Dr Narrow, Dr Liu Ignarro, Nobel Prize discussed on Broken Brain with Dhru Purohit
. Welcome to the broken brain podcast where we dive deep. . Into the topics of Neuro Plasticity, , EPA genetics, , mindfulness, , and functional medicine I'm your host droid and each week my team and I bring on a new guest who we think can help you improve your brain health feel better and most importantly live more. . This week's guest is Dr Liu Ignarro. . Dr Narrow is a medical research scientist who was awarded the Nobel Prize in medicine for. . His breakthrough discovery of Nitric Oxide, , N., , O. N., , how it positively impacts health and longevity especially hard health his groundbreaking research on nitric oxide pave the way for among many other innovations Viagra. . A Very well-known medication to a lot of individuals were recently by the way nitric oxide is currently being investigated over the world in hospitals and universities as a possible treatment and intervention for. . COVID, , nineteen Dr Narrow is a distinguished professor emeritus of molecular and medical pharmacology at the University of California Los. . Angeles and he has his PhD in Pharmacology with over thirty years of experience in teaching doctor Dr Welcome to the brokering podcast. . It's an honor to have you here with the honor is all mine drew. . It's great to be here and I really look forward to. . Talking about good health effects. . Absolutely, , in preparation for the interview, , I was listening to pretty much all your content that I could get my hands on online and I've seen you mentioned in numerous. . Speeches and talks about. . Teaching is so central to who you are nothing fires you up more than explaining concept and then seeing a student that light bulb moment where they get it and I just want to say where did that come from before we jump into everything we're doing a passion for teaching come from while I can tell you clearly my passion for teaching, , which is every bit as as large as my passion for a discovery or original research. . My my passion for teaching came early when I was in elementary school and high school and you know why? ? Because I had lousy teachers and I would always sit there and wonder why can't these people explain something better than what I could. . Read in the Damn Book. . You know they're there to teach your up in front of the room teach and impart your information to this edens so that we can understand it and I swore that if ever the day came when I would be a university professor, , I would not do it their way. . I would do it my way and try to become the best teacher I could, , and I've always had this passion for communicating with students <hes> I love that that's incredible and we'll come back to that. . In your origin story. . I want to take a moment to congratulate you because we're coming up on the twenty second anniversary of your Nobel Prize I believe you got the prize. . In October. . Twenty two years ago. . Does that sound right? ? You very good at this very, , very good. . Yes. . I the announcement of my Nobel Prize was an October twelve. . Of One, , thousand nine, , hundred, , Ninety, eight, , , and you know this coming Monday October fifth the Twenty Twenty Nobel Prizes will be announced. . So get ready. . You one thing I don't know who's going to get it. . But I'M NOT GONNA get it a second time. . That one is enough. . One is fantastic. . Especially one as powerful as the one that you've gotten, , we should awe only hope and dream that we can have direction i WanNa talk about your basis of the work for receiving the Nobel Prize for discoveries concerning nitric oxide as a signaling molecule in the cardiovascular system. . Let's start off with the basics what is nitric oxide and how's it so fundamentally related to our health and function. . That's a great question would require a about a week to answer but I will try to do it in a couple of minutes. . Nitric oxide firstly, , I want to remind everyone is not a gas I I mean is not a liquid or solid, , but rather it's a gas. . It's a gaseous substance that only lasts for a few seconds. It's . very unstable. . This is what made it so difficult to find in the <hes> in the human body, , and that's why the discovery came. . So late in the nineteen eighties and so essentially. . What I discovered was that our bodies produce this molecule of nitric oxide which should not be confused with nitrous oxide. . That's laughing gas, , and that's what's used in a dentist office, , for example, , to relieve pain. . Nitric oxide although it sounds the same is a totally different <hes> molecule and. . What we discovered was that our arteries, , our endothelial cells that line the arteries actually make this nitric oxide and what nitric oxide does is phenomenal. . It's Vasil later. . It widens the arteries and when it does that it lowers the blood pressure, , it improves blood flow to different Oregon's was your dilating the arteries and. . In addition, , this nitric oxide can keep the inner lining of the arteries healthy so that blood does not clot a when it's not supposed to in the arteries also prevents cholesterol plaques from depositing in the arteries. . So as long as you keep making nitric oxide in those endothelial cells, , it will keep your vascular system very healthy. . So one of the reasons we make nitric oxide is to protect our cardiovascular systems against high blood pressure. . Stroke and heart attack. .