29 Burst results for "Ard W"

"ard w" Discussed on KOA 850 AM

KOA 850 AM

02:37 min | 5 months ago

"ard w" Discussed on KOA 850 AM

"Tell your smart speaker to play K away on I ARD radio. Let's go inside. The numbers presented by first Reverse mortgage U. S. A. Well. Last night's temperature at first pitch was 98 degrees here at Coors Field record. First pitch temperature for a game here at course, field. Was back on June 25th of the 2012 season, the Rockies hosting the Washington Nationals, and it was 100 degrees at first pitch. Bring all this up because even with those high temperatures, the Rockies have never played back to back games where the temperature has been 97 or above. I think that's going to end tonight, but we shall see you when we get that first pitch temperature coming up here in a few minutes inside the numbers presented by first Reverse Mortgage USA know the facts for your peace of mind. At one s t mortgage dot com. Our window of opportunity concerns the hottest hitter in baseball right now, Vladimir Guerrero Jr. The 22 year old slugger for the Toronto Blue Jays. After a good rookie season had kind of fallen off a little bit. And after the short and 2020 year, people were saying, Well, I don't know if Vlad Jr is going to be All that was advertised well, After hitting 2 62 with nine homers in 33, R. B s in 60 games last year he's already hitting in 64 games this year. 3 46 with a major league leading 22 home runs and 56 R B s. The big guy has really been good. And if you want to get excited about something He says he's open to participating in the home run Derby when it takes place in a couple of weeks here in Denver, is part of the All Star game activities. That could be really fun to watch the window of opportunity brought to his by lifetime windows, inciting Denver's most trusted windows.

100 degrees June 25th Denver 98 degrees 33 64 games Toronto Blue Jays Vlad Jr 60 games 2012 last year Coors Field 97 nine homers Washington Nationals first pitch Rockies tonight this year 2020 year
What Are the Quirks That Come With Being a Developer

CodeNewbie

02:09 min | 6 months ago

What Are the Quirks That Come With Being a Developer

"Let's start with you telling us about your coding journey. Where they're all begin for you. I i started getting into coating during college. I started out as a psychology major and was pretty intent on finishing up. Undergrad getting a master's degree and being a counselor About couple years into it. I realized i liked the more hard science a lot. Better than sort of the sop science and social science part of it. And i had taken a statistics class. Like just a psychology stats. Class really looked to that. So i got into statistics and changed my major to that and at that point i had to take a bunch of like stats computing type glasses. So for instance statisticians tend to use programming languages like our or sass or even just like sql database management. And so that was really my first introduction to programming at that point. Like i realized if i to look at the t. between statistics and computer science actually like program a lot more than i liked the stats part of it. Nah i landed up graduating with degrees statistics. During that time. I just did a ton of learning on my own. Did a lot of like could academy courses recode cam fluoro- site videos whole time. Packer rank exercises. I even read through twenty programming textbooks now on just java script html and just building stuff just trying to make little side project snack things together. And after i graduated from college. I landed my first programming job. So what was it about that stats class. And then getting into programming. That resonated with you so is taking ard says stats programming. Which are and it was really amazing. Nina we could like run simulations and experiments just for typing a few lines of co dried. We could run simulations of very simple things like let's flip the coin hundred times and see how many times it lands heads or tails or even just like data visualization like we have data set and using just a few lines of code. You could use like a stats package like something like g plot to create this beautiful chart. That was really cool that you could like essentially build something out of basically nothing

Undergrad Packer Nina
"ard w" Discussed on New Jersey 101.5

New Jersey 101.5

01:57 min | 11 months ago

"ard w" Discussed on New Jersey 101.5

"Henry Little ARDS another life weekdays. We talk weekends. We rock. It's a big Joe House party. Taking your party hit. Request the dedications 1 802 83115 or make them on a rapid New jersey with 1.5 Facebook and chat we've gets covered. Amar has to your house. We need a little party. Nobody does it better. Thanks so much for joining us. We appreciate it. Well, it's finally here. It's Girl Scout Cookie season. Yeah, and and a new report of found that legal legal marijuana. Brought in more money. Last year than Girl Scout cookies did No to be fair Girl Scout cookies wouldn't have made his much money if it weren't for marijuana. Gotta tell it like it is here is fast traffic. Well on to 95 north and sweets. Burrow right lane closed for overhead sign repairs, but we never had 14 and 15 White Horse Pike Down. Poland. Wires cleared eastbound past 2 95 but westbound We still have the right lane closed. This will be just between Gloucester Pike and 2 95, and we've got a crash on the Garden State Parkway Express lanes North bound approaching 1 20 Aberdeen. The left lanes closed Route nine State of the Union Hill Road to Manalapan. The off ramp is shut for roadwork and 1 30 North Construction Clearing Ridge Road up toward fresh Pond Road in South Brunswick. At least it's scheduled to clear now. Across the Hudson leaving New Jersey were good. This report sponsored by Unbound out or GTA girl in Kenya, dreams of becoming a doctor and altering Guatemala. Dreams of being part of a community reach out and change their world. It will change your own unbound adored traffic every 15 minutes. Next report 9 18 on New Jersey one a 1.5. New Jersey 11.5 wants you to start the new year with some new moves. You could win a free three month membership to Planet Fitness Plus getting on our grand prize of $1000 a fresh, delicious meals from Eat clean, bro. Listen, we tasted 9 15, 1,.

New jersey marijuana Joe House Facebook Henry Amar Manalapan Poland Kenya South Brunswick Aberdeen Hudson Guatemala
"ard w" Discussed on KNST AM 790

KNST AM 790

01:54 min | 1 year ago

"ard w" Discussed on KNST AM 790

"ARD radio station. Calculations imminent on Jack Keller him Fox years, perhaps as soon as early next week after an advisory panel of the Food and Drug Administration recommended the Fizer Corona virus vaccine for emergency use in the U. S supplies will be scarce it first. But Alex is are the health and human services secretary. Said 20 million Americans could be vaccinated within several weeks. The Centers for Disease Control and Prevention will meet this weekend with its ruling on the vaccine. Fox's Caroline Shaw, lively another 224,000 cases of the virus, reported Thursday in the 1st 10 days of December. More than 24,000 deaths have been blamed on the virus. It will not be a coronavirus economic relief deal until next week at the earliest. And House speaker Pelosi says it may have to wait until after Christmas, Louisiana Congressman Steve Scalise says every day of delay hurts more of the people who need the help. The most small businesses don't have the time to wait on a new president or some political game by the speaker. Before they make a decision on whether or not they will close for good. Then it needs to add its approval to a House passed stopgap spending bill today or the government spending authority could expire at midnight. Before states being sued by Texas in the Supreme Court for changing the election procedures have filed their responses to the lawsuit asking the justices not to hear the case. But Texas attorney General Camp Paxton tells Fox News of Nice is a really important case, not just for this election, but it sets the standards for how our elections are going to be in the future. Whether we're gonna have the opportunity of Elections that we count on that We trust magazines, persons of the year for 2020, Joe Biden and Kamila Harris, the magazine CEO, saying they offered restoration and renewal in a single ticket. Leaders of the European Union of voted to cut their greenhouse gas emissions by at least 55%. By the end of the decade. America.

Fox Jack Keller Centers for Disease Control an Congressman Steve Scalise Food and Drug Administration Texas Fox News Joe Biden European Union Supreme Court Alex Caroline Shaw secretary General Camp Paxton president America
"ard w" Discussed on KNST AM 790

KNST AM 790

01:55 min | 1 year ago

"ard w" Discussed on KNST AM 790

"High ARD radio station. Another member of President Trump's inner circle has the coronavirus. I'm Joe Chiro. Fox News President Trump says his personal attorney, Rudy Giuliani, has tested positive for covert 19. Giuliani has traveled extensively recent weeks in an effort to challenge election results and several states lawmakers continue to consider more covert relief for those struggling amid the pandemic. The latest hopes around a $908 billion bipartisan proposal recently unveiled Illinois Democratic Senator Dick Durbin. My prayers will be answered if it does, but we've got a few remaining issues. I think we can work them out. And if we can bring this forward, I just hope that Senator McConnell let us bring this matter to the floor as quickly as possible. We have a lot of work to do, and just a few days to do it there been on a bee sees this week, millions of Americans are poised to lose pandemic unemployment benefits set to expire December 26th. Two crucial Senate run outs and Georgia are drawing the focus of members of Congress. The result could shift Senate control in a Biden administration on Fox and friends. Georgia GOP Congressman Doug Collins said. The stakes are high. This is not just to Senate race in George, this is about actually changing the direction of the United States. Senate President Trump Rally for Senators Kelly left her and David, Purdue and Georgia Saturday while making unsubstantiated claims that fraud cost him the general election functions. Grenouille, Scott Leffler and Democratic Capone. Raphael Warnock Debate tonight at seven o'clock on the Fox News Channel, a brief scared of Georgia College campus. Kennesaw State University says normal operations can resume after the school told students on the Marietta campus to hunker down because of an armed intruder. A short time later, the university tweeted that the suspect had been apprehended. And there's no threat to either case. U Campus Marietta is just northwest of Atlanta. America.

Senate President Trump Georgia Rudy Giuliani Senator Dick Durbin President Fox Joe Chiro Kennesaw State University Senator McConnell Fox News Channel Georgia College Raphael Warnock Illinois Doug Collins Atlanta United States GOP Congress Marietta
"ard w" Discussed on WSB-AM

WSB-AM

02:21 min | 1 year ago

"ard w" Discussed on WSB-AM

"93 wife. Months. There is one in white that's fantastic. Currently in the United States, 8.2% of ice cream machines in McDonald's or currently broken, which seems like a low number to me. Just 8% a lot of McDonald's. There are by city the most broken machines by city Philadelphia. 15.6%. Okay, I guess they had some rioting yesterday that might have time to do that. Santiago. It's journals. It's a German word for the way out. The 13.6% not working San Franci. Easy 13.3% that the California McDonald's. They're not working. Los Angeles 12.5% are not working. BOSTON 11.11% not working same with San Jose Houston, Texas Longoria 10.5% of the ice cream machines. They're not working just under 10% in San Antone. Seattle. They're all working McDonald's workers make like $23 and Alice. True, Make sure they're working. It's crazy out there. There's no tipping in restaurants. I mean, you can do tips, but the waiters make AH, high high salary right and they build that into the bill. So there you are. There's no tipping anymore. It's kind of like Europe. I guess that this surprises me in New York only to 0.1 per 7% of the Ask. Machines are not working at McDonald's in New York. This is fantastic. One of the three indulging currently out by the way, if you're going to Dalton right now, the one on terrible of ARD at Mount Zion Road, that ice cream machine is not working. I could. I could do this for four hours. People just call up. Hey, Is it working the one on flatulence road just inside to the five not working. I'll do it. I'll do it all day one more second ago of the Mark M show. Sent 49 Corday carrier WSB 24 hour Traffic center. New Trouble to Cap County I 20 westbound Evansville Road exit 74 Left Lane is blocked there. That's causing delays. Still seeing brake lights very heavy through downtown for 100, Slow south of Lennox connectors. Outbound jammed up 17th street down toward I 2020 westbound West Freeway slow leaving 25 out toward the six Flags area due to fright. That's lots of people heading over that way that's slowing 25 north and South bound intern our troops on the west side of town. This report brought by BP and PAY Atlanta Fill your tank with Amoco Ultimate with immigrate and keep on going. Amoco Ultimate with invigorate at BP and Amoco stations. Alex Williams 95.5 WSB candidates.

