9 Episode results for "Andrew Jans"
"Hill welcome back to the real life. Pharmacology podcast I am your host Air Christianson. Today I'm going to cover testosterone so testosterone is a medication used primarily in the setting of GME so essentially This is replacement where patients are deficient in testosterone now from a mechanistic physiological standpoint testosterone and its derivatives are found in the body. They're classified as in Anchorage Trajan in Andrew Jans or really responsible for a creating maintaining up male characteristics and the development element of male sex organs. Now you've probably heard about steroids primarily through Abuse if you follow Allo Sports Athletics Track and Field Baseball. You name the sport and Testosterone has probably been associated aided with it As a potential drug To be diverted and in addition to those male characteristics and formation mation of those male sex organs Anabolic steroids like testosterone promote muscle building. So you can imagine regardless of your sport if you're bigger faster stronger. There's potential for abuse of these agents so definitely keep that in mind with testosterone for sure now one really unique thing about testosterone her own and the commercially available products of testosterone. Is there a ton of different drug formulations. We've got got you know intramuscular we've got Topical Testosterone like Gels and Patches Oral injectable actionable as far as We've got a subcutaneous pellets. For example that are kind of time released delayed release of testosterone so multiple multiple different Avenues to deliver testosterone in those patients. That needed one really important and What I think is an important patient? Education point particularly with topical agents especially topical agents. That have have strong. Systemic absorption is that risk of incidental exposure To others that may be helping pick up medications indications or closely intimate with those that Are Using these medications. And they're on the skin and probably most concerning with testosterone Is it does have some negative impacts if a patient a female is pregnant and they're exposed to that so be really really careful in educating patients that that may be using the topical Gel or the patches that you know skin to skin Contact with that GEL or coming in contact with that patch. That drug is obviously going to be absorbed through the skin. That's how we're using it in pregnancy and we can have some really negative outcomes there so Be Extremely careful with patients. Be Sure to educate them. about Those risks especially for those Topical agents now adverse drug reactions from testosterone asteroid. So you can probably think of some of the things that maybe you've heard associated with the abuse of steroids or her Andrew Genyk Anabolic Steroids So I think Acne you've also heard the term Maybe heard the term road rage. So you can have some emotional Changes You know more aggressive agitated anxiety insomnia things like that can happen from Excessive doses of testosterone in certainly in situations of abuse where people people are abusing these for their muscle building purposes. But in addition to that. You know you might say well. Why don't you know we use destroyed a little bit more often? Well there is more risks than just superficial risk and testosterone. Ken Raise Blood Pressure. And with that there's definitely associations with cardiovascular risks things like heart attacks strokes To stop strong can also increase lipids So again there were were creating Maybe exacerbating multiple risk factors That could increase the risk of cardiovascular events in addition there's association with DVD N.. P. Risks as welder older so lots of potential negatives from the use of testosterone. So we need to be really careful. I need to be paying attention into the patient population that we might be using this medication in as well. So let's take a quick break from our sponsor and we'll finish up On Drug Interactions. If you're in the market for board certification study material if you're a pharmacist pharmacy student. I GO CHECK OUT ALL OUR RESOURCES MED MED. One zero one DOT COM Slash Store S. T. O. R. E. In addition to all those exam resources We've we've got clinical books. clinical education. We've got audible books as well promotion. We have going on. You can get your free your first audible book for free. So if you've never listened to inaudible book go check out pharmacotherapy or thrill of the case. both are are excellent clinical pharmacy resources where I've shared a lot of my case studies and clinical pearls things that you actually see in. Clinical Iraq is so great way to get a little bit of experience without actually being in practice. So definitely go take take a look at those resources. support our sponsor minute one one dot com and support this podcast real-life pharmacology as well getting check. ALL THOSE OUT MED. One zero one DOT COM Slash Store S. T. O. R. E.. So let's finish up on. Drug interactions out with testosterone. There isn't a ton of clinically significant drug interactions that you need to be aware of but I'll highlight a few here So what is it can increase Concentrations are there is that potential to raise those orphaned concentrations which which could increase. Irr there so in a patient that you're starting testosterone. You're probably GONNA want to check in I in our and they're on more for new probably GonNa want to check in our You know within maybe a week of starting that testosterone also educate your patients. Beware Hey you you know. You're at increased. Risk Bleed Bruise. I keep it keep tabs on that and definitely let us know If you're having any troubles or concerns in that department even now corticosteroids When we say steroids in clinical in healthcare terms we generally think of corticosteroids so for an asthma exacerbation for rheumatoid arthritis flare? When we hear steroids we I generally think of okay? Yeah you know. We're talking about corticosteroids to reduce inflammation when we say steroids to the lay public You may get different results. There may be patients that have been on corticosteroids in the past for inflammation and they may recognize that that's what we're talking about But many patients that haven't I've been on steroids. They associate Steroids with testosterone in drugs of abuse. There there is a potential interaction in between the two. And it's more of an additive type of fact particularly with the risk of Fluid retention and Dima so if you're using them in combination with one another There may be some additive effects there to keep an eye out for and then we do have some alterations in Kind of glucose metabolism and things of that nature so patients who have diabetes and are taking agents that had a either are insulin or Stimulate the release of insulin in the body we can run into some risks of hypoglycemia Ziemia. So pay attention in a patient that you know. Maybe they're on design. Maybe they're on a you know a long acting. Insulin like glare gene keep an eye on those patients. Maybe a little bit closer when we first start that testosterone. Could you may see a little bit of a drop in a blood sugar in potentiate. Hinchey eight that risk for hypoglycemia. So I think that's going to wrap it up for today if you enjoyed the podcast if you found it helpful do us a huge huge favor. leave us a kind rating review on itunes or wherever. You're listening so so appreciative of all that have done that Also go go to real life. PHARMACOLOGY DOT COM. Snag Your Free Thirty one page. PDF simply I subscribing To follow the the blog or the podcast cast when we've got new releases and new episodes ready for release so Once you sign up you'll get that free. PDF thirty one pages of the top two hundred drugs And I highlight Really important clinical things that actually happen in real life with if those top two hundred drugs so go check that out again. Totally free resource just for following the real life pharmacology podcast. So I'm going to wrap it up for today. Thanks so much to all of you who have supported our sponsor met at one one dot com. If you haven't done so yet again go check out. Those resources there met at one DOT COM Slash Store S. T. O. R. E.. And thank you so much for listening take care and a great rest of your day.
Lisa Selin Davis: ...the history (and the future) of girls who dare to be different
"Support, for this podcast comes from state farm with surprisingly great rates. State farm is the real deal when it comes to home and car insurance state farm agents are always ready to help you personalize your insurance plan. You can create a policy that fits your needs. You can manage your coverage, pay your bill or even file a claim right from your phone with the state farm mobile APP, and you can always call one of the state farm agents in neighborhoods across the country. Get a great rate without sacrificing great service when you want the real deal like a good neighbor state farm is there. Welcome to nobody told me I'm Jan Black and I'm Laura Owens as a mother daughter duo. We're very much looking forward to this episode where we're talking with our guest, Lisa Sellin Davis author of the new book Tomboy, the surprising history and future of girls who dare to be different. The book explores where tomboys fit into our evolving understanding of gender identity and expression, and it expands on the ideas least I discussed in an op Ed piece she wrote for The New York, times, about her own daughter's experience as a self described tomboy least. Thank you so much for joining us. We have so enjoyed reading the book. Thank you so much for the copy of it. Thank you so much for having me for enjoying the book. Talk to us about that New York Times piece that inspired the book, and you also dealt with a lot of criticism for it. So talk to us about how you dealt with that. Well, that was definitely my first twitter storm and it was interesting because I had written this piece where I was expressing. What I thought was poor for Trans Kids in saying yes absolutely. Let's facilitate them and support them. But also pointing out that although there are also some of these cysts gender kids, girls who kind of dress like boys are like boy stuff or play with boys, and how can we support them at the same time because when you're telling a girl like that? that. She must be a boy. It seems like weirdly regressive in this era when we're supposed to have such expansive notions of gender. And the first time I had written about that was a few years before and really no one was talking about trans kids in the media just wasn't a a subject that was getting much press but. This time because it was in the New York Times because of the somewhat didactic headline which was My daughter is not transgender. She's a tomboy which really rubbed a lot of people the wrong way. There was A. Very, impassioned response and even though I say in the piece I don't know if she's she could end up being trans but. I don't want her to get this message that because you like what's called boy stuff that you have to be a boy. And I did not know that I was stepping on a lot of toes and stepping into a really fractious debate between people with lot of stakes in game I just didn't know that existed which was. I, don't want to say a war but a battle between some feminists and some trans people and some ideas of whether or not man or woman is a biological category or social category although stuff we kind of saw played out with J. K. Rowling a few weeks ago. I didn't know about I didn't know that I was participating in that by what I said. To then I became. Curious about what I had stepped into and wanted to know more about it and understand it. Will tell us how your your daughter came to self describe her herself as a tomboy. Word for her and. When they're around three, you'll notice that they really start segregating into groups mostly by sex mostly girls start playing with girls and boys with boys. It's also a time when some kids won't conform sometimes those kids are coming out as trans and it's about identity, and sometimes the kids are just not doing what you think they're going to do because of their body parts right now I understand that since I've studied some psychology around it that it has to do with trying to sort of perfect what group urine, and that's when kids start gender policing, teasing each other and really internalizing gender stereotypes. So my kid was not doing that and we didn't know why. The girls were getting heavy into the princess phase and mine wasn't and I didn't ask a lot of questions about why. But I kinda monitored my feelings about it. And as a as someone who was born and raised a feminist, and then in first grade, she came home and said Oh I'm a tomboy that's somebody who likes sports enhance your hair. That's girl who likes worse in his short hair. So it was clearly something that other parents had been discussing with their children at the school right and someone must have explained to a kid. Oh, that's a tomboy. And we had them all the time when I was a kid. So part of it was like wait why Why was my childhood filled with girls who looked and played like that? Why were they? Why were they the heroines of all the TV shows and movies that I watched what happened to them? So it's really the combination of of the conversations I had after the article and the awareness that this was a common trope that was mostly gone today was those two things together that made me think there's really something really something going on here. That's worth investigated. I thought it was so interesting when you started research for the book that you found out how many different ideas and definitions of tomboys there were tracing back to the time of Shakespeare where a tomboy was not thought of to be such a great thing and then as time went on, it was maybe thought of as a little bit of a better thing and it kept switching back and forth and it seems like there's never been any real firm definition of what exactly one is was your sense as you continue to research that that was more at the truth than you thought. It was really fascinating to. Be Forced to look at my own assumptions so. Especially when my kid was doing what I thought was boy stuff. And then and then I you know even someone who is kind of raised hardcore feminist I wasn't saying wait. Is that boy stuff and who decides what's boy stuff? Yeah, and looking back. Over the kind of last hundred seventy or eighty years and seeing how things were divided into boy and girl, and how every time you do that anything whether it's colors or toys, personality traits anything you divide like that. There are going to be kids who are who are not going to abide that divide and. Because they want something on the other side, because it's more fun like putting all the physical activity, the boys. And then you get a girl who wants you do physical activity and you either thank you know that there's something unusual about it. But if you divided the stuff that way, right it doesn't have to be unusual if you if you stop `gendering that stuff. So what's fascinating is Looking back over the years at what gets divided that way and what girls and boys are encouraged to do in different time periods. So in the mid eighteen hundreds of lots of girls climbing trees in playing baseball by the time you get to the nineteen seventies. There are so few girls playing sports that there has to be a lawsuit in title nine, and you you have to work on getting girls to have access to this stuff that may be in other terms would have been seen as perfectly natural. And you know the same with the colors pink you know when we start producing pink more as a color in the early twentieth century and then they think pink people say, Oh, Pinkas for boys because it's connected to read and run his masculine and how that stuff gets battled over. You know between generations about what's masculine feminine what's for boys and girls, and what's normal, and it's really interesting to ask yourself where your ideas of normal came from who made that up for you. Know Yeah I. Know You say you learned that childhood tomboys grow up to claim many different sexualities and gender identities explain more about that. Well. There are there are a lot of when I look at the research, the psychological research about tomboys, there is a a ton of it. There were lots of people looking for connections between Tumblr is. Being. ISM or Tomboy ISM and transgender identity as well as things like Tomboy ISM and self confidence or Tomboy job choices, and there have been studies that found some correlation between identifying as a tomboy being identified by others as a tomboy growing up to be a lesbian or bi or pan sexual or going up to identify as a man or non binary, and then within those studies, there are plenty of people who had the same kind of origin study who grew up to identify as straight or SIS. Gender. and. What I ended up feeling was. that. Trying to draw these direct lines between the way you express gender as a child and how you're going to identify. Later, I can understand why people want to study it. But it's actually still part of the narrowing of choices and identities and ideas for children that the more we can encourage them to explore and to explore what's on each side of the paint blue divide regardless of identity. More psychologically healthy they'll end up being. Our nobody told me conversation continues in just a minute after we tell you about better help online counseling. You know you're not alone if in these times of uncertainty, there are issues that are interfering with your happiness or preventing you from achieving your goals. We've certainly experienced that ourselves if you have to better help. Counseling is there for you assessing your needs and matching you with your own licensed professional therapist better help allows you to connect with your therapist in a safe private, convenient and affordable online environment. You can start communicating and under twenty four hours. This is not self help. It's professional counseling. You could send a message to your counselor anytime and get timely and thoughtful responses plus you can schedule weekly video or phone sessions. Better. 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P. dot com slash nobody better help dot com slash nobody. And since it's such a complicated issue now seeming like it's so much more complicated than when my mom was younger girl just considered herself to want to run around and have her hair in a ponytail and that was a tomboy and there was no more anything about and it was just that who you are. Yeah. But now it's become so much more complicated. What advice would you have for parents who were in your situation with girls coming home and saying there tomboys mean you want to approach it the right way but what is that and what should these kids be saying to their friends? You may be are bullying them about that. Those are interesting questions and my feeling after reading this was I really wish I knew this stuff before I had my kids I I wish someone in these parenting books had been a discussion of how children learn about junior. And just in the regular parenting book and I wish that the pediatrician had known something about it and I wish that I had been encouraged to. Say to my children. Nothing is off limits for you. Because of the body were born in or how you identify. So the things that you're gonNA see walk around in the world and you're going to see things marked as for boys or for girls. People are gonNA. Tell you boys are like this in girls are like this people are GonNa, make assumptions about who you're GonNa WanNa play with and what could've activities you're going to want to participate in. And we don't have to abide by that are stalls. We don't have to live by those rules were not in my house. We don't have. We don't gender colors we don't gender toys we don't gender activities. Everything is available, but you you really have to fight against the messaging that the culture gives you an especially the marketplace, right 'cause it's a tell you sell stuff is you have pink and blue versions and you sell twice as many so. It's really about counteracting the gender stereotypes that are forced on our children. Now, from before, they're born because of prenatal testing and gender reveal parties right that pink and blue divide starts before they're born now. Yeah. So yeah, I. Feel like it's What I WANNA do is to really change the culture, but parents have to participate in changing that culture by making different choices by not limiting their children and by really trying to counteract the messages that we all absorb and participate in spreading. You ask the question are tomboys born or made, and I'm wondering what you've come up with the answer for that. Answer is both. The answer is. There is some research that shows some kind of link sometimes between testosterone and other Andhra Jains, which we think of as male hormones. But of course, we all have estrogens and Andrew Jans. We all have quote unquote male and female hormone circulating in different amounts that do a lot of things besides helping with secondary sex characteristics. We all have these hormones they do lots of things and some times. There's a little bit of a correlation. Amount of testosterone perhaps like spatial relations are interested in sports. You can find that science. I'm Ben. You can find that say like maybe some of these girls who like the staff have slightly different hormones than typical girl's let's say. but you could take a lot of holes in that research and there's even more research really good research showing that when you really really work at providing children with counter stereotypical models and images that they can not fall into the trap of gender stereotypes. So if you show kids. Pictures of little boys playing with my little pony in and saying I love my little pony. Young children will think that my little pony is a boy's toy. So you you can really affect. WEHR choices by working against the messages and so you can sort of quote unquote like make your kid do a certain extent. You can make your kid at least still open to trying things whether you can make your kid into a person who has certain interests or abilities I mean I wish. I. Knew that part of parenting so much better at this. On. But certainly It's a combination of are these kids facilitated in their interests are they supported? And do they have access? Do they have counter stereotypical messages and yeah they have some kind of innate desire to be that way probably that to talk to us a little bit about pronouns because that's been such a hot topic in the last few years with people. Now signing their name with a Pronoun do you think that we should encourage children or or even ourselves friends whatever to use a certain pronouns to describe ourselves just the one that were born wet. So she her for me or should we encourage everybody come up their own and see what they identify with? That's a great question and I, sort of want to plead the fifth on it but. I'm very interested in the different camps on this and so in the book I interviewed a woman who is raising her child with them pronouns. And the child has a sex marked on the birth certificate but almost nobody knows what that sex is. Maybe the preschool teachers and that child is being taught that there is nothing for boys or girls including body parts, right? Wow. No I'm mostly I'm mostly I've been focusing on material culture and personality traits, the toys the closed the colors. The ideas that boys are rowdy girls sweet, and in addition to that that parent is focused on. Also, let's not also listen on gender bodies. You know that you can be a girl with opinions boy with a vagina and a non binary person. WHO's Intersex and has both parts of both kind of bodies and I think what fascinates me and what would I want to focus on is who gets liberated by these advancements and who gets impressed by them, and that's the question I'm asking over and over about gender. In these new understandings, if we have seventy two gender identities who's liberated by that, but an, who for whom is that were difficult and because I'm so focused on gender stereotypes in the hyper `gendering of childhood that becomes less important to me individually and my mission because I think what I'm doing is creating more space. And if we muddy the pink Ludivine and make him agenda and let kids try baseball and ballet and wear dresses in pink sparkles and sweat pants. then. However, your gender identity develops whatever pronouns who use there's more room for you to experiment as a kid. And I think that some children are really adamant about their pronouns and who they are sister kids and transgender kids an-and their kids kind of don't care who feel like what you call. Me Doesn't affect my sense of self and it's interesting to look at both those groups. How do we find peace and consensus among people with competing agendas? You know that that's what I'm interested in but that's why I feel like focusing on the kind of. Hyper `gendering of childhood. Is more important to me than focusing a lot on pronouns. However, I absolutely use anybody's pronouns that they want me to use and have put pronouns in my signature on my email as a kind of way of being an ally. 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So I'd set up Google alert for Tomboy that was the very first thing I did and every day the celebrity profiles for coming in. Of Janet Jackson Janka Chopra and Katherine Hepburn and Julia Child and famous women of the nineteenth century and. You know the first woman doctors and surely cushman aggrieved actress and. It was amazing that all of these women said, they were tomboys when they were little and nobody really knows why that is but. I have some guesses. One is that I think a lot of these girls spent their childhoods with boys and were often perceived as and treated as boys. And so they got a comfortable in male dominated spaces, which certainly helps if you want to be successful in life. Forward and And you know they may have had access to a certain kind of male privilege. This happens with my daughters when I'm with my daughters all the time. And the older one is referred to as buddy. And the younger one is referred to as Sweetie. And you know one is thought of as kind of appear an equally another one is a cute little object and they're both technically girls. Females, and so I, think these tomboys are treated really differently and that affects them. They don't get the kind of quiet sexism that calling somebody sweetie pie as opposed to buddy. Where does that? That's the beginning of it where does that lead eventually so? I also think that a lot of them when they grew up, they might not have called themselves tomboys a kid a might not have even liked that term but looking back. They. Think they. They Keno what I was a tomboy and it's a way for them to press. I was always different from the other girls. I was always exceptional. I think those two things can be happening. Who is somebody that we may not know about that maybe you learned about during your research that you think made a big difference in terms of challenging gender. Boundaries. That's a good question I mean. I was really surprised to find how important little women was. And how important Joe March was, and you might not be surprised by that because you know they just yet another version of the mood been made into many movies and it's never been out of print. Obviously, it's been an important cultural artifact. But what I didn't know was that in the nineteenth century when the field of children's literature was starting to take off as more middle class kids were getting educated. The country's very first bestseller apparently was a book called the hidden hand by Eaten Southworth and started mischievous tomboy called capital of black and it was such a hit that all the publisher said we've got to get more of this tomboy literature and then came little women and that really changed everything and. Joe March was so beloved and to this day, right she's the heroine of it and she's the one who's burning her dress and chomping on her hair and refusing to get married to the nice slightly effeminate boy next door. She's the heroine and so I mean it really. That literature and the first wave of of nineteenth century girls who were raised as tomboys. My suspicion I didn't see scholarship on this, but I came to believe that bill is girls became first wave feminists are the kind of white feminist of the suffrage just movement and working however problematic that our first wave feminism was of whoever it left out I really think it was fueled by the first generation of girls raised with the idea that they deserved equality with boys. Interesting you know I always think of scout finch in to kill a mockingbird as as being a tomboy and and heroin I mean I think that's another great example. Absolutely I mean that was until recently thought of as one of the if not the greatest work of American literature which is being contested now because you know it's really a story about like white saviors but but. Scout you know is, is the one really telling that story and scout is also refusing much like her father sort of refusing to participate in a certain amount of systemic racism. She is refusing to participate in a kind of systemic misogyny and sexism that says who she supposed to be, and that's why she's the heroine right because she's not. She's really not punished for it. She's beloved for it. And Lisa, at the end of each show, we always ask our guests. What is your nobody told me lessons so like you mentioned, there are a lot of things that you wish you knew. Before your six year old then six year old daughter called herself a tomboy. But what lesson would have helped you the most it really would have helped me to learn about how kids begin to understand gender and their role in our society and that. The princess phase. is temporary but was at the end of it. When girls start rejecting princesses is even scarier which is about when. When they start kind of internalizing sexism as you boys and we start with all this stuff that's marked as feminine. And when people are to say like I, hate pink boys and girls often go through this phase later on I hate princesses I hate pink do that's girly using the word girly as an insult I really wish that someone had told me you don't have to participate in any of that. You don't have to see paints girls color or a boy's color, and you certainly don't have to denounce things because they're associated with girls. And the other thing I'd say is fat I get notes from parent saying you know my daughter am worried my daughter is seems to be gender non conforming and I don't know what it means and I expected her to be this one way and she's doing this other thing and what should I do about it and what I usually. Say is the research about how healthy these like kids who naturally resist gender norms are. There's a study that came out last week that boys who will have feminine attributes girls who have masculine attributes do better in school gender non conforming kids tend to perform bettering all of these ways because. Or hurtful. So what I say to parents when they say like, what should I do? Is celebrate you looked out facilitated celebrate. And Lisa how can people connect with you on social media and the Internet? Well. I'm on all the all the things with at least Davis at facebook and. INSTAGRAM and twitter. I have a website Lisa Sellin Davis dot com send me a note celebrate and facilitate with me. We'll listen we thank you so much for joining us. This is really been informational and and we love hearing the story and all about your research, and we wish you and your family all the best. Thank you so much. Thanks for the great questions are thanks again to Lisa Sell Davis, her latest book is called Tomboy. And Future of girls who dare to be different and again her website is Lisa Sellin Davis Dot. com. I'm Jan black onto I'm more owens you're listening to nobody. Told me thank you so much for joining us.
50. How to Wear Body Hair, Part 2
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That's the real real dot com. Promo code real. My version of letting grow would mean me having a different body, basically, I don't quite feel like I'm up for the challenge of walking around and be like, yeah, totally. I have a beard, whatever. Recommended reading. Right on ninety. Hail and welcome to unladylike where we find out what happens when women break the rules. I'm Caroline, I'm Kristen. And this is episode two of our three part miniseries, how to wear body hair. Short short short short. Short cut Kristen, if only the most complicated thing about body here was the length of our shorts. It turns out the most complicated thing is figuring out how to get that in their commercial out of my head. Caroline true. Okay. So last week Caroline unite talked about all of the pesky patriarchal, and frankly, racist rules that constructed, this whole idea of the feminine hairless ideal and this week. We're going to dive deeper into the feminism of it all. Yeah. Because sometimes it feels like feminism has conflicting rules around all this. So, you know, to psalm being a true feminist means giving no fucks about patriarchy beauty standards telling us to shave every single stray hair on your body to which other feminists rules, say my body my choice. I'll let it grow if I want to and for me, personally Carolina, that whole argument leaves me at a loss, because I, I don't think they're just making up my mind equals feminism. Yeah. And honestly, the back and forth leaves a lot of us feeling confused and even guilty like listener Rebecca, so Rebecca tried going, Harry. And then. Told us that when she quote gave up in shaved she actually felt like she had failed. Yeah. And the idea that shaving makes us failures is just as much bullshit is the idea that not shaving, somehow makes us superior feminists. And so today, we're exploring this gray area often overlooked in feminist debates over body hair and patriarchy smashing to amazing unladylike listeners are going to help us explore what it feels like when a binary body hair conversation. Ignores your spot on the spectrum our first guest, Jay. We'll tell us what happens when you're feminist. Roomma- catches you laser in the apartment. And then our second guest Alice is going to tell us about her journey, negotiating with body here on the path to embracing her gender identity, and you might be surprised our feminist mom reacts to it all pull us. We're going to go back in time to figure out where the idea that not shaving makes you a better feminist even. Came from so, like wax to a leg stick with us. Short hair with baby oil near with L O VERA, and you narrow non for bikini area and underarm. So probably a question you don't get very often. Could you describe your body here? So. Gosh, where to start. This is an unladylike listener were calling. Jay J. I used to go by j when, when I was ordering coffee in the states. I talked to Jay by Skype from where she lives now in the Netherlands, and Jay wrote to us because, well, she's Harry, I have hair on my chin, and on my neck. It's sort of continues on as at wants to. I don't I think maybe like how play down my thighs, and then I just have leg hair, and basically here everywhere, inner Email, Jay said, there was one thing in particular. She really wanted to talk about what it's like to position yourself in the body hair, positively narrative, when your body hair is unruliness beyond the point of what people expect it to be jas families from the Middle East and Mediterranean. Her skin is on the lighter side, and her course, dark hair stands out. She was constantly teased at school. She was always the Harry one even her sister's hair wasn't the same in early teens when she started getting facial hair J knew something was up literally yesterday is my, my got officially diagnosed with Pecos for the first time yesterday yesterday. Really? Yes yesterday, so I've been going to the doctors since I think fifteen was. First time I went to the doctor's with us, and they said, yeah, you probably have pick us about. There's nothing that we can do about that necessarily poly cystic ovarian syndrome or Pecos is a hormone disorder that affects an estimated one in ten women and people with uteruses a primary symptom is high levels of Andrew Johns, aka male sex hormones like testosterone. And those Andrew Jans mean your body hair is probably going to grow in darker coarser, and in places like your face neck and chest. And by the way, it's not just Pecos that can affect your hormones and hair growth, menopause, pregnancy, thyroid disorders, as Szekely if it throws your hormones outta whack and reduces your estrogen chances are it's gonna have some effect on your body hair and beyond for j her hormone fluctuations can also cause skin irritation, which in turn makes it harder to shave. So my options either acne or hair because if I would shave my face, though, it would that would mean like walking around with the concept breakout. When it comes to choosing to remove her body hair, Jay feels like her hand is forced like sure she could choose not to remove it. But then she'd be gawked at sometimes it even feels like her doctor is telling her what she's supposed to do with her body here. She said like I can see that, you know, the hair growth on your face that, that's becoming more prominent, and it's probably bothering you can see that you're not shaving it, and it was like to hear that from a professional that it's noticeable and that it seen as a choice. It really sort of moved something in me sort of made me realize exactly how, how much there is an expectation that if we have hair in a way that is obvious. We need to to remove it. We need to shave it away. And I thought my naive mind, I thought that was being very that he was my private thing that it had nothing to do with the outside world. But of course, it doesn't chose people notice. People see people around Jay. Also get political about it. Jane, or friends are pretty active in the feminist scene, where they live and the prevailing attitude toward body hair is if you wanna stick it to the man, let it grow, which J, obviously, feels a little complicated about and things kinda came to a head for her with one of her old roommate's. This woman didn't shave and she also talked about her own body here as if she was like, yeah, but I have quite a lot of hair, and I don't remove it. And I would look at her hair, growth, and really that's so you need a whole lot of hair and that was around the time that I was I was getting so frustrated with my own hair that I literally secretly. I didn't tell anyone I saved up for one of those laser hair removal lasers that, that you can use at home, but I didn't tell her, but the thing is, you can't quite laser a home in secret because first of all those things are incredibly loud and. They flash. These super bright red sort of infrared flashes into the room, like if the doors closed and the other person is on the other side of the door. What you'll hear is a small engine, and then like flashes of light coming from under the door, I would just assume by the way that you had like a wild new vibrator. That would have been. She would have supported that. But so I, I usually lays it when she was gone. I'm sorry, I'm just really stuck on the image of a vibrator that has flashing lights. Amazing. That's the disco lighter. So like Jay said normally she laser when her roommate wasn't home, but you've got to do it regularly at specific times, and this one time, the scheduling meant that her roommate was right outside her door in the living room. And she, of course came into moments just like the fuck. Is that noise? What is this, this going euro, and I tried to be cool about it. I'm looking, I'm just lay there in and exactly the conversation that I was afraid was going to happen happen. She was like, I can't believe that you're laser I can't believe that you're doing this year body in order to remove hair. Don't you know a way you know, she's tiny wants us to remove haired, you know, the history of hair removal, all these things that we talked about a million times. So she knows I know in the end, she, she said, like, I can't believe that you like the most feminists person I know that's what you said, are doing this, and it. Hurt not because it felt true it hurt because I just felt completely lost. I felt like I was talking to somebody who couldn't en- wouldn't understand what was going through j also felt angry. She's frustrated of having to explain even justify her body to people whose bodies are different from hers, and less hairy. If I were to just let it grow as at once, then it will mean a beard, it will make me visible in a way that I don't think my friends will. No, I know I know that my friends don't deal with. It's not something that anybody especially not here in Europe. Especially not in the city that I live in which is incredibly white, it's not the kind of body that people see very often. It's not the kind of body hair that people are very used to is there, a healthier or more productive way that feminists in particular could be talking about body hair, sort of ways, we can change this narrative. Yeah, I think it'll be be really nice to hear more acknowledgement that the narrative that we have around body here is very much centered on white bodies and relatively hairless bodies, and, like, also like in, in romance, novels even like when, when bodies would masculine bodies like attractive, masculine bodies are described the focuses on hair as well. Like they talk about the happy trail, like a sexy little. Rail, and I'm just like I wish I could look at the hair below my Billy button milk. Oh, yeah. That's a sexy little. That's a beautiful little trail. Jay wants to move past the conversations like she's had with her roommate that focus on a very specific kind of hairiness and towards conversations that include the part of the body here spectrum that her body fits into she got a glimpse of the power. These conversations can have a little while ago on vacation with her sisters and some friends, one of the other women on the trip also had hair growth on her face, and she approached Jay. We ended up having conversation about what it's like to have very visible hair growth on your face as the woman. Is somebody who presents his a woman, and then won't point she said. That she looks at we that she really likes the way that it looks and I had exactly the same. Like I looked at her, and she's like she's gorgeous. And the way that it's sort of the, the side beards. It just looks I thought it looked really just lovely and very beautiful in its own way. And it's really hard for me to feel that way. When I look at myself in the mirror, and it was really nice to hear that she had the same experience in that. She saw me in the same way that I saw her, and it also made me realize why this is so difficult because I I'm kind of alone in this in my environment to my community. And if I wouldn't be alone in this much easier, it will be to be proud of this, how much easier it will be to, to feel empowered in this body, I guess, Kristen can I just say that everyone deserves to feel empowered in their bodies or at least okay with their? Bodies, no matter what their hair looks like. And we need to find a way to have a conversation about feminism and body here that helps that happen rather than, you know, like completely hindred. I totally agree. Caroline. That's why after the break you and I are going to unpack the claptrap on hairy feminism and the important ideas of this whole just choose your choice thing doesn't make room for stick around. 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So go to Honey book. Dot com and use promo code unladylike to get fifty percent off your first year. Get paid faster and work smarter with Honey book dotcom, promo code unladylike. Seattle is a city rich with textures characters and soul, it fosters people's motivation to change the future of culture for good. Join visit Seattle and tastes made as they celebrate Seattle's one of a kind culture with a brand new five part podcast series uncharted Seattle over half an hour host and entrepreneur. Linda Dirshane sits down with some of Seattle's most passionate creators, bringing new life added depth and captivating insight into those who are at the forefront of their industries in each episode. Dirshane talks to guests about why they end their work a thriving in Seattle, and what makes this city when to watch because these people don't just happen to be in Seattle. There's just simply no other city where they could thrive. Learn more about how passionate creators are shaping the culture and soul of the city and listen to uncharted. Seattle today, then go visit Seattle for yourself. Available on apple podcast at your or ever. You're listening right now. Some totally practical reasons why breaking body here rules mix feminists. Oh, sure. I mean, I'm a feminist who shaves and it costs me time, money, energy Bandon. And yet, I still do Caroline, what we're curious about though, is how hairiness became this sort of purity test for feminism in the first place, because hearing that story about Jay's roommate raises a lot of red flags for us as feminists because if someone in the name of feminism is disappointed in you because of how you are grooming, your body here that, just it doesn't feel like actual feminism is that making sense. Yeah. And it does make so much sense that I feel like it's time to unpack some claptrap about it unpack. The claptrap is the part of the show where we tweezers out patriarchy's Yuna, brow to find out. Why things are? Are the way they are. And today, we specifically wanna to know where the idea that not shaving makes you a better feminist came from. So let's get started in the nineteen. Seventies, you know, hairs political. You've got afros you've got hippies with long hair and beards. And so it's honestly, not surprising that feminists are getting in on that political hair action to write. But instead of growing out their head hair or face hair, feminists were all about growing out that leg and hit hair, and this was such a feminist issue at the time that in July nineteen seventy seventy-two the very first monthly issue of MS magazine hits. The news stands, and y'all may have seen this issue before it's kind of a conic now wonder woman's on the cover with this headline, wonder woman for president and she saving everything. And in the top right corner, kind of right above her giant superwoman hand. There's the headline buddy. Where the last frontier to today, the authors Harriet lions and Rebecca Rosenblatt. I tried to get this published in cosmopolitan, but even Cozma was like, no, this is a step too far even though Caroline, what is hilarious. Is that just a couple months before cosmopolitan adjust publish that centerfold of a nude Burt Reynolds? Who is about his hairy as they come. He was about as Harry as the bear rug that he was lying. It's true. So even Cosmo which was like totally cool. With all Burt Reynolds is chess, there was like a leg hair on feminist. Get outta here. The hair too far but not a hair too far for MS magazine. That's right. So in this three page manifesto, Rosenblatt and lions were essentially pining for a feminist future win, quote this small but intimate tyranny. Will be resisted tyranny. Meaning like, girl, you gotta be smooth. Yeah, because okay we also have to put the context of the time. We're living in a very hetero. Normative leave it to beaver if kind of age, even though, of course, all of that was starting to be challenged. But these feminists were saying, look, we're already having to raise the kids and do the dishes and look pretty for men, and then we also have to remove all the hair from our bodies fuck that, but their most important kind of underlying argument for the whole thing was not just thumbing their nose at the male gaze, but also as they put it affirming, our natural female Ness, essentially saying that when we are shaving off, removing our body hair. We are removing a part of our natural essence as women and keep that idea of the natural woman in mind, y'all and not shockingly, their essay kind of went old school. Viral. It created that Harry feminist as the symbol of women's lib, and radical feminists that we're so familiar with today. Yeah. And since there wasn't Twitter or comments sections, we did have letters to the editor to hear about how people were so up in arms over these hairy feminists like this one Bersin in nineteen Seventy-three, who wrote the New York Times complaining about armpit feminists women whose involvement with the ethic of body hair has overpowered other considerations in one thousand nine hundred seventy seven twenty thousand women convened in Houston, Texas for the national women's conference, and one Texas legislator called these women hairy legged zu girls, which to me, Kristen honestly, just sounds like a really cool band, or like a group of gogo dancer, but in reality like it wasn't like women everywhere, were flushing their razors down the toilet. Like, in fact, a couple of years before. For that Texas legislator was railing against those hair leg, Zuber leg girls. Whatever the New York Times reported that American women were back to shaving legs. And it only quote core group of militant women were still hanging onto their leg hair, reinforcing, this connection between radical gender politics and body hair. And this whole core group of militant feminists was considered such a cultural blip, that Gillette was like, hey, the wrist of you, ladies we're answering this whole freedom business by putting out more razors. Here's a lime green fashion razor to, I don't know match your purse, or, you know, give you another choice to choose, but regardless of the lime green razors. Caroline, the stereotype of the Harry feminist stuck around, or should I say kept sticking around because the whole idea that calling a woman Harry is an insult is sort of misogyny at its lazy. Issed patriarchy's, go to insult has always been to call a woman manage, and therefore, not desirable to the male gaze. And what worse of a thing could you be? Yeah. I mean, all you have to do is look back to the suffrage movement. So in the nineteenth century punch magazine always ran these lake political cartoons. And they were, of course, very fond of lampooning suffrage ists. And there was one cartoon that had speech bubbles like my hair is dark chestnut. My moustachioed us our rather lighter. Of course, again calling suffrage just manage, because surely that would scare you away from feminism. That's right. Because of you hang out with those ugly old feminist men aren't going to talk to you. I like the moustachioed sounds like cereal though. I need some mustaches can hungry. But the thing is the Harry feminist has stuck around. It really became synonymous with being a man hater in the nineteen eighties amid all of the conservative backlash to the whole. Winging seventies movement because the argument that was then adopted by both men and women alike was idea that no no the natural thing for a woman is to want to be attractive to men otherwise that just makes you an up tight, lesbian feminist. It's interesting to, to see that from the nineteen eighties really to the twenty tens, the amount of hairless nece that women really focused on arguably just increased because Carolina. I don't know about you. But I feel like we spend at least all of the early odds, just debating pubic hair. I mean I know that's all my family debated around the thanksgiving table. But it also seems like during that time the feminists debate evolved beyond like, okay if you're going to be a truly committed feminists, you've got to throw away your razors flipped to okay? Listen, radical feminists. I'm also a feminist but I can also share because I choose my choice, therefore that is feminism, but choice assumes that we're all dealing with the same potential consequences of growing or not growing our body here. It's also assuming that all of our body hair grows. Exactly the same way, which, of course, makes me think of Jay right? Because she feels so overlooked in these feminists conversations because a lot of times, we're applying a binary choice of either exercising agency or somehow being pawns of patriarchy by excessively grooming ourselves. When, in fact, like we're not acknowledging the spectrum of bodies and identities. That interact with all of this messaging that is projected onto our body here. So I think it's important to keep in mind when we're considering what to do with our body here in the idea of choice that actually living, it out is a lot different than like theoretical gender politics. Yes. And I think that's the critical point right like that. We can talk and we can debate all day long. What's right. What's wrong? What's powerful and empowered. But ultimately, we can't forget the actual human people who are living in those hairy or hairless, or somewhere in between bodies every day. And it also underscores the fact that I don't think that we have fully moved on from the underlying assumptions in that original body hair final frontier manifesto that we are specifically dealing with usually white. Middle-class SIS gender Bem identities here, like there's kind of no broader room beyond that. And I think until we are actually considering the entire intersectional spectrum of our lived experiences. We definitely can't prescribe something kind of blanket, body hair, grooming regimen for women. Right. And if we do all that does is exclude women, like J Rey. And speaking of j, there, one part of her Email that really stood out to us where she wrote where I do find understanding and friends who have gone through similar things is with my trans and gender, queer friends. And they're I struggle with the fear that I'm hijacking a narrative that isn't mine that I'm intruding that the overlap in the ven diagram of our experiences is to fractional to engage, but you know what? What inspired by j? Let's engage. Yes. And our next guest is going to take us deeper into that ven diagram. I'm transgender and my body hair has always been a place of severe discomfort for me. This unladylike listener. Can basically track her gender transition by what she was comfortable shaving. And after the break, she'll tell us all about that journey. And what she thinks is missing from the feminists body here debate. Stay with us. Looking good shouldn't break the Bank or the planet. That's why threat up the largest online consignment. Thrift store is on a mission to get people to think secondhand, I, plus threat up is offering unladylike listeners a special offer for an extra thirty percent off your first order, when you go to threat up dot com slash unladylike. That's thirty percent off their already discounted prices and Carolina. I got a box of threat up goodies recently including a vintage. Diane von Furstenberg silk dress, some Cole Haan shoes. And it did not cost me a pretty penny. Y'all can stay on trend and on budget with clothes accessories, and shoes from top brands like made well Lululemon ever lane, and more for up to ninety percent off estimated retail for a limited time threat up his offering unladylike listeners, an extra thirty percent off your first order. When you go to threat up dot com slash and like that's on top of the already low prices so hurry up and take advantage. That's T. H. R. E. D U, P dot. Com slash unladylike threat up dot com slash unladylike for an extra thirty percent off today. Terms apply. Do you feel like they're elements missing from a lot of those feminists body hair debates? Well, I think, but usually the things that are missing are the acknowledgement of the bodies that aren't deemed like conventionally attractive. We're back with an unladylike listener going by her middle name today. Alice, like, oh, sure embrace your hair. But if I were to like walk down the street with. The amount of hair that was on my body like before treatments before shave inner before hormones or anything, people would be like aghast, and I would feel bad and everyone else would like not enjoy that. And that's not part of the narrative, the narrative doesn't have that, like embrace strands women's bodies. They just kind of like oh, conform conforming is exactly what Alice's mom did not on for Alice's sister growing up. My mother was fairly anti shaving. So that was something that she did try to steal my sister. My mom believes that women shave to look pretty for men and that society and big razor terrible. You'll know big razor like the shaving lobby telling telling you tonight, more racers than narrow and stuff and picturing them like coming at you like. The capital with, like a bottle of. Nair. Sure. Angles all those. Racers don't run with razors. So anyway, Alice's body hair was blonde dish brownish and not terribly thick, but she couldn't stand it. Because by the time Alice was sixteen. She was finally starting to put words to emotions, she'd been feeling around her gender identity, and it turns out that shaving was the way that she could experiment with that in a private and temporary way, I would shave or tweet, like just like small rectangle of hair on my upper thigh just to like, do it, but I didn't want to shave all of my legs because I felt that people would think that was weird. I don't think I knew why I liked it. I think I just did it by seventeen or eighteen Alice started shaving her ankles, and she justified it by telling yourself, you know, I just don't like the way my socks elastic pulls at my leg hair. This was after, like I had sort of become come to realize that I was transferred. But here's before I actually transitioned so was kind of a lot of combination of embracing things and also partially denying the reason I was doing it and not wanting to embrace too much because like. Kind of being scared to transition. But then one day in college Alice's taking a shower and make so bold move. So I think it was just kind of like I'm already doing it. Oh, I shave too much. Like I went to high. Let's just keep going and. And. And then it was kind of this great feeling, but then also a little bit of like this nervousness, that somebody's going to call me out on it. So I just started like making up excuses of like, in case someone was like, why are your leg shaved could be like, oh, I think about swimming, sometimes so I shared, my leg, something like that. Yeah. So is that mixture of anxiousness and just absolute pleasure for Alice, her natural body hair growth, plays, a huge role in the dysphoric that she's felt towards her body, the debate over whether or not shaving makes you more of a feminist, does it really make room for Alice's complex feelings about her body seen those signs that like indicate? That I'm trans and being trans like is scary and being in public and not knowing like how you're perceived, and trying to minimize all those although stuff that's going to get you, clocked end. It sort of just always brought up this feeling that, like, oh. I'll never pass. And just like these little dark hair is on my shoulder. Could just remind me of that. And then as as I got over that it was sort of also getting over. Gain over and embracing my gender, and through that embracing shaving more and more parts of bodies that I didn't want the have to see with hair on them. So als kept shaving everywhere, to feel better about wearing low cut shirts, or dresses. She do some maintenance shaving like every other day and some days, she devote a few hours to take an off just everything in the shower, but being who she is, and growing up with the messages that she did Alice also felt a little bit of guilt about her shaving routine like way. Wait shouldn't. I just accept my body isn't. There was a small part of me that was very torn between wanting that like to not shave into not embrace, like big racer in that kind of thing. But also knowing how much better at felt like I'm not going to wear a dress that looks like an open back, if my back looks looks like how it did that kind of thing, but on top of negotiating her own. Feelings about shaving Alice had another important woman's opinion to contend with what was your mom's reaction to the first time. She realized that you were shaving your legs. She didn't like that. I shaved. Like after transition because of like patriarchal expectations for women to shave and it took her a little while to get over the fact that, like I can't be comfortable. I wasn't comfortable in my body without shaving. So it's just hilarious to me, because I think like of all the reasons to have apparently say how they don't completely agree with how you're presenting womanhood. Shaving is not the one you ever expect sounds like coming out with sort of the easy part is more. Yeah. Apart. Yeah. The trying to understand how much pain body hair gave me and that it was okay that I shave my legs was such a bigger fellow co to bigger deal than anything to do with my actual gender. Awhile back Alice decided to start hormone therapy, and basically that entails taking meds to block testosterone. And when you take estrogen that not only reduces testosterone production, but it also sparks the development of larger breasts shifting fat distribution and lighter body hair hormone therapies effects on body hair, usually start anywhere from six to twelve months in and within three years. You're basically at your new normal. So I was lucky enough that within like what? Eight to ten months. It had pretty much completely gone to like bond. So it was like my. I'm feeling that just like kind of verifying that I know what I'm talking about. Like. Yeah. Like my hair is definitely a lot less course. Then it was definitely thins out and super lightens up. But I think also it's just like even even though it's like just a little bit lighter just a little bit thinner. It just really makes a difference for not being completely overcome with, like grief and pain, just like, if I like look at my shoulder and see if there's hair there is like, oh, it's hair, a mammal as opposed to, oh, no. I'm going to like go shave off mmediately. So I think that that's been huge is really just like being more comfortable looking at my body, so comfortable. The Alyssa started experimenting again like last week, I wore address, and didn't shave my legs for like the first time in my entire life. And I was like, whoa. I did this and also like I wouldn't have done this. When I like hair was darker. So it was a big deal for me because like. I knew it was there. But I don't I have no idea if the people on the bus student was there, I don't know if the people the bus cared. That's the beauty of the bus. Put that on a t shirt. And it on the boat and where no one will notice. Are there any like last words, you would want to impart on listeners? Maybe it's about gender identity and body hair. Maybe it's just about what we talked about earlier as far as like what's left out of the, like feminist body hair conversation, just that it is important to, especially for, like, young transpeople, like finding a place with your body, where you can be happy with it and live with it is better than trying to be radical with it. And as amazing is to, like, be radical and go in the face of like negative societal pressures if you can't survive in the body you have because they're trying to do that. That's no longer radical now. It's just painful. So what does it take to be proud of your body hair, especially when it's presence feels extra taboo will next week? We're wrapping up, our mini series on how to wear body here by talking to one woman who's put up with body here, shaming from her school, a religious community and her whole country, and I go. Wow, if he can survive that could accept yourself might you've got to accept yourself because no one else is going to do that. Full, you don't miss it. Okay. All time to chime in on how we can be having more productive conversations about body hair. Join our private Facebook group to share your thoughts with us, and the rest of the unladylike community. You can also Email us Hello, unladylike dot co-, or find us an all the social media's at unladylike media, and be sure to check out our Instagram, there, you can find the beautiful illustrations that our friends at miss Gloria are making for this, how to wear body here series. So go check them out and make sure you check out our website for all of our sources and resources from this episode. Plus, you can also find our merge and sign up for newsletter where you'll get good news about women in the world every week in your inbox nuts, right? You heard it. Good news exists even about women. Find it all at unladylike dot co Abigail keel, senior, producer of unladylike, nor Richie is our associate producer, Jonah Palmer's, our story editor, Ashley standards, transcribes are tape. Our music is by Flamingo shadow. I'm meat may Cohen and Sarah Thompson mixing sound design and additional music by Casey Holford our executive producer. Chris, Ben and daisy Rosero special, thanks to Minnesota public radio. And we are your hosts Chris Konger and Carolina urban and y'all. If you can't wait until next week for more unladylike sign up for Stitcher premium every Wednesday we release a brand new pep talk tomorrow. The incredible Ashley Ford is helping us navigate class money and all of the complicated feels that come along with it. It's seriously a revelation go to Stitcher dot com slash premium and use code unladylike for a month of free listening, and make sure you're subscribed. Unladylike in Stitcher. Spotify apple podcast or wherever you like to listen and remember got a problem. Get unladylike. Let's gauge. Yes, because we have such a fantastic guest to engage with Caroline. How many times can we say engage? Are we now engaged? We're already married. Don't be ridiculous. Stitcher. Threat up is the world's largest online consignment in thrift store. They make it easy to stay on trend and on budget with up to ninety percent off top brands like reformation Nike free people in more all from the comfort of your own home. Y'all never have to pay full price again. So you can just shop guilt free with threat up all day long. Get an extra thirty percent off your first order at thread, up dot com slash unladylike. That's T. H. R. E. D U, P dot com slash unladylike for an extra thirty percent off today. Terms apply.
