existing medicines and much more efficient process however, simply because these medicines are already safe and well tolerated in so you can put them into clinical trials right away in advanced trials and get towards the FDA, an approval usually much faster than starting with a lot of the toxicology work that you have to do. With new new molecule. So it has been for us an inefficient process generally should be inefficient process, but most importantly, it should bring new medicines to patients and caregivers that they haven't seen before. You're focused on neurological conditions. This is an area where there's been great frustration. diseases have been somewhat intractable I. Think of what's happened in the area of cancer in terms of the use of combination therapies is that part of the rationale here that combination therapies are what's going to be needed to address diseases like Alzheimer's on Ls? Right in in diseases like Alzheimer's for example, you know there may be one or two or three. Causative factors but ultimately, it causes a significant imbalance in the brain and rather than addressing the first domino, which is still a huge debate in many companies in among many scientists, we often think maybe by making combination medicines, you can address a lot of the more downstream. Activities. That have resulted in the balancing that could be readjusted. So so as we can make a better new equilibrium with that new equilibrium, hopefully modified disease as we've done. Well. Let's talk about.
After FDA Set Back, AI Driven Drug Company Advances with New CEO
"GONNA talk about far next. It's unique approach to drug discovery and its efforts to develop a therapy for the rare degenerative nerve condition shark Marie Tooth Syndrome. A let's start with the company's platform technology though and its efforts to discover what it terms, his cleo therapies what's meant by the term cleo therapy. Therapy. Comes from the idea of field tropic meaning that that there are often multiple pathways for any drug to follow. In fact that most drugs don't act on a single target but rather act on multiple targets. So for example, we all know that you know aspirin can treat a headache, but it also can. You know prevent clotting by. Platelets from forming clusters that. Eight including so. Many many approved medicine have multiple pathways, and the concept here for us is that diseases are not. Just single genetic kits that that that does exist. But often I'm diseases are the result of an imbalance between multiple pathways and insofar as multiple drugs acting on multiple pathways can correct that that's been the goal of far next our work we call it also polly pharmacology. This is a data intense platform uses a I. How exactly does it work and what's the range of data that draws upon? Well it starts with essential genetic data or G wash data. and. What we aim to do is look at a specific disease and look at the genetic lesions if you will within that disease and then all the pathways that are affected. When there is a genetic lesion liken charcoal, Mary Tooth, and then by looking at all those pathways, we can figure out which drugs or which molecules might interact with those pathways in start to put them together in combinations insofar as the combinations provide. A novel and non obvious exciting results that are true synergies. Synergies meaning that the result is greater than the sum of of each response and we do that with a lot of data. It's a lot of data inputs in a lot of a inputs and a lot of experience in pharmacology by our experts. Working at for next on our teams in. So with a multitude of approaches knowing that the output are combination medicines as opposed to single medicines, we've been able to achieve I think some some remarkable results. The company is focused on using this platform as a way of repurposing combinations of existing therapies. What's the case for doing this from a time cost speed on view? We in the past have I'm combined existing medicines although I would say going forward in the future we'll probably. Use a novel molecules are new chemical entities, so-called ease as the combinations of new medicines. It does afford when you're using existing medicines and much more efficient process however, simply because these medicines are already safe and well tolerated in so you can put them into clinical trials right away in advanced trials and get towards the FDA, an approval usually much faster than starting with a lot of the toxicology work that you have to do. With new new molecule. So it has been for us an inefficient process generally should be inefficient process, but most importantly, it should bring new medicines to patients and caregivers that they haven't seen before. You're focused on neurological conditions. This is an area where there's been great frustration. diseases have been somewhat intractable I. Think of what's happened in the area of cancer in terms of the use of combination therapies is that part of the rationale here that combination therapies are what's going to be needed to address diseases like Alzheimer's on Ls? Right in in diseases like Alzheimer's for example, you know there may be one or two or three. Causative factors but ultimately, it causes a significant imbalance in the brain and rather than addressing the first domino, which is still a huge debate in many companies in among many scientists, we often think maybe by making combination medicines, you can address a lot of the more downstream. Activities. That have resulted in the balancing that could be readjusted. So so as we can make a better new equilibrium with that new equilibrium, hopefully modified disease as we've done.
Trump calls for drug tests before Biden debate
"The president trump has spoken to the Washington Examiner yesterday in the Oval Office and he saying that he would like Joe Biden and himself to take drug tests before the debates begin next month. And they asked him why do you think that Joe Biden might be on drugs INCAS, listen I I'm pretty good at this stuff. He says that Joe Biden performed very well during the debate against Bernie Sanders and he said there's just no way. He can pull it together that quickly let's bless you. Nice little sticky. Your. Trump says he takes one aspirin a day, but he would like drug tests. The V. Before the debate start I think it's at the end of next month and to September Well, you know what he's doing, right? No he saying Yawkey accused me of so much stuff out of nowhere. This. Just so ridiculous even even trying to get me out of office with impeachment and all these things that were made up none of it ever. True. I'm. GonNa Start Making up some stuff on you I'm just going to start coming up with things out of the blue. To throw a show, see what it's like. He did have an interesting about the debate. He said, well, it's a prize fight. It's no different from gladiators except we have to use our brain and our mouth and our body to stand I want all standing. They want to sit down which I thought was an interesting thing. I WANNA be standing during the debate. They won't have chairs so I duNNo. A lot of posturing at this but the part of that is strength. Of, strength. vice. President Cheney has major major heart problems. So when he was in the vice presidential debates when it was he and Bush were the the team. He had to sit down for his because of his heart condition and that was part of the agreement with that. But if you're not, if you're not having, you know if you don't have any kind of health condition that would prevent you from stain I thought they would do. You remember or not but. I thought