McDonald Amoco Ultimate BP San Antone San Franci United States New York Mount Zion Road Los Angeles intern Europe Seattle San Jose Houston Santiago California Alex Williams six Flags Philadelphia. Longoria Dalton
New Zealand's Jacinda Ardern wins second term in election landslide

Ask Me Another

01:02 min | 1 year ago

New Zealand's Jacinda Ardern wins second term in election landslide

"In New Zealand resounded Lee handed Prime Minister Jacinda ARD earn a second term in today's national election. NPR's Julie McCarthy reports are Dern's handling of the Corona virus pandemic helped to secure a rare landslide victory for her center left party. With most votes tallied. Prime minister are Dern's Labour Party is projected to win an outright majority of parliamentary seats, making it the first party to govern alone in 24 years are Dern's go hard and go early approach to the pandemic helped crush the virus in New Zealand and propelled her party to victory are Dern's trademark empathy and compassion were the accelerants. In a powerful speech that emphasized the need to see each other's perspectives and an increasingly polarized world are durn reached out with an inclusive Val. We will not take your support for granted. And I can promise you we will be a party that governs for every New Zealand A Julie McCarthy, NPR news

Dern Julie Mccarthy New Zealand Prime Minister Jacinda Ard Labour Party Prime Minister NPR LEE
Daniel Prude: New York black man died after police pinned him down

Nightside with Dan Rea

00:46 sec | 1 year ago

Daniel Prude: New York black man died after police pinned him down

"In Rochester, New York, after revelations that a black man who reportedly suffered from mental health issues died After being in police custody several months ago. Here's ABC is Mark Millar, Rochester police video shows Daniel proved with a plastic hood over his head as he's handcuffed and pinned to the ground by officers. The hood apparently to control his spitting prudes movement eventually slows and he died seven days later. Mayor. Lovely Warren says the incident back in March is only coming to light now, so the investigation could proceed breaks my heart as well. But we have to follow the process. Both Warren in the city's police chief blamed New York's attorney general for why the case hasn't moved forward. Mark Criminal ARD ABC NEWS NEW YORK, The New

New York Rochester Mark Millar Warren ABC Mark Criminal Daniel Attorney
Christchurch mosque attack: Brenton Tarrant sentenced to life without parole

All Of It

01:15 min | 1 year ago

Christchurch mosque attack: Brenton Tarrant sentenced to life without parole

"Zealand has sentenced the white supremacist who shot dead 51 Muslim worshippers in Christ Church. Life in prison without parole. It's the first time the sentence has been imposed in the country. Sentence was delivered by Judge Cameron Manda, who said the gunman, Brenton Tarrant, was devoid of empathy for his victims on each of the 51 charges of murder charges. 12 51 Was sentenced to life imprisonment. Order that you save the sentences without parole. On each of the 40 charges of attempted murder charges. 52 to 91. Your seat is two concurrent terms of 12 years in prison. The charge of committing a terrorist act, charge 92. He was sentenced to life in prison. New Zealand's from minister just in tow ARD and said she hoped the killer would now never be mentioned again. The trauma of March 15 is not easily healed. Today, I hope is the last Where we have any cause to hear or utter the name of the terrorists behind it. His deserves to be a lifetime off, complete and utter silence.

Brenton Tarrant Judge Cameron Manda Zealand Murder New Zealand Christ Church
"ard w" Discussed on WNYC 93.9 FM

WNYC 93.9 FM

06:30 min | 1 year ago

"ard w" Discussed on WNYC 93.9 FM

"You know, Heather did he Since he lived to tell the tale Unlike poor Kristen or kiss his father, did he have a political change of heart? Was he a trump supporter and came out feeling betrayed by Trump from his covert experience or people around him, if you know I'm not really sure it's a very interesting question. I mean, you know, and right now. I know, for instance, personally, my father in law is a very huge from fan He's down in the village is in Florida, and you know he's really not buying into any of the covert stuff either. And, you know, obviously my husband is very concerned because he hears him. I'm going out to dinner. I'm doing this. I'm doing that and he's going to be 80 in December and has some pre existing conditions. But you know, at the end of the day, he's an adult. He couldn't do what he wants. But obviously my husband and I are very concerned about that. Heather. Thank you So much for your call. We really appreciate your story on DH your contribution so as college from NPR replayed that Kristen or Kisa clip. A lot of people are citing that today for its power. Anyway for you is a political correspondent to tell if it resonates with enough people that there are clusters of stories like that. I mean, it's so hard to know, but I mean, I think what Jimmy did feel, though particularly powerful about that moment that Christian gave is, I think a lot of us journalists were staying, and we were sort of skeptical right of the nature of how a virtual convention would really come across because it's so fundamentally different than a big, large scale arena, which hearing crowds To me. They're the Christian moment struck at what you can really do that powerful with a virtual convention, you know, almost instantaneously. I saw that moment being shared on social media. And it's a moment that usually go viral and be terrible because, you know, we just heard from one of your listeners. There are people who resonate with her story who have similar experiences and And we do know that that the president's response to the pandemic when we look at polling, he's not doing too well and anecdotally, you know, I did some reporting myself recently in Florida and I heard from Republicans who have not been thrilled. With how he responded to the public health crisis at this point in time. Judy in Brooklyn has a story of I think herself Judy around W N My C thanks for calling. Head out. Hi, Judy. You're on the air. Yes. Oh, my God. I want to tell you something. I'm trying so long to get through with you. I always listen to you guys in my kitchen and you're so wonderful. I want to tell you I am in this country 20 year walking every day and health care and never take a day employment. But this virus rip us apart and it's such a shame to see what this president is doing. I had two virus real bod. Thank God. Ginger, You know, lemon like local Stop, help me and I listened to that door last night to lose our father. It's such a shame on I want to do something. Chris Cuomo. He is such a good guy. I listened to him on CNN and you know, he had a virus read about And the convention was so nice. It's such a nice thing to hear about Joe Biden. He's don't tow ARDS Goodman. And he is so nice to all the people in the train, and I just can't explain, And he's so experienced like Hillary Clinton. And Obama and his wife. They're such a good people. Chuck Schumer, Nancy Pelosi on most of our field more freeze in your George. He's a good man. I get it so nice. So it doesn't sound Judy like You got the virus, partly because you believe the president's hype. It doesn't sound like you're like you're someone who was inclined to believe Trump in the first place or a digit I didn't get you. Did you? Do you feel like you got the virus at all? Because you bought into Trump downplaying it at the stars. You sound like a trump skeptic in general. Go ahead. Yeah, I didn't take it serious because how he was doing, you know, And in April, I couldn't move peeing on my chest. I had it real bad attacks, right? Not to go to the hospital, you know? My son had it real bad. Miss Postlewait is violence is not the plating and this man Doctor cares Not if you know what you don't stand in billions of dollars building wall. I can spend money on a virus. We don't have gloves and mask and nothinto worked for in medical field in New York on this man is wrist and money on building that while I'm telling you're putting Children in cage We need to get out of here. He's such a disgrace. You know, Judy, thank thank you so much. Thank you for your call. I'm glad you I'm glad you got through to the show. Please call me okay. Can you please I really want to talk to Chris Cuomo about the virus because I'm having some problem that they don't want to tell you, but I don't know how to get to him. Well, you know, maybe you should get to a doctor. Now we could. Ah! Give you some. I don't. I don't have contact information for Chris Cuomo. Ah, who's never been on the show, But, um, if you need You know, a medical referral. Um, we could take you off the air and see if you need help In that respect. I can't get through to Chris Cuomo. You'll just have to contact CNN for that. But Judy, hang on if you want, and somebody will try to get you some Some other kind of contacts. If you need some, you know, some medical referrals or something of that sort. But Judy thank you very much for your call and with asthma, Hollywood NPR political correspondent as well before we move on from the Kristen or keys, a story to some other things from last night. I mean, each convention will have its personal higher stories, right? I watched some of the post convention coverage on Fox last night, and they were emphasizing that the Democrats didn't even talk about street crime or Political violence where where it has occurred, and and they showed a clip of a guy being beaten by a crowd on the street. In Portland, a video that's gone viral online..

Judy Chris Cuomo Kristen Trump president Heather CNN Florida NPR Joe Biden Hillary Clinton Obama Chuck Schumer Jimmy Ginger Goodman Miss Postlewait
"ard w" Discussed on KNST AM 790

KNST AM 790

03:32 min | 1 year ago

"ard w" Discussed on KNST AM 790

"ARD radio station, sharing the spotlight for the first time. I'm Lisa let Sarah Fox News presumptive Democratic presidential nominee Joe Biden and his newly selected vice president, Senator Kamala Harris, appearing together this afternoon, and Delaware, Biden slammed the Trump administration, saying the president cares more about himself. Now on their side. That's going to change an abiding Harris administration, Senator Harry It's also coming out swinging. You don't have to accept the failed government. Of Donald Trump and Mike Pence. In just 83 days. We have a chance to choose a better future for our country that you appear feet apart on the stage of a high school and I just a handful of reporters in the room. Judith Pandemic President Trump using today's briefing to cover a wide variety of topics, including taking aim of Democrats for the lack of action. On a new round of Corona virus relief. The president began by recognizing stock market gains, then segue Wade into criticism of Democratic leaders Chuck Schumer and Nancy Pelosi holding the American people hostage over money for their radical left wing agenda, he said. That includes billions for mail and voting, he says without specifics is rife with fraud. As for covert numbers and hot spot states, the president said, it's greatly improved some with very little, if any problem. Large portions of the United States. He again called for schools to re open, saying young people can fight off the virus. Much better. Colonel Scott Fox News All Street that our attitude 89 points the NASDAQ Up to 29 the S and P plus 46 points. America is listening to Fox News. A new lawsuit. I'm John Klein. Kunst News Arizona Water Park Golf Land. Sunsplash says They are filing suit against governor Doug Ducey for specifically targeting the company and forcing them to shut down while hotel water parks and other similar facilities were allowed to stay open. We've lost market share. Because those businesses being allowed to continue to operate. It's a clear violation of equal protection in our opinion. General manager Steve Carlston says the appropriate authorities knew that these other water parks were still operating yet they were never asked to close. The Arizona Daily Star says the final practice run for the Oh Cyrus Rex team has done and everything went according to plan on October 20th. BU Arizona Let asteroid sampling mission will touch down on the asteroid Bennu collect over £4 of dust and small rocks and is scheduled to return to Earth on September 24th 2023. I'm John Klein Kunst am 7 90 Tucson's most stimulating talk. This report is sponsored by lows. From the casino del Sole, The soul of Tucson Traffic Center. Gotta crash on Benson Highway and Alban on watch for another crash. Old Veil Connection Road right, a country club, and there's a collision as well on Oahu in 12th Avenue. And some kind of obstruction on the roadway just used some caution. 22nd Street just west of Kino Parkway. I might car that is traffic. Election Day is.

vice president Senator Kamala Harris Chuck Schumer Joe Biden John Klein Donald Trump Trump President Senator Harry It Arizona Water Park Golf Land Arizona Daily Star Sarah Fox Scott Fox Fox News Delaware United States Kino Parkway Mike Pence Lisa Doug Ducey
"ard w" Discussed on KOMO

