A highlight from 385 What is the Best Form of CoQ10?

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Oh thanks for having. I appreciate your taking the time i've been so interested in this particular nutrient ever since. I first heard about it before we get into that subject though tell our listeners a little bit about your background your history and how it is that you got involved with konica and with coq ten director of scientific affairs kinda us. And what i do is address. The built and implementation of clinical trials throughout the us of major medical center by the phd Hd is in Chemistry and biochemistry. I did my post doctoral. stinted harvard. And then there's also a steph researcher at harvard for about Eighteen years in pharmacology and biological chemistry buzzer staff member. During that time. I did quite a bit of work on free radicals in metabolic systems biological systems and actually worked with co q. Ten is long ago. fifteen years. I was introduced. Conaco a little over a decade ago when they asked me to come down and talk with them and that's when they were first looking at that new form which is called ubiquonol. Well what kind of a company is konica is co q. Ten their main focus or what are their broader interests as well as a scientifically based company. They've been around since i believe late. Nineteen forties several divisions including a food division plastics division to eletronics in a life science division. The life science division is split up into medical devices. We do pharmaceutical intermediates. And of course nutraceutical. Konica is the largest manufacturer of co q. Ten in the world. They were the first to introduce it. Commercially almost forty years ago. Well that's quite a history and quite a legacy so certainly you are the right person to talk to. Let's talk about co q. Ten and its role in human nutrition. And why is co q. Ten so important because of its metabolic functions first of all is present in nearly every cell tissue and organ. are we actually biosafety. Cise coenzyme q ten and it has a number of metabolic functions but probably those that are most focused on is its role in energy production and also as a very strong lithosphere. Soluble antioxidant for cellular protection. Tell us a little bit about what these functions are in terms of energy production this on a daily basis even if you're sedentary everything that's going on in every solve your body metabolic -ly requires an energy exchange so the might the congress of the powerhouse of the cell actually produces up to ninety five percent of the atp if you'll pardon development of energy in our systems co q. Ten is actually one of the critical components in the production of atp into my time. So i called co enzyme q. Ten electron transferring agent in what's called the electron transport in michael congress so literally chapels electrons from what's folks complex one and complex two complex spree in this particular chain that is critical in a production of atp in every cell in our body. So if you have low levels of coq ten that means you probably have an energy deficit ubiquonol. Nice to have it's critical. Why would people be low and co q. ten what are some of the factors that would influence those levels. Actually i'm glad that you brought bat brings to light is the new form of coq. Ten that you'll looted to in your introduction and it's called ubiquonol with conventional coenzyme q ten and that's what i'll call the coq ten that's been on the market for at least the last thirty years in by the way is one of the top ten sellers as a natural product for that time period. That's never wavered. And for good reason it works. There's thousands and thousands of publications that have been produced publicized co q. Ten minutes health benefits. And i should add by the way that at least ninety nine point nine percent of those studies were done with konica co q. Ten differences is that you all the new form that has come out is. What's all the reduced or electron reform of co q. Ten it was introduced in two thousand six commercial each the reason it wasn't introduced before two thousand and six is that history deuce form and when i say reduced means because it's electron rich is very sensitive to light air so that oxidises readily so it wasn't a mental being put into bills and soft skills like conventional coenzyme q ten the oxidized form which I'm calling conventional coenzyme. Q ten is what most people have been familiar with over the past thirty years and has bought a pair of local health stores. One of the that we found out now is that the actress form in the body is actually reduced electron rich for you could use conventional science you ten because it's actually regenerated body. The caveat is is that if that was constant and consistent and efficient through our lifetime than conventional oxidized to ten is a supplement would be just fine but what we've learned since ubiquonol has been made commercially available. And by the way i should add is partially available means not just as a supplement but also available to researchers is. There's a lot of research that's being conducted with small and has done promos past decade. So we're kind of catching up with the publications that have been done on conventional coenzyme q ten but what we've learned is as we age consistency and efficiency of the conversion of the oxidized be active reduced born in our system. Not just in our system in any aerobic cellular system diminishes with a so that necessarily affect the production of energy within the aerobic cellular systems including our body to the point that with aging. Don't just normal age as well. As with acute and chronic disease therefore with the efficiency of the conversion of the oxidized because the electron rich active reduced form diminishes significantly and what has been found in a number of studies. Is that the health benefit that we've seen thirty or four years with conventional points. I'm few ten were within subjects. That's still has relatively efficient conversion rates. We didn't know that that we know that now to the point where people who are familiar with publication health benefits of co q. Ten had seen a large number of positive studies but there's also a significant number of studies that have been on the fence and new tool quite duplicate those previous studies. There were two reasons for that one. Was that those. Were very low at that time. That were administered. so that's helped critically. The difference was and specifically was that they were not able to convert their body wasn't able to convert the oxidized. Conventional culture tend to the active form as efficiently. And so that's why we see. Some of the differences in some of those studies came out the reason we can save. That is now go back and duplicate those studies. We find that especially with critically ill. People are older individuals No matter how much conventional coenzyme q ten. They were administered and. I'll give some examples later from trials. If i have time. It really didn't make a difference. But when they were giving ubiquonol

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