they would do several debates in several different ways like one would be standing. One would be sitting would be a town hall kind of setting the way I, remember there there are stools and when it was your turn to speak, you would stand and or and so that with the other person was speaking, you'd go back and sit on your stool. Then when it was your time, you would stand and. Come forward to speak to the people in the room that was one of Hillary Clinton's big complaints about one of those debates where they had the stools in a town hall setting and instead of when he was done, he wouldn't go sit back in his chair he kinda stand eight feet or so behind her and just kind of pace back and forth and she said she felt at ver as like it was. What do you call that? He was talking her coming like he was stalking her and trying to be you know what that's called that's called Gamesmanship. What people do he figured out? I'm not going I'm going to change this up. I'm GONNA throw her off her game by I'm not GONNA, sit? I'm going to stand. It's it's it's strategy. Yeah I. Remember when I remember this because I'm ninety one years old. But during the Bush Al Gore debate when they were doing the townhall went on the stools and Bush, was answering a question that was asked to him and Al Gore. Walk Right and got in his face. And he stopped and looked at him like Hey. Buddy. And then just went on with the stuff was a great. You know you've got a good laugh out of it. I mean he taxes he's privacy going. Hey if you get on my space yeah, I, remember that because it was a big deal that. Gore tried to intimidate him in Bush just kind of made everybody laughed in Gore had to step back and then it. A mistake that Al Gore may again, they do all kinds of that little strategy game what they say when they shake hands, what do they say because a lot of times people will say something to kind of make you reek wha, what did that mean rise to make you think before you start but in the the the Romney Campaign Against Obama that vice presidential debate biden wipe the floor. With the what's his name? The Republican? He was the speaker of the House and he he's a Paul Ryan. All Ryan. Yeah he's a he's a fake. Yeah. Fake conservative. And Yeah Biden. whipped him in the debate. Yes. So he's he's not a bad debater if he's if he's Going on his own. So the strategy begins now I guess, of course,
Kimye's Make or Break Vacay, Kylie Turns 23 & "WAP" Backlash
"Okay I. Stop Word on the street is came and Connie has had an exotic getaway with all of their kids to work on their marriage. Of course, we are rooting for them but this is a move lots of stars have done. With mixed results in the past, do you guys think couples know deep down if they're gonNA, make it before they go on these trips or do they just convince themselves that the trip is going to help and they're gonNA work now I think they go like they go intention of it being you know helpful beneficial but I think you know sometimes you go with the Kevin shoot ever like plan something to the t. like vacation or something and everything just completely goes wrong. So you go yeah. Intention of having an amazing time and then you're like Oh, this is a nightmare. Happens I mean I went on a trip you know at a point in my last relationship where I thought Oh we'll get. We'll have a weekend away. It'll be a nice distraction but I knew that was over. Over I think certainly with Brad and Jen when they went on the trip, mean Brad New I'm different out of the marriage because Indian is waiting for me. So I think in this case I think it's a real effort and I think that these two. Are Working on their relationship these celebration vacations that people go on. Solving. Feel like. Hashtag. So Schmidt shirts salvation vacation. I think that if you're going to go on that either you guys go in with this intention of fixing it or really is that last like Lettuce Ryan Save this. But if you're just going in to try and like you don't really WanNa fix things because you know deep down if it's for over one hundred. Going and you know it's over it's just you stuck in a room with less distractions and you're forced to like deal with those things you don't like anyway. So. Really ought to me you gotta be ready to work or thinking. I'm going to do everything one last time I'm going to get one last hookup in I'm going to get you know one last hugging. The other person is thinking I, want to try to save this. So you know you have to go in with the statement engines. Meanwhile, Kylie is thriving as all know it is her twenty third birthday today and we show many questions I mean what the Hell is this I'm GonNa ask you because I don't think you care that much about flowers. Would you this flower display this sort of bizarre flower display or do just want some normal roses? It looks like upside down pineapple. No I No and House. Yeah. I watch. This in my house is taking up the whole first floor like. She has a house big enough to hold it but like this is not going to work in my house in two miniature versions, it's really impressive. If just consider how many flowers that is the craftsmanship that goes into it. Feels like it should be at some sort of like of event like a homo. Championship, where people are walking around like there's thousands of people story she had this. Little white you're doing you're destroying hundreds of flowers. One person to enjoy maybe a few people. If it's her family, it's just a lot and can no. Aspirin and they're known for the over the top flower installations. We see them at every holiday every Valentine's Day every birthday and they're usually really beautiful. This is the first time that I'm kind of like does she like like I don't know even her style and it does now I can only see pineapple also she's sending these to herself right? Like we don't think someone sending them to her. It's not like with she knows her cell like she I think she I don't think she's sending them to herself I. Think She's setting these things up and she's like mom it's my birthday and I need to have a happy birthday Kylie by the pool. Like this standard this is like brushing your teeth rally you would send your own like Happy Birthday, Senate Oh. I am that desperate I. Don't know why you think I'm not like I as McQueen of just doing anything to make myself looked a little more love look. Yeah. No I would do it anything. You'll see. Meanwhile and everybody was going crazy over Cardi me and meg. Song Walk, which stands for I'm just kidding, but it's not all good. Some critics want to ban the song saying it's too sexually explicit vile and quote sets the entire female gender back by one hundred years. So dots on this guy's what he thinks about this. A both. For those that don't know. Stands for what? Is. but in terms of their argument at this is setting the female gender back one hundred years. The female gender was way far back on hundred years ago, and it wasn't because they were embracing their sexuality and taking control their own bodies because other people aren't doing it. So if anything's GONNA, take the female gender one, Hundred Years Back. It's someone telling women what to say and do like they're doing right now. Man Who tweeted his criticism of it and says that he watched the video accidentally I how? Do you watch this accidentally you accidentally watched it over and over on repeat on. Youtube. In, other news five in cows recovering after breaking his back in his home in Malibu hikes he hit up twitter after a six hour emergency surgery saying some good advice. If you buy an electric bike, read the manual before you write it for the first.