KOMO

04:59 min | 1 year ago

"ard w" Discussed on KOMO

"Hamill ARD ABC news More and more retailers now require you to wear a mask when you enter their store. So who's responsible for making sure you're wearing one? That question has caused lots of debate. I spoke with Kimble wear who's covering it. All for The Washington Post came at least one labor union representing retail workers is very concerned that too much of this burden of enforcing this policy is on them. That's right, the retail Wholesale and Department store union, which is one of the largest in the country, that represents workers. You are in industries like retail grocery food processing. It expressed some concerns that with the growing number of states that have masked mandates and the growing number of brick and mortar stores that have store policies requiring masks The responsibility to enforce these policies, which are probably safety is falling to the workers and the response from a lot of customers, at least as we've seen from Different news reports and viral videos can be somewhere between frustrated and annoyed, too violent and even deadly, in some cases, So what is it that the union would like to see retailers do about this? The union is asking for stores to make this responsibility, something that is entirely contained by baby outside security, or at least management. They argue that other other kinds of security measures are typically under the purview of other of other employees that the store hires that the company hires and you see this as something that puts Workers on the front lines, You know, also pointing out that if customers aren't wearing masks that's putting the worker risk. Most of the workers are masked up, and that's helping the customers so they also don't want to be. In direct contact with these with these customers. If they don't want to follow the policy, creating that kind of equation, though, there's a cost there in many retailers just aren't generating as much cash as they did pre pandemic. Yeah, I think that's something that definitely is is an issue, although that was not cited as a reason for not going through with this. I reached out Several major retailers, including Trader Joe's and Home Depot, and they didn't bring up cost as a reason. They didn't say whether they would or wouldn't do it. But one of the overall kind of takeaways that I got from Of the big corporations that have these masked policies now is that there's just too higher risk in really being hard on the enforcement. And that was the other part of the concern from the union is that even if stores have these policies they're not always enforced very stiffly on DH For so many of these corporations. They've just made the calculus that it could simply be too much of a security risk. There. Was there any since this could be settled in a regulatory setting or even the courts. That I'm not sure of. You know, I didn't talk to any regulators. I'm not sure what's been done in other countries. But, you know, in countries just I know anecdotally. Like South Korea, they have kind of specialty employees, You know, forces that are In charge of doing some of these different things like checking your temperature when you come into the dining room at a restaurant and making sure that I've already comes and has a mask. I don't know that that's something we've seen widely in the U. S yet, but definitely something to keep an eye out for that's Kimble Wear, read more online at washingtonpost dot com. The Corona virus brings change and more change Two trains in Italy. Italy moves to ease social distancing on train travel on Ly to quickly reversed the decision as covert infections ride maybe sees Megan Williams of Rome, where, after months of wide these basic passengers on Italy's highly used trains, train companies had announced they were lifting the restrictions. Trains would once again returned to filling up all seats. But health experts here expressed alarm at the move, prompting the government to reverse the decision Implementing once again alternate seating. The decision comes as Italy's low rate of daily covert infections has been rising slightly again after hovering around 200 a day. Italy was the hardest hit Cove it country in Europe, with icy units overwhelmed by patients at the peak of the outbreak in February and March, But it's now one of the world's biggest success stories and fighting Covad. For more than two months long, locked down social distancing and required mask wearing indoors. Daily deaths are now down to under 10. Megan Williams ABC NEWS Rome Your money at 20 and 50 past the hour on Comeau News. Your coma propel insurance Money Update with Jim Tesco. Despite the uncertain economy and as still spreading Corona virus, the stock market continues to power higher. For the month of July, The major indexes rose between 2% in the case of the Dal industrials, and 6.5% in terms of the tech heavy NASDAQ composite the coming week will be another busy one for economic data. Expect updates on US manufacturing and services sector, June factory orders and, most importantly, the July jobs data. Pandemic has not only meant a boon for online.

Italy Department store union Megan Williams Kimble ABC Hamill US South Korea Home Depot Trader Joe Rome Jim Tesco The Washington Post Covad Europe hit Cove Comeau News
Why An Experimental Therapy for Inflammatory Disorders Could Help the Fight Against COVID-19

The Bio Report

06:04 min | 1 year ago

Why An Experimental Therapy for Inflammatory Disorders Could Help the Fight Against COVID-19

"Joe. Thanks for joining us. Joe. Thanks To be for here joining thing us. we're going to To talk be here about thing Aqua Lung Therapeutics we're going to talk about Acute Aqua Respiratory Lung Therapeutics Distress Syndrome Acute or arts Respiratory Distress and your Syndrome efforts or to arts develop a treatment and your for efforts this condition. to develop a treatment Let's for start this condition. with ours though. Let's What start is with it ours and though. how big What a health is challenge? it and how Does big it represent a health challenge? Does it represent about half a million people. about Every year get half air a million people. F- Every Acute year Respiratory get Distress air Syndrome F- Acute Respiratory in the Distress United States Syndrome alone. And in you know the United close States to alone. two million. And Maybe you know globally close to two million. so it's Maybe globally it's not a so uncommon it's it's not a uncommon Disorder Disorder But it is a extremely But it is challenging a to extremely treat disorder challenging because mortality to treat of this. disorder because mortality Anyone that of this. had gets a yard Anyone that had is gets Thirty a yard to forty percents is In Thirty the US to forty and percents it's probably In the higher US and it's probably Outside the US higher what Outside makes the it US so challenging to what treat? makes it so challenging Well to treat? it's It's sort Well of the ultimate it's in inch It's sort of in the ultimate the stress in to inch in the To stress to a human being To in that a human being They have in that multiple They attacks have on multiple attacks a variety of on Oregon a starting variety with of the Oregon lung though starting the the most with the common lung causes of though ARD the the s most are common causes sepsis of ARD which is s infection are in sepsis the bloodstream which is infection and trauma in the bloodstream and and trauma Smoking and elation will do it Smoking and elation will do that it Curiel and and viral pneumonias that Curiel and so and viral as pneumonias a result the and starts so off as with a inflammation result in the the lung starts from off those with inflammation particular in the lung from those Causes particular the Causes inflammation becomes the waves inflammation waves becomes of amplify waves waves inflammation of amplify that starts to affect inflammation other organs. that starts Like to your kidneys affect and heart other organs. Like and your ultimately kidneys and patients heart with AIDS and wind ultimately up. patients They with don't AIDS survive. wind up. They die from They that don't survive. multi organ They failure die and from that that multi he's organ organs failure and that weren't he's able organs to sustain the weren't able inflammatory to sustain injury the we've inflammatory heard a lot about the respiratory injury challenges we've heard that a lot can about occur the respiratory to people challenges infected that can occur with the to covid people nineteen infected virus with the are covid nineteen the ones virus who end up on are respirators the ones suffering who end up from on respirators arts and suffering what from role arts does arts and play in what the role mortality does arts of play patients in with the mortality Covid nineteen of patients with Covid arches nineteen probably the primary arches probably cause the primary of death in most cause of the cove in of nineteen death patients. in most of At the least cove in nineteen that's what patients. the the At least reports from that's China what the and the elsewhere reports suggesting from China and elsewhere suggesting Covid NINETEEN INDUCE. Cards Covid NINETEEN INDUCE. has a Cards lot of similarities to has a garden lot variety of similarities area to garden variety but it area also has some unique but it also changes has some that unique changes that may that not be typical. Air that may not S. as be well typical. Air and S. as well The ventilator and The ventilator Think this is an important Think this part is an important of the story. part of the That story. patients with That patients With Kobe with nineteen viral With infection Kobe nineteen or viral other causes infection of or other causes Respiratory of distress like I mentioned Respiratory substance or distress bacterial like I pneumonia mentioned substance trauma or bacterial and pneumonia you have trauma Increasing respiratory and you have distress Increasing respiratory your lungs. Start distress to fill with Lewis your lungs. Start to and fill with Lewis the work of breathing and when your the work lungs are. of breathing Our when full of your fluid lungs is are. very very Our full of fluid rate. is very very So these patients rate. generally run So out of these patients generally Energy run out of the fatigue Energy and they need then the fatigue later to help and they need then with later their respiration to help with and their so respiration the the and the so the the the irony the of of the this is that irony the ventilator of of while saving this your is life that the ventilator while because saving your your life new patients for an out because of your energy new patients agreed on for an their out own of energy agreed then on later their own also the major then later cause also for information the major as well. cause for information That's been as known well. for now sometime That's and been known for so now strategies sometime to and address so strategies a yes to whether it's address cove nineteen a yes induced whether or it's otherwise cove nineteen induced need or to take otherwise into account the fact that then need later to take contributes into account to that the fact inflammatory that then later burden contributes patients to that with they inflammatory burden patients with they as an academic. You've done functional as an academic. You've done functional genomics work that identified candidate genes that contribute to inflammatory disorders. Such as arts this led to a focus on the NAP. Jean what is Napkin? And what role does it play in the inflammatory cascade? Yes well that's That's exactly right. Dan we Early on when I was a cheap home area at Johns Hopkins the New Year early. Two thousands we are group there. through clinical trials that was published in the New England Journal in this clinical. We identified the fact that the later contributed some mortality in they already s and and the hypothesis was that the way that Ben later contributes mortality. It was it was causing excessive increases in inflammation so at that point my laboratory My Research Laboratory at Hopkins we We've again focusing very Aggressively on trying to identify genes. That might be involved in. How the ventilator induced that inflammation and This is how we found that gene. That's called NAM. Nam stands for nicotinamide Fossil Rizal Transfer. A is a protein that has a normal function inside the cell. But when it's secreted from the cell floats in the bloodstream. It is a very potent planetary mediator. And the reason we think NANCE's A pretty novel target for then later induced lung injury and they are s in general including cove in nineteen induced area. Is that this. Gene is induced very early. It's one of the first genes induce patient or a animals exposed to Mechanical Ventilation is this unique to the lungs or is this across inflammatory

Arts Respiratory Distress United States Aqua Lung Therapeutics Covid Covid Arches Gene Oregon JOE Lewis Joe. Aids Kobe China Nance Nicotinamide Fossil Rizal Tran Curiel Mechanical Ventilation Induce. Pneumonia
Why An Experimental Therapy for Inflammatory Disorders Could Help the Fight Against COVID-19

The Bio Report

04:46 min | 1 year ago

Why An Experimental Therapy for Inflammatory Disorders Could Help the Fight Against COVID-19

