35 Burst results for "19 Vaccine"
Curevac’s Covid-19 Vaccine Disappoints in Clinical Trial
"All right. Let's kick off the podcast with a kind of a dish on the week's news and we should definitely start with cure vac Meg what happened to curevac co vaccine. Yes this was hugely surprising wednesday afternoon. The news came of the company's results from their late stage. Clinical trial of forty thousand participants of another rene vaccine and of course with the success of madeira advisor. The expectations were very high that the efficacy would be very strong and it was forty seven percent now. The company cited a large number of variants. That were in the trial though. Wasn't clear the exact impact of those various on the efficacy. And there's some speculation that it could be the differences in the vaccine from modernize and visor biotechs damian. You looked into this pretty deeply. Yes so not all. Mr nays are created. I shouldn't say equally the same so pfizer and medina both use an approach to work in a tiny modification that is meant to basically avoid the immune system from attacking the marnie strand that you insert curevac used an unmodified marnie for its vaccine and the company's reasoning was you know for an mri therapeutic. Yes sure you'd want to avoid an immune system reaction but for a vaccine an immune system reaction is kind of the name of the game and so that was kind of their thesis going into it but as a result of using the unmodified marnie. They used a smaller dose than pfizer. Madrid Which most likely was to avoid any kind of too much of an immune reaction and so a lot of people. Curevac didn't say this and they haven't provided really enough detail on the data in question for us to really dig in but there is a theory going around out there that enserch of this kind of goldilocks dose of this unmodified. Marta they might have had simply too weak of a vaccine to get the kind of efficacy numbers that we've seen from the pfizer vaccines.
Biden Calls Communist China 'Our Partner'
"You signed onto the G seven communique. That said you G seven. We're calling on China to open up to let the investigators in. But China basically says they don't want to be interfered with anymore. So what happens now? The impact the world's attitude toward China. As it develops. China is trying very hard. To project yourself as a responsible And very, very forthcoming nation. That they have found very hard to talk about how they're taking and helping the world in terms of Covid 19 vaccines. They're trying very hard. Look certain things you don't have to explain. To the people of the world. They see the results. You know what's remarkable. I'm telling you. I heard that cleanly for the first time there, Jim, would you agree? It's even worse than I thought. I got a double Mike and Jim both. It's a It's a three for right there. It's not meatloaf. Two out of three ain't paid three out of three. That's even worse. No, I'm serious doing their best. I mean, that's insane to be some kind of responsible partner. Are you crazy? Did you eat? What is it?
899 People Got Expired Vaccine Doses at Times Square Site
"Hundreds of New Yorkers are learning. They got expired doses of the Pfizer Covid 19 vaccine, the city's health department confirmed almost 900 people got expired shots at a pop up site in Times Square, and officials are now notifying those involved and telling them they need to get another shot as soon as
Novavax Says Its COVID-19 Vaccine is "Highly Effective"
"Novavax today reported late stage data from its US based clinical trial showing its vaccine is more than 90% effective against Covid 19 across a variety of variants of the virus. The study of nearly 30,000 volunteers in the U. S and Mexico puts Novavax on track to file for emergency authorization this
Novavax Offers the U.S. A Fourth Strong Covid-19 Vaccine
"Novavax is planning to apply for emergency use authorization this summer in clinical trials, The company says it's too shot dose is proven to be 100% effective against serious or potentially deadly cases of
G7 Leaders Pledge a Billion COVID-19 Vaccines to Poorer Countries
"Leaders are wrapping up the G seven. I'm Pam Couso Fox news and they're making some big promises. According to a draft communique, the group of seven is pledging to vaccinate the world against the coronavirus leaders will also invest in a massive infrastructure plan for the developing world to rival China and will increase climate contributions to help poorer nations. From Britain. President Biden will head to Brussels for a NATO summit on Wednesday, he'll be in Geneva for a face to face with Russian leader Vladimir Putin. In an interview with NBC, Putin described Biden as stable. He called former president Trump colorful. It has been announced that Biden will not do a joint presser with Putin as president Trump Had done. They're going to try to control the message, Fox says Greg Palkot at Britain's Windsor Castle, where the president will have tea with the
Biden and G7 Leaders to Commit to Donating 1 Billion COVID-19 Vaccines
"Continues in England. President Biden and the leaders of six other nations vowed to take joint action against Covid 19 and all future outbreaks. Shooting in
COVID-19 Vaccine: Columbus Offering $100 to Residents
"Columbus City Council votes Monday night on a proposal to pay Columbus residents $100 cash when they're fully vaccinated for coronavirus. Only people vaccinated after Monday would be eligible for those cash payouts, which some are calling vaccine
U.S. To Donate 500 Million Doses to Global COVID-19 Vaccine Supply
"Speaking at the g. Seven summit on thursday president biden said this quote the united states will purchase a half a billion doses of pfizer cove nineteen vaccine to donate to nearly one hundred nations. That are in dire need in the fight against this pandemic. that's a historic step the largest single purchase and donation of covid nineteen vaccines by any single country. Ever unquote He said these vaccines will start being shipped in august as quickly as they can be manufactured. Two hundred million doses To be delivered this year with another three hundred million in the first half of twenty twenty two bill what what do you make this As a foreign policy initiative exercise in soft power. I think it's it's great. I'm glad the biden administration is doing this. Look at the position. we're in now. Just as opposed to a few months now that we're now in the position to donate these extra vaccines. I think it also shows is our editorial points out that We can help the world with their vaccinations without having to suspend intellectual property rights. And so for some of the more dubious ways that they want to do it. So i think there are a few questions you could ask about the distribution and how you know how we're going to choose but it it's it's a it's a great move it you know. It speaks to the best of america and we can do it in. It's it's it's it's a great thing for the world
G7 Leaders Expected to Commit to Donating 1 Billion COVID-19 Vaccines
"Are expected to commit to sharing at least a billion coronavirus vaccine doses with the world at their summit today, after doses would come from the U. S, which committed to such a move earlier this week, Another 100 million would come from the UK
FDA Extends Johnson & Johnson COVID-19 Vaccine Expiration Date
"And johnson vaccine stays fresher longer. The fda extended the expiration date on millions of doses of that vaccine by six weeks the agency determined. The shots will remain safe and effective for four and a half months up from the original three months and that should help with covid vaccine. Waste
G7 Expected to Donate 1 Billion COVID-19 Vaccine Doses to Poorer Countries
"The group of seven leaders meeting in southwest England are pledging to share one billion doses of coronavirus vaccines with the world's poorer nations at the G. seven summit British prime minister Boris Johnson has announced the seven wealthiest countries in the world will share a billion doses of vaccines with places like Africa Asia south and Central America and others trying to speed up the global pandemic recovery it follows president Joe Biden's announcement that the US would donate five hundred million doses of the Fizer vaccine over the next year we're gonna help lead the world out of this pandemic working along side our global partners Britain has pledged one hundred million doses previously Germany had promised thirty million the British prime minister says these pledges meaning that they can vaccinate the world by the end of next year and then build back better from corona virus I'm Jackie Quinn
CDC Looking Into Reports of COVID-19 Vaccine and Heart Inflammation in Teens
"Advisors is looking into whether there's a link between the coronavirus vaccine and young people developing heart inflammation. The CDC's says it's noticed reports of myocarditis, mostly in teenagers and young adults after they received the second dose of vaccine, the agency stresses. The cases are very rare and most people quickly recover. Homo news time 3
Biden Announces U.S. New Global Vaccine Efforts
"Biden. In the UK tonight confirming during his visit there that the U. S plans to buy 500 million Pfizer covid vaccines with a plan to distribute them around the world. President Biden announcing that the U. S. Will donate half a billion doses of fighters coded 19 vaccine to Kovacs, the global immunization effort America Will be the arsenal of vaccines and our fight against global Covid 19, just as America was the arsenal of democracy during World War two. The 500 million doses will start shipping out this August and go to 92 countries, including some of the world's poorest nations. Karen Travers, ABC News traveling with the president in Cornwall, England.