#78: Maternal Health Part 1: Exploring Fertility
"I decided to get pregnant because I. had sort of grown up around children and I had in university done a lot of courses on child development and I was actually primary junior school teacher. So I had always always wanted to be a mom when I I decided to get pregnant I was kind of settled in my career. United waited two hours really established and had been working for for years as a teacher. I decided to get pregnant I believe I was around twenty eight, and I, decided I would like to try to get pregnant than because I wanted to have one before I was thirty. In News we wanted to have children I want to non one of. My husband's one of three. So we both felt that we wanted finally together. So that was a difficult decision. I was twenty nine with do marriage for a year night. Think that I was ready to start a family. I didn't WanNa League it too much later on wanted more than one child possible and I recognize that from crips shifts, there's never a perfect time. So those were the factors that helped me decide to try to the pregnancy of that stage that was my first one was had my first child I was on maternity leave and I, decided it would be easy took someone maternity leave and have another baby. We wanted another chart and we didn't want big gaps between them. So. That's really what struck me to go for the second pregnancy. And then the third pregnancy were overseas. And again, I was on career bright I was having an extended leave said that felt like the right time. So the child. That's also finished my masters pretty recently my husband had a pretty jobs to financially we weren't too concerned but our ability to support a child mostly we were worried about emotionally whether or not we were able to accommodate that. Ultimately we sort of left it to fade and kind of rid ourselves of the burden of putting choose exactly when we wanted to start a family. I think for us. Honestly the most challenging thing was actually deciding whether or not. We wanted to start a family at that time. The toughest part is like committing mentally to that idea. Maternal health is a holistic healthcare journey during pregnancy childbirth and the postnatal period. Includes a continuum of scientific and medical through the psychosocial and spiritual aspects. Everyone's journey is different and experiences range widely with every mother creating a path that is meaningful and works well for them. You disservice sneak peek of the journeys of five different MOMS. You'll hear they're beautiful and powerful stories throughout this episode and the next in the two part series on maternal help I'm grace and I'm Nasr in today's seventy eight. We're cited to focus on the science behind getting pregnant. Will cover topics such as infertility treatments, psychosocial support getting pregnant and embryo genetic screening among others. And make sure you check out our second part of this maternal health series coming out on August twenty sixth, which will focus on the three trimesters of pregnancy itself and giving birth. Before we dive in, we want to share that raw talk has an ongoing Youtube livestream series. This summer called covid nineteen decoded each week interview one or two experts with a different perspective on the pandemic tomorrow afternoon, I hosted the eighth and final episode with Dr, David Naylor Discussing Covid nineteen immunity make sure you check it out at three pm so that you can ask your questions live. In case you'd rather an audio only option while also going to release the entire series as podcast episodes on September ninth as well as final wrap up discussion among the raw TACO's. Raucous proudly, supported by the University of Toronto affinity partners including MBNA TD insurance. You've T- alumni get preferred financial rates and rewards including a customized credit card in competitive insurance packages all while supporting alumni and student initiatives at ut Viz an affinity dot EU trot dot ca or click the link in our show notes to get access to exclusive deals now back to the show. So I tried to really become pregnant when I was twenty six years old and was really successful when my first child was born and I was twenty eight years old. I really think that it took me longer because I had an aunt birth control pills. We had started to panic a little bed and we were just certain starting to go to facility clinic and Lo and behold. Once we decided that we couldn't for clinic than I became pregnant. So I just took a bigger time and I really just think it's because I was on birth control had been on birth control for number eight years. The first time it was less than six months I remember it felt like maternity. and. I was a bit frustrated because. It's one of the few things in life you can't really control but looking back, it was less than six months. It was relatively fast and then second time I was quicker. And the time. Honestly can't remember it was more relaxed pace of life than we run assignments. So I don't remember filling onto so much time pressure that. Pregnancy it was a oh surprise I got pregnant about a year and a half after I got married at I knew that I. wanted to start a family at some point but wasn't exactly sure when ends at the time I wasn't using birth controls and certainly I knew that I was a possibility. There are variety of experiences of how long it takes an individual to get pregnant some on there. I try and others many years with assistance. This raises many questions around fertility. Privileged to speak with Dr Cajal. Dr Abbas, the fragility specialist in Toronto at trio fertility. She completed her obstetrics and gynecology residency as well as her in reproductive endocrinology and infertility at the University of Toronto she has been practicing fertility specialist in downtown Toronto ever since Dr begins by tying about how meaningful her work is to her and how we defined fertility or on the contrary infertility. I think it is truly an honor to be able to help people build and grow their families I. also really value my role in teaching many young women about their fertility helping some of them preserve their ability if they wish and so I'm really excited to be here today to chat all about artillery infertility. I think that in any discussion on infertility, it's to sort. Of Start with the basics. So let's chat a little bit about what is fragility and that may lead us to what infertility is. So particularly is the natural ability to conceive and produce children infertility. On the other hand we generally define as trying to conceive for at least one year without success and in the case of women who were thirty five or older, we say. With no success. There are some really important facts, stats that I think everyone should consider as their foundation. So women are generally most for tile in their twenties and Ben Fragility starts to decline in their thirties more rapidly after the age of thirty five, and after the age of forty ladies smart significantly compromised leading to lower pregnancy rates higher miscarriage rates in Canada and about one in six couples are going to deal with infertility. An overall about one in four pregnancies are going to end in miscarriage when discussing infertility I think it's really important to be aware that infertility effects both women and. So. Female factor infertility makes up about thirty percent of cases. Male factor infertility makes up about thirty percent of cases and about twenty thirty percent cases can be attributed to a combination of male and female infertility, and that leaves about ten to twenty percent of infertility that's considered unexplained. As. Dr Labral displayed fertility is complex and there's a lot to think about sometimes vulnerable or busy times in our lives. We ask Dr Labral when we might WanNa start thinking about our own fertility and when seeking expertise from a fertility specialist is a good idea. So I think that this related depends on whether this individual is trying to conceive warned not trying to conceive. So I'll sorta talking about each of those separately. So if a woman is trying to conceive. I would say that after one year trying to conceive without success or even six months if she's over the age of thirty five, she should get her. PORTABILITY specialists however, if she has issues with ovulation. Regular cycles and she's trying to conceive I've actually say she shouldn't wait those six months a year. She should actually get medical advice right away because this is something that we can help treat right away and actually allow her to try by helping ovulate. The other reasons in a woman trying to conceive that I would think to see a portability specialist. A little bit sooner is if she notices a sudden change in her menstrual cycles that persists, it's not something that she just sees for like a month or two and not stuff like total absence of re periods war. Having, surgery on her yours, and then all of a sudden having very light periods have been extremely heavy periods having a history us specific sexually transmitted diseases. So honoree on committee specifically can actually affect the floppy and choose if you had a history of the AIDS and possibly not introverted adequately it's worth getting an assessment anyone who's had a history of surgery involving their overseas may consider on assessment a little bit sooner than that one year mark. Now but women who aren't trying to conceive. I think that it's a really individual decision and like I said I, think it's based on their age how but also they're sort of short and long term goals and plans. So I would tell anybody is inert thirties who wants to put off thinking about their reproductive health to really be aware that the female age has a big impact on fertility. So I think it's important for women to educate themselves so that they can make the right decisions. Now as well as in the future without any regrets. So at the very least on his in their early to mid thirties host coning pregnancy may consider a constitutional fragility specialists because a basic workup would at least allow them to learn about their ovarian reserve or any other factors. Action Fax Machines is conceiving, and I also think based on those results that would allow them to explore what their options are to build a family either. Now in the future they may consider trying now they have. Even consider using donor slur. Day could consider freezing eggs. They may consider freezing embryos with a partner or began on her. So, there's a lot of options out there to get rolling mortgages, get the information and the education so they can make an informed decision. It's important that women and the partners are informed and educated about fertility early, even before they want to conceive because there are several factors that may lead to infertility these include medical disorders, one of which is polycystic Ovarian Syndrome or P.. O. S. AS DR role. Explains. So. Houses to coherence in drum commonly known as P. C. O.. S. is a hormonal disorder in women that leads to infrequent or irregular ovulation, and as a result, these women irregular menstrual cycles. So the diagnosis s actually requires two out of three of the following criteria. Holly cystic ovaries on ultrasound. So that means that they have many many tiny little follicles fluid sacs in their reason often looks a little bit like Pearl Necklace on ultrasound. They have what we call all ago ovulation, which is infrequent irregular ovulation and may have clinical or blood work at of high. Andrew Jans. So clinically, this may be acne or increased hair growth throughout the body and in terms of blood work they may. Have High Testosterone or D. H. E. A. S. or other injuries in the black, and this disorder affects about five to ten percent of reproductive age woman. The reason it's such a big deal for fertility is because it leads to infrequent ovulation. So this hormonal disorder causes women not obviate regularly extinct about it. If a woman isn't ovulating and releasing an regularly, there is no egg to make sperm and help her get pregnant. Other disorders that can affect female fertility are often grouped into three categories. Ovarian Causes Philippine Tuba causes or uterine causes. For the ovarian causes category delayed fertility or infertility may occur if there is ovarian dysfunction or diminished ovarian reserve of eggs, this can be related to advanced age family history of early menopause drugs such as chemotherapy or genetic conditions to which are fragile x Syndrome or Turner Syndrome. Fragile XM can occur in males and females and occurs when there are changes in the FM. Are One gene that prevent a protein involved in creating connections between cells from being produced and often manifest with developmental or social delay. tertre syndrome only affects females and results when one of the x chromosomes is missing or partially missing. It can manifest in a variety of ways including short stature, cardiac defects, and importantly failure ovarian development for the tubal causes category infertility due to infections such as pelvic inflammatory disease or sexually transmitted infections as well as endometriosis. And only trio says is relatively common affecting approximately seven to percent of women in Canada it is a painful disorder which tissue similar to the tissue that lines your uterus the enemy tram actually grows outside of the uterus on over as bowel and tissues lining your pelvis. Finally. Uterine or causes a female infertility can include structural abnormalities in the uterus. Polyps, or adhesions. It is important to remember that there are disorders that commonly affect male fertility as well. They can be categorized as pre testicular to stick your or Pasta stickler. For the pre-test testicular category, male infertility may be due to an endocrine disorder such as diabetes or Hypothyroidism the misuse of Andrew Johns otherwise known steroids or erectile dysfunction for a variety of reasons. For the testicular category, maybe due to infectious such as EPA MIDAS, which is an infection of tube in the back of the test goals that carry sperm or sexually transmitted diseases. It can also be related to genetic causes such as Shelter Syndrome, which results for males being born with an extra x chromosome. While the presentation can vary is often diagnosed in adulthood most men with this syndrome H- adversely affected testicular growth causing reduce levels of testosterone. Finally, for the posted category, the male may have a congenital or acquired blockage in the difference due to infectious genetic or traumatic causes. Importantly, it's not only medical disorders that can affect fertility lifestyle factors also play a part. There are certain lifestyle factors that have been suggested and shown to impact equality. So smoking is a good example. There are studies showing female smokers may go through menopause five to six years earlier than nonsmokers that has some suggestion that lifestyle choices such as smoking may impact a quality and there's probably many more of these that we don't necessarily know about such as excessive alcohol and what impact on many on a quality term but smoking's the best example all that eastern have some evidence on. Dr Paul spoke about studies showing genetic component to one a woman goes through menopause their mother or other went through it late, they may also go through it earlier late but this is just one component and not all women follow these patterns. Some lifestyle factors may delay getting pregnant but not caused direct infertility such as being on birth control methods for long periods of time and waiting some time for fragility to return. With so many complex factors leading to infertility. If someone has concerns about infertility, they can speak to their primary care provider, and then we'll usually get a referral to a clinic such a doctor rolls. We ask Dr Bull. What is like for somebody coming in for consultation clinic for the first time. I think when you go to fragility specialist, your starting point is a consultation. So that's a visit with the doctor, and that's when I take the detailed medical history from the patient as Wallace from the partner. If there is one I want to look for factors in their medical and their surgical history or their lifestyle that. Impacts their fertility. So these are things like the pregnancy history if they have won their menstrual history, important things like are there cycles regular to the pain with your periods? I WANNA know about history of any sexually transmitted infections surgical histories of a big one? Have they ever had surgery in the abdomen or pelvis or directly in the nearest I also ask a lot about other. Medical issues in medications, some affects fertility, but it's also a time to sort of prepare for pregnancy plan for pregnancy and talk about the impact, those medical issues or medications on pregnancy. At that visit, we will generally plan investigations or what I call their workup. So for a woman, a basic fertility investigation is gonNA include testing her uterus flow in tubes as well as your ovaries for. Women's Uetersen into you can either do this through an ultrasound test. Worn extra tests of the ultrasound test is specialized ultrasound called Asana histogram, and it's where we inject a small amount to saline solution into the year s so that we can look inside the cavity and make sure that it looks good. We want to make sure that there's nothing in there that could potentially decrease their chance of implanting pregnancy or increased risk of miscarriage. At the scene time, we'd follow this fluid through the past of the Philippian tubes and assess whether their Philippian tubes look over not the. Task is fairly similar were assessing the cabin in the Philippian tubes. But now we're using an x ray and instead of sealing solution releasing a little bit of a contrast either Jackson. When we're testing women's overseas, it involves testing her ed quantity, which is also known as her ovarian reserve. So we know that a woman's a quality and her quantity are both Klein as she ages. Unfortunately, at the present time, we don't have a specific test to predict equality. So egg qualities largely correlated with a women's each. And as I mentioned before, that release starts to become a factor afternoon thirties. There's also no single test that's going to tell us exactly how many eggs she has an how long she has to get pregnant before her tilleke significantly affected but we do have a few tests that help us reflect a quantity and thus give us a sense of how over Zirkin respond to fragility. We call Ovarian Reserve And the include a d three F H level. So that's a hormone that we measure in the blood. It's Day three Antra follicle count. So that's an ultrasound assessment of her own. What are we count the number of follicles or fluid sacs within the over east that holds the eggs and then the last hasn't h malaria level. So this is another hormone that we measure apply, and we use these three results together to get a sense of what a woman's ovarian reserve. This is it average? Is it a average or below average, and from there we can predict how she can respond to creativity medication in what is prognosis fertility treatment. When we're assessing a male patient they're testing would involve a semen analysis. So that's essentially a sperm test where we look at the concentration of the sperm, the Motilal or movement of the sperm, Anamur follow which looking at the size and shape of this firm based on all of these results are workup for the female partner, a workup for the meal partner. If there happens to be one, we would then be able to discuss all the different treatment options that make sense for either into the joy of the couple and their prognosis from each of these, and then make treatment plan that makes sense for them. Of, these testing procedures new medical terminology and difficult decisions can be exhausting for individuals and couples. There is much more to the journey than the medical and scientific side. This is why we're excited to introduce our second guest Amirah Posner to the episode. Amir has both a bachelor and master's degree in social work from the University of Manitoba, and is now a therapist with a private practice focused on infertility in Toronto. She also has a specialized certificate in hypnotherapy so that she can use hypnosis as a therapeutic technique. Here's Amir Story and starting her practice to help individuals and couples who are struggling with infertility. My journey was ten years ago actually today my twins, it's their tenth birthday today. So ten years ago my husband and I we went through secondary infertility. So we had conceived our daughter effortlessly and we were trying for number two and it wasn't working as well as it did and we went to the fertility clinic eventually in few months down the road, we were told that IVF was our best option. So we proceeded and we did IVF and we were successful and I. Ended up conceiving twins and our story ended happily enjoy asleep but it was one of the most difficult times in my life. I remember feeling like something that once worked. So well, what happens and I felt like something was wrong with me I was defective and I slowly began to isolate myself from my friends just feeling all these different types of emotions and I was a social worker at the time I had my masters in social work and I was a counselor and. I just I knew that if I, get through this that this is going to be my area that I'm going to help others also get through it. So when the twins turn to I started running this very grassroots support group out of my parents condominium amenity room and I called it the mind body fertility group and it was very wonderful. I had another Collie who joined me and we had seven women and I could just see how beneficial it was to bring these. Women together to talk about a common experience and struggle and share all the different emotions and I also thought I wanted to provide tools to help them cope better. So that's where the mind body came into, and we covered a number of different coping techniques, mindfulness to cognitive restructuring to fertility yoga, and so from my parents condominium amenity room a connected with one of the social workers at one of the local hospitals and I met with her and we started running the group. And I continue to run the group to the states eight years later, and I also run a program online which is geared to the same content, but it can meet women all over the world. Amira's lived experience is invaluable to the work she offers and encourages today Amir highlights the importance of others with lived experience coming together to talk and work through the emotional or mental side of the maternal health journey. I don't remember there being a lot of emotional support out there. I didn't access any at the time. So I felt like it was a needed service and I also felt like the coping techniques were essential because when I was going through it, I didn't know what was happening. I just was in a bubble of I want to get pregnant and do anything when I was going. Through it I remember like from my past past, I had done the mindfulness and so I sort of brought that back into my journey and I found it to be really helpful and I thought wow, this is so healing and so like changing of the mindset through the struggle, and that's one of the big tools that I like to use in my practice and in my grew. Similar to Dr, rule we asked Moore to describe step by step. What might be like coming to her for therapy for the first time. Yes. So everyone's different and you know I often find with this population someone will come and make an appointment and come in. There's anxiety is so heightened that. I really need to have them kind of settled down and come to a place of calm before we can actually talk and I can help them try to see things differently. So using some of the techniques to help them calm their system and then teaching it to them. So they can do it for themselves, and then once they're in a more balanced state, we can start talking about some of the motions that are coming up and normalize ation because it's such a private topic people don't talk about it. So there's a lot of shame associated with it. So help bean, the women understand that they're not alone and that it's a very common. Phenomena that we experienced during a certain age group and helping them broaden their perspective so they can have more flexible thinking and. A better relationship with themselves and the people around them and their struggle. So my support group, it runs for six weeks. It's very structured and each week we focus on a different technique. When I see some one on one, it could vary. So sometimes, I'll do that content one on one with them or sometimes it's a couple that needs support just in their communication. Or sometimes it's an individual or a couple who are using donor conception. In those cases, I would meet with them and talk to them about the implications involved in using donor sperm or egg donor or surrogacy. So families are built many different ways and it's just fascinating. Both our guests have similarly spoken about their approach to care intriguing the individual or couple that is in the most meaningful and useful way to them because everyone's different we us Dr Labral what is the best thing a patient can do before coming to a consult in which she would expect in a patient coming to an infertility clinic for the first time. I don't have any real expectations for my patients a really do want them to come in with an open mind I want them to come in and share as much of their medical history with me. As possible if I'm seeing somebody passively a second opinion, I want them to share the previous treatment history but also their experience with me so that we can develop. A relationship. I can make them comfortable are releasing just being really open minded I want a patient. He'll assertive ready to share their history of me equally were Eddie to learn from me and go on this journey together in terms of doing a complete work instead of investigations and learning from that, and then together making a treatment plan that works for them and sense them. Switching gears a little bit. Let's return to some of the main medically based infertility treatments. Doctor will explain that there was not one that was the most common, but that it really depends on the individual or the couple. So when I think fertility treatment for someone who wants to conceive I, like to break it down into sort of three main pass. The first treatment which actually isn't really considered assisted reproductive technology or air T as we call it, it involves a woman taking some medication at the start of her menstrual cycle to try and develop more than one mature Guinness. Cycle. So as we naturally mature one egg per cycle and Oscillate we wanNA make a few extra to increase the chance of an egg and sperm meeting. We can then combine us with intercourse that's trained right around ovulation to help a pregnancy and we call this controlled ovarian hyperstimulation in a woman who actually doesn't ovulate regularly, we can still use the same medication and the same process. But now what we WANNA do was help her develop even just a single mature egg. We call this ovulation induction and it also is combined with Time Jansher course to help her get pregnant. A second pass, which is actually an assisted reproductive technique is called injury aren't insemination or UI. So once a woman is ovulating either one egg if she's just having an actual cycle on more than one egg if she did controlled Ovarian hyperstimulation, we've been washed the sperm process it and place it inside her uterus. So bypassing the cervix and the cervical mucus and we're putting the sperm one step closer to the egg or eggs in order to help purchase pregnancy. and. Then the last third treatment option is in vitro fertilization or IVF also a type of rt says this involves a process of stimulating a woman's ovaries with fertility medications usually, but not always injectables. So the limit all's where we're trying to grow and mature never of eggs over at ten to fourteen day period of time we then actually remove these eggs from the body through an egg retrieval procedure, which is actually an ultrasound procedure where we're draining fluid from Neal's Looking for the little microscopic eggs in the lab and then taking those eggs for wising them with sperm in lab in order to make embryos, and then we're growing these embryos in our labs five to six days I, and then transferring them into uterus where hopefully they're gonna implant and give pregnancy. Amirah talked to us about her journey with reproductive assistance. So it was kind of an organic process because when we started at the fertility clinic, they were quite hopeful because we had conceived our daughter naturally oftentimes when a couple starts at a clinic they. Doing all the fragility tests and sometimes that takes a bit of time. So during that time, we started other less intrusive treatment they're called in uterine insemination 's otherwise referred to as I you. I we tried that three times, but we were also dealing with male factor. So that was a problem and none of them were successful. So then we were told that this was our next best option I just was like, okay let's do it. Amirah told how important it was to have her husband included in the process. This is a large reason why her practice today offers to work with couples together to show how they can communicate better to help one another feel safe and supported. She mentioned that sometimes this journey can really help strengthening a relationship although other times she seen it go the other way. Amongst infertility options there also choices regarding genetic screening and freezing eggs before they are transferred back inside a woman. Two big topics that we can touch on. So the first one given that were already talking about I the F. as individuals who want to screen for genetic conditions. So traditionally, if a woman to get pregnant naturally, she could do prenatal screening once. This involves clever in ultrasound in the first trimester and possibly blood work again in the second trimester to screen for some common chromosomal abnormalities, something like down syndrome. But when we are doing IVF, we can actually do genetic screening on the embryos before even transferring them and achieving a pregnancy and we call this preimplantation genetic testing were peachy t and there's actually two arms to this. So PG T is where we're actually testing the EMEALS to see if they have the correct number of chromosomes forty six or forty, six x y, and then only transfer the embryos with a normal chromosomal makeup into the. US. The. Other kind is something called Pichichi 'em, and that's where we are actually testing the embryos for a specific genetic condition that is caused by a single gene. We then only transfer the unaffected embryos into this year's so just elaborating on the process of your life. What we do in these scenarios is we would grow the embryos. So firm fertilized egg grew the embryos, all the way today five or six in. Now, we would biopsy a few cells from each embryo. Freezing the embryos and then test those cells to see what the genetic. So in the case of PG t were seeing, does it have a normal chromosomal makeup or in the case of Peachy TM? Does it have this single gene disorder that we're trying to screen for and then we would put back the unaffected embryos in a subsequent cycle. So in later psycho, he would take those frozen embryos saw them in the back the unaffected. Embryos. Next we spoke to Dr Apple about why patients might wanNA freeze their eggs. Okay. So I think there are two big reasons why patients would want to freeze the REX. So the first is egg freezing for social reasons. So these are patients you WanNa have a family, but maybe they haven't found the right partner to do this way and they want to preserve their fertility keep their options open for starting a family sometime in the future I'm the second option is egg freezing for medical reasons. So these are patients that are actually at risk of losing their fertility do a medical issue something like undergoing chemotherapy or having surgery on your ovaries, and they want to freeze their eggs for sometimes embryos before the facility is negatively impacted by their medical concern. For those that are thinking about egg freezing particularly for social reasons, you ideally want to think about freezing your ex when you're younger because as I mentioned before a quality in a quantity or to decrease with H. We heard that reasons for egg freezing, really very on the individual or the couple fracturing their age and what they're short and long term goals are one would be a good time for women to start thinking about freezing eggs. So I actually think it makes sense for women in their early thirties to think about egg freezing possibly even their late twenties depending on their social situation. I don't think that every woman in her twenties necessarily needs to think about freezing rags it may be a bit premature but think that in her early thirties perhaps late twenties, you're probably balancing the benefits of better equality with the cost of the procedure any possible risks that comes with doing any medical procedure So somebody who is you know late twenties just about thirty starting medical school knows she's going to be in school a long time currently single. Yes. Definitely. Something that she may want to consider and obviously the younger you to edge ideally the better quality eggs were freezing. So it's to her benefit. You can freeze their eggs or embryos. What is the difference Oh and which one is a better option. So I know people will have different opinions on this but I can give you have partner with whom you know you want to build a family with it's just not right now I often consider freezing embryos over eggs. The reason I say that is because we have been doing I've es an embryo freezing for very long time and were very good at and embryos freeze and thaw. Very Wow. Aims are a little bit different than embryos filled with a lot of water and as a result, they don't freeze thaw as well. Now, that being said, technology has changed quite a bit in the last ten years or so we used to use a process called slow freezing and that resulted in a loss of a lot of eggs. When we saw, we now use a process called vitrification essentially, it's flash freezing and the eggs actually survive the freeze and thaw quite well. But that being said, I still think that freezing embryos low bit better the success retire you also sort of know what you have at the end of the day. When you freeze eggs, you don't actually know what you're going to at the end of the process. When you come to use them with to the eggs fertilized with sperm and then grow them. So you may start with ten eggs, but we may only have two or three embryos at the end of the day. Whereas if you did the process of an embryo freezing, you would know how many you have frozen at the end of the day you have to Israel's or do you have four or five? So I guess my short answer is. I would. Push for a freezing in a patient. He was sure of her partner and who she wants to freeze embryos. But I still think that egg freezing is quite good. So it got easier option I feel quicker than it. Had A miscarriage, my second child it was very difficult. At the time because I really wanted the baby. I was really upset about it and because I've been successful look my first two children being very healthy when they were born just never crossed my mind I would lose a child. This difficult but then. When I look back on it now, I wouldn't actually have the third child that I actually have because. That I lost would have been born with time couldn't have conceived the third child that I was successful web. So I'm grateful that I have not child. And I'm sad that I lost that baby also very excited that I have no child that I had. I had a lot of nausea with all three of my children early on in the pregnancy wasn't in the morning it was all the time. And nothing seems to solve the meeting. So I h rather law in the first trimester pregnancies and the pregnancies progressed I felt uncomfortable mice, people do I did have a lot of indigestion acid reflux. So I took to taking a little bottle of milk of magnesium. Ram. With me and my handbag went and swinging after every meal to try and stop me indigestion from happening. But no, the relatively minor things. In the beginning of my pregnancy, I was very nauseous and I had heightened smelled the not in a good way. Because everything. Made me very nauseous and A difficult time eating certain things. So I was limited in my food intake pretty much I lived on crackers and very bland and. I mean with my first pregnancy things went really well, I was very physically fit other than the nausea and whatnot it was pretty much a normal pregnancy. Unfortunately with my second pregnancy. That was not the case I. had a cyst, the size of a grapefruit. Growing along with the baby, which made it very, very challenging. I wasn't bedridden because I had a two year old. But at the same time, I was very limited in the things that I could do. I could not pick up my firstborn. Because that might induce Labor though we did a lot of activities that required things like walks to the park and lots of puzzles and lots of reading and lots of things that we can do together. That did not require too much physical activity. Had people coming in to take my son to the park and do those physical things that I couldn't do them and I would join alone but I would do the walking there and back and all the playing in the signed activities as opposed to the monkey bars and everything else. Is, pretty. Fortunate when I got pregnant, I really didn't have any like morning sickness or merely typical physically I felt really good I was able to see a doctor fairly soon after I took a urine pregnancy us yet all move fairly quickly and I really didn't facing challenges at that time. It was pretty seamless. It was really a positive experience. Is these clips show infertility is just one of the challenges that women face on their maternal health journey. Indeed, most commonly Dr Apple sees individuals and couples with infertility, but her responsibility is much more diverse than that. She explains I also see patients with recurrent pregnancy loss. So women who have had a number of miscarriage is often two or three or more needed. Necessity looks for causes. I also don't see women, men and gender diverse individuals and couples who aren't necessarily infer tile, but they need access to eggs or sperm or station all surrogacy or than you want to preserve their fertility. And as mentioned, I actually see a number of women who are not yet wanting to start their family, but they're interested in Chile assessment and interested in pursuing egg freezing though I would say that sort of sums up all the different reasons why someone may need expertise? Amira shared a bit more about how mindfulness commute great tool to stay present in the sometimes difficult journey to having a child. Mindfulness is really having harnessing our attention more into the present moment and often times we are living in the past reiterating things that have already happened or were thinking about the future and trying to plan accordingly and. A lot of times. When we're going through this journey, we are living in a lot of anticipation and were not present. So mindfulness is a tool that we can use to bring us back to ourselves instead of thinking about our problems and trying to problem, solve and figure things out let that go and just be in the moment wherever we are and it has many different effects on your emotional state to your physiological state and it's a practice. It's not something that can just. Be Mindful, and then you're mindful like a muscle and so just harnessing your attention in the present and working with your thoughts in a different way can be really empowering. Then that's key and I know that sounds really easy but it's actually really hard. We ask Dr Role with the biggest misconceptions field are she told us that age matters not to the point that we need to panic in our twenties but that we need to be well informed. That aged does not matter and vs can fix opportunity issues. I want to correct that age does matter all watch for one. So, even if you look and feel Yang and feel your best unfortunately that doesn't apply to reality and your ovaries because as I've said over and over again and our chat today both a quality and quantity Ju- decline as a woman ages specifically over the age of thirty five, and unfortunately, there isn't a tree to reverse. Egg freezing may help women preserve their fragility and give them options in the future, but we don't have a wait to reverse viewers aging and treatment such as ivy action come a really long way. ROIC agreed truly so many different causes of infertility improving pregnancy rates. They can't completely solve every issue every time. So for example, you can agree more and more immediate. We're seeing that women are having babies well into their forties maybe even early fifties we see celebrities all the. Time and I think people are really led to believe that age didn't matter and that idea help them. But the real answer actually is that using an egg donor to overcome the impact of each quality was there is just not necessarily talked about in the same way. So I think as a result people think that isn't such a factor that will help the regardless of their age. I'm not here to say that IBM is great in that it can't help us just cancelled and. Amir that there is need for education and awareness yes. So in. He doesn't discriminate and can hit you as early as in your twenties women as young as twenty five may be diagnosed with premature ovarian failure and need to pursue treatment were sometimes there's male factor and there's been impact to the sperm and they need to do IBF because of that. So, not always just an older patient. So now the government offers. A funded IBM treatment, which is an amazing incentive. program. So the cutoff age for that is the end of forty three. oftentimes, women aren't talking about the emotional side of the infertility journeys. We asked Amira if people seem to be talking about this more. Yeah I definitely think. So just with social media and people sharing more of their personal experiences and communities getting together for different causes and I guess it's becoming more normalized because we have more ways of it be normalized and just being out there. So I feel like now they're there is more emotional support for people to access and. There's more physical support as well like through naturopathic treatment and acupuncture and Ricky and other healing modalities. Encompassing the whole person, the mind body spirit. Finally doctor told us how she sees the future fertility in her field. The peony of this field of medicine is that it is growing in changing all the time. For example, at this time, as I told you, we don't really have a great way to test a quality but my hope is that we're going to have this technology really soon and I think it will give physicians and patients, really, valuable information. The same goes for testing uterus for issues with implentation, we do have some tests but. Still. Fairly new and there is no one test that is the standard of care. But as research continues I, think it's going to lead to better and better technology and testing. So it's hard to say where I see a future fertility specifically I guess I just see it changing as rapidly as has in the last twenty years. Excitingly Dr. Role has a podcast of our own coming out that she wants to share. Soon, anyone has any questions or wants more information feel free to follow me on Instagram at Cogil. MD and my podcast is actually coming out soon. And it's called fertility. Docs Talk. Similarly Amir has some plans for the future of her own practice and as always happy to have a conversation. I'd like to think eventually expand my groups and create them retreats in the summer for bigger groups of people to get together and heal and nurture themselves through their journey but I'm very happy doing what I do. You can check out W. Dot healing infertility dossier tiller more about Amir services where she works her groups and her online programs. She's happy for you to send her an email and chat more. Trusting care are the cornerstones of our guests approaches with their patients along with the understanding that pregnancy is a vulnerable, an intimate experience for many and such. It is important for the patient and provider to be on this journey together. Both guest discussed the need for a multidisciplinary approach to care referring to one another for medical psychosocial or emotional support. Some fertility clinics have both specialists right in house. Mayor has some words for listeners who may be facing their own challenges or know someone who is. Yeah. So I think it's a journey and there's always the concept of impermanent sinned won't always be like this and it's hard to really grasp that when you're in aunt. But just to know that you're not alone in that, there are tools in there are people to talk to its doesn't need to be so devastating to go through their support out there and there's ways to get through it. You can't get around it unfortunately to get to the other side, you have to go through it, and sometimes you turn out to be a different person than you were when the journey started. I can't imagine my life about children because I want children so badly, and they mean so much to me I always tell my son that the day that he is going my first son, it was the best day of my life. Changed me. In. So many ways in terms of becoming a mother was kind of everything that I imagined it would be and so much better. So I. Think. If you're thinking about having babies is such a wonderful experience and then you go from the first baby to the second baby. Is like me will expand your circle of love. You think that how could you possibly lop another baby as much you love your first baby in somehow you heard this opens in the circuits bigger and bigger and bigger, and you know the circle of love expands and it goes up for each child. You know if you're thinking about getting pregnant, it is absolutely wonderful. Children are really the best thing I could that ever happened to me in my life. I, you know that's a tough one. I think one of the things I learnt mice from having three babies is all the buffs I also discovered the all my friends having. All of our experiences What none is that what's right for woman isn't necessarily right for another and the worse thing is for women to feel she's done it roll off, feel guilty or to feel failure, and so I'm very cautious. Now an argument vice because I recognized every woman is different and every situation is different. If a woman came to have a home garth and it supported in the country infrastructure that she has the night, say go for it but equally don't feel under pressure on recognized that even the best laid plans of mice and men as they say that maybe you're kind of new may have to change if there are complications. Most important thing to me during my pregnancy was information I think the prenatal classes I attended were so informative in terms of advice I think a lot of people get unsolicited advice when they're pregnant you know it's not always super positive but I would say if you can attend a create office do so especially when it's facilitated by reputable hospital like I think that can be super. Helpful. With. My son actually the funny part was I came home and realized after waking up every couple of hours that the reality of US sleeping anytime soon. But funny enough once he sorta get used to that it's not a problem anymore. You think in the beginning, how am I going to function the next day not being able to sleep and getting up every two hours to breastfeed and so on and so forth. But you do find your rhythm and you do find your way and it's all okay in the end. With my second child. Funny enough. It wasn't an issue I think as much because there was no unknown. I had sort of been through the unknowns with the first child. So the second transparency, especially vis-a-vis feeding and whatnot, and the not sleeping wasn't so alien. We would like to take this time to give a massive. Thank you to both of our guests, Dr April, and Amira, for their insight and expertise as well as our mothers, Brenda Georgia and Bessie who have shared their own lived experiences. In short clips, we have added other fertility and maternal health resources in our show notes. One resource worth noting is Dr Jennifer Gunter. An obstetrics gynecology specialists who is a fierce for women's health and very active on twitter. She empowers women to embrace their health and not be afraid to have hard conversations. She also has her own show called. John's blaming a book called the Vagina Bobble that you may WANNA check out. Catches next time for part two of our maternal health episode where we build on this discussion to talk about pregnancy and delivery. Be sure to also watch our covid nineteen two coded Youtube livestream series. Thank you may Ron who is our photographer Helen Audio, engineer and Jillian Nasr Frank Esther cat. who were content creators interviewed our guests I was our executive producer. and. Until next time keep it raw. Raw Talk podcast a student presentation of the Institute of Medical Science in the Faculty of Medicine at the University of Toronto. The opinions expressed on the show are not necessarily those of the mess the Faculty of Medicine or the University to learn more about the show, visit our website dot com, and stays today by following us on Twitter Instagram facebook at rock talk podcast support the show by using the affiliate link on our website when you shop on Amazon. Also. Don't forget to subscribe on Itunes spotify or wherever you listen to podcasts and rate aside stars until next time keep it raw.
