Republican Party, President Trump, Donald Trump discussed on Weekend Edition Sunday

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Wind advisories going into effect today. This is weekend edition from NPR News, Luke Garcia Navarro, shortness of breath and a dry cough are often tell tale signs of covert 19. But even early on, doctors realised the virus can inflict all kinds of other damage from strokes to strange rashes. What do these symptoms have in common? As will Stone reports, Many researchers are focused on how the Corona virus sabotages our blood vessels Picture a skating rink before a hockey match. The top layer of ice is glassy and slick. The players and pucks glide smoothly across. Dr William Lee says that ice is like the lining of your blood vessels when you're healthy. But during a Corona virus infection, the virus damages the inside of the blood vessel in shreds the lining that's like the ice After hockey game, the lining becomes ragged and leaky Things start to get stuck and you wind up actually having this situation, which is really untenable for blood flow. Lee and an international team of researchers compared the lung tissue of people who died from Cove in 19 with those who died from influenza. They found stark differences. For example, the covert lungs had nine times as many tiny blood clots. The surprise was that there's a respiratory virus that gets into the lung makes a beeline for your vascular and Ophelia cells. The cells lining blood vessels, thes Endo feel your cells are a vital part of the vascular system, coating the inside wall of every artery vein and cap Ilary. If the novel Corona virus is reeking a special kind of havoc on the end of filial cells, as Lee and other scientists think that helps explain why covert complications can appear anywhere in the body. The effects on the brain the blood clots in along and elsewhere in Analects, the cove in tow the problem with the kidneys. And even the heart. Early in the pandemic. Doctor Gaetano Santilli saw how many different organs could be affected and he's suspected Endo. Filial cells might hold the key. Santa Lisa researcher Albert Einstein College of Medicine in New York City, he says, Consider what thes endothelial cells do in a healthy person, Mainly the interfere cell functions are to avoid high blood pressure and to avoid blood talking. But when these cells don't work properly, when they're dysfunctional, the opposite can happen. Santilli saw this with Cove it and realised if there isn't a dysfunction because of the minders, we can explain why we have an increased risk off blood clotting in prominent scientists aren't sure exactly how covert damages blood vessels. What's clear is the body's immune response often begins to spiral out of control. What we see what the star super rhinoviruses really an unprecedented level of inflammation in the blood stream. That's Dr Jurgen Conte of the National Institutes of Health. We start to get this relentless, self amplifying cycle of inflammation in the body, and that mainly to climbing. This is most striking in severe cases of covert. And doctors who care for these sick patients like Roger Swell to have come to see Cove it as a vascular disease. In addition to a respiratory illness Welt is a critical care and pulmonary physician in Southern California. Early in the pandemic, he noticed the patients who ended up in the I C U tended to have diabetes, high blood pressure or were obese. All those conditions can damage the blood vessels and cause inflammation. So if you catch the virus on top of that, it's a stress test. Ifyou're right on the edge, and you get the windblown from this Corona virus. Now you've gone over the edge, and he also noticed that the patients hospitalized with Koven are different from those hospitalized for respiratory viruses like the flu. They are having shortness of breath. But we have to realize that the lungs is more than just the airways. It's an issue with the blood vessels themselves. That's why Kobe patients Khun struggle to get enough oxygen. Even if air is being pumped into their lungs by a ventilator, Schultz says, even after breathing improves, some patients still have damaged blood vessels. There now off oxygen they can be discharged home, but they're vasculature is not yet completely resolved. They still have inflammation. So what does this mean for covert treatment? Doctors are already using drugs to manage information and prevent clots, though they're still working out the best combinations and dosages, But they're also looking at more direct ways of protecting and do feel your cells to prevent blood vessels from breaking down in the first place for NPR news, I'm will stone This story is part of a collaboration between NPR and Kaiser Health News. As Donald Trump tour through the Republican primaries four years ago, there was this question. Would he changed the Republican Party or with the Republican Party changed him. Throughout the program today were asking how the Trump presidency has affected institutions and the country and what another four years could bring. And arguably nothing looks more different under Trump's leadership than the grand old Party. Nicholas Lemon has just written about this for the New Yorker, and he joins us Now. Welcome. Thank you. Your piece is titled The Republican Identity Crisis after Trump and I want to stress that after isn't necessarily after November 3rd. Of course, there's an election coming and we don't know what the results will be. But you see an identity crisis in the party no matter what. How so So start with the 2016 campaign. President Trump blew away all of these much more established Republican candidates, however, then, in my view, at least he's governed as a very old fashioned Republican. If you take out the rhetoric and just look at the substance, very big tax cuts very big rollback of regulations reshaping of the courts for the Federalist Society. Yes, over 200 federal judge appointments. With close ties to ideological, conservative jurisprudence. So kind of the mystery of what's happening these last four years from that point of view is What's the future of the Republican Party? Is it the Trump of 2016, or the Trump as president, who was much closer to the traditional business wing of the party? Has he moved the party further to the right is Trump's simply saying out loud about immigration in particular, which is such a huge part of his appeal. But other hot button issues what establishment Republicans believed less vocally in the past. I don't think right and left are that useful in thinking about the future of either party at heart? The Republican Party for 100 Years at least, has been The party of business, and we used to think that meant it was the further to the right party because it was more about business interests, and the Democrats were more about labor interests. But you know that's not really true anymore because you make the point. Silicon Valley closely aligned to the Democrats and the biggest companies, not only in the world, but in the United States are from Silicon Valley, right, and you know, it's the Republicans. That have been waging rhetorical war on Silicon Valley, and now they're waging legal war by filing an anti trust action against Google, with one against Facebook supposed to be following its the Republicans who did that, not the Democrats You know, along with that the Democrats with a party of generous social welfare programs like Social Security and Medicare, and the Republicans were not. That's not true anymore, either. So I agree that he's moved the Republicans Implicitly to the right on sort of ethnic racial issues to more openly to the right on those issues, But that could change in the future if the Republican Party were in different hands. Well, you see three pass forward for the Republican Party remnant restoration and reversal. Revenant is a continuation of trumpism and you imagine Donald Trump Jr filling and his father's shoes? Restoration is returning to the party as it was before Trump and reversal you say is the least plausible, but the ones you spend the most time on. Can you elaborate a little bit. Reversal.

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