Cyber Safety, How to keep your identity protected using mindfulness and practical tactics
"How you doing Sandra? Hi. How are you doing? Thank you for having been your show. So, matty here. Right absolutely. So we're talking today about identity and cyber. Theft here. So give us a little bit idea on what that's about what does identity theft what is cyber theft? What does all that stuff? Of course? Let me start why I started. Niger, any may be. Definitely will get into into whether they cybersecurity are cybercrime or identity out. That okay with you. Sure. So I was returning a many many years ago I was returning from these things. Colombian. So I mean, the plane were landing in Miami and the pound announces that Homeland Security. Were boarding the plane. I course to ask for a handed to the to the agent and at the time I, head out these. It was relocated recently to the US. Ns I had my passport to the agents. then. He's next thing I know I'm the only one that being score of the plane by the two officers. And enthroning to the room you the. Famous rooms. that. Are In airports in I, don't know what's happening. Out. I'm about to connecting fighting my husband's waiting for Chico. So ten hours later and handed back my passport and is revoked. Few weeks later I mean Venezuela my native country and I'm trying to process my. Mom to processing again, you sign I had a lot of support from Maya Turks from my former employer journey. So we are in to again and. It was interesting officials. They kept asking me about China. Why we're doing China. China who is your contact? Like I never been in China. beating know what they were talking about. Some how when? S Model China go to hold of my information and was smuggling women into the US using my identity. Yes. So humid slate, you know everything I convinced, of course, a smuggler I gave my new visa and a back home two weeks later and returning from Euro my job requirement to travel a lot. And as we are going to. Control. I. Give My passport booth. I'm right back into that room. Because I have to. The, real me over and over that for six years. Yeah. So when I going everything was Chinese I. Mean it was really crazy at nobody wanted to travel with me a united in my almost wanted to travel with me. and. Finally. made the citizenship, my aspirin I changed my. Everything Courses Okay and at the time I was working tonight not. Having in the industry for over Twenty Years Community? It non no it was identity. It was not in the news. He was not like every day right now at breach or cyber drive or this or that. Back back in that day in that time, it wasn't so I couldn't make the connection. So few years later, I changed my career and I join cybersecurity cybersecurity? Area. Industry. And I realized what happened to me, and what happened you know when someone takes your identity with Tony, personage you for their gate. and. You know eat my corporate career I did that I? was very passionate about. Training and education awareness and Allison Park job that I enjoy the most. So I wanted to Redo it at a bigger scale as I left my corporate all by did your original question about what is at Know when stolen takes something from you. And wince when they break into your life, and that can be very dramatic experience and it can be for many reasons financial reasons it could be for. Someone inside your company that has. Either made a mistake or by attention. Jober that is you and ninety. Attack you could be for like in my case, there was a vying for for that criminal to have my identity so he can use it for him. So there are many life happens. It's It goes on all the time. We don't always hear about identity theft on the news I might do commercials about it. You know when the advertising different products, but it's something that a lot of us don't even really hear about. So how does that happen? How does someone? Get your information. So you can happen. Through many different things that can happen through your social media, it can happen through your email can happen through when you give out your credit card in a restaurant. It could happen when when when you ride formation with with a doctor. Often, office I mean, there are so many ways. Jury information can be obtained. We share a lot in social media share. Many different things. That are personal and that that is one thing that can use. Of you do that. You know sometimes we don't hear the news a lot about identity issue i. think we should do a because there's a new victim, every two seconds. A new victim I mean someone right now? has just being victim of identity DOPP and there's different decrease appointed. You know sometimes we someone let's say takes your credit car. And data charges in your credit card and probably most have had situation and the bank context you. Just have to get a new credit car. Scare of it. So it's a degree of identity theft is in the financial. Hesitation of identity theft, but it is. Your credit car on and bought things on your behalf. But it wasn't as faithful as many other situations are obviously. More were personnel or or moines more invasive.
UFC 251: Kamaru Usman vs. Jorge Masvidal
"Island becomes a reality. Well, I guess it's already a reality. But there will actually be fights there, and it's actually Gosh! Maybe one of the best certainly form in my opinion, the best card they've had since they've come back the UFC But really good card. A lot of big names. And then, of course, the main event of the evening is a fight that Probably should have been on the card anyway. What We ended up plucking out, I suppose. With Moscow it all being put in against Guzman. So I wantto talk a little UFC 2 51 Maybe Look at some of these potential wagers and get Ah Someone who used to frequent this show. It needs to come on on Maura, and that's on me. Scott Kanevsky joins me now, Scott. Good to catch up, man. How are you? I feel like a first time long time been awhile. It has been a long time. And how are you? How's the family? How's everything going doing well, and I appreciate you having me on thinking about me and things were going well, and things are only gonna get better tomorrow night. Yeah, absolutely. Did you laugh at Dana White when he said when he first brought up Fight Island? Yes. And no. Because you know you crazy enough that he was probably speaking the truth. You figured, you know, maybe he has something going and he's crazy enough and has the money the backing toe pull something off like that, And sure enough, here we are. I mentioned at the beginning How good this card in is and it's not just mustered all versus Guzman by it. Man. Did we luck out? Right? I mean, my you know, I feel bad for the dude who had to pull out and it doesn't get a fight Guzman tomorrow but as a card, it's so much better now that master dolls on it, don't you think? Agreed. Gilbert Burn, We'll get another shot at some point. I mean, hopefully next in line for whoever wins tomorrow night. But this is a fight Everybody wanted. You know, already. Mas Vidal inducement aren't exactly the best of friends. They've been talking for a while. They had that the altercation back in the states. It was Super Bowl on radio row. So this is something everyone's been wanting to see. And now with Byrnes Contracting Cove it we're going to get it on. I think that's just made a already really intriguing AA fight cars that much better. Now I got burned by Justin GHT because I was all in on Tony Ferguson in that fight like it's not gonna happen. It's not gonna happen twice, right? I mean hospital is not gonna win. This thing is he Okay. From a mm a standpoint, I have to say no. And I would agree with you. But if you're going to talk, betting going all in and you've seen what's happened over the last 24 36 hours. Money is just money and tickets are pouring in on Mas Vidal. He's he's gone from about a plus 2 25 plus 35 to a plus 1 85 last I saw earlier today. I believe there would be MGM believe put out there that they're taken 81 ticket being booked for Mas Vidal. And you know, you know what they say. You gotta follow the money. So it just Somebody knows something, or is it just It's obviously not just big bets that are coming in on Mas Vidal, but there's no number of that's coming on him. And that just makes you wonder if someone I'll be just like you know where agree like you. It was all set up for Tony Tow. Go in there and handle him and take him to the ground and didn't but You know, maybe he'll learn from that. Now. What's what's mobs but all going to be able to do to be Guzman. That's the big question. You know, he's better on the feet, obviously, but you know who's going to try and take him down and out wrestling? So How? How does Ma's little battle that and managed to Ah, toe? Hold him off? I don't know. I think I'm right there with you. And I just looked at Fanduel and they have mustered all that plus 200 right now. So even though that's a little bit longer odds, then maybe MGM has that still down as you said Scott from 2 25 or something like that just a couple of days ago, and I guess oh, so let me ask you this if we do the betting thing I I have Guzman minus 2 45 or mosque it all plus 200 Or and then of course, you could get into it. Um, I took in my parlay. I took Guzman just straight up because I got enough other stuff in my parlay that I'm going to get pretty good odds out of it. But if you were laying down, Abed, would you would you do it smarter, Would you Dumas fit all Okay, so I would I would wait until about 15 to 30 minutes before fight and see where those odds are because of who's come down to, like, minus 200. I think you jump on him because they're getting more value for him. And firstly, I think he does come through with the wind, and he's just going to grind it out. But if that money starts about bounce backto mas Vidal, you know, I think, and you're looking to take a shot. You're willing, you know, maybe you had a good night on the earlier fight. Maybe maybe you going on and on and you take that shot. Just hope he comes with that flying me. He landed on aspirin