Ep 17: 7 Years Sober To 7 Figure Nutrition Business w/ Brad Jensen
"Dan I had a client asking. How do you stay motivated all the time and I said what gives you impression on mobile? She said well this day in and day out. I said it's my reality. It's how motive is just what I do when I shower against my reality. It's not motivation. Motivation is super transient by nature. It will come. They'll go the days days. I actually feel motivated in the gym. I'm like yes like school because I know with every day is not like that and so I think there's a misconception and when you start to do gain in doubt it just becomes a reality as we do. Welcome to the super night on your host frank rates and this is the only podcasts in the world dedicated to helping men break free from the shackles of addiction. Through the power of faith and fitness. It is our goal with every episode. Help you take control and rebuild your body mind and spirit and we do so by bringing real enroll conversation with people just like aiming to find their place in this world while dealing with the everyday struggles in battles that we all face now. It is my belief that we raw agents for a specific purpose and if we can harness that belief or faith then take control of our mind and body or fitness then we can ultimately create the life that we've always dreamed about our superhuman light. I wanted to know how grateful great four I am here today. Let's get on today's show. What is going on guys is welcome back to the super human life? We are here on episode. Seventeen he can't tell by boys. I am fired up because I know that today's episode is GonNa be a life changer and honestly like I said episode seventeen in every single show guest conversation Just keeps getting better and better someone new to our guest here in a minute but let me just kind of set the tone for what you can expect out of today's podcast now as we share on quite a few are shows. You know my goal here with this episode of shared this mission with you so many times to help men break free from the shackles of addiction through the power of faith and fitness. And I do that by bringing on real guests with real stories. Real struggles goes that they've had to overcome in our having impacts in the world at a mass mass scale in our guest is no different than any of those He's known as the sober bodybuilder on instagram. His name is Brad Johnson. Now Brad is the founder and owner of key nutrition We deep into this episode on the Michigan. Behind Hi keen attrition the four pillars that he's built this nutrition coaching program on we talk about some of the incredible success that he had. I really love his perspective on when I asked asked him to look back on. Probably the biggest confident appointing nineteen. I was so incredibly just Just blown away by his response in his answer. So Oh we get into that little bit towards the end of the podcast so make sure you stick around for that now. Brad is also the host of the key nutrition. podcast some link all this stuff down below. Hello guys if you're if you're looking for some insight. You're looking for some coaching. He's he's he's got a great approach all encompassing in a holistic sil- approach utrition in training mindset accountability. That's kind of the four pillars that he's built his entire coaching program on. So those are the things that we get in towards the end of the podcast But we we really really go into detail at the beginning on Brad story now Brad like myself as somebody that got into fit is at a very young age we talk about what led him into you know really diving. Deep into fitness and bodybuilding In his early teen years we also talk about how that same motivating factor that insecurity that defaults Those feelings in doubts about himself ultimately lead him down a path for for a good portion of his early twenties and almost two to thirty of getting. Get some really dark places in Dr Times. You Know Brad Is Very Open and candid about his his struggles with drugs and alcohol and addiction and felonies crossing crossing borderlines with a car full of drugs and it's it's just incredibly Eye Opening Story Now one thing that Brad goes goes into depth and detail on in this episode that I don't think he's believed he shared on any other any other podcast is his relationship with God and he talks about speaking God in his prayer. You know from from the prison cell in it's such an incredibly inspiring inspiring story but Brad has a real story of redemption. You know it's like He he just celebrated his his his seven years sober and that that's what triggered me to reach out to him as I. I saw that he was celebrating this But it's not just so much about staying clean for seven years the fact that he's now found his mission in the world and it's through coaching. It's through is helping. And he talks about how he's had to to lean into his faith and connect with his nose creators heavenly father and like I said this he shares some stuff on this podcast that I know he has not shared anywhere else. And that's why I'm so fired up because if you guys know Brad. He followed him. I'll see he knows that. He's a great nutrition coach. He's a leader. He's a great trainer. He's a great bodybuilder. Rate family man but here he's he's a great man. Christ he's a great man man of God in in in in that with something to me that I wasn't expecting to get into because you like I do with every single episode. I always do a little bit of background research on on the gas ask in. I hadn't heard him talk in this fashion but You know he got he got hit with it and he just goes into detail just so fired up for every single one of you guys Today because I know that this podcast this episode in particular has the impact it has the ability to really change. Somebody's is out there If after dark time right now in their lives so without further Ado Gaza. I WANNA jump into this podcast but as I before I before I end this as I do with every single episode Share with you. The mission is to is to truly impact change. Change the world on a mass scale and the only way I can do that is by your continued support. So if you find value in this episode or any other episode and you have not done so yet please make sure to hit that Subscribe Button on Itunes. Whatever podcast platform? You are listening to and also if you can share the message if you can share the podcast with just one person in another thing that can help us gain more exposure. Get our get our show in front of more listeners. As if he could leave a rating and review on whatever podcast popcorn. You're out there if you're on. I tunes obviously. That's that's the number one Platform Right now. So so Joseph favor only if the only podcast is providing value to you. I'm not asking for are you know. Fake reviews fake no fake ratings But if you find value in this fits if it's really having an impact in your life you have not done so yet. Please do it since one favor over and leave a five star rating in review without further. Ado Guys I want to jump into this episode with a Sober Bodybuilder Aka Brad Johnson. Talking All Things Recovery Life Coaching coaching Mill N in his mission behind building key nutrition. Let's get on with the show guys. Brad my brother. Welcome to the super human life. Thank you man. Appreciate appreciate the opportunity. Dude I'm a I'm I'm so excited about this one because you know one thing I always do kind of prepping for these shows is is Kinda dig into the person's background and story a little a bit and you and I have so many parallels like in our backgrounds in our lives. I mean From getting into fitness at a very young age and then obviously you know some of the stuff that I really want to get into their story today but I man just just thank you for coming on here and I want you kinda tip my hat off to you. Because this conversation was sparked by post just a day you had. I think it was maybe about a month ago. Or so You celebrate something. Pretty big in your Zack corrects correct. Yeah yes Albert seven seven years clean and sober from all mind altering substances which is crazy and that was November twentieth So Sobriety Days November Twentieth Two thousand twelve and for that. I'm eternally grateful and I think it says far more about God than it does me but I'm I'm grateful. I was able to peninsula action and in working himself. Amen Brother and You know what's what's what's truly incredible about you and obviously this is where no we're GONNA get into a lot of this over the next hour so this conversation is not just the fact that you've you know you've hung around here seven years when you've had to strengthen everything to stay clean and sober but what you've actually accomplish here within the last few years with Your Business and your coaching so I really WanNa Kinda get into some of these things that as you know leads you to build this team and build this company key nutrition to a level where it is I definitely want to get into that stuff But just kind of piggyback off of that you know seven seven years sober you know. I think where we can have the most valued today for people in his. Let's take them back you know. Let's take them through This journey to recovery and and in doing that. I know that there's GonNa be a lot that we can withdraw and extract and kind of have some real guidance in in in an impact for people. So yeah man I kinda wanted to open up here today with A. Let's kind of dig into Brad. You know let's dig into his background fitness. Let's let's talk about your journey little bit so wherever you feel is a great place to start but I'm gonNA hand it off to you and You know all all kind of guide right here. We kind of set the tone here sweetman. Well thank you you brave Sam. By the way you gotTa braves add on I answer. Yeah I grew up I grew up here in Tampa You know in the ninety nineties kid did and this was prior to the Tampa Bay rays so the only team that we really had to support was the brave so yeah it was like through the nineties in you know. Fourteen years consecutive live winning winning the pennant and everything that was my alma goes through team in. Nice me too. Yeah I mean I lived in Utah Ride but big braves fan and so I- naturally they became a braves fan because I wanted to be like him and they were on. TBS Every day. So I got every single game even though I lived in Utah so I was a huge braves fan. Yeah it was that that the T. B. S.. It was like always seven. Oh five hours. Remember this it's so weird because everything always started at like oh five and online at Mike. Why is it five minutes later? They're you're like they're only eight hours away from me like are they in a different time zone. I didn't understand it when I was a kid. Five five for me. I remember that so so yeah that was done. How's my passionate baseball growing up so youtube? You're you're you're ballplayer now. I didn't play baseball. I just loved it loved watching it and it's kind of funny that's always been my Mo- was I was is really big into sports and but never really playing them I still am a huge sports fanatic in because some disruption in my life like action legitimately people laughing like reevaluating some things for twenty twenty because I get really really hung up my teams. Don't win in. It's just this. This complete utter utter denial of powerlessness. I'm just like no I'm just gonNA stay mad about. They'd like the one thing I have not conquered so With this was actually something. Just just real. Oh quick. I don't WANNA I don't WanNA enter interject too much but this has actually been something that was really life changing for me. This year I was I was a sports addict. I was the guy seven days a week baseball baseball. MLB Network was on like it was on dern. Work is in the background. It was on at night sleeping with a game just constantly run it like my girlfriend issue like how can you just watch watched for center over and over and over and over again. It's like the same thing But this year like one thing we did is we. We cancelled cables. I don't even have access to like turn the sports on anymore anymore. I can like this is the first year. I haven't sat down and probably the last six or seven years. I haven't sat down on Sunday for like six hours on the couch just to watch. Nfl Red Zone not completely removed. It's incredible like the productivity increase just by kind of removing a sports. From from my life I had is often. That's incredible. Yeah so yeah. I don't know if I'm ready anxiety. But maybe that's why I need to address it right so usually right. I think I think we'll probably figure that out here in your story story little bit. It's like we're like we're the anxiety is is kind of like where you kinda gotta go through. Sometimes I'll one hundred percent agree man so yeah taking me back a little bit. I grew up I grew up in a good family Good religious family They were of the LDS faith So and was young as five kids. I I everything provided for me that I needed. We weren't we weren't rich but we definitely weren't poor. Uh My all the love in the world It wasn't supposed to happen to me. I was. They'll be like you look at my family. It wasn't my mom you know wasn't a crackhead and my daddy wasn't around like I just didn't have that story like oh they were really loving to me. Really good the parents. I think it's always important. I try to frame that because I think that so often people. They really was not supposed to happen to me like they did everything they could. I was raised. They didn't my brothers didn't drink wasn't around alcohol or what you know. It wasn't in my house I didn't I drink from my mom's liquor cabinet so despite all of that you know addiction does doesn't care doesn't discriminate. Whether you're rich poor white good family bad family like it was just in my DNA so an was chubby. Kid the awkward phase between ten and thirteen and my first obsession was food. And I I didn't even make this connection. I swear to God until just barely on on different podcast when I was telling my story that that's when it really started i. You know obsessively eight macaroni and cheese with hotdogs in it. And they played Sega Genesis World series. And I just ate an eight and I remember like my mom would be like. Don't you get full. You eat a lot so it started there. And of course when you're having to puberty liberty yet and and I'm eating all day and I'm I'm not into sports playing them but I'm into watching them and playing them on video games and so gained a bunch of weight. Obviously and I was picked on and was teased a little and it was hard and it was hard as a kid and I think it's still hard that age is just so awkward. Some people are hitting puberty sooner than others and it's just like a it's it's it's brutal man like as as as you're telling us on Mike I'm resonating so much How how what are you by the way I'll be thirty five next month. Okay so you and fire only about a year a year apart so yeah the macaroni and cheese and take a genesis that was like That was that was afternoons after school for me like in elementary school like I could. I can come home. Empty the entire box into a big bowl. Just throw some water and then the powder cheese on a lunch man so the I definitely get it to with like not Not Having the ideal Zeke or you know what I mean like you. Don't think about this as a kid. I was the same thing you know. Just do think The nutrition at I was putting into my body not like I. I got a little Husky. I've talked about this with somebody else on on the show. It's like shopping in Husky section in JC Penney's like you're kind of like looking for other kids in your school like you don't want them to see a you like under the big sign because they know that's for the little heavier kids so dealt dealt all this same kind of like insecurity feeling sue and I know that's what you would My passion mm for fitness so Yeah no I didn't I didn't mean to cut you there but I know you great man. I love album just conversation so excuse me I am and I got picked on right and we all know that the only man it socks. You're not you're not emotionally mature by any means and to identify like Oh mom. I think I'm having anxiety I don't like being picked on my self worth as I'm very good because you didn't know how to express any of that so I kept it all inside and and Buy I started getting this paralyzing. Fear even go to school and I got picked on and thrown in the snow and they whitewashed me whatever right in my head I felt like I got jumped by fifty guys was brutally be and they said if you ever come back to school. I'm GONNA kill you. That's how I felt when I went home and I told my mom never going back to that school and she said you're in sixth grade that you have to go when I saw him not going. So my mom being a great codependent in enabler ship me out to California to live with her sister my aunt in northern California in the bay area and when I got there her I went to school there and I hated it too. So I home schooled the rest of six grand and that's when got even worse as far as my eating and so I got I came back to Utah about a year later and It was definitely still being picked on. I was my friends were they. Were my friends this time. Instead of just like random people school by definitely was made fun of and I didn't like it and you know I'll never forget one day I just opposite the bookstore with my mom. It would be so nice if the wasn't it was nowadays. I've just hop on Google but that's barely when. AOL came out. You use a CD and they timed you. They do pay per time like how much time you spent your. Yeah it was so new then and and then somebody picks up the phone and it kicks off the Internet and you're like screaming from the other room like come on. I'm on the Internet like it would be so slow. It's funny our patients level. Now it's running a millisecond slow. You know I it was it was It was tough and I I was at the was at the bookstore. Komo was buying a book and I went over in the section in I remember seeing. These magazines was flex magazines muscle and fitness. Nothing about it made sense why I was so attracted to these these magazines and they picked him up because I have never lifted away. I didn't I didn't I was fourteen years old. Fifteen may be and I was fascinated. I picked that up and I said how that guy one day and and I just started reading and it was the first in my entire life that I'd ever been passionate about like it was like I couldn't get enough my mom's like you don't WanNa leave Barnes and noble like come on like so. I started taking my bike after school there every day and I would just read and I stayed for about three or four hours. Read and read and picked up the encyclopedia bodybuilding. Only by Arnold. I was a Saab Ridge to to very poor student at best a just an. It's not because I was dumb because it just an interest me at all and as is any good addict alcoholic like I just was like mom I gonNa do it then so barely pass school. But I found this love for fitness and I started applying. The was applying with the magazines told me in. I also a growth spurt subsequently and I lost a lot of weight but I looked good and but I remember then. I get teased for being too skinny and I was like. I can't win so in between my sophomore born junior year I really really picked up into weight. Training and really got into a little more of it was still very thrown out their knowledge base as we taking tuna fish and rice to school when I was eating in the hallways and but my body changed and along with that people viewed differently and it was. It was a good feeling it was it. Would I noticed I had arrived. I felt like I was there am yeah I I remember my my big transformation actually came a little they later than yours. I dabbled in a little bit of weightlifting during high school because of sports that I was playing like we had team lifts and everything and but all season protocols but it was like post high school win. I kind of like I moved away from the town where I was going to school and kind of disappear from six months In literally was like two days in the gym like I mean I worked out at twenty four hour. Our Gold's gym back there and it was like at two. Am like with the hardest core bodybuilders in the world insight. Six months I literally just became a whole different person In in yeah I remember that feeling feeling kind of like the first the first physical transformation do you remember Going back kind of like to to probably are kind of like early Ish maybe eleven twelve teenage years. There's like the ESPN workout shows on like Saturday morning. Elliot Oh yeah I was so hesitant. I never watched cartoons like anything on Saturday mornings until I found like the workout shows does and I'd sit there with like a giant Pol cereal at like eleven years old and I just would watch these Jack dudes lip like I wasn't taking the workouts and then going to do them I was just fascinated hit by the physiques in the training thing and then years later I actually like put a lot of that stuff into practice so I remember absolutely do Yeah and I'll watch the strongman competitions and I was like how that's really cool and carry an atlas down but yeah I wasn't I wasn't going out and applying it So I found this in what's interesting. There's always tell people the Wisconsin this double edged sword because I started evaluation and attention But it kind of almost insinuated this part that I have to be a certain way to fit in in so but you know so as a as a seventeen year old I would take it right during that time too. I also realized how bad alcohol was for my body and through that process I mean I was Geeky out. I got smarter and Smarter Smarter. I mean still looking back. I was pretty stupid but I found out how bad alcohol was from. But I over exaggerated in my head because I have this is I'm in my head that makes everything. Task Survives arrives on my I drink. I will lose all my muscle. I can't do anymore because I dabbled in. Drinking is a fourteen year old or a fifteen year. Old I would I mean I don't know what normal is but if a fairly normal like I wasn't obsessing over it but I definitely enjoyed the feeling I got from it and I liked it a lot but starting this fitness thing and that electric over and I was over is like I was super over just compulsive about it in so I was like. I can't drink but I started to feel as disconnect on why was human being because I was getting all his tension. I was the popular Guy Because I was definitely most Jack Guynn school where look the best but I still felt this emptiness inside like I still like felt just I couldn't describe AMAC wide title. I just oh I could just feel this discontentment saw never forget it. We went to a party my buddies I please don't bring in your brings ready to drink protein drinks and don't do that again. AM please do it. It's embarrassing and I'm like well. I really just drink one night. I'm like no I back and buys tomorrow I and he He said well. How about A about this Pain pill I was like. Oh I'm not in any pain. And he said no man they make you feel like you're drunk. You don't have any of the hangover. You don't doesn't dehydrate muscles and I was like I'm in and boom took them in once they kicked in I remember. I think I've been said to him on the way home. This is the feeling I want every day the rest of my life I was on cloud. Oh nine I loved it. He was like Whoa. Did you really like those. Like he was looking at me. Like you're kind of weird man and I can and I kept asking if you're getting more of those technologies stone. I'm from my mom and I'm like what are they call. And so I started asking people started asking bigger guys the gym before I knew it I start getting these connections and and I started doing him glop more and more in a started taking my car down to Tijuana across the border which by the way Davis in context from Salt Lake City Utah. It's like a fourteen drivers now. It gets re hour drive and go down there and it's a take up my door panels at the pharmacy. Isn't it stuff and full of drugs. I want them back on their in a drive through the border. I remember the first time I was scared but I had no idea. It was idiot savant. I had no idea the amount of felonies I was committing. A no idea how how I was going through state lines with drugs and like so after the first time boys okay. I'm GONNA say not just state lines. You're crossing borders like that's yeah I think it's a pretty big felony and then I that's when I felt like I had arrived. Not only was I felt this passion and purpose I was lifting and I was also a drug dealer. I hooked everyone up all the different schools. I thought I was the man an and like people that I had more money than anybody in still in high school. Yeah it was a senior in high school. Yes I I could just imagine feeling like you're probably I mean in circles like you're probably looked at as like a king like here's the Jack Guy. Good looking got money any able to supply all this like I mean in your mind linus probably like this is this is the dream right. That was the pinnacle I was like. Man This is et like I'm I'm the man looked at as the man and my parents parents didn't know they were suspecting. But you know that I was maybe partying. But they just didn't know the extent I was a super good liar really of manipulator course and it got worse never but it just progressively got worse. After highschool ended a lot of my buddies. I was using with. They did the responsible and they went to college in these. The kind of quit using you know they let us here and there. But they weren't addicted. I had developed an addiction in You know the first time I felt withdrawals I had. No idea was happening to me because I hadn't ran out the whole time when I started in using daily and it was awful and I didn't know what what they were. I thought it was getting the flu. I knew what withdrawals were but I didn't know they felt like that and it was awful and and I happen to be around some some older guys who had who had heroin and I remember thinking that it's a line in the sand. That is gross. I just do pain pills and and muscle relaxers like I do like that's gross. There's a line in the sand here and it was. It took about twenty minutes for me to feel worse and worse and worse than finally. Just say let's do it so the first time Aberdeen Heroin. It was right out of high school and I was You know an eighteen year old kid and A shot it up for the first time. And that's what I did. And because that's how they were doing it and it Iraq my world never never forget the Guy who gave it to me. He looked at me dead on the eyes and he said kidger life is never going to be the same and it was not a good would context around that statement and man like the truth of that statement I spiral deeper and deeper in you know ended up my first treatment center when I was. Let's see two thousand five so I was about twenty years old and was twenty because I went to that treatment center and A uniquely thought I was different. I was too young to be an alcoholic. I I would accept that. I'm probably a drug addict because I've track marks on my arm. It's not normal tissue cocaine and heroin every day and each you know out in the cold looking for the dope dealer. But I'm not in alcoholics. I'm too young to be an alcohol all just I don't really drink much since I was fourteen fifteen so I listened enough to realize okay probably have addiction. I don't have this full-blown thing they're talking about so I proceeded to Take to get out and start drinking and I quickly started drinking more and blacked out and during during that blackout. Apparently I got some cocaine woke up the next morning and it was with me and it was just like boom right back to what I really loved and kept doing that and it was just a vicious cycle the sum up from two thousand five till I got sober in two thousand twelve. It was just incomprehensible demoralization just over and over and over like would I went to four different treatment centers in there. I'd had seventeen bookings into local county jail And I was a full-blown Junkie and I would get sober and but still lifted. During this time I still still worked out. It was the I worked out and I would watch. ESPN at night to catch up on the aims. Those two things made me feel like maybe I'm not that bad. I was is functioning for a little bit of it. There were times where I was literally like odd. Do some heroin in in the morning and the afternoon and evening and I managed to golds gym. But you know I say all this but then I got fired from that job and then like it got worse and then I ended up losing my condo and then I ended up in jail and then when I got out of jail like this rejuvenated help I would. I would try. Try to do the right things. I'd get back into the fitness and then it would take over so I am it was. It was a lot of years of just the same repetitive cycle. And A and along the way you know I kept I kept going to Twelve step meetings and I don't know if you've got through sober through the twelve steps or anything but no I didn't know so Um yeah me might be my biggest. I don't I don't know how much we share. Prior to. This is You know I've struggled with alcohol drugs. You know throughout pretty much entire life never to the extent where I was shooting shooting. Anything up But maintaining functionable life in and it was for me. It was the darkest deepest thing was was porn. I mean up in up until February of this year like I mean I was consuming it hours hours a day especially at the end of last year. I mean it was just overtaken my life So yeah I You know part of groups I've attended You know a few a few recovery meetings And I I support the twelve step I understand the principle behind it and and I think can definitely be used if you follow them the way that they are and I know this is something that you've talked about a few times too. It's like When you first started? I think you you weren't really you're like I'm GONNA I'm GonNa do this on my own type of thing like I don't need to. Bald is exactly the way so Yeah I think as a coach night. That's maybe something that we could kind of. You know touch on here real quick. It's like importance of complete surrender complete. Follow a protocol in of a plan. Because you deal with this kind of stuff with your current clients yet no one hundred percent in backtracking on that a little like I would go to meetings in. Here's what I started to hear her. That the whole point of the the big book of alcoholics anonymous to the twelfth steps was defined and gain a relationship with power greater myself. It's pretty much sums it up. There's some some house cleaning. They're cleaning up the wreckage your past but it's really really about. I saw the word God in so many steps and I was like okay in. I felt fortunate because I I got sober with some people who hated God. They thought it was God's fault. I never felt like that. I was active in in my religion until I was about fourteen or fifteen gene and then obviously you know a quick going but I never thought any of this was God or Jesus Christ but this is my fall like this is me in so I felt fortunate for that and I heard that over and over so I went to all these treatments centers and they only work. If you're ready to work you know it just didn't work and it's no fault against them. They exist for a reason but but when I finally add sober two thousand twelve. I was finally ready to follow plan of action. And I will say this. The twelve saps what definitely facilitated me to get sober Ober what keeps me sober. Today is much different like. I have a men's recovery meeting my office. It is just a recovering guys addicted to porn. We have like everything it's just about. A fellowship in my spirituality has evolved to the point where I'm so grateful for twelve step rooms but I also know that there's just dot was the the basis to give me to wear him out today and now my evolution looks much different. I'm not on any a panels nor doth like a need to be my messages trying to much greater. Are you doing that. Philip is trying to spread and I'm appreciative for platform. Where I can talk about and just say God because sometimes I don't want to brush off any listeners or anything that especially especially if it's not a recovery podcasting have been a lot of fitness podcast? Tell my story and try to not go there but my relationship with emily father and what that's done for my life absolutely. He is the center part of of everything. I do in life like when I saved without my recovery. Nothing like I'll have nothing but without my recovery like there's layers in there and my relationship ship with God. Today is fundamentally the reason why I'm not only sober but thriving and happy so Yeah I'll take you back just a little bit today. Got Got Sober. Was I went to my grandfather's funeral and had been homeless for a year and never slept on. The streets was very resourceful and I say now that's when my entrepreneurship began because his hustle and grind it out there and I was always shipped. Yod make moves. I'd stay places. I am a job for a year but somehow I mean big habit and went up to that funeral and I'll never forget it that I You know my mom picked me up from this hotel. I was lucky yet. And I was withdrawing and it was sick and I made her stop at the dope dealers and through through that I went in and a God. She didn't want to take me up there like this. I was shivering shaking. I was vomiting. And she's really good codependence he was GonNa love me to death. She realized at the time but and I made her stop this good religious lady upstanding in her church and a major stop and then I proceeded to do it in her back see. I'll never forget a book in in the rear view mirror and she's watching me do it and like hit her like wow and tears rolling down her face and I could have cared less Intel. It hit me. I felt. Oh better that the guilt and shame immediately followed and I was like. Oh my and she's crying and I'm trying to hold back tears and normally like the drugs would kind of numb me. The and they quit doing that that last little bit and I believe that was you know people say. What was the final Straw? I started praying about two months before I finally got sober and my prayers were really all over just to God like I don't know if you're out there for me but I don't know like I'm I'm either gonNA eat a bullet or I need to try to get sober for the fifteen time like I don't know what to do. They were very simple but that simple act of reaching out man like it stopped working. I'm telling I couldn't put enough in me to fill. Well the whole like the guilt and shame. I'd usually only feel when I ran out of the drugs and the next day in the demoralization of that but I felt it in. I am man. He he started working through me and I believe that part of that was it stopped working like I would get high but I still had this. Shame and guilt and couldn't I feel like I can breathe some days because it was so overwhelming overwhelming so that night I got arrested and I'm so grateful for that and I believe that was that was divine intervention it was arrested and it was finally like Don on an what do I do because the which are going to be so bad. I don't WanNa face them. I don't have insurance. I can't go to a medical facility. Parents are done with me especially after my mom watching being me shoot up. She's like I can't be around you and I was arrested and I- detox. Worst nightmare happened. His sat on that jail cell floor of sitting on the concrete and Puke. In you know now just a mess and prayed and I remember feeling this feeling is that was laying there on the concrete in. It said like this is the last time you're ever going to have to do this it. This is the last time I heard that voice in. It's what got me through. This is the last time like walk through this. And you don't ever have to do it again if you don't want to and so I got out and you did something different and I went back to meetings because I had nowhere else to go to be honest and I followed a plan of action and I don't care what that if that the church in the Bible or the twelve steps or some kind kind of fellowship of people that were like minded there were trying to do right in their lives. That have been there and I had a plan of action in front of me and I remember thinking okay. God got got me through this because I can't believe I'm actually sitting here thirty days sober when I got out of jail and I want taxi do something different. I went right instead of left so to speak and I think that's why I love up coaching so much because I understand its application. It's accountability and it's education that had to be educated about the. My addiction wasn't just because I liked drugs. It's because I hated me. It had no relationship with with God or power greater myself In so I followed that plan of action and I got a different result like I started to an and I'll say that I say this all the time like when people are in a meetings or recovery meetings like if you missed the spiritual part of the program you miss the whole program because that's the whole point and I'm so I'm grateful that quickly I started I just I knew that was that. Was God in jail. Cell telling me is the last time you have to go through this last time. Yeah and I think I think you know. Oh kinda big part here like it's you know you're hearing like you know will you are at this point. You know you you open up. He began to pray in. It's a lot of people fall short in this. So as they send their prayers out in. It's not an immediate quick day society immediate response not like I asked him today and and it just shows up like like you heard it in but you still knew that eh like this is GonNa be a lot of work for me. This is going to be a lot of work for Brad like it's not like I. Just enter into this new programmer. This you know this this new phase in my life in everything. Everything is changes. Like I had to start working on me. One of the one of the best books I read this year was called unbroken brain in its by this The author is just my Salvador a salvo. Let's always I always mess up her name But so much of what people talk about and it's like addiction is a disease. It's this horrible disease that you're born born way than you have to like work to overcome and she. She poses the complete opposite argument. It's like no you don't have a disease. She actually rains it almost as a learning disability. Like you've you've just learned the wrong habits in it's GonNa take a lot of work to overcome in instill new habits so I think you know for for you. It's like understanding like yeah. Yeah God is with me. He's here he's leading me out of this but still gonNA require Brad to do all the were one hundred percent in. It's crazy when I was starting to pray in the last two months when it got ugly out there and got a little scary I got I was into amphetamines. By this point. It was the people in the circle abroad and there was kind of an evilness that I felt. I A a truly believe that there are certain. Drugs are little more chemically evil by nature they brings out this almost satanic kind of feeling so we talked about this The the most recent episode that we that we dropped was with A recovering addict Adam Adam vibe Gunston and he shares a story of having a conversation with a doctor her in talking about this spirit of drugs so everything you know everything living in the world has spirits and you know inside of them like alcohol. That's a reason why they call you know liquor alcohol spirits. It's like you're you're ingesting that spirit. And that's what gives you that happy joyous feeling so you think about in terms of you know these hardcore fettah means or or even heroin life thinking talking about the the lifetime that it's oak of that drug to kind of get to where you're at all the all the hades you know all the all the greed murder but it probably was involved at some point in their like you're ingesting that spirit and he tells them INCR- like incredibly vivid stories about seeing spirits. But yeah no I one one hundred percent. Get what you're saying here it's like I'm ingesting. Not just this little pill. I'm ingesting everything that it took to make this pill so man that's so powerful. Yeah you know you. You're so you're ingesting this that I've never thought of it in that way. So thank you for sharing that with me. Because it's so true and one thing I've one thing I've shared for me. It's like when I talk about appoints. No big deal. I'm just watching just enjoying it. It's like it's like no it's like actually kind of look behind the curtain a little bit and realize what is going on within you know within initially something. I'm extremely passionate about and getting involved in. Twenty twenty is no supporting some. You know some sex trafficking and you know human slated organizations because that is what's fueling knows there's billion dollar industry so yeah when you know if I'm on here and I'm watching you know I'm watching. People have sex realized that one of those people may be. They're not at their own accord like like they may be forced their then. You had the drugs that are involved behind this the abuse and it's just like it's it's it's just a horrible evil place to even think about being involved in so that's that's one of the reasons why ISO passionate about having a voice Against against the industry. That's awesome and that that's such a good perspective and spin on it because you know that's true through. I mean. Most people are not like well. I'M GONNA go have sex with a random stranger on film and and you know I'm totally fine with that. It's the money and then there's some nip In its drugs. They get beat. You know I just can't imagine too many people just one hundred percent okay with that. That are spiritually you know in line and sober and like Oh this. This is great and so there's a lot of man with the with the drugs that did it brought. There is an evil presence has started to happen and I prayed for that and I think when it stopped working as what I like like to call up meaning I couldn't get relief. I definitely was under the influence but I still was like you to. Your family won't talk. Aw God starting to work. But I didn't recognize that at the time it took me probably six months into my sobriety to look back and think wow like it's as bright win and make no wonder I heard that voice so clear the last time you have to do this. He was leading me up to that point and I'd never even made the connection until like the set about six months sober and you know. I think I started falling plan of action. And you know for me. It's I think however one get sober gets freed from addiction and can enjoy in thrive in their life. My I'm not dogmatic that you have to do with this way or that way I will say for me. A spiritual component of part is is a huge part of it that I if someone can get sober just just by simply more cognitive therapy and there's no Religious or spiritual project. My Hat's off you. I can't say I understand it to be on speaker. I think it's I think it's gotta be like no matter for me in you know. We've we've shared here on there today but it's like you gotTa have something that you're working towards that as beyond to who you are you know it's like you're you're you're you're you're held almost captive by not the drug but the feeling that drug is bring it to you and the only way to replace that feeling by you know service something that is bigger than you whether that's a mission of a company whether that's a mission of our family but yet I for me it's I I agree. Yeah I think there's got to be the spiritual side of it because you got to believe that you're that you're created in your you know your your here for a reason you know if not the drugs could have easily just taking you out any numerous times but you're still reading yourself standing so there's a purpose to who you are into To why you're here a man do not to commend you man. I think that's awesome. I think there's a lot the people who I still think. There's a lot of stigma or shame around. Let's say porn addiction like I'm looking at you. Good look do your head like but for you just set it so no matter of fact there was no shame in there. There was no guilt. That is your story in that because I didn't have that experience so I can't go help other people and spread a message but what I can is the things that you have gone through the menu for that man because I see so many people that are in recovery from drugs and alcohol that that are being that way but they don't WanNa make it a big deal because like that's embarrassing or this and that unlike the Shit I did get high you could class is embarrassing but as part of my story. Yeah I I really appreciate that man in in for me. It Psych Mike like utilizing the tools and skills that I've been given you know the ability to articulate a message in the ability to have a platform to voice out there but the adds a real thing and you know it wasn't an escape it wasn't I wasn't running to poor because I couldn't you know get girls or or have sex like I mean that was like that. That's a whole different addiction that I dealt with Besides the fact but I think you know when when people think about the stigma for addiction. It's like oases week or guys that like you know don't live don't work out out like you know not it professionals. A high level competitive bodybuilder placed fourth in state afford. I mean I've literally was a walking billboard for what a male physique wanted to be a but I still got trapped and I still got pulled into to this mess so yeah anything I can do from from sharing my story and just being a voice and having a platform to to where I can have these conversations nations. It's you know this is. This is here now man. I felt that that's awesome. Yeah Man I To this kind of Segue into like where I'm at today is I got back into the fitness industry. Now only working in it but also Myself you know really taking charge health and and you know when it got so where I was forty pounds underway. I was unrecognizable and Belt awful right just physically. Even the first couple of months in so fitness has been bidness. Literally he has has in a way saved my life. Because it's taught me so much about who I am and I've seen in that doesn't mean the last seven years it's always been this healthy relationship. I- I competed a couple of times and the second time the first time was great. I DIG Ray. I felt great. I kept my relationships. It was this bucket listening. I'm going to do the second time some kind of sweatshop and and I got very very selfish I got. I ruined a relationship. I was in at the time. I- destructive people's lives. Because I only cared about me I ruined some friendships and I felt lonely. I remember looking the Mir thinking. How do I look so good in field like not only physically associated but also just feel empty in? It's because I was just put the gym. My biceps is how small my waist became. I became I became my own God and that is never good recipe for happiness enciso. But you know I I've learned from that and that's what people ask me compete again. I'm not sure I would have to see on a really good place to do it. I used to say no never and I'm just like I don't know I enjoy the sport but for me just maintain this happiness. Now that I've started a business so I got back into what I'm doing now and I worked for a different company and I left there In in February will be three years so I started keen attrition in February of two thousand seventeen and it was the same feeling. I haven't got sober. I was scared. Didn't know if I could do it. I Oh really really doubled down on my spiritual practices my prayer my meditation journaling reading and I walked through it and I was terrified but I have this grace walking through a just knew that intuitive feeling in your gut call it the Holy Spirit call it whatever you WANNA call. It was there and it was like this is going to succeed. See this is GonNa work so I watched through that and I'd never actually been grateful truly for everything I went through and that was at four years sober I'd like I. I'm grateful but not like to the inner beings my core like. I'm so glad I ran around on the streets for a year and when I started this business I finally got grateful because I realized just man that was my like that was my segue entrepreneurship at all happened for a reason if I could get hustle and grind out there I could do this. I didn't know crap about business. I only watch shark tank. I am followed Jerry. Banner Chuck That's All I knew but I just went with this faith that it was going to work out if I put in the work just like when I got sober and I made a ton of mistakes we really screwed up on some things but it just kind of kept progressing and like I just know the God had a lot to do with that because that feeling my God was just so strong like hey chill out. It's okay it's GonNa work out you'RE GONNA make mistakes that's okay and When I finally gave myself the grace to make some mistakes and not be so hard myself? My business started to thrive more. And you know it's turned turned into something I I never really pitcher to being and now it's funny I look at it and I'm like Oh we're just a little toddlers learning to walk this is GonNa grow into something bigger but it's just one day day at a time we're doing a A live my life on passionate and just in the last year of really really realized I need to share my story more so I appreciate platforms like this because recovery is possible to get back from the chains of addiction to like. You can't breathe. You can't live with it. You can't live without it. You can recover yet. No an in incredible and Yeah I Kinda WanNa now just segue a little bit. It's actually let's let's talk about nutritional you know Incredibly successful business. Yes you have. You know you've grown this team coaches. Yes having incredible mission out there built around these four pillars. So you know was this. Was this all kind of you. Know the making being a brat or were there. Were there people involved in kind of behind the scenes working with with you to To build the salvation. No I mean it was really just myself and my sister is my operations officer and she you know together we Kinda bike built this format just always kind of changing and evolving in. You know we kind of realized. There's like the fitness side. There's there's nutrition side. There's accountability is a big piece in this and I'm big on accountability because I had accountability with people in my life when started changed my life. And I think whether you're in a church group whether you're in a recovery meeting with whatever it is at accountability is just a crutch that makes stuff happen. Just and so and then I realized the fourth pillar was mindset. And if you coach which with me. You're going to hear me. Talk about spirituality. Lot and you're GonNa hear me talk about. I don't try to tell them. You should believe in this or that but if they are you know belong to a church I really encourage them to jump into it in a mess. They look at me and I think has anything to do with business as everything. Because they're all tied together said Pitcher at his his barstool four or legs legs when one gets off. You filled a little bit. You're like a little wobbly to gets off. You're playing this dance trying to sit on it and three falls off you're done if you've fallen for and so so We built it around that and realizing that. That's what's going to a can't be just about putting someone on a diet it's gotta be much deeper than that. It's it's so much deeper because what what you learn through fitness helps you evolve as a human being if you view it as an opportunity is at its so much growth. That happens when you're pushing yourself the limits. You didn't think you could and Mike Clients and start to do some spiritual practices whether that's meditation journaling. Prayer Church attendance. Whatever it is their results are better? Could you start living in alignment with your truest self. And so that was just in the last year that kind of created the four pillars before was just like. Yeah we can help you get super shredded and I realized that's not what I WANNA. I do sure we can do that with clients. That's their main goal but not not many and so part of me sharing my story so much as understanding people but the background behind key nutrition. It's not just Mike. I'm like wow the guru say that mindset in having a spiritual connection is really good for you. I'm seeing it like in my own life. I've lived in. I know that it's it's the cornerstone on that kind of makes everything happen. In Jesse worked together so we were constantly evolving and changing and I got ten coaches to work for me and trying to show up as a leader for them is is highly dependent on how I'm doing my own personal growth in my life when I slack on that leadership slacks than they sought. Then there's discontentment in the workplace so it so so I realized I have even more responsibility today to make sure. I'm keeping up on my end of the bargain when nobody's looking through personal development or spiritual growth so I it can show up better for them. Yes so let's Let's dive deeper into that. Because I think that's you know we can maybe find some real kind of actionable. Stop here like like. What are some non negotiable? That Brad has in his day or or in his week. That helped prepare him to show up as later to show up as as coach are you. Are you a person of morning routine. I'm very big on having more entertainer like two hours dedicated myself every single morning. So so what. Are those negotiable in your life. That make sure that your setup to show up who you need to be for your team for your clients you're for your family Morning or team for one hundred percent of non negotiable for me I do it. That was one of the things I was told early on getting sober. That was extremely greenlee. Important and for whatever reason that resonated with me of the other things did not I was suggested to not date may be for a year to try to get an dated two girls not at the same time but back to back but that one I was like that makes sense to me. I have to start my day of when your morning when your day all these Kinda cliche things but it resonated. That is a non negotiable for me It's even caused fights it's with with people I've I've dated in the past where they come down and a kitchen and I'm trying to talk to me. I'm like Woof You get getaway so I need to do this and so I've tried to be flexible within it lately but it is one hundred percent something I do every day and that part of that is journaling. I read daily devotional thing and and Journal I'll do some meditation which is not. I don't Sit Indian style with a rock and a I just it's my picture on your website. I'm looking at you. Sit Out and we have to get off off of them embarrassed by it. I'm like I'm like I'm like I hadn't talked to yeah we had just been connected through Through social and I'm like this dude is not meditate in the middle of the gym. I was like come on. That's why I'm embarrassed by the anytime. Someone takes like especially seen instagram posts. And they set their phone up and take a picture that meditating on Mike. We all know. You weren't meditating 'cause you went and got the pitcher like exactly. Yeah but but Yeah it's a huge part of my That's it's an absolute non negotiable for me is doing that because I've seen the repercussions when I don't do it from buying for a day or two the third day little little irritable and discontent the fourth day. I'm Kinda snapping on people that I I actually to be honest. I don't think I've only four days like twice usually. It's every single morning. There's an occasional morning. I'm that creeps. In where if got blindsided and I scheduled the call at the wrong time. But I'll do it later so maybe it's not a morning team but I do my routine at some point during the day and and but I I try to make it. I mean the morning that is absolutely not I think it is crucial in success. And I believe if you win your morning you can have a better chance of winning your day. Yeah I think they'll come up and wins very subjective to you but yeah I can on a percent I mean outside of that like that is one hundred percent of non-negotiable other outside of that it's That is definitely the strongest one. Good Question Yeah. No screen just just circling back to to what I was sharing previous about the unbroken brain. It's like I putting these little routines and habits place early especially for somebody. If you're out there and you're you're you're trying to get out of a dark place. You're going through recovery like instilling stealing a routine where you are doing things every single day. non-negotiable GonNa you know over time like those are going to become so simple that you're not gonNa have to work to do them but it's going to be able to add on habits like I don't think it's important to start with like a two hour morning routine like just start with one or two things that you say do every single day whether it's no fire two minutes one on one of our One of our episodes you talk about Just doing one push up committing to doing like if you're trying to get started on fitness and you're not doing anything right now. Don't commit to doing a hundred pushups chips every morning or even ten. Just commit to doing one because you know you can do one in the chances up once you're down there and you're doing the one you're GonNa do a few more over time that's going to grow and evolve in just continue. Continue to add on so one hundred percent. I think it's really important point. You make because I started really small eyewear three intentions for the day. And they prayed it took took me all of two minutes That was my first introduction to a solid morning routine. Yeah and once I nailed that down and I started to feel like Oh this is good. I used a little bit of writing and so not only might like it just grew involved. You know and I have to say this that I've hit points where I was doing to our morning routines and it was probably the best I fell and I've stacked a little bit too much on my plate relies on. I'm realizing that going into twenty twenty. And so we digress a little but he unit my morning routine now is probably twenty minutes it. It was up to two hours. I put too much on my plate. I'm noticing it really was helping me a lot but I'm still doing it so I still feel. It's just an. I'm going to ramp that. Backup up in prioritize it a little more so important messages. It's not about perfection it's about consistency and sometimes it looks a lot better sometimes is better. Maybe maybe more You know detail than in you know and longer and doing it in so I will try to make that point to that. There's ebbs and flows with all of this season since we all know. We all have seasons like you and I mean we have you know we're previous bodybuilders. So there were times in our lives where you know. I'm sure it was two a day in the gym you know morning Cardio and evening workout or vice versa whereas now we can probably maintain a you know decent Zeke to what we would have maybe during an offseason with maybe four to four to five days of training thirty forty-five forty five minutes A week but if we ever wanted to dial that back in like yeah we have to recommit Two more frequency and you know like more volume or intensity etc etc.. So yeah I I think it's just understanding where your seasons are in phase of of your life you're currently and let that kind of dictate where you're GonNa go and I'm sure you share that kind of stuff with your your clients like coming coming on a new client. It's like we're just getting started. This is a this is gonna be a transformation so for these first three months like I need your full commitment to this and once we get you to a to to a nice little point like then you can kind of look at maybe adding in you know a night out where you're getting some you know some better you know treats or whatever however however that's coach but yeah I think it's it's important to like not go all in and understand like like this is going to ebb and is GonNa flow and change you know throughout my life so so awesome awesome point there Yes I mean Like I said just just incredibly blessed to have you here today Raton. I think we got a lot out of out of your story and I want to be courteous of everybody's time China's we're kind of wrapping this up so just kind of a few no final pleasant as we as we come to a close here No so your your fitness now. I know you're not not bodybuilding ability anymore. You're not training. What is your current routine like and and where fitness kind of fit into your life absolutely For something Adam. y'All man appreciate your time as well In as far as where my fitness looks like an act which was just Writing out a post To to make later today about this like the five reasons. I go to the gym and Mike. My fitness book a a lot. Different in one of those five is aesthetic still and I think anyone who says they don't WanNa look better just by his is the truth right but Man For me so I'm still working out five for six days a week You know and before was about four or five but lately it's been a little more and You know I'm going through some personal stuff. That's there's there's some changes happening. There's some things happening And for me I ramped it up to six now because anything with my body. It's because it's really. It's such a good mental release for me and so but I would say out of those six five to six days a week probably three or pretty intense. I'm thirty five now. I'm not twenty five anymore You know I'm not on a bunch of the Andrew Jans like I was in my twenties so I try to understand the delicate balance between you know pushing myself and not going to hard I I really care more about how I feel today the so now I look and soy over train but on an. IM super consistently like all the time. I allow myself Some flexibility I I track my own micros and Not obsessively tracked them. Especially when I make some changes. I'm pretty dialed in. But to be honest because they do this for a living I feel a huge responsibility to make sure I'm walking the walk and it's not about having to be perfect or like. Oh my gosh. What if I went like it's not about that? I can go often. I could probably eat like crap for a week and not notice a huge change in my body right away. But I don't like how I feel and I feel like I'm kind of the pot calling the kettle black so I feel responsibility. I he probably I mean I still really good all the time. And but that's because that's what I do for a living and coach people on food and fitness and I feel like man. I don't WanNA invest my money with a broke financial advisor right exactly. Yeah I battle with a pasta imposter syndrome. Quite a bit as a been a coach for for a handful of years. It's like a lot. What I talked about was yeah building muscle using using your physique to catapult you to a greater version of yourself like this message Edmund Sharon for a really long time and here I am like I'm hiding hiding this deep dark secret of something doing kind of on my own time so definitely understand like a like the feeling of the impostor imposter syndrome Yemen? And you know it's funny as Guile Al Myself in this kind of complicated split but it was gonna be really cool and it was some advice from from a guy respect a lot who who is great with training programming but but I honestly it It got to. I like to go to the gym because I enjoy like. I don't have the set schedule that I can't make it here and then I'm GonNa screw up this day because then I over trained under trained and so I have an idea of what I'm GonNa do when I go in and I had those body parts picked out but I haven't made it to obsessive by backed off on that because I just like going to the jam and if I get thirty minutes a day great if I can count out an hour and thirty minutes I feel great. Awesome really read my body to like. What's my feedback telling me Emma? I haven't been sleeping that much this week. And that's because I've been going to artem business and so I know I didn't train very hard. Today's but I went in there and I got some blood flow and I felt good I did will cardio which is really weird for me. But I'm trying to get in this place of listening to like what am I feeling and So I think it's really important to but yet man. I'm I love fitness. It's my way of life. It's not about Motivation I think motivation is so fleeting I think so. Many people rely on looking for motivation to get them through at a at a client. Ask Addi stay some motivated all the time and I said what gives you impression on motivational time. She said well because you this day in and day out. I said it's my reality. It's not mode. which is what I do? It's like when I shower our every morning against my reality. It's not motivation. Motivation is super transient by nature. It will come. They'll go the days. I actually feel motivated in the gym. Unlike yes S. like score. Because I know that everyday is not like that and so I think there's a misconception and when you start to do day in and out it just becomes a reality as what we do. Yeah I ah I love that And do you know my lettuce. Oh yeah he has an incredible saying that he uses her in and around motivation. It's like people should never want to seek motivation because motivation is motives. It's like tactics that I can use to make me feel a certain way could possibly get the job done. It's like shies away from motivation. He wants inspiration because when near with inspiration. You're in spirit so during the spirit of feeling good of wanting to do things but yeah love your perspective on Dude. I'm not motivated at all. It's like like but this is just a part of my reality. I knew I need to get these things done. That's an incredible kind of Life Mental Mental Paradigm Shift Yeah I'M GONNA I'M GONNA I'M GONNA steal share share stole from someone else. We all swear to go real world we absolutely. Yeah I mean that's that's that's why one of the results are the podcast. 'cause I just wanted to have conversations with awesome people's People's I can steal their stuff and use it on my own in India. That's why I've done. Ninety up says amounts of around like Latin. I'm taking Adam taking. Yeah Awesome. Will it wouldn't be a a full conversation in the middle of December. We didn't talk about these two things. So I knew your success launched Manure Yavuz somebody that set goals and look back and reflect on deny compass what I wanted to so I kind of have a two part question for you right now. Is You know as you kind of. Look back on. Twenty nineteen with nutrition in your coaching. All the work that you're doing. What's the number one thing that you're most proud of accomplishing shing this year? And then I know moving into twenty twenty. You probably have some things that you've already looked for and set goals. What's the biggest thing in the biggest? You know goal that you've set for twenty twenty so for two thousand nineteen. I think within within the company you know we hit the weed service two thousand clients in. I think we hit that. In April nope August August and that that was a super big milestone much more than obviously the bad equates to revenue understand that. And you know I. I don't even like to talk about it because it there people look at it they were. Were I think within this week. We're going to hit seven figures this year in total gross revenue which sounds way cooler than it is. When you understand that I've ten coaches that I pay out percentage? I have big overhead. I- fulltime media guy of this but that was a cool milestone but getting to two thousand clients show. Oh is that we have done this the right way in in two and a half years at that point we had service two thousand clients showed two thousand lives. We were hopefully able to impact in such a positive way and I was proud of that. Because that that that means that people like as they keep sending people in and that's been that was really cool and you know Within my own personal growth just going through some diversity in my personal life and the grace. I'm walking through that and that all boils back down to doing a morning routine even when. I'm not motivated praying when I'm not going to the gym when I'm not motivated. All these things built up where I finally I hit some turmoil. And I'm I'm intuitively seeing me handle these situations differently and that's a god thing not abroad thing. I put in the work but I know there's this greater good and so and for twenty twenty man. I'm really looking to spin off and and You know emphasize my personal brand war. I was using social media here and there in the the last couple months. I've been going hard funniest people say. Well what are you going to do with that yet. And I don't know I don't know and I'm okay with that. I know I need to share my message more. I need to educate people more more on fitness. I also need to throw in light. You can recover from the seemingly hopeless state of mind body like there's these messages and I'm really excited to see where this pivots into and I could list the things. I'm kind of thinking but I'm just super excited and I don't need to know exactly where it's going to go. I just know any start putting out value in creating impact back not asking for anything not trying to sell anything like just start giving more impact and now will lead into more some super excited twenty twenty that way. That's incredible rather and awesome. Awesome answer to both in. You know it's funny because I'm listening to Zig Ziglar audiotape. Earlier this morning part of my routine Is usually the reading listening to some some form of audio and Going going back to your big win for this year. It wasn't that that revenue milestone because. Yeah I've worked in digital marketing work. With a lot of entrepreneurs I worked with a lot of companies that are scaling and growing linked to seven figures. And beyond. But when you look at like what they're spending to get to there it's like it cool you made you know ten bucks that right. But they're out they're flashing seven-figure mark but the fact that you said the biggest thing was the amount of people they manage shows like real classy who you are as a person so commend you for that and I think you know tying back to the ZIG ziglar thing. It's like he uses he. He repeated this in an hour long audio he probably said it half a dozen if not more times. It's like you Wanna get everything you want out of life help enough people get everything they want. And the effect at that you're driven by the amount of lives that you're changing amounts of people that you're touching shows why you're a successful as you as you are in. I know that twenty twenty and beyond is only gonNA lead you to so much more so absolutely minutes. That's incredible incredible way to kind of look back and reflect upon years. I appreciate that Yemen. You talked about you know growing growing your brand and growing your audience dancing kind of Princeton content out there so so where can people find Brad. where's he hanging out the most. You know this kind of point people in a direction because I know that people wanna look more into after after they here this conversation today absolutely men. Yes hang out on instagram. The most is just at the sober bodybuilder All all one word. I'm not a bodybuilding anymore. But you know the tagline a stock and it's it's so I'm gonNA keep it so and my. My company's website is just key nutrition dot com. Okay and you know if you're interested in more of the fitness and nutrition side of things too You know our my podcasts deke nutrition podcast and so two episodes a week ones educational ones. Guess would love for people to hop on and listen so often. Yeah and I'll I'll make sure to link link all that stuff down below in the show notes as we kind of you know kind of wrap it up here. You know I I've shared with you and I truly believe that we were all created here for a purpose in this world in you know when we have the ability to to Harness Napalese for that state in something beyond ourselves but then take control of our physical or our body and we can ultimately create our own super human life. And that's kind of been no the thesis in in in motivation behind the show so if he had a summarize no living a superman life's You know in a sentence or two as we wrap it up how would how would you define a supreme nice suit. That's a great question. They get super human life for me. Is You know when I think about in the context of people that leave legacy lived a super human life and so when frame it that way you know I I I want to part of living a super human life is giving more than you took you know and staying staying in gratitude because I believe gratitude is just the Indiana out for life. It's I've never been truly grateful my core and also super resentful that moment. So for me it's Creating Impact Act and giving value and and dumb in staying grateful along the way man incredible and in brother. I appreciate everything you do appreciate everything you're doing. Support you one hundred percent Dan. I'm excited for for what twenty twenty is going to bring for you and your entire team at key. Nutrition's all I'll be a I'll be touching basically demand and in following up so the older labour we're coming on and share share today guys guys. We thank you so much for tuning in to another episode of the supreme in life. If you found value in this episode. You know that there's somebody out there that is maybe needs to hear. This is near the story. Totally lead them out of one of those dark places All we can ask that you do as please share this podcast with just one person and if you have not done so yet is the person I'm listening to the to the podcast. Make sure to leave us a five star rating and rigor you on whatever podcast platform. You are listening on. But without that guy's frank rich here with Brad sober bodybuilder. We Love Y'all and have a great day.