"As a researcher Joe Garcia Applied Functional Genomics to understanding genes that contribute to inflammatory disorders such as acute respiratory distress syndrome or arts as founder and CEO of the Biotech Company. Akwa Lung Therapeutics. He's working to advanced therapies to hit these novel targets to treat unchecked inflammation with the company's lead experimental therapeutic candidate targeting arts. We spoke to Garcia about the company's arts. Therapy how it works. And why it's time we focus given the cove nineteen pandemic Joe. Thanks for joining us. To be here thing we're going to talk about Aqua Lung Therapeutics Acute Respiratory Distress Syndrome or arts and your efforts to develop a treatment for this condition. Let's start with ours though. What is it and how big a health challenge? Does it represent about half a million people. Every year get air F- Acute Respiratory Distress Syndrome in the United States alone. And you know close to two million. Maybe globally so it's it's not a uncommon Disorder But it is a extremely challenging to treat disorder because mortality of this. Anyone that had gets a yard is Thirty to forty percents In the US and it's probably higher Outside the US what makes it so challenging to treat? Well it's It's sort of the ultimate in inch in the stress to To a human being in that They have multiple attacks on a variety of Oregon starting with the lung though the the most common causes of ARD s are sepsis which is infection in the bloodstream and trauma and Smoking elation will do it and that Curiel and viral pneumonias and so as a result the starts off with inflammation in the lung from those particular Causes the inflammation becomes waves waves of amplify inflammation that starts to affect other organs. Like your kidneys and heart and ultimately patients with AIDS wind up. They don't survive. They die from that multi organ failure and that he's organs weren't able to sustain the inflammatory injury we've heard a lot about the respiratory challenges that can occur to people infected with the covid nineteen virus are the ones who end up on respirators suffering from arts and what role does arts play in the mortality of patients with Covid nineteen arches probably the primary cause of death in most of the cove in nineteen patients. At least that's what the the reports from China and elsewhere suggesting Covid NINETEEN INDUCE. Cards has a lot of similarities to garden variety area but it also has some unique changes that that may not be typical. Air S. as well and The ventilator Think this is an important part of the story. That patients with With Kobe nineteen viral infection or other causes of Respiratory distress like I mentioned substance or bacterial pneumonia trauma and you have Increasing respiratory distress your lungs. Start to fill with Lewis and the work of breathing when your lungs are. Our full of fluid is very very rate. So these patients generally run out of Energy the fatigue and they need then later to help with their respiration and so the the the the irony of of this is that the ventilator while saving your life because your new patients for an out of energy agreed on their own then later also the major cause for information as well. That's been known for now sometime and so strategies to address a yes whether it's cove nineteen induced or otherwise need to take into account the fact that then later contributes to that inflammatory burden patients with they as an academic. You've done functional

Respiratory Distress Aqua Lung Therapeutics Acute Akwa Lung Therapeutics Joe Garcia Biotech Company United States Curiel Covid Founder And Ceo Researcher Oregon Bacterial Pneumonia China Lewis Kobe
How scientists are thinking about reopening labs

Science Magazine Podcast

04:59 min | 1 year ago

How scientists are thinking about reopening labs

"We now speak with David Grimm online news editor at science. His recent article navigates the treacherous waters of researchers returning to their labs and fieldwork amid the coronavirus pandemic even for scientists fortunate enough to resume their research. Strange situations await greatly reduced lab teams physical distancing and face masks and the risk of corona virus infection to name a few. Hi David Angel. There's been plenty of talk about how and when researchers might return to their labs and it seems that now. The time has come for some of them. Could you highlight a few major studies that have now resumed work in a sense if it remains true that most labs especially labs that are not working on component virus are still closed or only partially open right now? It seems like labs in Europe have opened a little bit earlier. There was allowed to open a couple weeks ago and more opening now when my story I talked about any everything from research vessels going out in the Gulf of Alaska to study fish populations to archaeologist steady each feces and so obviously none of us have to do with corona virus which is why all these studies were shut down but some these are gingerly starting to reopen a little bit. How our institutions deciding which labs reopen? Will you know? It's really interesting. Some places are allowing all labs to reopen but the after we open a very limited capacity Aquino only a twenty five percent capacity will be a couple of people can be in the lab at one time in other places. Universities are prioritizing critical projects. And in that case that that be you know. Post are for Grad. Student is only a couple months away from finishing their post doc or their thesis and they just needed to accomplish more experiments. They're being allowed to come in just to finish those experiments and some of them. Don't even have supervision right. Now is not the case. So one re-stripe talks to a Nora Sistiaga who is at the University of Copenhagen Denmark. She's wants studying each and feces and she was allowed to go back into her lab by the team because she was so close to finishing data that she needed to complete her post doc but she can't do that because the restrictions are such that she can't go in by herself and her project requires somebody to supervisor and so the both can't be there at the same time because the restrictions imposed by the university so even though the genes allowing her to go back. She can't go back because she she. She can't do this work by herself. Even cases where people are allowed to go back. They're not always able to go back. One thing. Everyone even those outside of science or grappling with is that business as usual is no longer a thing what changes are being implemented in labs and feel work that might represent the new normal. Yes so the biggest thing is is the physical distance thing. So that's why the numbers have been so reduced so you imagine if the lab of twenty people were crowded together on the small lab benches knees take orders. That just can't happen right now. Because of the risk of transmitting corona virus and so she having instead his labs being allowed to have. Maybe two or three people come in Saint Time. And everybody's got to be in a separate room or the least have to be six feet of ARD and so that's one of the big things and also most decisions are requiring employees to wear face masks so even if you only have a public lab. Everybody's gotTa wear face masks at all time. Those seem to be the standard things. That are the same regardless of the type of laboratory. You're talking about. There are differences now because some labs are used to labs at deal with ancient DNA for example. These people are wearing full protective gear all the time because they don't WanNa candidate per sample. So they they are. They're already very used to wearing masks. Whereas maybe physicists owners who don't normally have to wear masks are now being forced to wear those fulltime. At least when they're in laboratory conditions a lot of these scientists and institutions are taking that leap to reopen labs and go back to research are scientists and institutions preparing for the possibility of labs having to close again. Yeah that's the really big problem. Because even as lobs kind of gingerly reopen and they're taking all these protective measures to make sure researchers can be there do their experiments. There's always a chance that things will up again. There could be an outbreak of cases in a particular area and then Milan has closed down again with university has to close down again. That's still something that's being actively sort of considered about how to deal with that and again different universities institutions dealing met with that in different ways so for example the Swiss veteran institute of Aquatic Science narrow allowing people to come back to work but one of the edicts is. Don't start new projects and don't start any projects that can't be stopped on short notice and the idea is that you don't want to start a project that's going to take you a year to finish and has to be done continuously. If there's a chance your research going to be shut down again in a month or two and so it really trying to ties the work. That is just finishing up or work that can be done. Maybe just a few weeks in case things have to shut down again.

David Angel David Grimm Gulf Of Alaska Europe Saint Time News Editor Institute Of Aquatic Science Aquino Nora Sistiaga Supervisor Milan University Of Copenhagen Denma
"ard w" Discussed on Cell Culture Dish Podcast

Cell Culture Dish Podcast

09:10 min | 1 year ago

"ard w" Discussed on Cell Culture Dish Podcast

"Which showed that we. We might be able to dramatically improve outcomes in situations where there was pulmonary inflammation and other things going on that current medical approaches. Really don't provide an effective solution for just getting back to the the ventilator you actually correctly stated one of the consequences of having patients on a ventilator for an extended period of time I realized how risky and problematic that is because the longer the patient is on the ventilator you're creating stress on the lung tissue over and over and over again every time you force oxygen into the lungs and it can lead to fibrosis or scarring and other types of problems which frankly can make the path very difficult for patients. Even when they're off the ventilator to ever recover from that but from preclinical perspective to get back to your question about why we chose. Arts. It started with the the animal studies that we did but then something very interesting happened. Just a few years ago. We were doing work with several of the leading transplant centers here in the United States that we have a good relationship with and some of the investigators came to us with a problem that they that they're hampered by in so these transplant specialists were focused on a challenge that they have in the field of lung transplantation and specifically what they told us was they said. Hey we've seen the work that you guys have done in other models of acute lung inflammation and we WanNa talk to you about a specific area challenge that we have turns out that about seventy five percent of belongs that are isolated. From organ donors that are then designated to be used for transplantation procedures. Seventy five percent of those longs become highly inflamed and they start to go bad essentially before the transplant procedure can be conducted and the reason why the lungs go bad is wants. Their what's their harvested. If you will from the donor and either put on ice or stored for the subsequent transportation procedure the Pulmonary Tissue begins to experience inflammation from the resin immune cells and other things in the lungs caused belongs to become compromised over time in very frequently within. Just a few hours. The belongs become again highly inflamed filled with fluid. And you couldn't transplant those lungs into patient. That needs along transplant. Because essentially it would be like giving them arts. You would be taking out. You know the normal longs or not the normal. Because they're obviously highly compromised and patients need a transplant. But you would essentially do a swap in in transplant. The new from the donor. But if you transplant in those new on in their highly inflamed and they don't function properly than the patient's going to be in a in a bad way right from the get go so they came to us and they said Hey we want to explore with you guys. We want to see if we take some of these logs. That have already started to go back. They bar there already compromised experiencing severe inflammation and they're compromised in terms of their ability to absorb oxygen. We want to refuse one side with multi. Stan and as a control will refuse the other side with the scene. Lean that we use to administer the multi stamina. Let's see what happens. The logic was that since we saw in the animal models of big impact on restoring pulmonary function and reducing the inflammatory mediated cascade pathways that we might be able to turn things around sure when we did that study we saw in actual human lungs that were isolated from donors that there was a dramatic impact that when we per fused one side of the lungs with multi stem. It actually caused the pulmonary function to return back to the normal range. Dramatically reduce the inflammatory mediated damage. And and so these transplant specialist immediately. Suggested hey maybe we should just start taking human lungs from donors than star per fusing them with multi stem as a way to to prep these long so that we can keep them in a better state for a longer period of time or have a higher probability of being able to conduct the transplant procedures for patients that need along transplant ultimately though that's a limited number of patients that are impacted that in in the United States is probably somewhere around fifteen hundred two thousand patients per year. And when we looked at that we thought you know that might be a very very difficult. Clinical trial to enroll and so we started to think about alternatives. And we realized you know what arts which is estimated to affect a couple hundred thousand people per year here in the United States that might be a better target because the exact same process by it might be that. There's a lot more patients out there that we could enroll for a study like that. Same underlying biological principles but it just might be simpler study to actually run at the end of the day so we decided to focus on that ultimately we ran a clinical trial at leading pulmonary critical care centers in the United States and in the UK and it was about a dozen centers at all so we ran study. We just recently announced the one year. Follow up from that study until the primary results which were presented last year. The American Thoracic Society meeting showed that we had a pretty dramatic impact in terms of reducing mortality within the initial roughly one month assessment period. Which is kind of the primary evaluation period In terms of improving mortality improving ventilator. Free Days and I see you free days for patients that had been diagnosed with ours and were really really sick and the biggest impact was actually observed among the patients that had severe art so they had the most compromised lung function. And we saw that. That's where we were. We were actually moving the needle the most if you will just more recently just a few days ago we announce the one year highlights from the follow up and what that showed was that not only we helping patients in the short term in terms of improving their clinical metrics in their odds of survival but we also showed that we were dramatically. Improving quality of life outcomes for many of these patients particularly among the most severely. Ill that's pretty know where because a lot of the patients that have ours you can imagine. Imagine you're kind of trapped in your own by and you're in the hospital in the ICU. You're on ventilator. You can't move around you've got a team of nurses or other people that are taking care of your most basic needs and you might be like that for weeks. Many of these patients have to be put into a medically in comma. But you can imagine that when patients actually ultimately from that even when they're discharged there's a big overhang from that there's a physical overhang there's a psychological overhang in many patients. Never really get back to the quality of life that they once enjoyed or that. Ideally they would like to get back to One of the really exciting things are study. Was We showed? We were actually helping. Many patients get back to the quality of life and the independence level that they really wanted to get back to and I think when you couple that with the clinical observations from the study. It was pretty exciting. We've seen similar types of responses in some of the other things that we're focused not clinically so for example we conducted a phase two clinical trial in treating schemic stroke patients which is another huge area of unmet medical. Need lot of people don't really realize that for patients that suffer and a schemic stroke. There is a very tight time window for for patients to get to the hospital and then undergo treatment with the limited treatment options that are currently available and are face to study showed that we could effectively help patients up to thirty six hours after they had suffered in schemic stroke and for both arts and for stroke we've received fast track designation from the FDA and some other exciting designations are stroke program for example. Got Something called harm at which is like the equivalent breakthrough therapy designation from the FBI. And now we're well into phase three study that we're running for stroke patients and a lot of people believe that for both arts and for stroke we might really be able to meekly improve clinical care for patients that in many instances have nowhere else to turn. And frankly that's exactly why we founded the company going back. Twenty five years ago was because that was the type of impact that we were really committed to having. Well that all sounds wonderful and fascinated by the arts therapy and think it's just a wonderful development in a situation where people have very few options This this is just fantastic. I think I can speak for listeners when I say that will all be following your progress. Sue The clinic end to commercialization very closely and are very thankful that you took the time to talk to us today. Love hearing about a rejection medicine and selling gene therapies as we have been covering them for a long time. It's so exciting to see these therapeutic. Modalities move from the clinic into commercialization to see new opportunities. Arise so I just WanNa thank you again for your time. State was really very interesting and I really appreciate it. Randi thank you very much. I appreciate your interest in the company and what we're doing and And thanks for spending your time in your report on trying to educate people more broadly about some of the exciting things that are going on in the field. Definitely an in the show notes will include links so that people can learn more about the work that you're doing as well..