"aspirin" Discussed on NewsRadio KFBK
"Ask and ask to aspirin and a glass of water it's two glasses of water into aspirins because we don't have enough water in our system to take apart are medications or to to dismember the chemical content material content of our food and all of these are having impact but the upstream solution is getting not more hydration but better hydration what is what percent of people do you think are dehydrated walking around and they don't even know what well I am a fan of doctors act bush's at triple board certified physician brilliant young physician who's really wow the medical world his specialty is hydration and he says a hundred percent of the people come to see me are dehydrated now I'm not surprised by that because I am an anthropologist looking at the environments that we live in and I know that modern environments whether it's driving in commutes with cars or trains or riding the airplanes or going back into those offices where its duties are very dehydrating environments then we add on top of that now George were using and this is why I think we're even more dehydrated then we were say five years ago or seven years ago with the advent of the cell phone really how come my computer use your cell phone is dehydrating how so well that phone is bringing frequencies into our cells and water is the most sensitive of all the receptors body you're changing the frequency your reorganizing the water molecule and so that it's a big problem plus you know phones are hot computers are hot and then another though so that's two places that they affect this the third place is when we're on the phone we tend to lean forward and our whole spinal canal or synovial fluid to going down our spinal canal is constricted just like a garden hose in fact when we sit and are we are we are so in more in mobile in this society that our whole canal systems our whole inner irrigation our king and not flowing freely as they would if we were standing more often or walking or moving around more than we had a doctor on the program a million years ago I called him doctor Batman and yeah he he wrote a book about this your body's many cries for water yes it's a brilliant tax he was really the create the preeminent pioneer showing that water is the upstream solution when he had no other medications to offer the his fellow prisoners he was unfortunately a victim of unfortunately a victim of the Iranian revolution he was ordered it to be the positions of the prisoners yet he had no recourse to any kind of medications the only thing they had was a water fountain Jeez and he was really able to document how he treated so many different conditions just by improving people's hydration tell us a little bit about the book quench working people get it yes well it's on Amazon it's at any local bookstore would be thrilled to have you there's that we've we wrote it because we are very concerned about not just making people drink more while at the same time recognizing how important high creationists so we put fifty recipes in there of the highest hydrating foods we could come up with and we love sharing knows we just love sharing of storage because their gentle they're nutritious there lovely to eat and they really improve people's mood and their greatness in their alertness they're very ability to receive more life if I can just people no I prefer water at room temperature as opposed to chilled in the refrigerator what do you think that's a good thing in fact the Chinese have a tradition going back thousands.
"aspirin" Discussed on Stuff You Missed in History Class
"Hello and welcome. Welcome to the PODCAST. I'm holly FRY and I'm Tracy Wilson and this is our Our what we're starting to refer to as casual Friday. Yeah our little Our little chat Yeah so I. We're GONNA talk about the invention of aspirin because I did not realize I had long heard the stories of willow bark being chewed chewed on by people in ancient times as a treatment for various maladies but I didn't realize One I Edward Leigh. I am not a chemist in my high school chemistry experience was Shall we say less than installer. The teacher was amazing but I really struggled with it and so like I think she kind of just kept like passing me along just out of kindness. Because she's like how he's never going to get excuse and she was amazing and my all of my best friends were really smart at it so I felt like just the stupidest person on earth but I I did not really understand that. Saxon and salicylic acid are two different things because in a lot of casual literature that is not like a peer reviewed scientific scientic journal thing. They get used completely interchangeably. Dah well and the thing that our listeners will not know because they will have all been removed from what we recorded I incorrectly call it sal. Silicon every time I needed to say the word and I had to see what we always run into words like that for both of us I feel like I. I think it's just probably a word that got in my head wrong at some point and sort of stuck there. Yeah I also. I was watching several chemistry videos Trying to kind of wrap my brain around it with mixed success and I kept marveling because sometimes the way that that chemists pronounce things are very different from the way I ever learned them and then I think probably these words are said so infrequently by the general public that nobody really we get to wadded up about Pronuncia since most of that work is happening on paper and is being documented rather than just just orally Shared by like in the scientific community. They probably don't get as as weird about it yet. Somehow that reminds me I was. I was taking some transit transit the other day and I'm not going to name any names because I don't WanNa throw any brands under the bus But there was just a billboard with a picture of the product and the name of the the product underneath it and then underneath that said it's pronounced and then a rendering over pronunciation that did not look like how you would say that and I was career why you got a name your product. Something that requires an explanation for how to pronounce. It is not intuitive based on how you spelled it I would so love to fly on the wall in that marketing discussion. Yeah we're you know there are some executive way up the food chain. That Lake just decided with the name and then they're all like well. How do we communicate this? We make it part of our brand Dan. He's eventually we. We're going to have to give a phonetic spelling and when when we were talking about where the name aspirin came from and how the other letters correlated with things and this the ending of I n being popular at the time I made me just sort of dwell in in my mind for a moment about like pharmaceutical naming today and how just bizarre and random some of it can seem like it. It does not like a lot of the things when when you're watching TV and you're seeing the ads for for drugs. Sometimes it's like did you just put letters into a hopper. pull him out. Wanted US out of this work I did. I didn't end up using it as a source but I did while working on this episode stumble across essentially like an article that was written and by I think it was two experts on drug naming in a lot of it was about like trying to separate yours from others and how sometimes that means means that you have to do some things that are counterintuitive. Is this how we get crazy medicine. It's like people are just trying to be different. I feel like this Reminds me this is a big leap but come with me of wedding dresses in the nineteen eighties where everyone wanted to wear white but also wanted to