The Skeptics Guide #807 - Dec 26 2020


Everybody cara santa. Maria audi jay. Novella bella guys evan bernstein. Good evening folks and making his debut in callanan in welcome for the guy man. I need a cool intro. I don't have one and that your intro. I need a call one and you got to come. It'll come to you go okay. Sorry there is an s. She you holiday tradition that when we do our end of the year. Wrap up show for a number of years. We had on mike lasalle. Who worked issue for years to great friend of ours. Unfortunately we lost him a number of years ago because of heart failure due to a congenital heart defect. And you know what occurred to me. It's like you know he works for the show. And we should resurrect this tradition. Because it's fun here here. So resurrect mike. But that didn't work. i mean it. Is chris cool with the resurrection of easter. You guys lame to and this is of course our year end review show where we talk about all the wonderful stuff that happened in the look on events. Twenty twenty we shows twenty twenty. Wrap up for a long time will never remember twenty twenty for anything now. E-education people out there who don't know who you are. You are often the disembodied voice that manifests when we're doing live streaming events like the friday dr streams yeah and you have been in a valued asset to the s g. We basically make all the technical stuff happen. You have to say that. Because i'm here though but yeah i because this is true. I'll do it all alone. I mean it's not like standpoint my finger around you know he's actually what you did winning. Just tell ian to do stuff. The finger pointing begin has made himself indispensable which is great but it's also like jane. I occasionally godfrey in weren't here. We would have no idea. Newsletter i mean when in came aboard he enabled the dramatically increase our quality and our output. Union is a heavy heavy lifter when it comes to technical stuff. It's amazing. i just love watching his brainwork as an example the the twenty the twelve hour shows you know wants to be a twenty four hour. Show wrong with you. In january january twenty third is going to be all green screen and that would only possible because an is going to manage the whole green screen thing for us through this weird things. I mean the practical set goes beautiful. And i hate that. I am partially responsible for destroying it but the green screen this is going to make like the world of difference with all types of weird tech stuff that will do. We haven't destroyed our practical that we can't bring ourselves to do it quite formerly behind green. It's just behind the green screen. And as i told jay down to it and say the green screens just rocked so hard that we're like we're never gonna do anything else except unless we volume but we'll stick with the green screen forever. That's get rid of the practical star trek console said. I said we're never going to destroy that at the very least we'll sell it have somebody. Hey you come pick it up dismantling pick it up and it's yours of course pay us. I mean right. Destroy onate against the law. Well he gets the law head of ourselves here all right. So let's get into some of the categories that we talk about for review show. We're going to start with the science of the year. Science news items into the. What was the science news that had the greatest impact Either on us personally on skeptical movement on the world and the thing is there's one giant big news stories zaire creek hornets. All out of the room and murder. Hornets got a lot of votes. By the way come on. This was the year of covid nineteen vaccine for me. Yeah it was the vaccine. It's the sequencing sars cove to. It's learning everything that we could learn about it so quickly and developing this vaccine i took i took a good look at this Trying to just trying to see how. What did they actually do. How how dramatic was it. And it is quite dramatic. I mean most as you probably heard most vaccines take ten to fifteen years to make mean. That's a good average. Some of them are even longer the the influenza virus several strains The took twenty years to develop on chicken pox. Twenty eight years to develop and then fifteen years for that. Peplum virus rotavirus fifteen years to develop that and the up until now. The fastest that i could find for vaccine development was for the mumps which took four years. If that took four years now i mean that would oh my god my pandemic hair would be so horrible and do remember that i mentioned on the show. How long did it take to develop the vaccine for covert you remember. Oh it was really sure like insanely short tax. You mean to once we had covid fully sequenced and we understand it. How adapted but it depends. I mean what kind of foundation technologies were already in developing. Of course they had they had to found. They hit the platform they had the foundations. But from the moment that maternal. Let's say got their hands onto sequence of the sars cov two virus from the chinese. How long take them now. I think of these two days. Yeah that is. That's that's where we are now And but here's why. Here's why i looked at that specifically a why. Why is it so fast. Some of it. One of the reasons is because we're just simply better. We're leveraging our recent successes. We have accumulated knowledge that played in we also phases two and three combined for expediency and as was demonstrated in the current trials. So instead of you know phase one two and three or one is safety. Efficacy three comparison. We- they combine two and three that sped things up but that was after the two day thing we're talking about know about you have the code and now it's being distributed. I'm talking to full the full monty. The the whole thing and also large scale manufacturing can begin when the vaccine is still in the trials and that cuts a ton of time off. So that's that's the why. Why wasn't so fast. We're better reason the other reason the why it's so fast. It's it's purely. I think because of the advantages inherent with of pfizer moderna rene vaccines or developed so fast. Partly because you. They don't need companies to really to produce the protein of the weakened pathogen for the vaccine like we used to Basically you're making the murray in a lab and that and that could take months or even years off of the process so that the fact i think the fact that it was an mre and not this weekend and not as weakened version or or segment of protein from the virus that i think is was a dramatic increase in the speed and another factor. You don't really hear too much about is that they were exceptionally swift at recruiting patients for clinical trials. They got together much faster. So i think so all big it really easy to recruit patients when there's a pandemic daily there you go hundreds of thousands of people coming down with the with the with the illness that you're studying but also but keep in mind though bob so part of it was the whole feature of vaccines is. They're fast and not necessarily better in terms of efficacy. Or they're good facts notwithstanding. I mean some regular vaccines or ninety five percent of effective but as the advantages we're really good at making genetic material dna cetera and so if we can be if the vaccine production process is just a matter of sequencing a gene gene or or protein and then making an mr. Rene that's it literally takes days to all. The other. Time was testing but bob we have to point out.

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