Moderna Asks FDA to Clear COVID-19 Vaccine for Adolescents 12 to 17
"Wu Moderna is asking the FDA to clear its covid vaccine for 12 to 17 year olds. The drugmaker has filed for emergency use authorization, setting a study of more than 3700 adolescents. Currently, fighters vaccine is the only one approved for that age group in the
Africa Desperately Short of COVID-19 Vaccine
"In the global race to vaccinate people against Kobe that nineteen Africa's tragically at the back of the pack in South Africa with the continent's most robust economy only zero point eight percent of the population is fully vaccinated in Nigeria it's zero point one percent Kenya is even lower underground a has recalled does is from rural areas because it doesn't have nearly enough to fight outbreaks in big cities the content of one point three billion people is facing a severe shortage of vaccine at the same time a new wave of infections is rising across Africa I'm sorry a shockingly
Moderna & Pfizer COVID-19 Vaccines May Soon Be Available for Kids
"Have Covid vaccines available for kids as young as five. In the coming months. The Cambridge drugmaker as well as Pfizer, both working on clinical trials in hopes of delivering those vaccines to infants as young as six months old as well following demand for
Zhou Yusen Filed for Vaccine Patent Before COVID-19 Outbreak
"Up dead. I want you to go to this piece. Everyone, please. You can check it out my newsletter or you can just go right to it. By my friend Kyle Becker and Becker News. Here. Is that the headline in the piece? China game Wuhan lab secret military activity. Led to a February 2020 covid vaccine, patent report finds Again. If you were going to make a bio weapon, you damn well better have a vaccine first. Here's the first quote from the peace and it's quoting some research by an Australian newspaper called the Weekend Australian. It says, quote there talking about this woman Zhao use N It, says Zhao, who conducted the research in conjunction with the Wuhan Institute, University of Minnesota and the New York Blood Center, was the first to file a patent for a covid neck Covid 19 vaccine on February 24th of last year. According to documents obtained by the weekend. Australian This was only five weeks after China admitted there was a human to human transmission of the virus. What were they doing? Building a vaccine and spending all this money on a virus that they had said Don't worry. There's no human to human transmission. Does that make any sense to you only if they were lying. The holder of the patent. The piece goes on his striking Zhao use end is listed as the lead inventor on the patent application lodged by the Institute of Military Medicine Academy of Military Sciences of the People's Liberation Army of China. The report states folks again When are these media types going to remove their craniums from their rectums? And say, Holy Moses? This sounds
"19 vaccine" Discussed on This is Why
"It's <Speech_Female> <SpeakerChange> <Speech_Male> <Speech_Music_Male> <Silence> <Advertisement> <Speech_Music_Female> <Music> not just sort <Speech_Female> of the few of us that <Speech_Female> have been working in the space <Speech_Female> for years. Raising the <Speech_Female> issue <SpeakerChange> you <Speech_Female> were hearing from <Speech_Female> all sorts of audiences <Speech_Female> you know what <Speech_Female> about pregnant women. When <Speech_Female> are we going to have <SpeakerChange> the data on them. <Speech_Female> Are they going to be eligible <Speech_Female> <Speech_Female> <Speech_Female> Studies as <Speech_Female> well as two <SpeakerChange> to receive <Speech_Female> these vaccines <Speech_Female> so Yeah <Speech_Female> it's interesting. <Speech_Female> When we started <Speech_Female> the work in the <Speech_Female> face. <Speech_Female> A colleague <Speech_Female> said you know <Speech_Female> we know this <Speech_Female> is really important. But i <Speech_Female> feel like you just can't be <Speech_Female> a big enough drum <Speech_Female> <Speech_Female> to get movement <Speech_Female> and now <Speech_Female> i feel like there's a pretty <Speech_Female> loud and <Speech_Female> diverse <Speech_Female> percussion. So <Speech_Female> it's a. <Speech_Female> It's <SpeakerChange> nice to <Speech_Female> know that there is a <Speech_Female> large <Speech_Female> coalition of people that <Speech_Female> recognize the importance <Speech_Female> of this work and <Speech_Female> And i think <SpeakerChange> that's where <Speech_Male> we're really start to see continued <Speech_Male> change and <Speech_Male> carry on your orchestra <Speech_Male> metaphor. You just <Speech_Male> need conductors to <Speech_Male> to <Speech_Male> to waive their wand <Speech_Male> to make it happen. <SpeakerChange> <Speech_Music_Male> I'm <Speech_Male> <Speech_Music_Male> if <Speech_Male> <SpeakerChange> if <Speech_Male> maybe not. 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Where <Speech_Male> should pregnant women. <Speech_Male> Sit <Speech_Male> in your opinion <Speech_Male> in terms <Speech_Male> of of of rollouts <Speech_Male> here in canada <Speech_Male> <Speech_Male> We're focusing on <Speech_Male> people in in long <Speech_Male> term care homes the very <Speech_Male> elderly and <Speech_Male> healthcare workers <Speech_Male> where <Speech_Male> where should <Speech_Male> pregnant women <SpeakerChange> sits <Speech_Female> in that lineup. <Speech_Female> <Speech_Female> These these are really <Speech_Female> challenging questions <Speech_Female> in terms of how to prioritize <Speech_Female> limited <Speech_Female> doses of vaccine <Speech_Female> <Speech_Female> Again <Speech_Female> <Advertisement> i think. <SpeakerChange> Many <Silence> <Advertisement> <Speech_Female> <Advertisement> <Speech_Female> jurisdictions are <Speech_Female> trying to prioritize <Speech_Female> those who face the <Speech_Female> absolute greatest <Speech_Female> risk of mortality <Speech_Female> and morbidity <Speech_Female> as well as those <Speech_Female> who are really driving <Speech_Female> the response efforts <Speech_Female> on the front line. <Speech_Female> And i <Speech_Female> think that's right. <Speech_Female> <Silence> <SpeakerChange> I think <Speech_Female> in terms <Speech_Female> of pregnant women. I would <Speech_Female> say probably given <Speech_Female> that. They are at greater <Speech_Female> risk than non <Speech_Female> pregnant adults. They <Speech_Music_Female> should be <Speech_Female> earlier on <Speech_Female> Than <Speech_Female> the general adult population <Speech_Female> <Speech_Female> But again you <Speech_Female> know as supply increases <Speech_Female> you know. <Speech_Female> There's a lot of decisions <Speech_Female> have to go in <Speech_Female> and a lot of morally relevant <Speech_Female> factors <Speech_Female> to try and prioritize <Speech_Music_Female> those at the front <Speech_Female> What's what's been <Speech_Female> really great. <Speech_Female> Both in the us and canada <Speech_Female> at least is that <Speech_Female> you know as <Speech_Female> Maxine <Speech_Female> have been ruled out <Speech_Female> the workforce to <Speech_Female> particularly the health <Speech_Female> workforce. <Speech_Female> I'm that there have been <Speech_Female> many women <Speech_Female> who are part of that. <Speech_Female> Workforce who have enthusiastically <Speech_Female> signed <Speech_Female> up and said yes absolutely. <Speech_Female> Please <Speech_Female> vaccinate me. So <Speech_Female> it's really great to see <Speech_Female> that. They have not been excluded <Speech_Female> from those efforts <Speech_Female> that <SpeakerChange> were eligible <Speech_Male> to to get acclimated <Speech_Male> corallium <Speech_Male> magin that <Speech_Male> pregnancy <Speech_Male> and parenthood <Speech_Male> is fraught with <Speech_Male> worry and concern. <Speech_Male> How <Speech_Male> should this news <Speech_Male> from companies <Speech_Male> like pfizer and biontech <Speech_Male> be seen <Speech_Male> by pregnant women <Speech_Male> by people who are <Speech_Male> either considering <Speech_Female> or <SpeakerChange> currently <Speech_Female> pregnant. I <Speech_Female> think this is good news. <Speech_Female>
"19 vaccine" Discussed on The World Next Week
"We need to be modifying our vaccines example new variants of this virus. You really are merging and take hold that might impact the benefits of the vaccine right now. We don't believe that's the case. But we need to be monitoring that so so this notion of monitoring. Is you know at the individual patient level but it's also much more significantly at the population level to really understand trends in a and potentially emerging issues or concerns. And if you refuse it wouldn't be considered a vaccine adverse event but it would be a concern. I think in the context of the health care delivery and public health system. And you know hopefully people that have questions about the vaccines will have an opportunity to talk to people that are knowledge about knowledgeable about the vaccines and people with whom they have a relationship and have trust and confidence As as dr johnson was saying it's very important that people can go to individuals that they trust to know To get the information they need us there. There are a lot of comments in the chat are questions about supply and demand and the demand is outpacing. The supply do do we have a do a number on how many doses federal government still has an what's been sent out to the states or is that still murky. Sadly it's very it's very opaque in. That's part of the problem clearly at the get go. There was a disconnect that didn't really make sense in partly represented. I think core Communication about what was happening but also perhaps lags in reporting on vaccinations cetera appeared. That more vaccine had gone out than was actually being used in terms of administration. I think as we've already heard today Those who are on the ground trying to deliver vaccine are feeling frustrated that they don't have the supply they actually need But i i'm not in a position no longer being government to really Clarify what the existing Supplies are but it's a critically important question. And maybe then as part of his his activities has a better You know a sense of where we are. I decide to deduction hampers comment said a At least what. I'm hearing just especially in conversations with a main clinical providers that are that are operationalizing. Vaccinations so cvs walgreens and a few other enemies that day. It to your point. Where we're very much supply constrained there's been about Just one hundred and fifty thousand individuals including myself. A one of the lucky wants to get the two so far Eh believe there's about twenty seven million doses out there a third of which have been administered at least one dose. One dose has been administered to f- about a little less than ten million individuals We're hearing that doctrine. Hamburg's mentioned the johnson and johnson vaccine. That's likely gonna get Emergency use authorization sometime in early february. We anticipate which is going to dramatically make supply chain distribution a lot easier. Just because it's a vaccine that requires one dose and can be transported in ambient temperatures room temperature and then stored in just a in any typical refrigerator. That minority exists at a at a healthcare Establishment to make a lot of things easier but unfortunately it looks like they are supply supply constrain. We're anticipating hundred million doses by sometime In the late spring and it looks like that won't happen until early to late june But there is expected to be more doses coming from pfizer madeira. It's unclear how many but there is a it. Looks like there's not going to be any issues with getting the second dose in more people's arms since that since now the second goes is not being withheld at the actual numbers though are not clear. I will finally say At least the employees that i'm charged to protect their health and safety grocery store workers couriers. You name it. Every state right now has different rules and so virginia. For example it's following a set guidelines to not Versus new york state washington state for example. They're doing things a bit differently. And i soak actually not having fifty different approaches in the by administration hopefully being able to coax all fifty states to admit to follow a sip guidelines will make things a lot easier when it comes to vaccine distribution transparency following tracking. Who has who has not gotten The vaccine because right. Now if it's one thing to say at one cohort should get the vaccine grocery store workers. But it's another thing to say well. Virginia's only gonna give grocery store workers the vaccine if they're a buck fifty but washington states in the grocery store workers that accede regardless of age limitations is just gets really confusing and lobbying bodies. That are trying to advocate for these various different cohorts. It gets gets complicated quickly. So i think fifty states need to align on sept guidelines. Ideally i'm there couple of questions on the science of it if you have any insight into the research underway for vaccine. The vaccine were children under sixteen As well as the effects on women pregnant women can. I'm simplifying the question. Sorry i want to keep it short. But you i guess those and i think the right person probably to answer it. Which was that when the studies were. initially structured. certain important subpopulations weren't included in the studies and that included children and Pregnant women also The significantly immune compromise but those are all very important populations in terms of our overall management of the pandemic. So what we need to be doing now and this work is going forward is is Go down more specifically into those subpopulations to ask and answer these important questions. And that doesn't mean doing huge elaborate studies with forty thousand people like we went through for this initial authorization but it does mean doing some what we think of as the the sort of basic safety and dosing because for example with kids. It's likely you're going to want to use a lower dose and then bridging studies feel comfortable. Moving them into broader uptaken usage of vaccine. Now.