look very different so so some very crazy design started happening. I feel like it's kind of the same thing everybody wants to sound. Scientific reliable you know comes from a place of great knowledge but also different enough. And that's how you get. Some of the nutty brand names that we have for drugs is my guess. Some of them are pretty pretty far field. Yeah I'm certainly very grateful that we figured out this whole aspirin. I also didn't realize that like to make it more palatable palatable and there are still people we should be clear that even in its its most easily digestible form still can have trouble With their their their GI tract from it. And from anything you know different. People are going to be sensitive to different things. But I didn't realize that your body is like doing such a big lift in terms of converting it and from the stable thing that you could digest to the thing that actually delivers pain relief gay. Yeah I'm learning. I'm learning nope which is always the ideal so our second episode this week coming out on Christmas Day was on the raccoon churches in Ethiopia. The complex called called LALIBELA. And I said this is the end of the show but I want to say it again as I was working on this there were times that I thought I wish this were a video podcast which I don't really wish because because that is so much more labor involved than the podcast we currently have but man. It's hard to convey how amazing those churches ages were without looking at them. I say were there exists Yeah they're spectacularly beautiful and just Brain breaking in terms of like how they were built it in some of the pictures that you will see you will see folks sort of clustered around the edge of the rim of the trench that circles the churches just with their feet dangling over and I look at it and I'm like man I am terrified at the at the idea because when I was a kid I was really scared of heights and that was something that I was able to move through in my young adult. Don't years but still occasionally if I'm in a high place I get a little anxious about it and just seeing sort of the the people some of whom had come on pilgrimage to just sitting getting around the edge of this four story deep rock. Trench was I guess both inspiring and terrified. I can understand that I think I'm more freaked out by the people standing around it. If they're sitting I feel well. I think I would be able to sit there but I would not be able to stand and lean over and look down without panicking and probably causing my own fall. Yeah yeah sitting great though. Somehow that reminds me of when I was eight I was a youth. I don't remember exactly how old I was. But it was. When Halley's comet came through and my church that I was raised in Organized a little trip up to a local mountain top to look at the comet and and this kid who was about a year older than me was so anxious about the other kids who were Kinda up there playing because there were younger kids also and there there was a a hang gliding ramp and they're hanging around the edge of the ramp and he was just so terrified that he was about to witness a tragedy agitating so yet the other thing. That really struck me. When I was doing research about this was how aw colorful and vibrant this stories that were part of it? That are part of the Ethiopian Orthodox religious tradition. I really loved the imagery. Injury of of King Lalibela being surrounded by bees. Yeah and I also really loved the Whole Story About Mental Act the first go into visit Salomon Salomon and coming away with the Ark of the covenant. I kind of want to go see if I can find more accounts of how that might have gone down because because one of the things that I was listening to about it kind of described it as like that he was either given it or he just sort of removed it the intensive that being a little less clear and then as you said it It also reminded me of Indiana Jones as I I was working on that. Yeah don't Don't open that ARC. That's what I know. Yeah well it's treated in an incredibly sacred way All the ARCS are the story. Is that when the Ark of the Covenant was returned. It's been guarded by just one. Monk and a lot of the REPLICA ARCS. That are in the lally Bella Complex are similarly like they're in a part of the monastery only one person or a very select. Few people are even allowed into the area where it is kept so you can look at the UNESCO website for example they have lots and lots of pictures of what these churches look like. Stuffy missed in history classes the production of iheartradio's. How stuff works for more podcasts? For my heart radio. visit the iheartradio you Apple Apple podcasts. Or wherever you listen to your favorite shows. I'm Zoey Deutch. I'm Amanda CEO's Hey there I'm Bellamy let me young and today I'm GonNa talk about what I wore when I- auditions for scandal. Welcome to what I wear when production of Glamour and iheartradio. I'm your host Perry sabotaging each week. I'm sitting down with a woman. I find fascinating to talk about what she wore during a pivotal moment in her life. Listen to what I win on the iheartradio APP apple podcasts. Or wherever you get your podcasts..
"aspirin" Discussed on Stuff You Missed in History Class
"The all new two thousand twenty Ford Explorer. Tracy I know that you have been thinking about an interesting thing lately. Which is what your pick would be for the greatest exploration vehicle GEICO of all time? Yeah I'M GONNA go with. The research vessel petrol that was owned by the late Paul Allen found so many shipwrecks which our listeners love that we started to make jokes about it and this shipwreck. That wasn't found by that vessels. Well The all new two thousand twenty. Four explorer is the greatest exploration vehicle of all time time there are a lot of places that have been explored by other vehicles but this vehicle the Ford explorer is going to take you to places that you might not think of as explorations but really really can be for example. Maybe you navigate your life and you have to get around town which can be a whole big problem especially if you live in a city like Atlanta. We're traffic tends to be congested rested. Sometimes you just want to go on a great vacation and riding in a perfect vehicle makes it the ideal ride or even just mundane things like going to the grocery store. Sometimes that is a true feet to achieve. If you buy groceries the way I do you can do all of this. And more with the all new twenty twenty Ford Explorer. That's the all new. Are you twenty two thousand Ford Explorer. The greatest exploration vehicle of all time The German patent.
"aspirin" Discussed on BrainStuff
"Combining their industry expertise with the open source leadership of Red Hat. Let's unlock the world's potential essential. Let's put smart to work learn more at IBM dot. com slash red hat welcome to brainstorm a production of iheartmedia. Hey rain stuff lauren vocab here the average headache backache often sends people reaching Willy Nilly for the nearest bottle of over over the counter pain reliever but for best results. It's smart to match the particular problem with the particular pill. That's because the wide variety of pain relievers known in medical circles as analgesics available today are each effective at different problems and come with different risks. There are two categories of pain pills suitable for home use this non steroidal anti inflammatory drugs more commonly referred to as m saids end. Acetaminophen both are considered anti redick's which means that they can can reduce fevers. Most people know Acetaminophen better by the popular brand name Tylenol but there are other brands as well like fever all the category Korea is broader things like aspirin ibuprofen and Naproxen all fall under the umbrella. There are others but these three are some of the most widely used each each has its own range of brand name versions so which one is best to use it all depends on what you're taking it for Acetaminophen often sold under the brand name Tylenol was approved by the US Food and Drug Administration in Nineteen fifty one but how it works still not clearly understood but we do know a bit about what it does we spoke by email pharmacist Terry Thompson Dr Pharmacy and VP of Clinical Services at innovation compounding. She said Acetaminophen does not decrease inflammation but works in the hypothetical to reduce fever and it may work peripherally to block the generation of pain. It's best taken to reduce news fever or symptoms of pain from flu like illnesses headaches arthritis and menstrual cramps but note it will only mask the pain without treating any underlying inflammation inflammation problems that caused some of these symptoms. You should not take acetaminophen while consuming alcohol it can be hard on the liver. Even when you're stone cold sober and much much