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Report. That they're covid. Nineteen shot may not only protect against disease but also help to prevent spread of the sars o. V. two virus the news was heralded by policymakers desperate to see a vaccine that can curb the spread of the disease but scientists have been a bit more cautious if confirmed the results would represent a breakthrough in the covid nineteen vaccine race so far the shots authorized or approved around the world have shown strong protection against moderate to severe disease but haven't definitively proven that people who get vaccinated are less likely to spread the covid nineteen virus but the data say. Some experts is confusing. So it's hard to adequately evaluate the companies claim that the shot can actually slow the spread of covid nineteen or not in the study published on the lancet pre print server which means the results have not been peer reviewed a gold standard for ensuring the scientific rigor of the findings astra zeneca and oxford scientists. Report that two doses of their vaccine was overall sixty six point seven percent effective in protecting against covid nineteen disease as part of its analysis. The research team also collected nasal swabs from and unvaccinated study volunteers in the uk every week and tested them for the virus. The scientists found that positive tests were about fifty percent lower among people who got two doses of the vaccine compared to those who weren't vaccinated because people who don't test positive are less likely to spread the virus the researchers extrapolated from those data. The astra zeneca shot can transmission of the covid nineteen virus. However that may be a bit of a stretch says dr carlos. Del rio executive associate dean of emory school of medicine. It's a leap of science. That i think still needs to be proven. He says what they show is that there was either decreased viral shedding or decreased detection a virus however they do not actually show that transmission was decreased. We can say less. Transmission is a possibility but the data on. That needs to come out says del rio. We wanna state the facts and don't want to overstate the facts. That concern was echoed by health officials. In switzerland who decided this week to reject the astra. Zeneca shot the data available and evaluated to date are not yet sufficient for approval. The country's regulatory bodies swiss medic said on february third part of the concern has to do with the fact that the astrazeneca study underwent a number of changes after the phase. Three trial was begun. A fact that some infectious disease expert say makes it difficult to interpret the results for a clinical trial as crucial as this one modifying the setup once it's underway is similar to changing the rules in the middle of a game the study originally set out to investigate a single dose vaccine but was changed to two doses when concurrently conducted early studies show that to set doses of the vaccine produced a stronger immune response further because of what astrazeneca said. Were mistakes in measuring doses. Some people in the study in the uk received a half dose for their first shot and a full dose for the second. one people also got different placebos. Some god benign nina cockles solution and some a saline solution. That could mean nothing. But it's also unusual to have two. Placebos sends that has the potential to introduce con founders into the study and because of limited supplies. Some study participants had to wait more than the three to four weeks originally planned between their doses while others when told they couldn't come back for their second dose at the time they expected chose to simply not get their second shot entirely. Frankly the way they did. These trials was really confusing. Says dr paul off it. Director of the vaccine education center at children's hospital of philadelphia and a member of the us food and drug administration's advisory committee that reviews vaccines for authorization or approval. This is the stuff you figure out in phase one. You don't fool around in phase three and see what works he says. Here's what the researchers report after getting a single shot. Seventy six percent of participants were protected against disease for up to three months. Afterwards from their their levels of antibodies generated against the virus which scientists believe are important to protect against disease began to drop those results suggest that while two doses of the astra. Zeneca vaccine preferable. A single dose could still be useful for about three months in controlling covid. Nineteen that might be especially useful information to act on if vaccines are in. Short supply.

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