In Science Translational Medicine, North Carolina State University, PAT discussed on This Week in Science
My point. Is I have enough problems with my vision. I like I could really value I. I absolutely do it if I was losing my sight. And this is what it would take totally absolutely lady up and if these entities especially if they last for a long period of time. I mean six years. That's okay you don't WanNa be doing brain surgery every six years. That's a bit much. But at the same time if they develop this a bit further and they can get them to last even longer it's potentially With potentially something that a lot of people would sign up for potentially and then really kind of quick one that I think is very exciting. I have reported previously on Repair mechanisms for the heart. There aren't any real natural repair mechanisms for the heart. Once you've had a heart attack Researchers from North Carolina State University have published in In Science Translational Medicine about their off the shelf artificial cardiac patch there is slap it onto the heart and fix it after a heart attack. That's not exactly what happens. No they look at a rat model of heart attack and they also did a pilot. Study involving pigs so pig. Hearts are much more similar to human hearts In these models of heart attack they applied these cardiac patches and the patches are interesting because they They took they created a scaffold from pig cardiac tissue they D- cellular realized basically. It's just the extra cellular stuff that holds the cells together. The got rid of the cells. And it's just the extra cellular matrix and then instead of growing new sows in it. They created what they're calling a synthetic the they put in synthetic cardiac strom all cells and these being synthetic. It's not really sells. It's a biodegradable. Polymer that has a mix of Strobl cell-derived repair factors that come from heart cells. So they've got the scaffolding they've got the repair factors all stuffed into the holes where the cells normally go and They can put it in the freezer if they want. But they put it on a on a rat heart that had gone through heart attack and they've found that the patch resulted in about fifty percent improvement of cardiac function. You Body what it needs to do. The job and your body will likely do the job for so I think I was wearing. This is sort of like bringing all the repair materials and incentives to repair network around the. Yeah and I think that's. That's what they're finding is. Potentially the best the best pathway moving forward toward repairing the heart because they're finding that We can't induce stem cells in the heart to do anything You could do cell transplants into the heart and try and get them to do stuff but then you might have rejection issues And so this is kind of solves all the problems because you don't have to deal with with cells that have been transplanted from somebody else. You're looking at just the repair stuff and your own body then picks it up and does the work and does an fixes it. It just needs that little little boost make it go potentially so this is looking very promising. in the pigs there was also About thirty percent reduction in scarring in some areas of the pig heart as well as stabilized art function compared to non treatment and the patch that they have created can be frozen and safely stored for at least thirty days. Because there's no live cells involved. It say what they're what they're saying off the shelf. It's the kind of thing that you could have like a band aid at. A hospital accepted to heart band aid cardiac behind it is oh you you had a heart attack. We'll put a band aid on that but heart pat. Pat Will Patch you up. It's a new meaning repacking. Somebody up moving forward. It's I think it's very interesting work and I'm very excited about it But at this point it's not time for me to be excited anymore really. I mean it's time for other things. It's time to move forward in the show. And if you are interested in a twist shirt.