"19 vaccine" Discussed on CFR On the Record
"All try to read the slowly. You need a scientific background a basis you need to think in terms of the clinical the logistical as just mentioned The community dig in terms of human rights again. Churches play can play a role in that the behavioral communication facets on on undisturbed distribution of healthcare. So those are the seventy really need to look at. Thank you okay. Let's go to representative power good afternoon. Everyone thank you for taking my question. My name is diane. And i am a new hampshire state representative and my question has three parts. Dr hamburg stated the necessity of tracking people who received the vaccine in an effort to qualify the vaccine's efficacy duration of protection as well as any potential adverse reactions. Constituents of mine are concerned about privacy. So my questions are as follows. I'd like to understand what body is the clearinghouse for this information. Would it be the cdc to what types of patient data will be required to be collected and by whom would it be at the state level federal level in how will that information be dispersed and three I'd like to understand. Is the refusal to receive the vaccine with that be defined as a vaccine event and with this be Recorded thank you well. That sounds like a question that i should at least start with you know it is routine that vaccines are monitored in the real world in order to better understand Safety probably first and foremost but also appropriate indications for use in. It's done to a number of different mechanisms of the fda has an important responsibility for ongoing monitoring and and monitors databases from patient health records and insurance and other things that is de identified but It's a large database. So you can get information about you. Know emerging issues or concerns or query the database. If you need to Also fda works with companies and with patients and healthcare providers. Everyone is urged whether Provider or patient to report in a unusual conditions. That might be related to vaccination many reports. Turn out not to be things happen. Medically that might coincide with having gotten a vaccine but have nothing to do with the vaccination south but but things do get interested in patients that are concerned are their healthcare providers Report and companies also are doing ongoing monitoring As part of of studies. They've been asked to do or that. Are ongoing or because they hear from patients and healthcare providers in cdc also has a a vaccine reporting mechanism that they do in coordination with fda so those exist and they're always out there in place helping to make sure that vaccines are as effective and used as safely as possible in this situation because the vaccine frankly has been made you know more rapidly than normal in the context of evolving outbreak. And because we are giving it to you know many more people in this country around the world than you normally give a a vaccine and much more quickly The the importance of monitoring is really enhanced. And so you know really making sure that we don't lose people through the cracks is going to be more important than i think. It's in the interests of individuals and communities As well as as really understanding the science and appropriate use vaccines ad whether we need to be modifying our vaccines example new variants of this virus. You really are emerging and take hold that might impact the benefits of the vaccine right now. We don't believe that's the case. But we need to be monitoring that so so this notion of monitoring. Is you know at the individual patient level but it's also much more significantly at the population level to really understand trends in a and potentially emerging issues or concerns. And if you refuse it wouldn't be considered a vaccine adverse event but it would be a concern. I think in the context of the healthcare delivery and public health system..
"19 vaccine" Discussed on The World Next Week
"Feel like i'm just the messenger here from what i've heard i couldn't hear more tonight. But yes that is. The serology diverted essentially leave no stone unturned in terms of potential sites safely administer. The vaccine a lot of this is going to be just nitty-gritty details where two people park their cars. Whereas i mean. I can say this when when i've been thinking about our own vaccination clinics in the amazon world for a warehouse workers. Where do you have. Where's their space to actually monitor individuals for up to fifteen minutes. And how do you think about that holding Just that holding area And making sure we have enough is on it. There is an allergic reaction. Let's say mean. Those logistical details will need to be worked out. But yes community. Centers places of worship of all of these are under are under consideration. There really thinking big a glass. I i i feel like national guard has been deployed in seven states. Right now in forty three. It has not for some type of kobe response. In addition to i there's only so much the federal government can do. They really need state governments to play ball here. When it comes to the point national guard. And then i i do think the administration should leverage the military branches that they have available to them. The four branches of the military that can have tons of medical expertise that can do mobile clinics that can set up triage tents. I mean that is the expertise of our military medical branches. I stay that percent experience. I i just hope they start to leverage those capabilities as well but just just to jump in quickly. I mean. I think it's important to understand in all of you. Working the state and local level. I think do appreciate this that the federal government can provide critical support to provide a framework for action And they can provide some hands on activity but it's the coordinated approach with a sort of a mutual commitment amongst all partners to make progress. That is really going to provide success so at the state local level. You know better than the fence. About what kinds of resources you have what you can mobilize from mobile vans to fora. That might be suitable for setting up vaccination clinics. You also obviously needs some financial resources that have been you know slow to come and i hope that they'll be more for that as well. Because you're stretched so thin. But i think that it's really this sort of notion of looking at what what resources and opportunities you have. Also what special needs in terms of particular communities at risk and then how will align that with. What's happening at the federal level. And i hope that the incoming administration will be very very clear about what they're doing. And how and why is that will make it easier for all the moving parts to really align dr johnson. I wanna ask you to restate your seven priorities of somebody asked him will be sharing the link to the transcript and the the webinar after the fact that if you just state them again and then i'm going to go to Ask represented diane power power to her question. So over you dr johnson and then we'll go to the representative okay. The the the seven things that i mentioned were this and i will stir all try to read the slowly. You need a scientific background a basis you need to think in terms of the clinical the logistical as just mentioned The community dig in terms of human rights again. Churches play can play a role in that the behavioral communication facets on on undisturbed distribution of healthcare. So those are the seventy really need to look at. Thank you okay. Let's go to representative power good afternoon. Everyone thank you for taking my question. My name is diane. And i am a new hampshire state representative and my question has three parts. Dr hamburg stated the necessity of tracking people who received the vaccine in an effort to qualify the vaccine's efficacy duration of protection as well as any potential adverse reactions. Constituents of mine are concerned about privacy. So my questions are as follows. I'd like to understand what body is the clearinghouse for this information. Would it be the cdc to what types of patient data will be required to be collected and by whom would it be at the state level federal level in how will that information be dispersed and three I'd like to understand. Is the refusal to receive the vaccine with that be defined as a vaccine of and with this be recorded. thank you well. That sounds like a question that i should at least start with you know it is routine that vaccines are monitored in the real world in order to better understand Safety probably first and foremost but also appropriate indications for use in. It's done to a number of different mechanisms of the fda has an important responsibility for ongoing monitoring and and monitors databases from patient health records and insurance and other things that is de identified but It's a large database. So you can get information about you. Know emerging issues or concerns or query the database. If you need to Also fda works with companies and with patients and healthcare providers. Everyone is urged whether Provider or patient to report in a unusual conditions. That might be related to vaccination many reports. Turn out not to be things happen. Medically that might coincide with having gotten a vaccine but have nothing to do with the vaccination south but but things do get investigated in patients that are concerned are their healthcare providers Report and companies also are doing ongoing monitoring As part of of studies. They've been asked to do or that. Are ongoing or because they hear from patients and healthcare providers in cdc also has a a vaccine reporting mechanism that they do in coordination with fda so those exist and they're always out there in place helping to make sure that vaccines are as effective and used as safely as possible in this situation because the vaccine frankly has been made you know more rapidly than normal in the context of evolving outbreak. And because we are giving it to you know many more people in this country around the world than you normally give a a vaccine and much more quickly The the importance of monitoring is really enhanced. And so you know really making sure that we don't lose people through the cracks is going to be more important than i think. It's in the interests of individuals and communities As well as as really understanding the science and appropriate use vaccines ad whether.
"19 vaccine" Discussed on CFR On the Record
"The four branches of the military that can have tons of medical expertise that can do mobile clinics that can set up triage tents that is the expertise of our military medical branches. I stay that percent experience. I i just hope they start to leverage those capabilities as well but just just to jump in quickly. I mean. I think it's important to understand in all of you. Working the state and local level. I think do appreciate this that the federal government can provide critical support to provide a framework for action And they can provide some hands on activity but it's the coordinated approach with a sort of a mutual commitment amongst all partners to make progress. That is really going to provide success so at the state local level. You know better than the fence. About what kinds of resources you have what you can mobilize from mobile vans to fora. That might be suitable for setting up vaccination clinics. You also obviously need some resources that have been you know slow to come and i hope that they'll be more for that as well. 'cause you're stretched so thin but i think that it's really this sort of notion of looking at what what resources and opportunities you have. Also what special needs in terms of particular communities at risk and then how will align that with. What's happening at the federal level. And i hope that the incoming administration will be very very clear about what they're doing. And how and why is that will make it easier for all the moving parts to really align dr johnson. I wanna ask you to restate your seven priorities of somebody asked him will be sharing the link to the transcript and the the webinar after the fact. But if you just state them again and then i'm going to go to Ask represented diane power power to ask her questions. So over you dr johnson. And then we'll go to the representative. Okay the the the seven things that i mentioned were this and i will stir.
"19 vaccine" Discussed on The World Next Week
"The national institute of occupational safety and health advisory board. So welcome dr gupta. Hamburg and johnson. Thank you very much for being with us. We are now ten months into the coronavirus pandemic in the united states and around the world and pataudi rates here in the us or higher than they have ever been on. This is obviously an immensely difficult time for our country and we look forward to hearing your thoughts on the vaccines every seed. Emergency use authorization from the fda. What's on the horizon on the challenges we face on a distributing the vaccine as we know we gone off to a slow start here in the us So dr hamburg. I'm turn i you to talk a little bit of the process that these vaccines have gone through to get the fda approval which ones what else is on the horizon. I know there are several more in on the verge of breaking through so over to you. Well thank you very much privilege to be part of this distinguished panel and always enjoy working with cfr and you know really so glad to engage with state and local officials and people working on the front lines. Because that's you know where we really make the the real and enduring differences because even though tremendous things have happened developing the vaccine making sure it actually gets distributed to those who need it gets used properly is what will make the difference in our ability to controls this devastating pandemic so. Let me talk a little bit about where we are with vaccines and and what to expect will try to be brief so we can have lots of time for qna but it has been a remarkable achievement. Really the scientific research and development community has come together across disciplines across sectors and across boarders to really move science forward in remarkable unprecedented ways in less than a year from the time that the virus was actually identified in its genome posted on the web by chinese scientists. We actually had developed A range of vaccines that Some of which are are now authorized for use in this country and elsewhere as many probably no vaccine development normally takes a long time often a decade or more and it's done in a very staged way it was sort of pauses in between to sort of assess it can be a high risk undertaking a lot of vaccines fail and it can be a costly undertaking but in order to respond to the demands of this unfolding pandemic The regulatory authorities like the fda in the research community both industry and academia really worked quite closely together to design studies that could accelerate the process in compressed normal stages of vaccine development without compromising safety and efficacy. And so we have seen A number of vaccines in development in this country and beyond right now. They're over a hundred vaccine candidates that are in the pipeline and animal studies There are about twenty that are in the final stages of of large scale testing here in the us we have to vaccines that are authorized for use in. We anticipate a third probably being authorized when the full data analysis done Later this month early february. That's the johnson and johnson vaccine which actually is a windows vaccine the others are pfizer and moderna ball been hearing about this and there to dose vaccines with more complex supply chains while require You know significant freezer storage and transport especially pfizer and And they are using completely novel technology. what's called messenger are m. are there in the course of development in this country and other countries there there been many different categories of vaccines that are being developed. And that's been a good thing first of all we didn't know which types of vaccines might work most effectively and proved safest But it's also good to diversify your portfolio because there may be vaccine types that were better in certain subpopulations or others. So there's a huge enterprise going forward and huge progress That's been made as i mentioned Here in the us to have been authorized for use. This is not approval. This is an emergency use authorization which is a specific category That's been developed in in fairly recent times in response to the recognition of of public health crises. Either naturally occurring or deliberately caused where you may really need to move products out with. You don't have as much information about them as you might like. But you can assess the relative risks and benefits. And that's what's happened here but there will be continuing study of these vaccines even the ones that are going out for use as we speak with more data collected as part of the final approval process. And it's important to also recognize that as part of really these vaccines real in terms of getting them to the people that you are working with. Every day in states and localities the distribution of these vaccines is crucial to get them where they need to go to make sure that people get their second dose of the vaccine in the right timeframe and also from the perspective of regulatory authority like the fda the ability to track who's gotten vaccine and monitor their real world experience with the vaccine in terms of deepening. Our understanding of of efficacy. How well protected our people. We know that the vaccines that are authorized for use now reduced severe symptoms in serious disease. But we don't know for sure how completely they protect against infection a symptomatic infection and the ability to spread. We need to learn more about that. We also need to learn about the duration of protection from these vaccines in well. We need annual boosts or will they last longer.