United States inflammation Pulmonary Tissue American Thoracic Society FBI Stan Randi FDA UK
"ard w" Discussed on Cell Culture Dish Podcast

Cell Culture Dish Podcast

10:45 min | 1 year ago

"ard w" Discussed on Cell Culture Dish Podcast

"Or just doesn't provide the type of relief that we would ultimately like to offer up the patients that have severe conditions or might be pretty desperate and so that's what the company was founded on in the early days. We focused on some very intriguing non viral gene therapy technology. Something called synthetic human chromosome artificial human chromosomes technology that led to the development of some proprietary genomics technologies that led to partnerships with a number of major Pharma companies and other groups that we work with over the years and ultimately led to our interest in the emerging field of regenerative medicine and cell therapy and for more than fifteen years. Now that's really been the predominant focus of the company in terms of concentrating on. How're proprietary technology may have relevance as an off the shelf therapy in the realm of of regenerative medicine to treat areas in the critical care spectrum for medicine? So these are indications patients. Something really bad has happened to them. They have a very serious condition and they're typically in the hospital and in most often in the intensive care unit and current standard of care is pretty limited and so that over time our focus is kind of grown and involved in recognition of what this technology that we work with might be able to offer up for patients like that and now were in late stage clinical development and have a whole pipeline of various programs. That we're focused on. That's really exciting. Could you tell us about the development of multi stem? And what are some of the unique advantages of these cells? In particular stem is based on a discovery. That goes back. A few years ago to unique class of cells could be isolated out of healthy consenting donors and typically one of the easiest ways to do this is to take a bone marrow aspiration from healthy consenting donor. That's given their permission. And then what we do is we isolate a heterogeneous mixture of cells isolate the specific cells that comprise multi snap Specific cells that we work with her or reverse. He was multi potent adult progenitor cells and became interested in the self going back a few years ago because they had an interesting biological capabilities in characteristics that we thought might lend them to development into therapy platform specifically what we saw about these cells. What's that very unusual growth properties? So most people are aware. Just use an example to kind of illustrate why that's important most people and most of your listeners. Recognize or know something. About the history of bone marrow transplantation or stem cell transplantation. This goes back to the late. Nineteen fifties and early nineteen sixties and of course bone marrow transplantation or stem cell transplantation is. It's also referred to now for every patient that you wanna treat that might be. You need to be treated for leukemia or something. Bloodborne were mad logic malignancy. They're undergoing radiation therapy that wipes out their blood immune forming system and so in order to help the patient survived that treatment which whites out the cancer but it also puts the patient in a highly compromised state. You have to do a bowel nor transplantation or stem cell transplant and those cells are isolated from donors that are very carefully tissue matched with the patient. You're trying to treat now. There's a couple of problems or challenges that relates to that process. The first problem is is that you need to find a donor. That is a very close match. In order to limit the risk of were reduced the incident above Rejection or some of the really challenging complications that are associated with that procedure so things like rappers versus host disease or other things that can happen but the the fundamental problem is that for every donor that you isolate those cells from. You're only going to get enough material to treat one patient and so every time you wanNA treat a new patient you gotta go out and find another donor so that entire process is kind of the opposite of scalable a pupil. It's always one to one. And in many instances you have to search through many perspective donors to find the right donor. That will give you the cells that have a close enough match to warrant under undertaking. Their procedure well. Multi stem is kind of at the opposite end of the scale ability spectrum and that is because the cells that we work with you. In contrast to most other cell types that can be isolated from the human body. Once we've isolating these cells. We can actually grow them up enormous quantity so they have really robust growth properties. And we've published on this and other groups have published on it as well that show the FBI. Cells can be expanded to phenomenal degree. And what we mean by that is that we demonstrated that once we isolate cells from a healthy consenting donor that we can actually produce the equivalent of millions of clinical doses starting with a modest amount of material. We do that. By creating a Master Cell Bank and characterizing that bank and then we can create working cell bank and then ultimately do clinical production runs that ultimately it harnesses the robust growth properties of these cells which are very distinctive and unlike other cell types can be isolated from human by the other thing. That is very important is that we also determined verified validated early. On was that the cells have very unique immunological properties and in fact we've shown through multiple clinical programs in three years of preclinical work that we conducted with numerous outside independent. Labs that we work with that. We can administer these cells just like typo blood. We don't have to tissue match and we don't have to immunise oppress the patients that were administering multi stem to so when you combine that unique skill ability profile with that off the shelf utility. You will where we can administer the cells without having to the tissue-matching without having immunise suppress the patients is really really powerful. And in fact we've shown because of the unique biological properties of these cells then the ways that they can both ways in which they can help influence healing in repair and reduce inflammatory mediated damage or do other things that they have relevance across a range of pretty interesting and exciting therapeutic indications that we've worked on so in summary it's really those combination of factors the scale ability the lack of a need to tissue match or immunosuppressive. The off the shelf utility of it. The other thing is is that we. We've got stability data that shows that we can keep these cells stable in frozen form for years if necessary and so when you combine all of those factors it creates a very powerful package that we think could create a lot of opportunity for us and the people that we work with in terms of using it as a way to treat patients that have suffered from a range of different events whether it be a stroke or or acute respiratory distress syndrome or some of the other indications that were focused on. That's really interesting. I think for a long time been looking for a way to make south therapy more scalable in it. Sounds like a really great solution to that issue. In a lot of ways you mentioned acute respiratory distress syndrome. Or could you tell us a little bit more about it? And how a multi stem can help patients so ours is a condition where the the lung tissue has become highly inflamed and Noah functions the way that the patient needed to so basically what ends up happening is when the pulmonary tissue or tissue becomes inflamed and it starts to fill up with fluid a process referred to as Dima the long can't really absorb oxygen in the way that we that we need to and when the ability of belongs to absorb oxygen properly has fallen below a critical threshold then. The clinician really has no other choice but to put the patient on a ventilator so they're literally forcing oxygen into the longs of the patient and that's because it doesn't matter how many breast patient takes when their lungs are inflamed and in filled with fluid. They're just not going to get enough oxygen to be able to survive that and so clinically. What has been done for quite some time as you put the patient on a ventilator force oxygen in the lungs the high concentration in an effort to keep the patient alive get enough oxygen into their bodies so that they can with organ failure or have other things happen to them that really could end up being lethal or Just create a whole bunch of complications or other adverse events that are very challenging and problem that we discovered a few years ago. That multi stem has relevance in this. Because we were looking at various models that suggested that if we minister multi intravenously that the cells would actually home to the lungs when there's active inflammation in the lung tissue and have some pretty dramatic effects in terms of helping the body recover from those types of events and just recently we actually now some pretty sunny clinical data from a exploratory study that we have been conducting that provided a lot of evidence to show that we could really help patients that are diagnosed with arts. It's a pretty big problem or being a condition that affects a few hundred thousand people in if you look at North America and Europe which are two primary geographic areas that we are most focused on and we have a partnership in Japan with a company Hugh. Leo's that's also focused on developing our platform over there for arts patience and collectively. We think there's a lot of reasons to be hopeful and optimistic about how we might be able to really improve the standard of care for these patients. The really isn't a drug. You can give them now. That can really help them survive us. It's put him on a ventilator. Kinda hope for the best and then hopefully you can try and win them. Walk into later once they turned it. Wow that is so exciting and vaguely familiar with the ventilator situation but I. I'm aware that there's a lot of other issues that can happen. As a result of being on a ventilator itself and so Having away to address an issue that really isn't being a very effectively right now is a really exciting development and really encouraging. I think for for the medical field. I'm curious why did you choose to pursue arts and then also would love to hear about other indications for multi stemmed that are being looked at so we are very much part of? I think one of the things that were very proud of that as an organization is they were were really an evidence based research and Development Organization and the short answer for why we chose ours was because the evidence began to mount over a period of years in a series of studies. We conducted the told us that we can have an impact there and it started with miles that we were working in a few years ago. We were looking at those small but eventually large animal models that resulted in acute lung injury. They could be precipitator caused by a variety of different things and what we consistently saw. These studies was when we administered multi stem we could overcome the inflammatory mediated damage and some of the other things were happening in the lungs..

respiratory distress Master Cell Bank leukemia FBI immunise Development Organization Japan Noah Leo North America Dima Europe
"ard w" Discussed on Newsradio 700 WLW

Newsradio 700 WLW

04:17 min | 1 year ago

"ard w" Discussed on Newsradio 700 WLW

"We will get more the industry headlines coming up several others to touch and let me see here someone sent me an email yeah they did the previous caller what what was the name of the doctor the previous caller Steve the chemist was talking about it is Dr Cameron hi all K. Y. L. E. side L. S. I. D. E. L. L. bring Kyle's Adele I pulled up one of the stories so he was talking about believe this is the one he was mentioning the Brooklyn Dr warning that the critically ill cove it patients are being inadvertently harmed by the very same breeding machine being used to try to get a live Dr Cameron Kyle side tell the emergency medicine physician said we're putting breathing tubes in people and putting them on ventilators the dialing up the pressure to open up their lungs I've talked to doctors all over the country and it's becoming increasingly clear that the pressure we're providing maybe actually harming their lungs that is highly likely that high pressures were using are damaging the lungs of the patients were putting the tubes in a two minute video posted on we only get the said Wednesday that was is from last week urged to today here it's dated April the six the so okay let's see the board certified emergency medicine Dr sigh del I said we ran into an impasse where I could not morally in the patient doctor relationship I I could not continue the current protocols which again are the protocols of the top hospitals all over the country so now I'm back in the E. R. were it setting up slightly different ventilation strategies indeed he said to describe the situation involving the ventilator settings is not our fault we did not know this is how we treat a cute respiratory distress syndrome ards this is how we treated it for the last twenty years he insisted we need to change these protocols in cautioned that the time for us to change them is rapidly diminishing Kovin patients need oxygen they do not need pressure they will need ventilators but they must be programmed differently he says in a second video he posted he said that this cove in nineteen is a disease that does not make sense to us a disease for which our usual treatment doesn't work the summer question whether this is a long disease causing blood problems or a blood disease causing lung problems I don't know what it is but I know I've never seen it before people are dying of a disease we don't understand thousands of people old and young and yes there are young people dying now he's also said that code nineteen lung disease as far as I can see is not a pneumonia but seems to be some kind of a viral induced disease that most resembles high altitude sickness it's it's of tens of thousands of my fellow new Yorkers are on a plane at thirty thousand feet in the cabin pressure is being led out these patients are slowly being starved of oxygen and while they look like patients absolutely on the brink of death they do not look like patients died of pneumonia well let's see James hi a physician assistant who was new Jersey's first conveyed patient told the post that.