29 May, 2019 Episode 723 The Surprising Science of Sex
"This is too. It's this week in science episode number seven hundred twenty three recorded on Wednesday may twenty ninth two thousand nineteen the science of sex. Hey, there, I'm Dr KiKi and tonight on this week in science. We are going to fill your head with helpful dirt fish skins and sex, but first twists is supported by listeners like you. We thank you for your support. We really couldn't do it without you. Cool Lamour disclaimer? Disclaimer sex. It's that thing. Your parents did that made it possible for you to not want to think about your parents having sex, but they did it and did it in such a way that made you possible. And that is not the only reason you exist. But that's the beginning of the story. Turns out your grandparents also had sex if not for them having sex or parents would not have been able to swap chromosomal chemistry in the first place, which means that at some point your great grandparents, all eight of them needed to get busy, and just the right way to set in motion the sexual behaviors of offering that again, a matter how you choose to or choose not to think about it is how you got here. Saxes the reason just about every person, you could ever meet is meetable in the first place, and with all this sex is coming together of more than just two individuals. It is emerging of genetic information of. Tens of thousands of generations of hominids with N flexing and outmoded ING of jeans with specialization mutation epi genetic adaptation to put it most. Bluntly, the simple act of parents having sex is the thing upon which most of life, love and Evelyn of life on this planet is based that and this weekend science gumming up next. Got kind of. Learn. Discover that happened every day. There's only one place to go to find the knowledge. I, I wanna know. Science. Steve KiKi, and Blair and a good science to you to just in Blair and everyone out there. Welcome to another episode of this weekend science. We are back again to talk about the wonders of the world that are filled with scientists curiosity and information all the things that we have discovered are still discovering the questions. We're asking and on this week show, once again, there's a great show up ahead. I have stories tonight on what makes us human, and what might make us happy. Also haven't interviewed this evening on sex chromosome science. It's going to be very thrilling very sexy. What do you have for us, Justin? Oh, that's a great question. I have a coral acid trip. I have some dirty fat news and why. Anatole ze went away. Drop in some coral this evening and Blair, what is in the animal corner, I have porn Greb bats splaine with that means later, I have fish skin and I have heard Alie hungry. Chimpanzees? We always love a good. Chimpanzees story. Well, you want anymore after tonight? All right. I love it. I, I am. I am waiting waiting for that one. But before we jump into the stories and all this fun stuff. I would love to remind you that if you are not yet subscribed to this week in science podcast, you can find us on itunes on the Google podcast portal. The apple podcast portal Stitcher, spreaker Spotify Pandora of radio dot com. Tune in all the places that podcasts are found. You can also look for us on YouTube and Facebook's or just visit twists dot org. And now I would love to introduce our guest for the evening. We are joined by Dr Melissa Wilson, and she is an associate faculty in the bio design center for mechanisms of evolution and assistant professor at the school of life sciences, Aaron ONA state university, her research interests include sex-based biology. She said he's the evolution of sex chromosomes. The x and the y chromosomes in mammals why new tation rates differ between males and females and how changes in population history affect the sex chromosomes differently than non sex, chromosomes without me further ado. Dr Wilson, welcome to the show, thinki- so much for having me. It's wonderful to, to get to speak with you. We talk a lot about the biology of sex. Blair brings lots of stories to be animal corner about sex in the animal kingdom. We talk about human of Aleutian. We're always always discussing this topic, but it's really good digging. Someone who is an expert. How did you come to study sex-based biology? Oh, gosh. It was kind of twisting path. So I did my undergraduate in mathematics actually, and I did a, a summer research experience, where learned about some biology, and I ended up applying to a bioinformatics so biology in computer science program, and they let me do rotations in so I did a rotation lending about yeast genetics, and it smelled like baking bread. And it was great in. I did a rotation learning about Arava Dopp, CES, which is a mustard weed and unedited version with Dr Katharina Mika studying sex chromosomes was over. I knew that I would be studying that for the rest of my life. I have been. There's just there's not a point where I don't think about that or relate to things to to get back to your sexy. You can't have sexy without exit y so kinda where I'm going. Bringing it all together. So getting interested in the mathematical informatics side of biology, I think coming from a biologist prospection perspective. Everything in my life was always wet and squishy. How, how is it to study to study biology from this, this other perspective of were looking at the informational side? Yeah. I think that's the thing win when people come into lab. And they asked to take a picture of need doing my lab work rate. They want me to put on the lab coat and go into the wet lab and show them some samples and. No, I, I do this. I, I work on the keyboard, and we sit on the computer, and they're different kind of thinking about how scientists done, but it's where finds is going in the future. All of the genomic testing, when we look at genetic ancestry from look at risk factors when reach too. Think about causes of disease, right? We're looking really not anymore to single gene rate, or looking across if we do the whole genome, six billion, incites and then we look at multiple individuals. So we're the maybe ten thousand individuals one hundred thousand individuals across six billion sites. And you can't do that by hand. So you have to do it on a computer right programs. We look at things. And if you come to my lab all concatenation file to the screen, it'll in the matrix -ough really cool. And you'll be really impressed. But, but I would never really do that on my own other than to just feel like maybe I'm not so big of a nerd all. In doing the sequencing. One of my favorite things is alumina on their next era. Sequencers the machine makes a really happy sound when you start it run. It's. And you get this, like something's happening. It's really exciting for g Nomex. From an evolutionary standpoint, your, your perspective, also, which is better sexual, or a sexual reproduction. Oh, gosh. Not it. In fact, in next week, I'm going to hold meeting by the American genetic association on sexual in a sexual reproduction because we still don't have great ideas about. So we have lot wasn't great ideas. But we don't have answers to qui- has sex, evolved, so many times, and why does as sexual reproduction persist in why do some population switch between sexual in as sexual end. If you've stuck in sexual are you really stuck can you get out of it? We see whip tailed lizards with completely female population, so they got out of it. You know what do we do? Yeah. I don't know. And then you have animals that job jump in and out like the Anaconda the New England aquarium this past week who went through parthenogenesis and had a virgin birth. Yeah. Or just what you're studying right. Reused the flip back and forth. Yeah. No, I think it's fascinating. Yeah. Such, it's such an interesting question. Because when you think about. All of the life on this planet. There are so many different strategies and his. But I think it's a fascinating, one, evolutionary fitness and survival and. More generations is the best thing, which is better, but we started talking online, because I came across interesting facts about platypus reproduction, and their genome, not only is as interesting as their exterior, but they also have ten sex chromosomes. Why? So we accent why. And then what an x and y an expert inex-, what so exit? Is a term, we use that refers to any species where the males. So the sperm producers can make again, eat a sperm with either one kind of chromosome complement or the other. So in x or a y but it could be to exit into wise or in the case of the plot A-plus. Five exes in five lies. And, and the platypus gets. All of this press. Right. Because everyone knows about the plot. Plus, in it's exciting in its egg, laying mammal in its door -able. But there are other egg-laying mammals the kidneys as a, a what we think happened. Is that Plotaikov syndicate in the common ancestor? They got one exit, y chromosome pair, and they added a second pair, and then they ended the third pair and then platypus diverged from the kidnap, and it added a fourth pair and a fifth pair, but not to be outdone. The kidney added a fourth pair independently. It added a fifth pair, and it locks one of the wise. No. So there's nine female kidneys. Have ten x chromosomes and mail. Akita's only have nine is their only claims of fame. What else I read? It's all the attention and the poor can no. This little strong and being. And they. Yeah. They also lay eggs and they. Yeah, they're, they're pretty awesome. But not that the plot A-plus is not awesome. But we don't now about twenty percent of the whole platypus genome is. Wow. Now in a sex chromosome in one of those ten. Chromosomes as opposed to us where it's five percent. So it's, it's pretty exciting. So those chromosomes are very important to them of for us. I mean when you're looking at the sex, chromosomes versus the non sex, chromosomes and trying to determine their importance for a species, or at forever Lucien of species. How, how do you start to figure that out? So we have some things that we used to think were true, we used to think that if you became a sex, chromosome, eventually, you would one of the two sex, chromosomes would decay over time like are y chromosome is much smaller than our ex the, the human x chromosome has about eleven hundred. Why has about twenty seven unique genes on it? This is this is what thing a science parent is like. Child. Children had small animals and large animals. And you figure out time management sometimes. But one of the things that I think is maybe most dangerous to people who don't study of Aleutian all the time. We're don't stink about. It is to say. What was the purpose of this? So it's a adaptation is a very strong force rate, but many, many things happen because they didn't hurt the species enough. So it's not only evolution of the good enough. That's probably what it should be not volition of the fittest. It's like evolution of the good enough, but also those suggests we in populations with a small enough size if you were good enough to get some, you would have kids. Right. Like, that's that's it. And it doesn't matter if maybe your cardiac output, wasn't the best in it doesn't matter if you weren't the most beautiful or you. We carry a lot of pieces in our genomes that are there for no, good reason. We'll, especially if it's something that shows up after you've reproduced. Right. So there's all sorts of things that show up after you've already given your genes the next generation. So it's kind of moot, yet, then they can't even harmful right? So it's not only that there's neutral things floating around select the Nutro things, there's dilatoriness things stuck around and things that are trade-offs, right. Something that maybe was really good and helped you be have a ton of reproductive success, when you were younger, but that same thing could also be harmful if suddenly now you're living to be seventy or eighty or ninety years old. So. Yeah. So that was not a great answer to your question. But that I, sometimes don't think about exactly, I think about what's important on the things that have been retained on our very, gene. Poor y chromosome, and are those things critical and it turns out some of them really are. There's a few of those genes exit what used to be identical. And there's a handful of those Shane's roughly. Let's say roughly seventeen of them that have a copy on the x and a copy on the why. And if you don't have a functioning copy of the x y linked copy like you don't function as a human like the UAE lost pretty much everything could other than the small set of things that we really need, except for one, gene, which is a PHD student doing some research. We looked at how all of the genes are conserved on the white chromosome, and there was one gene Ammiel y Amelia Jenin wide has excellent copy Mula gen-x, and the excellent copy is involved in helping make the enamel on your teeth. And if your excellent copy is broken than you can get Erkan enamel on your deciduous teeth. But if the wiling copy is broken nothing happens at all. And in fact, some human populations have totally lost the wiling to copy deleted completely deleted in some human populations. Why not when there might I care so much about this? I care so much about it, because it's one of the few genes that I think we might lose on the white chromosome, and it is, or at least was for almost all of our forensics history. The marker that people used to try to sex, the sample, they would say what? Why did they not talk to Evelyn string biologist? We could have saved the day. But no, the one gene, that they chose the why chromosome as the marker for the forensic kits that we use to say if you have this marker, you probably came from X Y individual. If you don't you came from an individual in the one, gene, the blueberry, Balaji tells us is gonna be lost or already is lost from the white chromosome. Thing it's already missing from some human population. I hope you don't have serial killers listening to this. Probably do travel. Do. Why is it though? I mean, the we've heard where there have been stories through the years that the, the why chromosome is disappearing. And you would look at the number of genes that it has compared to the x chromosome, and it seems like it. But then, then you, you see these very well. Conserved linked genes that fem- absolutely important. So then maybe it's not gonna disappear. I mean, what's happening to the Y-chromosome chromosome? Why is it shrinking? So we think we think we know the why it's drinking, which is that every other chromosome, chromosome one, you get a copy from mom and a copy from dad, and they can swap DNA to fix errors or mutations chromosome to some three, but chromosome Wyan ex they can only swap at their tips, and they can't swap on the rest of the chromosome. So if there's a mistake on the y you can't fix it in x ex- individuals. They still have to X chromosome, so they can swap so the Xs fine. But the white win it accumulates mutations or deletions or even insertions a can't get rid of them. And so we think that. But when it comes down to it if we lost the why chromosome it wouldn't even be a problem, the y chromosome is not males. What determine what we care about is whether individuals are developing testes in making sperm, and that can happen, if you move as our y to another phone, it can happen, if you move a chunk of genes there's been species. There's a spiny rat in Okinawa that has lost the white chromosome completely males are ex not, they just have a single X chromosomes, and there's define the populations are totally fine. So when it comes down to it, we're not terribly concerned, whether we'd lose the the why is just a home for jeans, and, and that home. Those genes can find a new home, what we can have Neo sex chromosomes. We get brand new sex chromosomes evolving now. So. Yeah. When you look at I mean, there's, you know, in inevitably Evelyn, we have these diversity of Liles and diversity of, you know. Designs like with the platypus they have ten chromosomes and you start to talk about like the kidney now getting another one, and then losing one and, you know, it's a very dynamic system. And I mean, how I it just it's, it's, it's really stunning to me when we think of our chromosomes as something that makes us human and makes us, who we are the possibility that they could that they could change, and that we would still be human? We are fascinating. Yeah, I think we get so we get stuck in list idea. That is genetic determinism that your genes determine who you are, and their chromosomes determine who you are. And that's really not true at all. If we think even about sex, chromosome copy number variations across humans. They're not uncommon so individuals who develop overseas and are assigned female birth, but have a single x chromosome ours, communist one in twenty five hundred. On the planet really Turner syndrome and individuals who are assigned male at birth, develop ESTES, and have two x chromosomes ally is kleinfeld, and that's his communist one in five hundred humans. So these things are not uncommon in. That's just the gross when I mean grows like large Bros because they're super cool chromosomal variations. And then we can have individual genes that are moving around. We can have genes that are turned on more than typical genes that are turned or reduced freshen. So I really try to avoid saying something's normal or something like this, this makes us human because there's just so much variation. I love that used a Liles also. That's probably one of the things I love most right variant of gene, so many variants, so many variants. And so we did a back of the envelope. Calculation once about. If you took every single site six billion sites in the human genome, and you took the average mutation rate, and the number of people alive on the planet every single site in the human genome would be variable in more than one hundred people across the whole planet. If you could sequence everyone on the planet, every single site in the whole human genome would be very -able in more than one hundred people. So what's noble? That's just that's a lot of diversity right there. What you're talking about, too, is, is, this is the thing that we really hope that genetic code would be is an absolute behind the scenes blueprint from which we could solve every mystery cure, every disease and predict everything that would come from any individuals code that they had. And what we've learned is yet. This is a it's. It's the plasticity is there as well as sort of cascade effect of, of, gene's working in tandem with each other, too. Have different affect. Yeah. One hundred percent. Yeah. I mean we were. Yeah. Human genetics. We lied. Yeah. Definitely my teeth. Okay. We didn't. Right. What we thought we were gonna figure it out. We did. And when I started so the number of genes in the human genome has changed dramatically throughout my experience in genetics. And, and it's still changing. And I just hope that we start to do a better job of appreciating that variation in exactly how things are interacted. So that we, we actually can't, we have made tremendous strides in trading, a lot of human diseases, we have, and I believe that if we start to take a step back from the single gene single phenotype, or single syndrome model will start to solve or at least find treatments for more of these is just it's gonna. It's not just a puzzle anymore. It's it's like a multidimensional. An interesting correlation. I think of when I think of, like our understanding nutrition and health and what we now understand about the microbiome and within genetics. There's a micro Buyum of Amarna and our as and motor proteins, and all sorts of other smaller actors that are causing. Downstream, whichever direction, you look that, that we hadn't occurred to us are the motivators for how things actually function. So we are as we are just scratching the surface of nutrition when it comes to the microbiome, we're just actually scratching the surface of genomics, because there's a whole bigger more complicated layer beneath just the genes themselves. And I think one of the things that because we study sex differences, Bradley one of the first questions I think it is about how do you how do you know that sex chromosomes versus hormones? So we know especially there's large differences testosterone in androgen, and estrogen progesterone. And, and so are aren't the two is completely linked together, if you're ex than you're going to have this set of hormones, and if you're way, have this in turns out that's really not true at all. And we see differences in, gene. Expression on the X Y during development the four you even have gone ads developing. So now we have this added layer where we have? Excellent, y have their own unique, gene expression than those are modulated just like everything else, Gino by Andrew Jans. Estrogens. And then there's cross talk. So it's kind of this wonderful symphony, and we just have to pick apart. You know what's the violin contributing, and what's the cello contributing, and where the Tiffany, drums, right? Like where are all these things? And that's what we're trying to do. Now to me, that's I don't think it's that we're not finding the things we just have to listen and try to tease apart those different aspects. Do you think with the amount of variation that there is inherent in the human genome that, you know that we will eventually get beyond the single, single, gene, single variant kind of system? Do you think with bioinformatics? Are we going to be able to eventually really address like the multi multi-layered multifactorial aspect of the problem one hundred percent? I think that's where we're going now that's where the leading edge of buying for Matic's into Nomex is. Going is trying to figure out how do we look for networks of interacting genes and not even just interacting genes, but interacting Eissa forms. So interacting variants of the gene, so not into only of so for G rating different illegals, then you can have a different sets of Exxon's together. Sorry, I'm getting too complicated. But right. So how do we how do we look at the variants of the gene, had we look particularly -tations in, gene? How do they look at how those are interacting with our hormones with our environment with our nutrition with stress? It's not going to be solved in our lifetime or, or ever. I'm going to say you know what come back to me when I die and tell me if I'm wrong. But. But, but I think we're making headway on it, and we're trying to what too late. I mean, it'd be really one sided conversation. So maybe will perfected the brain in a jar stuff that we were weeks ago. And then it'll be fine, we tape and not. But we're trying to figure out into it was like I you're leaving me hanging, now we're really trying to some of the things we're working on right now is to look at not only the mutation being associated with disease phenotype, for example, one of the things looking at his liver cancer, and sex differences in liver cancer. But we're looking at. The interaction of that, gene, that eleo with other Liles. And then every possible combination of Liles. So those sets of combinations get extra nominal really fast. And it used to be impossible to do that kind of computing. But we're, we're starting to get to be there, for example at a meeting of years ago. There was a large project called the human a thousand genomes project, which eventually ended up sequencing more than two thousand people and it took, you know multiple apps. Many years and tons of compute time and Google because they could decided to redo the whole project and tell us how fast in wonderful. They did it like a month. They just redid this decade long project in the entire presentation. I'm gonna get in trouble, but the entire presentation, I'm watching this. They didn't show a single new thing. Like, look, we redid this figure from this regional Apor, and then we made this figure, and then we need this figure, then we did this and you know what I did it, you know, in my spare computing time, because I'm Google and I can and. On one hand, I had been waiting for like end. The next thing we did was. This and they may be working on that next thing. But the fact that they were able to replicate, a decade worth a work in a month was just mind. Blowing gray into will be able to. We're going to be able to, you know if we don't kill the planet or selves, I work on that. Yeah. The current next next next generation of sequencers can do the human genome product or the thousand genome project over a weekend. Science projects. The manner poor stuff loan is transforming the amount of it that we can generate. Okay. So now we've generated mountains of data. What are we doing it amounts of data? Oh my gosh. Are much data that needs to be then sorted through? And, and we have humans who are trying to employ more and more machine learning. But at this point, we are way behind the man of data we can actually generate from this, even under saying, George. I just posit all that. Let's just generate a ton of data generation from now, people will be able to mind that, like Google that and do it in a month. Let's not try now generate the data. Now, let somebody else, worry about the D apartment complex it and figuring it out and making it work with. Yes. I mean, what is where do we store it? Right. Who's gonna pay for it? So some of these big projects that are publicly available data. I haven't been able to get access to because it's just such a large amount of data. It would be like saying, I would like to fit a blue whale in my living room. Yeah. Sure. I'd like to do it, but one how under them I going to get it here. Once I get here, how many small pieces, I'm gonna chop it into till it fits in here. Is it even gonna make sense? How am I gonna put it back together and good? Lord is gonna stink. Right. Like this going to be awful for everybody. And that's almost what is like dealing with these massive data. But we couldn't generate it rent. That's one of the things we could generate the chemistry in the technologies continuing to get better. So, yes. So how do should we generate it? If we should we generate the data if we don't have the computational perches to analyze it right now. So I guess part of the part of which is like this. And we ran into this. We were talking to the, the folks that were studying, I think black holes or dark matter what they're generating tremendous amount of data that is going to be ten years of analysis after which they've all left the project moved onto something else. They, they realize we created more data than we, can, we can digest. So, so, yeah, one of the one of the ideas, I've at least been hearing about is the idea that you don't have to have the WALE in the living room that wail exists in one place, and everybody goes to this sort of cloud based like public research cloud. That's just Jain Norma's destroy stuff that people can look at things there and never have to have anything local or anything moved. Yeah. The inches working on as well as other institutes, there's NIH strides initiative where people were working on the data storage, and the data analysis side. But some of the challenges still are the cost. Right. So it's there but someone has to pay for it, and who's gonna pay for it. And even let's say I just make a copy of one of the one of the smaller data sets right now. It's gonna cost me ten thousand dollars a month, and I'd computed Amazon costs what it would cost. My lab to do the kind of work. We're doing if I paid Amazon to do it, and it about fifteen thousand dollars a month. So is not free. And I don't it's one of the things I'm actually most concerned about with my lab, going forward is the data are getting so large where is it going to be who's gonna be able to access it? Is it just gonna be big big labs in what does that mean for the future of science? I think we're coming together to try to. Find solutions. But that's, that's a concern rate now for pretty much everyone doing judo isn't also amazing that with all the advances in technology and computing power that, that's the bottleneck. That's kinda cool. The bottleneck is actually information storage and handling. That is, that's an incredible place to have pushed the bottleneck to and our ability to view the guy. Yeah, I dunno ironic. But maybe Iranian Jason. Yeah. I would say, another bottleneck though is, is training students. So the students in computation like computer science fields don't have enough of the biology, background the assumptions are, and students in biology are still not to digitally trained in in computing. And so it's one of the things we're working on that. It's been kind of my, my pet project benefit for it over the next few years how to heavily as a community. There's a lot of people that are working on it. Right. I could list of people that are working on that. But how can we integrate better so that it's not black boxes 'cause they can't ever be black boxes. I mean, they will be to some people, but how do we get students especially students have been underrepresented science who haven't been able to ask their questions. Right. That's the one other thing if I could jab it in there, is that in sex differences research most of the questions have been asked by only one sex. And that limits, the questions that are asked almost all the clinical research, that's been done has been done in a European males, and that limits, the kinds of things we can ask in the questions we can ask of also Tillery of the results into one of the things we're really trying to do ASU. I drank the issue Kool-Aid on. It's who we include on her. We exclude that we pride ourselves on an end to do that. We actually have to develop these training because the questions I think about in that I'm interested in are very different than the people who are in my field, who admire but are thirty years my senior, and they're very different than the people that I'm training. And so, that's, that's the thing that I would like to see us as a community work forward. To have more open source, free trainings in computational life sciences. And that's the nice thing about genomics field. Like we have we've accomplished sticklers, but we're we're we're pretty good. Okay. Yeah. We have some. Ails. To be done. We're done. We're working on it. Right. Like, and there's enough of us that are like you know what I would rather have a great, I would rather science a great place, then not. And I'm willing to put in the time in effort and give up something because of that. And so I'm hoping that those was his will continue to, I wonder how we, we've talked with people in the DIY bio, that kind of biohacking community, where people are starting wet labs in garages, or creating office spaces that our community communal research spaces and that's happening for biology in general for, you know, people are starting to use crisper in a. In their garages, and in their kitchens. But I wonder if this open training for computational, biosciences could also be implemented someway in this, you know, DIY fashion. I love to see that. And I mean, there are some really great resources are ready. I just. So it's not that the some of the resources don't cyst but how do we convince? Middle school and high school and college students that this is the that you will be able to cool science using your computer and not just in the wetland. That's right. That the little bit of it. But I think we are getting the I do I got DIY bio is to cook. I Christopher my dog look alike. I'm not going to but, but you yeah. How we generate all the data in the world like we can now? It's amazing. And we can do this science. We just wanna make sure everybody can't, I think I think there's, there's a lot of potential out there, considering that computer literacy is the baseline of just life now. And I think that there was there was a lot of barriers especially women participating in computer science in the past felt like a male dominated field, not for women. I don't feel like that's so much the case anymore. Not nearly as much we've talked about it on the show. Right. That the, the, the scales are getting closer to balance there. And I think that, you know, we are starting to see a change in science as well. I hope it happens fast, but it would be great if both of these areas, are starting to see equal participation, not just gender-based, but also omic status ethnicity. All. These different things. But then the idea that they would work together is really exciting. It is. But this is the other side of this, though. I mean is I've seen the, the lifelong biologist biology enthusiast who's turned into a screen time, Kotor going, I love what I do. But I'm in front of a screen all day, instead about nature, which is what I got me into this in the first place. And then I've also seen the coders who like I'm having to learn all of this, biological stuff that makes me uncomfortable. But. Yeah. Computers are huge part of every job. Now I mean, I got started because I love animals, and I spend most days, most of the time in front of a computer. I feel like that's just the way that the world is going. And there's very little to change that. And by for Matic's I mean, honestly kids, there are jobs there in the future. So many jobs. But I, I. The point of thinking about are the the number one rule. I tell everyone they come into my lab is that they're, they're physical and mental health before anything else, and that's that is thing like, we have to also make sure that we're not just sitting all of the time that we do get out. We do interact. We go outside the, we see the biology that we're working on hopefully preserve it in. I don't I'm not very good at that myself. So as I do by. But I think that's also an important thing in science. Absolutely four. Getting back to the gamma coming to the end of a of our time with you here and I would love to know what you think as, as from your research, and what you're working on what are the what are the big questions that are outstanding for you in, in what you do. So the biggest question that we actually have a paper coming out in a couple of weeks on is a why are there, consistent sex differences in certain diseases? So why do women get autoimmune diseases at rates much higher than men? So, for example, rheumatoid arthritis. Women are diagnosed with are a rheumatoid arthritis eight times, more often than or what. And nearly all on diseases show. A female bias on the flipside, nearly all cancers all non reproductive cancers nearly all non reproductive cancer show, a male bias in incidents that is females get less cancer than than males and we've been we've been working on a theory to try to explain this, but we're gonna have to spend the next. I mean, the rest of my career to try to figure out. This is true thinking about how. So if the immune system is so critical for many things for helping us by diseases. We know immuno therapies are becoming really popular an and beneficial in treating cancers. So if for some reason, women, the immune system is prone to being overactive, and pleading to auto immune diseases, it could be that is not that men are getting more cancer. But that women are getting less because on average their immune systems are slightly a reacted, and so then he would say, well, why that explains the autoimmune prevalence also it, but then we're trying to think about. So, what's, what's the reason for that right, wise there, this, this large difference in one of the things? So have you talked about the hygiene, hypothesis or later? Later on the show stories in the second half of the show. Okay. Can I can I? Is that between a for almost all of human history, rightly, exposed to parasites and pathogens that we didn't have antibiotics we don't wash their hands and that in industrialized societies? We have access to, to soap water clean. Clean lives in sanitation. And, and so that can explain why nearly everyone is more prone in industrial societies to getting as analogy springs. The immune system is primed for all of human history for everybody to be exposed to pathogens, but it doesn't explain the sex difference. So the other thing that we think is different is that for nearly all of human history, there was no contraception you from the time you were reproductively active you're pregnant or lactating until you couldn't anymore. This is our Papa. So the union system in people who could get pregnant had to be primed because there's cool. Thanks. The placenta itself actually blurbs off these little signals. It's trying to down regulate the maternal mutant system, because maternal immune system is saying, hey, right. Yeah, not so not so parasites the rid of it. But in ex- ex- individuals who have cool genetic ex- ex- mechanism. They have to not just down regulate. But they have to compensate in particular ways, because you have to tolerate this genetically distinct individual trying to down regulate your immune system and also not dia- parasites and pathogens. Don't die. That's the goal don't die. And now in modern industrial society. You're not pregnant or laughing for your entire reproductive career. And so could that the new system is primed to be up regulated in certain ways, which is why not all auto immune diseases show, the same sex difference, but agree prime to be up regulated. But it's not all bad news. Because maybe it's leading to those reduced rates of cancer. If we could explain why they're these big sex differences in this is it than it could help us nail down the mechanism. Right. We're not saying should be barefoot impregnable life. No, we're saying. We should figure out what parts of the union system are the ones that are causing the sex differences, then we can target those, we can explain why women are responding better to immunotherapy than men could explain why they're getting less cancer with explain banner getting less auto immune disease and could target their appease. So we just got self human health. Kidding question. It's amazing. All right. Well, I won't keep you any longer, I would love to know where people can find you online, if they're interested in finding out more about your research, or following your social media, and Asian work. Yeah. Has sex Chr chromosomes affects chromosome blab. Is that weight? Chr lab, either at at six chromosome lab on Twitter or system lab or or. Those are probably the two easiest places I do respond to people, I blow I used to blog all the time before I had that monster. That's running around. And that's math bio nerd, so. Oh, yeah. So, yeah. On the main page, it has Twitter handle and Email. And I'm I'm super happy to talk with people. Sometimes I'm very slow responding. But, but I will. Fantastic. Thank you so much for joining us tonight. It has been just wonderful to get to. I was gonna hang around. But I'm going to wrangle some of Tamaz, Raymond. Some, some child energy need. Yes. Again. Have a wonderful night, and I will be in touch later. Yeah. Thank you very much. Ninety two. I hope that we can have her back on the show again at some point because that was an interview that probably could have gone on much. Conversation. I told Blair before the before the show started, as I said, I think she's my new favorite. Oh, careful. Kiki other here you. No. What? I don't think I remember an interview that was by itself, seeming like in introduction to all of the things we could be talking about the entire way through, and like an hour. So that's, that's a lot. That's deep. Yeah. We didn't get to talk about my color, blindness. We didn't get to talk of sex linked traits. I get to talk about temperature dependent sex determination. Inactivation. Par. And this is I know we really did. There's lots more to discuss there is. So maybe we will be able to get her back on the show. I get another time if you out there like what you heard and wanna hear again, let us know. And let us know if we should get in touch with Dr Wilson for another interview sometime down the road to talk more about sex and biology because this is interesting stuff. We have come to the end of the first half of our show. We're gonna take a short break, and we'll be back in the second half. With more of that hygiene, hypothesis stuff, we're going to be talking about that. We've got we're going to be dropping some coral and then there's got fish gins because fish skins. Yep. This is this week in science. Stay tuned. For more coming right up? Thank you for listening to this episode of twists. We would love to invite you to Santa Fe with us come to Santa Fe. Are you in Santa Fe, are you in Albuquerque New Mexico? Come to the interplanetary festival, which is organized by the Santa Fe institute taking place, the weekend of June, fifteenth and sixteenth. We will be podcasting live from Santa Fe interplanetary festival on June. 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It'll take you to YouTube, I tunes or Google play podcast portal to subscribe, if you're looking for another location, you might try searching, your favorite browser. If search engine also you can send anyone who is not subscribed to twist to twist dot org to let them click on that subscribe button and join us weekly get twists in their inboxes every single week. Oh, the science more science. More science more science. And it's all because of you. Yes. All of you help us do what we do listening. Bring us what assigns done for you lately, and all sorts of fun, recommendations for interviews telling us how it is. And you listen and this is for you, and it's all about you really. We couldn't do it without you. Thank you for your support. And we're back with more this week in science. Yes, we are. And it's time now for this week in what has science done for me. Everyone channel. Well, yeah. Channel your energy in it. Our letter this week comes to us from Joyce berkers. She writes. Hi, all I got turned onto twists in my undergrad as a biochemistry student hearing, my professor mentioned this week in virology. I think it was. That's another very good podcast. And so, I went looking for the broader science version, now nearly six years later through teaching ESL anti wan two years of teachers college and moving to England to teach secondary. School science listening to twist on long walks or trips as the one constant that has stuck with me listening to a recent episode something clicked into my in my brain as to what twists had done for me this past year. The school in teaching in has had a large turnover of science teachers over the past couple of years. So when I arrived in September most of the science lessons most of my students had received had been delivered by non science specialists who didn't have the same passion for science as their own subjects. This had led my students being highly unenthusiastic about their science lessons. Very closed minded about science potentially being any fun through September and October. Getting the students to engage with the lesson was like trying to pull my own teeth out. I can't do this. I'm no good at science anyway. There's no point of trying things I would hear every day I could see why a lot of their teachers had left after short periods of time. It was taking my excitement for science with it. However, I had a half hour walk to school, every morning during which I would listen to twists. And here's some exciting thing happening in science I had a bit of backing backlog, worked backlog to work through. So it was never ending stream for me. This meant that every day. I would have some new cool science thing to hold onto, and keep that ember of science joy alive in my soul just before Christmas. I realized that my toughest group of students were no longer the dread of. My day because they were hopping onto the science train joying the experiments and making connections between what we were learning in class and the world around them in February. I had a Sturt had a student comment, miss your brain is so full of science, isn't it? I bet if your head exploded all kinds of science stuff would come out. Last last month. I had a student, tell me boring organic chemistry was fun, after being told that a lot of people struggle with it because they find it's less interesting than other topics. And finally just today I had a student ask me, miss, do you think I could be a person who does science when they grow up? Oh, yes, listening to twist has kept my passion for science alive through some really rough days. And it has allowed me to spread it onto a new generation of students who may otherwise of fallen through the cracks and would never have known all the things science does for them every day. Thank you for teaching. Thank you for being a, a font of scientific knowledge with a head. So full of science would come exploding out of your your head. Oh, thank you so much of a writing this letter Joyce. I really appreciate receiving it. We're so glad to have you in our audience and listening to twists along with us. Thank you. And remember everyone if you would like to write in a song a letter a note, a sonnet you can send me an Email. Kirstin K, I, R, S, T, E N at this week, insci- dot com or leave a message on our Facebook page, that's Facebook dot com slash this week in science. All right. Let's get onto that science that we keep talking about speaking of the hygiene, hypothesis. It's like she, it's like she knew. Researchers just published in the journal psychopharmacology and you might be going psychopharmacology and hygiene hypothesis. Would those things have in common? Why do they go together? Well, so as Dr Wilson explained in the first half of the show, the hygiene, hypothesis is this idea that we're in this modern sterile environment, and our immune system is looking for something to react to right at wants to keep us safe, but we just don't have anything there. Well, there is a researcher at the university of Colorado boulder. He and his team have been working on this idea of the hygiene, hypothesis and looking at they've done work that we've reported on through the years related to finding that people who live in rural environments, if they work among livestock, or around animals that they seem to have. Have. Less allergies, asthma and other people, and it backs up this hygiene, hypothesis, and the other I other ideas have also gotten into even further the idea that there are microbes in the soil that are very involved in this allergic, or lack of allergic, or asthma response. But Dr Lowry from university of Colorado boulder, he and his team, they're thinking that maybe it shouldn't be called the hygiene hypothesis anymore, and that maybe we should refer to these microbes in the soil as old friends. We should be changing the idea to. It's not that our body is constantly looking for the bad bacteria to fight off. But maybe there are also beneficial bacteria that enable us to be healthier, that through their own actions and interactions with our physio legiti. They help us be better. And so lower had had previously published a paper in the proceedings of the National Academy of sciences, looking at a bacterium called Mycobacterium, vac say, and this bookie. Yes. Vecchi. Vac. Okay. And this is a soil bacteria found in the dirt. They found that if they injected this bacterium into mice, they could fend off. PTSD like sin symptoms. A syndrome after a stressful event. So prior to the event, the injected the bacterium into the animals, and then stressed them out that the animals were more able to deal with the stressful event, and they were less anxious and stressed out, and they didn't get the PTSD. And so these researchers like whoa, this bacterium is blocking this anxiety fear response. How is it doing that? And this new paper. Talks about a novel lipid that they have discovered fatty acid called ten z. Hex adecco. No IQ acid and it's used and it's inside the cells. It's it acts like a key in a lock. It binds to specific receptors. They're called paroxysm proliferator-activated receptors p p R, and these inhibit inflammatory pathways, so they inhibit the bodies inflammation response. And so the bacteria, it seems Lowry says that these bacteria, we co evolved with have the trick up their sleeve when taken up by immune cells. They release these lipids that bind to the receptor and shut off the inflammable in inflammation cascade. And so, would he's thinking is that maybe we could develop a stress vaccine from these bacteria that could be given to people in high stress jobs that would help them to not get things like this PTSD type symptoms. So, so we, we get a stress vaccine from the Micromax him vaca-, which which would make it a double Latin root for cows and the cows part of the story cows are not fighting. This bacterium is probably found in the soil where cows live. The researchers also think this is just one species of one type of bacterium that is in the soil. But there are all sorts of others millions of other strains. And in terms of identifying the mechanisms through which they have evolved, we have evolved with them to be healthy. They're potentially a lot of places that we can be looking for this kind of. Mental health health, so, okay. So just in as we have talked about discovering nutrition has this gigantic microbiome element to it, that cognition health. Dna expression, microbiome plays a role in all of these things. Why should it be surprising that the entire rest of our environment, externally is not also contributing interacting playing on and being part of human health for the millions of years? That was our external microbiome. I think the idea is not it's not that it's new, it's just becoming more nuanced. So the hygiene, hypothesis came about in the eighties, but it it's thinking of us responding to the bad environment where responding to the stressors or responding to the bad things that are coming to attack us, as opposed to this more nuanced idea that yeah. There, probably there are parasites. There are bad things out there that are infecting us and doing damage, but there are a lot of good things as well. And so we have to have a much more, I think it's maybe not nuanced, maybe that's the wrong route, but more holistic in it's our understanding of the environment, influence our in influences our entire physiology. There's an external probiotics that that has been overlooked as at just as the internal probiotic has been overlooked. And I think essentially at the. End of the day, we will find that. The majority, I won't say vast majority because there's not very, many majorities that are best. But the majority of microbial interactions over the Aleutian of life on this planet are positive. That's why we're live. And that's why they're there. And that's why this interaction has gone on as long as it has the outliers that have the negative affect. And, and so when you eliminate and internal if you take antibiotics every day, you will die. So it shouldn't be surprising that if you try to