"19 vaccine" Discussed on #LifeAtGeisinger
"From a allergy standpoint but because of that the p. has a said that okay. Well if you do have a history of severe allergies to like foods are animals insect venoms right medications environmental antigens then after you get the vaccine we want to recommend that you stick around and be observed for fifteen minutes after you get the shot and if you're somebody who's had antifa laxest other vaccines are injectables. Which is of course is severe allergic reaction as you can have then they want you to stick around for at least thirty minutes after you get the injection and so that's something that you should think about. Maybe prepared for if you're coming to get the vaccine if you're not sure where you fall into that category than feel free to reach out to of course Either your physician or primary care provider. Are those of us in infectious. Diseases are Other specialties that may be able to kind of help Give you some guidance when you look at the face retrial. We had a lot of participants in there and we do not notice any serious Allergic reactions and now we're opening up this vaccine to essentially millions of people Some individuals we know they have this allergic they offices. You wonder if that's just the the primary reason for that but again you know it's worried that we're doing our due diligence and you know asking these questions as we're obtaining more information in terms of you know what doesn't underlying allergy mean so we will be continuing to monitor that closely. Were extremely excited about the development of this vaccine and even more so excited to talk about such great numbers on ninety five percent effective is just astounding and although they're extremely impressive members That should not replace the strategies that we know Help prevent the spread of covid. Which again are masking and social distancing and hand hygiene. And if we do feel With cova like symptoms We certainly still have to follow the same policies that we did before we received the vaccination a lot of questions about how long does immunity last after receiving the vaccination and You know it's a it's a great question You know we're still collecting the data for that. I think obviously a lot of us listening to this. Call a heater. You know numbers in the months if not you know potentially a year but again. We're we're still collecting all of that information so You know really important Not to look this vaccination as a replacement of those measures that are currently applying to help prevent acquisition but the spread of covid right You know the data does look very promising as you say alison and we've seen some published numbers Which suggests that a effective antibody certainly can be in place for a good three months. And we know that it's probably going to be much longer than that But the the element that we need to show that is time And we haven't had that just yet right So expect more to come on that front. But in the meantime as you point out We are still going to have to be very conscious about guidelines for print prevention of infection. Both here in the healthcare system and statewide Right because we have mandates from the governor's office As well as our own internal policies for prevention of infection that we're all still going to have to follow for now which include of course the masking the hand hygiene the social distancing those are elements which we know at the end of the day. Really do a good job of preventing the spread of infection. I think we really went through a lot of great information stand and went through a lot of what we do. Understand at the at the current moment about this vaccine and About the vaccines that are up and coming going through the same approval process But we're still continuing to collect information recommendations may all as we get Excuse me information about these. Vaccinations in certain populations so You know including the the pfizer trial were still continuing to look at these participants. Were going to continue to follow them up. And we're gonna keep everyone posted as we get that information coming in..
"19 vaccine" Discussed on StarTalk Radio
"Control everything it doesn't matter what? The day are they know the truth they know that Bill Gates started all this. They know that the the virus is transmitted through the five G. Network. They know that influenza vaccine actually has SARS. Koby two hundred they know all those things and there's no talking them out of it. So I don't think anything will convince them of anything other than vaccines are always bad How, about just saying that, have any of your friends recently called into work sick with smallpox. How about how about that? That's a pretty convincing who was it that said you can't use reason to argue someone out of a position they didn't get into by using reason took point. That's. One of the great shows. So Dr Often, I didn't I didn't and thought about it these two separate camps, and so it seems to me if you could convince people who are skeptics that will take us quite a long way and the rest are just you're not going to get him no matter what. Yeah I think reasoning logic works for people who reasonable logical of you just have to find a way to, and you do this better than anybody to convert difficult scientific issues and try and make it understandable and presented an compassionate and passionate and compelling way, and I think people aren't invincible as long as. Data can convince them but never mind reminder for quote of Ashley Stevenson when he was running for. President you know he's a intellectual right and he and. The cocoa something like she says, but I I have the vote of every. thinking person in the country and his his teams but sir, you need a majority. But but but a cynic on vaccine is doing the same thing in a way as people who won't wear mass they're putting others at risk by refusing to protect themselves right so there is again going back to this sort of social responsibility and ethics question that you can't seem to get around in my right exactly. Right. You're not making your decision for yourself only if you want to die SARS Kobe to that's your position, but the point is reporting down other people with you. Okay This is also from Patriot Vander Linden. Do we already have an idea of what people will be what people will be vaccinated? I will it be the most vulnerable or will it be specific groups that have the potential to be super spreaders? Is there any strategy for this and who will be responsible for executing the strategy a brilliant? Question Yeah, right through their two groups of make this decision. One is the so-called Advisory Committee for mutilation practice, which advised the Centers for disease, control and prevention or CDC, and the other National Academy of Medicine both of them are in I've been putting out actually who will be that I hear.
"19 vaccine" Discussed on The Signal
"It's been talking shocking. Waking is judges against nineteen, so in the face of what is starting to look suspiciously like. Way How is that vaccine coming along? I'm David smiling and I'm Angela Wocka and today on the signal, some good news from two places on the rights for a vaccine. Could it really be less than a year away and if the virus mutates in the meantime, will the vaccine.
"19 vaccine" Discussed on RNZ: The Detail
"We hear law particularly out of the US about up domestically about medicines that were created for different illnesses having applications against have nineteen the most Talked probably hydroxy chloroquine or via. How does that were here? Each amount of work looking at things that we have available to us in the Tokyo. We've done a lot of drought coming on mind-boggling amount of drugs. It's possible that some of them my head are should against against the far. He's some that they're looking encouraging and they've saw it very easy. If you've got something existing to recruit us. It doesn't have to go. You know you already licensed that you've already Wouldn't it be great if we had something else to show As opposed to developing brain. You things from scratch does covert nineteen. Does it have characteristics which make it especially difficult to develop a vaccine four or is the period of time that this is taking because it has only been. What four and a half months? I is this pretty par for the course when it comes to developing a vaccine for a new illness now already. This is crazy five. It's unprecedented before the the foster a vaccine was ever developed. You know from scratch with the month saying that made the mumps vaccine was licensed in nineteen sixty even after about four years of development and recently they abolish vaccines Had been developed tycoon them many years to develop them that they actually got them through. Tcm theory very quickly which showed up they sent Cain. Actually they done but no is this is untreated and says know. We're in a new. We're in a new New Space now with with what we can actually achieve right now. It is a great vaccine vaccine for Corona Virus and today scientists at the row are a step closer to a breakthrough research unit based in Flanders Scientists announced the discovery of unique antibody. That's capable of neutral. Is The virus that causes cove in nineteen the source. Allama every now even then we kind of you know we. We read the news some of skew eleven in Tel Aviv. Or whatever. His his made a vaccine breakthrough. Everyone gets really excited. It feels to me like a good way to think about this. Maybe as a sort of a vital piece of global infrastructure global health infrastructure and if you think about global physical infrastructure things like sewage canal. They do take years to develop and you just have to accept it because he can't bloody canal in six months. No I think you've got some sort of star right. Putting blast once once seen is develops Helen. Who Actually owns a good Christian In this case because when Scott sign any players I think it's going to be very at your You know big Pharma will still own their own property. Maybe they gotta might the profit for a while but that's still on a net and anybody else who has ownership also but What's happening is that people are making via technologies available to other. That's what was saying and also isn't that thing of being funded by for example. Sippy who I mention Julia They doing four for the world particularly for low income countries so those things at least likely to be caught up ten intellectual property. I think you're gonNA say the whole gamut but by and large what you're saying is my pimple publishing very quickly and sheer and daily learning and we'll say collaborating with others so that we aren't you talked about issues of production mascow production before if company or country convenes a vaccine and it was feet of wood. We need to produce a dose of the vaccine for every person in the world to eradicate the disease naughty naughty but mice turn them on their bottom line. You're going to need billions of devices of vaccine. Is it like making Marinara soup kitchen. You just brew it up and a great big TUB right and but I of new you know they. The color silicate a vaccine production facility will cost you in. The order of one billion dollars is not for the fight So so you you caught me too. Tight facilitated the pumping out Viral vector that things and suddenly stopped pumping out An excavating they had that that would have to be adapted so many facilities in the world of course India for example one of the biggest producers of vaccines for the world. There's a mini facilities. But no not so I understand Bill Gates is closing. Sieben billion to build Stephen facilitate belt them now. Knowing that some of them might not be used the money so that you paid to lose the money you can You can stop these things. But that's the challenge that we're GONNA have to come. Which is why I think you know if it's a place has a capacity to manufacture at the standard required which is during high then. You probably want them going that year because The the the the fate of the measure is that you can't. It's not like him. War production we can just sort of. Tell Rose Royce start making cars and to stop making rifles existing. Vaccines do still have to be made because the astor. We're GONNA be flu season. So it's not that you can simply converse facility to making a covert vaccine because the leaves imbalances with other victims. You have to sort of Ed. The covert production to what? We're really producing. Which is a fast. And you don't normally run else to vaccinate the entire world's population you normally but the focused on you know I tell you something a big. It's a big challenge Dear Helen just finally I mean we of course being into the realm of speculation. Kia but once you be skis to win. We might be able to develop. Are we talking months? Who We to you the company the only at is probably the only way we can bring truly get after. That's out of the PETCO. I thought people time line. The timeline is short And I think the one we need to be drinkable. Prepare for and that is a teacher for the foods capital cab off the rank going well could be to the end of the field and so you have to be ready for that Because use a lot to do you can't just deploy them into the population getting a whole other things really. So that the the very thin accord you've got to You've got to. You've got a Mike enough people but it's not going to be available to everybody lies away and so that's going to extend that might be looking earlier in the eighteen months and I think one of the things we need to think about as well if you making it yourself you'll probably going ahead access to something Ilia Nvr. We'd you know we're news. That's already started making stuff so You understand that and I think that was probably do the same well so so we this really is the. This is a long haul kind of thing you know. The idea of being a Eureka moment and corvettes being out of system and time for the out of society in time for the ski season in Queenstown. That is just you. Just get recalibrate those expectations right now. I mean if we had colleague within you go skiing in Queenstown right. I believe you're going to be encouraged to do so. I'm just just saying that. The best thing that things about offers Looks to be a WANNA and comes up really well in terms of safety and a lot of places might give themselves up about pumping it out. I you know I. It depends if there will we need to have to stop building the facility. Scratch VINCIT for today on a meal with all of the detail is brought to you by newsroom dot card audience. He'd and made possible by our inside. And you can get US downloaded free to your mobile phone every weekday from any podcast platform. And if you using April please give us a raging. Other people can find us to. This episode was engineered by Blair stake pole and produced Aleksey Russell. And thanks to Helen. Producers Harris Cocky Danell.