"ard w" Discussed on KLBJ 590AM

KLBJ 590AM

01:50 min | 1 year ago

"ard w" Discussed on KLBJ 590AM

"The near flawless event was the issuance of a new traffic ticket to alien mourners for hovering their craft to close to a fire hydrant ards widow is considered arts beautiful widow Ramona concluded the ceremony by unveiling a large memorial stone shaped like an ancient A. M. radio the stone memorial was engraved with a fitting epitaph the man that kept us up at night through so many many many years dear lord dear lord art was all talk but his talk was art and that's it and then at the bottom there's a little Asterix that says you never know you never know it could happen yes we'll be right back the premier networks was art bell hosting coast to coast AM on this somewhere in time your full delivery.

Greninja Voted Most Popular Pokemon by Players

Pop Culture Cosmos

01:46 min | 1 year ago

Greninja Voted Most Popular Pokemon by Players

"Pokemon community had a vote on the most popular POKEMON. And I gotTa tell you. I was Kinda surprised. That Gra Ninja is the most popular POKEMON. Right now out there in the Pokemon community your thoughts on Gr- Ninja getting the top spot and other pokemon Cario Mimic. You Charles ARD umbrella there. The top five but Pika chewed the most recognizable of the mall is barely even the top twenty and Evey is just barely twenty there so I asked him a friend. What's going on with people's changes in taste in what they love about. Pok Mon I duNNo. I feel like the older generation of Pokemon fans have kind of fallen off the wagon such as you and I and a newer generation of pokemon fans is there and the ones that are from older games. That are recognizable are only because they still take up so much spotlight in the newer games. Too like for example the POKEMON. Let's go e V pokemon. Let's go peek. At you like you could fly your charter around right like you still got those Pokemon and they were still fun to play with and you needed to use them to get to certain parts of the map like they still take up centerfold in the newer pokemon games and I think that's what keeps them alive especially like Ginga gingas. Always in the cartoons. He's in the movies. He's got a bunch of plush toys of gang are everywhere you go? And it's it's they've done a good job of marketing. They market the POKEMON that they want to be front and center right the and you know they. They have a certain set. So we're not gonNA see like a d glit- or something you know making that top list were just gonNa see the ones that pokemon decides to focus on in the new

Evey Ginga Gingas Charles Ard Pika
Asking yourself personal questions

The Inner Dialogue

09:54 min | 1 year ago

Asking yourself personal questions

"Hello everyone was another episode of the Inner Dialogue Young today. I want to talk about something that is essentially a follow up from last episode which was about or creating a boatswain space via south. If you haven't hosted I will link it in the show so you can hear it. It's a pretty small episode so go ahead give it. Listen is what you say and come back to this so now that you have figured out how to to create a personal space for yourself. It's time to actually allow yourself to be you and speaking speaking from experience. If you haven't done that for years this can get super hot and it can get scary scary to go deep into a sewing thread of thoughts and figure out who you really are what you believe in and how do show that I do. The work and some cases decided not to show that the world because the world isn't ready for it yet and that if that happens I'm I'm saying right now. That suicide and I am in such a position right now but I do hope that eventually either I get enough. Courage despoiled becomes easier. Do Live my chosen. But anyway I digress. I want to talk about how do just allow yourself ally yourself to be who you are inside your mind and you might be wondering why I am even talking about this when we are who via inside abrines as we don't have anyone else that do prodan in front of you know. I don't think that's true. I think Detroit. We grew up with the beliefs. We grew upward. Defoe sauce to shut Abbad if our brain side hi default that we are not capable of dealing with without actually breaking down that old belief system that we've created and that is hard. I grew up believing or now the hoping that I would be one of those kids kids who didn't have to fight society who fits society's needs and wants and expectations perfectly and while growing up for majority the F.. I guess my childhood I felt like I was the Because when I was growing up my parents had issues. Like were disappointed pointed with my sister because she wanted to be boo. She kept on getting into relationships and they had to put her out of it. And then she you wanted to dress inside unreas- unreas- died. They were not safe for her to do in the culture. The please where we grew up in so a lot of my childhood was my parents during my sister not to do things I naturally didn't WanNa do. Sofa meows like yeah. I'm lucky I fit into the world. I am she could. My parents are not GonNa get disappointed in me because I hate rain dresses. I heat weighing all the things that my sister got school it for wearing or I don't like dating people so I'm good. I don't have to worry about my parents being disappointed in me and then it was this. I don't know this warned of the desire to be the perfect kid that stop me from allowing myself to you get to know who I really am for the longest time and I make it sound like. It's my burns Ford. The have been the most supportive in my a journey of figuring myself out the have been telling me for years that it doesn't matter who I am who I am amazing. Yeah for some domes and some woods that I've used to describe myself. They might have to take a few to accept it But at a basic level with using words that come with its own stigma and stuff my bands understand to some level that I am not like. I don't know the Hetero normative society that to grow grew up in some lucky that way but the first I I am that I can allow myself to think. I'm not straight to a lot of these. You've working in a lot of society starting to on me that I don't fit in because I remember I saw a growing up. I mean I guess our screw up our and growing up but I remember during a donut shops and during my internships what used to happen Rusada. As she was not only don ships it was also just university seeing people being more open about their relationships and their life the life plans and during my internship my first doing doing chefs. Actually one thing I noticed was that everyone wanted relationships. It wasn't just my sister. Everyone needed mutation ships relationships actually made people happy but the funny part was. I thought that I wanted them do. But every time I imagine myself breath in a relationship or a close to actually getting into one I would freak out because nothing felt natural to to me Even the act of going on a date with someone awkward and honestly not really something that came naturally to me so Assad finally feeding that I don't fit into the world but then it didn't really already hit home that I could disappointment burns by nod being in relationships which just remind you was something that made my bands happy when I was younger but my sister was getting married and I suddenly realized how my Benz. I didn't want me to be in relationships at that point in my life but if I didn't grow up and get married and had a normal sorry for Houston Garwood. Had A SIS had relationship. I would be a disappointment. But every damn auditing my sister was doing and that they were generally speaking her happy I freaked out because I did not one that for myself and in this freaking ARD idolize that it had been this todd that kept trying to come up in my mind for the boss for years that had allowed to come up because the fact that I'm a section men that I'm not street was too much for me to handle because being strayed is the only thing that my parents taught was okay and this was my end two years ago at this point. I think they've come far far. We from there now probably understand that better. Uh honestly I haven't had the conversation with them but I can sense it against them learning more and understanding more but yeah so when I saw assisted miles like okay. It's time to ask myself if I actually Street if I actually went to go warhead and do the same marriage SIS head world that she's in and even though I knew the answer I actually had to say dot plot to myself I had to don myself said you have to see dod lied to make a true and I remember just lying on Meru Monday and going like no. I'm not straight I'm sexual and for many people that might feel like it's not a big deal dubious actually and accept yourself because society's nod GonNa not GonNa Sean you like the way they treat people who annoyed Roy who are some other sexually not trade and honestly I agree but also you have to realize as someone who is a sexual and eater mandic antic growing up in a world that expect you to be sexual in some sense to be romantic in. Some sense is odd because most so my childhood felt like everyone else was being fake. Evan else was not being real but no one allowed me. Gave me the words to understand that I'm just just different. No one and on me told me that it's okay. Do this but the other people around me a naught featuring this because I generally thought everyone was just speaking things but yeah back to having those difficult conversations with yourself. I think for me the biggest thing that help who is breaking down into smaller chunks for example when Assad thinking about did my gender so I started questioning gender pretty much a year after aside. I accepted that I was not straight and started questioning because I met Trans Man and his experiences and my experience growing up were outsource

Assad Defoe Abrines Detroit Evan ROY Houston Garwood Rusada Todd DON DOD
Trends in Natural Language Processing with Nasrin Mostafazadeh

This Week in Machine Learning & AI

07:58 min | 2 years ago

Trends in Natural Language Processing with Nasrin Mostafazadeh

"All right. Everyone welcome back to our AI rewind 2019 series in this episode will be covering covering NLP. And I've got the pleasure of being on the line with Nassreen Mostafa Day. She is a senior research scientist. At elemental cognition Nassreen. Woken back to the PODCAST. Sam Glad to back. Thanks for having me definitely glad I to be speaking with you again. We last spoke back in August of twenty eighteen when we spoke about contextual modeling language envision and some of your research This time will be reviewing some of your thoughts on the most important papers and developments more broadly the and the field that you work in natural language processing in twenty nineteen. I'll have folks refer back to that previous episode for a a little bit more about you and your background and what you're working on but to get this conversation started. Why don't we just start with your kind of broad? Take on twenty nine thousand nine in and Lt what was the was a big year for an ob sure so. Actually I think yeah thing into the nineteen was actually exciting. You're out the you know. These large pre-trading Models have been stretched widely to various various different directions and you know slowly but surely is community. They've started the sink about elected problems. They have the weaknesses the blindness spice up up Citing the sort of paradigm shifts that you're seeing in an LP sort of are into twenty twenty now kinda started. I'm I can reflect back on the decade Started back in two thousand fifteen to sixteen or so in various Task could start to get tackled by relatively straightforward approach that you would just including input tax. It could be looked looked at as a sequence of wars characters etc.. The new US like attention to actually Basically looked back back into the included representation video trying to predict something for task. which could be a sequence of Tokens as evacuate does container so so You know Chris Manning which is one of the pioneers of our field. The had this Basically the Belief from him that he believed him BIOS hegemony which he believes that basically no matter what the task is out there not task if you try wireless wirelessly omitted and use attention to attend back to the Basically important including a of the input you basically can Actually the state of the art knows this referring to the tension is all you need paper so attention is it only you need. Paper is more resent so that was then. The transfer miss came to picture. This has been hellish how fast field is moving through two thousand teams still as I said like the consensus in all it was that you can reach you. Choose state of the art if you just throw it. Violence attached that was the recipe and back in that tire member. Like when I was like talks I would conclude that look although that has been true or a host of different benchmarks a happens that for detested require vast amounts of background Dan knowledge reasoning in basically Require salish along tastes Not yet achieve state of the art or near human performance servants using these by Malls so fast forward just one year. In two thousand eighteen we had like L. modes steep contextualized were presentation The basically started sort of this one more step forward of billing these large language models which happened to be contextualized so preaching on a very large corpus and then fine tune of data stream which should sell started meeting lots and lots of different as state of the arts and establishing brand new state of arts and so the test that I had in mind when I was personally criticizing the fact that Oh look by throwing Added attention on a particular benchmark jump. Necessarily she stayed at the ARD causes reasoning tasks which is something that I personally absolutely very passionate about. It happens to be mined line of research and so the particular task was a storage tasks which I talk again. The lastingly testing we talk. Radio is specifically story Koehler says which is tested given a sequence of four sentences on which form a coherent story very very short story. The task is riches between two alternative endings to that story which Yunos designed basically to evaluate systems commonsense reasoning reasoning capabilities What happened in two thousand seventeen? Is that mid two thousand seventeen or so. The attention is unique. Paper came out the transformer paper that you just mentioned a minute or two ago so that paper basically enable aiding effect of other blurry large large pre-trade transformer models that could actually establish the state of the art in various commonsense reasoning tasks one being the. Gt one paper says uh-huh on paper came out around in two thousand eighteen hours which was Utah Training Model. This was a very large language model. Oh that opening. I folks have basically trained on a very large diverse corpus and then fine tune on a small data sets and actually this data said that they highlighted as to the place for me. The most amazing basically progress happened to be story closed as the benchmark. I I really cared about. So they have Notably they have often like around eighty six or so percent accuracy which was exceedingly getting better than the previous Number is that people had reported on the test set and so that really sort of changed my personal mind out adverb. You're going to this. I started believing in the fact that all look although these models may seem to be sort of doing pattern recognition at the scale pitch may not Doing reasoning in connecting the dots in all these sorts of things that we care about in a label as his reasoning. Efi You know do them in the right way or give these models off chance of being trained for on the right Dina says finding them right these center eric capable of doing knowledge transfer. I think that sort of set the ground up for us to move into has nineteen Very had more more of these very large preaching models that then you could basically find on various demonstrating test and establish state of yard. No matter the but they're not they're from our very at coronel t tasks like Shining tests such as historic Costas itself Congress this is reasoning etc.. So I think this has been the main exciting thing about Nineteen where we could see. This wasn't just a glimpse of Wasn't just a one time thing that these models could perform val it continued into two thousand eighteen. And I think I'm actually excited about A scene Improving these people off more about the downsides of these models but yeah I'm very excited to see her. VR going with this paradigm shift into any twenty.