over. Sterilize your environment. You will also encounter negative health effects. It's this is this is where we found a healthy balance on band is relying. Not just not just like tolerating or being able to handle the exposure to but actually relying on input from internal external microbes for our health as resources. Yeah. I think it's an interest, it's just kind of looking at it from a different direction. So you know, as opposed to saying that will some stress is actually good for you saying, it's, you know, if you don't have any bacteria to fight. Your body has bad responses said you're saying, actually, there's good stuff going on. That's getting missed out a picture, so many years ago, we talked about a story from some scared in even country. I do not recall which I want to Sweden, but they talked about how, how cut will, I guess, not Scandinavian, but anyway, it was a country where they did a study on houses with dishwashers. And they said that houses with dishwashers at higher rates of allergies. And so the implication, there was that by removing the potential allergens in such a perfect kind of hermetically sealed way they were not expose. And therefore they had higher allergies. But what if according to this instead of just being exposed to the allergens, you're actually missing out on an important part of your micro bio that is on those dishes right in it's possible. Yeah. And so what this guy wants he prefers calling it the old friends hypothesis as opposed to the hygiene, hypothesis. And I think that may they may be complementary hypotheses, not necessarily that they that they cancel each other out, but yeah. So anyway, old friends, we've got our old friends, and then my, my other cool story had to do, again, much, much in line with our interview from earlier. Researchers have been looking at from the Donnelley's center in Toronto have been looking at genes and how they are similar. Our across organisms. And they found that dozens of genes that were thought to have similar roles are, in fact, unique to humans and might explain our origins, or at least the origins of all of our amazing abilities, like cognition whatnot. So these genes are transcription factors. They are code for these factors that usually are short sequences of our nature that go out and control other genes. So turn genes up, turn them off, and they're these control factors. Transcription factors is transferred. Krant transcription factors when they're coming. To a segment of DNA, and they're going to bind to it to turn it on or turn, it off or do regulated in the way that they will they recognize something that's called a motif. It's a little part of the DNA code, that's part of gene, and it's this little identification factor. And these motifs are used as they're like the landing sites. It's got the, the this area of DNA DNA, that's like you come in here land. Let's do the transcription. Researchers had just kind of looked at these motifs gal. There's similar they've got they start with the same things and the kinda end with the same things they're similar enough. They probably do the same thing. And so these transcription factors all we're gonna lump them together. And they all do the same thing, what this study shows that that's not really how it works publishing a Nature Genetics. The researchers have looked at these transcription motifs from with new computational method. And they have been predicting even more accurately, how transcription factors bind in different species, and what they've, they're what they found really that there are. Sub classes of transcription factors that might do one kind of regulation. But there are these parts of the motifs that they are highly sensitive to which make them it's having a more specialized lock and key situation so instead of maybe having recognizing one particular puzzle piece, it's no it's different puzzle piece. And so the researchers say even between closely related species, there's a non Neg negligible. Portion means it's there's a lot of them of transcription factors that are likely to bind to new sequences. This means they're likely to have novel functions by regulating, different genes, which may be important for species differences in so chimps and humans were ninety nine percent identical in our genomes, but there are lots and lots of these transcription. Factors, which vary in what they recognize which motifs they recognize between the two species. So even though chimps and humans might have the same transcription factors. Apparently from the outside the way that we had been looking at it now with our finer tooth comb, realizing that they're not actually regulating the same jeans the met, regulating the same and also the bulk of the genetics that when we say that ninety nine percent. Yeah. So much of genetic code is just like cell function like basic self basic like so much of it is this regulation. It's what turned on in which turned off. And so I think understanding this is like a huge deal of absolute. Yeah. There anyway. Finer tuned, control of these motifs in these transcription factors is by is, is important for the binding and the function of which genes get turned on turned off and how species maybe find our differences. Tell me a story, Justin. Right. Let's see. Coral reefs the thing that we talk about on this show. And if you've been paying attention, if you already know that half the planet's oxygen is produced by the corals, and that coral reefs are in serious jeopardy of declined via climate change aka climb Michio, and things may be much worse than we imagined. New study published in nature climate change finds coral reefs are also under threat from ocean acidification, of course. But the results some crows in curling algae chronology being algae, described, here's glue. It is holding coral reefs together cannot survive the expected acid ocean acidification caused by climate change. This is quoting voice, Steve O'Malley, who is now basing sober university say CNRS laboratory the Fe. Bill say somewhere in France. The results validate previous research on oceans, vacation threats. Go. Reefs. This is also co author professor, Malcolm macculloch commuter receive Western Australia, infects on the Kaos effecting fluid, we're rapid and persisted for the whole year, basically declines in Coralline algae. That's we stuff could lead to the loss of important marine species that use the owl, Judy as a nursery. They did find a few of the reef corals that could survive and acid affiliation event. But they also discovered that those we're already. Basically set up to survive. They were already resistant to it. This was not an adaptation. They found zero adaptation to acidification. Which means that we reefs that are even available in highly divide. Ocean are going to be extremely limited, and may not be anything close to what we currently consider a reef system. So there's a couple of things here, one is, you can take some, some things from these coral that we've identified that are already set up to be resistant to waters, and you can use crisper and isolate those things and put them into other species, or you could just use those coral species, and try to breed them and adapt them to different temperatures and try to put them into these other reef ecosystems. But ultimately, I think the thing about ocean is vacation that people get kind of focused on is, is kind of just looking at this one thing. But you have ocean acidification happening. And you have ocean warming happening, and you have sea-level rise happening and you have pollution, and you have reduction of species, happening, all at once, and I think that is the thing that we need to keep in mind is that there's all there's this perfect storm brewing. And if we can reduce any of those factors, there's a better chance of species, making it through the other stressors involved to your point of using something like crisper genetic alteration that sort of scenario, it would then be much easier for us to focus on genetically during the next generation of humans to live without oxygen. Just have one species. We might have a tough time with a with, you know, just like basic H EP. Tom. Turn on the gills, you'd really have to start. It's where what, so that's also jn though, remember. Yeah. So oxyde oxygenation is still important. Couple of steps. Yeah. This though. I think it's very interesting to think, you know, if if there's no acclimatization within one year, you know, how many will survive till the second year and will there ever be acclimatization will there be app. Tation. Is it within the ability? I mean if you don't see it in one year. Does that what does that mean? Or if it's basically, is it suggestive that if it's just not it's not in this species. But it's, it's more likely to happen. If you reduce some of the stress factors just kind of what I was talking about before rain. So if you if you have everything attacking these Reese, all at once there is a lot less chance for them to adapt and grow and be able to survive. So that's one of the reasons why, for example, marine, protected areas are so important, because you can reduce fishing and human disruption in an area. There's a better chance. They can find solutions to ocean acidification or sea level rise or rising sea chapters. So the other thing I would throw out there is, is if you look back at Evelyn bottlenecks. There is some level of adept nation that we see, but much more often we see niche filling after the fact about on where something expands its ranger things move into territory. That was a niche resource. That was traditionally a previously occupied by some other life form. And that sort of evolutionary niche, filling that would take place over millions of years, perhaps, we'll come long after all, humans are got just say people on this is there's a pace in a rate of timeframe in which these things take place. That is not beneficial. It's like we've discussed before the earth's not going to end. But it might not be so fun to be here. You know why I'm glad here too. I'm glad to be here right now. Why because it's time for Blair's animal corner. Animal. Except more giant. I have a story about some horn Greb. Let's all agree. What do you think corn green beans? Really, because you to not hang. No, there's no anger in. There are horn more. So this is. A story about Egyptian fruit bats, and a very interesting arrangement that males and females have made. So the story, yes, as this story coming from Tel Aviv, university university, looking at the very particular interaction that happens chain males and females. They looked at three captive back colonies over the course of a year, and they looked they watched as males would collect food. They would go back into the cave where all the bats were, and then the females would stay steal food from the male's right out of their mouths. Why do the males allow this turns out? The males are often paid back. How you ask. I can guess. Yeah, you're exactly right. It's the civically the kind of sex that leads to offspring. Yes. So there is a strong relationship between producers scrounge feeding interactions and reproduction. Females bore pups of the males. They scrounged food from so, again, three bat colonies over the course of the year in so they kind of watched they had a bunch of different potential hypotheses. They thought maybe it was relative related or that there was just so, so high cost to defending your food resources, the ladies would beat them up so badly that it wouldn't be worth it. But no, no, it looks like it's all about sex. So they did that is by watching the bats, but also determining paternity that were born in the colony females gave birth to young males from, which they had scrounged food. Pretty consistently so the not only were they having sex, but their babies were from these males that they took food from out of their mouth. There was almost no overlap between males preferred by each female also so each female had her food. Bet was also her boyfriend. And so this looks like the females have specific males that they picked to scrounge from based on individual preference. That next part is the thing, we don't know anything about what the individual preference may be if it's luck of the draw is just it's easier to go after the same guile time who knows especially because those personal preferences change from year to year. So I'm still. That happened in the first two or three sentences of the story where you pointed it was. The type of sex that specifically three production because I didn't know that bats engaged in type of sex Notley the reproduction. Animals. Tricky stuff going on. Okay. It could be sperm storage. There could be sperm competition. There could be just termination of pregnancy. There's so much stuff going on that it doesn't always lead that way. Also, it might be possible. Females feeding multiple males and not all of the males ended up fathering offspring. Right. But in this case, they picked one male they went with him. And that was the father of their babies. I find it interesting because there are many species of animals that give food offerings as part of a courtship ritual. So look at what a good provider I am. And so in a sense, this is of female taking taking that resource and saying, you are a good provider. We've traded food, and now we will have this relationship. Yes. Because because a bat colony. So like. And when just fly out tens of thousands of bats, and then they go back and that you're finding the one mate and that crowd, right? Really? Well, what, what they say, that's thank all humans look, so. Monogamy thing bats. It's all how do you, not somebody? Seasonal monogamy. So it's only for the season so they have a new mate every single year. But yes, there is a consistency there. The the next step kind of this study for this team. They want to see how these relationships evolve change are established over long periods of time. So that's kind of key what you were getting to is this demonstration to say? Hey, will you go steady with me? Or is this something that the females just try to steal food for a bunch of different males than they try to, they find on finally who concedes, what who is the aggressor? How is this being addressed? Does that behavior escalate overtime? Is there a variance in how often they bring them food and how often they eat the their own food? Is that a decision that the male makes there's lots of choir? Your is a male this male may selection by whether or not the food in them out. Waiting. I love this that hawks male hawks are waste smaller than female hawks fan and they will bring kill to a female and kind of drop at nearby and then run away and get back behind and go do you like that? If the fever likes it, they're like, okay. Okay. Okay. Can I come a little bit close? How about if I come a little bit. Okay. So they're very they bring a president. That's very clearly. They're bringing the female a present. And they're saying, will you tolerate my presence. So. Yeah. Is this that or is the male, tolerating the female stealing the food? So there's this huge lots and lots of questions to be asked. But in the meantime, some very clear food for sex transactional, behavior happening with pets. All right. What's up with fish skin? Oh my goodness. So this is an anecdotal piece of science news, alert, alert, alert, anecdotal knowing outing of data here as story is his story. But it leads to a lot of interesting questions. And so I thought it was worth discussing. So this is from Michigan State University veterinary medical center. This is a one year old female Rottweiler named Stella. She was caught in a house fire in Lansing Michigan while her owners were away. She is scape the house, but not until she acquired burns across her head nose ear hind end and sides per body. They were a lot of them were second and third degree burns, ten percent of her body was covered in second and third degree burns, and she had severe smoke inhalation in respiratory problems. She also developed ulcers scarring in both is because a fire exposure epidemic. Epidemic. She no kidding. She's not right. And and seem. So you could see how this is looking dire for Sela. But spoiler alert, she did survive. So the Michigan State University veterinary medical center jumped in to help her and the initial threat was the injuries are tricky, and lungs from smoke inhalation and scarring burning there. So she put was put on Ivy. She was given pure oxygen up the nose in when she stabilized. They had to address these second third degree burns, soft tissue surgery. They could not anesthetize her because of her respiratory injuries. You need to be able to put an animal on. On a respirator in order to do anesthesia. And so also slowing her heart rate was a concern for a bunch of reasons, so they couldn't put her out so they couldn't do traditional skin, graphs. So they tried something new. They used Icelandic de scaled codfish skin. Yes. And they grafted that to the second third degree burns on her body. The tissue of this codfish skin has high mega three fatty acids. And so they naturally are anti inflammatory antibiotic all good stuff, so they could do these skin, graphs without heavy sedation. And this is where it gets absolutely in the DC, scaled skin is what makes it from other fish crafts. Which apparently, there are other fish, graphs that are done in veterinary medicine, which I didn't even realize to Latvia. So they'll use scale to lappy graphs, which during the California wildfires. Apparently they used on a bunch of pets. They're affected, but basically, it's just organic covering. It's like an organic band-aid while the skin underneath heels, but the DC scaled graphs. They stimulated the production of cells and ended up becoming functional living tissue in stella's case these graphs. They can they can change them out. But eventually these these graphs were absorbed by her body and Nutricia tissue grew into the graft. It created a scaffold. Yeah. Grow into. Yeah. Yeah. Scales. No scales. So just to give you an update on where still is that she still has respiratory problems. She'll mostly have to be monitored for the rest of her life, but she is otherwise doing great. She's resting at home. The skin graphs have taken all of it is sounded good. And so this is going to be presented at the society of veterinary soft tissue surgery convention in June. So they're going to discuss the applications of these scales fish, graphs in the veterinary medical field at a larger scale. And so that's very interesting. But also that I can't help but wonder how come nobody's talking about humans with this. Like I'm part fish now donate. Yeah. I mean, maybe because. Maybe we have skin donors. Maybe there are other situations available and who knows. Maybe we just aren't aware of this scale fish skin in use new human. Let's come from, or, or this is something that is currently being I tested in animals. And then we instant humans potential, but this is pretty cool. Yeah, Jerry, cool. Yeah. And I'll just give you this last little uplifting note, this is what the head of surgeons said about Sela Stella, she's a living example, that the fire within her for stronger than the fire that injured her. Oh. Yeah. She was a fighter but that skin graft that fish skin graft really did it. All right. We are at the quick stories part of the show, and I would love to tell you a couple stories about planets. That's right. So eighteen more Exo planets have been discovered in the Kepler data. This is very exciting. Researchers said, hey, let's look at this in a different way. And so they've discovered in our in our Milky Way. Galaxy eighteen more Exo planets one of which is. Bigger than the earth, but in a habitable zone where it could actually have liquid water. It's called epic. Two to two thousand twelve three eight one one zero point zero two but I'll just call it. Okay. Did a twelve year old boy named that plan? Possibly. That turned into a scientist. Shea the new technique that they have used they will be applying to more of the Kepler data. They haven't looked at all the Kepler data yet. So more Exo planet may be in the findings and then another planet found by a different planet survey called the next generation transient survey. This is a is located at the European southern observatory Paranal. Observatory at the Atacama desert in Chile, and this observatory its ground-based is not in space, Kepler. It's on the ground and so ground based stuff. We know we're like, hey, what can you actually see, but this ground ground-based transit survey. Looking at planets transiting their stars has found a nip Neptune sized planet in very close to the host star. What should be called? And researchers calling it a neptunium desert, the ideas that you shouldn't find big big hot Neptune sized planets really close into the star. But that's what they found this planet. N G, T S, four B is twenty percent smaller than Neptune. It's about only three times the size of earth, and it's been nicknamed the forbidden planet because it's not supposed to be where it is. It's hotter than mercury thousand degrees celsius and it orbits at star something like every one point three days. So it's just zipping around. It starts a k type star this, the last piece of information about this is that researchers think that this Neptune ish planet, gassy planet, it still has gas around it, and it's close into the star win. It should be radiated and have lost its atmosphere already which suggests it either is for some reason, really. Really strong able to withstand solar radiation, that would irradiate the atmosphere or it probably migrated from somewhere further out in its solar system to the place where it is close to the star. So researchers are looking into why exactly it's there but they're gonna look for more planets in the Neptune desert. Yep. More stories. Yeah, I have one more animal story for you. It's kind of terrifying. Chimpanzees have been spotted in a particular space in long ago, national park in Gabon. They have been spotted cracking open tortoises. They crack against the crack the giant tortoises against tree trunks, and then just crack open at half and scoop out the meat. Tortoises and chimpanzees. Coexist elsewhere, and other primates are known to feed on young soft tortoises, but nobody's ever seen these animals, eating full grown adult hard shelled tortoises. So this is totally unusual. Interestingly, the same park also has hard shelled fruit that needs to be whacked against a tree to open it. Which means a lot of the researchers discovered this think that that was actually the kind of start of this behavior. Which means this is a particular chimpanzee society that does this no other chimpanzee groups can do are these also the chimpanzees crabs because there's a story. Because there's a stray, I'd, it's not something I brought, but they were talking about that were cracking open and eating crap. I think cracking open crabs is. Easier than cracking open. Tortoise either fused bones. So this is way harder grounding path of smacking stuff open to that. What's on the inside? You could really just if you wanted you just crap crack it in either hand but this is really difficult end. In fact, they even saw weaker chimpanzees passing. Tortoise to a stronger dolt to wack it open for them. So this is the idea that there is some sort of particular culture of chimpanzees that are doing this, which is a reminder that as chimpanzee populations in Africa are disappearing due to habitat destruction poaching that you can't just take chimps run other area breed them and put them back in and get the same functional. Ecological impact as the original society of chimpanzees because if they have a particular skill set that they're passing down that could be lost, which is a good reminder. Justin. You wanna talk about knee Anders? This university, France. Did yarn? I'm just guessing published in the open access journal looked at the NFL's and Serra filing hypothesis. That. The mandatory got bred out of existence. And there is the, the idea that there was a reduction in sort of Tilleke that propagated once they started interacting with current modern human out of Africa. And what they discovered is that they had they created a couple models, basically, they found that if you were -duced the Nando for Chile rates. Women by two point seven percent. That would be enough to make them extinct in ten thousand years, which fits within the fourteen thousand year frame in which they were sort of here present in four on the call form and indistinguishable beyond some small percentage in twenty three in me genetic survey, if they reduced the fertility by eight percent, it hit the low end of four thousand years, and we have found some evidence within the inherited traits of modern current humans that for Tilleke related genetic. Markers that, that are that lead to reduced for Tilleke are, are traceable back to the NFL. Origins that it's a pretty decent explanation, perhaps of how they were out competed. Just normal everyday sex. That that makes us come full circle on our of sex. Episode full closure full circle. Thank you for listening. My goodness. 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Way Better Sex Without the Pill Dr. Jolene Brighten : 617
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Dot com slash dave free all one word you'll automatically get access to your unique coupon code to claim your free bottle one per household limit lease. It's ballot while supplies last it stays with high performance your listening to bulletproof radio with dave asprey today's cool factor the day is is it. The birth control pill impairs women's emotion recognition. New research suggests that women who use oral hormonal contraceptives are less able to recognize facial expressions of complex emotions now in the better baby book my first book going back to twenty eleven. I wrote about out some very unfortunate side effects of oral contraceptives. Basically your hormones are a delegate system that can be easily broken and with all sorts of unintended side effects in fact some studies have suggested there's an association between taking the pill having mood swings and increased risk of depression russian and this new research says that impaired social judgments is another adverse psychological effect to the real benefits of birth control. Birth control is quite liberating and really useful. There are just different ways to do with it might not affect your psychology. According to this new study women who take the pill or less likely to identify fight complex emotional expressions like pride or contempt accurately and those differences in emotion recognition did not depend on women's menstrual joel cycle phase at all and finding now suggests that oral contraceptives should come with a warning label that say hey these could affect your ability to perceive and interpret emotions from others today and this was just published in medical news today and this came out of research group in germany that was published in the frontiers neuro science. You've heard me talk a lot about mico qendra power houses of your cells. They're important because they make the energy that fuels everything you do your mitochondria. No country are under a lot of stress from a bunch of different things in the environment but you can hack them. What are the best ways to do that is with a light therapy device. Ideally something that can treat your entire body something something like a jew. That's j. o. v. I love my full body. Juve and i wrote about how it helps me sleep in my new book game changers in the book i talk about artificial blue light from screens keeps you up at night natural red and near infrared light does the opposite it boosts melatonin production helps to reset your circadian rhythm and since i started using using the juve. I've never slept better other reasons. I like it are some manufacturers aren't as transparent with power measurements but the new design is f._d._a. Cleared an independently third party tested for therapeutic out but and they've got a modular design which means you can build a full body system over time and totally customize it to your space and treatment knees. I i like the mobile stand but you can do door mounting as well lastly there launching new hand-held device called the juve go. That's great travel. It's a bit larger than an iphone but it delivers the the same therapeutic power as full body systems and is wireless and rechargeable good do dot com slash dave and check out the tubes. That's j. o. V. dot com slash. Dave use that u._r._l. And the team is giving away a copy of my new book game changers for every bulletproof listener who purchases a device happy driven now. Today's guest is definitely going to talk about hormones not necessarily just birth control. Although i'm sure we're going to touch on it because i'm welcoming dr jill lean brighton back to bulletproof radio today. She's a functional naturopathic medical doctor and intro biochemist and she really digs deep on women's mints and the clinton health she was last episode four hundred fifty in about a couple hundred episodes ago about how hormones affect all parts of people's bodies and brains at different the ages and stages of life and they were going to go in a little bit of a different direction because we're gonna talk about something called post birth control syndrome and the long term affects of hormonal contraceptives and that's in part because jillian just came out with a new book called beyond beyond the pill a thirty day plan to support women on birth control help them transition off and eliminate symptoms of post birth control syndrome now. You may be listening going. Emma dude not my deal. Here's the deal you probably have women in your life and i am fully convinced that the side effects of the way we're doing <hes> contraception. Today are much much larger than is than than is necessary and that if we acknowledge these things we can improve the ah the quality of life emotional life physical health and all sorts of things for about fifty one percent of the global population joelene. Welcome back to the show. Oh hey there. Thanks so much for having me and i wanna say if you are dude you wanna listening because birth control is impacting your mate selection in fact. There's been research to show that strippers or exotic dancers not sure the p._c. Term i've been googling. This haven't figured it out yet but they want to do that. I prefer to call myself suffo- professional dancer probably professional dancer no judging if this is what you do in your for your profession but the interesting yeah just on on weekends. Don's bulletproof keeps going right you. I'm like i just see pasties. That's a bulletproof and you start spinning tassels like i'd have to check with the licensing department john yeah so here's the deal is on. These women make less money money when they are on birth control or when they're not our way yeah or when they're not ovulating and so women who are oscillating men you know pick up on that in in their primal brain and the actually pay them more money but women who are on birth control. They're actually men are selecting differently. Don't there there have been primate studies showing showing that the way that primates respond to a female on birth control is completely different than when she's off now on the flip side. We wait a minute here. Okay how many guys know if a woman around them as ovulating. It's not like we're babboons and we turn bredon. No no so it's really just picked up on by fair moans. Their hormonal changes that happen so leading up to ovulation. Testosterone is rising so we're going. It'd be more energetic. We're probably going to be a little more flirtatious is well on these subtle changes that we pick up on and on the flip side you know women are actually selecting selecting for mates based on their end each c- complex which is what tells us about immune health and what we select for off of birth control is a man that is genetically connecticut different from us so that we have the most viable offspring will were on birth control. We actually select for this more genetically similar like read <hes> you know when i you say that that's like dating your cousin kind of thing and what we've seen is not women going on birth control or going off it can have disruption in their mate selection but also oh their relationships and as you started this conversation with these studies at the new study that came out saying we don't pick up on these subtle social cues at the end of that study they were like i it's not that big a deal because we would have noticed by now except that we forget that we're animals and it's all these subtle social cues that we run in the background of our brain put together that help us with <hes> you know nate selection is one thing but also how we mother how we form communities. I how we show up in the world so you. This is a conversation for everyone to get involved in especially given that. Where do you think that birth control goes when we excreted out of our body. It's going into our water supply. Why why that is does so much information. I'm still stuck on this idea that men unconsciously pay exotic dancers. There's more if they're ovulating yeah. We'll we're also plumper. Then estrogen is rising so our lips are fuller abreast or fuller or hips or fuller and so so that to a man is percent perceiving like oh viable mate. This is somebody who could burst me a baby and although you might not wanna baby and people listening zinni. I always give people were like well. I don't wanna baby. It really doesn't matter what you want an animal. It's up to you whether you wanted except you whether you do it. That's different totally totally yeah. We have to talk about my country birth control today. It's really intriguing to me because i didn't know that fact and i can tell you that as a a young adult i had no clue that women were more attractive when they're ovulating and as you know mary guy <hes> married to a doctor in co author of a book on fertility i definitely know when llamas ovulating because she's just shocking attractive and i couldn't tell you why there is look and oh. Your hair looks good today but it's just like you know i'm going to do a double. Take that i might not have done the week before yeah and over the course of a decade plus you realize that but then you wonder okay am i doing that. Unconsciously are all guys unconsciously pretty much all the time <hes>. Are we yeah we definitely will we. We you guys are you guys definitely are and it's the same thing with women that like as we're nearing affiliation without testosterone rising are libido hixon and that you know what is really going on from an evolutionary perspective is how long does sperm live will can live to five days so if we actually have intercourse we capture sperm and we released an egg and sperm already there we increase the odds of conception and so all of this is again your body program to make a baby but it only happens when you are off of birth control in this natural cycle so the mate selection but also you know our brains fluctuate. Our emotions fluctuate our immune system fluctuates. There's a lot more going on to women's hormonal house that lends itself to this idea of how crazy are we to give him medication and to shut down a woman's reproductive system and act like that's not going to have any long term impacts or any impact on her body as a whole. This is really born out of who's been been doing the research who is like who's looking at this men. They don't have this system so you know a lot of this has been like it's negotiable. You don't really need a reproductive system except we've never ever done long term studies to understand what happens to the female body like what happens when you start a fourteen year old cow on birth control and she doesn't come off of it until a forty forty four forty eight. She's never oscillated her entire lifetime. We know that progesterone is necessary for brain health and for mylan sheath development and also also neuro plasticity but without relation. You don't get that progesterone so this is like a huge experiment that we've been running. It's not controlled. Nobody's documenting it and in fact most experts is i do air. Quotes are out there saying oh it's birth control. It's a woman's right. Don't question it all right. We just had a whole episode on adrenaline final in overload and protest how important having adequate progesterone is for people who have this long list of autoimmune symptoms and so okay suppressing progesterone by using the pill but here's the thing the ability to choose when you wanna have a child is really important. What's for we get into the downsides of the pill and there are so many and what you do when you when you decide to go off of it. I think a lot of the people asking right now. We're seeing kyrie now. What is the best. What is the best thing to do. If you're not going to use the pill yeah so chapter thirteen of my book is dedicated all of that because step one if you wanna cough birth control is to have a backup method of birth control what we found out from a twenty eighteen eighteen study is not even if you do wanna baby. You shouldn't have a baby within the first six months of stopping birth control because the risk of developing childhood cancers is higher. That's that's right. Your baby is at higher risk of developing cancer. We need a lot more research to understand this now. In terms of alternatives we've got barrier methods and i know people. Usually i roll when i say condoms but let me you you if you were. I rolling person. Please go into chapter eight of my book and read about h._p. H._i._v. infections while on birth control you are you. You can potentially be more susceptible so if you're not in a monogamous relationship. A barrier methods like a condom is definitely a good idea yeah and that's that's outside of just pregnancy control. That's more like us control and if you're saying oh that's chris look at things like mycoplasma and all sorts of other bacterial things that are not talked talked about even as a sexually transmitted diseases <hes> however there's a lot of stuff that can that is designed to to transfer that way that goes beyond the the stuff that we all recognize the okay to live a long time be healthy berry method but okay. There's a lot of people here. I'm monogamous. Monogamist agnes don't have babies but i don't wanna screw up my hormones or have my significant other. If you're the guy like you care about the woman in your life tell them and and so what's your like what happens in the cool things. I'd say if you're a guy because here's the deal if you're a lesbian couple. You don't have to worry too much about this so yes. That's definitely a bonus right. They're not having to m._s. Is something that like women say as they enter menopause is is like how nice it is to no longer be under the threat of pregnancy and so these are words that my patients have used so in other barrier methods we have cervical kat and we have diaphragms now those have a higher failure rate so when we look at birth control and contraceptives we have to really weigh what risks are you okay with and in my book go through hormonal birth control whether it's <unk> dis implants new ring patch the pill all of these things and then we go into these non hormonal birth control options so there's also the copper are you d it works well for some women not for all women of all contraceptive devices. This is the one that women sing the praise. The highest of it has a really high efficacy rate it needs at its very low to sell your and in addition women who do well with it. They do really well with it. No who doesn't if you have a history of heavy periods painful periods endometriosis copies not going to be for you. This is not not coated with hormones. Just a piece of copper wire basically yes. It's copper and so that's something we have to consider as well so i recommend that women get testing for inflammatory markers there zinc copper levels tested and also look at their thyroid because just because you're not having overt symptoms like we want to test out before and then again six months later to make sure we're not ending up with any issues. Dear is researched <hes> you you know the research says over and over the copper does not go systemic however the research studies will also caution. If you have a copper storage disease. Maybe shouldn't use news. We shouldn't use that so that tells me common yeah just to be super clear. I write about cars a necessary nutrient and as potentially talked nutrient my new book superhuman that comes out in october. It's dan amazon for anti-aging right so if you're a woman who has a copper problem and wanna live a long time and look good and you get copper i._u._d. It's going to bad things and if on the other hand if you're deficient in copper or you have normal copper metabolism it could work really well but without having tested you wouldn't know what's the test you'd get in order to know whether you're copper sensitive so you can do genetic testing and then in addition to that actually looking at likes rule applies on or n i like looking at zinc <hes> as well because those two minerals really oppose each other <hes> they compete for absorption russian and so that's why we don't we don't supplement zinc without copper and vice versa and we have to be mindful of that but you're absolutely right. This is something that is more common than we think and in addition to that. If a research study uses light cautionary language it tells us that there's something they were seeing that maybe they couldn't report on wasn't in the scope of the study eighty or wasn't statistically significant enough to enter into the study. There's something these researchers are seeing that says you know. Let's just pause with this one now. Another form of of non hormonal birth control is fertility awareness method these days you can leverage semtex devices like natural cycles or daisy and so this isn't a guessing guessing method in fact this is very scientific method in which we really leverage mathematics to predict fertility and you'll have a fertile window. No you can't get get pregnant any day out of the month. No you won't get pregnant from french. Kissing <hes> there are people who have <hes> been told a lot of things about artillery and i'm sure you go into this in your first spoke is not really there's only one day that a woman's fertile spent sperm can live longer and so that extends the fertile window to anywhere from five to seven days but you know i love. I love this method. Even if it's not your primary method of contraceptive on baby baby making prevention it's also a great way to get into with your cycle into literally biohacking. I oh hack your cycle and your hormones because you can start to make correlations between cervical mucus cervical position temperature and also what are your other symptoms going on on throughout your menstrual cycle in fact i'd had patients that have caught their hypothyroidism will. They're doing fertility awareness trucking and they're like why is my basil body temperature always always so low we do a test and there it is there hypothyroid so it's an incredible amount of data and i think it's really important for women to understand and men is your symptoms will show up before your labs show gross enough changes not as to fall outside the reference range of sick people for your doctor to catch onto who it which is why it's so important to be collecting your own data even on a daily basis and understanding where you're at and if you're gonna use them fertility awareness method you can couple that with condoms with other sexual activity that does not include a penis entering the vagina so there's no risk of sperm and there are the people who elect for the pull out method and i was shocked when i got into the research because his doctor you're taught never ever ever condone that it's not okay but when done correctly clearly it's gone about a four percent failure rate. That's with perfect use. It was just going to say it as someone who really looks the way things work. I'm pretty sure if if the sperm isn't where it needs to be it's probably gonna work most of the time but four percent federate. It's still you know if you have sex a couple hundred times a year. You i have a four percent failure rate well. What if you had some awareness of when you're obviously didn't practice that method then you're now approaching really really good odds in in frankly. That's that's what lana and i do it. It's like look you can tell even without all the cool fintech. That's out there right now. You can tell within about three or four months. Oh i'm about to ovulate. I'm ovulating now because there are very obvious changes what you're taught what they are in your mom may not have told you and then okay now. I know this is my risk window so this is crazy. I'm gonna change my behavior during my risk window and you're you're. I'm calling it. Risk could be if you want to get pregnant. It's your opportunity period but whatever you wanna call that your your behavior during during that time you're probably going to have a lot more during that time because guess what the guy in your life is going to be all over you because you're ovulating and because you're gonna feel really horny because you're relating because that's it's what your mitochondria are doing to you so that's it. You're like oh. This is the risk period. I'm going to use a barry method just for this one period of time or at least i'm going to do the pull out thing and shockingly shockingly. This is what people did for thousands of years before we had latex right yeah yeah and i've also had patients who were like because i'm practicing using fan. I've actually started engaging in all these other sexual activities that i had no idea i was super into so it's also an opportunity for exploration legit doesn't and always have to be intercourse. So what does it look like for you in terms of like there's there's so many other things to do. I'm not the expert on that but let me just say google louis koukoulas lots of information for you but that's something a lot of patients have reported increased sexual satisfaction because now they were like well. I don't wanna risk brisket. I'm feeling nervous about this. Let's do x y and z instead got it. There was a ruling game changers my last book about that you know find the stuff you really like in the bedroom trim. I'm forgetting the name. It's exactly at something like something about fantasy unicorns after forty six laws but it it was basically the people who are <music> are happier with their life so like you know i've always wanted to try ex and they go out and they do it so this could be a good thing that i want to be really clear. We're talking about the pill that can mess with all this stuff and we're saying here's the things you do but we're also talking about shots patches <hes> and <hes> appellate's like essentially anything that's giving you a natural levels or types of estrogens well the synthetic estrogens and the protest in so this is something really important for women to understand is not progesterone that you make following ovulation is not the same as protest in and protest thin is when we get into really big trouble in terms of like we've always vilified the synthetic estrogen because of the clot risk what we've come to understand is not synthetic progestin changes the woman's brain it's associated with higher risk of depression and we can certainly go into all of that but so when we talk about it yes the pill. She's the leading lady. She stepped on the scene. I with the most research she's the most widely ios however that i you d that's progestin. That debo shot that's progestin so these other forms of birth birth control also have progestin so when we talk about synthetic hormones. We're talking about all hormonal birth control so don't don't be like woo okay. It's all good because i only use the new uber ring. I don't use the pill and now sorry like all of these forms of hormonal birth control come with these risks and with him you know as we were talking about at the top of this with the alterations in female behavior processed in has been shown on brain scans to decrease the cortisol thickness of the brain rain which is explains a little bit about the behavior changes that we see when women are on birth control because this helps with regulating emotions and this is where we see that women have an increased <hes> reward seeking behavior and so there have been studies to show that women can on birth control can be more prone to becoming addicted to drugs to alcohol okay hall like we we don't have that. Stop break on our brains. <hes> when we're on hormonal birth control and like you were saying the top of this we're not judging anybody buddy for using birth control not anti birth control and i use the pill for ten years to become a first generation college shouldn't but given now that we understand that over sixty six percent of the population in developing alzheimer's are women and ninety eight percent of women have used hormonal birth control at some point in her life. We've gotta start asking these questions and if you are a woman in who used it. I'm right there with you being like okay. What did i do to my brain. How did i sabotage my medical. Andrea depleting co q. ten taking this birth control. Oh wow <music> out. That's an interesting thing. I did not write about that in my my fertility bucket even know about that so if you're listening to this you've probably heard somewhere another. Ah that statin drugs one of the reasons that are so harmful for us that they deplete something called coenzyme q ten which is necessary for cell membranes and for your mitochondria turn food errand energy. You actually have a study that says that the pill does the same thing yesterday the pill depletes co q. ton and in addition to that what's really important for women to understand because the conversation about wilbur control impact. My fertility always gets dismissed. People like that's a myth straight away however there arsim mechanisms at play that we really have to question and i talk about the coq ten <hes> completions in my book and how the mitochondria are concentrated in in a woman's ovaries now we will make co q. ten ourselves and we will support ovarian health equality however as we age coq ten declines in production and you're on a pharmaceutical. That's actually depleting co q. Ten also vitamin a and vitamin c and vitamin e. These things that are really important antioxidant and there's alterations in vitamin d metabolism we deplete full late and b twelve wilmer on it so these are all things that will make it so that you do not make the most viable viable egg possible we cannot at this point saying birth control causes infertility. We don't have causation enough data for causation however by