"19 vaccine" Discussed on Vox's The Weeds
"Need for an immediate solution. He was in his current position during the AIDS crisis and there is a New Yorker profile of him for a couple from a couple of weeks ago. That gets into a certain amount of detail you know. The initially antagonistic relationship that activists at the time had with the entire Reagan administration generally for entirely understandable reasons from your name that was killing people. Apparently because it was killing gay people but ultimately he came to an understanding with some of the activists. Who were you know? Really putting pressure on him specifically and began to kind of develop relationships with him. Larry Kramer who is a very famous and very cantankerous AIDS activist speaks highly respectfully of him in Larry Kramer's speech highly respectfully of approximately no one. And so it's thinking about not just the political dynamics of like oh he listened to them he did work to make sure that testing was representative of the affected populations that they wanted to identify and that kind of thing but also the science of it he was. He was doing inter alia was a allowing people to engage in multiple experimental treatments at once which was a very literary concern and be speeding up the phase two by allowing broader adoption after the safety had been guaranteed to test efficacy. Because there isn't a strong argument for not letting people access a treatment that has been preliminarily demonstrated to be safe. If what you're trying to test is that it's affected effective. The problem with that of course is that there's a big difference between testing treatments and testing prevention measures people who had HIV in the nineteen eighties already had HIV that was defined population of people. And so there isn't in the same way a particular population of people who would be the first to sign up to test this treatment. That might not work because they would particularly benefit from right like if you if you think about the ways in which people are particularly vulnerable to corona virus would potentially make them more exposed to adverse effects of other drugs if they ended up getting the corona virus that wouldn't be a good outcome of the study even though testing efficacy was supposed to be the point so that there is that concern there. It's not exactly as if Anthony Fauci is the exemplar of a dude who will never be you know who would never speed up the rules if there were a greater public health benefit. I think the question is which phase you're talking about phase phase. One is obviously a problem to speed up. This is what we saw with the chloroquine issue. Where one of the major studies got suspended because of the development of Heart Arrhythmias? You have to test that. There aren't significant adverse impacts of treatment first phase. Two is easy to speed up. If you do have a defined population of people for whom you would be able to know if it's safe but in a situation where the phase two and phase three potential populations are like the exact same people speeding up phase three and getting to that kind of long term data collection point with healthy people who a daily would be able to get the health treatment. They needed if they were to get infected is a good idea. Here's the other problem though. I'm not sure that we actually have a very good idea of who the people who are least vulnerable to the corona virus are exactly lists of into new indicators symptoms. We keep hearing new problems. That people are coming into hospitals with particularly people in their thirties and forties. Not to say that those are the people whose mortality rates are highest. But it is to say that epidemiologically. I don't think there's a group of people that we can say for. Sure is in good enough shape if they can track the corona virus that they should be the group we should pick to test general efficacy of a vaccine. I think that that's a really important point. Because how we've been talking about the people most at risk to corona virus. I think makes it seem like it's a much more disparate group that it actually is because there's been like we need to protect the elderly with pre existing conditions. And what that actually means is people over fifty who may or may not have high blood pressure and a host of other coexisting factors. I looked it up yesterday. And that's a ballot. Like fifty to seventy million people. I used to work in the HIV space and in terms of the research. We were doing on that. Which at the time. When I was working on the space focused on reducing mother-to-child transmission of HIV. You had a very distinct and disparate population. You even were able to have especially with people living with HIV. You could even look at people based on whether T. Cell Count was at the time and for testing drugs like true vodka or even the wider example of prophylaxis against HIV essentially to prevent the transmission. You have again a distinct population now that population men who have sex with men or specific groups that can get a little wiggly because of how some people self identify but again you have a disparate population with corona virus. You have kind of like well. People over fifty with these existing characteristics but also not necessarily people over fifty because again as Dr points out. People in their thirties and forties are getting very very sick especially those with pre pre existing conditions like asthma which I have and so I think that that is one of the challenges here is how the distinct nature of some of these groups makes it the non-district nature rather makes it particularly challenging to think about this research perspective. Okay let let. Let's take a break and I wanNA come back and push more more enthusiasm if you WANNA stay up to date on the Kern conversation climate change. You absolutely need to be listening to the climate one podcast..
"19 vaccine" Discussed on Sidenote
"Who's from Hong Kong about sort of the cultural differences in terms of because Hong Kong was really hit hard by SARS and ever since then as population. It was like they are willing to do what needs to happen. And the second that this virus sorted out breaking people were willing to socially isolate and listen to that advice and it's been kind of ingrained in their culture to like us. Hannitized often wear masks on a regular basis. So what is the cultural difference of our societies? Having never doubt with this maybe this will change after. But we don't we. Don't listen to this advice. We're going to see that okay. I'm not going to try and go into much of a tangent here what it leads to another conversation. That's been disturbing to me that I've seen start to grow out of this. Which is why don't we just let people? Let's just let them die like it's not the news out of that. The new talking points right now is. Let's not destroy the economy. Donald Trump's line right now is the cure. Can't be worse than the disease. So they're thinking that because the cure is to destroy the economy. We'd rather kill everyone who would die. Because it's just old people and so I think that's like really messed up and I actually saw something that Diana visits girl just re shared in tweeted that showed the hospitalization rates have different age groups and for people. I don't know the exact age range I think. It was between twenty and thirty five. Something in that bubble was still twenty percent of people that age get hospital. That's what's not just because you're not dying and if the hospital systems overwhelm what happens when you weigh in Bohol and you break your leg then. The hospital is still that you would be still like. Oh my God that's insane so just really sad thing and it's really frustrating because a lot of places obviously somewhere like New York I think is now taking it so seriously but why does it have to get to that point and our other cities including Canada. Toronto looking and going. We don't want to get there. We really need to self isolate. The honest truth is in a perfect world. If we could wave our hands and all isolate for weeks we could deal with this but obviously there's so many issues associated with by. You need to get food. You need to whether it's groceries and were having. There's nurses and doctors have to keep working. But without the the coherence of society to listen to these roles. It's is it enough. If only fifty percent of people isolate. Is it really doing anything at all? But half destroying the economy and the not even solving the problem. Oh God oh God see. This is the things that'll make me not able to sleep. I think about but yeah I do. Think Hong Kong is a great example. We did the studies last week. Looking at what their impact of self-isolation. So they all knew they all have self isolated before will in two thousand three so they were alive during that time. They've all self isolated. They've gone through what we're all going through right now so it makes sense. If this ever were to happen again we would start self isolating easily but we yeah. I think we as the death toll gates higher and it's interesting to read but I'm trying to say that if this were to happen again say in ten years after where if it stop today right now yeah we would still no hope people would way okay then we disagree because I still think the idea of self isolation has now become something we are all living with. We didn't know about before. Sure if there was a pandemic that broke out in the same way in five years we would all a the governments would tell it more easily. We'd go. Hey guys get stay at home. During athletes re would we have already learned a lot? People's lives have changed. I don't think we need to be so just because some people are haven't clicked to the same extent that you and I both have doesn't mean that we haven't already all learned something from this. Oh I agree with that. I just mean I think a lot of people even if even some people who are self isolating aren't taking it so seriously and haven't seen it directly impact them yet that if if if this were to end today and everything be solved and we have the death toll we have. I think that it won't wouldn't trigger our society at large enough to immediately understand. It's worth shutting down the economy. I think so. Many people are worried about money right now but if they can see where this goes and it's true. Okay yes mostly people who are dying are above seventy but that doesn't mean there aren't scenarios where young people have severe complications. There are lots of young people who have already pre existing conditions. And they're not the only ones who are ending up hospitalized and I don't want to scare people like we. If you're young you most likely will be healthy even if you get it. So I don't want people to feel like I'm trying to fear monger or anything like that and you may get it and you may not have any symptoms but I think we need to have a little more compassion for everyone else who you don't know who the people are. We know there's a lot of all people are going to be impacted but you don't know which one of your friends or yourself or your family members might or might seem like somebody who you know is healthy is great is young and my have a complication and is it worth that risk. Because the economy's losing money like you're willing to risk your friends lies in your own life. I don't know obviously I understand. There's a conversation of how we managed the economy how we get through this in a way. That doesn't stop food from getting to our grocery stores so we can actually eat and things like that but it's just feel so uncertain to me right now and yeah. I mean well. I'm just GONNA do my usual thing before we wrap up. Which is just my socialist. Instincts are going to pop off. Which is that Amazon? Didn't pay federal tax last year. Sixty of the biggest corporations in America didn't pay federal tax last year. This is why you need to tax corporations when our economies are thriving and booming 'cause they're making billions of dollars of profits and that needs to go back into the government and the government needs to then use those that money and times like now in order to give the money out to the people who need it the workers on whose backs you are making these corporations in order to create a society that is more just and I think and I hope and pray. This atheist is prion that we will learn from this in order to do this better in the future in order to look after citizens right now I mean it is kind of interesting. Who are the people who can stay home? Is Your job no. I don't go down but I'm like the people who are still having to work are. The people who are being paid are so fricking important because society the people who need for society to keep going at a time like this are interestingly the people who are not paid that much the know who's sitting at home a lot of these rich unique. I mean worst sitting on exactly. We are a perfect. I think you need to make it a little more personal to not talk about us. We live in Canada where we are taxed as much higher than you are in America and I will tell you this as people who make way more money than I ever expected to as someone who just planned to be a high school teacher it is so important that we are taxed because you cannot expect these rich people to just give money for example. I give to charity. I do my personal part. But for example when I sponsored a Syrian newcomer to come to Canada. It was the work. That was the big issue. I was going with him trying to figure out all the driver's license and healthcare it's like Oh my God. The issue was the work and the time and that is also stays a really philanthropic rich person as really good tensions. But they don't have time they're rich and they have running their companies. They don't have time to think about charity so they need to be taxed and that money needs to be figured out how to be funneled into housing into other places. Because that's what they do. They take the money from them and then government figures out what to do with it and you can complain all day. About what the government is wasting all this money but I'm sorry repay a lot of tax for example on our home and we got their receipt. We pay a lot of taxes. We paid a lot of money for our house and we see where that money goes to and it goes to affordable housing in the area. It goes to parks goes to all of these things that everyone else can enjoy. In order to create more Justice Society need to tax corporations and need to tax rich people. And if you are against that you need to think about why the heck you are meant a personal example of being self deprecating like Shitty people with jobs. We've got to work from home okay. Let's talk about this. I was we get to work from home but I'm saying I'm happy that I get taxed too long. Yes ultimately wanted to make the point of. We should be so appreciative. And not forget this. When it's over of nurses and doctors and scientists Anger Rocha clerk workers and people who are having to work now to keep society functioning at all and putting their lives at risk. Who not only can they not work from home? We actually are demanding that they continue to work otherwise society will fall apart. And in that case I'm trying to be like young. We are not that rule. No of course we have our role to play and hopefully science communication all our friends and people online. Who are doing this. We appreciate them so much for doing it. But there's another level of we're realizing who the people we need in our society. Our I hope this whole pandemic is over. We don't forget that and that we users build our societies around people and lift those jobs because we've certainly turn on a dime to be like. We need them now. And it's just sad to think that maybe they'll be forgotten in that sense in that there is not gonNA. Nfs. We cannot let that happen teachers. I also WANNA put in there as well. 'cause a lot of parents right now are being like how that someone who like my family. It's like my sister's healthcare professional. I want to be a teacher like these are the jobs that matter and I really really think that that is so important. People realize that you know what I mean when you're at and you're complaining about your kids teacher or you're complaining about don't any time or the nurse it's like think twice. Greg. I don't know if I've ever heard you get so heated on this park. I actually think the most I've ever heard you get heated. Really felt really passionate and upset. But that's a good thing I'm GONNA go. No you were fine. We're.