Nassreen Mostafa Day Senior Research Scientist United States LT SAM Dina Congress Chris Manning Utah Yunos DAN Koehler Eric
Modern Time Slips

True Mysteries of the Pacific Northwest

06:27 min | 2 years ago

Modern Time Slips

"Today. Something a little bit different on this podcast. Generally science is acknowledged as something. Let's say a discovery of something and it can be replicated and therefore it is based in scientific fact and the pseudoscience is usually explained away as a simple single phenomena that can't be captured reproduced. So I have on this. PODCAST is a series of modern day. A or modern time time slips began with a white Ford pickup that pulled up to a cattle pasture near Pona City City Oklahoma. This was early in the fall of Nineteen seventy-one if stopped at the gate. Carl Marc and Gordon worked for cattle feed distributor. Were sent to this remote area to pick up a theater but they found their has kept them silent for forty one years. Carl says we opened the gate. which had barb orb wire with no locks and we entered? We went onto the property which was covered with grass up to in some cases over the truck. They drove through grass. Ask to the tank that sat close to Red Barn and got Outta the truck. We realize the tank was almost half full and too heavy to load. Carl said we. We decided to leave and drove around a Red Barn and there. We saw a large two story White House with no lights in front of us. The trio drove back to the cattle feed company and told the boss. He said he'd drained the tank and they could pick it up tomorrow. Carl says we went back to the location to retrieve the a tank the next night he said this time we decided to go through the old white big house on the hill and we brought our flashlights and shotguns. Just in case they they drove onto the property over the past. They've made through the day before they loaded the tank then they pulled around the bar toward the house what they saw burned into their memories. It was no longer there. Carl said we walked up the hill where it stood and there were no signs of demolition no foundation. There's nothing at all what we all seem to witness the night before was no longer there. We've talked to each other over the years but none of us can explain mine division. Did these men witness a time slip. Time slips have been reported throughout history and English women. Vacationing in France Franson one thousand. Nine hundred one claimed they stepped into the French Revolution. The two couples traveling in Spain in the Nineteen Seventies stated an oddly archaic. The hotel. There was simply gone on their return journey. Physicists like Albert Einstein Michio Kaku and Stephen Hawkins have have all said time. Travel is theoretically possible. Our science just can't achieve it but what if nature can another example the light in the sky shown shown white far from the Greens and the reds at Jigsaw during the Aurora Borealis of two thousand four visible in North America as far as the Lower Midwest West Jake fifteen stood outside his parents home in the lake of the ozarks Missouri around ten PM. Twenty eighth of May leaning against a truck rock looking at the lights. He didn't know his life was about to change a bright white glow suddenly filled the northern horizon this look nothing like the the northern lights the Aurora Borealis nor did it behave like that the lights move like the light of a copy machine. The single bar brightness move from west to east over Jake's head and disappeared. I thought that I should maybe go inside at this time and found myself. Unable to move he said Novenas grew in his arms and legs and he blocked out when he woke. He knew he'd been somewhere else. I felt woozy and almost dated. Said time seem muddled in my head. Had He walked into the House to find he'd been outside an hour. It took most of the night for him to tell us parents what happened. Most of the time I kept telling them that I thought the calendar was wrong. It should at least be after two thousand eight he said to this day. My mother remembers bits of this mainly because I looked at her and asked pointblank. Is that black man. Still President. What happened to j seizures psychological phenomenon or did did jake accidentally take a brief four years step forward from two thousand four hundred to two thousand eight Jake slip is just one in a long long line of stories from people who brushed against a different time such as an RAF pilots are victor good ard who encountered airplanes in nineteen eighteen thirty five that didn't exist until nineteen thirty nine one hundred year old Swiss watch found in a Chinese Ming Dynasty Tomb? People may I slipped like this all the time Duncan cal opened the door of his nineteen ninety nine Chevrolet s ten next to a convenience store gas pump trump in Springfield Missouri. Large man accosted him as I left the gas station. Some large melon-headed man dressed in a business suit yelled what year is this. Kel- set the man stood at a spot kill would've walked by when he left the store but he hadn't seen him demand wore dark black suit suit with a rough fiber texture. Kill said along the lines of things in the Teddy Roosevelt era. What year is this? The man yelled again. The the man was white about thirty five or forty years old clean-shaven normal but he asked an odd question. Carol said two thousand three CAL cal. Tolan the man's face contorted anger. What year is it? He screamed at yet cal again. I said two thousand three. The large man screamed the question. One more time I said two thousand three so he could hear me. Cal said then he quit asking. Kelly glanced away from the man as he slid into Swiss truck but safely inside he turned to get another luck and the man was gone. He disappeared from the front of the gas station. Cal said in the Second Institute held to slip into his truck demand simply vanished cal put. The man hadn't stepped inside the store the only place he could have gone in that short amount of the time he was gone.

Carl Marc Duncan Cal Jake Red Barn Missouri CAL Ford Nineteen Seventies White House Pona City City Oklahoma Aurora Borealis Spain Albert Einstein Michio Kaku France Franson Teddy Roosevelt North America Novenas Kelly
"ard w" Discussed on The Dictionary

The Dictionary

11:19 min | 2 years ago

"ard w" Discussed on The Dictionary

"Hello words welcome welcome welcome to this brand new episode of the dictionary there was a brand new one yesterday and there will be a brand new one tomorrow so a number of episodes go for probably five ten episodes ago I mentioned that I was going to talk more about this thing and the next episode every time I do it was to be a guest on the weird Al we're not weird alphabet podcast. I won't go into a lot of detail about this but I did have a great time talking to those guys we ended up recording three episodes originally they said it was only going to be one and then we another one a few days before I left and then we added a third one the morning of and that was great let's see the first one of the three has already aired it is weird Al Song theme from Home Improvement it has an alternative name but it's basically a parody of the friends theme song the TV show friends and it's kind of about home improvement it's more about just being a handyman that really than anything but this was never on one of his albums he's just played it live I think and at the airing of this episode which is Tober Eighteenth they're probably been one more episode from the Weird Alphabet It is the theme from Rocky Thirteen yes rocky thirteen so that was a lot of fun go check out their episodes and I don't remember if I mentioned this but I was actually a guest on another podcast talking about a different piece of piece of what a different band they might be giants I know I've mentioned Emma Lot so this episode is called Fiber Island that was a song that we talked about it's one of the kids songs actually the podcast it's called vis might be a podcast hosted by Greg Simpson so that aired a couple of weeks go from the time of this recording and we recorded a second one which probably won't air for many months but if you like their music goat check that out he's he does really good drop good job talking about every single song with a guest and while I'm at it I'm going to another they might be giants podcast called don't let Pod that is also very good podcast they sort of take a different direction in how they attack the music they kind of go album by album but there's a ton of research that has done is very very well done and it's absolutely worth it I think to get the full picture of who they might be giants are you really do need both podcasts you get a wide range of information all right I've talked enough about that stuff off let's get to the words I wish I had an ad to throw in here lamps get one ark sign a R C S I n e this is a noun from circa eighteen eighty nine the inverse function of the sign as in if why is the sign of zero I think that's zero it's got the low line through it but it's not the normal diagonal line it's a horizontal line and I think that's just how they do it in this dictionary so let's start that over again if why is the sign of zero then zero is the arc sign of why did you learn something now we have arc tangent this is a noun from circa eighteen eighty nine the inverse function of the town engined as in if why is the tangent of zero zero is the Tangent of why I feel like we had a deja-vu now we have have the first form of the Word Arctic A. R. C. T. I see this is an adjective from the fourteenth century one where did it go This is often capitalized of or relating to or suitable for use at the North Pole or the region near it we have three examples as in Arctic Waters Arctic animals and Arctic clothing to a bitter cold synonym is frigid as in Arctic air to be cold in temper or mood as in an Arctic smile you don't want to get an Arctic smile from somebody let's look at the etymology this is from the Middle English Arctic a Art Arctic there's no see a ar tic that is from the Latin arcus which is from the Greek archipelagos with KS that is from Arctic us a Arcadio s which means bear or Ursa major or north and that is akin to the Latin this which means bear and it also mentions the Sanskrit word that I'm not going to try and pronounce but it looks like it's spelled r. Okay S. A. The r the s both look like they have a dot below them so I'm I'm assuming that sounds relatively similar who assists or something but I don't know moving onto the second form of Arctic this is a noun from eighteen sixty seven a rubber issue reaching to the ankle or above I don't think I've ever heard that before or heard of that Form now we have Arctic Char two words this is a noun from circa nineteen o to a whole Arctic Char of Arctic Waters occurring in freshwater or anonymous populations the scientific name is sell sell villainous Alpine's Alpinists now we have arctic circle this is a noun it is often capitalized it also says A. N. C. which could stand for Arctic circle but I don't know where the end comes from so this is from sixteen twenty to the parallel of latitude that is approximately sixty six and a half degrees north of the equator and that circumscribes the northern frigid zone and the opposite of that would be ant Arctic now we have Arctic Fox and there is a picture this is a noun from seventeen seventy to a small migratory whole Arctic Fox especially of Postal Arctic and Alpine Tundra so I don't know where whole Arctic comes from the state basically added an H. O. L. to to the beginning of Arctic oh boy I am stumbling over my words so I may have to look that up and see what that is exactly the scientific name is OPEC's Lago purpose A. L. O. P. E. X. L. Eight G. O. P. U. S. and as mentioned there is a can white drawing of an Arctic Fox which I guess is not that far off from reality because I think the Arctic foxes are white and most of it is white except for some shading all right next we have Arctic Hare sorry there was a loud noise somewhere behind me but I think it was upstate words because I'm in a basement so that sort of threw me off Arctic air is two words this is a noun from eighteen forty two a gregarious hair of the Tundra of green wind and northern Canada that turns white in winter and is a major food source for Arctic predators as wolves and snowy owls sorry hair as you get eaten but that's probably why you mate so quickly because you get eaten up and that sucks let's see the scientific name is Purpose Arctic US L. E. P. U. S. What was I going to say oh why are they gregarious can you tell me do you know why I Arctic Hares are Gregarious Send Me a message oh I was just thinking this morning I may actually start up an instagram account? I didn't really think that there'd be much of a point right to it but I guess technically it might help my exposure I mean come on now that I need help exposing the dictionary every everybody knows about it so yeah I might do that I don't know what I'll post on it but I might do it all right next Arctic tern t e are an this is a noun from eighteen forty four a whole Arctic tern that breeds in Arctic regions and migrates to Southern Africa and South America a couple more a few more all right next we have our tourists capital A. R. C. T. U. R. U. S. this is a noun from does it give me a year it doesn't give me a year this is a giant fixed star of the first magnitude in moods how do you L. anybody probably German might know how to pronounce it this is from the Greek Arktouros which literally means bear watcher there you go I'm guessing the boots word is it day said a Oh why am I blanking on the word the thing in the with the stars I just talked about it like a few episodes go anyway let's move on to arcuate R Q ard or art does not give me quality or being associated with some thing especially conspicuously or excessively we have three examples breath.