by this mechanism it may impact your facility especially if you are delaying fertility and saying okay. I'm gonna come off the pill thirty eight and that's what i want to get pregnant. Well your cocoa cokie. Attend production is down if you've been taking antibiotics if you're exposed to life is like what have you been doing to your mitochondria and there's this other question that i raised which is not we we know that birth control is actually toxic to our gut bugs and anything that is toxic to the microbiome can be toxic to these little girls also called mitochondria that actually evolved from there so there's a lot of mechanisms it play that i just don't think researchers have been asking the right question and so many people shutdown and want to say we've already solved this. Shut it down like don't ask any questions. That's anti woman anti woman anti science is not asking the questions not on staying curious and not being humble. I'm sorry here i'll just say i think i've said this before. The pill is anti woman to be really straightforward. If you love the woman in your life and she's on the pill she's at greater risk for huge numbers of diseases and things is that suck the quality of life in alter her ability to perceive reality around her as in the cool factor the day so i would say it's up to you as as a friend of something like this or a mate of of someone on the bill. It's like look. I care about you. I will do my part in not having a baby so that you can have have the full experience of your health and so when someone says that if you're opposed to the pill for health reasons that you're posted women that's just industry market. There's no other there's there's no other word for that like the pill in fact we'll say birth control not even the pill but but readily accessible birth control has raised the income of women by about thirty percents developed countries. It's really a good thing to have control of reproduction but the pill is not the same as control of reproduction and when people can fight those does is because they've been influenced by industry propaganda from birth control companies and you know. I'm not a conspiracy theories there but i understand marketing. I'm pretty good at it and and you can see what's going on here so do not just if you're listening to this and you're you're stuck in that that loop that was planted by someone trying to sell you hormones uh-huh you might pay attention yeah all right. I'll get off my soapbox. Talk about no but like it's great because i talk about this in my reversing metabolic mayhem chapter are in which a drug was introduced new on and just to be clear. Everybody these are drugs. These are medical interventions. Even though they're passed out like candy i would actually argue your doctors more cautious with sugar these days than they are controlled or bad now. It's so true though so with this them there was a new progestin justin derived from andrew jans spare anum is what it's called and it came out in yeah is it's you'll still find it yazmin acela and they knew it had a potassium sparing effect act and this was bare and they marketed. They actually did tv commercials where they were like. This is all these benefits and is this wonderful thing in the f._d._a. Got all upon them and was like wait a minute like they're actually like this is not a good thing because women at higher risk of stroke and heart attack so if you're women with polycystic ovarian syndrome like you needed listening because you're already at higher risk for those things and in addition to that you like bayer was saying this will fix your p._m._s. but they actually had no studies dated back doc that up and a lot of experts sent by the time the f._d._a. Stepped in it was too late because the indoctrination was done among healthcare practitioners and hand among women thinking this pill will cure my p. c. o. s. or excuse me p._m._s. vera to recent clinical studies around <hes> the active ingredient in a called kito prime and in both of these studies that ingredients treated the emotional symptoms of p._m._s. m._s. and and the way that kito prime works is it goes in and it provides a molecule that allows krebs cycle this is the ability ability might have contrary to make energy it provides the compound that primes the pump so you can take a new molecule of energy end of the top of the krebs cycle a molecule of food. I should say and turn into energy so it's <hes> it's one of the things where wow up regulating mitochondrial function can help with that because at certain times times even if you're not on the pill if your energy production is going somewhere other than into your brain you like oh and then you have less emotional regulation but yeah i wanna we know aside from those claims about p._m._s. in the pill and things like that and certainly some pills seem to do that. You wrote on on your instagram that the pill depletes b. two b. six twelve full eight magnesium zinc selenium co q. ten vitamin c and vitamin e. Does that mean for people who are listening who are on the pill oh and are choosing to stay on the pill oftentimes they like the risk reward for me isn't there should they be taking all the supplements with a pill at least minimize harm absolutely so you're going to need at least a multivitamin or prenatal and in addition bringing in that co q. ten as well in khotan it depends on the quality of the product right because we don't like there are some products out there that is like four hundred milligrams is like the sweet spot but lagaan look breath and i always wonder about absorption but at least one hundred milligrams is like what i like to see coming in if women are on thinking about their future fertility and really wanting to protect their health and you know it's something about your products. Would i want to say is is on if you are feeding the might a contract to do their job then when you ovulate relate so you're gonna ovulate a more viable egg better-quality egg the corpus ludi m that's left behind will produce not progesterone. You'll see reduction in those actual p._m._s. a symptom so that's a great mechanism and how that works but you know there's so many doctors that have pushed back on me and say why are you telling women to take prenatal or multivitamin like why would you do that with birth control and i say okay with stanton's. We know there's co-captain issue. So what do you say oh. We're going to supplement with coq ten. Okay great so matt foreman a leading drug four diabetics depletes b twelve what you tell your patients otake twelve okay so birth. Control is depleting the vitamins like full late and b twelve which by the way if you're taking the pill. There's isn't a nine out of one hundred women will get pregnant so it's ninety one percent efficacy rate with typical use so that's nine percents failure with typical use. If you become pregnant the by the time you you know you got a positive pregnancy test. You already needed that fully and fully it's been depleted so that's the other concern that i have here but when eight list list to doctors when a list of all the nutrients which you know some of these people push back and they're like where are the studies to prove this. I'm like this is their studies since the nineteen seventies. This is is not something anybody debates anymore like when i was getting my nutrition degree this was part of standard curriculum okay so this is not something where people are like. Oh i need to studies to prove that i need to take a multivitamin prenatal while on birth control like no you need to take fine and you need to also recognize you have to have your diet dial because if something is hating on your mind or cadre like in hating on your microbiome and impairing liver detox vacation causing all of these issues in your body you don't have of as much wiggle room as the average person to be binge. Eating sugar are eating inflammatory fights without feeling worse and that's really the name of the game. It's not food shaming you. It's not you know trying to push you in one direction or the other edo just for the sake of doing it it's really about how do you live optimal life and be a high performing individual all and as we were talking about like it is something that a lot of women i've had women who are so you know i had a practice in the bay area lauded executives liz at tech companies women who are on birth control who are like. I'm losing my edge. I have brain fog like i am not sharp one in the room like and having these complaints the come off of birth control. We work them through that and they're like. I just got a promotion like i just got. Originally i am the killing it at work and so that's when i really started to get interested listed like what is this brain health connection between birth control how it impacts our brain but also how we can work with the menstrual cycle to be more productive wherever free you're on in life whether that's being stay at home mom or being an executive in a corporation either way like women world is always demanding that you multitask. <hes> you know when when a doctor says how dare you there's no there's no science behind this. Here's the deal well. There's twenty nine million papers just on pubmed and you go back to nineteen sixty when a lot of these doctors apparently got their license. There's one hundred thousand new papers a year coming on but back in nineteen sixty you had a you have microfiche germany l. You don't know what that is but before we had the internet they would photocopy things until they're microscopic on transparent little pieces of plastic and you have to shine a light and magnify your through it so you could go to library. He's not even making this stuff up yeah. No i know i i'm old like that. Okay so back then. They couldn't keep up with it kit okay. That's one hundred thousand years now. There's about oh nine hundred thousand new papers a year coming on and it's going up exponentially from nynex increase so i'm pretty sure that these doctors haven't read all twenty nine million nor should they. They probably have been searched and when you do a search with specific lens like you have. You're gonna find some interesting stuff so the answer for those people is basically because science yeah well and insisted like it's his crazy thing than <hes> you no doctors. They have the education they received in medical school. It's a lot of information then they have the education they receive in residency and then they have continuing medical education and so what does that all mean. They're not actively doing the research like you. Don't find a lot of doctors who are like lenny like. I can't solve a problem with my patient. Let me go into pubmed and spend hours is there. There's other databases otherwise but it there's a filter going on in terms of the education that they're receiving and that's an issue and so your doctor is not a bad person awesome. They've been taught that this is the pill for every female. Ill you gotta lady part problem. Patterson birth control problem solved and if you truly believe you were taught that is the the best solution. Why wouldn't you offer it and it's just a you know. It's very narrow tool toolkit. I've a much broader toolkit and it's something that it's also you know as you talk about. Oh unicorns people are like how do i find a document. It's kinda hard to find a doctor who studied nutritional biochemistry concurrently with clinical nutrition then became dr love love sitting on pubmed leg you know and there's not a lot of doctors and especially when he got caseloads of like thirty to forty patients that they're seeing a day they're tired. They're exhausted austin. There's a lot more going on to this story. Which is why in my book i sat out with the medicine and women's hands so that they can make an informed decision about their body know how to talk to their doctor no at labs to ask for and know that like their symptoms are not their body betraying them in fact. It's an opportunity to heal on a deeper level. What is acne today. May very well be hair loss in a few years and then they ended up being an issue with your cardiovascular system diabetes in ten years so this is the thing we have to recognize our hormones or not expendable and our hormonal symptoms are often rooted in a whole lot more dysfunction lying under the surface. I want to talk about a post birth control <hes> syndrome but i also have a overarching questions when you're done with post birth control syndrome. Do you have better. There's sex when you go off the pill. Oh women report this all the time to me. <hes> we get my customer. Service are women and be because there's a lot of like we did have a customer service gentlemen and he was like. I don't really want to hear about women's vaginas dot lake. I don't know i don't feel appropriate on women report increased lubrication tation better orgasms on filling their libido upticks that is if you do the work on hormone birth control actually alters your liver's genetic expression of sex hormone binding globulin and the research yeah and the research has shown that it doesn't return to pre birth control states now i will same with the protocols in my book which were developed one on one with patients you can get fat sex hormone binding globulin back and track because epigenetics is everything and and just just for people who don't know that this is something that will stick to your sex hormones so your body can't use them. You don't want a lot of that otherwise even if you have a little bit of that testosterone that that makes you horny floating around and i mean that for women as well as from just different levels it won't do anything because he gets sucked up by that stuff totally yeah and that's that's not a bad thing you guys guys because it's a protective mechanism. If you're on birth control your body's protecting you from too many hormones however it's a big problem when you come off and with testosterone. It's not just about libido. It is our wakeup. Kick ass repeat <hes> when your testosterone gets too low you find yourself low energy all day crying all the time and your muscles rules can actually start to atrophy so you don't have muscle strength now. Take that to your pelvic floor where everybody's like doing their kills and whatnot that's also involved in orgasm so oh this is really important to understand while we're on birth control. Were not bathing in our yummy hormones. There had study showing the younger. You've been put on it. The higher odds you will have pain with sex. Despite rooney's that's called an in addition. You can have vaginal atrophy. I've talked with physical therapist who have seen twentysomethings whose vaginas looked like fifty sixty something year old women because of this vaginal atrophy in tissue changes when you come off and you restore that hormone health women do report better sex because we'll you're on on it if you do actually get in the mood and then you get lubricant and then you finally do achieve orgasm sometimes those orgasms can be really painful and as you know i'm in your game changers book talking about the benefits of orgasm so you guys unique game changers annual beyond the pale. If you wanna get your orgasm health dialed in and modulate your immune system. It's don live forever like all that. I'm going to be like a crass guy. I'm putting on my manhattan for a little while here <hes> not that i'm not normally wearing it but this is this is a bit of a leading question but asking for all married men out there. If my spouse goes off the pill am i likely to have more sex or less sex than i do now. You're likely to have more socks in terms of my clinical experience and what so. I mean but think about it for women and i go through this. I have a whole chapter in my book and for women. It's complicated so one thing you have to know. Men is not everything. Do you do during the day adds up for either like safety and security or the bad dude and so this matters juicing is actually four play or hiring someone to do the dishes if you can't do the dishes but it's those things that like for women you have to understand fanling handing a penis enter your body it puts you in a really vulnerable position and so as an animal and the evolutionary spectrum you know we have developed to be like i want a man who takes care of me and that i've got this safety and security and also if she's not banana stressed out with her cortisol pumpkin she can put that energy into reproductive health like the fastest way to get your libido back is to find a way to signal to your body throughout the day that the environment is safe so you know while and birth control. It's this. It's this thing where we think like oh. She's gonna start birth control. We're gonna have more sex because we don't have to worry about babies and it's the sneaky anyway really prevents pregnancy is that she is not in the mood anymore. She has vaginal dryness pain with intercourse. Inability to achieve orgasm are paying with orgasm like who who wants to have sex when all of that is going on and if it's painful those neuronal pathways almost get like i want to say solidified but like we know there's plasticity here so it's it's not forever but if it's painful organisms avoid pain it's what they do and so she's gonna wanna move away from not pain sensation and so it's a very interesting thing thing that i've seen time and again with my patients. They come off a birth control and they're like whoa. I thought women like my doctor told me women don't have the beat goes in like a libidos a nice bonus bona and like yet. I'm really into my nate yob. Because now you can smell them. You can perceive them. Your brain is changing your fluctuating like your hormones are made to give you superpowers superpower's. It's like they're. It's the best kept secret of women's health is not they actually help our brain in so many ways they help our performance. When you work work with your menstrual cycle if you're an athlete and you're on birth control league their studies to show that your <hes> your muscle gains are lower your performances impacted so so and when i say that people might be like why are we talking about sex and athletes sexism athletic event okay like it's an athletic event and if you do it right you can get a little cardio in for the day bonus that is fantastic. I just i i love that all right so there's our answer what happens ends in the first thirty days. When a woman goes off the pill maybe for the first time in decades <hes> so that's when we can see see the post birth control syndrome symptoms arise so what is post birth control syndrome like all syndromes. It's a collection of signs and symptoms that liked to hang out together now. When you understand understand that hormonal birth control impacts every single system in your body then you can understand how these issues can arise showing up with like new onset neurological symptoms so maybe maybe you start with migraines brain fog on your starting to have anxiety or depression coming off of birth control. Perhaps your digestion changes. You were having some digestive issues on birth control and now you come off. Those things are getting worse. This phenomenon i've observed when women don't start ovulating right away when they come off a birth control which is not uncommon uncommon by the way can take up to three months. If you had a normal every like clockwork twenty day but say cycle the four birth control it can take up to three months to star automating again but if you're not ovulating you don't have progesterone to oppose estrogen estrogen cause issues not only for your liver gallbladder and so we can start to z. gallbladder issues. There's women who lose their gallbladder. After coming off of birth control and part of this is the mechanisms that's been put into play it. Also it impacts your thyroid rate your adrenal glands. We actually see that. There's massive h._p. Dysregulation with women on birth control so they lean one way or the other where they're like anxious all the time or they're feeling depressed like they've got that burn out h._p. Is a hypothesis pituitary adrenal so in other words your brain and stress system gets jacked totally totally and you know part of that is because hormonal birth control is inflammatory so they've done studies where they measure women's blood her c reactive protein which is a marker of inflammation shen. They put on birth control in some women. It's three times as high with the fastest way to develop a chronic disease jack up your inflammation and so this is really important understand because when women come off of birth control in those first thirty days it usually starts really subtle and then what we see happens is not around four to six months symptoms really start to appeak but for some women actually a lot of women do this head down push through you. Gotta be everything to everybody. Ignore your symptoms managed them the best you can until you can't handle it anymore and that's when you end up at your doctor and that might be a year later two years later so your doctors not making the connection that coming off a birth control oh you you never reclaimed your natural menstrual. Cycle your adrenals. Your thyroid number got the support. They needed your gut. Microbiome is still struggling. You know in fact we see women who have repeat yeast infections vaginal yeast infection on birth control very well known side effects but lesser known is all the dental research where are used as overgrowing in their mouth and that doesn't just go away once you stop. It's also overgrowing in your gut so if you're somebody who's like i can't clear candida out of my god. That's what yeast is issued a start looking in your mouth. You gotta start looking in other places because hormonal birth control is skewed that microbiome enough and created intestinal hyper permeability ability leaky gut. That's not going to heal itself just because you stop and you know what's really shocking. There was a study that came out of harvard showing if you have a family history of crohn's disease or inflammatory bowel disease which also includes ulcerative colitis you're at three hundred percent increase risk of developing crohn's disease after five years on the pill and you know oh how lacking start that can start with little ulcers in your mouth you're ignoring and being on hormonal birth control can trigger auto immunity coming off of it can be a triggering event for autumn unity nitty any hormonal fluctuation that is somewhat extreme getting pregnant having a miscarriage <hes> giving birth menopause <hes> you know starting your period for the first time can trigger autumn unity so that's why we see this whole collection and people were like it's so much stuff. It can't possibly be related to birth control to that. I say if your natural the hormones can impact every single cell in your body and every single system then. Why are these synthetic ones any different when you're taking such a high dose that it shuts down brain ovarian very in communication because that's how it works shuts down your entire reproductive track. Why would that not have an impact on the rest of your body. It's clearly to me. I'm like that is some with the most craziest logic. I've seen women's medicine right up there next to hysteria. Your uterus is just wandering. That's crazy so there's so much evidence but so sixty percent of women are on the pill instead of the other methods well sixty percent of women are using birth control four symptom management. That's a a big reason and so scary right because you might be using birth control for acne and trading it off for a stroke or heart attack and not knowing this this your right to know that and to make informed decision women with polycystic ovarian syndrome. These are women who have irregular periods. It's rooted in a metabolic disorder. There are issues use with insulin regulation and inflammation there at higher risk of metabolic disease and yet they're birth control. Their doctor says we fixed your period by the way that bleed. It is a withdrawal from a medication bleed a not a real period. There was no ovulation but with that these women are already at highest risk for diabetes for heart attack or stroke stroke and we know with a new study that came out that taking hormonal birth control for six months or more in your lifetime is associated with a thirty five percent increase risk of diabetes when you enter menopause that to me is like we've got a pause because that is something a woman has the right to know so she can make that informed decision <hes> it's such important information that i'm super happy to be able just to share it on the show and something that i've known about and believed believed end for almost almost twenty years and it's your trendsetter man you aware it was actually <hes> t s wiley <hes> wrote a book called sex lies and menopause sometime in the late nineties. I read that book and i'm like wow it's one third scientific references isn't she's actually been on the show not that long ago <hes> and so. I remember that weird conversation where you sit down. I sat down with the house with at the time and i'm like you know i want to go off the pill and it's not because i want to have babies just because i care about you and it was we had a conversation about not here's all the here's all the science and all the data and it's it's going to be good for you. I mean for sure and if you just want her to be happy not walk around and cranky something that is really interesting is that when the depression study started coming out the big ones that we saw at a denmark in two thousand sixteen showing this is high correlation between birth control and new onset of mood symptoms. There were so many researchers and doctors lined up to dismiss what you know. Essentially women have been saying saying since the introduction of the pelham but then another study came out and i was so grateful were they started looking at the mechanism of action and we understand the pill is inflammatory while oh inflammation in the brain is always a bad thing but in addition to that hormonal birth control actually alters your trip fan pathway so you make more quinolinic acid you make wore neuro-toxins instead of nourishing compounds in the brain and the progestin so again that synthetic progesterone may actually be up regulating free caracal so oxidative stress in the brains. We've got inflammation neuro-toxins oxidative stress so when she's really cranky and irritable it may not be you get navy navy what she's actually popping not pill pack every day. Wow okay a new study just came out. I talked about it and one of the recent episodes about willpower some scientists using advanced algorithms for computational analysis figured out the mechanism nissim of action of inflammation on reducing willpower and they're just oh we can we can show this so when there is inflammation in the brain. It's it's predictable and the mechanistic behaviors that cause reduction willpower so let's see the pill causes inflammation inflammation mason reduces willpower. The pill liberates women. I kind of like willful women can't can i say i would like all human beings is men or women to have their full willpower because guess what will power does it allows you to overcome your biological urges to act like an asshole that says the guy guy used to have massive inflammation. Here's when you have enough energy. Even if you get an urge to yell at someone you will act like an adult and not with them and if you don't have enough energy or you have too much inflammation you'll get the urge and you won't have what it takes microseconds to make that decision and say something and then later you'll be like i'm really sorry i said that and this applies applies to men and women equally. That's what will powers for its your ability to overcome the biological urges because if you just listen your biology let's face it. All we will do is basically eat and have sex all the time and that would probably be the end of the species. It's probably a good thing that we have this dynamic but i i would like all of us to have that because we're we're meant to be nice to each other and you got to have enough energy to do that. Anything that sucks energy from women is bad news for for all of us yeah or alters mood. I mean this is something we are seeing. That depression is rising. We are seeing that suicide. Risk is rising you know in fact when these studies came out about the mood correlation and birth control <hes> we found so we thought like oh estrogens the bad guy so women who took a combination pill most commonly prescribed of estrogen in protest asked him they were twenty three percent more likely to be prescribed anti-depressants now if they were a teenager so if they were actually a teenager they were eighty percent the more likely to develop depression and at higher risk of suicide so teens actually had double the risk of suicide after one in year on the pill now peaks within the first two months but the first several months and then but it continues even a year later and we thought okay well. Oh you know this is like a combination pill issue. If women are just taking progestin only which is most commonly prescribed to new moms they were thirty four percent percent more likely to be prescribed an antidepressant and teens who are taking the progestin only they did twofold increase risk of their depression and this is when this research came out. I just stand back and say well. What's up with postpartum depression 'cause i my first book was on postpartum health and i had a lot of theories around that a lot of things that we've seen in the research but now to understand you actually can bring in this progestin only birth control pill or a progestin only i you d and that increases it by over thirty percent in women that are likely to be prescribed an antidepressant means new onset depression has happened which led to the research. I mean you know it's really awesome. We're seeing more female p._h._d. Researchers stepping up to study brain health and there's actually some in canada but we're gonna see like women are really taking hold and control of this. This issue and a lot of us are speaking up. I mean when i was talking about eight years ago. I was not popular. I will say that now talk about it and i get way more women and i even have women women in their sixties. Who've read my book who right knee and say for the first time in my life. I finally understand what happened to me that i wasn't crazy. It wasn't in my head and it was never ever broken like my doctor told me like it wasn't that way. I finally feel validated in my experience well. That's that's a gift well. I still think though you ought to file a patent imagine birth control pill plus antidepressant plus co q. ten and maybe some zinc in some vitamin e. I mean imagine the riches go ahead. I'm kidding yeah and let me just say for people with the alteration that trip to fan pathway. I often give people who write in the and say well then the answers to take more trips fan right no okay. It's like an i love lucy down the conveyor belt with chocolate again. I'm old life that <hes> no the answer is not to start up the machine and try to move it faster now. A five each teepee won't have the same effects that can't go clinic acid pathway that we know of but really the answer is like really the answer is get off birth control but if you can't go there you have to be feeding the pathway with things like magnesium which is depleted by birth control b. six depleted by birth control. If you just look like and this is the thing is like no matter what theory of depression you subscribe to whether it's the serotonin theory of the science theory. There's there's evidence in both camps that birth control can in fact lead to depression that so much of what goes on is in indirect. It's not that you took birth control. The cause depression you took birth cause inflammation ikaz increase in free radicals. It caused nutrient depletion all of that led to your depression and so that leads people. Would it be like well then. It's not birth control causing it must be fine right but i think that your and that's why i'm excited to be here. Your audience is freaking smart like they're way ahead of curve with even a lot of clinicians that i engage with a he you know bio. Hackers actually understand a lot of these more complex lab tests than a lot of doctors do because it's just not what they've been trained in. There's <hes> there's definitely there's definitely influx of people just saying having to pay attention and i. I think it's happening across food is happening across nutrition. It's even happening across aging and that leads us up to the final question on the show today so gentlemen your functional doctor. You know thing or two about hormones. You've got pretty much all the tools of anti-aging your disposal disposal if you want them. How long are you going to live. Oh man i saw your thing about living to one hundred eighty and i'm like can i can. I reach for that goal if i'm living if if i am lying healthy in my body let's go hundred hundred and twenty because i have this thing where i'm like. Look if i can't jump on a bike and ride and like do all the things that i love lake is not really living like. Are you really living so i gotta say if you ask a hundred and ten year olds hey are you really living like. Do you want to die right now. In less than an awful lot of pain they generally say i think i'd like another year or even if they're not riding a bike but there's nothing that says you couldn't be riding a bike at one hundred well. I mean we see these centenarians around the world that are totally kicking ass <hes> the women i do my hydrotherapy and i do all those things because i wanna live long but also i want to live long and prosper. I want to be very healthy. Star trek jokes read but at the end of an episode on post birth dude. I'm such a nerd. I was definitely not the cool kid you got your nerd erred points on that one for sure will join your website is dr brighton dot com d. r. brighton dot com and your new book is on the pill or i want to get the title exactly right beyond the pill but the subtitle is long and complex so beyond the pale is your new book and then there's some other words that come after that that you don't need to put into your favorite search engine to find it all right so dr gillian brighton beyond the hill and i just have to say this. There are women in your life. <hes> probably no matter <hes> who you are or what you do who would really benefit from this kind of knowledge. Ah it's it is totally normal and healthy to have control in reproductive freedom. That's not we're talking about here. We're talking about reproductive freedom done in such a way that doesn't suck your willpower and damage your biology and caused biological harm. That is the opposite of your goal. <hes> and i believe that this is something we can do and it's not even not hard to do and the side effect. Is you have better sex loses right so that's why this episode matters. If you like this episode <hes> share it with a friend someone who would benefit from this. There are lots of people who have this knowledge now. This isn't a fringe thing it might have been ten or twenty years ago. This is just hey this is what all the scientists showing and you say all the time so get on the bandwagon and say i'm gonna take care of my algae and all levels including on the reproductive side you will you will win so show the episode. You'd like this review it and have a wonderful day. You probably noticed that i mentioned a lot of new biohacking anti-aging technologies on the show and they'll get to see and share almost every new thing that comes out and some of the companies that talk about really upgraded my life and i walk the talk by partnering with her investing in some of the companies that i really love bulletproof radio was created in his hosted by dave asprey the executive producer is selena pica cheer and the podcast assistant assistant is bev hamson research is provided by darcy himes and all technical aspects are handled by our podcast mastermind brock armstrong. His podcast is information purposes own. The statements and views expressed on this podcast medical advice. This podcast including dave asprey in the producers claimed responsibility for any possible adverse affects news information contained herein opinions of gas s._r. Their own in this podcast is not in daughter. Accept responsibility for statements made by guests as podcast is not make any representations or warranties about guest qualifications credibility individuals on this podcast may have direct or indirect financial interest products or services referred to herein if you think you have a medical problem consult a licensed physician podcast is owned by bulletproof media.
Nick Lachey, JLO, Harvey Weinstein, and Whitney Thore
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The no she talks Hollywood tales from Your Business to see real data. y'All says you'll be a dead texted back to the number one like rely. PODCAST panda out. Hello and and welcome to juicy scoop. I hope everyone had a blast at their super bowl parties This is the second year in a row that I have not been invited to any there used to be a time where I find it to a couple of so hard to decide which we go to Not Anymore but you know what it's okay because because my sons and I we went to our club and we played golf and we were home before halftime. which is all I care about but let me just say something about hosting a super bowl party? I have a friend who hosted such a great one for like a long time. I've been going. Maybe the last like eight nine years and she had a water slide kinda like Vicky galveston's waterside in her backyard and she would heat up the pool and the boys would would be able to swim because they're going to get bored during a game and she had liked the guy making like the gourmet Turkey burgers in the whole thing and alcohol and all the dips and you bet the money and it was really fun and then last year shoot two years ago. She was in a remodel and then last year she had like smoke from the fires. Come into her house and this year she posted and she's like I did it a lot of years and I just don't know that I'll ever do it again. Ed and so I wrote her and I said you know what I just want you to know that we really appreciate it being invited all those years and all the money money and the effort that it took and I also understand once you stop doing something. That's like a huge undertaking. Like that. Like you have a big Thanksgiving or a holiday party. aww Once you stop doing it you're like Oh my God what the hell was ever think you'll never do it again. There's no way and people don't realize but oh you have money in your. You know the person's coming you're not cooking everything it doesn't matter. It's still so stressful. I have my own post traumatic stress often talk about when I throw parties and that is that people are not going to come and it's haunted me since the second grade told the story before. I'm very good friends with this girl. Today she's one of my dear friends so I'm not gonNA say her name but in second second grade. She went around and passed out invitations to her pool party. And it happened to be the same day I was having a party. I passed out my invitations and many of the same girls got invitation to both and I invited this girl to my party and she did on invite me and this is when people could pass out invitations in front of people you know and this is why when they say oh kids our pussies today. I disagree I. I didn't need this fucking memory in my life. Okay it's haunted me by entire life so then my best friend Liz goes I am coming to yours. Don't worry she literally was the only one everyone else said. We're going to this girl's Party so I came on that day and I told my mother and she's kind of like oh I don't even think she cared and then the other mother called her and said and I heard my won't go. Oh I guess we have a problem. Okay we'll move ours so then. My mom moved ours which was just are typical. Very Jackie goals. Schlager what's over. Her name is from real housewives of New York New Jersey. We would have. It was in the summer birthdays. June fourteenth breath come over for swimming. Then we get a carnival ice cream cake and then you spend the night and my mom makes a killer breakfast. That was party for eight years in a row never deviated from that. We never put a deposit down anywhere we never had so and bring a blow up slide. We never had any any special foods. Catered that was it okay. This girl was having a similar party but they knew how to do it better so we changed our date to the following week so now it was a week after school got out and the next day the girl came up during those. Oh I'm sorry I forgot to give you this but I really did want you to come heather so then she invited me 'cause so horrifying the mother that I wasn't invited and my eyes welled up. I was so touched that she was being so sweet that we that I went your party. I was thrilled to go the week later was my party will. Now everyone's been out of school for like I don't know eight or nine days. Nobody remembered except for Liz and Liz's came over and the two of their and more and more time pass each car drove by and I don't live on a busy street and finally my mom had to get out the directory and start calling people to remind. The party was happening and Several of them couldn't come. But if you did if you showed up. Oh my God I'm sorry. And they came so anyway you now. That's why I have an issue and when I had heather fest this year I had a few people text v day of and say we're not gonNA I'm not going to be a kid. It's too hot where you live and my Tara goes you just have post traumatic stress from that party. When you're seven and I go? I do and she was what you shouldn't because everyone had a good time to go. I know but I can't handle it and then I said to myself how they're why do you have to throw a party ever again in your life. I basically throw a party sometimes for a weekend when I do stand up. People are thrilled to go. I don't have to make any food. I don't have to worry about them not coming because they always sell out. And that's party. If you WANNA come to my party then you come to my live shows like this weekend Washington. DC City winery. This Friday and Saturday that's February seventh and eighth The eighth eighth almost sold out so is the seventh. But they're still tickets left. Go right now to Heather McDonald Dot net get those tickets. San Antonio Texas February fourteenth and fifteenth breath be there. That's two shows a nights. A four shows total four parties that we can people palm beach. Improv March. Six eight and San Francisco which was just announced bounce and selling really fast. That's cobs March Twentieth twenty-first and O N we're going to be selling my merch that you've been begging for at the Washington. DC shows okay and that is the adorable. I'm `a delight hot pink water bottle. I get stopped everywhere. The Pot socket the straws does and the very cute that keeps your wine cool which says let's rip it. So that's all available at the DC shows this week so I will see guys. They're we're speaking of parties. You know whose mother throws a better party than my mom. Pat McDonald Kylie Jenner. Oh my God so oh story had her second birthday. A lot of people were really freaked out by this big baby head. Blow up thing. You'd walk in through the party because she instagram. The whole thing Kylie but I guess it really is part of the Dad. What's the DAD's name again? Travis Scott is the dad who who he did a similar thing with his own head for like a music video but this party was the most extravagant thing that her head was dolls goals there was a whole merch store of just stormies party and it was really insane but my thought was listen to one hundred and sixty million instagram followers. Stormy has her own Palette and make a pallet and so this was clearly going to be a write off I would think they would be able to write it off or people would be giving it to free cell who cares really But it was a little. It was a little insane but Cardi B. was there and her daughter culture and you know what have fun go on an amusement ride at this thing who cares but stormy is cute but this also my question how many eye shadow palettes to someone need I. I think of using the same eye shadow pallet going on like three and a half to four years I understand if you want one pallet of like some funky colors. I don't know if these people are collecting them. Almost like you would collect like hot. Rod cars is or cabbage patch kids. I don't get how many people have shadow palettes and is eye shadow inexpensive inexpensive thing to make or I. I don't know because I just think about how. How Long I? I don't know that I've ever even gone through an entire fire. Eye Shadow pod and Ben like Oh. I'm out of that shadow anyway. Stormy has got her own shade okay super bowl or an talk about the Super Bowl Party. It'd be the actual watching so it was Jaylo and the only people that we care about the halftime optus show Jalen Shakira. And at first. I'll be honest. I was like okay. I get Jaylo. But why does she have to share the limelight with Shakira. I I didn't really get it I love Shakira. I think she's great. I feel like out of the limelight for a while. She doesn't have like a new hit. And if I'm I'm wrong right me angrily I don't care. I think she's super talented. I just didn't really get it but then I liked it that it was two women to Latinas doing it. But when I was watching Shakira Shakira full disclosure. I was like all right. Where's my Jaylo like? Let's get to jail so she cared as a couple of songs and it's a great great job okay. I'm just saying I was more into Jaylo Jaylo. I've seen I just. I love her. Look her hair everything so she starts Danny dancing around. And she's wearing that black outfit and I did not realize she had her silver outfits under it so as she's leaning over in like pretty much at G. string bottom. I saw this shiny stuff and I'm like that it looked like a maxi pad. It looked like like like she had a big big Maxi Pad. And then have you ever worn a maxi pad with G. string it's very uncomfortable and difficult and but sometimes you just have to do it and it's like it starts getting sticky on your thighs and whatever that's what I that's what it looked like until she stripped down and then she was in the tiny outfit and at some point in watching it with drake my seventeen year old and I said you know she's fifty years old. He's like wow and I go I mean. She's a little older than I am. But does she really look that much better than I do. And he's like yes she does. I'm like well your offs pretty hot and pretty useful looking so whatever so we see her dancing. A lot of people had a problem with the crotch featuring the crotch a lot. I didn't have a problem with it. I don't like that dance move. That seems kind of like a male thug. Like dance where they grab their crotch like almost like doc almost like I'm walking with a limp. Like she she had like the pimp cane a little bit like all right but all in all I liked the girl power. I love that her daughter got up there and saying and the daughters talented as she should be. Okay her parents Mark Anthony and Jaylo you you know. My son Brandon has agreed to do the reenactment of on my instagram. And you guys better be. Follow me on instagram. Grab like working my ass off. Kelly do so many videos a week. The content churning out is amazing. And it's honestly moving at a snail's rate. Okay I I mean I'm not even at two hundred thousand people and it's like an entire. TV show is my instagram. Okay so I don't know what I know. There's people who are listening right now that have not follow me on instagram. And there's a way for me to find out who you are and I'm going to find out who you are and you will no longer be able to listen to the show just kidding. There isn't the technology yet but anyway just follow me. It's Ad Heather McDonald anyway. I posted the greatest TV show ever Showbiz moms and dads. It's from one of the first years that Bravo even existed and there's a kid and his and his What do you call his mom? WHO's Showbiz Mom And what would they call them. They wouldn't call them Showbiz moms and they'd call him. She's a stage mom. Yeah his stage mom and So it's hilarious and Brandon. I are going to reenactment. And he reenacted. He's agreed to do it. You know have no Jaylo. And he's not a girl but we're going to make this work okay. I'm going to exploit these kids to last thing. I do anyway thought to did well. Some people thought it was too sexy. It's a kid. Show a come on. Who cares she they did great? It was good girl power. Speaking of girl power. I don't know offices such good Getting I think there should be a girl code. Let's not let's talk about girl Code Retard Girl Power Tova Girl Coat. We've talked talked about this a little bit on the show. Okay on social. Media Brand Glanville has tweeted and hinted that she and Denise Richards words have apparently had a little romantic liaison at some point. Denise has not responded at all and this is what we believe this next season is going to touch upon well last or was it Friday night brand new tweeted so right before Brandy tweeted. Denise Richards tweeted hey I need help any he. Good tagline ideas for me something that effect and no. I didn't quit and right after that went up brandy tweeted. I've got one one if anybody anybody. That's looking good real housewives tag lines. I've got one for you quote. I might be married to a man but I'm still allowed to eat pussy. Well everyone went crazy. They screen-grabbed it. It got a couple of hundred responses before someone who cares about brandy got to her and made her remove it. I mean she really is amazing. Go wrote a book called drinking tweeting. I mean she's really living up to what her brand is So I it's just. It was pretty crazy and a lot of people were like. Wow so we'll see what happens but brandy knows how to bring it and you know she's feeling shut out and pissed about it and I think that whatever happened to niece's feeling like betrayed by brandy whether it was they got together or she confided in her or whatever But that's what you get. That's what you get when you go on these shows. It's not just free trips and past APPs and flat. Tomi T. ADS on instagram. You you also are selling your soul to the devil so that we can watch it Pretty Pretty Juicy right there. I'll tell you okay I am I read a lot this weekend on the Harvey Weinstein Trial. I'm GonNa tell you what I recall. I may mess facts. The this is the juicy shit. Eighty to ninety women came forward. Okay of those eighty and ninety women throughout like the last up to like seventeen years ago or so Where these women said that? He assaulted them variations of assault by the way They the prosecutors