"19 vaccine" Discussed on Sidenote
"On trip like a subtle really nice so nice so back Vaccines Okay. So essentially to make a vaccine not TACO CORONA virus. Right now let's talk about a vaccine that you will all have hopefully received at a young age. Maybe it's polio vaccine. Maybe it's smallpox vaccine. How do those is that you start by actually sequencing the virus then you actually have to generate the virus and then you have to test it in animals and as we talked earlier. That's usually mice working your way up to a monkey similar to humans. And that's when you then start human trials which is what they've already done In Seattle with Madonna and those are small populations of people where you give them the vaccine and again you wait you wait to see and make sure that it's safe. Make sure that things aren't getting worse. Then you move onto a second phase where you then tested on thousands of people again in a similar population where the disease is like the occurring and you wait and you give it to some people. Don't give it to others and then even pretend to give it to them but you don't actually give it to them plus zero blind and then at that point you then move onto a third phase where you do. It's even more people before eventually going for a license before you actually then have to get all these approvals before anyone ever received the vaccine and this takes years years and years before a vaccine will ever be given to you unless it's something like flu vaccine or the actual ways that they make it. They've done it so often and over and over that is just about them every year tweaking a little bit so we know how safe it is. We know how rigorously tested it is and this. Every year they add end. A new type of flu viruses that they predict are going to be going around the population that year. So this is to say that these things take time and even this modern vaccine which they have already started human trials the earliest that they ever think that they are giving it to. The general population would be one year so do not expect that sort of in the perfect scenario right into that does nothing goes wrong. That's that's you know there's also a chance that does nothing like they'd be doesn't make things worse but it might just not even do anything. So yeah that's that's in. And they have to know all that before they can scale up because then the last part is how do you give it to the world's population right so there's this whole endeavor of? I make sure it works if you can't start spending so much money on developing a vaccine if we don't understand the long term implications and it's kind of something we didn't talk about in our video out to this podcast is about because it's very contentious this. These axioms are being studied around the world China in America in Canada people doing it in Dalhousie at U. OF T. And it's because if one of these people figure out the vaccine that works and let's say it's a year and a half from now and again that is the time line. Early estimates are about a year conservative. Ones are like two years if it's a year from now and they figured out they're going to build up and manufacture this to inoculate their own citizens. I say China got the vaccine I. They're obviously going to be giving it to their own citizens for us so that is why it is really important that a lot of people do this but why we also have to remember that getting a vaccine everyone in the world is going to want it and that is going to be a time for really important ideas of coming together of patients of you know worldwide efforts to make sure that it doesn't create a negative dangerous place where people are economically are paying for it like the richest countries got it. I like how is this all going to work? That is something that we have to think about right now because that's going to be happening in the future but if Canada comes up with their vaccine I that's the most likely to be used. Obviously they're gonNA inoculate their country. I so that's just something that's worth thinking about. It'll be a long ways away so we maybe I'm just so interested to see where things go at this point. Obviously we're going to hopefully keep working on this axiom because there's problems big enough and could happen again in the future whether or not there's more outbreaks if it contain it now. It's just so uncertain. What do you think is going to happen in terms of like? Where do we go right now knowing that okay? This vaccine isn't gonNA come soon. That's sort of what prompted us to WanNa make not only this podcast episode. We made in our channel because we had heard anecdotally from friends and family being. Oh you know this will be in isolation and then if you weeks hopefully they'll have a vaccine so this idea that we're gonNA have it soon and in a couple of weeks we can start giving it to be bull. We just were like we know that's not true. Let's do the research to see what experts are saying knowing that. Where does that leave us? I mean it leaves us in what we all need to be doing right now. Which is physically distancing ourselves from people and living a life of social isolation in order to flatten the curve to ensure that medical professionals in hospitals which are already underfunded and do not have the ability to look after the human population. If everyone were to get around the world that would be huge issue. That's why what we're doing right now is mitigating. What's happening and buying time? But it is worth having these conversations because a vaccine is not going to be what is going to fix US short term and we know that for a fact you cannot ever start thinking that you're going to get a vaccine. There's no point in starting to think that you're going to get a vaccine within a year because that's just going to be astounding if that happens so it's better to be on the safe side mentally and I think where we're at now and for a new video that we want to do. And hopefully maybe even next week's podcast will be about antiviral medication because I think that for me is a place that could help a lot with like symptoms and treatment and I think even just beyond viral 's therapeutics are being created to help people manage their symptoms to help people recover faster to help kill. Excuse me kill the virus if possible. There's so many other things so there is still like a level of hope that people should have and scientists are putting so much time and effort into figuring this out and governments. I think are throwing money at it right now. Because they're not scenes aren't going to be what we got within a year and they are going to be a a lot of things we have to figure out in the next year before we ever can expect to start inoculating the world population from SAR. Cop Too. But I do think thing you shouldn't do is listen to the president of the United States Pretty much ever. Because it's so dangerous what he did just going off and talking about these like Oh my God like talking about medication and telling people to take this. Medication is so dangerous doing it. I was about to pop off. Just think so. There are people who I saw defending miss. Because they're going well. Look there's some evidence for it and I think what people need to realize. Is that much like the vaccines get tested for extremely long periods of time. So do medicines so do drugs and so even if there is a little bit of evidence that actually also say that the evidence is murky and limited at best because it was all anecdotal coming out of China that they were just throwing? It wasn't never in a controlled very severe situation and it wasn't studied so that's the problem. The doctors were trying to give anything to help us get better anecdotally. Some of them thought. I think this may have helped. So the risk is that we're putting all this belief behind that when it actually hasn't been studied proven and we don't quite know the risks. Someone died recently because they were also taking some fish supplement or something like that. I didn't I didn't quite understand but They took the president of the United States advice and took that drug and now they are dead and so there are so many risks. Yeah it's like the first death from that drug has just happened and then everyone who is you know. Wanting to support the president is like yeah but they were taking all these other meds. That like conflicted with this drug. And it's like that's why this shouldn't be prescribed from the president. You need to go to your doctors so they can evaluate your medical history and they can understand if this drug is appropriate for you. Because lots of drugs have negative impacts and interact with other drugs other sorry interact with other drugs in negative ways that could severely damage yourself. It's honestly the most dangerous I mean. I'm a well on most things. One of those things that's frustrating because yes maybe at some point we will realize okay. This is one of the better treatments we can use. Maybe not though and so it's just coming from a tweet from the president and now also from his mouth in press. Conferences is just irresponsible honestly. Because there's not enough behind it and I get that some people are like but we want to act fast. But you may cause more problems than YOU'RE GONNA SOLVE. You will cost and under like starting to research antiviral medication like the way. These medications work is they. They limit your your cells ability to create energy or to read Aren a in order to stop. The virus does come at a cost to your own body. All of these drugs are used in serious situations when you have a serious virus at the cost of other parts of your physiology. So you can't just ever if you understand the physiology of how drugs work. It's not just as magic thing that goes. Oh Hey there's the virus boop boop boop should the virus and not affect any other part of your body that's not how toxicology how physiology how these things work so and Donald Trump can't read so obviously he's not coming at this from a place of understanding so it is extremely dangerous? I'd like we've gone here because I think I do think. Antiviral medication and medication is more of a place where? I'm thinking for a hope that it will be shorter term than a year to help with all of this. In the meantime we do know what does work and what you need to do is listen to scientists and medical professionals and what they are saying is stay home if you stay in your fricken house. It's not African heart or apartment or wherever you have flex you have the Internet. Just porn hub babe. Relax one other thing I was going to share. Potentially as my what he's doing this week I had just listened to another podcast about Hong Kong. And how they have so few cases given that they're so like right beside China. It was interesting to see that they had such low numbers and listening to this person talk..
