Madison discussed on Both Sides Now

Automatic TRANSCRIPT

The disease this is where we get our hints about what would be a good drug target what most basic scientists have been doing in the past is using the male animal in models of disease male animal models or cells from these animals and that in the past is using the male animal in models of disease male animal models or cells from these animals and that has bias so hold tight line four drugdiscovery toward what's optimal for the male up until recently there's been absolutely no guideline at all or requirement really requiring investigators gutty novel therapy on male and female and male and email animal had a majority of therapies that are developed from its infancy are much tested on male fellow or male animal about it hadn't makes it to the human studies we know that it works very well males we have no idea and email seldom female animal so this represents a problem for clinical trials because at the most expensive end of the spectrum human clinical trial is often times the first time at thing evaluated and female now you might expect that there would be differences in animals between males and females but a lot of basic scientific research is done on cells skins cells heart muscle cells kidney cells and so on you might not think there is much difference between the male and female versions of those but would roof says think again what we're talking about fundamentally are the sex chromosomes x x an x y and that imprint of the chromosome affect can have profound effects right at the cellular level so we how decision medicine are personalized madison and the rise of genetic madison and the biggest difference between the genome the x and y chromosome content precision madison are personalize madison and the rise of 'genomics madison and the biggest difference between the genome the x and y chromosome content so this is something that i thank once the.

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