Arctic Fox Arctic Hare Arctic Arctic Char Postal Arctic OPEC instagram Tundra Canada South America Alpinists Southern Africa A. N. C. H. O. L. L. E. P. U. A. R. C. T. U. R. U. A. L. O. P. E. G. O. P. U. S. Eight G
Fatal Books

5 Minutes in Church History

04:21 min | 2 years ago

Fatal Books

"Sale and saw this title on a book spine and I knew I had to have it books fatal to their authors sometimes we feel like we're going to be done in by reading a book but these are books that do in their authors and as I'm perusing the table of contents here I see the first category is theology and among the many names of theologians who lost their lives because of a book they wrote there are familiar names William Tindale John hus Savannah Rola these are folks we've talked about before we're on five minutes but they're also some new names William of autumn and able ard let's talk about those two and their fatal books well William of Autumn was born and a little rural village named autumn in Surrey a bit to the South and west of London and he went from one shire to the next Leaving Arkham and going and studying at Oxford well then it was off to Paris and as he got into Paris he began writing against Pope John twenty second and he wrote his book defense of Poverty and now let the author of books fatal to their authors pick up the story from there the defensive poverty startled the whole of Christendom by its vigorous onslaught of the vices of the papacy and the assumptions of pope on the twenty second the latter ordered to bishops to examine the work and the invincible doctor that's what William of autumn was known as aw was cast into prison at Avenue on he would certainly have been slain had he not contrived to effect his escape and take refuge at the Court of the German emperor to whom he address these words to May defend us gladio Ego Tae Defendthem Kalomo defend me with the sword defend you with the pen there. Arkham lived and wrote condemned by the pope disowned by his order the Franciscans threatened daily with says of Heresy Deprivation and imprisonment but for them he cared not and fearlessly pursued his course becoming the acknowledged leader of the reforming tendencies of the age in preparing the material for that blaze of light which astonished the world in the sixteenth century so there we have it William commend is book going after Pope John The twenty second and it eventually being fatal to his being well we also have able are and his book introduction to theology was fatal to him able artists probably more well known for his letters than his book these letters to hello es and they're labeled romance as the Canon of Notre Dame in Paris he was enormously popular but alas he was a heretic he denied the Orthodox view of the trinity the end of the person of Christ a council was convened and condemned his books and him he was imprisoned he was beaten and he was then released well he didn't learn Lesson because he wrote yet another book with yet more Heresy And he squared off with Bernard of Clavo to give you a sense of Bernard of Clavo he is one of the you medieval figures that Martin Luther actually liked and so Bernard of Claro showed up Abe Lard he was arrested again was exiled to a monastery at Clooney in there he lived out his life and when he was buried his remains were placed next to those of his beloved Hellos well it's not only authors that have difficulties with books this book also identifies printers and booksellers and publishers who were done in by books and mentioned specifically to publishers who printed up the BIBLIOTHECA SACRA comb interpretation abyss at Pastilles that is Sacred Bible with interpretations -tations it was a massive work nine hundred pages written in thirteen forty and the pope ordered to printers in sixteenth century to print it and it bankrupted them when all was said and done they were left with eleven hundred ponderous tomes on their shelf and no money well that's it

William Tindale Pope John Paris Bernard John Hus Savannah Rola Arkham Clooney Bernard Of Clavo Pope John The Abe Lard Surrey London Clavo Martin Luther Oxford Claro Pastilles Twenty Second Five Minutes
"ard w" Discussed on Newsradio 1200 WOAI

Newsradio 1200 WOAI

02:23 min | 2 years ago

"ard w" Discussed on Newsradio 1200 WOAI

"While you're on home. I'm pissed off Donald Trump. By moon to Poland. Some data music. About why would you like to be one? How's he doing now? Okay. He pretty rational rational. John good case. Brand. Trump to potent really how they get. Day mad at Trump. Ard cullen. Trump. They mad at Trump. They moved a truck to them. Oh, okay. All right. Okay. I'm glad you get to vote because you're pretty rational. I mean overall pretty rational. Me. Pollen. What we're doing? How do we how do we reason with people go?.

Donald Trump Ard cullen Poland John
"ard w" Discussed on WGN Radio

WGN Radio

01:55 min | 3 years ago

"ard w" Discussed on WGN Radio

"Ard with Wells Fargo three percent down payment on a fixed rate loan. My human realized a new home was within. Reach. Learn more at wellsfargo dot com slash Wells Fargo home mortgage down payments as low three percent on a fixed rate loan require mortgage insurance has to home mortgage consultant about loan requirements. Wells Fargo home mortgage is a division of Wells Fargo Bank NA equal housing lender. NMLS Alrighty three nine hundred one. Using an overpriced trash bag pricey pricey bag that breaks. A smelly bags? Time to switch to hefty ultra-strong trash bags always at an ultra low price. There are best bags yet. And they cost less than glad force flex were sold head to head. So you'll be happy. Ultra strong with Armand hammer odor control available at Sam's Club. R M O B zero one seven two hefty Wimpy radio two thousand nineteen with glad and force flex Sam's Club thirty. Using an overpriced trash bag pricey pricey bag that breaks. Or a smelly bags? Time to switch to hefty ultra strong trash bags always at an ultra low price. There are best bags yet. And they cost less than glad force flex were sold head to head. So you'll be happy Abby hefty ultra strong with Armand hammer odor control available at Sam's Club. Here. Everyone's favourite weatherman. Tom skilling weekday afternoons at four on the Rokon show ended want this seven twenty WGN. Chicago smart speaker user, just say play WGN radio and tune in. The news is sponsored by chocolate wine and spirits, expo dot com. Seventy one here is David Jennings..

Wells Fargo Sam's Club WGN Tom skilling David Jennings Chicago consultant Abby three percent
"ard w" Discussed on 106.1 FM WTKK

106.1 FM WTKK

01:58 min | 3 years ago

"ard w" Discussed on 106.1 FM WTKK

"Station. A suspected terrorist bombing at a cathedral in the Philippines. I'm an Carrick, Fox News. At least twenty people are dead Eighty-one wounded after two bombs explode during mass on the southern Philippine island of Holo the first blast inside during mass sending churchgoers running for the main door. The second explosion about one minute later near the entrance where army troops and police were posted the military is looking into a report that the second device might have been attached to a parked motorcycle. Holo island is known to have Abu Sayyaf militants blacklisted by the United States Philippines, as a terrorist organization because of bombings kidnappings and beheadings five people are dead in Louisiana, please. No the suspect. One year old Dakota -tario Livingston parish sheriff Jason ARD, we've only had one dealings in the past cheerio here Livingston parents, which is a misdemeanor theft on a misdemeanor simple possession of drug paraphernalia. Please. Say the victims are terriers girlfriend summer Ernest. Her father billion brother Tanner and the -tario own. Parents government workers are back on the job this week lawmakers now have a three week deadline to try to work out a border funding dispute central to the thirty five day government shutdown if we don't get a fair deal from congress. The government will either shut down on February fifteenth war President Trump says he'll use executive authority to declare national emergency. Senate Democratic leader Chuck Schumer said Democrats are firmly against the wall. But we agree on many things such as the need for drug inspection technology humanitarian aid, strengthening security at our ports of entry. The deal includes a bipartisan house and Senate committee to negotiate border spending on Capitol Hill, Jared Halpern, Fox News Venezuela, stepping back on demand for US diplomats to leave the country immediately after the US backed the opposition leader as president. This.

Holo island US Philippines Fox News president Carrick Senate Chuck Schumer Trump Senate committee Fox United States Philippines Jared Halpern Jason ARD Abu Sayyaf Tanner Dakota
"ard w" Discussed on 850 WFTL

850 WFTL

02:11 min | 3 years ago

"ard w" Discussed on 850 WFTL

"Weekdays at noon, news talk, eight fifty W, F T, Al West Palm Beach. Sunrise lake worth. From ABC news. I'm Todd and Louisiana. Authorities say twenty one year old Dakota -tario is the prime suspect in the shooting deaths of five people Saturday, including his parents. He's also the suspect and a triple homicide that occurred in the neighbouring parish where terriers girlfriend her father and brother were killed Livingston parish. Sheriff Jason ARD, we do not have a motive is still undetermined after speaking with the mother of. Pook was believed to be his girlfriend who was on. No red flags. There's no no sign of anything. So that we we have no motive at this time Terry, oh is still on the run armed and dangerous. According to a thirties. The government is back open following the longest shutdown in US history. Democrats and Republicans now have three weeks to hammer out a deal agreeable to both parties. President Trump insists he's getting a wall. But the opposition says, no speaker of the house Nancy Pelosi is insisting Democrats won't budge not clear on okay now had been very clear on the wall. Pelosi scoring political victory over Trump who reopened the government without getting any of his five point seven billion dollars for the wall. ABC's Tara Palmeri park. Rangers are back to greeting visitors at some of the national parks that have been closed and flight operations. At major airports are returning to normal lines are being drawn in Venezuela after the US and several other countries publicly backed national assembly president one Guido as the country's leader a military leader in the US posted a video online Saturday. Saying he now backs quite up. He called for the rest of the military to turn against nNcholas Maduro Venezuelan foreign minister Ariza extended the amount of time US diplomatic staff had to leave Venezuela on Saturday. He gave the American embassy thirty more days and promised to create quote interest sections to work on keeping the embassies open. Then as well and President Nicolas Maduro had given American authorities until Saturday to close the embassy and evacuate staff. ABC's Cody Weddell in Venezuela's capital Caracas. This is ABC news question. Do you have a health insurance plan? You're.

US ABC President Trump President Nicolas Maduro Democrats Venezuela Nancy Pelosi Al West Palm Beach Sunrise lake Sheriff Jason ARD Pook Livingston parish American embassy Dakota Caracas Tara Palmeri park Cody Weddell Louisiana president