in New York. I think only Following up with two people and in La La. It's only two or three people. Those were the only cases that the prosecutors felt were solid enough which is really kind of insane but you know they have to win the case so in these stories that these that the two women are saying I mean you just oh my God and and maybe the a lot of them didn't WanNa come forward either or go through with it all because they may have come they may have shared their story and then when they really thought about doing a trial being cross examined they may have just said you know what I just want to be done with it and you really can't blame them so in the two stories I recently read about One girl was there and It was to meet with him in a meeting and he like immediately as her sitting down went up her skirt and like I guess like fingered her than she. She was so shocked. And he's like I should know or she got up and he's like oh I'm sorry. Sorry sorry then. He made another meeting with her in which she went. So the main witness to talk about is It just command and it sounds I mean. Her story is horrible and brought many gasps in the courtroom but what I think I think is going to be challenging for. The prosecution is the relationship that continued after and they involved emails. That were quite complimentary on her part to him like. Oh I'm bummed. I missed you and I remember with that one. And then also always great to see your smile. And they've had psychiatrists psychologists. I guess attest to the fact that this is normal that when someone has a traumatic rape happened with someone that they we have no not a stranger in the street but some they know that sometimes they do continue a relationship after the initial rate to normalize it somehow somehow in their head and also out of fear of the person that originally raped them so like really careful what I say because it's obviously a very sensitive subject and I have never been in this position. I'm just looking at it as someone who's read some articles and just really wondering how a jury will in fact Decide on these cases because he has a top notch defense team and part of the defense is going to be a strategy of like. Hey jury look at this unattractive disgusting old man and look at these beautiful women. Nobody Buddy if he wasn't rich and powerful and could give you Oscar type roles would ever be with him sexually the only person that would be that'd be with him sexually are people that can gain something from being with him sexually and therefore this was a consensual relationship mutually beneficial to both of them. So who's really the Predator now. He's almost being tricked by these beautiful women who are acting like they like when they really just want to partner movie so that's sort of the strategy and then of course. These poor girls were believed when he said. Hey I think let me. Let's have a meeting. Let me talk talk to you. I think I think I've got three projects that are coming. I actually. There's a couple of parts that would be great for you for both of you. Let's meet at this hotel lobby. Oh my God i. I'm so so tired or oh we're going to take the meeting. People are looking at me. That was another thing. Someone said that. Sh- this girl met him in the lobby for meeting and then he's like I'm being recognized. This is so uncomfortable. Let's go up to my sweet. We'll continue the conversation there so I don't have to be bothered by people realising I'm the most was famous Oscar maker in the world and the girl was like okay. I'll do that. And then of course he forced himself on her and I totally. I believe that he's done all these things but it does make it difficult for someone who's not but in that situation to be like why is as aspiring actress after she had the most horrific experience of her life writing him after a couple months responding or possibly even meeting him again. Ed Is it. Because she's like I'm trying to normalize it or is it because she's like well God have already been through the worst. I might as well try to see if his original original promise of getting me apart will now happen because of already suffered this awful experience I do appreciate Ah the strength of these people coming forward. These women coming forward because so many just were like forget it because of this because they make them look like they're not being completely truthful or their intentions weren't solely out of fear that they might their intentions may have been a little self serving so it's very interesting listing One thing that she talked about the just command was his genitalia. And that almost look like he had ahead of China and he didn't seem to have any balls and that she also witnessed a needle in the trash can of A kind of Viagra that he would insert inside of him which many people have testimony to back this up that he he had an erectile dysfunction problem so he would shoot himself up with like a Viagra but through a syringe and and that obviously was when she realized that that was terrible because that could have been exchanging of bodily fluids to like the blood. Or whatever from it at you. If you didn't if he had some disease were aids she could have gotten it. I mean that's something I don't even know if they brought up the how fearful that must have been. Anyway this is just crazy but definitely believe I believe everything that they said. I think what's just GONNA be. The challenge is the Relationship after an even Jessica said some of it was consensual she agreed to have a threesome. And it's just it's just very it's hard for someone that has not been through it to understand. It is what I and I have not where you know your perpetrator then and becomes your romantic person. Or somehow you're almost like agreeing to out of fear that they're now going to be more angry with you if you don't comply or or hurt you another way. She said that he was threatening her father. And a Lotta people said he was very threatening very bully like very like gangster territiories oftentimes went God. Could he send some thugs over to my house. It's just unbelievable. You're hearing all this and you think about his wife eighth his second wife so he was married and I believe he had a couple of kids with his first wife while he was married to his first wife. He started seeing Georgina Chap Chapman and and She they were married from two thousand seven to two thousand seventeen. She is an actress and also a fashion designer who is gorgeous I remember always seeing them at the Oscars going. How is this woman with them? Oh well it must be because she is able to have her own line of gowns that all these actresses where which then we found out according to other people allegedly that he would get his Oscar Oscar nominee actresses from his movies to wear her designs when she was first coming up and one of those people that that I guess agreed to where it was felicity the city Huffman and I remember pulling up the photo of Felicity Huffman in the scout and it wasn't great it didn't fit her frame. It was an empire waist which means it comes right under the BOOBS. It wasn't flattering and here. She's finally at a place where she's like going to the Oscars probably was deemed dream. Cream trusts I've thought about the dress I'm GonNa wear to my first Oscars for the last fifteen years. If all of a sudden someone said no you can't wear an off the shoulder fitted navy with the big split up the leg. Heather like you planning since you were thirty one. No you're going to have to wear this ugly white flowing empire dress that Harvey Weinstein's wife is GonNa make you otherwise. We're not going to advertise your movie at all. All right. Bring that empire dress over. So she immediately filed for divorce. When the eighty or ninety women came out But I mean what. What was that relationship about and was that one of just who knows was with that weirdness as was it a sexless marriage did she have to put up with this weird needle thing and Or right when she got married to him to choose like stop having sex with them and then probably got inseminated by somebody else. I have no clue what what it is with your our kids. She's trying to live a private life yet. I've seen her in a few events in some. You know getty image type shots and and I think she still designing her close marquette and her kids are obviously innocent. And all of this. I understand wanting to protect that And maybe immediately getting divorced helped protect some of the assets that she would maybe leave if she stuck by his side. I didn't you know had to participate and paying for all these attorneys. I don't know it's just gross. This is so gross all right. Let's talk about Pamela Anderson and John Peters so Pamela Anderson as you know she's the Baywatch Babe Playboy on the cover of playboy more than anyone else she was married to Tommy Lee and they had the two boys that are gorgeous. And now they're in their early twenties brandon and Brandon and Dylan and I think she did she got the the leads from nine to two one. Oh she named both her kids after the not too L. leads printed Adila Anyway She just got married. She's fifty two. She got married to John. Peters who is a huge movie producer really was was in the limelight. More like maybe twenty years ago He seventy four. He's not a bad looking guy. There Malibu neighbors. Apparently they dated when she was in her early twenties and he was in his early forties and they met the playboy mansion one nine but they didn't get married. He claimed to have always always been pining for her. They reconnected in Malibu. They got married two weeks ago in which Brandon and Dylan were there for that wedding as good sons do when and their mother is married for the fifth time yes. This was each fifth marriage. Anyway they set out a statement. They're asking for our respect sore them. I'm not giving it to you because I'm talking about it but During this very difficult time because after really working on it for two weeks they have decided that there are two week long marriage has concluded and they love and respect each other. They're going to remain best friends and they're going going to continue on their way and occasionally run into each other at the Malibu Mart. I don't know but to give you a little history on Pamela Anderson. So she mary Tommy Lee and if you can recall when I had bobby brown not the makeup person the other Bobby Brown who was I had a crazy life and a couple of good books. But she's She dated Tommy Lee for a long time according to her she. She didn't even know they were like officially broken up. He met Pamela at a party or something said come down to. I think they were in Mexico or Hawaii and they got married there within days of knowing each other and she wore a white bikini 'cause she's bride and it was just a classic story everybody like. Oh my God Tommy. Lean and Pamela Anderson. They got married and they had the two little boys but it was very tumultuous. There's Times please recall call. There was no accounts of whatever verbal abuse. I don't know that was just crazy stuff going on between the two of them and that they seem to raise these two boys well and then she married kid rock that lasted for like two weeks then she married Rick Solomon. Who is this guy who dated Paris Hilton I believe filmed the original sex tape of her? He also was buried to Shannon Doherty from nine to one zero which is a big weird connection and they got divorced then then she remarried him again. Like years later payroll Anderson remarried. The Rick Salomon years later and then that lasted very short time and then she shed some long term partner for a while for few years and now she married John Peters anyway I feel like these boys have been through more than Anna from ninety day. Fiance and the beekeeper. I really do. I mean we thought that was awful all that she's now telling them that they have to stand up for another marriage didn't work out and the beekeepers coming back from Turkey and the boys are trying to just enjoy their ice cream. Well Oh you know what boys look at Dillard and Brandon Lee. Okay so get ready you you just go to as many Malibu weddings that if your mom asks you to go to Kay because that's what you're going to have to do if you're GonNa make family work Very just just interesting interesting. I also mazing that you get four five men to say will you marry me. Will you spend the rest of your life with me. She is gorgeous us and she does have one of those voices where she talks like a little soft voice and she's funny and she's giving and she's a Vegan. Dan and I can see how she can get anyone to fall in love with her. I really can name if I just talked like this. You guys things would be better for me. I don't know so nick. Nick Luce and his wife Vanessa. They've been married over a decade. There are running some new show. They were on They have three kids. I've actually met invested Panetta. Vanessa Ana a couple shows that I've done and she seems very pleasant. And as you know Nicholas Shea and Jessica Simpson were married very long time ago and they had a hit reality show. And that's really how we discovered. How Funny Jessica was anyway? As you know Jessica Simpson is on a book tour. So Nicholas Shea and Vanessa luce come on to promote their show to Hoda and Jenna Bush and Jennifer Bush. I love the way she talks. Because she says it's such an interesting phenomenon. It's kind of the way she talks. Anyway she got the part she gets. She's the Co host now fulltime. Anyway they are talking to nick and Manasseh and I have to say I thought this was not great. And I've been in that position where you go on a talk show and you think you're promoting something immediately want to discuss the Kardashians Chelsea handler. Or something. Like that. And you're kind of like really cool about it but after a while you're like can we just get to be so right right away. Hoda says so my God. It's great to see the two of you as you know you were married to just Simpson at we just had Jessica Simpson on. It was really sweet because she said great things about you guys that you're both really happy for each other and you send a beautiful gift after something that she had gone through and that that friendship is is still there so I just WanNa ask you. Nick you know she's come out now that she had suffered addiction issues. Choose we're you aware of that back when you were married to her. And he's like no. I really wasn but as you said it was a long time ago like just we don't WanNa talk about it. This is my ex wife. I'm with my current wife. We've been married eight times longer than I was ever married to Jessica anyway the Nessa. The wife goes hold hold on. I'm sorry we can just backtrack a second What was the skift? And when did she say where she received it. Oh then he goes. Oh I I don't know it was I think being maybe after a child is born or something bad interview or something you center very nice gift and she said it was very well received and well. It's interesting because I I don't even have her address so I don't know how we would have sent her gift. But whoever out there sent Jessica Simpson Gift From my husband and I by which I have no knowledge of thank you for doing. Yeah and nick is just like deer in headlights. Um and then Jenna Bush probably just try to go on some other subject. I do think it would have been very uncomfortable. Call right when they got back of the SUV living leaving the studios in New York When she's like really nick really all right? When was this? What do you send her? Was it something I've ever received for me like you're just going to be sending your ex-wife gifts and not tell me about it and then she can go talk about on a book tour like one one is going to be enough. When is it my turn? I've given you three babies on this other show with you. God Vanessa doesn't mean anything like I don't even know now. I think my assistant suggested it. What assistant the one I had eight years ago? I don't know what she's talking about like God. Well did we tell the publicist. We didn't WanNA talk. Talk About Jessica. We did but I guess they thought they. I hope I thought she was being nine. Oh what a nightmare anyway. Everyone's going crazy about it and I'm here for it and I love it. So why guys. My Patriot episode. Last Friday was so controversial. Peter Nye did a fantastic patriot. Juicy see crimes and his first-hand analysis of the weather and Kobe's crash and it was it was really kind of crazy and spot on in retrospect act and that was really interesting and then we also got into Aaron Hernandez so if you are not part of patriotic or you want to check it out or see the other episodes on some of the other tiers you just go to heather into all dot net or you go to patron dot com slash juicy scoop check it out. It's new content and once you join you get to listen to every back episode in your tear all the way back. Of course. It's all commercial free and now for really fun and interesting interview I had had with the star of. TLC's my big fat fabulous life Whitney thore. Hi Whitney I'm so excited to talk to you. I've got Whitney any sore from a big fat fabulous life which comes back for its fourth season your every Tuesday right on Tlc. Yeah it's actually the seven season the seventh. How did I get the more and you know when I read the fourth? I think I went to like your Kapiti or something and maybe it was what I read the four hours like. I feel like this show is going on. Today is actually the five year anniversary so season one actually aired today five years ago. Yeah and in season seven aired last week that's awesome. You have lots of exciting things going on in your life we see from the trailer you fallen in love you got a beautiful diamond. Cute Fiancee Sapphire. Actually but yes. It's beautiful really. It's a yellow Sapphire. Yes Oh the fire. Oh I've never seen anything like that's really pretty. I noticed that a lot of New Brides getting not just plain all diamonds. Which I love? You've got to really cool. Yeah I don't think anyone that I know could have afforded a yellow diamond at large and I actually A little story that most people don't know I was actually engaged before when I was in college and I had a yellow sapphire with diamonds around it Chase doesn't actually know that that's what I really like and but that one was much smaller and came from Ebay so this is definitely an upgrade. That was actually really one of the questions of how many times you've been engaged. Nineteen Times hasn't been my time just the second nut nineteen like digital stab No not quite there yet. I could never find enough men who could stand me long enough to have more than two engagements I think so. Let's talk a little bit about for people that are not familiar with your show and how it came about. which is really interesting for what I knew you? You were in theater. You're a theater major right in college so it wasn't like yours stranger to being in the spotlight and being a performer. And I love that. You're working on a radio show as well to show your personality and and then get into the viral video and how that came about. Yeah so in two thousand twelve to two thousand twelve. I was working on a morning radio. Show like you said I was on air personality and producer and end my show mates. Were looking for fun. Youtube Ideas So it was my task to create the Youtube Channel. And you know put stuff on the people who might want to watch so it was actually my show mates suggestion that I should do. Dance videos and call them factor all dancing and my first reaction and was that I didn't want to do that and I didn't want to call it that and then he said but you know people on the Internet left that people and when he meant by that was like people on the Internet left to hate that people But he said you're really good dancer. It'll be good music you know and So I took because advice and I did a couple of videos at the end of two thousand twelve and then I think it was the third Video that I did in the very beginning of January wary. I recruited my dance partner. Todd who I've dancing with for twenty years And we learned a little choreography at the why it was really bad. It was filmed on a laptop. We didn't know doing showered in three days. We had to film it. Seventeen Times to get it right It was really really not we felt our best work and then it went viral so that was very surprising and people ask me like what do you do due to go viral at am I ask because I did everything wrong. in terms of what you would think would make a video go viral. I I always remember working on this. TV Show we used to joke about how our bosses that were not really in touch with what's going on would go. Let's make a viral video. Oh well you know what look at. Let's only get one hundred views now. Of course there is no like if if someone knew the trick to it may be Special L.. Because you just never know. How did you realize that it was getting these amazing amounts of using response? Well we had it on facebook facebook Originally and it had so many shares I mean hundreds and hundreds of thousands of shares which. We've never seen anything like that. You know we used to get fifty fifty shares and think that that was good And then I started getting contacted. I mean the next day you know by the Huffington post was the first person to do an article and they. We asked if I could put it on youtube so that they could. I guess embed the video or something so then I put it on Youtube and now I think it's got a lot I don't want to say I think it might have like nine million year. Eight million views or something like that on YouTube But it already gone viral on facebook and so I started also getting an email l. like from Steve Harvey That next day I was like what is going on and I remember sitting with my dad at Putera looking at the video on youtube every time we refreshed it would jump up so many years and is that like dad like I think this is going viral. And he didn't even understand what the word viral met. You know he was like once so a really weird moment I can actually feel my life changing and night moving in some direction and my friend said to me. You're going to be on Good Morning America and I would like laugh so hard I was like okay and then like two days later. Good Morning America called so And was that Tyler Henry. Now that is the psychic that I I liked to make fun of. That's funny no No it wasn't but it was actually my. It was my show. Show me who. I suggested that he was like you're going to be good morning. America and I was like okay. Sure I was so short on all these fun. Pr Trips and and I assume the conversation was this is great. You know just doing what you're good at loving it not caring about being a certain size that a dancer has to be and so then when did Like the reality show conversation start to come around where your agents agents pitching it like. What tell me all about that? Yeah so I'm actually so this'll happen. January I did. Most of the press appeared appeared on all the shows in February and then in March I got an email actually in my spam folder. So more stories you should check your spam folder eh from DC executive. And she had seen me I think on the today show and she said. Are you interested in collaboration And at that point I had actually already quit my radio job because it was a toxic environment and nobody there was really happy about what was and what was going on. Really that's weird. Yeah even though they encourage the whole thing then what turned turned jealous on you. Yeah now yeah. It was really bad like the. We never talked about it. I went and did Steve Harvey and then I came back the next day and it was scheduled for like to talk about about nine forty which is a really crappy slot. Obviously and then we didn't even talk about it and I remember my dad texting me being like two weeks. Get Out of there. Like they're we're doing dumb things like taking my picture off the walls and stuff like and it's funny because if they if if that environment Hatton been that way I would have still been working there and we all would've had a TV show but you know and that. That's the lesson to like. I understand jealousy is a natural feeling and I've admitted to my listeners. In this business I get jealous and I struggled like I'm like don't that's not being a Christian. We happy for your friend you know it. I'm like Oh i. It's hard for this deadline article. You know a now I feel like I'm much better with it and I'm I wonder if those does co hosts and your bosses and stuff ever look back in there like that was really fucking lame way to be because we really cut off our nose. Better face yeah yeah. I'm not sure I think. Also though part of it was that the the male influence there. I mean my job on the radio show was mostly just I made self deprecating jokes folks and told stories about being fat and all that kind of stuff so I think dispense despite the fact that I you know that job like wanted to use me for what they could to see me actually become successful for something that they truly do not respect me for that. They truly Rulli. He gets disgusting that they truly You know hate me being fat to see me be successful in part because of that was it's just I think really difficult for them and they couldn't they couldn't take it and whatever so whatever Boyne is I knew that that wasn't going to. I didn't know what coming. That's what I want to spend my life doing so I e mail and I just responded like okay okay shore so in a couple of months they flew me Out to La to meet with a production company. So I'm lucky because most reality shows a production company finds you and you fell the show and then they pitch it and I'd have lots of production companies emailing most of these were ideas about like dating shows and just the stuff I didn't want to be involved in so this was a little bit unique. In the fact that a network found me and then Found the production company so I felt more competent about up at because the network was already interested so they flew to L. A.. And I met with production company. Called Pilgrim. WHO has Produced my show for all seven seasons and I like them. They like me I keep hall. We shot a seven minutes sizzle reel which is very short shorts. You know look into whatever my all my life was at the time and there are a lot of possibilities I mean they could have said. We're not interested. Percents are shoot it again or shoot at this way or we'll take a one episode. We'll do a pilot but it came back in today to order the whole season so it's just been really everything was green lights. It was really wild. And then that following January I My season one premiered so amazing mazing and so my me no is that. Wait with Henchi. Everyone onto ask how she was doing. So she's it's your in your boy. He's doing well okay. Well he's stunning. I have a cat so so one one of the things that that you also have. Is this disease the initials R S. And it's an ovarian issue sir. Can you explain it a little bit. Yeah it's called Poly Cystic Ovarian Syndrome. Ironically politik means many cysts. But you don't even actually have to have have the cysts to be diagnosed with it. I do have says I've got about thirty sunny jewelry But it is an into crying and hormonal disorder. It's so much of it. It's not well understood. So even with the diagnosis process. They look if you have three or more symptoms of it and there's nothing else that can explain it. Then you'll be diagnosed with P. C. O. S. so There's not a lot of awareness Brought to it I I have all the symptoms which include infertility will actually. I've never tried to get pregnant. But of course I only had about ten periods in my whole life Tilleke There's insulin resistance. which not all women house women who are overweight with PCs? It is because because of insulin resistance. Which I've had since two thousand five that of course in term can lead to diabetes and heart disease and stroke so yes along with infertility insulin resistance? There's also acne hair loss. There's a big imbalanced hormones so people with P. C. O. S.. I have too much testosterone. Too much too many Andrew Jans which can cause hair growth on the face the body and hair loss on the head. It's a really typical thing especially for women because a lot of the things that we associate with an entity fertility hair. figure the all those kinds of things. PCS can manipulate and change about your body. So there's no cure for it. You can try to manage the symptoms and oh you know everybody is different but yeah it really talks cure. Say They can't remove the SYS- no well on the sister and actually the issue like I said you can actually have syndrome without having assists for me. My sister aren't painful or anything they're just there. You can see them on an ultrasound and you know it's no big deal really. There is nothing you can do outside of taking medication to lower your insulin guy exercise you know kind of self care things. There's there's nothing else to be done about it because you had a very rapid weight gain when you were not aware of your illness. which is one of the reasons is as you saw the doctor so from what I've seen it seems like you've kind of just maintained this this size for a while? Is that what the goal is that what you're doing is that good and healthy just to accept and be this or or do you have doctor saying that you have to try to lose weight even even though you have this disease. That's kind of hindering. It right What should I say decides? I gained about one hundred fifty pounds and continue to to gain until I was about two hundred eighty pounds Then I was like five years and then moved to Korea and when I came home. That's what I'm saying since the show. I feel like as the viewer from what I well since the show. Yeah well I've lost fifty pounds. Actually congrats so which actually. I don't don't think that's something that to be congratulated for it. All but just found that out in the premiere episode for me in terms of hell. It's a holistic realistic picture. So I'm not concerned about what the number on the scale says. I'm concerned about things like my blood. Sugar I'm concerned about how much I can exercise. I'm concerned about if I sleep. Well I'm concerned about if I take my medicine so all of those things are important to me if those things those healthy behaviors result in a way lost spine if they don't that's fine I have an eating disorder history. I even lost one hundred pounds right when I came back from Korea in in two thousand eleven and I lost a hundred pounds and I was extremely unhealthy. I lost it in eight months I had an eating disorder. Anyone from the outside would have been like. Wow she lost one hundred pounds really quick like she's really healthy In fact I was incredibly unhealthy. What what was what were you doing to lose that sharp starving starving mostly? I exercised about fifteen hours a week. A very little and then when I did eat I would just throw up everything that I ate that was wrong and even before that in in my life I would go on diets where I would have a certain you know calorie intake in so I would think okay like okay. I can drink Dr Pepper and just not eat dinner. And if I really wanted that doctor Dr Pepper like that's not healthy. I lost weight because because my calorie intake was so low. But that's not healthy so I think the idea. That weight is so tied to help is Bullshit mm-hmm and it's just not something that I'm really interested in track it occasionally and like I said I lost fifty pounds and didn't realize it but it's not something that is a prominent factor to be and if I feel healthier not right well I think that's great. Let's let's get to your seat. Let's get into your juicy life so you have these great parents that are featured on the show. Glennon Glennon BABS. Some of the questions for my listeners does does your mom Bab still wear a pantyhose to the pool. You you know I don't know actually but I'm GONNA go ahead and say that ninety nine percent I think if we went to school she would wear pantyhose again. We have not been back to the pool but yeah that's the type of thing that would still do for sure. That's something like my mom with due to my mom's in Hamburg but like very much about like was just not like jumping in the pool. Having a blast like just to be like so so now you had this buddy buddy who's been one of the regular people on the show. He started to show you guys were platonic friends right right and then it came romance and just tell a little bit about people want to know as much as you can share without spoiling the season. Where are you guys? What happened is the fiancee at all uncomfortable or jealous right? Well actually before we started shooting my big fat fabulous life but he and I had like slept together one time back in two thousand thirteen. So that's that's the the history well with with let just like a drunken night. What was was it? Yeah we were a little drunk. But I was like re either huge crush on him. I was really into him and then we got really close as friends friends and it just. We've always been friendly but we've always been kind of flirting. It's funny like we really don't feel like we flirt with each other but then we see as like on TV and we're like Oh let like it really does but we really don't believe that we do until we see it so yeah I think everyone you know like really likes me buddy eight together and we have a great chemistry and he just came over here last weekend like spent the night and hung out in the guest room and Hamilton joke. We were doing like an instagram. Live and I made a joke like yeah chase. Does you hear that. I was like wait. Actually he does it but I'm GonNa tell them he doesn't care. I mean he did in the beginning and I think I'm not sure what's coming up on on the episode tonight but I've seen the previews like you can see chase kind of like I'd say confronting but it's that sounds a little dramatic I think but kind of confronting buddy because he believes that I have kind of a co dependent relationship which I can see from his perspective but when Buddy got clean and sober I took a lot of responsibility for him and really want to always kind of protect him and and even though I know that's not completely my job. I am just very protective over buddy and chase like it was hard for him in the beginning. especially 'cause chase lives in Wilmington. I Live live in Charlotte. So we're not even together so there are plenty of opportunities where buddy together Jason's not here and that would kind of weird for him and and we did have a fight. Actually we didn't have our first fight over eight. Now that I'm remembering and I think I think that is I have no idea when that will be but I did see a part in a preview so yeah but they're good now and you know I'm engaged. They're good and where. Where does heather standing all this? That was buddies Ex girlfriend right or girlfriend. Yeah yeah well. She's been my best friend since I was eighteen. Which I have a light problem with the fact that buddies ex-girlfriends instead of like Whitney's best friend annoys me but anyway yeah we've been friends for twenty years? That got really weird. I think she's trying to act like she didn't really care if something happened between us but then when she felt like last season I'm trying to think in real life when this was and I can't in my time frames. I cannot understand when this actually was but it aired last buddy I kiss and she got really weird about that and I we see fan saying saying well Whitney and buddy where together furs and it's like we were like you know. We slept together. I but we didn't have a relationship buddy and heather had. Hey Long I think it was three year like relationships so Yeah she got about that and so that was the end of that and nothing ever happened with me. Buddy not ever again are so heather still going to be featured in show this season still. Yes okay yeah absolutely yeah she just put the put the Kabosh on. Yeah we didn't do that again. And so how did you meet your fiance. So I actually met him. So in the premier You saw kind of the first time or one of the first times alone together. I'm actually met him on New Year's Eve of last year and we weren't shooting at that time time so there were no cameras around. But I go out for New Year's Eve Party with my business partner Ryan who is chase's friend and chase was there and I thought he was like it's funny because I thought he was really cool. Really cute and I had said to Ryan Before I got to the apartment I said like is he single and I don't think he'd want to date him and I was like but I thought it was really cool really cute and we went to this New Year's Eve party and Ryan dates kept introducing chased ace to all of her single friends. All of her like skinny single friends and I was kind of like bitch. What are you doing like I'm I'm here and I'm I'm with this party and I'm interested? I like what are you doing. I was so annoyed and then we like he was in Charlotte so we worked out together like I think the next day or something. I think we had lunch together. One of their time as a group And then the next time I was really with him alone. What what you can see in Last week's career episode. So Yeah and how did he feel about putting on a mike pack and being him he was so nervous us. I mean he thought he was like I mean in the beginning. Of course we weren't like dating or anything so he was like well. I don't really think I mean really be on here. I mean I don't I just like so. So nervous and like the whole world is like very weird for him and I. I don't know I think we're kind of weird place even now. Now because he's not used to any of that like kind of attention and stuff and it's kind of stressful. I think four him for a relationship and I've been a little bit I would say more reserved than I normally would be even on social media and I've seen comments from fans like thinking that's weird but I'm like you get it on TV. Like I. I mean you get like all of you get all of that like I don't have to like you know I don't know go overboard overboard. Like sharing instant. Yeah it chased them. I didn't instagram live the other day. He's just funny he just gets nervous and he's so cheesy cheesy on social media. That's actually what kills me. Because he knows what people are looking so he's so cheesy on social media. How does he cheesy just like how God like? I think last week before the episode posted. Somebody like I tease him about as posted like. What's your favorite love story lady? And the tramp beauty and the beast. Maybe it's me and Whitney way thor skew but more howdy bet it on social media prior to this and how has his numbers grown and our girls trying to slip the ends so he was on instagram. Reminding you got like twenty twenty two thousand twenty three thousand followers like first time. I tagged something. So so he he was your last weekend and we were hanging out he ryan went to go to this bar with one of their college friends. I went home so I go home and I'm on instagram. And all of a sudden I see he chased Severino started out alive video so of course I go in there to see what they're doing and they're they another dislike tipsy at the Barbican silly and all these these people in the comments really go. Hi Wendy I m like hey and then all these women are leaving like emojis like Kissy face emojis. Being like you're you're so hot while Blah Blah Blah and. I'm like excuse me like you only and it happened when I had a boyfriend before back in season season two like women will message especially bigger women because they have this idea like Oh. I've seen this man with a big woman so he must just love big women and like exclusively like all I have to do is be big and they will message. They are ruthless and like lert and like Ktar Disgusting like my one of my ex-boyfriends used to get like nude photos and stuff on social years. I'm like y'all get the fuck walkout year. Women women are awful. And I've and I've always said you know the first person I use this example of it was like the Khloe. And and Lamar now. Lamar obviously was drugs. But but I was always like girls that are going after. Lamar are a hundred percent. More obsessed with Khloe Kardashian then they are with Lamar so these girls that found him are obviously they found him through their fans. They liked the show and they're obsessed and there's like a fine line between like fandom and then like wanting to be you and then also like seeing like I. I wonder if I could be the one that he cheats with and destroy. Whitney's life and it's it's well it's the same thing I'm like you guys are my fiance. Yeah that's why you even know about him. Doing this is just my boyfriend. He's like what are you actually. I got slightly annoyed. I really Dan exactly. I mean you should just not. You just have to know like that's just par for the course it's going to happen. I mean that's why it's hard to find signed when the girls are single whether you are in better pump rules or whatever to find that guy that is just the right balance between. He's okay with being on camera but he doesn't want to outshine you he okay with someone approaching them and asking for a photo. He's delightful but he's not going to go home home with that girl right. It's hard and I think it's and it's such a quick adjustment you know. It's not years and years of being an actor and you get a little part now. I've got a series now. I'm in a movie. There's no like growth to it. It's overnight especially when you're a companion to the star it's even more overnight than let you encountered so good luck. Yeah I mean I trust him. I trusted but I'm saying I think it's frustrating but it for you. You know if I trusted him any less like it would be really difficult because like I said we're not even living being in the same city. And why are you not living in the same city. Well so his plan was to move to Charlotte. And then this event I guess November. No bembibre he'd had this plan before to maybe open up this bar that it wasn't going to happen and then love above a block so all of a sudden in November out of nowhere they end up getting some step straightened out and it was like. I don't know liquor. Licensed off all this whatever. And he's like. Hey so we're open the bar and I was like. Oh okay. So that was in November. So now he's opened up a bar and woman so he has delayed his moving plans Until he figures out like what's going on there he says he just can't really leave right now so yeah it's yeah for sure he would. Yeah our that was. Our original plan was for him to have already be moved down here. So and how did you decide decide to choose Charlotte and moved to starlet. Well he went to college here and he has a lot of a lot of friends and you know things here. There's nothing for me in Wilmington. I just moved to Charlotte. My Life is here in Charlotte Wyatt. I'm saying why did you move to Charlotte 'cause I saw like a like clips. Then you're I'm in Charlotte now and kind of like. Oh Charlotte's cute. But like I didn't choose it. Paul Ryan's best friend is my business partner who I do my online workout offices so we met actually a tangled web we weave. We met on tinder and over a year ago last October. And we met and started up this idea for Not as active which is an online twenty four minute daily Workout Program so oh we filmed these videos every single day. We've already done a whole year's worth of them and I was back and forth Charlotte all the time so I ended up getting an apartment here And then I just realized that I wanted to be here permanently and it was just easier for me. I'm better for me so yeah wait your business partner. Ryan is chased his best friend and you met Ryan on Tinder. Yes as a potential love interest. Well we went out to dinner but we ended up talking about fitness and then we just went home it worked out so he did. He know who you were as far as that. You read the show when he posts you tinder now when we first started talking no oh and then like a couple of days later. I guess you'd call me on Instagram. He was like your Amos. Oh He's calling me right now let me let me decline him. He was like Eh. You're famous and I was like so no. He didn't know at first. But yeah by the time we met he did and are you gonNa have like bridesmaids bridesmaids and all that while see yes but like cheeses a lot more traditional Then I am in a sense like I want my bridesmaids or my bridal party to be like Todd Towel Buddy Heather actually like my best friends and I think chasing that's weird to have is teaming. Yeah and I'm like but they're my most important people like I don't have Albany other girl for like I'm not gonNA take like some acquaintances from high school just to have like another girl like in the you know all too. Well I I could do it. You WANNA founded. I'm on the hunt for new girlfriends. So yeah we I mean all those little like details and things I think we also have different ideas about Like I thought it would be to have a joint bachelor bachelorette thing. He did not think that would be fun. So Oh yeah I he'll WanNa go to like Vegas or like Miami or something crazy which to me. I'm like let's go up to the mountains and get a cabin like we can order stripper. It's like Louie a little bit of different ideas. I think all the details well. I think that'll be really fun. And they hope we see it and you do the whole I love yes to the dress. I watched that like. It's always on like Saturdays when I'm on the road doing standups I'll just have it on all day. Yeah and I'm like crying saying I love. I love yesterday so okay. So you've got this whole fitness thing going. Do you ever think about like where you want to be in the next five years years as far as like your career we could do want the show to continue what you want to like. Take a break from it. Well now that we're on season seven. I do feel like it's so stupid. We have to get season ten. or I'll feel like I'm a failure or something but I always said I guess I would do the show for as long as they'll we'll have me and I still feel that way Now if it was you know obviously things last forever. Though in like twenty years I wouldn't feel that way but yeah I would love to just keep doing the show. I do have online dance program. I haven't workout program. I am also studying to be a personal trainer to get gin. So that's exciting. Even if that doesn't happen which I think it will. What's great about today? Is that you have a large social media following so you're still gonNA get plenty of Free Shit. Don't you worry. Funny actually. Don't get a lot of staff. Well then you need to work more. I don't know how because I don't either but I'm just saying I would think someone one with that amount of followers and stuff but you know who knows I was so now. What about the kids situation because you talked about that recently on your instagram yesterday and you have an infertility issue? So is that if you do you want to have kids and if you were to do that would you be able to have a biological biological child through a surrogate or what right. Yeah well obviously In terms of actually having kids The decision that chase the night would would have to make an. I don't know where exactly we are there but I definitely have always felt that I don't want the opportunity to be taken away for me. I am thirty five. So you know lights in the forefront of my mind that if I want kids I should get started pretty food. I've never actually tried to get pregnant so I'm not sure if I hood chances are it would be very difficult because of my P. C. O. S. Even if I were to what's the word. August extract my surrogate or or whatever which actually went to specialists and that's what he Had recommended for me. But there's no guarantee I mean there's no guarantee like you don't know how hard it is going to be I feel like when I really get started trying if it comes to a point where it's just so difficult. Maybe I could accept that like it's not meant to be but I I mean I don't know I just have and you don't know if you're open to adoption or not oh I certainly Liam but I I've looked into that as well and internationally. There's almost no countries that would give me their babies because of my weight. So that's an issue really. Yeah I wanted to. I really wanted to adopt a Korean child. I always had that my mind cause I lived in Korea for almost five years and I looked in Pacific specifically Wrigley to a lot of like Asian adoption. And Yeah might be is. There's no health. Requirement is just the BMI requirement BMI stands for body Mass Index. For that in a Oh yeah so you have so you could be skinny and have high blood pressure high cholesterol and diabetes and they will give view a baby but if you have a high BMI they won't give you a baby so it's not. I mean let's be clear like I said it's not a health requirement it is literally just a BMI requirement that it knows Downer. Nothing's yeah I mean that's just you know fact discrimination in practice obviously. So that's that's upsetting. That upset me a lot lot because and also most countries have you know other stipulations. Like you've gotTa have got to be married for five years You'd have been diagnosed with a mental illness including depression in which I have eighteen so there were so many roadblocks and thank God like I'm trying to raise a baby that doesn't have a mother like not as easy for me as I thought that it it could be. Of course I have so many amazing fans I got so many messages from people all over the world being like I will. I will be your surrogate. I will have a baby for you. I will you know it was really amazing. You know yeah they love to give you a baby actually. Yeah now I think about that I think in some way. Yeah if we really want to baby. Someone's GonNa give us some one way or the other. Well I do. Think like if someone tell with friends with fertility issues and stuff and one of the most you know apeaceful things that someone said to. My friend then ended up having to kids but was like look. If you really want to be a mom you will be and just know that. And and if you're not sure and you go well we'll see if it works if it doesn't I'm cool with that that's great. That's great if you're not so like since it's I was five. This is what I imagine you know. And that's really heartbreaking if someone does it become apparent and that's what the vision so I think. That's great. Well Whitney I loved talking to you I think your show is great. Everybody it's TLC. Every Tuesday night you're a couple episodes in you. Have lots left. Follow Whitney. What's your instagram? Because you do a great instagram. So they could follow you. It's Whitney way for yes. Follow her and look what she's he's doing to get people moving and healthy and check out all her stuff and thank you so much and I hope I one day in person this great talking to you absolutely. Thanks so much good talking to you bye bye all right you guys. Thank you for joining me. Make sure that you check out the rebel dot net for Patriot in my live shows and I will see you soon.
