Football, President Trump, Two Million Dollars discussed on Charlie Brennan


Hating our right to what what what your mascot will will shout go whatever. I don't think we have a mascot we're just a lot but we can certainly use why no football team playing tomorrow Saturday now sorry about that well none the less we still appreciate your work because of the president ran on lowering prescription drug prices I think everybody wants that and now you've written that there is a law however well intended called the orphan drug law which seems to do the opposite of what it probably was intended to do we thought maybe would provide incentives for people to create new drugs even though they might be very costly to produce and research but now as it turns out a lot of drugs that have been around for quite some time are being called orphan drugs and when the drug is labeled an orphan drug that means that no one can compete with that for seven years and that means the distributor the manufacturer can just Jack up those prices and you know one person whose prescription drugs cost two million dollars. your son drug act which was started for very good reasons is part of what had been effective pushing us into X. really expensive drugs and particularly in to cancer drugs that that may not necessarily be very effective. your drug act is supposed to create incentives for people to work on rare diseases when they would be so few patients that a drug company couldn't recover money from it instead companies now to hate an individual set of patients and they what they do is called salami slicing they consider a little tiny piece of the patient population another little tiny piece and another tiny piece and at the end of the day a big population gets extraordinary protection and extraordinary prices without necessarily extraordinary movement forward in treating them you mentioned in your piece that in the orphan drug act if the disease affects fewer than two hundred thousand people that a company could enjoy the benefits of the orphan drug act and that number was not selected economically or scientifically but basically so it could include narcolepsy and multiple sclerosis. yes the passage of the orphan drug act was a very odd moment in congressional history it was it was full of drama and and celebrities and you know heart wrenching stories but it didn't necessarily produce the best piece of legislation in fact when the orphan drug act was passed a famous Hollywood star came in re enacted essentially is dramatization on a public a popular television show needed that before Congress I was extraordinarily moving and of course who could who could oppose the orphan drug act I mean my goodness it sounds as if it was taking care of abandoned and neglected children. yeah that was Jack Klugman in fact when he was I think it shows call Quincy it but likely at the regular line was we need legislation he was always saying you know for this problem that probably need legislation so we got this legislation in real life and it's all fine and good because it should help companies that would have very expensive research and development costs producer drugs you know in other words if you produce something that's really helpful you should enjoy certain market protections the problem is and I think you can lay this out is that let's take lung cancer they could find one kind of new ones section of the lung cancer market and say that this drug is for that very small group and then you could take an existing drug called an orphan drug and then all competition has to go away for a certain period of time and that drives of drug prices. if you look at the numbers they're very clear orphan drug designation was meant for little tiny areas where there would be no return now or sing drug designation is associated with dollar return so out of the ten drugs with the highest annual revenue in two thousand fifteen seven orphan drugs that's not what was intended. no now tell us about this two million dollar prescription only. he is this is this is a drug to treat a debilitating genetic disorder and the cost last year to treat one patients two million dollars so there is a Haitian was covered in in the press with an extraordinary story it's a very important drugs for her and her hundreds came to her husband's health plan which was your husband labor unions so for that labor unions thirty five cents of every hour Hey for each of the unions sixteen thousand workers went to pay for her prescriptions for that one dog one single patient all those people are working to pay the cost of that one drugs something wrong with the economics there now you might say all it's all worth it because people are living longer professor. not a as well many of the orphan drugs are in cancer therapeutics and they're they're not necessarily having the kind of results that we would hope for so we are staying with this orphan drug in the shift cancer therapeutics we have seen some areas with important moved forward in cancer treatment so some areas like breast cancer and some of the lymphomas have had extraordinary progress but on the whole progresses been nearly disappointing so do you think about the new cancer drugs approved between two thousand and three and two thousand and thirteen those increased overall survival by an average of only three and a half months that's not very much yeah and in fact the open please no go ahead. what is the overall death rate from cancer has fallen only five percent since nineteen fifty and some scholars attribute that primarily to the decline in smoking and those are the numbers that really struck me that shocking five percent since nineteen fifty possibly due to just the decline in smoking there seems to be this disconnect with the national narrative of beating can't beating cancer you of Biden's moon shot moments right they were going to cure cancer so there's a disconnect between the national narrative and of the funds and where those funds are going with in the pharmaceutical companies and and you make the argument there needs to be more focused if there are going to be any real gains in fighting cancer. if we want to do a cancer moon shot we have to do right we have to do it in a way this ineffective we can't simply back into it side ways with systems like orphan drug designation that encourage companies to just recycle existing drugs that may have small improvements are small benefits one often moon shots in one at a cancer moon shot we should do it with our eyes open and do it carefully so that we have the possibility to get the kinds of returns we like cancer is never going to be easy to solve but we are unlikely to make the kind of progress we want unless we do it bottle in carefully now professor Feldman indeed some lives are being extended through new treatments at places like Washington university and elsewhere in childhood leukemia was a death sentence is not anymore and I think the same is also true for aids so some of these prescriptions really are extending lives are they not. we have had extraordinarily important movement forward in areas of cancer in some other areas that are within orphan drug designation these are these are these are extremely important and one can say that each small increments may be a step forward never know which will get us there but on the whole we really aren't getting the return that we ought to be we have to stand back as the sister then asked if we are putting all of his energy into recycle drugs it may not move very much forward what are we not putting our energy into and the easy answer for that is antibiotics the research in in antibiotics for resistant drugs has declined dramatically even though we know that that is an extraordinarily important area of of of public health there's a U. K. report anticipating ten million deaths a year by twenty fifty from drug resistant bacteria in yet researching the antibiotics faces declining because well companies can't make as much money but. fascinating robin Feldman author of drugs money in secret handshakes the unstoppable growth of prescription drug prices thank you so much for joining us again on cam works in Saint Louis and best everybody at U. cal Hastings. thank you for having me thank you so much all right we'll take phone calls and you can always get in on the one line four four four three thousand around the corner what's the latest from the Mayo Clinic when it comes to vaping this might surprise you we've got some of those details also this morning. all men want to tell you a little something about our friends who are in Andreas steak house why do I love them well let me count the ways number one they've got the best baked potato in the greater St Louis area just ask Saint Louis restaurant news it's not made like a traditional baked potato instead it's cooked in parchment and bake down rock salt and they open it at the table it's a glorious experience how about their burger only available at the bar I think this burger is clearly the best in the state of Illinois and it's definitely top five in the Midwest it's only available in the bar so after eighteen holes of golf nearby when a drop by and get a cold brew ski and the burger you will it's it's made with entries brush on steak sauce which is a steak sauce that you can get at any grocer or injuries dot com and it'll improve any cut of meat how about to injuries he's Barghouti butter cake it's the most popular item in the menu on the menu even though it was made by mistake owner Larry Kennison which is due for around the kitchen he made this and now the heath Barkley bar cake is number one however oxtail soup I actually did see an oxtail soup in Europe I haven't seen one of the states in years it takes Larry's brother about four hours repair this it's really delicious and about four five Bucks of boards great prices too I might mention that they've got outstanding steaks as well Andreas on all counts will road in o'fallon Illinois..

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