UK doctors to trial ibuprofen in COVID-19 patients with breathing difficulties


Now now we we know know there there are are many many scientists scientists all all around around the the world world working working on on a a vaccine vaccine for for corona corona virus virus and and we we also also know know there there is is no no single single proven proven treatment treatment for for it it so so there there will will be be a a loss loss of of interest interest in in news news that that a a U. U. K. K. clinical clinical trial trial is is looking looking at at whether whether ibuprofen ibuprofen could could work work the the anti anti inflammatory inflammatory drug drug which which has has shown shown great great promise promise in in initial initial tests tests on on animals animals will will be be administered administered to to those those with with breathing breathing difficulties difficulties that that speak speak to to professor professor metalsmith metalsmith who who is is director director of of king's king's college college London London center center for for invasive invasive therapeutics therapeutics that's that's one one of of the the bodies bodies working working on on the the trial trial welcome welcome to to the the program program I'm I'm sorry sorry but but just just getting getting you you to to outline outline for for us us whiny whiny should should be be there there were were fears fears that that ibuprofen ibuprofen could could actually actually be be detrimental detrimental in in the the treatment treatment for for corona corona virus virus hi hi good good afternoon afternoon yes yes there there were were some some initial initial concerns concerns raised raised we we have have concerns concerns rise rise from from from from the the French French health health ministry ministry and and there there was was an an article article published published as as well well which which which which really really laid laid out out the the theoretical theoretical concerns concerns and and you you know know it it it it is is important important to to consider consider however however what what happens happens afterwards afterwards was was that that there there was was a a review review of of the the evidence evidence including including a a review review of of studies studies that that looked looked at at earlier earlier infectious infectious diseases diseases like like birds birds I'm I'm the the first first Sauls Sauls was was what what is is the the current current head head that that make make and and they they concluded concluded there there was was no no evidence evidence that that this this drug drug could could increase increase the the chance chance of of an an infection infection taking taking hold hold was was sind sind symptoms symptoms and and this this yeah yeah there there are are statements statements released released from from the the World World Health Health Organization Organization the the European European medicines medicines agency agency and and also also the the U. U. K. K. commercial commercial medicines medicines also also released released a statement a statement saying saying that that there's there's no no evidence evidence of of of of home home here here okay okay so so tell tell us us then then walked walked there there is is that that suggests suggests that that type type of of pricing pricing could could reduce reduce inflammation inflammation and and in in the the lungs lungs trolls trolls so so well well there's there's no no there's there's no no evidence evidence of of home home in in order order to to demonstrate demonstrate benefit benefit we we have have to to do do a a trial trial so so why why do do we we think think that that this this trial trial is is important important well well I'll I'll be be pricing pricing has has been been suggested suggested as as a a treatment treatment for for the the respiratory respiratory distress distress that that you you can can get get with with carpet carpet nineteen nineteen disease disease for for a a long long time time in in fact fact prescription prescription dress dress distress distress in in general general but but can can come come from from other other infections infections and and other other lung lung diseases diseases as as well well coming coming all all the the way way back back to to the the nineteen nineteen eighties eighties and and this this is is mostly mostly in in animal animal models models now now they're they're all all concerns concerns with with all all of of your your preference preference side side effects effects you you know know it's it's not not super super tolerated tolerated drug drug if if for for example example you you have have ulcers ulcers we we don't don't risk risk of of gastric gastric bleeding bleeding so so this this particular particular formulation formulation on on record record from from where where you you sit sit is is a a lot lot safer safer and and you you also also have have a a better better buyer buyer distribution distribution in in the the body body so so it it can can enter enter the the immune immune system system S. S. as as well well and and in in the the animal animal models models which which of of my my struggles struggles of of acute acute respiratory respiratory distress distress syndrome syndrome the the survival survival in in the the months months goes goes up up dramatically dramatically when when a a given given this this unique unique formulation formulation of of ibuprofen ibuprofen okay okay I'm I'm what what I'm I'm what what that that will will do do it it would would be be a a formulation formulation be be given given once once it's it's established established that that you you have have covert covert nineteen nineteen Sir Sir do do you you know know this this is is this this is is very very important important so so this this is is not not something something that's that's going going to to prevent prevent you you from from getting getting the the disease disease a a toll toll and and in in fact fact this this is is specifically specifically targeted targeted at at certain certain symptoms symptoms which which we we think think are are in in the the mid mid disease disease stage stage so so we're we're really really looking looking at at patients patients who who are are hospitalized hospitalized and and the the way way they they would would receive receive the the drug drug is is actually actually very very simple simple to to just just be be in in capsules capsules is is warm warm truck truck so so we're we're all all used used to to argue argue pricing pricing is is not not like like that that but but it's it's toward toward drug drug okay okay well well we we wish wish you you all all the the best best with with the the at at the the trial trial professor professor Mifsud Mifsud messa messa a a director director of of king's king's college college London London center center for for innovative innovative therapeutics therapeutics one one of of the the bodies bodies working working on on that that U. U. K. K. trial trial to see if I'd be profane can be amongst the treatments being given for patients who are suffering with credit nineteen

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