Women, Hormones and DNA Genetic Estrogen Hacking with Mansoor Mohammed, Ph.D. : 658
"And this is where Dave the concept and I noticed you when we first spoke the concept of thinking of DNA. Truly Dave as a language that was the key for me thus far we were thinking of DNA as vocabulary words the more genes you studied ten. Two Thousand Fifteen thousand twenty thousand twenty two thousand. We thought we could just simply stop these genes. Twenty two thousand of them figure out what they do study study done in a silo manual manner off. We go bulletproof radio stations high performance. You're listening to bulletproof radio with Dave asprey. There's certain fast your body can't make an US on. You have to get them from your diet. These are called. essential fatty acids a great place to get him macadamia nuts. Super Fat has created a delicious line of on the go nut butter snacks based on macadamia nuts almonds healthy plant fats. In Super Fat nut butters support sustained levels of energy cognition and mental mental clarity. I really like the Macadamia Flavor. Their amazing and Macadamia nuts are just delicious. There's only five similar gradients. No added sugar. They're really creamy. You get a shot of macadamia nuts almonds. Coconut butter and pink. Come away assaults. Supervisor Nut butters have plan fats protein in high amounts of fiber to keep you feeling full for longer you're going to super fat dot com code Dave to save fifteen percent. You can feel good about eating these nut butters no fillers no palm oil. No Junk superfood dot com use code. Dave Save fifteen percent. Today's cool factor the day is that well. I read the cool factor the day watch on the Youtube Channel. Because does this noise V.. Am I eating two zero. I don't think so I'm about to inject some peptides. Why because well I've been doing it for a while? It's in superhuman my new book. And it's that time of day I'm injecting a peptide called Molyneaux site stimulating hormone because it's the middle of the night in the middle of the morning and this is a peptide that makes a really big difference in tanning. Because I need to have a golden no that's not why because molyneaux stimulating hormone causes you to make more Melanin and I'm not interested Melman and my skin although I don't mind that would it also does. That's particularly cool. Is it makes more Melanin in your eyes in your brain with these junk Melanin turns out junk. Melanin is pretty darn useful in the brain because it acts as a capacitor according to research from Mexico. But that's not even cool factor the day. The real cool of the day is about DNA. I'm just doing this. Because because there's a circadian timing by the way no one at the American Academy of Antennae Medicine that I saw talked about the circadian nature of Mash. So if you're doing this stuff you may get darker no matter the color of your skin. It definitely can make darker it also though has the side effect. It can make you nauseous. If you're not used to it it also can make you extremely. What's the technical word for? It horny because as Malka called PD. He went for one attached. So this is very exciting episode for me in multiple ways. Although technically that affect doesn't come for several hours you guys are safe. But I'm I'm doing this because it's good for your brain and it opposes Melatonin so if you do this in the morning and you have a hard time resetting your circadian rhythm this. I've never talked about four. Read a blog post asana on the Dave. ASPREY DOT COM webpage. But I haven't ever said this in public but I found the studies. You want to reset your sleep. Do Your Melatonin take your your sleep mode at night but in the morning if you want to say it's not without risk but it's also not without reward and talk to your doctor about it. If you can find a doctor uses peptides. Don't worry you you will. I'm talking a lot about them. What you'll find is that You can reset your Your your sleep cycle more easily by doing this. So I've got a little. It'll insulin a syringe. Here and I drop about seventy five what are these seventy five units of Of MSA rehydrated. Stick it in my but he can put it in your arm to if you want and if you guys want to see my bite you'll have to instagram. Because I conducted test over my holiday recently months or did you see that well thankfully. I'm not seeing the but audited but the injection. Did you see the instagram part. No I didn't sorry I did a host that was mostly humorous about sending the parts where the the sun don't shine. No I did actually hit the New York Post. It was completely ridiculous but I did the INSTAGRAM test. And apparently if you take your if you if you're on instagram you get more more attention than if you don't and so. I tried the whole puppy. Hold a pig take off your pants taking off your pants what's more followers ab tested. But I'm still the fact of the day. This is terrible luther. A real cool factor the day. Now that I've got my MSA up and running. It turns out that that I did a roundup of some things we learned in two thousand nine hundred about DNA. We had this weird thing over the past twenty thirty years Craig. Venter I've sequence my human. DNA It's GonNa Change The world and then twenty years later it actually has changed the world that we can sequence but what is it was he giving us you know. What do we know how to do so? There was a backlash where DNA. It's less interesting. Let's look at our microbiome which is really interesting in and of itself and raising our and DNA sequencing to to do that as well but it turns out because of these discoveries now we actually can do functional genomics and this whole swath of new knowledge has come out and you look at what that means. Here's him stuff. We picked up this year just from our bill used DNA. Now that we're using it at scale there's a DNA from five five thousand seven hundred year old gum. which is a tree resin? The shows what an ancient woman may have looked like this is chewed birch pitch by the way. Guess we're XYLITOL. Talk comes from Birch Trees Sap so this was the original anti cavity chewing gum but they actually looked at the mouth microbes and they found hazelnut. UH-HUH DOT COM. DNA from meals consumed so almost six thousand years ago. We were having assaulted. Dock with a hazelnut production. Very clearly we I also use DNA forget why screening for DNA designer. Babies probably doesn't work because we can simulate and say it's possible to predict your kids height from looking at the embryos DNA. When people actually do this it's probable? That maybe EPA genetics is trumping genetics. Here but basically kids aren't as tall as they want them to. It'd be too bad there. You'RE GONNA have to take your kids with growth hormone actually. Don't do that unless they're really really short. You could screw them up for life. That was just a bad joke but the real truth is that if you have kids who are not tall enough. Because of a defect they are able to use synthetically derived human growth hormone to give them a normal height which is also so just an incredible miracle. And if your four foot tall person walking around wishing that this had been available for years ago you know what I'm talking about I get people saying if you're a hacker. How can I make myself tall? I'm forty I'm like high heels. That's the only way you can make yourself tall. There's no hack for that or a robot. Legs one of the two okay. We also know now now that what the first Dennissova and might have looked like and there's a controversial technique that reconstructs a teenagers teenagers physical appearance from genetics. We now know how ancient migrations shaped South Asian languages and farming We know that these weird Wales they find in greenland are a High Brits. We know the European with all lineage lasted for eighty thousand years based on ancient cave fossils. By the way I think I'm around four percents in the NFL and guys after announce this. I have inherited that less back here. Gene which is one of the things that makes me exceptionally happy. And we also found a marine parasite named after a popular podcast radio host. It turns out and they lack. DNA The Anna but still somehow can make energy and they're missing their motto Contrel DNA. But wow this is so cool. So we're finding the very wiring. Airing of the biology of life is interesting and we also know that. Maybe you can blame the man if there's been some repeat miscarriages because we can look at DNA so much that we no sperm with damage DNA may be a cause of some repeat miscarriages before throughout history. They would usually blame the women and based on knife fragility pretty sure some of at the time. The guy's shooting neither blanks or shooting crooked and well now we can measure that taught. This is just in the last year we figured all this stuff out and more and more is coming so I am becoming increasingly excited about the idea of using genomics and looking at the microbiome and looking at Aba Genetics. All at the same time. Because let's face that's kind of what life is. It's a mix of those things. It's a complex system and it's not that one is better than the other. You've gotTa have the whole picture and this is a part of the picture that we have a huge amount of details on. So that's why that's our kind of wrap up for the year on. DNA cool facts of the day. Now if that guy all excited did whether it was the idea of injecting peptides for For Making yourself ten making your brain work better resetting asleep or just waking up with kick stand all of which I just moved with the injection. I did a little while ago. I'm already feeling all excited here. You gotta ask yourself what the Heck is going to talk about is GonNa talk about sperm. Whales isn't GonNa talk about sperm which you just add As you can talk about DNA you name to talk about DNA today because today's guest is a friend scientist. Listen entrepreneur in the field of genomics who's regarded and certainly as who I regarded as one of the most innovative leaders looking at personalized functional. Genomics mix. He's won a bunch of academic and industry awards a bunch of papers and has patents in the fields of molecular diagnostics engine research and he's he's the president and Chief Scientific Officer of the DNA company and full disclosure. Here I was blown away by My analysis I've been underwhelmed by genetic analysis historically full genome sequenced and I found a twenty percent less chance of responding well to this medicine and I found out about my back hair or lack thereof. Thank you very much But it really wasn't very actionable. It was almost disappointing because I spent a lot of money. Money in the early days to get my genome and it was a monster who convinced me that there was enormous value. Here completely. Blew me away. So become an investor and adviser in in the DNA company out. Because I'm convinced that this is one of those three big pieces that we're going to need understanding. Then there's the functional genomic side he what's going on your gut bacteria and you know what's going on in the world the environment around you. which is the expert Zalm? You could call that. And the experts drives epigenetics which also can only access. What's in your functional genome? So it's like how do you do it without knowing all three. Oh biohacking is about manipulating that top level. Oh and then there's other ones are just relevant and important and this is a piece that hasn't been getting enough attention. I think it was the best person I've found who could decode actual useful value of from DNA. And everyone I know who's seen him says the same thing so welcome to the show. It's a pleasure. Thank you dave and have been thoroughly enjoying the visuals that you've given me this morning both literally and so really so that Jack that you've got going going right now let's just leave it be It's it's too funny but I really want people listening by the way. I'm doing a lot of the stuff on Youtube. There's about five hundred plus episodes on Youtube Channel. which is probably Dave Aspirin Youtube? You'll find it. It's not that bulletproof channel. We've got a bunch of the bullet videos video around Collagen in coffee and all that sort of stuff there but the other stuff where revisited be selling peptides But I am going to be talking about them so if I'm doing something and using something I might as well show it to you because I want you to see it. Even though my labs appears don't look like a coolest quite crazy scientists lab slash coffee hacker. I'm just can do anyway now when you're at Ucla you're credited with discovering one of two pathways that define drug resistant and to start out of leukemia drugs and you co authored. A paper of the year that discovered the role of the W. N. T. Four gene in the sex reversal. Tell me about the W. N. T. four gene by the way. WE'RE NOT GONNA go this deep just waiting to see how smart this guy is you know when we were looking at sex reversal. Most at that the time most of the things that you'd see that affect sexual development unsurprisingly will be the x and y chromosomes Ian Men and women so what was famous. What made the the wind four genes so important was the first non sex chromosome gene that when duplicated was responsible for complete sex reversal? So this gene being entrepreneurism Ford. So it's few things it's first and non first non sex chromosome that is involved in sexual reversal secondly duplication nations not mobile to call a sequence mutation in. This is so so important date you elucidated earlier so many people when they think about the genome and they think think about mutations they think about these sequence or letter changes maybe these things called snips single nuclear polymorphisms. In this case nothing affected the gene sequence. Wise it was just the whole gene. They hold gene was duplicated. Was the dose equivalence of the gene duplication of the gene that led to complete sex reversal so several lessons. They're about knowing. What are the type of things that affect genomic behavior? It's not just the sequence of mutation changes their copy number changes their indulge changes. Meaning just a little part of the gene was deleted duplicated or all gene was deleted or duplicated and an intelligent look at the genome has to look at all of these changes for us to truly appreciate what is happening in individual you you also and this. This fascinates me you contributed a great lead to the creation of the ability to comparative genetic screening. Things you helped to create some of that machinery early in your career. But they ask you to speak at the fiftieth anniversary of the discovery of DNA at the Human Genome Organization This is going back to two thousand three. I gotta ask you something here. You don't look like you're old enough to have done that but clearly you're doing some can anti-aging thing. I'M NOT GONNA ask you how well do are I'm just going to say what got you into. DNA So early you were. I remember I was hoping to build some of the data center infrastructure the whole to hold Craig Venter's DNA company called double twist and we had a whole floor of a data center domino's in the tech world but that was nineteen ninety nine and so even before before we could store the whole human genome data center which now it probably haven't on my phone. It's amazing indeed. So why like why. DNA all the things. You could've done. I Sean I'm classically trained as a molecular biologist my goal my the had the double major PhD but my primary focus was what producing human antibodies. Ladies and so this was the heady days of constructing what we'd call chimerical antibodies or must design unto bodies. These smart bullets as we'd call it and we needed a place to produce these onto body so you had classic models you had. For example trying to take human design that the genes for human design antibodies and and putting it into what we'd call by a reactors animal models so we would for example tried to create a transgenic bovine model so we can get the milk of that cow role to contain the human antibodies. I took a slightly different approach chickens. Believe it or not we don't get too far on his rabbit hole but chickens are so much easier is your from a from a growth perspective. You can grow hundreds of chickens in the space that you can grow or raise just a couple of cows number one number two the egg offen- cahen contains gram for gram more antibodies than any other milk vehicle in nature so the act that egg yolk is rich. Would antibodies your body. So what did we do. We made transgenic chickens. We took human antibody genes transplanted them to Hans and we allowed the hands to make these human antibodies which can be easily isolated from the yoke of the album if they know where the Disley to the DNA two things so we were doing a purely for the producing juicing antibody. That was my goal for an by the way this has led now to the whole concept that the emitted knobs and all of the smart biologic therapies of antibodies and oncological diagnostics treatments. But back then we didn't know how good we could or would get at this. Where the DNA come into Dandy came in with when I started start taking these human genes and transfer acting them into non human models? In this case Avian Hans we started realizing what happens when you just splice genes in to the existing genome. It started telling US something about the structure of the genome. That you couldn't just Willy Nilly take a gene. Even though it was a full functional units put it into an existing system not even displaced genes within the existing system. And we would see some interesting things happen. And this is where Dave the concept and I noted this to you when we first spoke the concept of thinking of DNA. Truly Dave as a language that was the key for me thus far we were thinking of DNA as the vocabulary in other words the more genes you studied ten thousand houses. Fifteen thousand twenty thousand about twenty two thousand we thought we could just simply stock these genes. Twenty two thousand of them figure out what they do study Dominic Silo Manno manner off. We go no not at all. And this is the birth of functional genomics functional. Genomics is about understanding the DNA DNA behaves and every definition like a language. It has vocabulary are either jeans but it also has grammar sentence structure picture syntax nuances. You've got to be able to reach genetic structure at the holistic level a gene on page two of your manuscript impacts the gene on page fifteen of your manuscript until unless you begin to read DNA in that intelligent language based modality -ality. You're not coming close to really the driving the jewels within DNA. So that was the real impetus so sort of like if you were to take a book and say I'm just going to search the entire book for the word the and look at how many of those there are. You're probably not gonna find what's going on and likewise you could do us a lot of old medical diagnostic technology CEO. I lit whatever it was on fire and I looked at the smoke to see what was going on. It's kind of hard to get original structure of that but that would be the electron microscope. I'm talking vote for looking at living tissues right okay so you you realize this and I think by now people listening to this guy has a brain. That's a larger than average. Have you have jeans that say that your brain is extra special. I my wife would probably disagree so I would leave it affair and take her word for it but no you know when you when you when you see something and you truly fall in love with something honestly my my love of his now become my greatest alkalies. He'll what is my greatest alkalies. He'll the nausea the nauseating sense. I get when I read the over-simplistic simplistic evaluation of genetics. I cannot bring myself to read some of the reports that are out there. That treats something as marvelous. Listen Miraculous as the human genome in these bite-size Gimmicky one gene. Little blurbs. I I think that probably there's a time and place for it but so to to your point this is a love. This is a passion of mine and my goal and my ambition is to really re educate individuals. Dave I stood what what attention people should be paying. According to their genetic makeup to their microbiome makeup on obviously to the EPA genetic factors that impinge upon not just genome by the way but the EPA genetic factors that impinge on the microbiome. They're both impinge -able by one's environment nutrition lifestyle and we probably a couple of key little sweet points. You know what I call Dave. Let's just put this as a starting starting point just really just one of those little factoid. Listen to a brilliant Medical Scientists Duck to Merman Abi at McGill University Israeli scientists scientist. MD Practicing Montreal at McGill but also researcher not getting into his work except one will not mate he said you know Dave sorry said to the audience audience percents Dave and this is what blew me away. At percent of the metabolites circulating in the human body you would think they come from your cellular reactions to human cell metabolites eighty percents of the metabolites circulating human blood. Come from the microbiome come from the MIC. So many how could we hope to even understand optimal human function. If we don't hope to understand the microbiome but here's the point it consciously consciously the microbiome because then how the body responds to all that stuff coming from. The microbiome then returns the innate genetics of the person so you so beautiful let could not have kick started this better than the way you did. It's a triangulation triangulation until we made surely put these three things together. We're not close to solving the problem. Google is going to happen. It's going to happen probably over the next ten years. I would not even a long time frame where we start getting more and more information and and companies start sharing information and research share information and we have more machine learning and all the sudden realize. There's these amazing patterns and you can walk through these things. What I'm less is confident about is getting on the experts? On which is the set of all the environmental factors that you're exposed to over the course of your life because they're limitless. It's it's like having a life sized map map of California. It would be very useful because when you enroll it'd be as big as the state and probably have more potholes but but the thing is we're going to get enough there that you can very reliably have that roadmap that says okay if you're generally avoid these lifestyle situations you're we're GonNa win but someone else you're going to do just fine in those situations so we'll be able to to environment and tuner microbiome tuning our diet and look at our genetics and then even tune our medications and other things like that and We're going to end up with An amazing way for someone who would have probably died of Alzheimer's disease at seventy to to descend walking around feeling great and feeling great full. And I'm way older than seventy just because you know we avoided hitting those potholes and do dude now. I want to also dig in on S. and I promised In the title of the show that we were talking about functional channel genomics now with the difference between that and just regular nomex which I think we just hit on there. I wanted to dig in specific on women because so much research Craig venter is actually the guy. First human genome is done a white guy and I'm not picking a crack at all. I'm also a white guy. However there has been a historical lack lack of research on women? And this if you look back at medicine the most common Guinea Pigs are actually college students and until the last thirty or so years there are way more men college students than women. So that was the sample size. You get young healthy white dudes was pretty much that and I'm pretty sure our genes build bit different because Zeev despite me injecting Molyneaux side stimulating. Hormone you have more mellow than than I do. because At actually know where you're from where are you from. I'm I'm the Caribbean Carribean. Matza originally from Trinidad but as all Caribbean islands of many Caribbean islands were admixture so many forefathers so I'm classic genetic Matz Largely Julie Having said that though more of my genetic lineage. Would you know South Asian Southeast Asian. Okay so you've got a darker skin in politics which means you handle the Caribbean way better than I do. Although I like it I just get some for all the time. But that whole different there can drive all sorts of interesting things and and there's less Southeast Asian data in all the all the not just genetic but all of the databases including antibiotics working. But if you say well let's look at southeast women in there. It's going to even lower so I wanted us to talk here and we're going to a couple interviews but I wanted us to talk specifically really about women and what you've learned about women and genetics. So we can help to correct that That balance well to to to to pivot on what you just I said I had the absolute fortune a young woman that I'd love to introduce you to Dr George Broun Val British scientists from a company called Orico and we just I. I just had the fortune of listening to her. We Co presented at a conference in California just about a week ago and she specializes on female health. She works sort of the top female athletes in the world and again just one point she said you know. Eighty percent eight zero eighty percent of the recall for drugs in the pharmaceutic space eighty percent of drugs that are recalled odd due to poor initial trials on women so in other words just to reemphasize that had every level of our medical system we have. Sean short-changed the fifty plus percent of the Human Species K. So when you take into consideration Shen number one number two when you take into consideration that the females for the lodge at least are charged with carrying the next generation. Whatever we may choose to believe in ultimately it is still going to be that female body that carries the child if she chooses to do so for the next generation? So hold on. We've we've got mothers females carrying the next generation and yet the emphasis we've placed into health. Woman has been so deplorable all so this is why we chose a DNA companies to make the female initiative offers coming out party Dave number one to the insights one can get from the very point of an intelligent functional review for example if the sex hormones they very that that very bedrock upon which defines the male and female body and everything in between but the defines the health of the female body in so many ways more than just breast development hip flare FI development. So we've done the following. We've chosen female email health as our coming out off prime minister focus and more specifically taking a functional genomics view off the mechanisms to drive Dr Hormone Health in women. Why one more piece of data Dave in North America and we believe that this is going to be rapidly. The case across the world eighty five percent of young women by the age of twenty five eighty five percent of women in North America by the twenty five has either been on the pill is on the pill in other words they are on an external hormonal. Then think about this for a moment and you know something to Georgia. Dr Bruno pointed out more are and more women on the pill. A now being led to believe that they can take the pill back. toback without even any breakthrough bleeding. So these are women who have not even had a breakthrough cycle for years on end and somehow we perceive as though that is still going to be consistent with health. And what Brunell and I really good for the Kudos for this. What she pointed out she says what we are sowing right now? This whole generation of women that are on incessant use of the pill which of course awesome. Not until I'm just saying it's use in the way that we've deployed it. We are going to be seeing a health nightmare in about ten years to come when the children children if these women and these women enter into the menopausal years premenopausal list we are facing down. The Barrel of one of the largest health concerns sounds from a population perspective. And it's going to be focused on women. I love it. They were talking about that because I just did a podcast. A couple of weeks ago specifically about the birth control pill. And how it's wrecking us and I've been aware of that breakfast as a species actually in this one but Going back to two thousand one. There's a book called sex lies and menopause From a woman whose work I actually reference in superhuman. And the idea. There's we've known about a lot of the stuff but were manipulating the epigenetics and even the behavior patterns of our species with the birth control pills. And what you're saying we didn't have enough medical data and you're saying this from a position of really deep knowledge hundred percent. Let's so let's talk about the the. DNA Company has called the female health initiative which is one of the first sets of test that you're coming out with even though you do a full functional genomics that makes now so it's like you you explain to me why I need some might. Even though my skin is so pale because vitamin D receptors is a very personalized thing. I remember you said Dave you pretty much be living on a Pacific island from the way. Your Body Handles Vitamin D. But you're not so here's how you can. You can adjust the timing in quantity of your intake to get the results you want. No one has ever been able to tell me that kind of stuff but you could have easily said that to a man versus a woman who had a similar vitamin D. Receptor genetic connectic setup. The Way I do What is what are you looking at specifically genetically? That's for women so I'm I'm going to. I thought I might have spoken about this towards the end. I'm actually going to mention it here now because of the way you introduce this entire topic one minute. This is the work of Dr Hamad. Khalili from MC Moss a note from hovered to Khalili's an MD brilliant researcher August rented all Gerald specialists at Harvard. And what he was looking at was and he is confirmed this when a young woman goes on the pill the the use of the pill. I don't know if he's define how long this needs to take place Ville but it's not those women years and years in other words just a normal use of the pill. Dramatically affects here. It comes Dave being on the pill. Conclusively this is. We're coming out of Harvard. Dr Hamad Khalili's Lab Lab being on the pill conclusively absolutely impacts the permeability of the Gut Membrane. In other words it increases is the permeability of the guts and the intestinal being on the pill. K now think of this. How many young women stay on the Pill Hill? It's becoming more and more of a practice that you're on the pill and in your birth control years then you come off the pill more often than not in time for quotes Photon quotes. Now thinking of conceiving you've got a young woman she's been on the Pill for however long she's been she's unwittingly impacting the permeability of guts. Of course if we impact the permeability of the guts we impact what is getting across the guts intestinal memory into the bloodstream. In other words things are making their way into the blood supply. That never should have been in. The blood supply things that are immune activating and showing if Dr Khalili showed exactly lead. This is what is happening. Now this is what the young woman is doing going right into deciding to become pregnant or to conceive so now. She's conceiving thieving at a time in which her gut permeability is affected. God alone nosy from micro biomass healthy or not. And then we've got to enter into. What is her innate ability to address that inflammatory atmosphere within her body? Literally because of the GUT permeability. What is her ability to address address? The Hormonal Circadian Rhythm in her body. So I just wanted to introduce the this is not just about genetics and again somewhat sear like which is classic. Dave you introduced this topic. You could not have introduced better because this this is that way but you know you just really as you often do you just nailed it so think about this. We were going to talk about the pill from the perspective of. How does the woman's innate genetics affect the we should use estrogens by the what we just introduced? It's not just at an age networks. It's not just our body metabolize estrogens but look what is happening to the body. And then we're GONNA ask the question. How does this embryo developing flipping in this uterus within a woman for whom there are all sorts of this regulated immune functions or potentially so because of everything we've just said can we expect suspects as optimal embryonic development and the answer? Anyone intelligence in this viewpoint would say certainly we are not starting off in a bet on the best possible so coming back to what we're doing this we got to pause before we gather number one. You may hear that and say oh great and these guys are against the pill like listen to the interview with Dr Sarah Hill just did a whole hour talking about the systemic effects on our species and how it's actually harming women at multiple multiple levels so full support of everyone's ability to have kids win and if they want absolutely I it I just don't I don't want to mess with people's brains there's things -iety there's depression and you are going to talk specifically about what is happening genetically from the pill here so just just be really clear. This isn't a call to say you're a bad person. If he is the pill there can be reasons and times. You WanNa use it just other birth control methods might make oh you live longer and feel better along the way it. Is You know again. Duck beautiful summary Dave. It's just take it but at least take it with the intelligence intelligence of knowing what are the implications and then you you make an informed decision and I think this is what has been deprived of the public the ability to make that informed informed decision so now. Let's get to the okay. What sort of genetics we talking about here? I think I I think the average listener has stunned the stand the men and woman the way in which we make our sex steroid hormones are progesterone. Hundreds or estrogens are remarkably similar. The cascade in other words men we have no monopoly monopoly over Andrew Johns woman. You can't make estrogen Estra. Dial and US own two primary estrogens of course as trial. When you're pregnant? You caught me estrogens until you. I make your engines so the first point here is everything we're about to say. Dave is equally applicable to men as woman or two women as a distant number one number two do the very quickly the all readers. Our listeners need to understand that the human body makes these hormones. And let's not focus back woman men in a rhythm. Why is this so important Dave because the average young woman does not realize that her estrogen levels are not the same? Every single day of recycle. The female body was not designed to be constantly under the influence of the same level of estrogens everyday for psycho. The origin the innate rhythm succeed in rhythm is one in which. Here's what happens. The female body goes through a S- occasion rhythm where she produces. progesterone thrones pregnenolone that is converted into Andrew Jans. DHEA interesting dion understand deal too strong and then we convert the testosterone. I'm into ESTRADIOL now quickly. You can imagine that if we understand that there's this Akizhjan rhythm in which some days the estrogens a higher very small window in which which you estrogen elevated and for the most part of the rest of your cycle you estrogen not elevated compare and contrast to what happens when you go on hormone replacement again just something to be mindful of now the real point that we wanna make to the public per initiative in protest. Is this different women respond to estrogen their innate. Estrogens not even being on the pill just to inmate estrogens differently. you see Dave and then just one more minutes of this. Every estrogen molecule in the female body has to be metabolised. Your estrogens of today's month this month ladies out there are not the same estrogens from your previous months in the previous month. You made estrogens you produced it. You metabolize did assume you did not conceive and you hit repeat when when you break down your estrogens your body is going to break down estrogens into three byproducts two hydroxy for hydroxy sixty four hydroxy estrogens. Every every young woman is going to do so the question is to what degree do you do each of these. Because each of these metabolites are not created unequally four hydroxy estrogen one of the three metabolites of estrogen is extremely inflammatory and has all sorts of repercussions to the human buddy. One might ask. Why are we even making it? But it is what it is. Every woman makes all three. The question she has to us is innately elite. Genetically predisposed is she more predisposed to producing more to hydroxy versus Idrissi more four hydroxy versus two hydroxy. And this is something Dave. So let's conclude on this one woman metabolize estrogens differently one woman to the next. To those metabolisms switch paths she chooses is largely genetically predisposed predetermined environment food. Lifestyle can impact that but it's largely genetically determined and then the outcome of that metabolism. Are you two hydroxy dominant. Four hydroxy dominant has completely deeply. Different health outcomes snow. We just going to ask a simple question which is going to ask. Did you know which of the two pathways three pathways your dominant full. And if you don't why not and if you don't how can you be interacting with your body without even knowing this basic factoid. That's what we're trying going to change. Now when I did my genetic testing with you I had my own genome. That I did a while back. I had a couple of consumer things. But you had me spitting a vial and send you know some of my DNA into you specifically. Is this kind of information something you can get from existing tests or is this stuff that that The best you have to send in short answer you can get most of this information from existing tests but not all and returns returns. To the fact Dave that current most rank and file good tests including twenty-three and so forth they are only looking at the spelling differences the snips however to construct the entire intelligent understanding of the royal cascade there are genes for which you're not just looking at snips you looking let's CNBC's complete deletions duplications of jeans. And those bits of information you aren't going to get from the rank and file tests that are out there okay. So so the traditional tests are going to tell you whether you spell fiber F. I. B. E. R. F. I. B. R. E. But they're not going to tell you whether you but the fiber in before you put the estrogen. An beautiful wonderful analogy okay. By the way. It's spelled E. R.. Yes I live in Canada but seriously anyway. You don't have any anger but if we do this it can be really profound right now. My Wife. Dr Lana does fertility work For people around the globe Very high touch you call week kind of stuff so she has a few clients but the UK is spending hundreds and hundreds of millions of pounds just on paramedic pause because they're finding out that they're losing billions of dollars a year in productivity and women get migraines they get all kinds of of really ruinous symptoms. That can last for only five to seven years. You're right is the kids are getting out of school. It's not a good thing and a lot of this comes down to how they handle estrogens but so we don't have the knowledge that people just run around trying all sorts of different things and is it. A progesterone issue joined Morrison. Joe Need less and then they think they've solved it but then the hormones must change cyclically throughout the months of work last week and this week I feel like I'm hung over it but I didn't get to drink. So is this something that you can get that much visibility and on just by looking at the story of DNA and and not in every biologic system. Can we say the insights ours ars profound as they are in the sex steroidal cascade and the reason so the answer is yes we can and the reason. It's a yes we kind is because it is very much. It's probably one of the best examples of a biologic cascade and again you just hit it on the head you see. How many young women you talk to them? Perry or postmenopausal supposedly. They're on a beach. RT schedule they're taking progesterone taking hundreds and estrogens in other words and many of these women. The doctors are trying. It's a little bit of a touch and feel but they're taking each of these three hormones assuming that somehow magically these three classes of homes are independent of each other and something a simple as hold on the progesterone that you taking by the way internally are going to produce engines and by the way the Andrew Johns you're taking are also independently internally going to be produced into estrogens so when you take a cocktail you better know what is the balance. You're hoping church train and by the way. What's your innate Faucet? Control how quickly are you converting the progesterone into the engines and then the android since the estrogens because McHugh might be a young woman that it's innately Estra dominant. You innately tend to cascade from progesterone pregnant loans into testosterone turn into estrogen estradiol much faster than the average female and Hugh you are going into home replacement it includes all three and you wondering why you you can't lose weight you're wondering why your watery tending you wondering why. Wait a minute all of a sudden. My cycle kicks back in off the two years of being menopausal these deep deep deep insights or something that we are working on strongly and the the the ways we can stratified the population is remarkable. All remarkable. So this means that if you had a chance to look with your DNA analysis a woman's hormone cascade this is not an EPA a genetic thing. This isn't a matter of turning a nonprofit. They have the ability to where they don't you would then recommend tuning the types and timing of the estrogens that they were taking absolutely and let's take let's take one of the most simple examples of this and you've spoken about this again just really what's off to you. Let's take something like the average young woman she's menstruating and she's going about. She's trying to lead a healthy lifestyle. She's read about Samantha. The dangers of Estra dominance dominance under extra toxicity. And what does she do she comes across this remarkable nutrient dim die in the little methane. Okay and she's read. The DIM is a Estra Quench R. E. IT suppresses the activity of the since nineteen eighty one gene otherwise known as the aroma taste gene so by suppressing the gene. What does that gene do? And it's enzyme. That is the gene that encodes the enzyme that aromatized that converts stone and Tests. Dial so she reads that by taking king some dim she can quench. She can reduce her estrogen load. Whether that's beneficial to or not is a different discussion. But here's what happens. She goes to the neutrally to company. Chubais DOC dim and here it comes. She's been strating. She takes that dim at the same level every single day as though she's taking a regular supplements without realizing that the rhythm with which she produces the estrogen in the first place behaves by rhythm so when she takes the demonte Ada for cycle nine nine per cycle versus the fifteen twenty one. Twenty three twenty five the fact if the dim on her body is completely different. This level of understanding. I'm Dave which is really where it's this is where it's at in. Really giving optimal health is completely being brushed over. Now I think a lot of people would hear this. Ah that is so overwhelming. I'm just I'm not gonNA take them like it's just not worth the trouble. Are you in a position with the panels that you're running now for women to be able to say okay based on your genetics. You should take these types of supplements on these types of days. That's that's exactly what we're getting our. That's exactly what we're doing. I determined the Astro dominance. If the Young Woman Andrew Dominance and by the way ladies out there when you hear terms extra dominance under domains if you've ever wondered the twenty two version of yourself with your roommates Collagen you've got four young women your old twenty two. You all eat the same dorm you all all sleep together exercise together. Why does one of you have your the smaller breasted? Six pack seems to be able to develop lean muscle mass without. Don't even doing half the work as the other roommates. And then why another one of you and you all swear by the fact that you caloric intake the same eating the same foods. You're exercising with the this returns to the phenomena of whether you're an android dominant. Estra dominance balanced young woman. And these things do turn turn to your genetics. So Dave yes. Once we determine the category of the John Innate genetic predisposition of the woman. And you've seen me do this many times i. I could take a look at a person without doing genetics and I can tell them. You're CYP seventeen won. The single gene converts pregnant lumped is fast but you rule matteis that converts Cyp One Thousand Nine Hundred Converts to Saas Toronto. ESTRIN is slow. We've gone by the way this comes from thousands upon thousands of profiles that we do so to conclude an answer. Your question that that is what we're doing. We first determined profile. We determined estrogen. Dominance Andrew dominance balanced we terminated. We determine the degree of extra toxicity versus not and and then we personalized with the clinician with the clinician helped clinician to better tweak what might be the supplements what might be the Best Beach. Rt routine that's what we're doing that is You said together with the physician so hot it works someone orders that they send you. I bet they ordered the thing from the DNA company obviously haven't done a female health panel when united so it was it was. It was actually kind of funny Your Business Burner. Cash A- caught me at a conference in thrusts. A kid expand this business. And I'm like okay. I have no idea where these guys are going to try and clone me or not But when I got on the phone with you I was. Oh this guy's like neo from the Matrix Zeros and ones but you see that with jeans just when people walk around. So I didn't go through the the formal process but do you give the like a lab. Just you give give it to the person's Dr do you give it to them directly. What if they want to go to the doctor at an how does not work so you know? We largely work with healthcare healthcare providers. Because we always want to make sure that at least at some point there is someone overlooking the bigger picture of the person so just to be clear consumers can come directly to us. But what do we we have. We then have a whole battalion of internal trained clinician. So you either. We either work with your clinician in several categories of conditions that we work with all all our internal clinicians when we make decisions such as profound decisions. What version of the pill again? Not about whether you are aren't but maybe what version of the pill that you should be on beach. Rt What tweak would be better for you so with those things we work directly either or internal clinicians or the clinician involved with the the individual. Okay so there are tens of thousands of positions. I who listened to bulletproof radio I was just at the American Academy of anti-aging medicine and and there's a lot of fans it was it was it was neat Just to kind of walk down a walk down the hallway and and meet some of them early so what I would what I I guess so. Doctors can reach out directly to the DNA company if they WANNA have in. It's essentially another lab tests. They could order. Okay got it. It's it's another lab test but we really do a training because the key we train them directly should have asked you this before the show so I could just say it but anyway And then for for a woman who wants to order the men can order the other stuff on the side but specifically to this panel Woman's going to order it order directly she can take the results into her Own Position if she wants to or she can work with the physician that you have on staff or that essentially announced like you do these people you've trained to understand understand what's the story of DNA versus the words in it. Okay exactly now. Let's talk about those three types of women You had blondes Brunettes in red hedge. I'm sorry you're talking about balanced versus John. I want to go into more detail there because I think that that's profound. Let's talk about the androgen dominant woman. Do you talked about. Her in college eats so if she wants lean reps and her friends are jealous of her. What's the downside of being that woman? What do you when they're not working in your favor? Indeed so of course it's a spectrum and so the more should be cup she goes to. That's Andrew Dominance. What is happening here? She's the Young Woman that her circadian rhythm. She efficiently officiant converts for Pregnenolone progesterone into Andrew. Johns because of the speed of precip seventeen one. She also converts testosterone because of SR thirty five eighty two into that Oh that one molecule of DG's worth six molecules of testosterone. So she's lighting up on the androgen side of the scale gale but she has the slow conversion of distortion into estrogen. So it's not that she's not a young woman. It's just that the balance she's skewed to Androgen adrain dominance and it is or vertically noticeable in her phenotype up to and including Dave simple things these dominant women are the women that go through the entire lives. I don't WanNa be pedestrian industry. But important things. She almost never have cellulite. She will not suffered largely speaking from stretch. Marks as leasing. uh-huh I only say that because I have stretch marks and it's an it's an woman asked me. How do you know that about me? Explain this okay so the benefits. It's the benefits as they are the ill or the counter the counters these young woman because they already so android dominant. Mild the the stresses in life whether it be athleticism or actually motion stresses can quickly put these under dominant woman into missing their cycle. Why lighting because they already not generally creating much of this Acadian arc to estrogen production because they're under dominant and by the way that oh important progesterone for gesture ruined it? Produces to stall stone also produces cortisol so when this young woman introduces anything that is Cortisol. Inducing she's further further draining away from the PT to e progesterone estrogen. You will find that. These andhra dominant females. Many of whom might be athletic. Many of these female athletes can go months without having a cycle. And so there are some of these some of the downfalls another downfall is this the prolonged predominance of D. H. dihydrotestosterone which men and women produce. That's that testosterone onto stone. Seems to be one of the confounding. Factors Capriccio predisposing and women poly cystic Ovarian Syndrome. So there a couple of things that we have to watch out for fixing circadian rhythm not too much stress and obviously there's a lot of nutritional and environmental things for issues Mutual Lana Had P. C. O. S.. When I met her she was infertile? and that was why I wrote the the better baby book with her and did all that research for it and did all the cooking for it. Because I I know you can reverse that stuff epidemiologically at least in some cases. And Okay what's what is that. phenotype going to do at menopause. So a couple of things. These women by the way tend to not have in wool that any man should should ever tell the woman they know what menopause is like but all things equal. These young women do not have the overt menopause as many others. Because what does menopause at the end of the day. It is not dropped between what was normative cycle cyclical psychological estrogen to the then postmenopausal. Estrogen these women. There Delta values already quite low. And it's just a you know we can learn by societies. Look the Han Chinese population more Han Chinese both men and women are more Andrew Dominant that classic pheno type of the Han Chinese young women who is you know phenotype. We don't really have to describe them. But I think everyone understands that smaller breasted lean body type and amongst the population. The concept really debilitating. Menopause is rare. It's rare because that Delta drop so in other words that summarize a young woman who is Andhra dominant tends to have a much less. They don't have the menopause that eight New York City versus the previously. Estra dominant woman. She's lived her life with high levels of Circadian Monthly estrogens. Menopause comes along her estrogen plummets and now she's dealing without adjustment. So yes you can always predict. You could quite nicely predict what menopause the police and the symptoms of menopause will be to these young women okay. Let's talk about someone who is at the end of the spectrum Someone estrogen dominant. What is he like in college? She's the one who's had puffiness the most. I'm guessing she you know she's the she's classically. The more courageous young woman by and she can be up slightly absolutely healthy absolutely strong absolutely healthy body weight but she will observe. She'll observe the body type right because what is Davis backup book surprises. It's not you obviously a not your community likely but how many people don't even know what estrogens do estrogen and actually the sex hormones are what if the most potent Dini transcription molecules or agents into body estrogens buying to sells through the estrogen. Receptor is not complex than moves from the the cell membrane through the site of plaza them into the nucleus and turns on and off gene so in other words estrogens origins impact the way cells. Behave so when you take young woman. When she was eight years old all four of these roommates they all oh look similarly no breast development? They look in the boys girls. Same Body type now. If you had a magic scanner Dave and you scanned these young woman an for where are the estrogen receptors and the density of estrogen receptors the to Susan their body that more estrogen sensitive. You put that on a scale of white pink to read what you would find in. The Young Woman's body at the age of Eight is her whole body is pink pink in other words all of the cells body estrogen sensitive but sutin zones in her body are redder the breasts zone. The HIP zone the back of the fault zone and so so meaning. Those cells are more estrogen sensitive now. The estrogen dominance young woman will be the woman that when she hits Hermano the parts of her body that estrogen sensitive respond to the estrogen the highest origins much muscle much more so than her colleagues. So she's going to be the motivation young woman. She's going to be the young woman that she can go to the gym. She can be healthy and her weight. She can be strong but she's not going to get that straightened. It's a muscle that cuts that six pack as easily as under dominant colleague. Okay and it's probably not healthy. Look for anyone. The looking like a hunted hunted animal. Probably it looks pretty good but in terms of longevity that might not be a really good strategy but in terms of being a fitness competitor. Yeah you do it but do it for a week. Don't try to do it every all the time. Brilliant and now how is an estrogen. Dominant woman going to to face PREMENOPAUSAL Menopause K.. So key factors here. Two things. Estra dominance should not be confused with Estra toxicity acidity. So in other words a woman can be skewed Estra dominance but then when her body does see the estrogens she's perfectly healthy into issue. METABOLIZE is those estrogens. I E that her body's metabolising the estrogens preferentially down the two hydroxy pathway. Her menthylatim is healthy. Because that's how we get rid of these estrogen intermediates through methylation her detox. Panelists healthy all year dietrick. So you can have a young woman who was extra dominance and perfectly perfectly out of the woods of any estrogen concern. You can have a young woman whose unjust dominance but the little Estrin she produces will tend to go out on the naughty for hydroxy toxic powerfully. By the way those are the women that suffer the most when they go on the pill you see those under a dominant but Estra toxic young woman or the woman that outside of the pill they innately don't produce as much estrogen so that extra toxicity is being camouflaged. They go on the pill they uncover their -letes and Estra toxicity physiology and all hell breaks loose just FYI succumbing to the extra astro dominant young woman going into menopause. We must then ask the question. What is through strategic potential? And why is this so important Dave. When does the preponderance at a societal population basis? When is the preponderance of breast cancer? Kick in Peri Menopausal Menopausal y ladies out there where this is so critically important you heard from David deposits. Let me reemphasize this during your menstrual years. You're estrogen of being metabolised. I used deliver in other words. That process will you break down your estrogens. You may not be making naughty intermediates. That's happening in your liver and your liver is designed and to handle this degree of toxicity to a degree when you hit peri menopause. Your estrogen metabolism begins to take place in your adipose fatty tissues including your breasts. So now if you happen to be that extra toxic female and you did not know this. These are the women Dave and by the when is the body producing. These estrogen. METABOLITES that we're talking about all women but when is it happening about five days prior to their cycle so when you're that young woman five days prior to your cycle you start to get that extra nipple sensitivity breast tenderness. This is a sign that your body is starting to breakdown estrogens in Brussels and you. A bio accumulating more of the inflammatory estrogen metabolites. So these are the things we WANNA watch out for at the border of menstruating and menopause. And do you tell women who do the panel with you what to take to avoid those those things indeed it's guidance and again work with the coalition but absolutely that's the point of it. Yes so there's supplements and or Pharmaceuticals that you take to blunt those effects because now we understand how your body genetically handles estrogens. So when the spike happens you still have normal cycling. But you don't have the pain and the annoyance indeed and you think I mean obviously I haven't ever Had that ministered I'm a guy but every guy who's lived with a woman knows there are times when it can be just really a huge painful irritating frustrating thing For the woman and for all the people around him sometimes Dave point really quickly. Let's let's just consider to this. The estrogen metabolites. These twos and fours hydroxy estrogens. They are what we call. Chemicals type of molecule and body called acoustical article. What's the other group of capitals into body newer chemicals so it is unsurprising that the individuality which a young woman metabolisms estrogens children's into two hydroxy versus full hydroxy four hydroxy being more inflammatory? Those molecules remarkably mimic and look like the newer chemicals that impact mood so. It's not surprising that we can stocks then begin predicting and helping young women understand. Why are the mood? Changes through their cycle particularly in those days winding up to their flow winding up to the administration. It's remarkable Dave what you can start individually visually recognizing and treating when you understood intelligently. What's happening in the body? This is mind blowing stuff and I was. I was pretty skeptical when I first got a DNA test from from you the DNA company but as my friend. Joe Polish Dave. You should you should give. This is a try. I learned stuff. I wouldn't possibly believe 'cause I I have a stack of DNA results. That have never told me squat so so when I got on the phone with you and you walk through kind of like you just did for for listeners. But you walk through my specific story completely. Blew Me Away and oh I think the work you're doing here around. Women is one of the most important things you can do because understanding your own customs sex hormone perspective and then what to do about it the what to do about it part can sometimes be a shot in the dark in the conversation we had earlier about birth control pills and what it does to that depending on your system is also critically important and so far on the show a doctor Jillian brightens been on a couple of times and Dr Sorry Hill was just on talking specifically about birth control pills. NTSB Wiley was on as well and the line is I I I would love for for that to just work and also there are. People were saying there's birth control pills for guys that they're experimenting with look. I'm not hacking my hormones to that level. I'm happy to hack my hormones. I take take US Australian and it's improved my life dramatically but I- tuned it with the doctor and I don't take crazy levels and I do it in a way that that is supportive live and increases my health instead of taking it away and and so I I would. I would encourage people to check out the test. The DNA company DOT COM. And as I mentioned before guys I am an advisor. I'm an investor. I'm helping Helping to bring this message to the world so when I care a lot about something I either start a company but neither does it. I invented or I support people who are doing something really different and An interesting so I would say you've definitely only done just that you have an amazing body working career but this new stuff is really important. This is my legacy Dave. All of the things I've done. Actually someone asks me what. What is the legacy what? What do you want to leave behind? And I did a lot of working on college and Childhood Development but it is this the real ability to excess the operating manual of the human being and do something with a Dave. That's what I want to be my legacy. Well IT'S A. It's a good legacy that you're leaving and it's it's it's it's it's hard to explain. I think the closest thing is like neo from the Matrix. There's the scene where he finally realized that and he's looking around. He's looking at hallway and everything Zeros and ones falling thing. I know functional movement. People you walk in there like Oh so what's wrong with your left ankle pain in your writing and and like what. How did you know that I just the Guy Walking in the door and you're the same way but you're looking at someone's jeans you know it's funny? My younger son introduced me to a young woman that he's interested in and the first thing I I looked at it said Oh boy this young woman has pcs. I obviously didn't ask but all the physiologic signs of the New Right off the bat. This is a young woman that is you must be the worst because you like. I'm so sorry son but her phenotype is not compatible with yours. You need to find another girlfriend. I mean have you ever said that It is pretty got it because of course I know my children's Gino type and I know what's GonNa the happened when they're sitting combinations for their children and so on so forth absolutely at. You are an expert in that and and this isn't something that that I planned to you about But if I were going to have you back on the show when you come back on the show I wanNA talk about designer babies and they'll get choosing proper mate and some things like that because there's so much there's a whole episode about guys hormones about cardiovascular risk factors in men versus women and genetics and you are top of the game for those things so it's part I'm not going to die from the four killers from superhuman. I'm taking your advice and in my own my own practice and that said though I i WanNa talk about that okay. How conscious do we need to be about choosing a mates and some interesting technology coming our way that I have a feeling you're going to know about and so let's let's say some of our largest intended investors wanted to use this technology for dating apps on just you you know I? I can't wait to talk about that honest if I was dating. You know earlier in life and you could say you know what I'm going to present you with a list of people who would be emotionally compatible with you because you have to outside and genetically compatible with you. I'm pretty sure they're going to smell better and look hotter to me because that's how Oh biology works and I'm gonNA smell better look to them so it's just going to be a better date and if it turns out to be more than a date in it's a lifelong relationship having a genetic compatibility so you're less likely to have kids with all the the genetic defects that happened somewhat randomly. Now that's A. Ah Good so I'd wow I I you know I. I must admit that I know embraced the knowledge much much more than I did. I was obviously the ethics if it the responsibilities of it and we'll get to that when we come back on the show but knowledge is empowering to the degree that you know intelligently what to do about it and I. I think we're getting to that point. Dave where with the right team with the right insights. We can do some amazing things with what we have we can. We can enhance freedom to so then. If you're with someone who say we're in love. We're we like this and we know were genetically. We've got some issues there probably hackel in in the year. That's that's the point actually right there. It's not the negativities. Liberty of the positivity that we're looking well you're doing some of the most cutting edge useful genetic research out there and I'm super happy him a part of the DNA company. And that I you know I I get access to you and your knowledge and your team and I'm happy that Lana does as well as well. Els My kids so we will have you back on the show in very short order in the meantime people go to the DNA company DOT COM. And I don't think we set up any sort of bulletproof radio thing. There's the Dini company DOT COM. Check it out. It'll be a it'll be worth your under national or thank you. It's a pleasure sir. You've probably noticed that. I mentioned a lot of new biohacking and anti-aging technologies on the show and they love it that I get to see share. Almost every new thing that comes out and some of the companies that are really upgrade my life and I walked the talk by partying with her investing testing in some of the companies that I really love bulletproof radio was created in his hosted by Dave asprey and the podcast assistant has hamson research is provided by Darcy. himes an all technical aspects are handled by our podcast mastermind Brock Armstrong his podcast information purposes only statements and views expressed on this podcast. Not Medical advice is podcast. including including Dave asprey in the producers disclaim responsibility for any possible adverse effects from the use of information contained herein. Opinions of guests are their own in. This podcast is not endorser. 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