worse when consuming alcohol most serious liver problems have been reported following large doses the highest amounts considered safe is three thousand two hundred and fifty milligrams per per day or ten regular strength tablets however there have been instances when liver damage occurs after medicating with moderate or even small doses over a long period of time cinnamon offense should be taken carefully in conjunction with other medications as many headache and cold meds like Nyquil already has been in them. This can lead to accidental overdoses anyone taking one of these extras should carefully read labels follow dosing instructions to the letter. It's considered safe enough to take by just about anyone anyone but occasionally side effects are experienced most often those are nausea rash and headache which is pretty ironic considering that that's why many people take it in the first place is so that's CNN now. Let's talk about these are sold under brand names like Bayer advil Motrin and leave you know how often doesn't do a darn thing to reduce inflammation well and sets pick up that dropped ball and run all the way into the end zone with it short for non steroidal title. Anti inflammatory drugs the category of end says include a variety of analgesics like aspirin one brand name being bear ibuprofen such as advil Motrin and Naproxen oxen like aleve although there's some variation by particular type and says in general work by blocking the production of chemicals called prostaglandins which encouraged fever a pain and inflammation these effects can be useful in promoting blood flow to an injured area end in telling you to watch out and not further hurt and injured area but there's is a point which it's like dude body. I know I shouldn't walk on that foot. You can stop telling me so hard and said go out of their way to denote non-steroidal in the the name because steroids can also reduce inflammation but the way steroids work by depressing me. Immune system is a major distinction. So when did you take 'em Ed's Thompson said those with inflammatory conditions such as osteoarthritis rheumatoid arthritis menstrual pain or muscular pain would benefit from an end said the proximate intends to work longer in the body about two times longer so those with gout or more chronic pain conditions may see more pain relief from using naproxen verses ibuprofen however ibuprofen provides quicker pain relief than naproxen end is less likely to cause an upset stomach so might be more appropriate for strong and sudden pain have hangover skip these Dominican in favor of An said although nothing short of time rest and lots of hydration can completely cure a hangover the anti inflammatory Tori properties that end says boast are believed to be helpful however taking an end set on an upset stomach so common with hangovers can make the discomfort worse so don't take it on an empty stomach will ever but especially in the case of hangovers aspirin has long been used as a daily supplement of sorts for people at risk of heart attack and stroke because it inhibits potentially tragic blood clotting for roughly four to seven days one important caveat however is that people consuming aspirin for that purpose should should use a lower dosage under three hundred and twenty five milligrams per day than those using it for pain relief purposes. Thompson says that aspirin is more commonly used nowadays for inhibiting opening blood clotting then for relieving pain due to intestinal bleeding risks which brings us to when not to take them women who are pregnant or trying to become come pregnant are typically advised to avoid use of because they're believed to cause fertility issues early miscarriage and even birth defects in particular they should not be taken in the third trimester trimester because they could cause premature closure of a particular blood vessel in a developing baby people with gastrointestinal problems might also steer clear of and said use negative active gastrointestinal side effects like ulcers or intestinal bleeding can occur because as we said Prostaglandins aren't all bad prostaglandins protect the stomach lining and help with blood-clotting when those functions are inhibited the risk of bleeding and ulcers goes way up. Thompson said although this is more likely in those who take large doses for for long periods of time patients often turn to a seat from leads for pain relief since it does not cause intestinal issues still confused about which to take the talk to your doctor or the pharmacist local pharmacy. They'll be able to make a recommendation and point you towards the correct product..
"aspirin" Discussed on This Podcast Will Kill You
"It's really. Very few things that I remember from, like, original BioChem in this is one of them because I think it is just so. So fascinating. Oh, I love it. So that's how it works. You have aspirin that binds irreversibly to Cox, it blocks the activation of platelets. It does. So for the whole life of that platelet, if you don't have activated platelets, you don't have clot formation. If you don't have clot formation. You don't ACLU your arteries, if you don't include your arteries. You don't have a heart attack bloom. Simple one two, three four. I don't know how many steps there were there was a lot. I understood it matters a lot for any medical texter. Yeah. So I've been pro Finn which is another and said, it's another non-steroidal anti-inflammatory it works very similarly. But again, it is reversible. So it's not gonna have that same long lasting effects Tylenol, or acetaminophen or paracetamol as a millionaire. Is not quite the same it actually it's not entirely clear, yet, how Tylenol really works. We think that it binds Cox. But it does not do so in your peripheral body, but it might do so in your brain. So Tylenol isn't technically an anti inflammatory. It does not have anti inflammatory properties. It does have analgesic properties. So it will it will reduce pain, because it works on your nervous system, and it will reduce fever. So it's what we call an anti Rettig. Okay. So really quickly I guess we can just talk about. Like when you would actually use aspirin. I don't know. Do you wanna talk about that? Yeah. So, like I said, there is some evidence that for certain populations aspirin in small doses can be used to lower the risk of future, a myocardial, infarction, or heart disease. There's also some evidence that it can be effective in lowering the risk of some cancers, especially colorectal cancer. And this has to do not so much with its effects on clotting and throw boxing's, but on its inflammatory anti inflammatory effects because number of cancers processes were sort of learning this more and more are associated with prolonged inflammation. So if you think of something like something, like all sort of colitis which is a very high risk for colorectal cancer is an infla-. Matori bowel disease, singing, have constant inflammation in the colon and that puts you at risk for developing cancer. If you can reduce the inflammation, you can potentially reduce the risk of cancer. That's the thought. So does that go back to what you had told me a couple of weekends back, where anytime you get a situation where sales are constantly being asked to replenish themselves. You always run the risk of irregularities in cell division in this cancer. Exactly. Mind blown. Now, I also want to say I'm gonna give you two disclaimers. Number one, baby. Aspirin is called baby aspirin because it's eighty one milligrams of dose, rather than three hundred twenty five which is like grown have aspirin regular aspirin like aspirin. You take a headache. The adult aspirin. It does not mean that you should give baby aspirin to baby. Because. Bad naming. It's a terrible name for some reason, and it's not clear. Why this happens if you give aspirin to children under basically under teenagers? It can cause a very, very serious disease called Raya syndrome, which you mentioned Erin, which can lead to encephalopathy, which is swelling of in brain liver, failure, and death. It's not clear. Why this happens? But that's why in general, the recommendation is never ever give children aspirin, if they have a fever, you give them, Tylenol or maybe Motrin, which is proven. Oh, so thought explains the Tylenol okay that my childhood makes a little bit more. My mom was listening. Don't give babies aspirin. Thanks, mom. And the other caveat that I want to make is that the evidence of the effectiveness of long-term aspirin treatments is still quite mixed. It's not clear that every single human is gonna benefit, and it is absolutely not the recommendation that every adult needs to be taking baby. Aspirin, so to be clear. I am not yet a doctor who can make those kinds of recommendations. So I am not suggesting that everyone go out and start taking a baby aspirin..