"19 vaccine" Discussed on Sidenote
"Okay voice. I love vocal harmony. Not just like I enjoy doing it but I really appreciate artists who loved to layer their vocals. And just find some interesting ways. If you've never heard of Jacob Collie one of my favorite artists such job some of his only voices and it's amazing whereas I'm more Amazon Guard I actually like I'm on the Bjork style. Where like armies are actually just like wrong like have because I don't know it just sort of goes against the grain. Okay we'RE GONNA Today. We were actually talking about vaccines so we typically split this up into two studies. But I think today we're GonNa Kinda Talk. Broadly in about a handful studies the companies that are working on. Vaccines are video. Covers some of this and we thought it'd be interesting to go over even how vaccines work in the first place. Because I noticed on our video there were a lot of really positive comments that were just saying things like this has been so helpful. I don't know why I never really quite grasp what was happening. But it's made me feel a lot more confident and comfortable. Yeah getting vaccines and feeling like it. Just shows the power of learning so. I think that we are all starting to try. And figure out how this pandemic is going to shift the world and one positive thing. I think it's going to happen. Is it's going to absolutely abolish the vaccine hesitancy in ANTIBAC- Movement. Because here we are at a time where everyone is just desperate for vaccine. Imagine existing within those communities. Right now you would be. You should always have been ashamed but you would be ashamed and I think one thing. Oh yeah go ahead one thing. I think that this video didn't the comments that I really like. Resonated with is that we've actually made videos about anthrax movement really pointed and trying to explain why there's so much policy and why it's so dangerous but I actually think this video did a lot more for educating people and actually shifting the kneel on that then we realized because a lot of people's responses. I never got the flu vaccine but now watching your video realizing how much like rigorous research goes into these axes. How lucky we are to be alive. Amazing your body's immune so yes like learn exactly so I was. I really do think that what we're talking about today. And where the cove in nineteen vaccine ends up is going to change the world and I think we will not have to deal with that completely idiotic. Stance that comes from a lot of people inside definitely still saw some of that. So that would be my caveat to that statement. I saw some amazing responses from people on our video card. There are still comments that think that vaccines are a form of mind control. They think that this yeah. This is this is into conspiracy people being like. Oh this has been. They planted this virus so they could force us all to do vaccines either so they could make money or so that they control our brains bells like sometimes. I understand in America. It's different 'cause you presumably have to pay for vaccines that you get the flu shot. I assume you have to pay for it in Canada. You just go. So it's the government that's basically the government has to pay for that so it's like if the if this was on purpose the government's losing money but we can't go down that is always trying to be like comments by and then but why don't we talk a little bit first about how overview vaccines work vaccines can be either viruses or bacteria pathogens. We're kind of focusing on viruses because of the corona virus But you have the two main versions being live. And then you have like dead. One Live attenuated vaccine. Even the third kind I was GONNA say with sub unit vaccines and this is just taking a piece. Maybe like one spike from the virus or something that your body recognizes foreign gathers the immune system around and then starts replicating all these different types of immune cells some of which are memory cells. So even when it's been dealt with and some parts remain system back down you have memory cells that know how to respond as fast as possible. No the best way to destroy this particle or this virus and I just didn't that so cool to think that your body builds memory cells to deal with it in the future which is what ties into how vaccines work. Because they're prepping your body basically for the real thing. It's honestly amazing doing this research for this video made me so proud of my. Dang legs and arms and body. I've been having recently just literally breathing the oxygen and look at my legs and being like you fricken vessel. You are so amazing because like right now just looking alike like actually like right now. All we can do is mitigate this disease and virus while our bodies brilliantly using our T. cells and cells and macrophages these tiny little cells. That you all have it in you. Go out hunt down. The virus do their best to save you that is all we have is the physiology and this complex nuanced form of evolution where they literally like read the virus and then start to figure out how to proliferate and build this immunity. And I think it's just vaccines are so fricking brilliant. They're beautiful beautiful amazing things that humans were able to think of which is like unfathomable to me. That people were able to think that this about this immune system this detailed but they're brilliant pieces of like human technology like medicine that we are so to live and how it's been around for a while the idea of inoculating people in the video. We talked about the first vaccine sort of being in. I think the seven times. I'm forgetting right now. But even before that different societies were using the technology not technologies but they were inoculating people with understanding that. If you expose someone in certain ways they build immunity maybe not understand the intricacies of it intricacies of it but humankind has been following these steps for awhile before the first official vaccine was created before they were they were seen the results of giving someone a disease and then not getting it again before they were realizing like what the immune system was doing. So we'd like evolve render stood at this all ties into the current vaccine. So there's now a nether type of vaccine. There's a few others. I just want to reiterate this sub unit versus the shot. Because we talked about okay live attenuated vaccines we actually get the virus and the dead buyers but sub unit vaccines which is like the flu vaccine are just pieces of the virus literally just the proteins that are from the surface of it. I think that's important for people to know because it's like people get scared to putting the virus in me and putting the dead virus in me but there's also some where it's not even that it's just like literally the proteins and the part that your body needs to read to learn about to then build more white blood cells and t cells around that. There's a way of doing it without even giving people the vaccine which leads to this year. Because many people can't get live attenuated vaccines anyway like people who have compromised immune systems and often children. They don't have the immune system yet so there are certain other kinds of axioms which sometimes aren't as powerful and have to be given booster shots. Because that's how I get regular community okay. Going into sort of the more new and experimental types one is called DNA vaccines and it also ties into something called. Mri Vaccines which are going to talk about today. Yeah so the Amarna vaccine that you may have heard of in regards to SARS Cova too which is name of the virus and covert nineteen. Which is the name of the disease that you got from the virus corona virus being type of virus yes corona viruses an umbrella term so there are many corona viruses. Sars the virus that we talked in two thousand three that like took over Hong Kong and parts of Toronto Corona Virus. So if you hear someone say Corona Virus Right now. They're probably talking about the one. We are all doubts. Yeah but it is an umbrella term but the MR and a vaccine is the one you may have heard about because they've already started human trials which is cook. Cook Cook as well ever happened before. Yeah obviously I mean. Under special circumstances they are so as a company called Madonna Right. Is that the name private company there are. I think about a hundred labs around the world right now working on all sorts of whether it be vaccines therapeutics deal with being sick versus preventative and Madonna has already produced a vaccine than now testing. They are doing their annual testing concurrently. Usually you have around two years of animal testing before you jump into human trials but because of the nature of the situation because of the nature of the technology which all kind of briefly explain now. They've been given the go ahead by the government to start human trials. Used those words coming from Your Lips Mitch and explain it to the people listening on. Yes ma'am so basically eminem are anti vaccines as far as I understand. Like the broad details. It's so you know before. We talked about putting a virus into your body to trigger immune system in this case. They're putting a sequence of into your cells. I'm Arnaiz Answer Messenger and we can't get so detailed on this right now because like I'm just using words and I'm a die. Ram kind of guy but I'm aren a yeah it's essentially coded when you. What your DNA CODE. Aren't has their own version. And so it's a code when we say code. We mean that code. We don't like your DNA like typing Takayama coating so these strands of information. Basically go into your cells and the hope is that your cells read them and produce proteins so the spikes we talked about earlier. Exactly so your cells start making these proteins. They use the they read it. They build your cells would normally do even with your own. Dna they would take it. Read it build proteins that your cell needs? In this case the rene has them basically building the virus spikes and as a result of that is still going to trigger your immune response and so your cells make the spikes and then suddenly you're immune immune response reacts but luckily there is actually no danger because those proteins have been made but there's nothing attached. Yeah there's no virus being given in and so for that reason. They have jumped to human trials in order to test to start the safety of it so we just making sure that these humans don't get more sick when they contract the virus. Don't get more sick just in general from having this being injected into them and so that's where they're starting right now they're going to be doing forty five individuals over the next two weeks essentially excited about two weeks ago so it's fascinating because it's a fascinating example of like the. Times you're living in where we are like super speeding through science and honestly like I think it is important that we know the importance of this. Spiky spiky little Miss Rona as esquires call. It is easy and those. Spiky spiky proteins are very important. Because that's the thing that your body goes ooh spikey spike. He's not supposed to be here and they try and fight it off. So those spiky spike's are what we tying to our bodies you learn how to predictable and when we got to have seen. We injected into us. We're GONNA be injecting the spike. You Spike's okay. We're GONNA plaka understand this. I sure because you see this. When you see the krona virus being shown to you on popular means so Spanky Spank I was gonNA. I was GONNA emphasize to that. Just because it's not an actual virus going into your body. I mean that can't have some adverse reactions effects which is why they have to take so slow. Typically vaccines take like a decade or decades to make any approved because you have to go through so many stages of making sure that not only will this not only will this vaccine not 'cause say illness or other issues in a person long term but that it also doesn't inflame the issue more when you actually catch the virus so they can't just go boop okay took a week and you're fine. They now need to wait until you can the virus and they can't ethically just give you the virus so they basically have to wait but you back in the population compared to control groups who weren't given the vaccine and then see okay. Did it help you? Did you knock at the virus? The virus did you get the symptoms or your symptoms worse like there's still all these variables that can't be certain and that's why vaccines take so long to be approved because it's a pretty big deal to stick something in your body like that and hope that it works if it hasn't been rigorously tested. Yeah so less of a break and then we're going to come back and talk about how vaccines are usually made for people to actually use and how long we think this one is going to take so in order to do this. You're gonNA press what's going to press the the little like this can be. Outbreak.
"19 vaccine" Discussed on Sidenote
"That like you're like you know what I mean if they're able to control like twenty five thousand people's emotional feeling and powerful and amazing and so. Yeah you're the musician do I. I just like I want you to play live music because you could actually the skill to do that. I mean I don't not want to buy live music. I just don't have the time I by the end of the day I'm exact and now I'm in isolation so I can't play live music. That's something we humans have lost. All of this is the joy on. Yes but I mean I personally love concerts. I love when the spring and comes around and start figuring out which concerts I'm gonNA grow too because it does provide in my life like a euphoric experience outside of drugs and alcohol although both are usually involved but Yeah that's something that the world I think is missing right now. You've probably care less because you actually don't like going to live concerts for me. Are Very claustrophobic. And very hot and sweaty and so enjoyed a seated concert because then I finally get my personal space. I don't have to worry about crowding and pushing to the front so I enjoy live music in the right setting. Yeah Mitchell like seated and when I say no I'm not going with whereas sweating when the when the strobe lights hitting my face and I'm just like rubbing up against people and my shirt actually worst nightmare when you say yes I was GONNA say. We went to Patterson I I really loved it but everyone is sort of back and was like between my friends admit I go back and forth and he was like they think they're wondering if everything's Okay and it was like. I'm having a lot of fun I I'm having more fun back here then I would be if I was up. Everyone I literally like can use to love to crowd surfing. I used to. I honestly I was like really enjoy taking them out and marching on fire and I used to full on like mosh pit like Hirsch like like really starts dom violence and I do not approve of that he no. It's consensual violence because you join and then everyone's like teen angst and I used to. I would I would be like me to someone I would. I would crowd surf to the front. Get DOWN RUN BACK TO MY FRIENDS. Be like lift me up brew. Crowd serve the front. I would listen. How do we end up together? I remember like my friend. Doesn't memory loss each other at a concert? Mashing so for can heart and we couldn't find each other and I had this moment where I was crowd surfing and then I like saw in your living lifted to the Friday before we topic. We are going to jump into some studies vaccines and talk. Broadly about it so we just studied..
