Clinton Wiley, Today, University Of Pittsburgh discussed on ResearchPod



Hello and welcome to research pod. Thank you for listening and joining us today. In this episode we will be looking at the research of professor clinton wiley from the university of pittsburgh professor widely studies the emergence of new. Brian viral infections hunter linked to dementia. It took humans millions of years to evolve on become who we are today. Viruses are much faster existing viruses. We are already familiar with can evolve kohl's occasional epidemics like the virus responsible for the annual flu. Humans have learned to cope with those. But sometimes you viruses emerge and take us by surprise on some of them can even disrupt our daily lives by causing pandemics. Something we know all too well and twenty twenty one. A virus has made of genetic material dna or any that is contained inside a protective envelop with proteins. On a surface to survive and thrive it needs a host for example. A human once. The host is infected the virus exploits the host sale machinery to replicate to do that. The virus i haas to bind to enter a host sal. The viral genetic material is a code that indicates to synthesize every component of the virus inside the host sale thousands of envelope. Proteins and copies of the genetic material are synthesized campbell into new viral particles. These viral particles are then released to spread within the host uninfected other sales to keep replicating the virus then moves onto another host. A broad range of strategies enabled transmission from one host to another viruses known as enteroviruses for example replicate in the host gut unreliable on hand to mouth. Contact tune fact. A new host other viruses called arba viruses are finding blood. There transmission is facilitated by vectors such as mosquitoes or ticks high is our body defend itself against viruses and hit unadopted. Immunity are host defense mechanisms. The prevent viruses from growing inside of ourselves and yet immunity includes physical and biochemical barriers skin for example axes barter on constitutes the first line of defense against invading pathogens such as viruses on bacteria mucus in the nose as another example of a bar et can trap viruses in the air we breathe and yet immunity also has a role to play a viruses managed to enter the body. Despite the physical barriers viruses are recognized as foreign elements by hosts sales this recognition triggers the destruction of the pathogen adoptive. Immunity involves molecules such as cytokines. Antibodies which neutralize viruses on sales which kill infected hosts sales the adaptive immune system has a memory. It remembers initial pathogen infections. So that with subsequent encounters the protective responses. More a bust on defective..

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