"aspirin" Discussed on This Podcast Will Kill You
"They went back through their development records and found a chemical by the name of n acetyl para a minute, phenyle, which appeared to be an analgesic. But with some nasty side effects so they revisited as chemical, which they called a CD benefit. Oh, yeah. And didn't find any of the side effects that it had that had halted its earlier development. Boom new drug created perfect done. I had no idea that they are also made Tylenol they call it Panadol. So this was they called it acetaminophen. And then in the UK it became known as paracetamol and it. It's brand name was Panadol. And so it was like it's flew off the shelves because this was this non stomach irritating aspirin alternative and aspirin kind of just started to slip out of the leading place in the market. And in the US say Dominican, of course, would be Tylenol, and I pro- Finn was not far behind. And so, by the nineteen sixties, the trio of aspirin acetaminophen slash paracetamol an IB pro fin dominated the over the counter analgesic market and aspirin continued to slip until the nineteen eighties. And it took a major blow when the link between aspirin and raise syndrome was discovered. So just when things were looking pretty grim for aspirin its renaissance would begin. Who all of this history of aspirin that I've talked about so far? There's a lot of history there. Sorry about that. Its mechanism of action was still unknown, though a new how it works. Yeah. It's funny because there wasn't much interest in finding out the mechanism of action and till nineteen Fifty-eight when a dude, a chemist name, Henry Collier, decided to play around with it, and over the next decade or so Collier, along with pharmacologists Priscilla piper in John vane. They worked together sometimes separately, sometimes on the same project to uncover the mysteries of aspirin, and I'm not gonna go into the whole thing. But essentially, what happened is that John vane made the final leap, and he and piper would publish the results in nature, where it became one of the most cited papers of all time, Cuong, vein one, a noble or was awarded a Nobel prize for his work, pharmacology understanding, the three main effects of aspirin, so pain reduction. Inflammation reduction, and reducing the ability of, of blood to clot did more than just solve a scientific mystery. It also held huge implications for the uses of aspirin, one of these being that in small doses. Aspirin had this affect on the bodies causing ability. So in the second half of the twentieth century, and through today, of course, heart disease is a leading cause of death in many industrialized countries such as the US in parts of Europe. And this anti Cottingham ability of aspirin also meant it could be used as a possible, heart attack preventative and despite many successful trials. This idea was slow to gain traction, but by the mid nineteen eighties, it was finally accepted, which meant new branding and campaigning. In the marketers back to the whole aspirin advertising situation..
"aspirin" Discussed on This Podcast Will Kill You
"A law was passed restricting promotion of a patent drug just the name of the company and the name of the drug. That's it. You could just say this is the name of the company. This is the name of the drug. See can't say like what it does or. Nope. Not at the time weird to stink and only non trademark drugs called by their generic names could be included in the in the official US pharmacopoeia. Oh, yeah. That's still like we only learned non-trade names, this, what's on the, the US, Emily tests, and everything, wouldn't make sense. Yeah. Yeah. All of this trademark patent advertising controversy is going down in the early nineteen hundreds and guess what happens in nineteen fourteen. Titanic note. Twelve I actually knew that the defenestration of Prague, God the dust bowl. Went once the dust bowl actually reading. Grapes of wrath. Okay. All right. Well, World War. One is what happens. And so, with this outbreak of war, citizens of the UK or like we're not supporting fair is a German company. But that was easier said than done first off large scale manufacturing of CDL sell silk acid was logistically difficult and many chemical companies had switched to making wartime things. Explosives poisons whatever. And doctors were still prescribing aspirin capital a rather than seato sell silk acid. So buyer was still making a killing, and they also were making mustard gas. So they were also making a chemical that was doing killing. Yeah. It's a sideline as we've learned. So. Yeah. So bear with so making a killing, but that was only until the British government board of trade nullified, the trademark on aspirins name, and it made it public property. Yeah. Because now it's just Aspen lower case. Yes, I never put together there. Yeah. Okay. Maybe you'll remember some other things that happened during Woodward one that are relevant to the podcast like the nineteen eighteen flu. For example. Yes. Precisely get one. Even though early rumors went around saying that Bayer made aspirin was actually responsible for spreading the flu because it was a German company. Right. But soon people got over that and were popping pills, like crazy, which, actually recent studies suggest may have actually led to excess death due to influenza, particularly in those age groups that were the hardest hit is really interesting paper on that. Yeah. So after World War One though the aspirin market became a free for all and tons of different companies.
"aspirin" Discussed on Z104
"In. Siegen? Aspirin. Binion. Come back. Still.
"aspirin" Discussed on The Rich Roll Podcast
"Crucial aspects of our success equation so i can easily make the argument for example that my my perfectionist standard control issues that's how i was able to even get here to this place where i get to sit here and talk to you and if i let go of that that's very threatening that's terrifying right because that means that i have to come to this decision that that that that is in fact not what's feeling my success and just coming to that understanding is difficult and it would then put me in a place of confusion and mystery yet okay so what you're hitting on big time right it's almost like what would be a an easy example is that okay i have a headache and so the docker someone that i trust take aspirin you take aspirin for headaches i get a headache don't get to accept much action that like whatever it is right you take you take something for headache and it works like okay good okay and then at some point you say stomach ache you go into the doctor the stomach ache and let's a little test oh you've got some ol serves how often do you take the headache medicine why take it three times a day no no no you gotta stop doing this too much but it works i don't have headaches but now you have an ulcer so it's a little bit like this system that got you here and i see i see this all the system that got me to a certain phase of my life getting this phase of my life has worked but there's limitations and i see it with like world class athletes that say you know what got me here i've got two gold medals i've got this that and the other accolades but there's another space that i need to figure out because this is no longer working anymore and so it's like now the question is do you stop taking the medicine.
"aspirin" Discussed on WTRH
"To feel normal is kind of like if somebody goes out for it they have a matter of fact i explain this to a judge in a corpse seizure if somebody goes out and they have a drink you know to relax to socialize to have a better time i have no idea why people go out have a drink i said they do it in my mind lighten up a little bit relax well why wouldn't somebody with a mental illness to this you wanna talk about something that needs to lighten up and i'm not justifying it but we are finding more and more that this is what happens they self medicate and that's why are you know opiate use and all that is so high from this and it's important to understand drugs kind of drugs were talking about we're not talking about aspirin kinds of drugs that we're talking about they are all mood altering right they are so with alcohol there are certain characteristics some people will say well that just helps me numb out to learn about it's a depressant that's what the classification now what you have in regard to the drug of the we're talking about their their several types but with alcohol which are all would be depressants it's there years ago i learned that they shot of alcohol the killed millions a brain cells that the problem that you have is you love your son you care about your son you know he has a mental condition and you would like for him to be as sharpen his bright is he could possibly be to be the maximum that he could be is that correct okay good and and i know i just believe that about you the problem with if we're just gonna look at alcohol we're talking about impairing it it impairs the brain it doesn't help even though at the moment if someone were perhaps in a manic stage that's bipolar manic depressive so if someone.
"aspirin" Discussed on VIBES-LIVE
"This his knees any time of the sia aspirin the meeting next week mike gillislee wing miss follow on instagram at away what done that god the swoop on the butter predictive into a side so to speak out of shipping doping approach to financial data via took whether or not he could pull them despicable singapore them wunderlist total does picture skin lead me they told medieval you minutes could okay i'll say lippi those clincy came in with your brain coming you don't come guided missiles the owners may not have enough to assume that you'll make you donald mind there may be that you're such a united sevastopol pulled up quitting cgi tbi separately village brilliant young he's a few moments be the two people yup your acupuncture you'll massameh abajian intended about until we get away to give me a sequence endo dims your daily systems till you asked him to compete after that how does get when we in butter john the comply that you do nothing dental care financially to their seat in this until monday to from detained leonardo click undertaking literally give then paul told me be dampened me now.