"19 vaccine" Discussed on Sidenote
"Today we are talking about vaccines. We are going to explain how they work. We're GONNA be talking a lot about the cove in nineteen vaccine where it's at and most importantly. Brenner talk about when we can expect to have one to inject into our arms. Ok Okay okay. Hey it's Mitt. And it's Gra decide. No we are actually crazy using some new equipment. That was a live sound of controlling on this little new unit so all the sound effects are going to hear today are pushing buttons and going live instead of having to edit it later and raven filming it to put up on youtube the place we make our money from. We'll see. This is the task so we have set up this little podcasts. Little studio in our home with this road equipment that we have been meaning to set up and are excited to test out row. Thank you are not like the road. Have this little device as a I. I'm using excited. It's fun to play with new equipment and still sounds good. The equipment looks like I don't know if you can come with me on this journey right now but it looks like the thing that Konya Westwood perform within them are my dark twisted fantasy nightmare era where it was like what. What do you address or Lady Gaga at the Brit Awards when she did Alexander Bridge Delay? Free Free Free Bet. Bet that's deep on Lady Gaga Fan. Or like grimes. And if that's not your favorite performance by her you a true fan. It's those things that like. Dj's US where you're like what you're doing is so easy. 'cause they go like come on guys and then they literally process. That's here's what they're doing and now I realize it is what we're here. We're fully locked up in self-isolation we've been for ten days. Eleven even counting. You haven't been I kind of lost track and just kinda living in it. It's March Twenty. Four th so that's where we're at with the information about covert nineteen and star. Cove too so. That's where this information is going to be coming from. But how are you feeling locked in our home? I don't mean this to come off the wrong way but I think of handling it better than you own. Well okay I think. Naturally I'm more of an introvert and more of a homebody and I can tell in your body's sometimes that you are like pent up energy and the other day you were like I just got like what. Just handsome downstairs sweating. I can hear you dancing so hard adhere to being like like. Maybe you're working out and he's starting to go crazy. Okay fine I definitely have been jumping on the bed like a child and usually you go to bed really early and you're so so much energy at night. Yeah I can't fall asleep while I mean I'm just thinking about the demise of I don't know the economy democracy at the end of the world. No I'm kidding. I don't panic although we'll talk later about some aspects of panic but yeah I know I definitely have a lot of energy in in your right in an average day. I'd say I'm outside more. I'm doing more than you are. So Yeah Energy has to go somewhere and now goes into me screaming into Appello for like thirty s and I can see that other people online. There's like the two factions of people who are like. This is my normal life. It's not that different. Especially if you work at home in the first place I can either people that are like wow much longer. Does this have to go on? I can tell that I'm obviously like annoying when even my dog. Who's a golden retriever? Seems annoyed by my energy like okay. I'm actually like more annoying. And a golden retriever puppy. Okay well but I do suffer from film and I find that. It has helped me a lot with my film. Oh because now I ever see that friends or hanging out without me on like online for example it means that they might die like you know what I mean so. I'm just like that's actually really nice. I like this is what we're all doing and if you're not you're actually lives at risk and I don't WanNa be there anyway. So it's like I don't have to worry about that. I've never really had like you know ticket here. You go to stay at home and do nothing fair enough okay. Well we're GONNA talk a lot more about vaccines and what's going on. But first we will jump into what we learned this week. Hit the sound fun this week. Our Right Wow Mitchell I get your What did you learn this week? So my what have we learned this week as a bout vaccines. Oh Nice so yeah. We still are receiving the magazine nature into our little mailbox and I wash it front and back so all. The pages are like landline. Destroy Destroy running it under the tap with soap and water related to cover in this mostly ads for like pharmaceutical drugs on the first three pages on how so what where they're at with studying on animals. I realize that a lot of these studies talk about injecting vaccines when you're testing for them into ferrets and actually in our video we talk about how a really prominent and exciting SARS vaccine. This is from two thousand three not the most recent SAR. Copd to the one. We're talking about SARS vaccine when they injected into ferrets and gave them the disease they had actually made the disease worse and I was like very. It's weird like you usually hear about my son monkeys. And it's because fair it's as animals have the most similar lungs physiologically to humans. But Yeah so when they study that. I know I know so I. I didn't know that either even though we talk so much so many of the studies I was getting what I didn't know why I mean but it explained in this article and then also reading the full study I found that Rhesus Macaque monkeys can get covert nineteen and they can be infected with the virus but they don't show symptoms In the same way we did. They don't show the same sort of severity of symptoms leading up to pneumonia. They just ended up with pneumonia so rhesus macaque monkeys do got pneumonia when given the virus. So that's that's but there's no like warning warning there's like no whereas most people have shown headaches and low. Yeah so but they can still got it. That's good that's promising. We can use the vaccines on them. And then mice can't get it but they can genetically modified the mice using a protein called ace to inject the mice with a virus and the mice will get pneumonia so we can now test on my so. These are the animals ferrets mice and Rhesus Macaque monkeys. We are starting to actually test on test on inject and learn about these vaccines. That's really fascinating. I honestly did not know that. I think I've heard often that pig bones are the most similar to human. I don't know if that's true but I have heard that and I think it's because people also find pick bones. I'm not sure if it's human bones but I think that's like a CSI kinda thing or are they use it for like two. I don't know why are you looking at that? I was like I'm literally looking down the barrel of the camera because there's a camera here and I'm a youtube or and I'm just like and subscribe and we'll see you next video. I was hoping you'd back an answer either way. It's interesting different animals but have different attributes to best motto after humans. That's fascinating so this week. I learned something unrelated to vaccines and it has to do with music and it has to do with listening and watching it live performances of music. So we know often and you probably have experienced this physically that if you're listening to a live performance say you're at the symphony or even just watching a band. You might move your body you might. You might get physically into it and those cry or cry but those types of physical behaviors start to sync up between both People who are performing and people audience not like exactly sink. But you know you tend to sway the same way hit the beat and so they've just done some research on the neurology of that and they find people's brains are actually firing in the same way as the musicians Which doesn't seem so shocked. It was just really cool study. They basically had them use it. In this case it was a violinist and the violinist played a handful of songs and recorded it while their brains were being also recorded violin. Like are we talking like Irish like shit downturn or is it like you're playing a violent like it's Qatar down here no it was up here? Have you ever heard of Ashley mcisaac in front of your belly button? I don't know what it was but like it wasn't a rocker. I assumed it was in class. Murphy's Acor just either way they were giving the instructions not to show much facial expression so that the viewer wouldn't know if they were really enjoying apart or not and so what they found was that regardless of the physical cues the violinists themselves would be anticipating exciting at certain areas of the song and as a result their brains would light up and that same thing would happen in the listeners as well even when the violinist was trying their best to not sort of moat. Yeah so it was all about the experience of the music together being really well. That's also probably an. We've done a video on at this point in her life. It's like we're doing this for eight years. My friends When we did our video about pop music and how it works on your brain. It's all about patterns that your brain picks up on and then when those patterns shift or you predict the pattern. That's when you get that release of dopamine so I guess regardless of if the violinist decided to change their body your body both your body's are picking up on the patterns picking up on the shifts and that's why music is so amazed powerful. Yeah I think I was thinking how interesting and cool it is to be the musician who is in your own way controlling the brains of other people not controlling by going on this journey like you picture music building to a climax to the drop or whatever it is whatever genre just popped up. That was so popular like the drop. There were so many still not in the same way. I don't think but I think that's so interesting that as a musician. You're feeling anticipation excitement. And you're sort of giving it. Why also we all many of us really idolized that feeling that idea? We glorify like imagine what it must feel like. It's kind of religious in many ways like Ariana Grande is like the most famous pasture of time or master. I don't know how to say pasteurized milk pastor in the sense..
"19 vaccine" Discussed on Marketplace Morning Report with David Brancaccio
"There are at least eighteen companies heart worth looking for something that knocks down or Vaccinates Against This virus. A Massachusetts Company called Moderna sent some test vaccine yesterday to federal health experts in Maryland with hope for a human trial by maybe late April and stock in Gilead Sciences rose nearly five percent yesterday after the World Health Organization said one of Gilead existing drugs might help treat people with the corona virus on the vaccine. Front let's take a visit to a lab in London the BBC's Stephen Ryan filed this for us. The race is on and scientists at Imperial College in. London have been hard at work for the last month on a vaccine. It's built using a gene sequence provided by researchers in China has Dr Paul McCartney a vaccine Manala just explains we made the vaccine within two weeks and then the next week we put it into animals. Just being very quick usually. It would take us months to do that. So let's talk science back in his office. Dr Mci Taff me for the name comes from Corona virus is called Corona because it looks like a crown so it looks like it's got little halos on the outside and it's that exact halo is the thing that we have got sequence off and that we're making the vaccine too in short what you now have goes through a process of reproduction so you can deliver it as the vaccine but who will do it. Some of the Pharma giants including Glaxosmithkline have decided not to develop their own for now. Dr Thomas Brewer Chief Medical Officer. Gsk Vaccines Explains why the current outbreak since modern eighteen companies work on vaccine candidates fee believe developing yet another vaccine candidate would be less advantageous for the word. The Time Horizon Puskas of developing vaccine are hard for companies to shoulder. Take your vaccine. For example companies were only able to get approval from regulators late in twenty five years after the crisis despite substantial investments in research and development only now is the vaccine available for Corona virus. Gsk along with Sanofi are still involved in the process. They're sharing their technology platforms with developers. Who are working to bring the vaccine to market. Meanwhile back at Imperial College Doctor MCI is hopeful that then of success and soon and no. It's not as simple as sharing scientific formula to speed up the process. Different labs often make different kinds of vaccine at appeared college. They've been developing technology for the last three years that helps to build vaccines more quickly. And that's helping to speed up work on a corona virus vaccine. I wouldn't like to consider it to be a race or competition. I would prefer to see it as a clever of race. It's not that we're setting out to be the first or that. We think the vaccine will be the best. One of our personal goals for our team is an exercise to see how quickly we can get into human clinical trials scientists. Here hope to begin. Human CLINICAL TRIALS IN LATE. May or early June after that it up drug companies to license a vaccine so it can eventually reach the shelves of pharmacies across the Globe in London. I'm the BBC's Stephen Ryan for marketplace the marketplace morning report from APM American public media..