"aspirin" Discussed on Sawbones: A Marital Tour of Misguided Medicine
"To try to figure out all the things that can do is prove i remember seeing as like you should taylor's rather heart attack and yet he like my sharjah's now you shed is a headache pill that's the first thing we do if someone comes in and we think they're having a heart attack or stroke we give him an aspirin assery away as a quick surge was continued until two thousand it's incredibly arrogant i had a really you see it's a i will say it i think it's more well known now that generally we don't give kids aspirin yeah like i said unless there's a very specific reason that your kid has some condition that we have said take an aspirin generally do not give children aspirin period under nineteen i think is the recommendation swat officers though so it is used in the prevention of heart attack and stroke it does work for for pain and fever and those kinds of things but because it is this bloodthinner because it does this other thing it may not always be the best choice for that acetaminophen does not do that so for some patients may be safer if you're on certain medications or if you have other conditions um if you're already on kind of blood centers and that kind of thing aspirin could be very dangerous for you um it can cost things like bleeding ulcers as can things like ibuprofen so if you have a tendency for bleeding or that kind of thing again there's a lot of reasons why you might not just wanna willingly take an aspirin so it's it like i say with everything you should talk to your doctor but they've even found some studies that have correlated aspirin use with a reduction in cancer risk.
"aspirin" Discussed on Sawbones: A Marital Tour of Misguided Medicine
"Over islam now there's other alka seltzer it's at same thing alka seltzer has different you know products under alka seltzer tempting with annus and ask them was just aspirin caffeine and then it grew to a lot of other things surgeons aspirin having to hurry yet although i think sedrine has other formulation like there's other pro in a like tylenol has a million different products that had same idea but yes yes uh now all of this created like this aspirin fervor fever puberty the jerk that owns fever yet fanti pareto and i love grazing anyway and uh the only thing that dampened in the fifties in the say sees a couple drugs came in the market first of all acetaminophen which he probably knows tylenol was introduced and then shortly thereafter ibuprofen was introduced and both of these cut into aspirin sales majorly because some people found them to work better and for a variety of reasons sometimes they might have been safer especially tylenol for various patients um the other thing that really put a damper on aspirin sales was rise syndrome reis and drum eh did you ever here don't take aspirin if you have chickenpox have you ever heard that a lot of people may have kinda that they knew that but they didn't know why they knew that any 80s this rare complication was found in children who were given aspirin while they were recovering from certain vine viral illnesses chicken pox is the one that gets the most press but really was just any kind of viral illness they had a fever they feel bad they were given an aspirin and they developed this inflammation of the brain inflammation of the liver very serious illness that sometimes could have been fatal i'm just a small number of children but enough that they're grew this concern why is there this reaction in kids who get aspirin with certain viruses we all know but the point was be careful don't give aspirin to kids was what grew out of this concern period of his agenda box don't give aspirin to kids grew out of this over unless for a very specific reason you're doctors told you to give your kid aspirin don't give you could aspirin hooker is a good rule of thumb.
"aspirin" Discussed on Sawbones: A Marital Tour of Misguided Medicine
"To some extent then your blood so so using aspirin four bleeding brad is not a good idea of her but all those other things well unemployed or either but anyway i could see where they got some of these ideas because it they're probably was some response from the will of arc hippocrates advised powdered willow bark for headaches and also for minor aches and pains and fevers and the same kind of thing everybody had been using it for in addition he specifically had a recipe for a kind of tea made of willow bark the he recommended you give two women during labour to help with labour pains surf somebody is having a baby you can give that person some will embark t what was called anything to you already dude boiled leaves or lease right now right if a battle of his of his hot water battles on that on that 50s menu that we saw at that cosi place today we the boiled leaves his was the like fifty slang for t the while ct kuwait like if you want if you are slamming yet diner saying if you want if you want black coffee with sugar you say i wanna brunette with sand ochre and if you went t jesse jackson boiled leaves which would make you not want t i think i would change my order if somebody said all you want boiled leaves i go no grooms you're an extra so it's wellknown throughout the roman were all that by then that you should use will embark for things and anything whistle asleep in them plenty wrote of the eu's plenty of the elder word of the use of willow extensively and natural history including chapter thirty seven which is called the willow fourteen remedies hm so at least fourteen remedies tougher each one of these i is different in terms of what you add to it so willow plus alcohol for instance is great for us killing your libido okay so if you need to do that if you want to lessen your sex drive willow bark alcohol.
"aspirin" Discussed on Sawbones: A Marital Tour of Misguided Medicine
"Every every plant the contains that you got to wonder about its bioavailability like how much of it can you absorb based on how it is two thousand pecan comparison so i mean if you wanna eat two thousand peas i'm not going to stop you would stop me incorrect without without view immunity that peace are very small to be fair so you're saying review got jeffy ilk i never considered out ever considered veterinary mp's by the individual yuda as like how many figure out at you you're a guy do chicken to lose 50 ap's thought the and that doesn't sound like very many you say fifty ap's and i think that's probably a very small amount of fees at all hours never considered the amount of luxury hills also degrees over your very hard to calculate calorie gunter so so in all of these mentions of the use of these solicit late sal soak out senseless late amusing these words interchangeably containing plants it usually used for pain or for fevers that usually howitt's referenced as as being you know employed as a medicine aged chinese medicine also advised willow bark specifically for a variety of illnesses like i said pain and fevers also things like romantic fever specifically a goitre they recommended willow bark for a colds probably because of the a and pains and fevers and all those things that came with it and even bleeding which was probably a bad idea because as we're going to talk about aspirin does.
"aspirin" Discussed on Quirks and Quarks
"So it's like taking an aspirin venue of an infection you'll feel better about you have an solve the problem however sometimes staking the aspirin is really useful and necessary in order to give us perhaps a little more time to undertake their massive decarbonisation that we need to do in the world to reduce the emissions to zero and to get the carbon concentrations down from the atmosphere what's to stop a country countries are individual from unilaterally deciding to use these technologies now were in the near future at the moment there is no international law that would prohibit this so in in reality anybody could undertake this anybody who has the technology to get a few planes up into the stratosphere and in fact this is the single largest problem we see in terms of potential dangers and that is the unilateral ungoverned deployment of solar engineering for all countries were able to agree on doing or not doing such a deployment than it would be much easier to take care of whatever negative impacts might happen afterwards if they were to happen at all how likely as at that spread equally benefit all regions of the world what computer models show to us is that the higher temperature reduction one would like to get the more likely that there will be different regional negative impacts coming up in other words you will always have a global benefit of reducing the temperature but the more temperature you want to reduce the more likely is that certain regions of the world will have.